malignant neoplasia... 2nd lab
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Neoplasia 4….By shin n KavitaPics frm David Santos
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AMYLOID DEPOSITS DISEASE : AMYLOID , THYROID
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Disease : Basal cell CACharacteristic appearance : Picket fence appearance
Cells at pointer : Palisade of Basal cells
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Disease : Squamous cell CA
Epidermis that invaded the dermis.. Squamous cells arranged into lobules
Keratinization in the centers .. Known as keratin pearls
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Disease : tumor emboli, lung
Shows hematogenous spread.. The malignant cells will be found w/I the BV.
Landmark : normal alveoli
Blood vessel
Malignant cells occluding the BV
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Hematogenous spread in Liver - Gross
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Hair follicle
Sebaceous gland
Dermoid cyst , ovary
There’s ectodermal differentiation due to presence of totipotential cell thus presenting with sebaceous gland, hair follicles, etc.See stuff that are not suppose to be seen in ovary!
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Hair, teeth and sebaceous fluid seen in ovary
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Normal thyroid follicle
The thyroid follicles are surrounded by malignant cells … they are arranged into papillary pattern.
Psammoma’s body
Papillary CA, thyroid Lymphoid spread
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Papillary CA, thyroid Lymphoid spread
Orphan Annie nuclei appearance under HPO
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Thyroid follicle
Infiltration of Leukocytes
Appears like Lymph nodeBut actually , it’s a thyroid gland with autoimmune disease known as Hashimoto’s thyroiditis
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Thyroid hyperplasia
Grave’s Disease
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Ducts invading the stroma so there is reduced amount of stroma..This is due to abnormality of ductal lining cell..
Invasive Ductal carcinoma
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Pleomorphism of cell and nucleus
Hyperchromatic nucleus
Elongated duct
Rectal Adenocarcinoma
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Chorionic villi with hydropic degeneration
Hydatidiform mole (partial mole)
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Hydatidiform mole – Gross…Appears like fish egg… WTF??? Does it???
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Good Luck!!!!!
Thnk u!!!!!!!!!!!!