Maxheal Surat Mhra Plant 26 Oct 2008
-
Upload
sanjay-gawali -
Category
Business
-
view
2.391 -
download
3
description
Transcript of Maxheal Surat Mhra Plant 26 Oct 2008
Maxheal Laboratories Pvt. Ltd.
1
Welcome to thePresentation
on Maxheal Laboratories
Pvt. Ltd.
Maxheal Laboratories Pvt. Ltd.
2
PROJECT INFORMATION1.1) Brief Description of Project
M/s. Maxheal Pharmaceuticals Pvt Ltd. envisages to build a Formulation manufacturing facility for Non Betalactum at Taluka Sachin, Dist. Surat for solid dosages in the form of Tablet and Capsule, Ointment in a self contained dedicated unit as per local FDA and international regulatory requirements like MHRA, USFDA, TGA, WHO GMP, etc.
Maxheal Laboratories Pvt. Ltd.
3
PROJECT INFORMATION1.2) Site Selection Criteria
The proposed facility will be located in lush green and free from air pollution and having good quality of ground water. Also all surrounding units are non polluting and pharma friendly at 20 KM away from Surat at Gujarat (INDIA).
Project Location : At Taluka, Sachin, Dist. Surat, Gujarat, INDIA
Maxheal Laboratories Pvt. Ltd.
4
PROJECT INFORMATION1.3) Land Area : Plot Area 13000 Sq. Mt.
Season Dry Bulb Relative Humidity
Temp.
Summer 40.0˚C70%
Winter 28.0˚C50%
Monsoon 30.0˚C 85%
Maxheal Laboratories Pvt. Ltd.
5
PRODUCTION CAPACITYNON BETALACTUM
Sr. No.
Particulars Capacity Per Shift
Per Month Per Year
01.0 Tablet (Uncoated / Coated)
2 Million 50 Mill. 600 Mill.
01.1 Capsule (Hard Gelatin)
0.8 Million 20.83 Mill. 250 Mill.
01.2 Ointment (30 gm) 20 Thousand Tubes.
0. 5 Mill. 6.0 Mill.
Maxheal Laboratories Pvt. Ltd.
6
QUALIFICATION OF PRODUCTION MACHINE
Maxheal Laboratories Pvt. Ltd.
7
PRODUCTION QUALIFICATION
4.1 Assumptions:
4.1.1 300 working days per annum.
4.1.2. Working hours 8 per shift/ day.
4.1.3. Production days 25 per month.
4.1.4 Production planning is based on per shift basis
Maxheal Laboratories Pvt. Ltd.
8
4.3 Proposed Granulation:-
Granulation I :- (Batch Size 360 Kgs)
120 Kg Fluid Bed Processor. ( Gr-1)
Sifter 30 inches. , comill, Lifter.
3 lot from fabrication per shift total granules production for 360 Kg per shift.
600 & 1800Litres Blender with Bulk density of 0.6 In process Bins of 110 to 300 Kg for transfer to compression machine.
Output: 300 kg per day per shift x 21 days.
Maxheal Laboratories Pvt. Ltd.
9
Granulation II :- (Batch Size 720 Kgs)
240 Kg Fluid Bed dryer.
240Kg Rapid Mixer and granulator.
Sifter 30 inches. , comill, Lifter.
3 lot from fabrication per shift total granules production for 720Kg per shift.
600 & 1800 Liters Blender with Bulk density of 0.6
In process Bins of 110 to 300 Kg for transfer to compression machine.
Output: 720 kg per day per shift x 21 days
Maxheal Laboratories Pvt. Ltd.
10
Compression Area
4.4.1 Compression 2 Nos. Cubical Recommended.
Total Output 1080 Kg x 400mg Tablet / Shift ~ 2.0 Million /Shift.
Coating Area
Coating (2 Nos.) 0ne Pan 48” and one pan 60 inches
Maxheal Laboratories Pvt. Ltd.
11
Capsule
Capsule filling room 2 Nos :- 2.0 Million / Day. Average Weight 250 mg, granulation required 250 kg per shift.
Recommended 1 Blender of 900 kg.
Capsule filling sealing Machine capacity 0.9 million / shift x 2 Machine.
Maxheal Laboratories Pvt. Ltd.
12
Ointment Manufacturing Area:-
Manufacturing vessel 750Kg of Pharma tech Mumbai
Tube filling GAN + LS-120 of Wimco
Capacity 50000 Tubes per shift
Total Output 20000 Tube x 30 grams Tubes / Shift ~ 0.02 Million /Shift.
Maxheal Laboratories Pvt. Ltd.
13
Packing area ( 6 Primary packing Line)
Total Packing requirement 3.0 Million tablet , capsule/ Shift.
Blister (240 Size) x 2 Lines.
ALU- ALU: 1 Line
Strip Packing: 1 Line
Total Packing = 25.0 million/shift
a) Tube Filling x 1 Lines.
Total Tube Packing = 0.050 million/shift
Maxheal Laboratories Pvt. Ltd.
14
Formulation R&D :-
• We have Formulation R&D for Tablets ; Capsule and Ointments Section.
• Capacity is 5 Kg
• All machine are identical with Plant Machinery
Maxheal Laboratories Pvt. Ltd.
15
Process Flow ChartTablet
DISPENSED RAW MATERIALS
MIXING
BLENDING
MILLING
DRYING
SIFTING
QC (HOLD)
COMPRESSION
QC HOLD
COATING
PRIMARY PACKING IN BLISTER/ STRIP/ BULK
INSPECTION
FINISHED GOOD STORE [QUARANTINE / APPROVED]
QC HOLD
SECONDARY PACKING
Maxheal Laboratories Pvt. Ltd.
16
Process Flow ChartCapsule DISPENSED RAW
MATERIALS
TO -------DRYING (OPTIONAL)
SIFTING
MILLING
REJECT (HOLD)-------BLENDING
TO-----------QC (HOLD )
FILLING AND POLISHING
REJECT (HOLD )--------TO-----------QUARANTINE ( HOLD)
BLISTER STRIP BULK
FINISHED GOODS STORE [ Quarantine OR Approved ]
Maxheal Laboratories Pvt. Ltd.
17
DISPENSED RAW MATERIALS
SIFTING OF DRUGS
OINTMENT BASE PREP DRUGS
MIXING & EMULSIFICATION
TUBE FILLING & CRIMPING
Quarantine ( Hold)
FINISHED GOODS STORE
TO QC FOR APPROVAL
Ointment
Maxheal Laboratories Pvt. Ltd.
18
Maxheal Laboratories Pvt. Ltd.
19
Maxheal Laboratories Pvt. Ltd.
20
AREA QUALIFICATION
Maxheal Laboratories Pvt. Ltd.
21
Area Statement
Plot Area : 13000 Sq. Mt.Production Block Ground Floor : 2625 Sq.Mt.Production Block Mazzanan Floor : 1207 Sq. Mt.Production area at First Floor : 2625 Sq.Mt. Production area at Second Floor : 1324 Sq.Mt. Total ( A) : 7781 Sq.MtADM+ QC/ R&D Area GF : 324.30 Sq MtADM+ QC/ R&D Area FF : 324.30 Sq MtADM+ QC/ R&D Area SF : 324.30 Sq Mt Total ( B) : 972.9 Sq.Mt Utility Block GF : 362.34 Sq Mt Utility Block FF : 362.34 Sq MtUtility Block SF : 67.86 Sq MtSecurity Cabin ( 1+2) : 60.00 Sq.Mt. Total ( C) : 852.54 Sq.Mt
Total Area : 9606.44 Sq Mtr (1,066,27 Sq. Foot )
Maxheal Laboratories Pvt. Ltd.
22
MASTER SITE PLAN
Maxheal Laboratories Pvt. Ltd.
23
MASTER SITE PLAN
Maxheal Laboratories Pvt. Ltd.
24
MAIN PRODUCTION BLOCK
Maxheal Laboratories Pvt. Ltd.
25
GROUND FLOOR PLANGROUND FLOOR PLAN
Maxheal Laboratories Pvt. Ltd.
26
MAZZANINE FLOOR MAZZANINE FLOOR PLANPLAN
Maxheal Laboratories Pvt. Ltd.
27
FIRST FLOOR PLANFIRST FLOOR PLAN
Maxheal Laboratories Pvt. Ltd.
28
SERVICE FLOOR PLANSERVICE FLOOR PLAN
Maxheal Laboratories Pvt. Ltd.
29
MACHINE LAYOUT PRODUCTION BLOCK
Maxheal Laboratories Pvt. Ltd.
30
FIRST FLOOR PLAN (WITH MACHINE FIRST FLOOR PLAN (WITH MACHINE LAYOUT)LAYOUT)
Maxheal Laboratories Pvt. Ltd.
31
MOVEMENTS PRODUCTION BLOCK
Maxheal Laboratories Pvt. Ltd.
32
Movements Ground Floor
Maxheal Laboratories Pvt. Ltd.
33
Movements First Floor
Maxheal Laboratories Pvt. Ltd.
34
FINISHING DETAILSPRODUCTION BLOCK
Maxheal Laboratories Pvt. Ltd.
35GROUND FLOOR GROUND FLOOR
FINISHINGFINISHING
Maxheal Laboratories Pvt. Ltd.
36FIRST FLOOR FINISHINGFIRST FLOOR FINISHING
Maxheal Laboratories Pvt. Ltd.
37
HVACPRODUCTION BLOCK
Maxheal Laboratories Pvt. Ltd.
38GROUND FLOOR WITH AREA GROUND FLOOR WITH AREA
CLASSIFICATIONCLASSIFICATION
Maxheal Laboratories Pvt. Ltd.
39FIRST FLOOR WITH AREA FIRST FLOOR WITH AREA
CLASSIFICATIONCLASSIFICATION
Maxheal Laboratories Pvt. Ltd.
40GROUND FLOOR WITH PRESSURE GROUND FLOOR WITH PRESSURE
GRADIENTGRADIENT
Maxheal Laboratories Pvt. Ltd.
41FIRST FLOOR WITH PRESSURE FIRST FLOOR WITH PRESSURE
GRADIENTGRADIENT
Maxheal Laboratories Pvt. Ltd.
42GROUND FLOOR WITH AHU ZONINGGROUND FLOOR WITH AHU ZONING
Maxheal Laboratories Pvt. Ltd.
43FIRST FLOOR WITH AHU ZONINGFIRST FLOOR WITH AHU ZONING
Maxheal Laboratories Pvt. Ltd.
44MAZZANINE FLOOR WITH AHU MAZZANINE FLOOR WITH AHU
LOCATIONLOCATION
Maxheal Laboratories Pvt. Ltd.
45SERVICE FLOOR WITH AHU LOCATIONSERVICE FLOOR WITH AHU LOCATION
Maxheal Laboratories Pvt. Ltd.
46
ELECTRICALPRODUCTION BLOCK
Maxheal Laboratories Pvt. Ltd.
47GROUND FLOOR LUX LEVELGROUND FLOOR LUX LEVEL
Maxheal Laboratories Pvt. Ltd.
48FIRST FLOOR LUX LEVELFIRST FLOOR LUX LEVEL
Maxheal Laboratories Pvt. Ltd.
49ELECTRICAL MASTER PLANELECTRICAL MASTER PLAN
SHEET -1SHEET -1
Maxheal Laboratories Pvt. Ltd.
50
SHEET -2SHEET -2
ELECTRICAL MASTER PLANELECTRICAL MASTER PLAN
Maxheal Laboratories Pvt. Ltd.
51
SHEET -3SHEET -3
ELECTRICAL MASTER PLANELECTRICAL MASTER PLAN
Maxheal Laboratories Pvt. Ltd.
52
SHEET -4SHEET -4
ELECTRICAL MASTER PLANELECTRICAL MASTER PLAN
Maxheal Laboratories Pvt. Ltd.
53
ELECTRICAL LOAD SUMMARYELECTRICAL LOAD SUMMARY
Maxheal Laboratories Pvt. Ltd.
54
ADM/QC BLOCK
Maxheal Laboratories Pvt. Ltd.
55
GROUND FLOOR PLAN GROUND FLOOR PLAN
(ADM OFFICE)(ADM OFFICE)
Maxheal Laboratories Pvt. Ltd.
56
FIRST FLOOR PLANFIRST FLOOR PLAN
Maxheal Laboratories Pvt. Ltd.
57
SECOND FLOOR PLAN SECOND FLOOR PLAN (QC/R&D)(QC/R&D)
Maxheal Laboratories Pvt. Ltd.
58
UTILITY BLOCK
Maxheal Laboratories Pvt. Ltd.
59
GROUND FLOOR PLANGROUND FLOOR PLAN
Maxheal Laboratories Pvt. Ltd.
60
SECOND FLOOR PLANSECOND FLOOR PLAN
FIRST FLOOR PLANFIRST FLOOR PLAN
Maxheal Laboratories Pvt. Ltd.
61WATER REPORTWATER REPORT
Maxheal Laboratories Pvt. Ltd.
62
PURIFIED WATER GENERATION SYSTEMPURIFIED WATER GENERATION SYSTEM
Maxheal Laboratories Pvt. Ltd.
63
PURIFIED WATER DISTRIBUTION PURIFIED WATER DISTRIBUTION SYSTEMSYSTEM
Maxheal Laboratories Pvt. Ltd.
64
P&I DIAGRAM FOR STEAM P&I DIAGRAM FOR STEAM DISTRIBUTION DISTRIBUTION
Maxheal Laboratories Pvt. Ltd.
65
P&I DIAGRAM FOR COMPRESSED AIR P&I DIAGRAM FOR COMPRESSED AIR
Maxheal Laboratories Pvt. Ltd.
66
P&I DIAGRAM FOR STEAM P&I DIAGRAM FOR STEAM DISTRIBUTION DISTRIBUTION
Maxheal Laboratories Pvt. Ltd.
67
Contact
• Maxheal Laboratories Pvt.Ltd
Head OfficeContact Person:Mr. Madan Sakhala, (MD)
• Address :103, Tulsi Niwas, Pushtikar Cooperative Society Ltd., Jogeshwari (W)Mumbai, Maharashtra - 400102, India
• Phone No:+ (91)-(22)-26786103/26786104Fax No:+ (91)-(22)-26786105
• E-mail :[email protected], [email protected]
Maxheal Laboratories Pvt. Ltd.
68
Thank You