- ;m| J ;ub ;7 bo Jbl t- om t- oul - zPREDICTA · N uolo|;v v; t= Jou]-mb - om o= l t r t; 1; t t |...

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Transcript of - ;m| J ;ub ;7 bo Jbl t- om t- oul - zPREDICTA · N uolo|;v v; t= Jou]-mb - om o= l t r t; 1; t t |...

Page 1: - ;m| J ;ub ;7 bo Jbl t- om t- oul - zPREDICTA · N uolo|;v v; t= Jou]-mb - om o= l t r t; 1; t t | r;v bm|o v|u 1| u- t mb|v lblb1hbm] bm b o vv ; N m1ourou-|;v ou]-m Jvr;1bC1 ;

®Paent-Derived 3D Bio-Simulaon Plaorm1-to-1 reconstrucon of human ssues

Simulates disease-specific human organ environment

Correct ssue environment

Non-physiological environment

Hematopoeic compartment Stromal compartment

Preserves heterogeneity of primary ssue

Non small-cell lung cancer

Glioblastoma mulforme

Hematological malignancies

FeaturesPaent-Derived• Mirrors clinical response to therapeucs • Mimics the biology of human cancer in vitro• Maintains long-term survival (>30 d (>30 days) of primary tumor specimens

Mulcellular• Supports proliferaon of tumor, stromal, and immune compartments• Retains heterogeneity of the nave primary ssue ssue • Preserves crical tumor-tumor and tumor-stroma interacons

Nave 3D Architecture• Promotes self-organizaon of mulple cell types into structural units mimicking in vivo ssue • Incorporates organ-specific extracellular matrix and disease-specific soluble factors

cell survival

cell death

live/dead

Epithelialorganoids

Stromal outgrowth viable cells

[email protected] www.zPREDICTA.com/Products/ Patent pending. For Research Use Only: not intended for diagnostic or therapeutic use. ©2017: zPREDICTA