Enzyme Immobilization on Polyether or Proteinaceous Supports.
Mass Spec & NMR Analysis of Polyester and Polyether Polymers Alex Dospinoiu 4/18/09.
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Transcript of Mass Spec & NMR Analysis of Polyester and Polyether Polymers Alex Dospinoiu 4/18/09.
![Page 1: Mass Spec & NMR Analysis of Polyester and Polyether Polymers Alex Dospinoiu 4/18/09.](https://reader036.fdocuments.in/reader036/viewer/2022062408/56649de65503460f94adf811/html5/thumbnails/1.jpg)
Mass Spec & NMR Analysis of Polyester and Polyether Polymers
Alex Dospinoiu4/18/09
![Page 2: Mass Spec & NMR Analysis of Polyester and Polyether Polymers Alex Dospinoiu 4/18/09.](https://reader036.fdocuments.in/reader036/viewer/2022062408/56649de65503460f94adf811/html5/thumbnails/2.jpg)
Interned with:
• Dr. Henry Hall– University of Arizona– Department of Chemistry– Research focus:• Organic Monomer &
Polymer Chemistry
– Special thanks• Dr. Robert Bates
![Page 3: Mass Spec & NMR Analysis of Polyester and Polyether Polymers Alex Dospinoiu 4/18/09.](https://reader036.fdocuments.in/reader036/viewer/2022062408/56649de65503460f94adf811/html5/thumbnails/3.jpg)
Research:
• Cannot disclose specifics• Research being conducted is done for a
company– They provide multiple samples– Ask for in-depth structural analysis
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So what can I present on:
• If I cannot present specifics …
• Lets go back to basics:– What is a polymer– What are polyester and polyether polymers– Mass Spectroscopy– Nuclear Magnetic Resonance (NMR)– Why the interest in these polymers
![Page 5: Mass Spec & NMR Analysis of Polyester and Polyether Polymers Alex Dospinoiu 4/18/09.](https://reader036.fdocuments.in/reader036/viewer/2022062408/56649de65503460f94adf811/html5/thumbnails/5.jpg)
Polymer
• from Greek πολύ-ς /po΄li-s/ much, many and μέρος /΄meros/ part)
• Essentially– A large molecule– Repeating structural units
• Classifications– Synthetic: Nylon, Teflon– Natural: proteins (wool, silk) DNA, RNA,
polysaccharides (cotton)
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Polyesters
• Used to make:– Bottles, films, canoes, LCDs,
• Characteristics– Low water absorption– Low toxicity– Good mechanical properties
• Example– PET (Polyethylene
terephthalate)
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Polyethers
• Used to:– Bring together a non-polar compound and water
• Characteristics:– Very low chemical reactivity• Low toxicity
– Much more polar than most organic polymers• Great water solubility
• Example– PEG (Polyethylene glycol)
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Mass Spectroscopy
![Page 9: Mass Spec & NMR Analysis of Polyester and Polyether Polymers Alex Dospinoiu 4/18/09.](https://reader036.fdocuments.in/reader036/viewer/2022062408/56649de65503460f94adf811/html5/thumbnails/9.jpg)
Results of Mass Spec
• MWt– H -- 1– C -- 12– N -- 14– O -- 16
![Page 10: Mass Spec & NMR Analysis of Polyester and Polyether Polymers Alex Dospinoiu 4/18/09.](https://reader036.fdocuments.in/reader036/viewer/2022062408/56649de65503460f94adf811/html5/thumbnails/10.jpg)
What we have observed:
• We are looking at low molecular weight oligomers– We have found the molecular formula
“exact” MWt CxHyOz
– But we want the structural formula• Using Mass Spec/Mass Spec technique
MWt CxHyOz
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Nuclear Magnetic Resonance
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Results of NMR
![Page 13: Mass Spec & NMR Analysis of Polyester and Polyether Polymers Alex Dospinoiu 4/18/09.](https://reader036.fdocuments.in/reader036/viewer/2022062408/56649de65503460f94adf811/html5/thumbnails/13.jpg)
What we have observed
• NMR is not the best technique because we have a wide range of molecular weights
• Has not been used much with these particular samples
![Page 14: Mass Spec & NMR Analysis of Polyester and Polyether Polymers Alex Dospinoiu 4/18/09.](https://reader036.fdocuments.in/reader036/viewer/2022062408/56649de65503460f94adf811/html5/thumbnails/14.jpg)
How does this apply to NASA?
• These polymers are resistant to oxidation– Could potentially be used to store the liquid
oxygen fuel– Decrease in weight needed to be lifted
- A lot of issues left to be worked out
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Questions?