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Liver Disease: Management and Care of

Patients - 6KNIN337 Level: 6

Credits: 15

Module leader: Adam Riedlinger

Email: adam.riedlinger@kcl.ac.uk

Module deputy: TBC

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This handbook must be read in conjunction with module information provided on KEATS, the King’s E-Learning And Teaching Service. You will be given access to KEATS on enrolment. Important information relating to assessment and related regulations can be found in the Postgraduate Programme Handbook, available on KEATS and via the Nightingale Student Hub. This handbook can also be provided in alternative formats (such as large print) upon request to asc@kcl.ac.uk.

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Contents

Module overview .......................................................................................................... 4

Module aim ............................................................................................................... 4

Learning outcomes ................................................................................................... 4

Teaching arrangements ............................................................................................ 4

Submitting coursework ............................................................................................ 5

Assessment criteria ................................................................................................... 5

Formative assessment .............................................................................................. 5

Summative assessment............................................................................................. 5

Results and resubmissions for coursework .............................................................. 6

Learning outcomes and resources ............................................................................... 8

General reference ..................................................................................................... 8

Day 1 ............................................................................................................................. 8

Session 1 – Course Introduction, Ice Breaker and Quiz ........................................... 8

Session 2 – Chronic Liver Disease; Setting the Scene .............................................. 8

Session 3 – The Effect of Chronic Liver Disease on other Body Systems (Respiratory and Cardiovascular) ............................................................................ 9

Session 4 – Understanding and Assessing a Patient’s Liver Function and Dispelling the Myths about Haemostasis ................................................................. 9

Day 2............................................................................................................................. 10

Session 1 – Portal Hypertension and the Management of a Patient with a Variceal Haemorrhage .............................................................................................. 10

Session 2 – Ascites and Management ...................................................................... 10

Session 3 – Acute Kidney Injury and Hepatorenal Syndrome in Chronic Liver Disease ............................................................................................... 11

Session 4 – Nutrition in chronic liver disease .......................................................... 11

Day 3............................................................................................................................. 12

Session 1 – Hepatic Encephalopathy and Management in Chronic Liver Disease ............................................................................................... 12

Session 2 – Acute Pancreatitis ................................................................................. 12

Session 3 – Viral Hepatitis ....................................................................................... 13

Session 4 – Assignment Workshop .......................................................................... 13

Day 4............................................................................................................................. 14

Session 1 – Hepatocellular, Hepatobiliary and Pancreatic Carcinomas .................. 14

Session 2 – Overview and Management of Alcoholic Related Liver Disease ........... 14

Session 3 – The Jaundiced Patient ........................................................................... 15

Session 4 – Non-Alcoholic Fatty Liver Disease ........................................................ 15

Session 5 – Primary Biliary Cholangitis and Primary Sclerosing Cholangitis ......... 15

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Day 5 ............................................................................................................................. 16

Session 1 – Acute Liver Failure ................................................................................ 16

Session 2 – Introduction to Immunosuppression for the Post-transplant Patient . 16

Session 3 – Liver Transplant Assessment for Patients with Chronic Liver Disease 16

Module evaluation ........................................................................................................ 18

Action from previous evaluations ............................................................................. 18

Timetable...................................................................................................................... 18

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Module overview This module forms part of the BSc Nursing Studies. The module contributes to your programme of study by providing an overview of the current evidence base surrounding the diagnosis & treatment of common liver diseases.

The module can also be taken as a freestanding module.

Module aim This module will enable practitioners to develop their knowledge base in caring for patients with liver disease. The focus will predominately be on chronic liver disease, although the course will provide an overview of acute liver failure and transplantation.

Learning outcomes The learning outcomes of this course meet some of the nine liver care competencies as set out by the Royal College of Nursing, NHS Liver Care and the Department of Health in the “Caring for people with liver disease: a competence framework for nursing” (2013).

1. Analyse and apply the evidence base that underpins the medical and nursing management of patients with liver disorders, both in a Hepatology or general setting.

2. Appraise the knowledge and skills needed for assessment planning, delivery and evaluation

of care for patients with liver disease

3. Appraise and evaluate the contribution of nursing and other professional groups in the

management and delivery of effective care to patients with liver disease

4. Analyse the factors influencing health care promotion for patients with liver disease

5. Examine the factors which determine the provision of health care resources taking into

account the importance of cost, efficiency, quality and resources available

Teaching arrangements The educational approach is adult student centred, which builds on your experience as a qualified practitioner. You will experience a wide variety of teaching and learning strategies:

• Lecture and discussion

• Group work

• Tutorials

• Guided study

• Quiz

• Independent study

• Case study exploration

• E-learning

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Submitting coursework For this module you are assessed by Adam Riedlinger. All assessments are submitted online via TurnItIn (through the KEATS site).

Assessment criteria Essay — 2,000 words. This constitutes 100% of the overall grade. You will demonstrate an achievement of the course learning outcomes by writing an assignment addressing either a liver disease or a complication of liver disease as identified in a patient-based case study.

Formative assessment Students are advised to seek tutorial support from the course lecturer. This should be a student led

discussion focusing on the students’ essay. The student should provide a plan in which the key

themes are identified along with relevant literature using the bullet points below.

• Which patient case study have you chosen?

• What disease/complication aspect will you focus on?

• Identify the key references which you will use to support the pathophysiology/management of the chosen aspects

• Is the evidence clear? Are there any opposing views? How does it relate to your practice?

Summative assessment

• Your assignment must be in a structured essay format, but sub headings may be used. It

should include an introduction, main body and conclusion

• Critically appraise the management of either the chosen liver disease or complication of liver

disease which may be carried out to address the patients’ health care needs, this must

include a critical appraisal of the nurses’ role and nursing practice in relation to the

identified management

• Critically analyse the evidence-based literature in relation to both the patients problem,

interventions and nursing management

• Make recommendations for future nursing practice in relation to your analysis of the

interventions and nursing management of your identified complication

• Your assignment needs to be appropriately referenced using the JAN referencing system

(please see post-registration handbook for guidance).

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Coursework submission are provided on the modules KEATS site. It is essential that you use your candidate number on all assignments/examinations. Your candidate number, which will begin with X for the academic year 2017/18, will be available via Student Records on the King’s Intranet approximately one month after you enrol. If you are unable to submit your work by the deadline please refer to the information in your programme handbook on “mitigating circumstances”. If you require further support in these circumstances you are advised to contact KCLSU. Submission date for coursework: 17 July 2018 (11.59am) Resubmission: 16 October 2018 Late submissions will be accepted for 24 hours following the submission date. All work submitted late will be marked as normal but will be capped at the pass mark for the module. If your assignment is a hard copy please ensure you date stamp it and submit it to the submission room G15 James Clerk Maxwell Building. If your assignment is submitted electronically through TurnItIn, information about how to submit late will be provided on KEATS module sites under assessment information. Please label the file with your candidate number and double-check you have submitted the correct file. The external examiner for this module is Karen Staniland. Students are not to make direct contact with external examiners, in particular regarding their individual performance in assessments. The University and its Examination Boards in the ten Faculties (Institutes/Schools, King's Learning Institute and the Association of King's College (AKC), work with over 500 external examiners to ensure the quality and standard of our taught awards. Find the latest report on the External Examiners Report page, navigate to the Faculty of Nursing and Midwifery section.

Results and resubmissions for coursework Students will receive a provisional (unratified) mark for their coursework 4 weeks following submission. According to the method of submission as detailed on your KEATS site, if your work was submitted online you will be able to download marked coursework from KEATS; alternatively, if you completed a hard copy submission you can collect your coursework and feedback from the Nightingale Student Hub. To collect a hard copy assignment, you must provide your candidate number. Alternatively, you may send a stamped addressed envelope to the Nightingale Student Hub ensuring that this is large enough to accommodate your assignments and that you have applied sufficient postage. Hard copy assignments will be retained for four weeks; if you have not collected your assignment by then, it will be destroyed. Feedback will include the award of a numerical grade which remains provisional until ratified by the examination boards. The dates for the examination boards are available on KEATS. Ratified marks can be viewed via Student Records on the King’s Intranet, the Monday following the relevant examination board. The marking criteria by which your work is judged are provided in full in your programme handbook. Please also refer to the section in your programme handbook on plagiarism and how to avoid it. If you have a query about how to refer to a specific piece of work please ask your module leader, your group leader or a member of library staff for guidance or please use King’s Libguides site.

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The feedback you receive on your assignment will guide you towards how to do better next time or how to maintain your existing high standard! If you do not understand your mark or the feedback you receive please contact Adam Riedlinger. If you are unsuccessful, it is recommended that you contact the module leader before submitting your second attempt. This will enable the module leader to provide you with an appropriate level of support as you prepare to resubmit your work.

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Learning outcomes and resources

General reference Dooley J.S., Lok A.S.F., Burroughs A.K. & Heathcote E.J. (2011) Sherlock’s Diseases of the Liver and Biliary System. 12th ed. Wiley-Blackwell, Oxford.

Sargent S. (2009) Liver Diseases, An Essential Guide for Nurses and Health Care Professionals. Wiley-Blackwell, Oxford.

Bacon, B. R., O'Grady, J. G., Di Bisceglie, A. M., & Lake, J. R. (2006). Comprehensive clinical hepatology. Elsevier Ltd.

Day 1

Session 1 – Course Introduction, Ice Breaker and Quiz By the end of this session the students will be able to:

• Demonstrate familiarity with the course structure and content

• Demonstrate familiarity with other course students

• Understand the principles of e-learning and self-directed learning

• To understand how to access KEATS liver disease module 6KNIN337

• Differentiate between acute and chronic liver disease

• Acknowledge the common aetiologies of liver failure

• Understand the anatomy of the Liver and the main functions

Indicative reading Module Handbook.

Post-Qualification Handbook.

Hill C. (2009) Anatomy and Physiology. Chapter 1. In Sargent S. (2009) Liver Diseases; An

Essential Guide for Nurses and Health Care Professionals. Wiley-Blackwell, Oxford.

Session 2 – Chronic Liver Disease; Setting the Scene By the end of the session students will

• Understand the UK prevalence of chronic liver disease

• Understand the most common aetiologies

• Recognise stigmata of chronic liver disease and reasons for these

Indicative reading Lancet Commission - http://www.thelancet.com/commissions/crisis-of-liver-disease-in-the-uk

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Session 3 – The Effect of Chronic Liver Disease on other Body Systems (Respiratory and Cardiovascular) By the end of the session the student will be able to

• To analyse the respiratory and cardiovascular complications of chronic and acute liver failure

• To revise the relevant pathophysiology

• To examine current treatments and evaluate effectiveness

• Explore the current nursing management of respiratory and cardiovascular complications in

patients with liver diseases

Indicative reading Møller, S., & Bernardi, M. (2013). Interactions of the heart and the liver. European heart

journal, 34(36), 2804-2811.

Yang Y.Y. & Lin H.C. (2012) The heart: Pathophysiology and clinical implications of cirrhotic

cardiomyopathy. Journal of the Chinese Medical Association 75, 619-623.

Bolognesi, M., Di Pascoli, M., Verardo, A., & Gatta, A. (2014). Splanchnic vasodilation and

hyperdynamic circulatory syndrome in cirrhosis. World Journal of Gastroenterology: WJG, 20(10),

2555.

Session 4 – Understanding and Assessing a Patient’s Liver Function and Dispelling the Myths about Haemostasis By the end of the session the students will be able to:

• Differentiate between liver enzymes and liver function tests

• To analyse normal and abnormal values and the relation to liver disease

• To understand how Haemostasis changes in liver disease

• To debate appropriate interventions and precautions in managing coagulopathy in liver

disease

Indicative reading Greenslade L. (2009) Assessment of liver function and diagnostic studies in Sargent S. (ed) (2009)

Liver Diseases; An Essential Guide for Nurses and Health Care Professional. Wiley-Blackwell,

Oxford.

Khoury T., Ayman A.R., Cohen J., Daher S., Shmuel C. & Mizrahi M. (2016). The Complex Role of

Anticoagulation in Cirrhosis: An Updated Review of Where We Are and Where We Are Going.

Digestion, 93(2), 149-159.

Patch D. & Dhillon A.P. (2011) Chapter 3 Biopsy of the Liver in Dooley J.S., Lok A.S.F., Burroughs

A.K. & Heathcote E.J. (2011) Sherlock’s Diseases of the Liver and Biliary System. 12th ed. Wiley-

Blackwell, Oxford.

Northu P.G. & Caldwell S.H. (2013) Coagulation in Liver Disease; a guide for the clinician. Clinical

Gastroenterology and Hepatology 11, 1064-1074.

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Day 2

Session 1 – Portal Hypertension and the Management of a Patient with a Variceal Haemorrhage By the end of the session the student will be able to

• To revise the pathophysiology of portal hypertension and formation of varices

• To demonstrate knowledge of the SIGN guidelines for management of variceal bleeding

• To examine the emergency and long-term treatment strategies for portal hypertension

Indicative reading Fullwood D. (2012) Portal hypertension and varices in patients with liver cirrhosis. Nursing

Standard 26(48), 52-57.

National Institute for Clinical Excellence (2012) Acute upper gastrointestinal bleeding management.

Guideline 141 http://www.nice.org.uk/nicemedia/live/13762/59549/59549.pdf

Session 2 – Ascites and Management By the end of the session the student will be able to

• To examine the pathophysiology of ascites and diagnostic criteria

• To analyse the dietary, medical and surgical approaches to the management of patients with

ascites

• To analyse and evaluate the nursing management of patients with ascites

Indicative reading EASL (2010) Clinical Practice Guidelines on the management of ascites, spontaneous bacterial

peritonitis and hepatorenal syndrome in cirrhosis. Journal of Hepatology 53, 397-417.

Fullwood D. & Purushothaman (2014) Managing ascites in patients with chronic liver disease.

Nursing Standard 28(23), 51-58.

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Session 3 – Acute Kidney Injury and Hepatorenal Syndrome in Chronic Liver Disease By the end of the session the student will be able to

• To identify causes of acute kidney injury in patients with chronic liver disease and some of

the management strategies

• To demonstrate increased understanding of the pathophysiological factors underpinning

hepatorenal syndrome and the international ascites club diagnostic criteria

• To examine the current medical and nursing strategies for patients with hepatorenal

syndromes

Indicative reading Tsien C.D., Rabie R. & Wong F. (2013) Acute kidney injury in decompensated cirrhosis. GUT 62,

131-137.

Wadai H.M. (2012) Hepatorenal syndrome; a critical update. Seminars in Respiratory and Critical

Care Medicine 33(1), 55-69.

Session 4 – Causes of jaundice and care of the jaundiced patient

By the end of the session the student will be able to

• To revise the anatomy and physiology of liver cells and biliary system to understand the flow

of bile

• To examine the differences between conjugated and unconjugated bilirubin

• To examine the pre hepatic, hepatic and post hepatic causes of jaundice

• To analyse current treatments and nursing management

• To analyse and evaluate the psychological impact of altered body image

Indicative reading Clayton M. (2009) Jaundice in Sargent S. (Ed.) (2009) Liver Disease; An Essential Guide for

Nurses and Health Care Professionals. Wiley-Blackwell, Oxford.

Elias E. (2011) Chapter 11 Jaundice and Cholestasis in Dooley J.S., Lok A.S.F., Burroughs A.K. &

Heathcote E.J. (2011) Sherlock’s Diseases of the Liver and Biliary System. 12th ed. Wiley-Blackwell.

Oxford.

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Day 3

Session 1 – Hepatic Encephalopathy and Management in Chronic Liver Disease By the end of the session the student will be able to

• To revise the pathophysiology and underlying theories of hepatic encephalopathy

• To review current treatment therapies and effects

• Have an understanding of future therapies

• To analyse and review current nursing management

Indicative reading Houlston C. & O’Neil H. (2009) Hepatic Encephalopathy in Sargent S. (Ed.) (2009) Liver Disease;

An Essential Guide for Nursed and Health Care Professionals. Wiley-Blackwell. Oxford.

Vilstrup, H., Amodio, P., Bajaj, J., Cordoba, J., Ferenci, P., Mullen, K. D., ... & Wong, P. (2014). Hepatic encephalopathy in chronic liver disease: 2014 Practice Guideline by the American Association for the Study of Liver Diseases and the European Association for the Study of the Liver. Hepatology, 60(2), 715-735.

Session 2 – Acute Pancreatitis By the end of the session the student will be able to

• To revise the pathophysiology and underlying theories of pancreatitis

• Explore current epidemiology both worldwide and UK

• To review current treatment therapies and effects

• To analyse and review current nursing management

Indicative reading Banks P.A. et al. Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus. Gut 62.1(2013), 102-111.

Tenner, Scott, et al. American College of Gastroenterology guideline: management of acute pancreatitis. The American journal of gastroenterology 108.9(2013), 1400-1415.

Wu, Bechien U. & Banks P.A. Clinical management of patients with acute pancreatitis. Gastroenterology 144.6(2013), 1272-1281.

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Session 3 – Viral Hepatitis By the end of the session the student will be able to

• Understand the current modes of viral transmission of hepatitis

• Explore current epidemiology both worldwide and UK

• Analyse serological tests for the diagnosis and treatment of Hepatitis

• Understand current treatment options for patients with Hepatitis

Indicative reading Oakes K. (2014) Management of chronic hepatitis B virus. Nursing Times. 110(8), 20-24.

European Association For The Study Of The Liver. (2017). EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection. Journal of hepatology, 67(2), 370-398.

Pawlotsky, J. M., Aghemo, A., Back, D., Dusheiko, G., Forns, X., Puoti, M., & Sarrazin, C. (2015). EASL recommendations on treatment of hepatitis C 2015. J hepatol, 63(1), 199-236.

Session 4 – Assignment Workshop By the end of the session the student will be able to

• Understand the requirements of the module assessment

• Have an understanding of academic writing style and standards

• Have an understanding of plagiarism & how to avoid it

Indicative reading

Post-qualification handbook.

University plagiarism guidance (can be found via KEATS).

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Day 4

Session 1 – Hepatocellular, Hepatobiliary and Pancreatic Carcinomas By the end of the sessions the student will be able to

• To examine the incidence of Liver related cancers in the United Kingdom

• To review both medical and surgical treatment strategies

• Demonstrate increased understanding of the postoperative complication of hepatobiliary

surgery and procedures

• To examine current nursing management strategies for patients with liver related cancers

Indicative reading EASL (2012) Management of hepatocellular carcinoma

http://www.easl.eu/assets/application/files/d38c7689f123edf_file.pdf

Jervis N. (2009) in Sargent S.. (Ed.) (2009) Liver Disease; An Essential Guide for Nurses and

Health Care Professionals. Wiley-Blackwell, Oxford.

Session 2 – Overview and Management of Alcoholic Related Liver Disease By the end of the session the student will be able to

• To analyse current incidence and impact on the health service

• To examine the pathophysiology of alcoholic liver disease, including fatty liver, alcoholic

hepatitis and cirrhosis

• To appraise current management for both ALD and alcoholic hepatitis

Indicative reading Webb K. (2009) Alcohol Related Liver Disease in Sargent S. (Ed.) (2009) Liver Disease; An

Essential Guide for Nursed and Health Care Professionals. Wiley-Blackwell, Oxford.

https://www.drinkaware.co.uk/alcohol-facts/alcoholic-drinks-units/alcohol-limits-unit-guidelines/

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Session 3 – Nutrition in liver disease

By the end of the session the student will be able to

• To revise the alterations in energy metabolism found in chronic liver disease

• To review current treatment therapies and effects

• To analyse and review current nursing management

Indicative reading

Plauth M., Cabre E., Riggio O., Assis-Camilo, M., Pirlich M., Kondrup J. & Nolte W. (2006). ESPEN

guidelines on enteral nutrition: liver disease. Clinical Nutrition, 25(2), 285-294.

Johnson T. M., Overgard E. B., Cohen A. E., & DiBaise J.K. (2013). Nutrition assessment and management in advanced liver disease. Nutrition in Clinical Practice, 28(1), 15-29.

Cheung K., Lee S. S., & Raman M. (2012). Prevalence and mechanisms of malnutrition in patients with advanced liver disease, and nutrition management strategies. Clinical Gastroenterology and Hepatology, 10(2), 117-125.

Juakiem, W., Torres, D. M., & Harrison, S. A. (2014). Nutrition in cirrhosis and chronic liver disease. Clinics in liver disease, 18(1), 179-190.

Session 4 – Non-Alcoholic Fatty Liver Disease By the end of the session the student will be able to

• To understand the increasing incidence of NAFLD

• To examine the underlying pathophysiology, disease presentation and associated

complications

• To review the current evidence base management strategies

Indicative reading Nikolopoulos A. & Oben J.A. Non Alcoholic Fatty Liver Disease in Sargent S. (Ed.) (2009) Liver

Disease; An Essential Guide for Nursed and Health Care Professionals. Wiley-Blackwell, Oxford.

European Association for the Study of the Liver, & European Association for the Study of Diabetes (EASD. (2016). EASL-EASD-EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease. Obesity facts, 9(2), 65-90.

Session 5 – Primary Biliary Cholangitis and Primary Sclerosing Cholangitis By the end of the session the student will be able to

• To review the basic pathophysiology of cholestatic liver diseases

• To examine diagnostic testing and signs and symptoms

• To examine disease related complications

• Appraise the effectiveness of current medical, surgical and nursing management

Indicative reading Fullwood D. (2009) Primary Biliary Cirrhosis and Primary Biliary Cholangitis in Sargent S. (Ed.)

(2009) Liver Disease; An Essential Guide for Nursed and Health Care Professionals. Wiley-

Blackwell, Oxford.

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Lindor, K. D., Kowdley, K. V., & Harrison, M. E. (2015). ACG clinical guideline: primary sclerosing cholangitis. The American journal of gastroenterology, 110(5), 646.

Hirschfield, G. M., Beuers, U., Corpechot, C., Invernizzi, P., Jones, D., Marzioni, M., & Schramm, C. (2017). EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis. Journal of hepatology, 67(1), 145-172.

Day 5

Session 1 – Acute Liver Failure By the end of the session the student will be able to

• To examine the clinical presentations of hyper acute, acute and sub-acute liver failure.

• To recognise the main aetiologies of acute liver failure

• To examine clinical presentation and nursing management of encephalopathy and cerebral

oedema, renal failure, coagulopathy, metabolic, cardiovascular and respiratory

complications in acute liver failure

• Consider the indications for referral and transplantation criteria

• Evaluate the current and future research of acute liver failure management

Indicative reading Bernal W., Hyyrylainen A., Gera A., Audimoolam V.K., McPhail M.JW. et al (2013) Lessons from look-back in acute liver failure? A single centre experience of 3300 patients. Journal of Hepatology 59, 74-80.

Bernal W. & Wendon J. (2013). Acute liver failure. New England Journal of Medicine, 369(26).

European Association For The Study Of The Liver. (2017). EASL clinical practice guidelines: Management of acute (fulminant) liver failure.

Session 2 – Introduction to Immunosuppression for the Post-transplant Patient By the end of the session the student will be able to

• To examine current Immunosuppression therapies in transplantation

• To look at Immunosuppression for the treatment of specific diseases of the liver

Indicative reading Jadlowiec, C. C., Taner, T., & Wiesner, R. H. (2018). Immunosuppression: The Global

Picture. Schiff's Diseases of the Liver, Twelfth Edition, 1065-1078.

Session 3 – Issues in Liver Transplantation By the end of the session the student will be able to

• Appraise the current transplant assessment and listing criteria for chronic transplant

recipients

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Indicative reading Fullwood D., Jones F. & Lau-Walker M. (2011) Care of patients following liver transplantation.

Nursing Standard 25(49), 50-56.

Littlejohn W. & Routledge J. (2009) in Sargent S. (Ed.) (2009) Liver Disease; An Essential Guide

for Nursed and Health Care Professionals. Wiley-Blackwell, Oxford.

https://www.odt.nhs.uk/transplantation/liver/

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Module evaluation As part of the university’s Student Voice Strategy, King’s uses an electronic module evaluation system known as EvaSys. This provides an opportunity for you to feedback on different aspects of the module through a series of pre-set questions and qualitative comments. At the end of the module you will receive an automated invitation via your KCL email account to complete your evaluation online.

Please take the time to complete as your feedback is important. It informs ongoing developments to individual modules to ensure that the learning needs and expectations of the Faculty’s student community are met to a high standard.

To strengthen the feedback cycle, a report summarizing the quantitative results for the module as a whole and the module lead’s reflections on your feedback will be sent to you after the online evaluation survey has closed.

Action from previous evaluations 1. Assignment changed to avoid unintended plagiarism. 2. Presentations made available prior to sessions.

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Timetable Subject to change due to speaker availability.

Liver Disease: Care & Management of Patients

Teaching mode

Date Type of Session

Title Time Lecturer Room

Day 1

University based study

9 May 2018

Introduction Welcome and introduction to the liver course 11:00-11:30 Adam Riedlinger

FWB 2.48 Lecture

Introduction to the anatomy & physiology of the liver

11:30-12:15 Sheela Vinu Kurian

Chronic liver disease: setting the scene 12:15-13:00

Adam Riedlinger

The effect of chronic liver disease on other body systems (Respiratory and cardiovascular)

14:00-15:00

Understanding and assessing a patient’s Liver Function and dispelling the myths about Haemostasis

15:00-16:00

Day 2

University based study

10 May 2018

Self-study/e-learning

Tutorial appointments available 10:00-11:00 JCMB 2.43

Lecture

Portal Hypertension and managing a patient with a variceal bleed

11:00-12:00

Sheela Vinu Kurian

FWB 2.48

Ascites and management in patients with Chronic Liver disease

12:00-13:00

Hepatorenal syndrome and renal complications

14:00-15:00

Adam Riedlinger

Causes of jaundice and care of the jaundiced patient

15:00-16:00

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Day 3

University based study

11 May 2018

Self-study/e-learning

Tutorial appointments available 10:00-11:00 JCMB 2.43

Lecture

Managing patients with Hepatic Encephalopathy in Chronic Liver disease

11:00-12:00 Adam Riedlinger

FWB 2.48 Acute Pancreatitis 12:00-13:00

Viral Hepatitis 14:00-15:00 Kath Oakes

Essay workshop 15:00-16:00 Adam Riedlinger

Day 4 (Adults)

University based study

14 May 2018

Self-study/e-learning

Tutorial appointments available 10:00-11:00 JCMB 2.43

Lecture

HPB cancers 11:00-12:00 Wendy Martin

WEC Classroom

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Alcohol related liver disease 12:00-13:00 Adam Riedlinger

Nutrition in liver disease 14:00-15:00

NAFLD 15:00-15:30

Adam Riedlinger PBC/PBC 15:30-16:00

Day 5

University based study

15 May 2018

Lecture

Liver transplant surgery 10:00-11:00

WEC Classroom

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Acute Liver Failure and transplantation 11:00-12:30

Immunosuppression for the post-transplant patient

12:30-13:00

Issues in Transplantation for patients with chronic liver disease

14:00-16:00 Wendy Littlejohn

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Location key:

FWB – Franklin-Wilkins Building, Waterloo Campus

JCMB – James Clerk Maxwell Building, Waterloo Campus

WEC – Weston Education Centre, Denmark Hill Campus