Listing 16.2.1 Discontinued Subjects · 2014. 8. 22. · 2291 30MAR2010 Lost to Follow Up ... 1033...

Swedish Match AB - Protocol No. SM 07-01 Page 1 of 9
Listing 16.2.1 Discontinued Subjects Treatment Site Subject Date Withdrawn Primary Reason for Discontinuation Number Number Active snus 01 1003 06OCT2008 Withdrawal of Consent 1004 04JUL2008 Protocol Violation 1005 31DEC2008 Withdrawal of Consent 1007 21MAR2008 Adverse Event (Adverse Reaction) 1011 16OCT2008 Failure to achieve smoking reduction at Week 24 1013 25SEP2008 Failure to achieve smoking reduction at Week 24 1014 06SEP2008 Withdrawal of Consent 1015 19JUN2008 Protocol Violation 1019 10SEP2008 Failure to achieve smoking reduction at Week 24 1021 08SEP2008 Lost to Follow Up 1028 23SEP2008 Failure to achieve smoking reduction at Week 24 1029 03SEP2008 Lost to Follow Up 1031 23SEP2008 Failure to achieve smoking reduction at Week 24 1032 04APR2008 Withdrawal of Consent 1034 14MAY2008 Lost to Follow Up Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LDISC.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 39
Listing 16.2.1 Discontinued Subjects Treatment Site Subject Date Withdrawn Primary Reason for Discontinuation Number Number Active snus 01 1040 22MAY2008 Withdrawal of Consent 1042 03JUL2008 Withdrawal of Consent 1044 23MAY2008 Withdrawal of Consent 1045 14MAR2008 Adverse Event (Adverse Reaction) 1047 01JUL2008 Withdrawal of Consent 1050 18JUL2008 Lost to Follow Up 1207 01AUG2008 Withdrawal of Consent 1208 17SEP2008 Withdrawal of Consent 1209 20AUG2008 Withdrawal of Consent 1211 30AUG2008 Withdrawal of Consent 1215 05NOV2008 Failure to achieve smoking reduction at Week 24 1217 18NOV2008 Lost to Follow Up 1218 20AUG2008 Withdrawal of Consent 1219 04SEP2008 Withdrawal of Consent 1223 12FEB2009 Protocol Violation Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LDISC.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 39
Listing 16.2.1 Discontinued Subjects Treatment Site Subject Date Withdrawn Primary Reason for Discontinuation Number Number Active snus 01 1225 15OCT2008 Withdrawal of Consent 1227 18DEC2008 Lost to Follow Up 1232 21APR2009 Withdrawal of Consent 1234 08MAY2009 Withdrawal of Consent 1235 15JAN2010 Withdrawal of Consent 1236 08MAY2009 Withdrawal of Consent 1238 11SEP2009 Withdrawal of Consent 02 1327 28DEC2009 Withdrawal of Consent 1347 23OCT2009 Failure to achieve smoking reduction at Week 24 2004 11AUG2008 Failure to achieve smoking reduction at Week 24 2005 11AUG2008 Failure to achieve smoking reduction at Week 24 2007 11AUG2008 Failure to achieve smoking reduction at Week 24 2008 11AUG2008 Failure to achieve smoking reduction at Week 24 2011 13AUG2008 Failure to achieve smoking reduction at Week 24 2013 11AUG2008 Withdrawal of Consent Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LDISC.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 39
Listing 16.2.1 Discontinued Subjects Treatment Site Subject Date Withdrawn Primary Reason for Discontinuation Number Number Active snus 02 2014 11AUG2008 Failure to achieve smoking reduction at Week 24 2015 11AUG2008 Failure to achieve smoking reduction at Week 24 2019 13AUG2008 Withdrawal of Consent 2023 26AUG2008 Failure to achieve smoking reduction at Week 24 2031 01DEC2008 Withdrawal of Consent 2034 04SEP2008 Withdrawal of Consent 2038 05AUG2008 Withdrawal of Consent 2040 23SEP2008 Failure to achieve smoking reduction at Week 24 2255 08JUN2009 Failure to achieve smoking reduction at Week 24 2261 29JUN2009 Failure to achieve smoking reduction at Week 24 2264 08JUL2009 Failure to achieve smoking reduction at Week 24 2273 22JUL2009 Failure to achieve smoking reduction at Week 24 2276 22JUL2009 Failure to achieve smoking reduction at Week 24 2278 21JUL2009 Failure to achieve smoking reduction at Week 24 2281 21JUL2009 Failure to achieve smoking reduction at Week 24 Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LDISC.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 39
Listing 16.2.1 Discontinued Subjects Treatment Site Subject Date Withdrawn Primary Reason for Discontinuation Number Number Active snus 02 2284 22JUL2009 Failure to achieve smoking reduction at Week 24 2285 21JUL2009 Failure to achieve smoking reduction at Week 24 2287 05FEB2010 Lost to Follow Up 2289 20JAN2010 Lost to Follow Up 2291 30MAR2010 Lost to Follow Up 2294 14SEP2009 Failure to achieve smoking reduction at Week 24 2299 08SEP2009 Failure to achieve smoking reduction at Week 24 2301 08SEP2009 Failure to achieve smoking reduction at Week 24 2303 08SEP2009 Failure to achieve smoking reduction at Week 24 2306 30MAR2010 Lost to Follow Up Placebo snus 01 1001 23DEC2008 Failure to achieve smoking reduction at Week 24 1006 16JUL2008 Failure to achieve smoking reduction at Week 24 1010 29JUL2008 Failure to achieve smoking reduction at Week 24 1012 31JUL2008 Failure to achieve smoking reduction at Week 24 1017 06SEP2008 Withdrawal of Consent Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LDISC.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 39
Listing 16.2.1 Discontinued Subjects Treatment Site Subject Date Withdrawn Primary Reason for Discontinuation Number Number Placebo snus 01 1018 15APR2008 Withdrawal of Consent 1020 14AUG2008 Protocol Violation 1022 31MAR2008 Withdrawal of Consent 1024 23JUN2008 Protocol Violation 1025 23SEP2008 Failure to achieve smoking reduction at Week 24 1026 19MAY2008 Withdrawal of Consent 1027 18SEP2008 Failure to achieve smoking reduction at Week 24 1033 22SEP2008 Failure to achieve smoking reduction at Week 24 1035 31JUL2008 Failure to achieve smoking reduction at Week 24 1036 12MAY2008 Protocol Violation 1039 22MAY2008 Protocol Violation 1041 10SEP2008 Withdrawal of Consent 1043 20NOV2008 Failure to achieve smoking reduction at Week 24 1046 13SEP2008 Protocol Violation 1048 01JUL2008 Withdrawal of Consent Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LDISC.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 39
Listing 16.2.1 Discontinued Subjects Treatment Site Subject Date Withdrawn Primary Reason for Discontinuation Number Number Placebo snus 01 1049 30JUN2008 Withdrawal of Consent 1206 05AUG2008 Withdrawal of Consent 1213 15DEC2008 Lost to Follow Up 1214 30APR2009 Lost to Follow Up 1221 19NOV2008 Withdrawal of Consent 1222 26MAR2009 Lost to Follow Up 1224 17FEB2009 Other: OTHER:ICF WITHDRAWAL 1228 29DEC2008 Withdrawal of Consent 1229 17FEB2009 Lost to Follow Up 1231 28JUL2009 Failure to achieve smoking reduction at Week 24 1241 09MAY2009 Lost to Follow Up 1247 22JAN2010 Lost to Follow Up 02 1342 14OCT2009 Failure to achieve smoking reduction at Week 24 1348 23OCT2009 Failure to achieve smoking reduction at Week 24 1349 06JAN2010 Lost to Follow Up Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LDISC.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 39
Listing 16.2.1 Discontinued Subjects Treatment Site Subject Date Withdrawn Primary Reason for Discontinuation Number Number Placebo snus 02 2006 11AUG2008 Failure to achieve smoking reduction at Week 24 2009 13AUG2008 Failure to achieve smoking reduction at Week 24 2012 13AUG2008 Failure to achieve smoking reduction at Week 24 2017 08AUG2008 Failure to achieve smoking reduction at Week 24 2018 13AUG2008 Failure to achieve smoking reduction at Week 24 2020 20AUG2008 Failure to achieve smoking reduction at Week 24 2024 15OCT2008 Withdrawal of Consent 2037 05AUG2008 Withdrawal of Consent 2041 25SEP2008 Withdrawal of Consent 2043 07JUL2008 Withdrawal of Consent 2046 01OCT2008 Failure to achieve smoking reduction at Week 24 2263 08JUL2009 Failure to achieve smoking reduction at Week 24 2268 17JUL2009 Failure to achieve smoking reduction at Week 24 2269 13JUL2009 Failure to achieve smoking reduction at Week 24 2272 20JUL2009 Failure to achieve smoking reduction at Week 24 Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LDISC.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 39
Listing 16.2.1 Discontinued Subjects Treatment Site Subject Date Withdrawn Primary Reason for Discontinuation Number Number Placebo snus 02 2283 22JUL2009 Failure to achieve smoking reduction at Week 24 2286 21JUL2009 Failure to achieve smoking reduction at Week 24 2288 24AUG2009 Failure to achieve smoking reduction at Week 24 2290 15FEB2010 Lost to Follow Up 2292 25AUG2009 Failure to achieve smoking reduction at Week 24 2293 30MAR2010 Lost to Follow Up 2297 05MAR2010 Lost to Follow Up 2298 05MAR2010 Lost to Follow Up 2304 15SEP2009 Failure to achieve smoking reduction at Week 24 3022 19NOV2009 Withdrawal of Consent Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LDISC.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 39
Listing 16.2.2 Informed Consent
Treatment Site Subject Date Informed Consent Number Number Signed Active snus 01 1003 28JAN2008 1004 30JAN2008 1005 30JAN2008 1007 04FEB2008 1008 04FEB2008 1011 07FEB2008 1013 08FEB2008 1014 09FEB2008 1015 09FEB2008 1019 13FEB2008 1021 14FEB2008 1023 18FEB2008 1028 20FEB2008 1029 21FEB2008 1030 21FEB2008
Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LINFCON.SAS Executed: 16AUG2010, 12:01 The data presented in this Listing are contained in CRF page 2
Treatment Site Subject Date Informed Consent Number Number Signed Active snus 01 1031 21FEB2008 1032 22FEB2008 1034 22FEB2008 1038 26FEB2008 1040 26FEB2008 1042 27FEB2008 1044 29FEB2008 1045 29FEB2008 1047 03MAR2008 1050 11MAR2008 1207 12MAY2008 1208 13MAY2008 1209 13MAY2008 1211 13MAY2008 1212 15MAY2008
Treatment Site Subject Date Informed Consent Number Number Signed Active snus 01 1215 23MAY2008 1217 26MAY2008 1218 27MAY2008 1219 02JUN2008 1223 05JUN2008 1225 05JUN2008 1227 07JUN2008 1232 04FEB2009 1233 05FEB2009 1234 06FEB2009 1235 10FEB2009 1236 11FEB2009 1238 14FEB2009 1242 14FEB2009 1244 14FEB2009
Treatment Site Subject Date Informed Consent Number Number Signed Active snus 01 1246 14FEB2009 02 1327 20APR2009 1328 20APR2009 1329 20APR2009 1331 20APR2009 1332 20APR2009 1335 20APR2009 1337 22APR2009 1338 24APR2009 1339 24APR2009 1343 01MAY2009 1345 01MAY2009 1347 29APR2009 2003 18FEB2008 2004 18FEB2008
Treatment Site Subject Date Informed Consent Number Number Signed Active snus 02 2005 18FEB2008 2007 19FEB2008 2008 19FEB2008 2011 20FEB2008 2013 21FEB2008 2014 21FEB2008 2015 21FEB2008 2019 21FEB2008 2021 05MAR2008 2023 05MAR2008 2028 18MAR2008 2029 18MAR2008 2030 18MAR2008 2031 20MAR2008 2032 25MAR2008
Treatment Site Subject Date Informed Consent Number Number Signed Active snus 02 2034 25MAR2008 2038 01APR2008 2040 03APR2008 2042 04APR2008 2044 10APR2008 2045 10APR2008 2047 10APR2008 2050 24APR2008 2205 18SEP2008 2208 25SEP2008 2209 26SEP2008 2213 02OCT2008 2214 03OCT2008 2215 20OCT2008 2217 20OCT2008
Treatment Site Subject Date Informed Consent Number Number Signed Active snus 02 2219 23OCT2008 2222 03NOV2008 2226 05NOV2008 2227 05NOV2008 2228 05NOV2008 2230 07NOV2008 2231 10NOV2008 2234 10NOV2008 2238 28NOV2008 2239 04DEC2008 2240 04DEC2008 2241 04DEC2008 2242 04DEC2008 2245 04DEC2008 2247 09DEC2008
Treatment Site Subject Date Informed Consent Number Number Signed Active snus 02 2248 12DEC2008 2251 16DEC2008 2253 16DEC2008 2255 23DEC2008 2257 27DEC2008 2261 12JAN2009 2262 12JAN2009 2264 21JAN2009 2265 22JAN2009 2266 22JAN2009 2267 22JAN2009 2273 04FEB2009 2275 04FEB2009 2276 04FEB2009 2277 04FEB2009
Treatment Site Subject Date Informed Consent Number Number Signed Active snus 02 2278 04FEB2009 2281 04FEB2009 2284 04FEB2009 2285 04FEB2009 2287 25FEB2009 2289 05MAR2009 2291 05MAR2009 2294 23MAR2009 2295 23MAR2009 2296 23MAR2009 2299 24MAR2009 2301 27MAR2009 2303 27MAR2009 2306 06APR2009 3003 16MAY2008
Treatment Site Subject Date Informed Consent Number Number Signed Active snus 02 3004 26MAY2008 3007 05JUN2008 3008 05JUN2008 3011 23JUN2008 3013 24JUN2008 3014 25JUN2008 3015 26JUN2008 3019 01JUL2008 3021 03JUL2008 3023 16JUL2008 3028 31JUL2008 3029 31JUL2008 3030 05AUG2008 3031 05AUG2008 3032 06AUG2008
Treatment Site Subject Date Informed Consent Number Number Signed Active snus 02 3034 08AUG2008 3038 22AUG2008 3040 02SEP2008 3042 09SEP2008 3044 09SEP2008 3045 10SEP2008 3047 15SEP2008 3050 17SEP2008 Placebo snus 01 1001 28JAN2008 1002 28JAN2008 1006 30JAN2008 1009 06FEB2008 1010 07FEB2008 1012 07FEB2008 1016 09FEB2008
Treatment Site Subject Date Informed Consent Number Number Signed Placebo snus 01 1017 09FEB2008 1018 11FEB2008 1020 13FEB2008 1022 14FEB2008 1024 19FEB2008 1025 19FEB2008 1026 19FEB2008 1027 20FEB2008 1033 22FEB2008 1035 25FEB2008 1036 25FEB2008 1037 26FEB2008 1039 26FEB2008 1041 27FEB2008 1043 27FEB2008
Treatment Site Subject Date Informed Consent Number Number Signed Placebo snus 01 1046 29FEB2008 1048 03MAR2008 1049 06MAR2008 1205 09MAY2008 1206 09MAY2008 1210 13MAY2008 1213 21MAY2008 1214 23MAY2008 1216 26MAY2008 1220 03JUN2008 1221 04JUN2008 1222 04JUN2008 1224 05JUN2008 1226 06JUN2008 1228 07JUN2008
Treatment Site Subject Date Informed Consent Number Number Signed Placebo snus 01 1229 07JUN2008 1230 21AUG2008 1231 03FEB2009 1237 14FEB2009 1239 14FEB2009 1240 14FEB2009 1241 14FEB2009 1243 14FEB2009 1245 14FEB2009 1247 23FEB2009 02 1325 06APR2009 1326 20APR2009 1330 20APR2009 1333 20APR2009 1334 20APR2009
Treatment Site Subject Date Informed Consent Number Number Signed Placebo snus 02 1336 20APR2009 1340 24APR2009 1341 28APR2009 1342 01MAY2009 1344 01MAY2009 1346 01MAY2009 1348 29APR2009 1349 29APR2009 2001 11FEB2008 2002 11FEB2008 2006 18FEB2008 2009 20FEB2008 2010 20FEB2008 2012 20FEB2008 2016 21FEB2008
Treatment Site Subject Date Informed Consent Number Number Signed Placebo snus 02 2017 21FEB2008 2018 21FEB2008 2020 05MAR2008 2022 05MAR2008 2024 06MAR2008 2025 17MAR2008 2026 17MAR2008 2027 17MAR2008 2033 25MAR2008 2035 25MAR2008 2036 25MAR2008 2037 01APR2008 2039 03APR2008 2041 03APR2008 2043 08APR2008
Treatment Site Subject Date Informed Consent Number Number Signed Placebo snus 02 2046 10APR2008 2048 15APR2008 2049 18APR2008 2206 18SEP2008 2207 23SEP2008 2210 26SEP2008 2211 26SEP2008 2212 29SEP2008 2216 20OCT2008 2218 22OCT2008 2220 28OCT2008 2221 03NOV2008 2223 03NOV2008 2224 03NOV2008 2225 04NOV2008
Treatment Site Subject Date Informed Consent Number Number Signed Placebo snus 02 2229 05NOV2008 2232 10NOV2008 2233 10NOV2008 2235 21NOV2008 2236 24NOV2008 2237 24NOV2008 2243 04DEC2008 2244 04DEC2008 2246 09DEC2008 2249 15DEC2008 2250 16DEC2008 2252 16DEC2008 2254 16DEC2008 2256 25DEC2008 2258 26DEC2008
Treatment Site Subject Date Informed Consent Number Number Signed Placebo snus 02 2259 26DEC2008 2260 30DEC2008 2263 21JAN2009 2268 27JAN2009 2269 28JAN2009 2270 30JAN2009 2271 30JAN2009 2272 04FEB2009 2274 04FEB2009 2279 04FEB2009 2280 04FEB2009 2282 04FEB2009 2283 04FEB2009 2286 04FEB2009 2288 05MAR2009
Treatment Site Subject Date Informed Consent Number Number Signed Placebo snus 02 2290 05MAR2009 2292 05MAR2009 2293 23MAR2009 2297 23MAR2009 2298 23MAR2009 2300 24MAR2009 2302 27MAR2009 2304 27MAR2009 2305 27MAR2009 3001 07MAY2008 3002 07MAY2008 3006 02JUN2008 3009 05JUN2008 3010 06JUN2008 3012 23JUN2008
Treatment Site Subject Date Informed Consent Number Number Signed Placebo snus 02 3016 30JUN2008 3017 01JUL2008 3018 01JUL2008 3020 02JUL2008 3022 04JUL2008 3024 16JUL2008 3025 31JUL2008 3026 31JUL2008 3027 31JUL2008 3033 08AUG2008 3035 12AUG2008 3036 12AUG2008 3037 12AUG2008 3039 01SEP2008 3041 09SEP2008
Treatment Site Subject Date Informed Consent Number Number Signed Placebo snus 02 3043 09SEP2008 3046 15SEP2008 3048 15SEP2008 3049 17SEP2008
Listing 16.2.3 Subjects Included in Analysis Populations
Treatment Site Subject Population Number Number ITT MITT Safety Active snus 01 1003 Yes Yes Yes 1004 Yes No Yes 1005 Yes Yes Yes 1007 Yes No Yes 1008 Yes Yes Yes 1011 Yes No Yes 1013 Yes No Yes 1014 Yes No Yes 1015 Yes No Yes 1019 Yes No Yes 1021 Yes No Yes 1023 Yes Yes Yes 1028 Yes No Yes 1029 Yes No Yes 1030 Yes Yes Yes
Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LPOP.SAS Executed: 16AUG2010, 11:57
Treatment Site Subject Population Number Number ITT MITT Safety Active snus 01 1031 Yes No Yes 1032 Yes No Yes 1034 Yes No Yes 1038 Yes Yes Yes 1040 Yes No Yes 1042 Yes No Yes 1044 Yes No Yes 1045 Yes No Yes 1047 Yes No Yes 1050 Yes No Yes 1207 Yes No Yes 1208 Yes No Yes 1209 Yes No Yes 1211 Yes No Yes 1212 Yes Yes Yes
Treatment Site Subject Population Number Number ITT MITT Safety Active snus 01 1215 Yes No Yes 1217 Yes No Yes 1218 Yes No Yes 1219 Yes No Yes 1223 Yes No Yes 1225 Yes No Yes 1227 Yes No Yes 1232 Yes No Yes 1233 Yes Yes Yes 1234 Yes No Yes 1235 Yes Yes Yes 1236 Yes No Yes 1238 Yes Yes Yes 1242 Yes Yes Yes 1244 Yes Yes Yes
Treatment Site Subject Population Number Number ITT MITT Safety Active snus 01 1246 Yes Yes Yes 02 1327 Yes Yes Yes 1328 Yes Yes Yes 1329 Yes Yes Yes 1331 Yes Yes Yes 1332 Yes Yes Yes 1335 Yes Yes Yes 1337 Yes Yes Yes 1338 Yes Yes Yes 1339 Yes Yes Yes 1343 Yes Yes Yes 1345 Yes Yes Yes 1347 Yes No Yes 2003 Yes Yes Yes 2004 Yes No Yes
Treatment Site Subject Population Number Number ITT MITT Safety Active snus 02 2005 Yes No Yes 2007 Yes No Yes 2008 Yes No Yes 2011 Yes No Yes 2013 Yes Yes Yes 2014 Yes No Yes 2015 Yes No Yes 2019 Yes Yes Yes 2021 Yes Yes Yes 2023 Yes No Yes 2028 Yes Yes Yes 2029 Yes Yes Yes 2030 Yes Yes Yes 2031 Yes Yes Yes 2032 Yes Yes Yes
Treatment Site Subject Population Number Number ITT MITT Safety Active snus 02 2034 Yes Yes Yes 2038 Yes No Yes 2040 Yes No Yes 2042 Yes Yes Yes 2044 Yes Yes Yes 2045 Yes Yes Yes 2047 Yes Yes Yes 2050 Yes Yes Yes 2205 Yes Yes Yes 2208 Yes Yes Yes 2209 Yes Yes Yes 2213 Yes Yes Yes 2214 Yes Yes Yes 2215 Yes Yes Yes 2217 Yes Yes Yes
Treatment Site Subject Population Number Number ITT MITT Safety Active snus 02 2219 Yes Yes Yes 2222 Yes Yes Yes 2226 Yes Yes Yes 2227 Yes Yes Yes 2228 Yes Yes Yes 2230 Yes Yes Yes 2231 Yes Yes Yes 2234 Yes Yes Yes 2238 Yes Yes Yes 2239 Yes Yes Yes 2240 Yes Yes Yes 2241 Yes Yes Yes 2242 Yes Yes Yes 2245 Yes Yes Yes 2247 Yes Yes Yes
Treatment Site Subject Population Number Number ITT MITT Safety Active snus 02 2248 Yes Yes Yes 2251 Yes Yes Yes 2253 Yes Yes Yes 2255 Yes No Yes 2257 Yes Yes Yes 2261 Yes No Yes 2262 Yes Yes Yes 2264 Yes No Yes 2265 Yes Yes Yes 2266 Yes Yes Yes 2267 Yes Yes Yes 2273 Yes No Yes 2275 Yes Yes Yes 2276 Yes No Yes 2277 Yes Yes Yes
Treatment Site Subject Population Number Number ITT MITT Safety Active snus 02 2278 Yes No Yes 2281 Yes No Yes 2284 Yes No Yes 2285 Yes No Yes 2287 Yes Yes Yes 2289 Yes Yes Yes 2291 Yes Yes Yes 2294 Yes No Yes 2295 Yes Yes Yes 2296 Yes Yes Yes 2299 Yes No Yes 2301 Yes No Yes 2303 Yes No Yes 2306 Yes Yes Yes 3003 Yes Yes Yes
Treatment Site Subject Population Number Number ITT MITT Safety Active snus 02 3004 Yes Yes Yes 3007 Yes Yes Yes 3008 Yes Yes Yes 3011 Yes Yes Yes 3013 Yes Yes Yes 3014 Yes Yes Yes 3015 Yes Yes Yes 3019 Yes Yes Yes 3021 Yes Yes Yes 3023 Yes Yes Yes 3028 Yes Yes Yes 3029 Yes Yes Yes 3030 Yes Yes Yes 3031 Yes Yes Yes 3032 Yes Yes Yes
Treatment Site Subject Population Number Number ITT MITT Safety Active snus 02 3034 Yes Yes Yes 3038 Yes Yes Yes 3040 Yes Yes Yes 3042 Yes Yes Yes 3044 Yes Yes Yes 3045 Yes Yes Yes 3047 Yes Yes Yes 3050 Yes Yes Yes Placebo snus 01 1001 Yes No Yes 1002 Yes Yes Yes 1006 Yes No Yes 1009 Yes Yes Yes 1010 Yes No Yes 1012 Yes No Yes 1016 Yes Yes Yes
Treatment Site Subject Population Number Number ITT MITT Safety Placebo snus 01 1017 Yes No Yes 1018 Yes No Yes 1020 Yes No Yes 1022 Yes No Yes 1024 Yes No Yes 1025 Yes No Yes 1026 Yes No Yes 1027 Yes No Yes 1033 Yes No Yes 1035 Yes No Yes 1036 Yes No Yes 1037 Yes Yes Yes 1039 Yes No Yes 1041 Yes No Yes 1043 Yes No Yes
Treatment Site Subject Population Number Number ITT MITT Safety Placebo snus 01 1046 Yes No Yes 1048 Yes No Yes 1049 Yes No Yes 1205 Yes Yes Yes 1206 Yes No Yes 1210 Yes Yes Yes 1213 Yes No Yes 1214 Yes Yes Yes 1216 Yes Yes Yes 1220 Yes Yes Yes 1221 Yes No Yes 1222 Yes No Yes 1224 Yes Yes Yes 1226 Yes Yes Yes 1228 Yes No Yes
Treatment Site Subject Population Number Number ITT MITT Safety Placebo snus 01 1229 Yes No Yes 1230 Yes Yes Yes 1231 Yes No Yes 1237 Yes Yes Yes 1239 Yes Yes Yes 1240 Yes Yes Yes 1241 Yes No Yes 1243 Yes Yes Yes 1245 Yes Yes Yes 1247 Yes Yes Yes 02 1325 Yes Yes Yes 1326 Yes Yes Yes 1330 Yes Yes Yes 1333 Yes Yes Yes 1334 Yes Yes Yes
Treatment Site Subject Population Number Number ITT MITT Safety Placebo snus 02 1336 Yes Yes Yes 1340 Yes Yes Yes 1341 Yes Yes Yes 1342 Yes No Yes 1344 Yes Yes Yes 1346 Yes Yes Yes 1348 Yes No Yes 1349 Yes Yes Yes 2001 Yes Yes Yes 2002 Yes Yes Yes 2006 Yes No Yes 2009 Yes No Yes 2010 Yes Yes Yes 2012 Yes No Yes 2016 Yes Yes Yes
Treatment Site Subject Population Number Number ITT MITT Safety Placebo snus 02 2017 Yes No Yes 2018 Yes No Yes 2020 Yes No Yes 2022 Yes Yes Yes 2024 Yes Yes Yes 2025 Yes Yes Yes 2026 Yes Yes Yes 2027 Yes Yes Yes 2033 Yes Yes Yes 2035 Yes Yes Yes 2036 Yes Yes Yes 2037 Yes No Yes 2039 Yes Yes Yes 2041 Yes No Yes 2043 Yes No Yes
Treatment Site Subject Population Number Number ITT MITT Safety Placebo snus 02 2046 Yes No Yes 2048 Yes Yes Yes 2049 Yes Yes Yes 2206 Yes Yes Yes 2207 Yes Yes Yes 2210 Yes Yes Yes 2211 Yes Yes Yes 2212 Yes Yes Yes 2216 Yes Yes Yes 2218 Yes Yes Yes 2220 Yes Yes Yes 2221 Yes Yes Yes 2223 Yes Yes Yes 2224 Yes Yes Yes 2225 Yes Yes Yes
Treatment Site Subject Population Number Number ITT MITT Safety Placebo snus 02 2229 Yes Yes Yes 2232 Yes Yes Yes 2233 Yes Yes Yes 2235 Yes Yes Yes 2236 Yes Yes Yes 2237 Yes Yes Yes 2243 Yes Yes Yes 2244 Yes Yes Yes 2246 Yes Yes Yes 2249 Yes Yes Yes 2250 Yes Yes Yes 2252 Yes Yes Yes 2254 Yes Yes Yes 2256 Yes Yes Yes 2258 Yes Yes Yes
Treatment Site Subject Population Number Number ITT MITT Safety Placebo snus 02 2259 Yes Yes Yes 2260 Yes Yes Yes 2263 Yes No Yes 2268 Yes No Yes 2269 Yes No Yes 2270 Yes No Yes 2271 Yes Yes Yes 2272 Yes No Yes 2274 Yes Yes Yes 2279 Yes Yes Yes 2280 Yes Yes Yes 2282 Yes Yes Yes 2283 Yes No Yes 2286 Yes No Yes 2288 Yes No Yes
Treatment Site Subject Population Number Number ITT MITT Safety Placebo snus 02 2290 Yes Yes Yes 2292 Yes No Yes 2293 Yes Yes Yes 2297 Yes Yes Yes 2298 Yes Yes Yes 2300 Yes Yes Yes 2302 Yes Yes Yes 2304 Yes No Yes 2305 Yes Yes Yes 3001 Yes Yes Yes 3002 Yes Yes Yes 3006 Yes Yes Yes 3009 Yes Yes Yes 3010 Yes Yes Yes 3012 Yes Yes Yes
Treatment Site Subject Population Number Number ITT MITT Safety Placebo snus 02 3016 Yes Yes Yes 3017 Yes Yes Yes 3018 Yes Yes Yes 3020 Yes Yes Yes 3022 Yes No Yes 3024 Yes Yes Yes 3025 Yes Yes Yes 3026 Yes Yes Yes 3027 Yes Yes Yes 3033 Yes Yes Yes 3035 Yes Yes Yes 3036 Yes Yes Yes 3037 Yes Yes Yes 3039 Yes Yes Yes 3041 Yes Yes Yes
Treatment Site Subject Population Number Number ITT MITT Safety Placebo snus 02 3043 Yes Yes Yes 3046 Yes Yes Yes 3048 Yes Yes Yes 3049 Yes Yes Yes
Listing 16.2.4.1 Demographic Data
Treatment Site Subject Randomisation Date of Age Gender Number Number Date Birth (years) Active snus 01 1031 21FEB2008 36 Male 1032 22FEB2008 46 Male 1034 22FEB2008 28 Male 1038 26FEB2008 46 Male 1040 26FEB2008 49 Male 1042 27FEB2008 29 Male 1044 29FEB2008 55 Male 1045 29FEB2008 46 Male 1047 03MAR2008 35 Male 1050 11MAR2008 44 Male 1207 12MAY2008 47 Male 1208 13MAY2008 36 Female 1209 13MAY2008 57 Female 1211 13MAY2008 40 Female 1212 15MAY2008 46 Male
Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LDEMOG.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
Treatment Site Subject Randomisation Date of Age Gender Number Number Date Birth (years) Active snus 01 1246 14FEB2009 38 Male 02 1327 20APR2009 20 Male 1328 20APR2009 25 Female 1329 20APR2009 27 Male 1331 20APR2009 23 Female 1332 20APR2009 27 Female 1335 20APR2009 38 Male 1337 22APR2009 39 Female 1338 24APR2009 54 Female 1339 24APR2009 45 Female 1343 01MAY2009 32 Female 1345 01MAY2009 24 Female 1347 29APR2009 42 Male 2003 18FEB2008 28 Female 2004 18FEB2008 47 Male
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
Treatment Site Subject Randomisation Date of Age Gender Number Number Date Birth (years) Active snus 02 2005 18FEB2008 37 Female 2007 19FEB2008 49 Male 2008 19FEB2008 45 Male 2011 20FEB2008 57 Female 2013 21FEB2008 51 Female 2014 21FEB2008 32 Female 2015 21FEB2008 32 Male 2019 21FEB2008 49 Female 2021 05MAR2008 34 Female 2023 05MAR2008 52 Female 2028 18MAR2008 64 Female 2029 18MAR2008 41 Female 2030 18MAR2008 55 Female 2031 20MAR2008 23 Male 2032 25MAR2008 47 Male
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
Treatment Site Subject Randomisation Date of Age Gender Number Number Date Birth (years) Active snus 02 2034 25MAR2008 60 Female 2038 01APR2008 45 Female 2040 03APR2008 40 Female 2042 04APR2008 48 Female 2044 10APR2008 30 Female 2045 10APR2008 52 Female 2047 10APR2008 23 Female 2050 24APR2008 49 Female 2205 18SEP2008 24 Male 2208 25SEP2008 39 Male 2209 26SEP2008 56 Female 2213 02OCT2008 31 Female 2214 03OCT2008 28 Female 2215 20OCT2008 48 Male 2217 20OCT2008 28 Female
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
Treatment Site Subject Randomisation Date of Age Gender Number Number Date Birth (years) Active snus 02 2219 23OCT2008 45 Female 2222 03NOV2008 41 Female 2226 05NOV2008 43 Male 2227 05NOV2008 35 Male 2228 05NOV2008 41 Female 2230 07NOV2008 56 Female 2231 10NOV2008 60 Female 2234 10NOV2008 54 Male 2238 28NOV2008 51 Female 2239 04DEC2008 52 Female 2240 04DEC2008 29 Female 2241 04DEC2008 27 Male 2242 04DEC2008 55 Female 2245 04DEC2008 46 Female 2247 09DEC2008 53 Male
(
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
Treatment Site Subject Randomisation Date of Age Gender Number Number Date Birth (years) Active snus 02 2248 12DEC2008 45 Female 2251 16DEC2008 52 Female 2253 16DEC2008 45 Male 2255 23DEC2008 33 Female 2257 27DEC2008 57 Male 2261 12JAN2009 39 Female 2262 12JAN2009 52 Female 2264 21JAN2009 56 Female 2265 22JAN2009 43 Female 2266 22JAN2009 48 Female 2267 22JAN2009 41 Female 2273 04FEB2009 55 Female 2275 04FEB2009 52 Female 2276 04FEB2009 51 Female 2277 04FEB2009 50 Female
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
Treatment Site Subject Randomisation Date of Age Gender Number Number Date Birth (years) Active snus 02 2278 04FEB2009 40 Male 2281 04FEB2009 33 Male 2284 04FEB2009 32 Male 2285 04FEB2009 47 Female 2287 25FEB2009 51 Male 2289 05MAR2009 39 Male 2291 05MAR2009 29 Male 2294 23MAR2009 47 Male 2295 23MAR2009 43 Male 2296 23MAR2009 26 Female 2299 24MAR2009 43 Female 2301 27MAR2009 55 Male 2303 27MAR2009 49 Female 2306 06APR2009 52 Female 3003 16MAY2008 38 Female
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6) (
(b) (6)
(b) (6)
(b) (6)
Treatment Site Subject Randomisation Date of Age Gender Number Number Date Birth (years) Active snus 02 3004 26MAY2008 50 Male 3007 05JUN2008 48 Female 3008 05JUN2008 50 Female 3011 23JUN2008 45 Male 3013 24JUN2008 51 Male 3014 25JUN2008 50 Female 3015 26JUN2008 34 Male 3019 01JUL2008 35 Female 3021 03JUL2008 48 Female 3023 16JUL2008 56 Female 3028 31JUL2008 50 Male 3029 31JUL2008 37 Female 3030 05AUG2008 44 Male 3031 05AUG2008 53 Female 3032 06AUG2008 43 Female
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
Treatment Site Subject Randomisation Date of Age Gender Number Number Date Birth (years) Active snus 02 3034 08AUG2008 57 Female 3038 22AUG2008 38 Female 3040 02SEP2008 46 Female 3042 09SEP2008 58 Female 3044 09SEP2008 46 Female 3045 10SEP2008 50 Female 3047 15SEP2008 43 Female 3050 17SEP2008 52 Female Placebo snus 01 1001 28JAN2008 60 Male 1002 28JAN2008 58 Male 1006 30JAN2008 58 Female 1009 06FEB2008 50 Female 1010 07FEB2008 55 Male 1012 07FEB2008 56 Male 1016 09FEB2008 53 Male
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
Treatment Site Subject Randomisation Date of Age Gender Number Number Date Birth (years) Placebo snus 01 1046 29FEB2008 32 Male 1048 03MAR2008 38 Male 1049 06MAR2008 39 Male 1205 09MAY2008 58 Female 1206 09MAY2008 47 Male 1210 13MAY2008 46 Female 1213 21MAY2008 29 Male 1214 23MAY2008 55 Male 1216 26MAY2008 55 Female 1220 03JUN2008 40 Female 1221 04JUN2008 55 Male 1222 04JUN2008 35 Female 1224 05JUN2008 42 Male 1226 06JUN2008 27 Male 1228 07JUN2008 44 Female
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
Treatment Site Subject Randomisation Date of Age Gender Number Number Date Birth (years) Placebo snus 02 1336 20APR2009 33 Female 1340 24APR2009 54 Male 1341 28APR2009 57 Female 1342 01MAY2009 33 Female 1344 01MAY2009 54 Female 1346 01MAY2009 49 Male 1348 29APR2009 37 Male 1349 29APR2009 30 Male 2001 11FEB2008 49 Female 2002 11FEB2008 36 Female 2006 18FEB2008 36 Female 2009 20FEB2008 55 Female 2010 20FEB2008 52 Female 2012 20FEB2008 47 Female 2016 21FEB2008 38 Female
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
Treatment Site Subject Randomisation Date of Age Gender Number Number Date Birth (years) Placebo snus 02 2046 10APR2008 52 Female 2048 15APR2008 47 Male 2049 18APR2008 37 Female 2206 18SEP2008 60 Female 2207 23SEP2008 27 Female 2210 26SEP2008 35 Female 2211 26SEP2008 41 Male 2212 29SEP2008 41 Female 2216 20OCT2008 52 Male 2218 22OCT2008 54 Female 2220 28OCT2008 52 Male 2221 03NOV2008 51 Female 2223 03NOV2008 31 Female 2224 03NOV2008 55 Female 2225 04NOV2008 54 Female
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
Treatment Site Subject Randomisation Date of Age Gender Number Number Date Birth (years) Placebo snus 02 2229 05NOV2008 51 Female 2232 10NOV2008 51 Female 2233 10NOV2008 51 Female 2235 21NOV2008 47 Male 2236 24NOV2008 27 Male 2237 24NOV2008 29 Female 2243 04DEC2008 42 Female 2244 04DEC2008 29 Female 2246 09DEC2008 39 Female 2249 15DEC2008 59 Female 2250 16DEC2008 53 Female 2252 16DEC2008 51 Female 2254 16DEC2008 55 Male 2256 25DEC2008 30 Female 2258 26DEC2008 49 Female
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(
Treatment Site Subject Randomisation Date of Age Gender Number Number Date Birth (years) Placebo snus 02 2259 26DEC2008 28 Male 2260 30DEC2008 43 Female 2263 21JAN2009 41 Female 2268 27JAN2009 42 Female 2269 28JAN2009 37 Male 2270 30JAN2009 60 Female 2271 30JAN2009 46 Female 2272 04FEB2009 54 Female 2274 04FEB2009 45 Female 2279 04FEB2009 39 Male 2280 04FEB2009 33 Female 2282 04FEB2009 41 Female 2283 04FEB2009 49 Female 2286 04FEB2009 29 Female 2288 05MAR2009 8 30 Male
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
Treatment Site Subject Randomisation Date of Age Gender Number Number Date Birth (years) Placebo snus 02 3016 30JUN2008 43 Female 3017 01JUL2008 45 Female 3018 01JUL2008 34 Male 3020 02JUL2008 55 Male 3022 04JUL2008 33 Female 3024 16JUL2008 39 Female 3025 31JUL2008 53 Female 3026 31JUL2008 48 Female 3027 31JUL2008 48 Male 3033 08AUG2008 57 Female 3035 12AUG2008 61 Male 3036 12AUG2008 60 Female 3037 12AUG2008 32 Female 3039 01SEP2008 26 Female 3041 09SEP2008 40 Female
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
(b) (6)
Treatment Site Subject Randomisation Date of Age Gender Number Number Date Birth (years) Placebo snus 02 3043 09SEP2008 54 Female 3046 15SEP2008 44 Male 3048 15SEP2008 45 Male 3049 17SEP2008 27 Female
(b) (6)
(b) (6)
(b) (6)
(b) (6)
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Active snus 01 1003 14 25 0 Want to quit smoking No No No 1004 19 20 1 Want to quit smoking No No No 1005 22 30 0 Want to quit smoking No No No 1007 20 20 1 Want to quit smoking No No No 1008 12 60 1 Want to quit smoking No Yes No 1011 16 60 0 Want to quit smoking No No No 1013 18 30 0 Want to quit smoking No No No 1014 16 40 0 Want to quit smoking No No No 1015 14 30 0 Want to quit smoking No No No 1019 18 25 0 Want to quit smoking No No No 1021 20 20 0 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Active snus 01 1023 17 35 0 Want to quit smoking No No No 1028 20 20 0 Want to quit smoking No No No 1029 18 40 0 Want to quit smoking No No No 1030 21 20 0 Want to quit smoking No No No 1031 19 30 1 Want to quit smoking Yes No No 1032 20 25 1 Want to quit smoking No No No 1034 16 30 1 Want to quit smoking No No No 1038 16 30 1 Want to quit smoking No No No 1040 22 30 0 Want to quit smoking No No No 1042 18 30 0 Want to quit smoking No No No 1044 12 40 0 Want to reduce smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Active snus 01 1045 18 20 1 Want to quit smoking No No No 1047 16 30 0 Want to quit smoking No No No 1050 16 35 3 Want to quit smoking No No No 1207 18 30 0 Want to quit smoking No No No 1208 17 30 0 Want to quit smoking No No No 1209 53 15 0 Want to quit smoking No No No 1211 16 30 0 Want to quit smoking No No No 1212 18 20 0 Want to quit smoking No No No 1215 20 20 0 Want to quit smoking No No No 1217 37 30 0 Want to quit smoking No No No 1218 14 30 0 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Active snus 01 1219 16 30 0 Want to quit smoking No No No 1223 20 25 0 Want to quit smoking No No No 1225 18 40 2 Want to quit smoking No No No 1227 17 25 0 Want to quit smoking No No No 1232 16 20 1 Want to quit smoking No No No 1233 34 20 1 Want to quit smoking No No No 1234 20 40 1 Want to quit smoking No No No 1235 26 20 0 Want to reduce smoking No No No 1236 14 30 0 Want to reduce smoking No No No 1238 33 15 0 Want to reduce smoking No No No 1242 20 20 0 Want to reduce smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Active snus 01 1244 17 40 0 Want to reduce smoking No No No 1246 17 60 1 Want to reduce smoking No No No 02 1327 14 30 0 Want to reduce smoking No No No 1328 19 30 0 Want to quit smoking No No No 1329 20 20 3 Want to quit smoking No No No 1331 20 20 0 Want to reduce smoking No No No 1332 14 30 0 Want to quit smoking No No No 1335 19 30 1 Want to reduce smoking No No No 1337 24 20 0 Want to quit smoking No No No 1338 16 25 0 Want to reduce smoking No No No 1339 24 25 1 Want to reduce smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Active snus 02 2015 18 25 0 Want to quit smoking No No No 2019 19 40 0 Want to quit smoking No No No 2021 16 30 0 Want to quit smoking No No No 2023 15 40 0 Want to reduce smoking No No No 2028 18 30 0 Want to quit smoking No No No 2029 18 30 1 Want to quit smoking No No No 2030 19 30 1 Want to quit smoking No No No 2031 19 15 0 Want to quit smoking No No No 2032 20 30 1 Want to quit smoking No No No 2034 35 20 5 Want to quit smoking No No No 2038 17 25 0 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Active snus 02 2040 17 20 1 Want to quit smoking No No No 2042 20 20 4 Want to quit smoking No No No 2044 20 30 0 Want to quit smoking No No No 2045 17 30 0 Want to quit smoking No No No 2047 17 20 0 Want to quit smoking No No No 2050 18 20 0 Want to quit smoking No No No 2205 15 30 2 Want to quit smoking No No No 2208 16 25 2 Want to quit smoking No No No 2209 25 20 1 Want to quit smoking No No No 2213 19 25 1 Want to reduce smoking No No No 2214 18 25 1 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Active snus 02 2215 15 30 0 Want to quit smoking No No No 2217 20 30 0 Want to quit smoking No No No 2219 25 20 0 Want to quit smoking No No No 2222 33 15 0 Want to quit smoking No No No 2226 19 40 0 Want to quit smoking No No No 2227 18 20 0 Want to reduce smoking No No No 2228 17 20 0 Want to reduce smoking No No No 2230 25 20 0 Want to reduce smoking No No No 2231 18 15 2 Want to quit smoking No No No 2234 15 60 0 Want to quit smoking No No No 2238 20 10 2 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Active snus 02 2261 18 20 1 Want to reduce smoking No No No 2262 19 15 0 Want to quit smoking No No No 2264 21 15 0 Want to quit smoking No No No 2265 15 50 0 Want to reduce smoking No No No 2266 16 20 3 Want to quit smoking No No No 2267 17 40 0 Want to quit smoking No No No 2273 20 35 0 Want to quit smoking No No No 2275 19 20 0 Want to quit smoking No No No 2276 23 30 1 Want to quit smoking No No No 2277 20 15 0 Want to quit smoking No No No 2278 18 30 0 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Active snus 02 2281 18 20 0 Want to quit smoking No No No 2284 18 30 0 Want to reduce smoking No No No 2285 19 15 0 Want to quit smoking No No No 2287 20 15 0 Want to quit smoking No No No 2289 16 60 0 Want to quit smoking No No No 2291 15 40 0 Want to quit smoking No No No 2294 17 40 0 Want to quit smoking No No No 2295 19 40 0 Want to quit smoking No No No 2296 14 20 1 Want to quit smoking No No No 2299 18 40 6 Want to quit smoking No No No 2301 20 30 0 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Active snus 02 2303 21 20 1 Want to quit smoking No No No 2306 15 40 1 Want to quit smoking No No No 3003 24 30 1 Want to quit smoking No No No 3004 20 50 2 Want to quit smoking No No No 3007 20 20 2 Want to quit smoking No No No 3008 23 20 0 Want to quit smoking No No No 3011 30 15 5 Want to quit smoking No No No 3013 19 30 1 Want to quit smoking No No No 3014 18 25 0 Want to quit smoking No No No 3015 17 50 0 Want to quit smoking No No No 3019 19 25 3 Want to reduce smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Active snus 02 3021 20 30 0 Want to quit smoking No No No 3023 20 20 0 Want to quit smoking No No No 3028 15 40 5 Want to quit smoking No No No 3029 15 30 0 Want to reduce smoking No No No 3030 20 40 0 Want to reduce smoking No No No 3031 10 20 2 Want to quit smoking No No No 3032 17 60 5 Want to quit smoking No No No 3034 17 20 3 Want to quit smoking No No No 3038 19 20 1 Want to quit smoking No No No 3040 17 40 0 Want to reduce smoking No No No 3042 18 30 0 Want to reduce smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Active snus 02 3044 20 15 0 Want to quit smoking No No No 3045 20 20 10 Want to reduce smoking No No No 3047 20 20 3 Want to quit smoking No No No 3050 19 25 1 Want to quit smoking No No No Placebo snus 01 1001 18 50 1 Want to quit smoking No No No 1002 13 30 0 Want to quit smoking No No No 1006 20 25 2 Want to quit smoking No No No 1009 20 30 0 Want to quit smoking No No No 1010 18 30 0 Want to quit smoking No No No 1012 19 40 0 Want to quit smoking No No No 1016 32 40 0 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Placebo snus 01 1017 23 30 0 Want to quit smoking No No No 1018 20 30 1 Want to quit smoking No No No 1020 21 30 0 Want to quit smoking No No No 1022 17 20 0 Want to quit smoking No No No 1024 19 30 2 Want to quit smoking No No No 1025 33 20 1 Want to quit smoking Yes No No 1026 17 40 0 Want to quit smoking No No No 1027 20 20 0 Want to quit smoking No No No 1033 20 25 1 Want to quit smoking Yes No No 1035 15 15 0 Want to quit smoking No No No 1036 15 20 0 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Placebo snus 01 1037 35 20 0 Want to quit smoking No No No 1039 18 25 1 Want to quit smoking No No No 1041 18 25 0 Want to quit smoking No No No 1043 15 20 1 Want to quit smoking No No No 1046 15 20 1 Want to quit smoking No No No 1048 20 40 0 Want to quit smoking No No No 1049 23 40 0 Want to quit smoking No No No 1205 30 30 0 Want to quit smoking No No No 1206 15 50 0 Want to reduce smoking No No No 1210 18 25 0 Want to quit smoking No No No 1213 17 30 1 Want to quit smoking No Yes No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Placebo snus 01 1214 17 40 0 Want to quit smoking No No No 1216 18 20 0 Want to quit smoking No No No 1220 18 25 0 Want to quit smoking No No No 1221 18 30 0 Want to quit smoking No No No 1222 20 30 0 Want to quit smoking No No No 1224 23 35 0 Want to quit smoking No No No 1226 15 25 0 Want to quit smoking No No No 1228 20 20 0 Want to quit smoking No No No 1229 30 20 0 Want to quit smoking No No No 1230 15 20 1 Want to reduce smoking No No No 1231 16 20 0 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Placebo snus 01 1237 21 30 0 Want to reduce smoking No No No 1239 17 25 0 Want to reduce smoking No No No 1240 17 20 0 Want to reduce smoking No No No 1241 24 20 0 Want to reduce smoking No No No 1243 18 20 0 Want to reduce smoking No No No 1245 21 20 0 Want to reduce smoking No No No 1247 19 30 0 Want to reduce smoking No No No 02 1325 15 10 2 Want to quit smoking No No No 1326 16 20 0 Want to reduce smoking No No No 1330 15 20 1 Want to quit smoking No No No 1333 17 20 4 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Placebo snus 02 1334 14 40 0 Want to reduce smoking No No No 1336 18 20 1 Want to reduce smoking No No No 1340 20 40 0 Want to reduce smoking No No No 1341 18 25 0 Want to reduce smoking No No No 1342 15 20 0 Want to reduce smoking No No No 1344 15 20 0 Want to quit smoking No No No 1346 18 20 0 Want to reduce smoking No No No 1348 19 20 0 Want to quit smoking No No No 1349 20 30 0 Want to quit smoking No No No 2001 20 20 0 Want to quit smoking No No No 2002 19 40 0 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Placebo snus 02 2006 15 20 0 Want to quit smoking No No No 2009 12 20 0 Want to quit smoking No No No 2010 17 40 0 Want to quit smoking No No No 2012 18 30 0 Want to quit smoking No No No 2016 16 30 1 Want to quit smoking No No No 2017 22 20 0 Want to quit smoking No No No 2018 21 20 0 Want to quit smoking No No No 2020 26 20 1 Want to quit smoking No No No 2022 15 40 0 Want to quit smoking No No No 2024 19 30 0 Want to quit smoking No No No 2025 20 20 0 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Placebo snus 02 2026 21 15 0 Want to quit smoking No No No 2027 19 10 0 Want to quit smoking No No No 2033 18 20 3 Want to quit smoking No No No 2035 18 60 1 Want to quit smoking No No No 2036 16 25 0 Want to quit smoking No No No 2037 18 25 1 Want to quit smoking No No No 2039 15 20 0 Want to quit smoking No No No 2041 16 25 0 Want to quit smoking No No No 2043 27 20 0 Want to quit smoking No No No 2046 17 20 3 Want to quit smoking No No No 2048 18 30 1 Want to quit smoking No Yes No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Placebo snus 02 2049 20 20 2 Want to quit smoking No No No 2206 30 20 0 Want to quit smoking No No No 2207 17 25 0 Want to reduce smoking No No No 2210 18 15 3 Want to quit smoking No No No 2211 18 40 3 Want to quit smoking No Yes No 2212 18 30 0 Want to reduce smoking No No No 2216 19 40 4 Want to reduce smoking No No No 2218 15 20 0 Want to reduce smoking No No No 2220 22 25 1 Want to reduce smoking No No No 2221 15 25 0 Want to quit smoking No No No 2223 17 10 1 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Placebo snus 02 2224 19 25 0 Want to quit smoking No No No 2225 18 20 2 Want to quit smoking No No No 2229 17 25 1 Want to reduce smoking No No No 2232 18 20 0 Want to reduce smoking No No No 2233 17 40 0 Want to quit smoking No No No 2235 16 30 0 Want to quit smoking No No No 2236 17 15 1 Want to quit smoking No No No 2237 15 20 0 Want to reduce smoking No No No 2243 15 20 0 Want to quit smoking No No No 2244 17 20 1 Want to quit smoking No No No 2246 23 20 0 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Placebo snus 02 2249 20 30 0 Want to reduce smoking No No No 2250 16 10 0 Want to quit smoking No No No 2252 18 30 0 Want to quit smoking No No No 2254 17 40 2 Want to quit smoking No No No 2256 19 20 1 Want to quit smoking No No No 2258 20 20 10 Want to quit smoking No No No 2259 18 20 0 Want to quit smoking No No No 2260 20 25 0 Want to quit smoking No No No 2263 25 40 0 Want to quit smoking No No No 2268 20 20 6 Want to quit smoking No No No 2269 17 20 0 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Placebo snus 02 2270 22 15 1 Want to quit smoking No No No 2271 22 25 0 Want to quit smoking No No No 2272 17 35 1 Want to reduce smoking No No No 2274 21 15 0 Want to quit smoking No No No 2279 14 60 1 Want to quit smoking No No No 2280 22 15 1 Want to quit smoking No No No 2282 23 30 0 Want to quit smoking No No No 2283 23 40 0 Want to quit smoking No No No 2286 17 20 1 Want to reduce smoking No No No 2288 19 20 1 Want to quit smoking No No No 2290 17 20 0 Want to reduce smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Placebo snus 02 2292 18 20 1 Want to quit smoking No No No 2293 19 20 0 Want to quit smoking No No No 2297 21 20 0 Want to quit smoking No No No 2298 17 25 0 Want to quit smoking No No No 2300 22 25 0 Want to quit smoking No No No 2302 16 20 0 Want to quit smoking No No No 2304 23 25 0 Want to quit smoking No No No 2305 25 20 0 Want to quit smoking No No No 3001 24 20 1 Want to quit smoking No No No 3002 13 20 1 Want to quit smoking No No No 3006 22 20 1 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Placebo snus 02 3009 18 40 1 Want to quit smoking No No No 3010 15 20 1 Want to quit smoking No No No 3012 14 30 6 Want to quit smoking No No Yes 3016 17 20 0 Want to quit smoking No No No 3017 17 20 0 Want to quit smoking No No No 3018 19 35 1 Want to quit smoking No No No 3020 27 35 0 Want to quit smoking No No No 3022 15 30 1 Want to quit smoking No No No 3024 16 40 0 Want to reduce smoking No No No 3025 18 30 0 Want to quit smoking No No No 3026 15 25 2 Want to quit smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.4.2 Smoking History Treatment Site Subject Age of Average Total Intention to Previous Previous Previous Number Number Initiation Number of Quit Participate NRT? Pharm. Cessation of Daily Cigarettes Attempts Aids? Aids? Smoking per Day during Past Year Placebo snus 02 3027 14 30 1 Want to quit smoking No No No 3033 15 20 1 Want to reduce smoking No No No 3035 20 30 1 Want to quit smoking No No No 3036 28 25 2 Want to quit smoking No No No 3037 18 15 1 Want to quit smoking No No No 3039 18 15 0 Want to quit smoking No No No 3041 13 30 0 Want to reduce smoking No No No 3043 27 15 0 Want to reduce smoking No No No 3046 15 40 0 Want to reduce smoking No No No 3048 13 15 1 Want to quit smoking No No No 3049 18 25 1 Want to reduce smoking No No No NRT: Nicotine Replacement Therapy Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LSH.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF page 2
Listing 16.2.5 Compliance Treatment Site Subject Visit Question Response Number Number Active snus 01 1003 Week 1 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 2 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 6 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 9 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 12 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 18 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 24 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 30 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No 1004 Week 1 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 2 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LCOMPLIANCE.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF pages 7, 8, 11, 12, 15, 18, 24, 26, 30 and 38
Listing 16.2.5 Compliance Treatment Site Subject Visit Question Response Number Number Active snus 01 1004 Week 6 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 9 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 12 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No 1005 Week 1 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 2 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 6 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 9 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 12 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 18 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 24 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LCOMPLIANCE.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF pages 7, 8, 11, 12, 15, 18, 24, 26, 30 and 38
Listing 16.2.5 Compliance Treatment Site Subject Visit Question Response Number Number Active snus 01 1005 Week 30 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 36 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No 1007 Week 1 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 2 Tried to use study products at least once a day No Used any source of nicotine other than cigarettes or snus No 1008 Week 1 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 2 Tried to use study products at least once a day No Used any source of nicotine other than cigarettes or snus No Week 6 Tried to use study products at least once a day No Used any source of nicotine other than cigarettes or snus No Week 9 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 12 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 18 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LCOMPLIANCE.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF pages 7, 8, 11, 12, 15, 18, 24, 26, 30 and 38
Listing 16.2.5 Compliance Treatment Site Subject Visit Question Response Number Number Active snus 01 1008 Week 24 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 30 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 36 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 48 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No 1011 Week 1 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 2 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 6 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 9 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 12 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 18 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LCOMPLIANCE.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF pages 7, 8, 11, 12, 15, 18, 24, 26, 30 and 38
Listing 16.2.5 Compliance Treatment Site Subject Visit Question Response Number Number Active snus 01 1011 Week 24 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No 1013 Week 1 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 2 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 6 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 9 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 12 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 18 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 24 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No 1014 Week 1 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 2 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Program path: H: \DATA \SAS \SWEDISH_MATCH_AB \SNUS \2SRT \PGM \LISTING \LCOMPLIANCE.SAS Executed: 16AUG2010, 11:57 The data presented in this Listing are contained in CRF pages 7, 8, 11, 12, 15, 18, 24, 26, 30 and 38
Listing 16.2.5 Compliance Treatment Site Subject Visit Question Response Number Number Active snus 01 1014 Week 6 Tried to use study products at least once a day No Used any source of nicotine other than cigarettes or snus No Week 9 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 12 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 18 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 24 Tried to use study products at least once a day Yes Used any source of nicotine other than cigarettes or snus No Week 48 Tried to use study products at least once a day No Used any source of nicotine other than cigarettes or snus No 1015 Week 1 Tried to use study products at least once a day Yes Used any source of nicotine o

Listing 16.2.1 Discontinued Subjects · 2014. 8. 22. · 2291 30MAR2010 Lost to Follow Up ... 1033...

Documents

Transcript of Listing 16.2.1 Discontinued Subjects · 2014. 8. 22. · 2291 30MAR2010 Lost to Follow Up ... 1033...