Macronutrients Carbohydrates. Inorganic vs. Organic Molecules Inorganic: Molecules that are not...
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Transcript of Macronutrients Carbohydrates. Inorganic vs. Organic Molecules Inorganic: Molecules that are not...
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Macronutrients
Carbohydrates
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Inorganic vs. Organic Inorganic vs. Organic MoleculesMolecules
Inorganic: Molecules that are not organic
Are generally simple and are not normally found in living things
Organic compounds: Always contain CARBON and HYDROGENCan contain oxygen, nitrogen, phosphorus, or sulfur
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Macronutrients vs. Macronutrients vs. MicronutrientsMicronutrients
What are the three nutrients that give you energy?
These three nutrients are called MACROnutrients Your body needs a significant amount
of these nutrients MICROnutrients
Your body still needs these nutrients, but in smaller amounts
MICROnutrients do not provide energy
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ESSENTIAL NUTRIENTSESSENTIAL NUTRIENTS
Both macronutrients AND micronutrients are essential: meaning, your body needs them to function properly
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Organic Molecules: Basic Organic Molecules: Basic StructureStructure
What they are made of and how they are put together.
All the macronutrients we study in Nutrition have the same BASICS of structure Are all organic (contain CARBON, HYDROGEN)
Are made up of one type of unit repeated many times (except lipids)
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Macronutrients: Basic Macronutrients: Basic StructureStructure
Single unit is called the MONOmer“Mono” means “one”
Many monomers linked together makes a POLYmer“Poly” means “many”
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In other words…In other words…
Each MONOMER is BUILDING BLOCK in the structure of a POLYMERExample: each brick in a brick
house is a monomer. The house is the polymer.
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CarbohydrateCarbohydratess
Carbohydrates are an essential MACROnutrient: your body needs a lot of carbohydrates to function
Carbohydrates are organic: they contain Carbon, Oxygen, and Hydrogen “Carbo” = Carbon “Hydrate” = water = H2O
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Naming carbohydrates:
The GENERAL name for the MONOMER of carbohydrates is MONOSACCHARIDE Mono = “one” and “saccharide” =
sugar The GENERAL name for the POLYMER
of carbohydrates is POLYSACCHARIDE Poly = “many” and “saccharide” =
sugar
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Naming Carbohydrates Cont…
Carbohydrates are recognizable by their
-ose endings
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Your mission:Your mission:
To discover the common
MONOMER of carbohydrates!
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Discovery of the common monomer
Enzymes are specialized proteins that catalyze chemical reactions
In the simulated activity, an enzyme (specifically, lactASE) catalyzed the reaction that breaks down lactose, the sugar in milk
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You are performing an experiment and get the following results. What
happened? Explain these results in terms of monomers and polymers.
Substance Glucose Test
Water Negative
Milk Negative
Milk + enzyme Positive
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Monomer? Polymer? We were working with two sugars, lactose and
glucose, trying to figure out which was which When lactose was broken down, glucose is
now present Lactose + enzyme glucose +
galactose Polymer + enzyme monomer +
monomer Look at the other way:
Monomer + monomer polymer Glucose + galactose lactose
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Disaccharides & Polysaccharides
Disaccharides consist of two monosaccharides bonded together Monosaccharide + Monosaccharide = Disaccharide 1 + 1 = 2
Polysaccharides consist of MANY monosaccharides and/or disaccharides bonded together Mono + mono + di + di ++++++++ = poly 1 + 1 + 1 +++++++ = 100 – 1,000’s
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Further Classifying Carbohydrates
Monosaccharides and disaccharides are SIMPLE sugars
Polysaccharides, which are made of MANY simple sugars linked together, are called COMPLEX carbohydrates
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Specific examples of carbohydrates
Monosaccharides Examples: glucose (C6H12O6), fructose, and galactose
Disaccharides Examples: sucrose, lactose, and maltose
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Specific examples of Specific examples of CarbohydratesCarbohydrates
Polysaccharides Examples: starch, pectin, cellulose, and glycogen
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General Functions of Carbohydrates
Preferred source of energy for red blood cells, parts of the brain, & nervous system
If the carb is going to provide energy to drive other processes, what must happen?
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Aerobic Cellular Respiration
General definition: The process by which cells transforms
energy (Glucose) into a usable form (ATP) Is a series of three reactions:
1. Glycolysis2. Krebs Cycle3. Electron Transport Chain
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Aerobic Cellular Respiration - General
Cellular respiration is the name for a series of reactions in which glucose is broken down into CO2, H20; ATP is “produced”
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Essential Info
Structure and function of ATP
Cell and mitochondrial structure
Electron carriers
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ATPATP Adenosine
tri-phosphate
Can be easily transformed to ADP (releasing energy) and back to ATP, making it an effective molecule for this process
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ATP/ADP Cycle
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Electron Carriers - Coenzymes
Non-protein molecules that assist enzymes in biochemical reactions; carry electrons and hydrogen ions from one reaction to another
NAD+ NADH (“carrying”)FAD FADH2 (“carrying”)
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Bio Review: Cytosol
The fluid portion of the cell’s cytoplasm
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Mitochondrial StructureMitochondrial Structure
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Mitochondrial Structure
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Glycolysis - General
Takes place in cytosol of the cell
Breaks down 6C glucose molecules into 3C pyruvic acid (pyruvate) molecules
Produces a net gain of 2 molecules of ATP (form of energy we can use), and 2 molecules of NADH
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Between glycolysis and the Krebs Cycle…
3C pyruvic acid from glycolysis enters the mitochondria where additional steps prepare it to enter the Krebs cycle
1. Hydrogen atoms are stripped from pyruvic acid and transferred to NAD+
2. Carbon atom is stripped and lost as carbon dioxide
The now 2C compound bonds to the carrier, CoA now acetyl CoA (acetic acid)
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Pyruvic Acid Becomes Acetyl CoA
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Step 2: Krebs Cycle (also called Citric Acid Cycle):
Mitochondrial Matrix 3C pyruvic acid from glycolysis loses a
carbon molecule and becomes a 2C molecule called acetyl CoA
Acetyl CoA enters the Krebs Cycle Bonds with a 4C compound oxaloacetate
becoming 6C Citric Acid During a series of steps, produces ATP, H
ions, and electrons carried by NAD+ (now NADH) and FAD (now FADH2)
Carbon dioxide as waste
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Pyruvic acid goes to the Krebs Cycle
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The Electron Transport System -
Inner Membrane Electrons from glycolysis and the
Krebs cycle enter the ETC As the electrons move across a
series of complexes in the membrane, hydrogen ions are pumped across the inner membrane (from matrix intermembrane space)
At the end of the “chain” the electrons bond with hydrogen atoms & oxygen to form water
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Anaerobic Respiration
If no oxygen is available, aerobic respiration can’t happen – no final electron acceptor
In anaerobic conditions, only glycolysis can take place – and this is called anaerobic respiration or lactic acid fermentation We will come back to this process
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Summary: Step 3, the ETC Electrons from glycolysis and the Krebs cycle
(carried by NAD+ and FAD) “fall” down a chain of complexes in the mitochondrial membrane
The energy from the electrons “falling” pumps H+ from inside the membrane to outside
Electrons and hydrogen combine with oxygen located at the bottom of the chain and form water (H20)
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With the ETC…
On one side of the membrane is now an accumulation of hydrogen ions (H+)
The human body wants to be at equilibrium After the ETC, there is a high imbalance of +
charges (b/c of H+) one side of a membrane (this is called a proton gradient)
The H+ ions “want” to diffuse back to the other side of the membrane and “even out” but the 2nd mitochondrial membrane is preventing that
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Chemiosmosis
Embedded in the membrane is an enzyme called ATP synthase
H+ ions flow through the ATP synthase to “even out” the charges on both sides of the membrane
As H+ ions flow through, their energy is used to make ATP from ADP and a P
This process is called chemiosmosis
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The ETS / Chemiosmosis
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ETS / Chemiosmosis- View #2
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AnimationsAnimations
Electron transport: http://www.sp.uconn.edu/~terry/images/anim/ETS.html
Proton gradients and chemiosmosis: http://www.sp.uconn.edu/~terry/images/anim/ATPmito.html
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Summary/Overview
Step 1: Glycolysis Step 2: Krebs cycle Step 3: Electron transport system/chemiosmosis
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Cellular Respiration
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Overall Overall equationequation
??Glucose + oxygen ATP + water + carbon dioxide
Reactants: C6H1206, O2
Products: ATP, H20, CO2