Lonitab (Minoxidil Tablets)

Minoxidil Tablets

Clearsky Pharmacy

Lonitab (Minoxidil Tablets) is used with other medications to treat high blood pressure (hypertension) that is symptomatic or associated with target organ damage and is not manageable with maximum therapeutic doses of a diuretic plus two other antihypertensive medicines.

Lonitab Tablets

Clearsky Pharmacy

Lonitab Tablets are manufactured by Intas Pharmaceuticals Ltd. (Website: www.intaspharma.com)

Minoxidil Tablets Brand Names

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Minoxidil tablets are available as Loniten, Lonitab and Dilminox .

Active Ingredient

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The active ingredient contained in Lonitab tablets is Minoxidil. Each Lonitab Tablets contains 5 mg or 10 mg of Minoxidil.

Chemical Structure

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The structure of Minoxidil is given below:

Uses of Lonitab Tablets

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Lonitab (Minoxidil Tablets) is used with other drugs to treat high blood pressure (hypertension)that is symptomatic or associated with target organ damage and is not manageable with maximum therapeutic doses of a diuretic plus two other antihypertensive medicines. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Minoxidil works by relaxing blood vessels so blood can flow more easily.

Storage Instructions

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Lonitab (Minoxidil Tablets) have to be stored at controlled room temperature i.e. 25C (77F) away from moisture. Keep this as well as all other medicines away from children and pets.

Warnings

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Lonitab (Minoxidil Tablets) can cause a significant retention of salt and water, producing dependent oedema; puffiness of face, eyes or hands, neck vein distention, hepatojugular reflux. Reflex tachycardia and possibly angina pectoris can develop in patients with unsuspected coronary artery disease, unless protected against Lonitab-induced tachycardia with beta-adrenergic blocking drugs or other suitable sympathetic nervous system suppressants. The blood pressure lowering effect of Lonitab is additive to concurrent antihypertensive agents. The interaction of Lonitab with agents that produce orthostatic hypotension may result in excessive blood pressure reduction.Lonitab is not recommended for the treatment of patients with labile or mild hypertension.

Warnings

Clearsky Pharmacy

In patients having condition of pulmonary hypertension associated with mitral valve regurgitation, caution is necessary to avoid excessive tachycardia.This drug must not be used for extended therapy in hypertension readily ameliorated by surgery.Elongation, thickening and enhanced pigmentation of fine body hair (hypertrichosis), unassociated with endocrine abnormalities, is seen in most patients.Approximately 60% of patients exhibit ECG alterations in the direction and magnitude of their T-waves immediately after starting therapy with this medicine.There have been multiple reports of pericarditis occurring in association with this medication.Patients who have had a myocardial infarction should be only treated with Lonitab after a stable post-infarction state has been established.

Lonitab Dosage

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The recommended initial daily Adult dosage is 5 mg given in two divided doses. Daily dosage can be increased to 10, 20 and then to 40 mg per day in divided doses, at 3 day intervals or longer, if required for optimum blood pressure control. The effective dosage range is usually 10 to 40 mg per day.

The dosage of Lonitab tablets (Minoxidil) is given below:

Lonitab Tablets

Clearsky Pharmacy

Contraindications

Lonitab is contraindicated in patients with a hypersensitivity to Minoxidil or any other component of this medication. It is also contraindicated in patients with pheochromocytoma, in pulmonary hypertension associated with mitral stenosis and in patients with severe hepatic impairment.

Minoxidil Tablets Side Effects

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The common side effects of Lonitab (Minoxidil Tablets) with an incidence rate of 1% or more can include Temporary edema, tachycardia, Pericarditis, Pericardial effusion, cardiac tamponade; angina pectoris, Gastro-intestinal Disorders, Fluid retention, Hypertrichosis and Hair changes.

Lonitab Overdose

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There have been only a few cases of deliberate or accidental overdosage with Lonitab (Minoxidil). When exaggerated hypotension is observed in such cases, it is usually likely to occur in association with residual sympathetic nervous system blockade from previous therapy.

Minoxidil Tablets Overdose

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The recommended Minoxidil overdose treatment is intravenous administration of normal saline. Phenylephrine, angiotensin II, vasopressin and dopamine, which reverse the effects of Lonitab (Minoxidil Tablets), should only be used if inadequate perfusion of a vital organ is evident

Minoxidil During Pregnancy

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Lonitab (Minoxidil Tablets) has been classified by the US FDA as Pregnancy Category C. Controlled studies in animals have not revealed evidence of teratogenicity, but reduced conception rates and an increased incidence of fetal absorption have been observed in rabbits given 5 times the usual human dose. Minoxidil tablets are only recommended for use during pregnancy in case there are no alternatives and benefit outweighs risk.

Lonitab Tablets

For more details on Lonitab Tablets click here

Clearsky Pharmacy

Lonitab (Minoxidil Tablets) by Intas Pharmaceuticals Limited, India.