MALMÖ SWEDEN MAY 28 - JUNE 2, · New to ESPID! You may keep track of your session attendance by...

Meeting Website: https://espidmeeting.org/2018 ESPID Website: www.espid.org

Also referred to as ESPID 2018Jointly organized by ESPID and the Danish and Swedish Paediatric Infectious Diseases Societies

36TH ANNUAL MEETING OF THE

MALMÖ SWEDEN

MAY 28 - JUNE 2,2018

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CONTENTSMeeting Information

Welcome to ESPID 2018

General Information

Venue Floor Plan

Awards

Information for Presenters

CME/CPD Accreditation

Optional Networking Events Programme

Programme at a Glance

Monday, May 28

Tuesday, May 29

Wednesday, May 30

Thursday, May 31

Friday, June 1

Saturday, June 2

Recognition, Acknowledgments and Industry Support

Acknowledgements

Pre & Post Meeting Industry Supported Symposia

Exhibition Floor Plan

List of Exhibitors

ESPID European Society for Paediatric Infectious Diseases

SUPPORT OUR SOCIETY! RENEW YOUR MEMBERSHIP OR JOIN ESPIDESPID – PROMOTING EXCELLENCE IN PAEDIATRIC INFECTIOUS DISEASES AND CHILD HEALTHBENEFITS OF MEMBERSHIP• Annual online subscription to the Pediatric Infectious Disease

Journal (PIDJ) - 12issuesper year.Paperversionalso available for an additionalfee.

• Greatlyreducedregistrationfeesfor theESPIDAnnualmeeting• Online courses• Case rounds• ESPID sponsored courses throughout Europe• Webcasts,slideshowsandpostersfromtheAnnualESPIDMeeting• ESPID Fellowships and Awards schemes• Voting rights• Facilitatedparticipationina numberofprestigiousscientificcourses• Under40yearsold?JoinYoungESPID!

••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••••

If youhavenot renewedyourmembership forseveralyears,youcanrejoin thesocietypaying only the subscription for the current year!

For further information or to join ESPID please visit www.espid.org.ESPID SecretariatEmail: [email protected]: +44 1506 292029

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WELCOME TO ESPID 2018 Dear Friends and Colleagues,

On behalf of the Local Organising Committee (LOC) and the International Scientific Committee (ISC), it gives us great pleasure to welcome you to the 36th Meeting of the European Society for Paediatric Infectious Diseases (ESPID) in Malmö, Sweden. The Meeting is jointly organized by the Danish and Swedish Paediatric Infectious Diseases Societies and brings together the most prominent researchers in the field of paediatric infectious diseases, epidemiology and immunology. This year's host city Malmö, at the southern tip of Sweden is a young, global and vibrant city with its neighbour Copenhagen, the wonderful capital of Denmark just across the famous Oresund bridge. We will interact with PID colleagues from many different countries for creative exchange of thoughts and ideas! We are pleased to have you in Malmö.

Sincerely,

Lise Heilmann Jensen Olof Hertting

Chairs, ESPID 2018 Meeting

On behalf of the Local Organising and International Scientific Committees

Enjoy the complete meeting experience

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Real-time updates

In-session voting

e-Poster presentations

Session evaluations

Programme and speaker details

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GENERAL INFORMATIONVENUEMalmömässanMässgatan 6215 32 MalmöSwitchboard: +46 40 631 11 10info(a)malmomassan.sewww.malmomassan.se

LANGUAGEThe official language of the Meeting will be English. All abstract presentations should be presented in English.

REGISTRATION DESK HOURSMonday, May 28 11:30- 20:00Tuesday, May 29 07:15-19:00Wednesday, May 30 06:30-18:00Thursday, May 31 06:30-18:30Friday, June 1 06:30-17:30

EXHIBITION HOURSTuesday, May 29 09:00-19:30 *Wednesday, May 30 09:00-16:30Thursday, May 31 09:00-16:00Friday, June 1 09:00-17:30*End of Welcome Reception

TOURIST INFORMATIONPlease visit the staffed info point at the shopping center Emporia, across the street from Malmömässan to receive more information about Malmö icluding tourist information, maps etc.

NAME BADGESAll participants and exhibitors are requested to wear their name badges throughout the Meeting and present vouchers for social events to be admitted to the lecture halls and scheduled activities.

WIFI Free WIFI is available to Meeting participants in public areas and in the Exhibition Area.NETWORK NAME: ESPID2018 PASSWORD: ESPID2018

CME/CPD CERTIFICATE OF ATTENDANCEThe CME/CPD certificate of attendance will be available for participants after the Meeting. Your certificate will be delivered electronically after completing the educational evaluation procedure online via the link you will receive following the Meeting.

SCIENTIFIC MOBILE APP Install the ESPID 2018 app to access all the information you may need during the Meeting. Sign in to the app using your registration ID number (found on the back of your badge).

• Programme and speaker details

• Real-time updates

• E-Poster presentations

• In-session voting

• Session evaluations

• Ask the speaker questions

• Email speakers

• And more

Download the ESPID 2018 App now to enhance your Meeting experience! (Select your app store below to download directly).

View on

Mobile Website

View on

Mobile Website

E-POSTERSESPID 2018 is pleased to announce that selected presentations at the Meeting will also be available for viewing as E-posters, available online and via the Meeting Mobile App during and after the Meeting. E-Posters are made available to delegates through numerous large electronic screens sited in the congress centre throughout the Meeting. The E-poster platform allows users to browse by topics, search for specific content and submit questions to the authors. You may view the E-posters on the stands in the E-Poster Area, where any E-Poster can be viewed on any screen at any time or on your personal device.

INVITED SPEAKER & ORAL PRESENTATIONS Presentations by invited speakers and oral presenters giving a formal lecture are available in PDF format that can be opened in 3rd party apps on mobile devices and PCs, via the Mobile App. These presentations will also be made available on the ESPID website after the Meeting.

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ABSTRACTS Abstracts will be accessible to all delegates via the Meeting App during and after the Meeting.

WEBCAST All plenaries and symposia will be video recorded and webcasts will be available after the Meeting through ESPID.org.

VIRTUAL LIBRARYSubject to authors’ consent, invited speaker and oral slide sets will be made available during the Meeting on the Mobile App and later on the website with audio recordings of the talks. E-Posters will likewise be made available on the Mobile App and later on the Meeting website, and authors are also encouraged to upload an explanatory audio file.

MEET THE PROFESSOR SESSIONSMeet the Professor Sessions will be held on Wednesday, May 30, 2018 and Thursday, May 31 between 07:00 and 07:50. There is no need to pre-register for these sessions. If the room is full you may need to choose to attend a different session. Meet the Professor Sessions provide participants the opportunity to be updated about a topic of interest in a highly interactive manner. Meet the Professor Sessions at the 2018 Meeting will consist of interactive case-based discussions each with a coordinator who will select and present cases and two expert discussants. The chairs may frequently use case reports with questions regarding diagnosis and management. Please view the programme for further details on these sessions.

RESEARCH SESSIONSResearch Sessions will take place on Thursday, May 31, 2018 between 14:00 and 15:30. Attendance in these sessions is open to ESPID members only. Sessions will be limited to 30-40 participants. There is no need to pre-register for these sessions. If the room is full you may need to choose to attend a different session. Please refer to the Mobile App or programme to view the topics of these sessions.

NETWORKING BREAK/LUNCH Prepaid lunch is available in the exhibition area. To purchase lunch on site, visit the cafeteria or cash bar located near the registration desk. The cash bar and cafeteria will be open only during the networking breaks.

RECOGNITION, ACKNOWLEDGEMENTS & INDUSTRY SUPPORTIn accordance with compliance regulations, Industry supporting the Meeting will be acknowledged separately from the scientific programme. Industry information appears at the back of the book, under the section Recognition, Acknowledgements and Industry Support.

ATTENDANCE TRACKINGNew to ESPID! You may keep track of your session attendance by scanning your badge, when prompted, at the entrance to the halls. ESPID will be collecting attendance data during the Meeting using RFID tracking technology tounderstand participation patterns, improve the meeting, and develop new services for the delegates. After the Meeting, you will be sent a link that will provide you with your ESPID 2018 attendance data. Thank you for your participation.

GUEST ATTENDANCE POLICYAll event activities (including sessions, meal functions, exhibit hall, etc.) are exclusively reserved for registered attendees. Non-registered guests (including children, family members, colleagues, etc.) are not allowed in any of the event areas. Badges provided at registration are required for entrance into all functions and will be strictly enforced.

LIABILITY & INSURANCEThe Meeting Secretariat and Organisers cannot accept liability for personal accidents or loss of or damage to private property of participants. Participants are advised to take out their own personal travel and health insurance for their trip.

SAFETY & SECURITYPlease do not leave bags or suitcases unattended at any time, whether inside or outside the session halls. Hotels strongly recommend that you use their safety deposit boxes for your valuables.

SMOKING POLICYESPID is a non-smoking Meeting and participants are requested to refrain from smoking in the Meeting Venue.

NO PHOTOGRAPHY DURING SESSION POLICYThe organisers respectfully request participants not to take photographs of slides during sessions. All materials are available via the Meeting Mobile App subject to speakers’ permission.

MOBILE DEVICESPlease turn the sound to silent mode and disable keyboard clicks.

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VENUE FLOOR PLANGROUND LEVEL FIRST LEVEL

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AWARDS

ESPID FELLOWSHIP AWARD 2018-2020

DR JANE ASTRID METZ

Jane is a paediatric registrar specialising in infectious diseases and immunology in Bristol, UK. Her interest is in Streptococcus pneumoniae and factors influencing pneumococcal transmission.

Since graduating from Imperial College, London (MBBS, BSc 1st Class Hons), Jane has focused on becoming a paediatrician working to improve global child health. Her paediatric training in London and Bristol has been complimented by her experience working as a paediatrician for Medecins Sans Frontieres in Liberia and as paediatric clinical research fellow for the University of Oxford in Nepal. She has co-authored papers reporting on Hib immunogenicity, pneumococcal carriage, and paediatric vaccine updates.

She is currently studying for her PhD hoping to advance current knowledge in the relationship between pneumococcal carriage density and transmission.

ESPID FELLOWSHIP AWARD 2018-2020

DR VIRGINIA RAMOS

Virginia Ramos-Martín completed her Specialist Training in Paediatrics in Spain with specialised training in Paediatric Tropical and Infectious Diseases in Barcelona and Panama (2010). She then obtained the MSc in Tropical Paediatrics at The Liverpool School of Tropical Medicine conducting her research project in South-East Africa (Malawi) on the neuro-auditory safety of artemisinin combination treatments for malaria in children (2011). Subsequently, she worked as a paediatrician and delivered training to health officers and doctors in Equatorial Guinea and Liberia.

She continued her training as a clinician-scientist joining the University of Liverpool (Institute of Translational Medicine) and Alder Hey Children´s Hospital (Liverpool, UK) as a clinical research fellow in 2012. Her PhD work (2013-2017) focused on understanding the PK-PD relationships of antimicrobials in neonates and children towards treatment optimization and improved clinical outcomes. She developed in vitro and in vivo models of infection linked with clinical data and PK-PD mathematical modelling to contribute building the evidence on paediatric dosage regimens associated with maximal efficacy and suppression of drug resistance. As part of this work, she completed a training stay in the Laboratory of Applied Pharmacokinetics and Bioinformatics, University of Southern California, where she learnt and applied improved methods of population PK-PD modelling and Bayesian Adaptive Control for individualised therapy. Throughout these years, she combined research, PID clinical and teaching undertakings.

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ESPID-SEQIRUS FELLOWSHIP 2018-2021

DR LILLY VERHAGEN

During her medical studies in The Netherlands, Lilly Verhagen designed herself the research project which would later become her PhD on respiratory infections in Venezuelan children. Following her interest in tropical pediatrics and infectious diseases, she had come across a Venezuelan research group working in indigenous rural areas in her 5th year of medical school. She then developed and planned a series of studies to obtain insight in the influence of host, environmental and genetic factors on the susceptibility for and the diagnosis and treatment of a wide range of respiratory diseases in ethnically different Venezuelan populations. With the personal stipend she obtained in 2009, at the end of her medical studies, she was able to finance her studies from 2009-2011. In 2011, the work of Lilly and others showing high prevalence rates of Streptococcus pneumoniae in isolated populations led to the obtainment of a research grant from Pfizer, manufacturer of pneumococcal conjugate vaccines. With this grant Lilly, together with a team of Dutch and Venezuelan researchers, performed the first study on the impact of vaccination with the 13-valent pneumococcal conjugate vaccine on nasopharyngeal colonization and antibody response in South American indigenous children. Her studies resulted in a PhD, which Lilly received cum laude at April 15, 2014. Furthermore, these studies have resulted in over 20 publications in international peer-reviewed medical journals. Since March 2014, Lilly is working as a pediatric resident in the Wilhelmina Children’s Hospital in Utrecht. She is combining her residency with research projects in Dutch children with recurrent respiratory tract infections, continuing her research focused on pediatric risk groups for respiratory infections.

YOUNG INVESTIGATOR AWARD BASIC RESEARCH

HENRIETTE RUDOLPH

Henriette Rudolph was born in Dresden (Germany) on May 7, 1981. From 2000 to 2007 she studied Medicine at the Ruprecht-Karls-University Heidelberg, where she graduated magna cum laude for her doctoral exam in Immunology. From 2003 to 2004 she studied Medicine at University of Claude Bernard Lyon (France). In 2007, she received her medical degree and started her paediatric training at the University Children’s Hospital Mannheim, Medical Faculty Mannheim, Heidelberg University. Under the supervision of Prof. Dr. Horst Schroten and Prof. Dr. Tobias Tenenbaum she started her research work in the field of Paediatric Infectious Diseases. She focused her work on the pathogenesis of viral meningitis applying different murine and human in vitro models of the Blood-Cerebrospinal-Fluid Barrier and the Blood-Brain Barrier. In 2011, she received a research award from the German Society of Paediatric Infectious Diseases (DGPI) for a clinical study on petechial rash. From 2012 to 2013, a research fellowship award from the DGPI allowed her to stay as post-doctoral fellow at the Theodor-Kocher-Institute Bern (Switzerland) in the department of neuroimmunology. Here, she could extend her knowledge in leukocyte migration in vitro and in vivo in murine models of experimental autoimmune encephalitis. Funded by the Olympia Morata Programme of Heidelberg University for female postdoctoral researchers, she could continue her research projects with a habilitation currently in preparation. From 2016 to 2018, she completed her training in „Paediatric Infectious Diseases Specialist according to a European curriculum“ at the University Children’s Hospital Mannheim. At present she is delegated from Mannheim to the department of stem cell transplantation of the University Children’s Hospital Frankfurt. She participates in several clinical and experimental research projects.

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YOUNG INVESTIGATOR AWARD CLINICAL RESEARCH

NAVIN BOEDDHA

Navin Boeddha (1987), originally from Suriname (South America), obtained his medical degree (2011) from the Erasmus MC, University Medical Center Rotterdam, The Netherlands. He gained clinical experience in general pediatrics at the Maasstad Hospital and in pediatric intensive care at Erasmus MC.

In 2013, he commenced his PhD (supervised by Prof. J.A. Hazelzet, Dr. M. Emonts, and Dr. G.J. Driessen) on severe bacterial infections in children, focusing on several inflammatory, hemostatic, genetic, and environmental factors associated with severity of sepsis. He was member of the EUCLIDS consortium (lead by Prof. M. Levin), evaluating genetic determinants of susceptibility and/or severity in life-threatening bacterial infections of childhood. The PhD thesis defense is planned.

Within ESPID (member from 2013 onwards), he actively participated in courses and workshops, for example the Online Antibiotic Management Course (2015), Research Masterclass 2015, and Walter Marget Educational Workshop 2016 (winner of “Best clinical case presentation”). He acknowledges the Society for improving his clinical and scientific skills.

Since 2017, Navin has been enrolled to the pediatrics residency programme of Erasmus MC-Sophia Children’s hospital (supervised by Prof. M. de Hoog). He aspires to combine clinical activities and research activities in his further career.

In his spare time, Navin becomes happy by travelling and spending time with family and friends. Being a young father, he enjoys seeing his son discovering the world. Also, he loves sports; he warns that starting a conversation on football will keep you busy for at least 20 minutes.

DISTINGUISHED AWARD FOR COMMUNICATION

DR HANNA NOHYNEK

Chief physician of the Infectious Disease Control and Vaccinations Unit, Department of Health Security, National Institute for Health and Welfare THL Helsinki. Finland

Dr Hanna Nohynek is a vaccinologist with special competence in international health and with a strong interest in paediatric infectious diseases -related research and public health. She has been/is grant holder of the Finnish Academy, EU Commission DG Research, DG Sante and Innovative Medicines Initiative as well as Bill and Melinda Gates Foundation and WHO. She serves as reviewer to scientific journals, and several organizations funding research.

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DISTINGUISHED AWARD FOR EDUCATON

PROF CLAIRE-ANNE SIEGRIST

Claire-Anne Siegrist is Professor of Vaccinology and Pediatrics at the University of Geneva (Switzerland), Director of the Center of Vaccinology of the University Hospitals of Geneva, and Director of the WHO Collaborating Center for Vaccine Immunology.

Board certified in paediatrics and infectious disease, she obtained an Advanced Immunology Diploma in 1989 and initiated a new research group recognized since 1996 as a WHO Collaborating Center. She was nominated as Professor at the University of Geneva in 1999. Among numerous distinctions, she received the ESPID Bill Marshall Award in 2005 and the Nessim Abif Global Prize in 2017.

Professor Siegrist serves as an expert on numerous national and international Immunization Advisory Committees. She is the author of the “Vaccine immunology” chapter of the “Vaccine book” (Plotkin and Orenstein) and has contributed to a large number of scientific publications on numerous aspects of vaccinology. She was the Principal Investigator of several vaccine studies, especially during the H1N1/09 influenza and the 2014/2015 Ebola virus outbreak.

Professor Siegrist is a great teacher and a founding member of the Advanced Course in Vaccinology (www.advac.org) and of Infovac (www.infovac.ch). She is the co-inventor of an expert clinical decision support system for immunization catch-up which is the core of the Swiss electronic immunization record (www.myvaccines.ch). The quality and the objectivity of her engagement for the promotion of evidence-based vaccinology is recognized and appreciated worldwide.

BILL MARSHALL AWARD

HERMIONE LYALL

I am a consultant in paediatric infectious diseases and Clinical Director for Children’s Services at Imperial College Healthcare NHS Trust, London. As an infectious diseases paeditrician, I am particularly interested in viral infections and their interactions with their hosts. Prevention of transmission of HIV from mother to infant, and the management of HIV infected children and young people are my main areas of work. I am also interested in other congenital infections (syphilis, toxoplasmosis, CMV etc) and their prevention. I am a member of the steering committee of PENTA (Paediatric European Network for the Treatment of AIDS) and participate in international treatment trials for HIV infected children. I was PI on the PENTA 18 trial (KONCERT), a trial of once versus twice daily Kaletra in children fully suppressed on therapy, www.pentatrials.org/. I am a paediatric author on the British HIV Association guideline for the management of HIV in pregnancy, updated 2018, www.bhiva.org .

I am passionate about training clinicians, and was chair of the ESPID Education Committee from 2013-16. I inaugurated the development of the Tr@inforPedHIV course in 2005, an annual online and residential course for paediatric HIV, www.pentatrials.org/ . This course has so far trained more than 2000 healthcare workers around the world about the detailed management of paediatric HIV. Whilst ESPID Education Committee Chair I led the development of two new ESPID on line course courses for front line healthcare workers on Antibiotic Management and Immunisation.

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INFORMATION FOR PRESENTERSINSTRUCTIONS FOR INVITED SPEAKERS & ORAL ABSTRACT PRESENTERSDATA PRESENTATIONS • Please make sure to check the online programme or Mobile App for your

scheduled presentation date, time, session, and presentation length. Please note your allocated presentation time includes time for questions and discussion.

• Oral Abstract Presenters will have 10 minutes for presentation which include 2-3 minutes for discussion.

• Invited Speakers will have 20, 25 or 30 minutes, depending on the plenary or symposia session. Please note that this time includes a few minutes for discussion.

During the Meeting, all invited speaker and oral presentations will be available to participants via the Mobile App to assist learning and note taking, as well as allow speakers to easily upload their slides for presentation in the halls via the link which has been provided. Thus, by uploading a presentation via the link, the slides will be available for all registered participants via the Mobile App and will be ready for projection in the session hall.

A personalised instructions letter has been sent to oral presenters and invited speakers with information regarding their presentation upload.

We will also make all oral presentations available on the website after the Meeting, subject to the authors' consent.

Guidelines:

• Oral presenters and invited speakers have been requested to provide us with their presentation slides.

• Please note that you will be able to continuously update your presentation, and make any necessary edits and changes up to 2 hours prior to the session via the Speakers’ Ready Stations. The final version you upload will be the one available via the Mobile App and projected in the session hall.

• Please upload a PowerPoint (97/2003) presentation only (PPT), which will be converted automatically into a PDF file for the participant’s view via the Mobile App.

• Please note you do not need to go to the Speaker’s Ready Station or Presentation Technical Support Room if you have uploaded your most updated PPT file 2 hours prior the session.

• In case your presentation includes a movie, audio file or other links that needs to be checked, please make sure to go to the Speaker’s Ready Stations onsite.

• Alternatively, you may supply your own laptop computer (PC or Mac). In such a case, please:

• Confirm that it has a VGA socket for external signal and come to check it in the session hall where your lecture is taking place during the coffee or lunch break prior to your session, at least 2 hours before the start of the session.

• Upload a copy of the presentation via the link provided (the operators in the Technical Support Room will be able to assist in converting Keynote into PowerPoint, if required).

• Note: it is the presenter's responsibility to follow all copyright and fair use guidelines.

• Invited Speakers and Oral presenters are required to use a Disclosure Slide as the second slide of their presentation. The template can be downloaded on the Meeting website.

INSTRUCTIONS FOR E-POSTER PRESENTERS• E-Poster Discussion presenters have each been allocated 7 minutes to present

their E-Poster, which include 2 minutes for discussion at the E-Poster stations. Please make sure to check the online programme or Mobile App for your scheduled presentation date, time, E-Poster Discussion Session and station.

• E-Poster Viewing abstracts will have no specific presentation date and time. The presenter may stand by the E-Poster Viewing screens in order present their E-Poster during breaks.

• Independent E-Poster Presentation presenters have each been allocated 8 minutes to present their E-Poster, which includes 3 minutes for discussion.

E-POSTER VIEWING Poster presentations accepted for the Meeting will be available for viewing as E-Posters, available online and via the Mobile App during and after the Meeting. Electronic Posters or E-Posters are similar to traditional paper posters, but displayed on-site on multiple large LCD television screens. Abstracts selected for E-Poster Viewing will have no specific presentation date and time. Any E-Poster can be viewed on any screen at any time during the Meeting as well as on mobile devices (smartphones. tablets and laptops) via the Meeting Mobile App. These E-Posters platforms allow users to browse by topics, search for specific content and submit questions to the authors. The author of the E-Poster may stand by the E-Poster screens in order present their E-Poster during breaks. Additionally, delegates will be able to email the presenter via the E-Poster system to set up a meeting to discuss the E-Poster. E-Poster screens can be found in the E-Poster Area in the Exhibition Area, please view floor plan for exact location Authors have been encouraged to embed explanatory audio or video presentations with their E-Posters.

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TOPIC E-POSTER STATION

WEDNESDAY, MAY 30, 2018 11:10-12:40E-POSTER DISCUSSION SESSION 01:

Diagnostics STATION 1

E-POSTER DISCUSSION SESSION 02:

Public health and epidemiology STATION 3


Neonatal infection STATION 5


Vaccine implementation and safety STATION 7


Antibiotic stewardship and infection control STATION 9


Community acquired infections: respiratory tract infections STATION 11


Vaccine efficacy and effectiveness STATION 13

THURSDAY, MAY 31, 2018 14:00-15:30E-POSTER DISCUSSION SESSION 08:

Respiratory tract infections STATION 1


Viral infections STATION 3


Global infectious diseases STATION 5


Vaccine development and immunogenicity STATION 7


Severe bacterial infections STATION 9


Epidemiology of community-acquired diseases STATION 11


Antimicrobials: resistance and pharmacology STATION 13

E-POSTER DISCUSSION SESSIONSParallel E-Poster Discussion Presentations will be presented in the E-Poster Area of the Exhibition . These sessions will be taking place on Wednesday, May 30 and Thursday, May 31. All participants are invited to the E-Poster Stations to hear the short presentations and to ask questions. Each E-Poster Discussion Session will be guided by one moderator.

Presenters should be at the E-Poster viewing stations 10 minutes before the start of the E-Poster Discussion Session and remain there until the session has finished. Each presenter has been allocated 7 minutes to present his/her E-Poster, which includes 2 minutes for discussion.

INDEPENDENT E-POSTER PRESENTATION:New to ESPID! Parallel Independent E-Poster Presentations (IEP) will be presented in the E-Poster Area of the Exhibition. These sessions will be taking place on Thursday, May 31st at 16:00-17:00 and Friday, June 1st at 7:00-7:50. All participants are invited to the E-Poster Stations to hear the short presentations and to ask questions. Each IEP will be guided by one moderator. Presenters should be at the E-Poster viewing stations 10 minutes before the start of the Independent E-Poster Presentation Session and remain there until the session has finished.

Each presenter has been allocated 8 minutes to present his/her E-Poster, which includes 3 minutes for discussion.

All digital materials will be made available on the ESPID Meeting website after the Meeting, subject to the authors' consent.

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CME/CPD ACCREDITATIONCOMMITMENT TO THE HIGHEST STANDARDS IN CME/CPDKenes is committed to being a valuable and knowledgeable partner in the design and delivery of educationally strong, independent, transparent, and effective CME/CPD programmes. Kenes is a proud member of the Good CME Practice Group (gCMEp), a member organisation contributing to improving health outcomes by:

• Championing best practice in CME/CPD

• Maintaining and improving standards

• Mentoring and educating

• Working in collaboration with critical stakeholders

Membership in the Good CME Practice Group illustrates Kenes commitment to high standards and knowledgeable partnership with its clients in the design and delivery of medical events.

EDUCATIONAL OBJECTIVES After attending this event, participants should be able to:

• Address individual needs in compliance with their Continuous Professional Development (CPD) plan.

• Discuss the current research projects within ESPID and enhance opportunities for future collaboration between groups of young researchers.

• Discuss the latest developments in paediatric infectious diseases knowledge including microbiology, epidemiology, pathogenesis, diagnosis, management and therapeutics and primary prevention.

• Discuss the latest treatment options of paediatric hepatitis C.

• Define new clinical microbiology approaches for fast and reliable diagnosis of infections in children.

• Identify educational resources, networks and other for exchange of knowledge and learning about paediatric infections.

• Describe diagnostics and treatments of congenital infection.

• Enhance new relationships with colleagues with common interests throughout the world.

TARGET AUDIENCE ESPID 2018 is the global meeting place for clinicians, researchers, residents, and students in the field of paediatric infectious diseases, epidemiology and immunology. Because of the diverse, clinically focused educational offering, participants are able to tailor the curriculum to meet the needs of international clinicians of all levels of experience.

ACCREDITATION STATEMENT AND CREDIT DESIGNATIONEUROPEAN ACCREDITATION COUNCIL FOR CONTINUING MEDICAL EDUCATION (UEMS/EACCME)The 36th Annual Meeting of the European Society for Paediatric Infectious Diseases (ESPID 2018) is accredited by the European Accreditation Council for Continuing Medical Education (EACCME) to provide the following CME activity for medical specialists. The EACCME is an institution of the European Union of Medical Specialists (UEMS): www.uems.netThe 36th Annual Meeting of the European Society for Paediatric Infectious Diseases (ESPID 2018 is designated for a maximum of, or up to, 35 European external CME credits. Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.

AMERICAN MEDICAL ASSOCIATION (AMA)Through an agreement between the European Union of Medical Specialists and the American Medical Association, physicians may convert EACCME credits to an equivalent number of AMA PRA Category 1 Credits™. Information on the process to convert EACCME credit to AMA credit can be found at www.ama-assn.org/go/internationalcme.

ROYAL COLLEGE OF PHYSICIANS AND SURGEONS OF CANADA Live educational activities, occurring outside of Canada, recognized by the UEMS-EACCME for ECMEC credits are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of The Royal College of Physicians and Surgeons of Canada. For more information, visit: www.royalcollege.ca.

CREDIT BREAKDOWN Each participant should claim only those hours of credit that he/she actually spent in the educational activity.

Day Maximum Credits

Monday, May 28, 2018 3

Tuesday, May 29, 2018 6

Wednesday, May 30, 2018 8

Thursday, May 31, 2018 7

Friday, June 1, 2018 4

Saturday, June 2, 2018 7

Total Credits: 35

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TO RECEIVE YOUR CME/CPD CERTIFICATE The CME/CPD certificate will be available after completing the online evaluation and credit claiming procedure. The process takes about 5 minutes. We thank you for your feedback as it is an important part of CME/CPD accreditation and helps improve future educational offerings.

Before June 30th

1. Access the online system via any of the following• Visit https://www.surveymonkey.com/r/ESPID2018Evaluation• Please note that web browsers Mozilla Firefox 2.X or higher, or Google

Chrome are recommended• Visit the CME/CPD Accreditation page on the event website• Follow the link in the email sent at the end of the event

2. Complete the online evaluation and obtain your CME certificate to download and/or print for your files

DISCLOSURE AND RESOLUTION OF PERSONAL CONFLICTS OF INTEREST In accordance with CME/CPD accreditation criteria and standards for commercial support to ensure balance, independence, objectivity, and scientific rigor, those in control of the educational content must disclose potential or actual conflicts of interest. Disclosure information is evaluated and conflicts of interest resolved. Disclosure is made to participants prior to the activity. Participants will be asked on the evaluation to assess the objectivity and independence of the event.

Disclosure information is available on the event website and also posted on the notice board in the registration area.

INDUSTRY SUPPORT DISCLOSURE This event is supported, in part, by funding from industry. All support is managed in strict accordance with CME/CPD accreditation criteria and standards for commercial support. Appropriate acknowledgement of all supporting organisations is made in the programme guide, on the event website, and with signage during the event.

• A list of all industry supporters is available in the Industry Support and Exhibition section at the back of the programme guide.

• Detailed programmes for all Industry Sessions are available on page 46.

OPTIONAL NETWORKING EVENTS PROGRAMME OPENING SYMPOSIUM & WELCOME RECEPTIONTUESDAY, MAY 29, 2018 | 16:45 -19:30 | PLENARY HALL, MEETING CENTRE This year's ESPID Opening Plenary Symposium will be structured as an interactive panel discussion session. The session will be entitled "Protecting medical science in the post-truth era", which will be Chaired by Miriam Frankel. Our expert panel of discussants will include Esther Crawley, Noni MacDonald, Kåre Mølbak, Volker Fingerle, and Mark Lorch. The Symposium will include greetings by the President of ESPID, Chairs of the Local and International Scientific Committees.

The Opening Symposium will be immediately followed by the Welcome Reception in the Exhibition Area. Please join us for the official 36th ESPID Annual Meeting opening.

ESPID ANNUAL MEMBER & INVITED FACULTY DINNER THURSDAY, MAY 31 | 20:00 | QUALITY HOTEL VIEWAddress: Quality Hotel View

Hyllie stationstorg 29

SE-215 32 Malmö

ESPID 2018 Faculty and Members are invited to join us for the ESPID Annual Dinner. We look forward to your participation and your continued support of ESPID. Tickets may be purchased at the Registration Desk – subject to availability

*For ESPID Members and Invited Guests.

NETWORKING DINNER FRIDAY, JUNE 1 | 20:00 | GLASKLARTAddress: Glasklart Event & Restaurang

Dockplatsen 1

211 19 Malmö, Sweden

Meet colleagues and international experts outside the session halls. Don’t miss this great opportunity to mix, mingle and build connections that will last you a lifetime!

Tickets may be purchased at the Registration Desk – subject to availability.

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PROGRAMME AT A GLANCE Sessions marked with a webcast icon will be webcasted and will be available to ESPID Members on the Society website (www.espid.org) after the Meeting.

Sessions marked with a voting icon will include the in-session voting feature. Please use the Mobile App to cast your vote during the sessions.

?Sessions marked with a Ask the speaker icon icon will include the ask the speaker feature. Please use the Mobile App to submit questions to the speakers during the sessions.

Sessions marked with an Evaluation icon will include the evaluation feature. Please use the Mobile App in order to evaluate sessions.

Sessions marked with a Like icon will include the Oral/E-Poster “Like” feature. Please use the Mobile App in order to “Like” the best Oral or E-Poster in the Oral Sessions and E-Poster Discussion Sessions.

ESPID is pleased to continue its refreshed programme format for 2018. Each session will now be easily identified by a specific track. ESPID has ensured that each session's content (lectures, speakers, abstracts and E-Posters) is focused on science, education or both.

SCIENCE TRACK EDUCATIONAL TRACK SCIENCE AND EDUCATIONAL TRACK

SPONSORED SYMPOSIUM BREAKS & NETWORKING EVENT ESPID MEMBER AGM SATELLITE SYMPOSIUM

MONDAY, MAY 28, 2018PRE-MEETING SYMPOSIA

PLENARY HALL HALL C2 (C1+C2) HALL D2 (D1+D2)

13:00-14:30

INDUSTRY SYMPOSIUM 1 HPV VACCINATION OF MALES –THE PEDIATRI-CIAN AS A VITAL PART OF THE SOLUTIONIndustry Session not included in main event CME/CPD credit

WALTER MARGET EDUCATIONAL WORKSHOP(by invitation only)

14:00-19:00Infections in the immunocompro-misedNigel Hall,UKAsgeir Haraldsson, Iceland

14:30-14:45 BREAK WALTER MARGET EDUCATIONAL WORKSHOPBreak-out session

14:45-16:15

INDUSTRY SYMPOSIUM 2PERTUSSIS – EPIDEMIOLOGY, IMMUNOLOGY AND CLINICAL MANIFESTATIONSIndustry Session not included in main event CME/CPD credit

16:15-16:45 COFFEE BREAK IN PLENARY HALL FOYER

16:45-18:15

INDUSTRY SYMPOSIUM 3 PNEUMOCOCCAL CONJUGATE VACCINES: FROM CLINICAL EVIDENCE TO GLOBAL IMPACTIndustry Session not included in main event CME/CPD credit

18:15-18:30 BREAK

18:30-20:00

INDUSTRY SYMPOSIUM 4VACCINEACTIONIndustry Session not included in main event CME/CPD credit

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TUESDAY, MAY 29, 2018PLENARY HALL HALL C2 (C1+C2) HALL D2 (D1 + D2)

6:45-7:45 YOGA CLASS (Free of Charge)

8:30-10:00

INDUSTRY SYMPOSIUM 5 PREVENTION OF INFLUENZA: NEW PROSPECTS FOR YOUNG CHILDRENIndustry Session not included in main event CME/CPD credit

YOUNG ESPID AGM 08:15-09:30

WALTER MARGET EDUCATIONAL WORKSHOP(by invitation only)

09:30- 13:45Infections in the immunocompromisedAnnemarie van Rossum, The NetherlandsNicole Ritz, Switzerland

Break-out session

10:00-10:30 COFFEE BREAK IN THE EXHIBITION AREA

10:30-12:00INDUSTRY SYMPOSIUM 6EXPANDING MENINGOCOCCAL PREVENTION IN EUROPE: REAL-LIFE EXPERIENCEIndustry Session not included in main event CME/CPD credit

12:00-13:00 NETWORKING, LUNCH BREAK IN THE EXHIBITION AREA*

13:00-14:30INDUSTRY SYMPOSIUM 7UNDERSTANDING PROTEIN BASED VACCINES FOR MenB DISEASE PREVENTIONIndustry Session not included in main event CME/CPD credit

14:30-14:45 ICE CREAM BREAK IN THE EXHIBITION AREA

14:45-16:15

ESPID PLENARY SYMPOSIUM 1 NUCLEIC ACID – NEW PERSPECTIVES ON ANTIQUE MECHANISMSChairs: Nigel Curtis, Australia Anja Poulsen, DenmarkThe CRISPR story Marco Herold, Australia Ancient DNA & outbreaks Eske Willerslev, DenmarkSelected abstracts ?

16:15-16:45 COFFEE BREAK IN THE EXHIBITION AREA

16:45-18:15

ESPID OPENING SYMPOSIUM PROTECTING MEDICAL SCIENCE IN THE POST-TRUTH ERAChair: Olof Hertting , SwedenHost: Miriam Frankel, SwedenPanellists: Esther Crawley, UK Noni MacDonald, Canada Kåre Mølbak, Denmark Volker Fingerle, Germany Mark Lorch, UKWelcome Speech by Meeting Co-Chairs ?

18:15-19:30 WELCOME RECEPTION IN THE EXHIBITION AREA

*Prepaid lunch is available in the exhibition area. To purchase lunch on site, visit the cafeteria or cash bar located near the registration desk. The cash bar and cafeteria will be open only during the networking breaks.

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WEDNESDAY, MAY 30, 2018 AMPLENARY HALL HALL A Hall B Hall C2 + D2 Hall E1 Hall E2 ROMEO JULIA HAMLET

06:30-07:30 FUN RUN (Free of Charge)

7:00-7:50

MEET THE PROFESSOR 1 - DISCOURSE WITH VACCINATION DENIERS - AN INTERACTIVE SESSIONKatrine Habersaat

MEET THE PROFESSOR 2 - TEST YOUR VACCINOLOGY KNOWLEDGENoni MacDonald & Hanna NoynekSelected abstracts

MEET THE PROFESSOR 3 - POST-NEONATAL VIRAL AND OTHER CULTURE NEGATIVE INFECTIONS Philippe Henneke & Pinaki PanigrahiSelected abstracts

MEET THE PROFESSOR 4 - PAEDIATRIC ANTIBIOTIC STEWARDSHIP Stefania Vergnano & Fredrik ResmanSelected abstracts

MEET THE PROFESSOR 5 - DIAGNOSTICS AND TREAT-MENTS OF CONGENITAL INFECTIONHermione Lyall & Sing Sing WaySelected abstracts

MEET THE PROFESSOR 6 - FEVER & THE RETURNING TRAVELERShamez Ladhani & Kristina Elfving

MEET THE PROFESSOR 7 - HIV MANAGEMENT DECISIONSPablo Rojo & Oana Falup-PecurariuSelected abstracts

MEET THE PROFESSOR 8 - WHAT THE PID DOCTOR NEEDS TO KNOW ABOUT CHRONIC FATIGUE Esther Crawley

7:50-8:00 SHORT BREAK

8:00-9:30

ESPID PLENARY SYMPOSIUM 2 - 21ST CENTURY MILESTONES IN INFECTIOUS DISEASESChairs: Adam Finn, UK Deborah Frithiof, Sweden Polio eradication Hamid Jafari, USASepsis prevention among infants in rural India Pinaki Panigrahi, USASelected abstracts ?

9:30-10:00 COFFEE BREAK, E-POSTER VIEWING, VISIT THE EXHIBITION

10:00-11:00

ORAL PRESENTATION SESSION 1 - VARICELLA - ZOSTER Chairs: George Syrogiannopou-los, Greece Deborah Frithiof, Sweden ?

ORAL PRESENTATION SESSION 2 - NEONATAL INFECTION(S) Chairs: Oana Falup-Pecurariu, Romania Christian Penno, ?

ORAL PRESENTATION SESSION 3 - FUNGAL INFECTIONS Chairs: Elisa Cooke Marie-Louise von Linstow,

?

ORAL PRESENTATION SESSION 4 - DIAGNOSTICS Chairs: Anne Marie van Rossum, Ulla Hartling

?


11:10-12:40

EXHIBITION AREA

E-POSTER DISCUSSION SESSIONS # 1-7Chairs: Enitan Carroll Paul Heath Andrew Pollard Saul Faust Karina Butler Pierre Smeesters Nigel Curtis

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12:40-13:40 NETWORKING, LUNCH BREAK, E-POSTER VIEWING, VISIT THE EXHIBITION*

13:40-15:10

ESPID SYMPOSIUM 1NEONATAL INFECTIONSChairs: Paul Heath, UK Percy Nilsson Wimar, SwedenThe neonatal immune system Sing Sing Way, USAIs there a role for biomarkers in antibiotic stewardship in neonates suspected of early onset sepsis? Annemarie van Rossum, NetherlandsSelected abstracts

?

MSF/ESPID JOINT SYMPOSIUM - PAEDIATRIC INFECTIONS IN UNSTABLE SETTINGSChairs: Alexandra Kruse, Denmark Kristina Elfving, SwedenOutcomes of African children treated with antiretroviral therapy during the first decade of paediatric HIV care Mar Pujades-Rodriguez, UKAntimicrobial resistance in West Africa Celine Langendorf, France Neonatal infectious outbreaks Julita Gil, LuxembourgSelected abstracts ?

ESPID SYMPOSIUM 3 SEVERE BACTERIAL INFECTIONSChairs: Asgeir Haraldsson, Iceland Olof Hertting , SwedenSevere PVL infections in children Pablo Rojo, SpainSevere non-tuberculous mycobacterial infections Philipp Henneke, GermanySelected abstracts

?

ESPID SYMPOSIUM 4VACCINE UPDATESChairs: Robin Marlow, UK Anna Nilsson, CountryChildhood varicella vaccination - the German experience Anette Siedler, Germany Pneumococcal serotype replacement Shamez Ladhani, UKWhy drug resistance is a global challenge and vaccine resistance is (mostly) not Andrew F. Read, USA

?


15:40-17:10

ESPID SYMPOSIUM 5TICK-BORNE INFECTIONSChairs: Joachim Luthander, Sweden Marko Pokorn, SloveniaBorrelia - diagnostics Volker Fingerle, GermanyTBE – immunisation Helena Hervius Askling, SwedenSelected abstracts

?

ESPID SYMPOSIUM 6TUBERCULOSIS Chairs: Lise Heilmann Jensen, Denmark Maria Tsolia, GreeceTuberculosis in Eastern Europe Anna Turkova, UK TB in Artic and other indige-nous populations Anders Koch, DenmarkSelected abstracts

?

ESCMID/ESPID SYMPOSIUMNOVELTIES IN DIAGNOSTIC MICROBIOLOGY IN PAEDIATRICS Chairs: Pablo Rojo, Spain Mario Poljak, SloveniaNew clinical microbiology approaches for fast and reliable diagnosis of infections in children Katja Seme, SloveniaMicrobiological methods to prevent, control and trace spread of hospital-acquired infections in children Caroline Quach, CanadaSelected abstracts ?

ESWI/ESPID SYMPOSIUM CHILDHOOD IMMUNISATION AGAINST FLU: WHAT ARE THE OPTIONS?Chairs: Adam Finn, UK Ab Osterhaus, The NetherlandsFlu prevention in children, the American approach Jon Abramson, USAFlu prevention in children, the European approach Hanna Nohynek, Finland Selected abstracts

?


17:15-18:00

ESPID DEBATEChair: Andrew Pollard, UK COMPULSORY IMMUNISATION FOR/AGAINST Paolo Bonanni vs. Adam Finn ?

WEDNESDAY, MAY 30, 2018 PMPLENARY HALL HALL A Hall B Hall C2 + D2 Hall E1 Hall E2 ROMEO JULIA HAMLET


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THURSDAY, MAY 31, 2018 AMPLENARY HALL HALL A Hall B Hall C2 + D2 Hall E1 Hall E2 ROMEO JULIA HAMLET

6:30-7:30 YOGA CLASS (Free of Charge)

7:00-7:50

MEET THE PROFESSOR 9 - Discourse with vaccination deniers- An interactive sessionKatrine Habersaat

MEET THE PROFESSOR 10 - Infections indicating immuno-deficiency Johannes Trück & George Syrogiannopoulos

MEET THE PROFESSOR 11 - Pertussis in 2018Ulrich Heininger & Marie Louise von Linstow Selected abstracts

MEET THE PROFESSOR 12 - Viral Hepatitis in the clinicGiuseppi Indolfi & Bjorn FischlerSelected abstracts

MEET THE PROFESSOR 13 - Severe Pneumonia in children Chrissie Jones & Federico Martinón-TorresSelected abstracts

MEET THE PROFESSOR 14 - Otitis media & rational use of antibiotics Fernanda Rodrigues & Ann Hermansson

MEET THE PROFESSOR 15 - Periodic fever Annacarin Horne & Santiago Mintegi

MEET THE PROFESSOR 16 - Tuberculosis management conundrumsAnna Turkova & Nicole Ritz Selected abstracts


8:00-9:30

ESPID SYMPOSIUM 9GLOBAL CHILD HEALTHChairs: Fabian Schumacher, Italy Freddy Karup Pedersen, DenmarkProviding primary care for migrant children in Europe: a European Academy of Paediatrics (EAP) recommendation Nicole Ritz, SwitzerlandInfectious diseases and migration – the example from Sweden from 2015-2016 Ann Lindstrand, SwedenInfections in malnourished children Zulfiqar Bhutta, Pakistan Selected abstracts ?

ESPID SYMPOSIUM 10 HEPATITIS Chairs: Thilde Nordmann Winther, Denmark Delane Shingadia, UKPaediatric hepatitis C - what is the global burden and what are the treatment options today and tomorrow Giuseppi Indolfi, ItalyC the other letters as well - news about hepatitis B and E Björn Fischler, Sweden

?

ESPID SYMPOSIUM 11VACCINES - BEYOND DIRECT EFFECTSChairs: Ulrich Heininger, Switzerland Anja Poulson, DenmarkNon-specific effects of vaccines Nigel Curtis, Australia Revealing the consequences of measles infection and control: from individual immune repertoires to population dynamics Michael Mina, USASelected abstracts

?

ESPID EDUCATIONAL SYMPOSIUM ANTIMICROBIAL THERAPYChairs: Karina Butler, Ireland Ulrika Tinghäll Nilsson, SwedenBreakpoints for the paedi-atrician Christian Giske, SwedenPK/PD modelling versus clinical trials Catherijne Knibbe, Nether-landsStep by step approach: a safe way to identify feverish young infants suitable for outpatient management Santiago Mintegi, Spain

?


10:00-11:30

ORAL PRESENTATION SESSION 5 MODELLING AND VACCINE EFFICACYChairs: Chrissie Jones, UK Percy Nilsson Wimar

?

ORAL PRESENTATION SESSION 6 PUBLIC HEALTH AND EPIDE-MIOLOGYChairs: Pierre Smeesters Lise Heilmann Jensen

?

ORAL PRESENTATION SESSION 7 IMMUNOLOGY AND HOST-PATH-OGEN INTERACTIONSChairs: Ronald De Groot Olof Hertting

?

ORAL PRESENTATION SESSION 8 VACCINE IMPLEMENTATION AND SAFETY Chairs: Ron Dagan, Israel Marie Louise von Linstow ?

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11:30-12:30

BEST OF ESPID - Chairs: Pierre Smeesters, Belgium Adam Finn, UKEducation Award: Claire-Anne Siegrist Communication Award: Hanna Nohynek

12:30-13:00

BILL MARSHALL LECTURE & AWARD - Lessons from HIV - can we eradicate congenital CMV? Hermione Lyall, UK

13:00-14:00 NETWORKING, LUNCH BREAK, E-POSTER VIEWING , VISIT THE EXHIBITION*

14:00-15:30

EXHIBITION AREA RESEARCH SESSION 1 RESEARCH SESSION 2 RESEARCH SESSION 3

E-POSTER DISCUSSION SESSIONS #8-14 Chairs: Ron Dagan Ulrich Heininger Terho Heikkinen Ronald De Groot Pierre Van Damme Federico Martinon-Torres Maria Tsolia


16:00-17:00

EXHIBITION AREA

INDEPENDENT E-POSTER PRESENTATIONS E-poster booking time

17:00-18:30 AGM MEETING

20:00 ESPID DINNER (held at the Quality Hotel View)

THURSDAY, MAY 31, 2018 PMPLENARY HALL HALL A Hall B Hall C2 + D2 Hall E1 Hall E2 ROMEO JULIA HAMLET


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FRIDAY, JUNE 1, 2018PLENARY HALL HALL A HALL B Hall C2 + D2 Julia+Romeo

06:30-07:30 FUN RUN (Free of Charge)

7:00-7:50EXHIBITION AREA

INDEPENDENT E-POSTER PRESENTATIONS

8:00-9:30

PIDS/ESPID PLENARY SYMPOSIUM 3 -MICROBIOMICS AND IMMUNOLOGY Chairs: Buddy Creech, USA Fernanda Rodrigues, PortugalNeonatal microbiome and immunology Barbara Warner, USAGut microbiota: Agent provocateur in chronic inflammatory diseases Benoit Chassaing, USASelected abstracts ?


10:00-11:30

ORAL PRESENTATION SESSION 9 - VACCINE DEVELOPMENT AND IMMUNOGENICITYChairs: Hermione Lyall, Vana Spoulou, Greece ?

ORAL PRESENTATION SESSION 10 - GLOBAL INFECTIOUS DISEASESChairs: Shai Askenazi Alexandra Kruse ?

ORAL PRESENTATION SESSION 11 - PUBLIC HEALTH AND EPIDEMIOLOGYChairs: Jesus Saavedra, Spain Maria Mossberg ?

ORAL PRESENTATION SESSION 12 - HIVChairs: Emmanouil Galanakis, Greece Theo Zaoutis, USA ?


11:40-13:10

ESPIDINTERACTIVE CASE SESSION - Adam FinnNigel Curtis

?

ESPID SYMPOSIUM 13INFECTION ASSOCIATED WITH INFLAMMATIONChairs: Saul Faust, UK Maria Mossberg, SwedenKawasaki disease Paul Brogan, UKTreatment of HLH Annacarin Horne, SwedenSelected abstracts

?

ESPID SYMPOSIUM 14INFECTIONS IN THE IMMUNOCOMPROMISED CHILDChairs: Johannes Truck, Switzerland Mette Holm, Denmark Treatment of candidiasis and aspergillosis Adilia Warris, UKClinical considerations in the hematopoietic stem cell transplant management of primary immunodeficiencies Andrew Gennery, UKSelected abstracts ?

WHO/ECDC/ESPID SYMPOSIUM -REFINING VACCINE PROGRAMSChairs: Pierre van Damme, Belgium Charlotta Webb, SwedenFalse vaccine contraindications Federico Martinón-Torres, SpainAnxiety related events Oleg Benes, DenmarkVaccine shortages Tarik Derrough, Sweden ?

13:10-14:00 NETWORKING, LUNCH BREAK, E-POSTER VIEWING , VISIT THE EXHIBITION*

POST-MEETING SYMPOSIA

14:00-15:30INDUSTRY SYMPOSIUM 8 - DIFFERENT STRATEGIES - ONE GOAL: TO TURN VACCINES INTO VACCINATIONIndustry Session not included in main event CME/CPD credit


15:45-17:15SPECIAL SATELLITE SYMPOSIUM organised by SSI and Danish & Swedish PID Societies THE EVOLVING MEASLES CRISIS IN EUROPE

20: 00 NETWORKING EVENT (held at the Glasklart) *Prepaid lunch is available in the exhibition area. To purchase lunch on site, visit the cafeteria or cash bar located near the

registration desk. The cash bar and cafeteria will be open only during the networking breaks.

42

SATURDAY, JUNE 2, 2018Quality Hotel (OFFSITE)

08:30-18:15 ESPID RESEARCH MASTERCLASS (LUNCH INCLUDED)

RECOGNITION, ACKNOWLEDGMENTS & INDUSTRY SUPPORT

36TH ANNUAL MEETING OF THE

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ACKNOWLEDGMENTSThe Organising Committee and the Board of ESPID would like to express gratitude and acknowledge the following companies for their generous support of the 36th Annual Meeting of the European Society for Paediatric Infectious Diseases (ESPID), organised jointly by the ESPID and the ESPID Foundation.

PLATINUM SUPPORTERS

BRONZE SUPPORTER

SUPPORTERS

EXHIBITORS

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PRE-MEETING INDUSTRY SUPPORTED SYMPOSIAMONDAY, MAY 28, 2018

13:00 – 14:30 PLENARY HALL

HPV VACCINATION OF MALES –THE PEDIATRICIAN AS A VITAL PART OF THE SOLUTION

Symposium Organized by

CHAIR: Kenneth Alexander, USA

13:00 INTRODUCTION & OPENING REMARKS Kenneth Alexander, Nemours Children’s Hospital, Orlando, Florida, USA

13:10 HPV CANCERS AND DISEASE IN MALES Xavier Bosch, Catalan Institute of Oncology, Barcelona, Spain

13:30 RATIONALE FOR INCLUSION OF MALES IN NATIONAL IMMUNIZATION PROGRAMS Paolo Bonanni, University of Florence, Italy

13:50 REAL WORLD ISSUES IN CLINICAL PRACTICE: THE ROLE OF THE PEDIATRICIAN TO VACCINATE BOYS AND GIRLS Kenneth Alexander, Nemours Children’s Hospital, Orlando, Florida, USA

14:10 Q&A PANEL DISCUSSION All

14:45-16:15 PLENARY HALL

PERTUSSIS – EPIDEMIOLOGY, IMMUNOLOGY AND CLINICAL MANIFESTATIONS

The timeslot of this Pre- Meeting Symposium has been offered by Sanofi Pasteur to Karolinska institutet and The Public Health Agency of Sweden. Agenda and content of presentations have been developed independently by Karolinska institutet and The Public Health Agency of Sweden, with no input from Sanofi Pasteur

Host: Christian Penno, Sweden

14.45 INTRODUCTION

14.50 20 YEARS OF ENHANCED PERTUSSIS SURVEILLANCE IN SWEDEN Bernice Aronsson, The Public Health Agency of Sweden

15.10 MATERNAL PERTUSSIS VACCINATION IN 2018 Pierre van Damme, Centre for the Evaluation of Vaccination, Antwerp University

15.30 IMMUNE RESPONSES TO BORDETELLA PERTUSSIS INFECTION AND VACCINATION Giorgio Fedele, Istituto Superiore di Sanità, Rome

15.50 SEVERE PERTUSSIS IN INFANTS - CLINICAL MANIFESTATION AND MOLECULAR CHARACTERIZATION Alberto Villani, Ospedale Pediatrico Bambino Gesù, Rome

16.10 SUMMARY

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PNEUMOCOCCAL CONJUGATE VACCINES: FROM CLINICAL EVIDENCE TO GLOBAL IMPACT


CHAIR: Prof. Thomas Benfield, DENMARK CO-CHAIR: Prof. Heinz-Josef Schmitt, FRANCE

16:45 WELCOME AND INTRODUCTION Prof. Heinz-Josef Schmitt, Pfizer, Paris, France

16:50 PCVS* – THE NORDIC EXPERIENCE Prof. Thomas Benfield, University of Copenhagen and Hvidovre Hospital, Denmark

17:00 A REVIEW OF GLOBAL PCV IMPACT Dr. Carla Vizzoti, Centre for the Control and Prevention of Communicable Diseases, Isalud University, Buenos Aires, Argentina

17:25 DID PCV DELIVER UP TO OUR EXPECTATIONS? THE ISRAEL PARADIGM Prof. Ron Dagan, Ben-Gurion University of the Negev, Beer-Sheva, Israel

18:00 Q&A All

18:15 Close

*PCV: pneumococcal polysaccharide conjugate vaccine


VACCINEACTIONSymposium Organized by

CHAIR: Prof. Federico Martinon-Torres, Spain

18:30 WELCOME & INTRODUCTION Prof. Federico Martinon-Torres, Santiago Clinic Hospital, Santiago de Compostela, Spain

18:40 MEASLES IN EUROPE: WHAT NEEDS TO BE DONE? Prof.Pier Luigi Lopalco, University of Pisa, Italy

18:50 THE ROLE OF SOCIAL MEDIA AND HEALTH CARE PRACTITIONERS IN VACCINE CONFIDENCE Prof. Roberto Burioni, Vita-Salute San Raffaele University, Milano, Italy

19:05 ARE WE MISSING AN OPPORTUNITY? ROTAVIRUS AND VARICELLA VACCINATION IN EUROPE Prof. Federico Martinon-Torres, Santiago Clinic Hospital; Santiago de Compostela, Spain

19:20 OPTIMIZING HEXAVALENT VACCINATION IN EUROPE Prof. Carl Heinz Wirsing von König, University of Dusseldorf, Germany

19:40 FROM SEEDS TO ARMS: MANAGING VACCINES PRODUCTION COMPLEXITY Prof. Pierre Van Damme, University of Antwerp, Wilrijk, Belgium

19:50 Q&A All

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TUESDAY, MAY 29, 2018

08:30-10:00 PLENARY HALL PREVENTION OF INFLUENZA: NEW PROSPECTS FOR YOUNG CHILDREN


CHAIR: Prof. Terho Heikkinen, Finland

08:30 INTRODUCTION

08:35 INFLUENZA AND INFLUENZA VACCINATION IN CHILDREN Prof. Terho Heikkinen, Professor of Pediatrics, University of Turku, Turku, Finland

09:00 RATIONALE FOR DEVELOPMENT OF QUADRIVALENT INFLUENZA VACCINES Dr. Jan Kyncl, Head, Department of Infectious Diseases Epidemiology, National Institute of Public Health, Prague, Czech Republic

09:25 THE SANOFI PASTEUR QUADRIVALENT INFLUENZA VACCINE EFFICACY STUDY IN CHILDREN FROM 6 TO 35 MONTHS Dr. Rosalind Hollingsworth, Global Medical Expert Lead, Influenza, Sanofi Pasteur, Swiftwater, USA

09:50 Q&A All

10:30 – 12:00 PLENARY HALLEXPANDING MENINGOCOCCAL PREVENTION IN EUROPE: REAL-LIFE EXPERIENCE


CHAIR: Dr. Rafik Bekkat-Berkani, USA

10:30 WELCOME AND INTRODUCTION Dr Rafik Bekkat-Berkani, Lead, Global Medical Affairs Neisseria, GSK Vaccines, USA

10:35 MENINGOCOCCAL VACCINES: FROM DISCOVERY TO PRACTICE Prof. Angelika Banzhoff, Director, Global Medical Affairs Neisseria, GSK Vaccines, Germany

10:55 EVOLUTION OF MENINGOCOCCAL VACCINATION OFFERED IN ITALY Prof. Pier Luigi Lopalco, Full Professor of Hygiene and Preventive Medicine, University of Pisa, Italy

11:15 NATIONAL IMMUNISATION PROGRAMME AGAINST MENINGOCOCCAL DISEASES: THE UK MODEL Dr. Nelly Ninis, Consultant in general paediatrics, St Mary’s Hospital, UK

11:35 DISCUSSION AND Q&A All

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13:00 – 14:30 PLENARY HALLUNDERSTANDING PROTEIN BASED VACCINES FOR MenB DISEASE PREVENTION


CHAIR: Prof. Ray Borrow, UK & Dr. Jamie Findlow, UK

13:00 INTRODUCTORY COMMENTS Dr. Jamie Findlow, Medical and Scientific Affairs, International Developed Markets, Pfizer Vaccines, UK & Prof Ray Borrow, Public Health England, UK

13:05 MENINGOCOCCAL DISEASE; A DEVASTATING AND EVER-PRESENT FOE Prof. Marco Safadi, Santa Casa de São Paulo School of Medical Sciences, Brazil

13:30 MENINGOCOCCAL VACCINES; ADVANCES IN DISEASE PREVENTION Prof. Ray Borrow, Public Health England, UK

13:50 VACCINES TARGETING MenB Prof. Saul Faust, University of Southampton Director, Southampton NIHR Wellcome Trust Clinical Research Facility, UK

14:20 PODIUM DISCUSSION AND SUMMARY All

14:00-15:30 PLENARY HALLDIFFERENT STRATEGIES - ONE GOAL: TO TURN VACCINES INTO VACCINATION


CO-CHAIR: Prof. Susanna Esposito, Italy & Dr. Thomas Breuer, Belgium

14:00 WELCOME AND INTRODUCTION Prof. Susanna Esposito, Italy & Dr. Thomas Breuer

14:10 IMPACT OF PNEUMOCOCCAL VACCINES IN A HIGH COVERAGE SETTING Prof. Sven-Arne Silfverdal, Chief Medical Officer, Child Health Care Unit, Västerbotten County Council, Sweden

14:30 MEASLES AND VARICELLA: IS THIS THE TIME TO RETHINK VACCINATION STRATEGIES? Dr. Hanna Nohynek, Chief Physician, Infectious Disease Control & Vaccinations Unit, National Institute for Health and Welfare, THL, Finland

14:50 COVERAGE IN VULNERABLE POPULATIONS – PERTUSSIS PREVENTION IN PRETERMS AND NEWBORNS TOO YOUNG TO BE VACCINATED Prof. Susanna Esposito, Director, Pediatric Section & Pediatric Clinic of the Hospital of Perugia, Italy & Prof. David Salisbury, Fellow of the Academy of Medical Sciences and Associate Fellow at the Centre on Global Health Security, Chatham House, UK

15:10 CONCLUDING REMARKS AND ROUND-TABLE DISCUSSION, WITH QUESTIONS FROM THE AUDIENCE All

FRIDAY, JUNE 1, 2018

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SPECIAL SATELLITE SYMPOSIUMFRIDAY, JUNE 1, 2018

15:45-17:15 PLENARY HALL

THE EVOLVING MEASLES CRISIS IN EUROPE

15.45 INTRODUCTION (Peter Henrik Andersen, SSI, Denmark)

16.00 MEASLES ELIMINATION IN EUROPE – HOW CLOSE ARE WE AND WHAT ARE THE CHALLENGES? (Mark Muscat, WHO, Europe)

16.20 COMPLICATIONS AFTER MEASLES. WHAT CAN EU SURVEILLANCE DATA TELL US? (Emmanuel Robesyn, ECDC)

16.35 TRANSMISSION IN HEALTH CARE SETTINGS – AND THE ROLE OF HEALTH CARE PERSONNEL (Ann Lindstrand, Public Health Agency in Sweden)

16.50 PROTECTING THE MOST VULNERABLE – INFANTS AND IMMUNOCOMPROMISED CHILDREN (Freddy Karup Pedersen, Denmark)

17.05 GENERAL (PANEL) DISCUSSION

EXHIBITION

LIST OF EXHIBITORS

AJ Vaccines 15

Becton Dickinson 05

BioMerieux 12

Cepheid (Danaher) 07

European Society for Paediatric Infectious Diseases

02

GlaxoSmithKline 03

Hibergene 10

Luminex 08

Meridian Bioscience 13

MCM 16

MSD 01

Pediatric Infectious Diseases Society

14

Pfizer 04

Sanofi Pasteur 06

VACCINE REMINDER 11

Wisepress Medical Bookshop

09

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