Publications de l’IBMM

2014 – octobre 2016

2014

(1) Morris, M. C. Spotlight on Fluorescent Biosensors-Tools for Diagnostics and Drug Discovery. Acs Medicinal Chemistry Letters 2014, 5 (2), 99-101.

(2) Hamel, A.; Sacco, M.; Mnasri, N.; Lamaty, F.; Martinez, J.; De Angelis, F.; Colacino, E.; Charnay, C. Micelles into Glycerol Solvent: Overcoming Side Reactions of Glycerol. Acs Sustainable Chemistry & Engineering 2014, 2 (6), 1353-1358.

(3) Mbang-Benet, D.-E.; Sterkers, Y.; Morelle, C.; Kebe, N.-M.; Crobu, L.; Portales, P.; Coux, O.; Hernandez, J.-F.; Meghamla, S.; Pages, M., et al. The bacterial-like HslVU protease complex subunits are involved in the control of different cell cycle events in trypanosomatids. Acta Tropica 2014, 131, 22-31.

(4) Secret, E.; Maynadier, M.; Gallud, A.; Chaix, A.; Bouffard, E.; Gary-Bobo, M.; Marcotte, N.; Mongin, O.; El Cheikh, K.; Hugues, V., et al. Two-Photon Excitation of Porphyrin-Functionalized Porous Silicon Nanoparticles for Photodynamic Therapy. Advanced Materials 2014, 26 (45), 7643-7648.

(5) Nyegue, M. A.; Ndoye-Foe, F. M. C.; Essama, R. S.; Hockmeni, T. C.; Etoa, F. X.; Menut, C. CHEMICAL COMPOSITION OF ESSENTIAL OILS OF EUGENIA CARYOPHYLLA AND MENTHA SP CF PIPERITA AND THEIR IN VITRO ANTIFUNGAL ACTIVITIES ON SIX HUMAN PATHOGENIC FUNGI. African Journal of Traditional Complementary and Alternative Medicines 2014, 11 (6), 40-46.

(6) Cottet, H.; Biron, J.-P.; Martin, M. On the optimization of operating conditions for Taylor dispersion analysis of mixtures. Analyst 2014, 139 (14), 3552-3562.

(7) Fleith, C.; Cantel, S.; Subra, G.; Mehdi, A.; Ciccione, J.; Martinez, J.; Enjalbal, C. Laser desorption ionization mass spectrometry of peptides on a hybrid CHCA organic-inorganic matrix. Analyst 2014, 139 (15), 3748-3754.

(8) Roland, A.; Bros, P.; Bouisseau, A.; Cavelier, F.; Schneider, R. Analysis of ochratoxin A in grapes, musts and wines by LC-MS/MS: First comparison of stable isotope dilution assay and diastereomeric dilution assay methods. Analytica Chimica Acta 2014, 818, 39-45.

(9) Machon, C.; Jordheim, L. P.; Puy, J.-Y.; Lefebvre, I.; Dumontet, C.; Guitton, J. Fully validated assay for the quantification of endogenous nucleoside mono- and triphosphates using online extraction coupled with liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry 2014, 406 (12), 2925-2941.

(10) Cipelletti, L.; Biron, J.-P.; Martin, M.; Cottet, H. Polydispersity Analysis of Taylor Dispersion Data: The Cumulant Method. Analytical Chemistry 2014, 86 (13), 6471-6478.

(11) Chao, S.; Romuald, C.; Fournel-Marotte, K.; Clavel, C.; Coutrot, F. A Strategy Utilizing a Recyclable Macrocycle Transporter for the Efficient Synthesis of a Triazolium-Based 2 Rotaxane. Angewandte Chemie-International Edition 2014, 53 (27), 6914-6919.

(12) de La Torre, A.; Lee, Y. Y.; Oger, C.; Sangild, P. T.; Durand, T.; Lee, J. C.-Y.; Galano, J.-M. Synthesis, Discovery, and Quantitation of Dihomo-Isofurans: Biomarkers for In Vivo Adrenic Acid Peroxidation. Angewandte Chemie-International Edition 2014, 53 (24), 6249-6252.

(13) Legrand, B.; Andre, C.; Moulat, L.; Wenger, E.; Didierjean, C.; Aubert, E.; Averlant-Petit, M. C.; Martinez, J.; Calmes, M.; Amblard, M. Unprecedented Chain-Length-Dependent Conformational Conversion Between 11/9 and 18/16 Helix in alpha/beta-Hybrid Peptides. Angewandte Chemie-International Edition 2014, 53 (48), 13131-13135.

(14) Suppo, J.-S.; Subra, G.; Berges, M.; de Figueiredo, R. M.; Campagne, J.-M. Inverse Peptide Synthesis via Activated a-Aminoesters**. Angewandte Chemie-International Edition 2014, 53 (21), 5389-5393.

(15) Wein, S.; Van Ba, C. T.; Maynadier, M.; Bordat, Y.; Perez, J.; Peyrottes, S.; Fraisse, L.; Vial, H. J. New Insight into the Mechanism of Accumulation and Intraerythrocytic Compartmentation of Albitiazolium, a New Type of Antimalarial. Antimicrobial Agents and Chemotherapy 2014, 58 (9), 5519-5527.

(16) Escande, V.; Garoux, L.; Grison, C.; Thillier, Y.; Debart, F.; Vasseur, J.-J.; Boulanger, C.; Grison, C. Ecological catalysis and phytoextraction: Symbiosis for future. Applied Catalysis B-Environmental 2014, 146, 279-288.

(17) Elayadi, H.; Smietana, M.; Vasseur, J. J.; Balzarini, J.; Lazrek, H. B. Synthesis of 1,2,3-Triazolyl Nucleoside Analogs as Potential Anti-Influenza A (H3N2 Subtype) Virus Agents. Archiv Der Pharmazie 2014, 347 (2), 134-141.

(18) El Khoury, M.; Azzouz, H.; Chavanieu, A.; Abdelmalak, N.; Chopineau, J.; Awad, M. K. Isolation and characterization of a new Bacillus thuringiensis strain Lip harboring a new cry1Aa gene highly toxic to Ephestia kuehniella (Lepidoptera: Pyralidae) larvae. Archives of Microbiology 2014, 196 (6), 435-444.

(19) Balas, L.; Guichardant, M.; Durand, T.; Lagarde, M. Confusion between protectin D1 (PD1) and its isomer protectin DX (PDX). An overview on the dihydroxy-docosatrienes described to date. Biochimie 2014, 99, 1-7.

(20) D'Ambrosio, K.; Lopez, M.; Dathan, N. A.; Ouahrani-Bettache, S.; Koehler, S.; Ascione, G.; Monti, S. M.; Winum, J.-Y.; De Simone, G. Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of L-histidinol dehydrogenase from Brucella suis. Biochimie 2014, 97, 114-120.

(21) Gerland, B.; Goudot, A.; Ligeour, C.; Pourceau, G.; Meyer, A.; Vidal, S.; Gehin, T.; Vidal, O.; Souteyrand, E.; Vasseur, J.-J., et al. Structure Binding Relationship of Galactosylated Glycoclusters toward Pseudomonas aeruginosa Lectin LecA Using a DNA-Based Carbohydrate Microarray. Bioconjugate Chemistry 2014, 25 (2), 379-392.

(22) Dutertre, S.; Benoit, E.; Molgo, J. The cone venoms on medicines. Biofutur 2014, (355), 35-40. (23) Sardo, C.; Nottelet, B.; Triolo, D.; Giammona, G.; Garric, X.; Lavigne, J.-P.; Cavallaro, G.; Coudane, J.

When Functionalization of PLA Surfaces Meets Thiol-Yne Photochemistry: Case Study with Antibacterial Polyaspartamide Derivatives. Biomacromolecules 2014, 15 (11), 4351-4362.

(24) Nasr, G.; Cristian, A.; Barboiu, M.; Vullo, D.; Winum, J.-Y.; Supuran, C. T. Carbonic anhydrase inhibitors. Inhibition of human cytosolic isoforms I and II with (reduced) Schiff's bases incorporating sulfonamide, carboxylate and carboxymethyl moieties. Bioorganic & Medicinal Chemistry 2014, 22 (10), 2867-2874.

(25) Ombouma, J.; Vullo, D.; Supuran, C. T.; Winum, J.-Y. Ferrier sulfamidoglycosylation of glycals catalyzed by nitrosonium tetrafluoroborate: Towards new carbonic anhydrase glycoinhibitors. Bioorganic & Medicinal Chemistry 2014, 22 (22), 6353-6359.

(26) Saada, M.-C.; Vullo, D.; Montero, J.-L.; Scozzafava, A.; Supuran, C. T.; Winum, J.-Y. Mono- and di-halogenated histamine, histidine and carnosine derivatives are potent carbonic anhydrase I, II, VII, XII and XIV activators. Bioorganic & Medicinal Chemistry 2014, 22 (17), 4752-4758.

(27) Kaci, M.; Uttaro, J.-P.; Lefort, V.; Mathe, C.; El Amri, C.; Perigaud, C. Synthesis of { 5-(adenin-9-yl)-2-furyl methoxy}methyl phosphonic acid and evaluations against human adenylate kinases. Bioorganic & Medicinal Chemistry Letters 2014, 24 (17), 4227-4230.

(28) Turtaut, F.; Lopez, M.; Ouahrani-Bettache, S.; Koehler, S.; Winum, J.-Y. Oxo- and thiooxo-imidazo 1,5-c pyrimidine molecule library: Beyond their interest in inhibition of Brucella suis histidinol dehydrogenase, a powerful protection tool in the synthesis of histidine analogues. Bioorganic & Medicinal Chemistry Letters 2014, 24 (21), 5008-5010.

(29) Charlier, L.; Louet, M.; Chaloin, L.; Fuchs, P.; Martinez, J.; Muriaux, D.; Favard, C.; Floquet, N. Coarse-Grained Simulations of the HIV-1 Matrix Protein Anchoring: Revisiting Its Assembly on Membrane Domains. Biophysical Journal 2014, 106 (3), 577-585.

(30) Morris, M. C.; Blondel, M. Meeting report: 3(rd) Meeting of the Biosensor Workgroup of the GDR2588. Biotechnology Journal 2014, 9 (2), 178-179.

(31) Bakarnga-Via, I.; Hzounda, J. B.; Fokou, P. V. T.; Tchokouaha, L. R. Y.; Gary-Bobo, M.; Gallud, A.; Garcia, M.; Walbadet, L.; Secka, Y.; Dongmo, P. M. J., et al. Composition and cytotoxic activity of essential oils from Xylopia aethiopica (Dunal) A. Rich, Xylopia parviflora (A. Rich) Benth.) and Monodora myristica (Gaertn) growing in Chad and Cameroon. Bmc Complementary and Alternative Medicine 2014, 14.

(32) Tilly, D.; Dayaker, G.; Bachu, P. Cobalt mediated C-H bond functionalization: emerging tools for organic synthesis. Catalysis Science & Technology 2014, 4 (9), 2756-2777.

(33) Biscans, A.; Bos, M.; Martin, A. R.; Ader, N.; Sczakiel, G.; Vasseur, J.-J.; Dupouy, C.; Debart, F. Direct Synthesis of Partially Modified 2 '-O-Pivaloyloxymethyl RNAs by a Base-Labile Protecting Group Strategy and their Potential for Prodrug-Based Gene-Silencing Applications. Chembiochem 2014, 15 (18), 2674-2679.

(34) Thi Nhu Ngoc, V.; Pellerano, M.; Lykaso, S.; Morris, M. C. Fluorescent Protein Biosensor for Probing CDK/Cyclin Activity in vitro and in Living Cells. Chembiochem 2014, 15 (15), 2298-2305.

(35) Bolognesi, M. L.; Bergamini, C.; Fato, R.; Oiry, J.; Vasseur, J.-J.; Smietana, M. Synthesis of New Lipoic Acid Conjugates and Evaluation of Their Free Radical Scavenging and Neuroprotective Activities. Chemical Biology & Drug Design 2014, 83 (6), 688-696.

(36) Abdelrahim, M. Y. M.; Tanc, M.; Winum, J.-Y.; Supuran, C. T.; Barboiu, M. Dominant behaviours in the expression of human carbonic anhydrase hCA I activity. Chemical Communications 2014, 50 (59), 8043-8046.

(37) Beaufils, D.; Danger, G.; Boiteau, L.; Rossi, J.-C.; Pascal, R. Diastereoselectivity in prebiotically relevant 5(4H)-oxazolone-mediated peptide couplings. Chemical Communications 2014, 50 (23), 3100-3102.

(38) Mouline, Z.; Mahon, E.; Gomez, E.; Barragan-Montero, V.; Montero, J.-L.; Barboiu, M. Entropy-driven lectin-recognition of multivalent glycovesicles. Chemical Communications 2014, 50 (6), 731-733.

(39) Paolantoni, D.; Rubio-Magnieto, J.; Cantel, S.; Martinez, J.; Dumy, P.; Surin, M.; Ulrich, S. Probing the importance of pi-stacking interactions in DNA-templated self-assembly of bisfunctionalized guanidinium compounds. Chemical Communications 2014, 50 (91), 14257-14260.

(40) Ulrich, S.; Dumy, P. Probing secondary interactions in biomolecular recognition by dynamic combinatorial chemistry. Chemical Communications 2014, 50 (44), 5810-5825.

(41) Akondi, K. B.; Muttenthaler, M.; Dutertre, S.; Kaas, Q.; Craik, D. J.; Lewis, R. J.; Alewood, P. F. Discovery, Synthesis, and Structure Activity Relationships of Conotoxins. Chemical Reviews 2014, 114 (11), 5815-5847.

(42) Jahn, E.; Durand, T.; Galano, J.-M.; Jahn, U. RECENT APPROACHES TO THE TOTAL SYNTHESIS OF PHYTOPROSTANES, ISOPROSTANES AND NEUROPROSTANES AS IMPORTANT PRODUCTS OF LIPID OXIDATIVE STRESS AND BIOMARKERS OF DISEASE. Chemicke Listy 2014, 108 (4), 301-319.

(43) Rakotobe, M.; Menut, C.; Andrianoelisoa, H. S.; Rahajanirina, V.; Tsy, J. M. L. P.; Rakotoarimanana, V.; Ramavovololona, P.; Danthu, P. Bark Essential Oil of Cedrelopsis grevei from Madagascar: Investigation of Steam-Distillation Conditions. Chemistry & Biodiversity 2014, 11 (2), 323-331.

(44) Croissant, J.; Salles, D.; Maynadier, M.; Mongin, O.; Hugues, V.; Banchard-Desce, M.; Cattoen, X.; Man, M. W. C.; Gallud, A.; Garcia, M., et al. Mixed Periodic Mesoporous Organosilica Nanoparticles and Core-Shell Systems, Application to in Vitro Two-Photon Imaging, Therapy, and Drug Delivery. Chemistry of Materials 2014, 26 (24), 7214-7220.

(45) Bouillon, C.; Paolantoni, D.; Rote, J. C.; Bessin, Y.; Peterson, L. W.; Dumy, P.; Ulrich, S. Degradable Hybrid Materials Based on Cationic Acylhydrazone Dynamic Covalent Polymers Promote DNA Complexation through Multivalent Interactions. Chemistry-a European Journal 2014, 20 (45), 14705-14714.

(46) Dayaker, G.; Durand, T.; Balas, L. A Versatile and Stereocontrolled Total Synthesis of Dihydroxylated Docosatrienes Containing a Conjugated E,E,Z-Triene. Chemistry-a European Journal 2014, 20 (10), 2879-2887.

(47) Guy, A.; Oger, C.; Heppekausen, J.; Signorini, C.; De Felice, C.; Fuerstner, A.; Durand, T.; Galano, J.-M. Oxygenated Metabolites of n-3 Polyunsaturated Fatty Acids as Potential Oxidative Stress Biomarkers: Total Synthesis of 8-F3t-IsoP, 10-F4t-NeuroP and D4 -10-F4t-NeuroP. Chemistry-a European Journal 2014, 20 (21), 6374-6380.

(48) Legrand, B.; Mathieu, L.; Lebrun, A.; Andriamanarivo, S.; Lisowski, V.; Masurier, N.; Zirah, S.; Kang, Y. K.; Martinez, J.; Maillard, L. T. Thiazole-Based gamma-Building Blocks as Reverse-Turn Mimetic to Design a Gramicidin S Analogue: Conformational and Biological Evaluation. Chemistry-a European Journal 2014, 20 (22), 6713-6720.

(49) Martin, C.; Legrand, B.; Lebrun, A.; Berthomieu, D.; Martinez, J.; Cavelier, F. Silaproline Helical Mimetics Selectively Form an All-trans PPII Helix. Chemistry-a European Journal 2014, 20 (44), 14240-14244.

(50) Theron, C.; Gallud, A.; Carcel, C.; Gary-Bobo, M.; Maynadier, M.; Garcia, M.; Lu, J.; Tamanoi, F.; Zink, J. I.; Man, M. W. C. Hybrid Mesoporous Silica Nanoparticles with pH-Operated and Complementary H-Bonding Caps as an Autonomous Drug-Delivery System. Chemistry-a European Journal 2014, 20 (30), 9372-9380.

(51) Topin, J.; de March, C. A.; Charlier, L.; Ronin, C.; Antonczak, S.; Golebiowski, J. Discrimination between Olfactory Receptor Agonists and Non-agonists. Chemistry-a European Journal 2014, 20 (33), 10227-10230.

(52) Ulrich, S.; Boturyn, D.; Marra, A.; Renaudet, O.; Dumy, P. Oxime Ligation: A Chemoselective Click-Type Reaction for Accessing Multifunctional Biomolecular Constructs. Chemistry-a European Journal 2014, 20 (1), 34-41.

(53) Degardin, M.; Wein, S.; Duckert, J.-F.; Maynadier, M.; Guy, A.; Durand, T.; Escale, R.; Vial, H.; Yen, V.-H. Development of the First Oral Bioprecursors of Bis-alkylguanidine Antimalarial Drugs. Chemmedchem 2014, 9 (2), 300-304.

(54) Scholz, C.; Kos, P.; Leclercq, L.; Jin, X.; Cottet, H.; Wagner, E. Correlation of Length of Linear Oligo(ethanamino) Amides with Gene Transfer and Cytotoxicity. Chemmedchem 2014, 9 (9), 2104-2110.

(55) Cecchini, M. M.; Charnay, C.; De Angelis, F.; Lamaty, F.; Martinez, J.; Colacino, E. Poly(ethylene glycol)-Based Ionic Liquids: Properties and Uses as Alternative Solvents in Organic Synthesis and Catalysis. Chemsuschem 2014, 7 (1), 45-65.

(56) Giachi, G.; Frediani, M.; Oberhauser, W.; Lamaty, F.; Martinez, J.; Colacino, E. Ultrasounds in Melted Poly( ethylene glycol) Promote Copper- Catalyzed Cyanation of Aryl Halides with K-4 Fe( CN)(6). Chemsuschem 2014, 7 (3), 919-924.

(57) Remond, E.; Juge, S. P-chirogenic organophosphorus acid-bases in asymmetric organocatalysis. Chimica Oggi-Chemistry Today 2014, 32 (4), 49-55.

(58) Morel-Salmi, C.; Julia, A.; Vigor, C.; Vercauteren, J. A Huge PVDF Adsorption Difference Between Resveratrol and epsilon-Viniferin Allows to Quantitatively Purify Them and to Assess Their Anti-Tyrosinase Property. Chromatographia 2014, 77 (13-14), 957-961.

(59) Durand, E.; Sharkawi, T.; Leclerc, G.; Raveleau, M.; van der Leest, M.; Vert, M.; Lafont, A. Head-to-Head Comparison of a Drug-Free Early Programmed Dismantling Polylactic Acid Bioresorbable Scaffold and a Metallic Stent in the Porcine Coronary Artery Six-Month Angiography and Optical Coherence Tomographic Follow-Up Study. Circulation-Cardiovascular Interventions 2014, 7 (1), 70-79.

(60) Benzaria, A.; Gracia-Julia, A.; Picart-Palmade, L.; Hue, P.; Chevalier-Lucia, D.; Marti-Mestres, G.; Hodor, N.; Dumay, E. UHPH-processed O/W submicron emulsions stabilised with a lipid-based surfactant: Physicochemical characteristics and behaviour on in vitro TC7-cell monolayers and ex vivo pig's ear skin. Colloids and Surfaces B-Biointerfaces 2014, 116, 237-246.

(61) Ortial, S.; Morandat, S.; Bortolato, M.; Roux, B.; Polidori, A.; Pucci, B.; Durand, G. PBN derived amphiphilic spin-traps. II/Study of their antioxidant properties in biomimetic membranes. Colloids and Surfaces B-Biointerfaces 2014, 113, 384-393.

(62) Chevolot, Y.; Laurenceau, E.; Phaner-Goutorbe, M.; Monnier, V.; Souteyrand, E.; Meyer, A.; Gehin, T.; Vasseur, J.-J.; Morvan, F. DNA directed immobilization glycocluster array: applications and perspectives. Current Opinion in Chemical Biology 2014, 18, 46-54.

(63) Peyrottes, S.; Caldarelli, S.; Wein, S.; Perigaud, C.; Vial, H. Exploring Prodrug Approaches for Albitiazolium and its Analogues. Current Topics in Medicinal Chemistry 2014, 14 (14), 1653-1667.

(64) Garcia, C.; Dandurand, M.; Roger, P.; Joujoux, J.-M.; Meunier, L.; Stoebner, P.-E. Macular Lymphocytic Arteritis: Three Cases Questioning Its Classification as Primary Lymphocytic Vasculitis. Dermatology 2014, 228 (2), 103-106.

(65) Canale, V.; Guzik, P.; Kurczab, R.; Verdie, P.; Satala, G.; Kubica, B.; Pawlowski, M.; Martinez, J.; Subra, G.; Bojarski, A. J., et al. Solid-supported synthesis, molecular modeling, and biological activity of long-chain arylpiperazine derivatives with cyclic amino acid amide fragments as 5-HT7 and 5-HT1A receptor ligands. European Journal of Medicinal Chemistry 2014, 78, 10-22.

(66) Gallud, A.; Vaillant, O.; Maillard, L. T.; Arama, D. P.; Dubois, J.; Maynadier, M.; Lisowski, V.; Garcia, M.; Martinez, J.; Masurier, N. Imidazopyridine-fused 1,3 -diazepinones: Synthesis and antiproliferative activity. European Journal of Medicinal Chemistry 2014, 75, 382-390.

(67) Meurillon, M.; Marton, Z.; Hospital, A.; Jordheim, L. P.; Bejaud, J.; Lionne, C.; Dumontet, C.; Perigaud, C.; Chaloin, L.; Peyrottes, S. Structure activity relationships of beta-hydroxyphosphonate nucleoside analogues as cytosolic 5 '-nucleotidase II potential inhibitors: Synthesis, in vitro evaluation and molecular modeling studies. European Journal of Medicinal Chemistry 2014, 77, 18-37.

(68) Prevel, C.; Kurzawa, L.; Thi Nhu Ngoc, V.; Morris, M. C. Fluorescent biosensors for drug discovery new tools for old targets - Screening for inhibitors of cyclin-dependent kinases. European Journal of Medicinal Chemistry 2014, 88, 74-88.

(69) Crauste, C.; Vigor, C.; Brabet, P.; Picq, M.; Lagarde, M.; Hamel, C.; Durand, T.; Vercauteren, J. Synthesis and Evaluation of Polyunsaturated Fatty Acid-Phenol Conjugates as Anti-Carbonyl-Stress Lipophenols. European Journal of Organic Chemistry 2014, (21), 4548-4561.

(70) Dayde, B.; Pierra, C.; Gosselin, G.; Surleraux, D.; Ilagouma, A. T.; Laborde, C.; Volle, J.-N.; Virieux, D.; Pirat, J.-L. Synthesis of Unnatural Phosphonosugar Analogues. European Journal of Organic Chemistry 2014, 2014 (6), 1333-1337.

(71) Dondoni, A.; Marra, A. Metal-Catalyzed and Metal-Free Alkyne Hydrothiolation: Synthetic Aspects and Application Trends. European Journal of Organic Chemistry 2014, (19), 3955-3969.

(72) Ligeour, C.; Dupin, L.; Marra, A.; Vergoten, G.; Meyer, A.; Dondoni, A.; Souteyrand, E.; Vasseur, J.-J.; Chevolot, Y.; Morvan, F. Synthesis of Galactoclusters by Metal-Free Thiol "Click Chemistry" and Their Binding Affinities for Pseudomonas aeruginosa Lectin LecA. European Journal of Organic Chemistry 2014, (34), 7621-7630.

(73) Rene, A.; Martinez, J.; Cavelier, F. N-Substituted Glycines with Functional Side-Chains for Peptoid Synthesis. European Journal of Organic Chemistry 2014, (36), 8142-8147.

(74) Sameza, M. L.; Boat, M. A. B.; Nguemezi, S. T.; Mabou, L. C. N.; Dongmo, P. M. J.; Boyom, F. F.; Menut, C. Potential use of Eucalyptus globulus essential oil against Phytophthora colocasiae the causal agent of taro leaf blight. European Journal of Plant Pathology 2014, 140 (2), 243-250.

(75) Minghetti, L.; Salvi, R.; Salvatori, M. L.; Ajmone-Cat, M. A.; De Nuccio, C.; Visentin, S.; Bultel-Ponce, V.; Oger, C.; Guy, A.; Galano, J.-M., et al. Nonenzymatic oxygenated metabolites of alpha-linolenic acid B-1- and L-1-phytoprostanes protect immature neurons from oxidant injury and promote differentiation of oligodendrocyte progenitors through PPAR-gamma activation. Free Radical Biology and Medicine 2014, 73, 41-50.

(76) Youl, E.; Magous, R.; Cros, G.; Oiry, C. MAP Kinase cross talks in oxidative stress-induced impairment of insulin secretion. Involvement in the protective activity of quercetin. Fundamental & Clinical Pharmacology 2014, 28 (6), 608-615.

(77) Dutertre, S. Venomics in medicinal chemistry Foreword. Future Medicinal Chemistry 2014, 6 (15), 1609-1610.

(78) Prashanth, J. R.; Brust, A.; Jin, A.-H.; Alewood, P. F.; Dutertre, S.; Lewis, R. J. Cone snail venomics: from novel biology to novel therapeutics. Future Medicinal Chemistry 2014, 6 (15), 1659-1675.

(79) Kadri, N.; Khettal, B.; Adjebli, A.; Cresteil, T.; Yahiaoui-Zaidi, R.; Barragan-Montero, V.; Montero, J.-L. Antiangiogenic activity of neutral lipids, glycolipids, and phospholipids fractions of Pinus halepensis Mill. seeds. Industrial Crops and Products 2014, 54, 6-12.

(80) Hu, Y.; Darcos, V.; Monge, S.; Li, S.; Zhou, Y.; Su, F. Thermo-responsive release of curcumin from micelles prepared by self-assembly of amphiphilic P(NIPAAm-co-DMAAm)-b-PLLA-b-P (NIPAAm-co-DMAAm) triblock copolymers. International Journal of Pharmaceutics 2014, 476 (1-2), 31-40.

(81) Mouri, A.; Diat, O.; Lerner, D. A.; El Ghzaoui, A.; Ajovalasit, A.; Dorandeu, C.; Maurel, J.-C.; Devoisselle, J.-M.; Legrand, P. Water solubilization capacity of pharmaceutical microemulsions based on Peceol (R), lecithin and ethanol. International Journal of Pharmaceutics 2014, 475 (1-2), 324-334.

(82) Tousch, D.; Bidel, L. P. R.; Cazals, G.; Ferrare, K.; Leroy, J.; Faucanie, M.; Chevassus, H.; Tournier, M.; Lajoix, A.-D.; Azay-Milhau, J. Chemical Analysis and Antihyperglycemic Activity of an Original Extract from Burdock Root (Arctium lappa). Journal of Agricultural and Food Chemistry 2014, 62 (31), 7738-7745.

(83) Lorion, C.; Faye, C.; Maret, B.; Trimaille, T.; Regnier, T.; Sommer, P.; Debret, R. Biosynthetic support based on dendritic poly(L-lysine) improves human skin fibroblasts attachment. Journal of Biomaterials Science-Polymer Edition 2014, 25 (2), 136-149.

(84) Chamieh, J.; Koval, D.; Besson, A.; Kasicka, V.; Cottet, H. Generalized polymer effective charge measurement by capillary isotachophoresis. Journal of Chromatography A 2014, 1370, 255-262.

(85) Vigor, C.; Bertrand-Michel, J.; Pinot, E.; Oger, C.; Vercauteren, J.; Le Faouder, P.; Galano, J.-M.; Lee, J. C.-Y.; Durand, T. Non-enzymatic lipid oxidation products in biological systems: Assessment of the metabolites from polyunsaturated fatty acids. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences 2014, 964, 65-78.

(86) Mouri, A.; Diat, O.; El Ghzaoui, A.; Bauer, C.; Maurel, J. C.; Devoisselle, J.-M.; Dorandeu, C.; Legrand, P. Phase behavior of reverse microemulsions based on Peceol (R). Journal of Colloid and Interface Science 2014, 416, 139-146.

(87) Boustta, M.; Colombo, P.-E.; Lenglet, S.; Poujol, S.; Vert, M. Versatile UCST-based thermoresponsive hydrogels for loco- regional sustained drug delivery. Journal of Controlled Release 2014, 174, 1-6.

(88) Oukacine, F.; Bernard, S.; Bobe, I.; Cottet, H. Physico-chemical characterization of polymeric micelles loaded with platinum derivatives by capillary electrophoresis and related methods. Journal of Controlled Release 2014, 196, 139-145.

(89) Hanif, M.; Chohan, Z. H.; Winum, J.-Y.; Akhtar, J. Metal-based carboxamide-derived compounds endowed with antibacterial and antifungal activity. Journal of Enzyme Inhibition and Medicinal Chemistry 2014, 29 (4), 517-526.

(90) Nyegue, M. A.; Ndoye-Foe, F.; Etoa, F.-X.; Zollo, P.-H. A.; Menut, C. Study of Chemical Composition, Growth Inhibition and Antigerminative Effect of Three Essential Oils from Cameroon on Four Bacillus strains. Journal of Essential Oil Bearing Plants 2014, 17 (6), 1335-1342.

(91) Hu, Y.; Darcos, V.; Monge, S.; Li, S.; Zhou, Y.; Su, F. Tunable thermo-responsive P(NIPAAm-co-DMAAm)-b-PLLA-b-P(NIPAAm-co-DMAAm) triblock copolymer micelles as drug carriers. Journal of Materials Chemistry B 2014, 2 (18), 2738-2748.

(92) Jouannin, C.; Tourne-Peteilh, C.; Darcos, V.; Sharkawi, T.; Devoisselle, J.-M.; Gaveau, P.; Dieudonne, P.; Vioux, A.; Viau, L. Drug delivery systems based on pharmaceutically active ionic liquids and biocompatible poly(lactic acid). Journal of Materials Chemistry B 2014, 2 (20), 3133-3141.

(93) Misra, S. K.; Kondaiah, P.; Bhattacharya, S.; Boturyn, D.; Dumy, P. Co-liposomes comprising a lipidated multivalent RGD-peptide and a cationic gemini cholesterol induce selective gene transfection in alpha v beta 3 and alpha v beta 5 integrin receptor-rich cancer cells. Journal of Materials Chemistry B 2014, 2 (35), 5758-5767.

(94) Ferrandez, Y.; Dezi, M.; Bosco, M.; Urvoas, A.; Valerio-Lepiniec, M.; Le Bon, C.; Giusti, F.; Broutin, I.; Durand, G.; Polidori, A., et al. Amphipol-Mediated Screening of Molecular Orthoses Specific for Membrane Protein Targets. Journal of Membrane Biology 2014, 247 (9-10), 925-940.

(95) Mary, S.; Damian, M.; Rahmeh, R.; Mouillac, B.; Marie, J.; Granier, S.; Baneres, J.-L. Amphipols in G Protein-Coupled Receptor Pharmacology: What Are They Good For? Journal of Membrane Biology 2014, 247 (9-10), 853-860.

(96) Opacic, M.; Durand, G.; Bosco, M.; Polidori, A.; Popot, J.-L. Amphipols and Photosynthetic Light-Harvesting Pigment-Protein Complexes. Journal of Membrane Biology 2014, 247 (9-10), 1031-1041.

(97) Planchard, N.; Point, E.; Dahmane, T.; Giusti, F.; Renault, M.; Le Bon, C.; Durand, G.; Milon, A.; Guittet, E.; Zoonens, M., et al. The Use of Amphipols for Solution NMR Studies of Membrane Proteins: Advantages and Constraints as Compared to Other Solubilizing Media. Journal of Membrane Biology 2014, 247 (9-10), 827-842.

(98) Chatalic, K. L. S.; Franssen, G. M.; van Weerden, W. M.; McBride, W. J.; Laverman, P.; de Blois, E.; Hajjaj, B.; Brunel, L.; Goldenberg, D. M.; Fehrentz, J.-A., et al. Preclinical Comparison of (AlF)-F-18- and Ga-68-Labeled Gastrin-Releasing Peptide Receptor Antagonists for PET Imaging of Prostate Cancer. Journal of Nuclear Medicine 2014, 55 (12), 2050-2056.

(99) Dayaker, G.; Durand, T.; Balas, L. Total Synthesis of Neuroprotectin D1 Analogues Derived from Omega-6 Docosapentaenoic Acid (DPA) and Adrenic Acid (AdA) from a Common Pivotal, Late-Stage Intermediate. Journal of Organic Chemistry 2014, 79 (6), 2657-2665.

(100) Konnert, L.; Lamaty, F.; Martinez, J.; Colacino, E. Solventless Mechanosynthesis of N-Protected Amino Esters. Journal of Organic Chemistry 2014, 79 (9), 4008-4017.

(101) Konnert, L.; Reneaud, B.; de Figueiredo, R. M.; Campagne, J.-M.; Lamaty, F.; Martinez, J.; Colacino, E. Mechanochemical Preparation of Hydantoins from Amino Esters: Application to the Synthesis of the Antiepileptic Drug Phenytoin. Journal of Organic Chemistry 2014, 79 (21), 10132-10142.

(102) Rosselin, M.; Choteau, F.; Zeamari, K.; Nash, K. M.; Das, A.; Lauricella, R.; Lojou, E.; Tuccio, B.; Villamena, F. A.; Durand, G. Reactivities of Substituted alpha-Phenyl-N-tert-butyl Nitrones. Journal of Organic Chemistry 2014, 79 (14), 6615-6626.

(103) Lafaille, F.; Solassol, I.; Enjalbal, C.; Bertrand, B.; Doulain, P.-E.; Vappiani, J.; Bonnet, P.-A.; Deleuze-Masquefa, C.; Bressolle, F. M. M. Structural characterization of in vitro metabolites of the new anticancer agent EAPB0503 by liquid chromatography-tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 2014, 88, 429-440.

(104) Ghirardello, M.; Oberg, K.; Staderini, S.; Renaudet, O.; Berthet, N.; Dumy, P.; Hed, Y.; Marra, A.; Malkoch, M.; Dondoni, A. Thiol-Ene and Thiol-Yne-Based Synthesis of Glycodendrimers as Nanomolar Inhibitors of Wheat Germ Agglutinin. Journal of Polymer Science Part a-Polymer Chemistry 2014, 52 (17), 2422-2433.

(105) Boyer, J.-B.; Dedieu, A.; Armengaud, J.; Verdie, P.; Subra, G.; Martinez, J.; Enjalbal, C. N- and O-acetylation of threonine residues in the context of proteomics. Journal of Proteomics 2014, 108, 369-372.

(106) Samide, A.; Rotaru, P.; Ionescu, C.; Tutunaru, B.; Moanta, A.; Barragan-Montero, V. Thermal behaviour and adsorption properties of some benzothiazole derivatives. Journal of Thermal Analysis and Calorimetry 2014, 118 (2), 651-659.

(107) Brun, J.-F.; Varlet-Marie, E.; Chevance, G.; Pollatz, M.; Fedou, C.; de Mauverger, E. R. Versatility of 'hemorheologic fitness' according to exercise intensity: emphasis on the "healthy primitive lifestyle". Korea-Australia Rheology Journal 2014, 26 (2), 249-253.

(108) Sisavath, N.; Le Saux, T.; Leclercq, L.; Cottet, H. Effect of Dendrimer Generation on the Interactions between Human Serum Albumin and Dendrigraft Polylysines. Langmuir 2014, 30 (15), 4450-4457.

(109) Yakushev, A. A.; Averin, A. D.; Anokhin, M. V.; Maloshitskaya, O. A.; Lamaty, F.; Beletskaya, I. P. Copper-Catalyzed Amination in the Synthesis of Polyoxadiamine Derivatives of Aza- and Diazacrown Ethers. Macroheterocycles 2014, 7 (4), 358-364.

(110) Beuille, E.; Darcos, V.; Coudane, J.; Lacroix-Desmazes, P.; Nottelet, B. Regioselective Halogenation of Poly(lactide) by Free-Radical Process. Macromolecular Reaction Engineering 2014, 8 (2), 141-148.

(111) Sharkawi, T.; Ruiz, E.; Cacciaguerra, T.; Domurado, M.; Bataille, B. Preliminary Investigation of Improved Solubility of Nifedipine by Co Processing with Vinylcaprolactam/Vinylacetate/PEG(6000) copolymer Through Spray Dried Solid Dispersions. Macromolecular Symposia 2014, 336 (1), 47-52.

(112) Boustta, M.; Leclercq, L.; Vert, M.; Vasilevskaya, V. V. Experimental and Theoretical Studies of Polyanion-Polycation Complexation in Salted Media in the Context of Nonviral Gene Transfection. Macromolecules 2014, 47 (11), 3574-3581.

(113) Jin, X.; Leclercq, L.; Sisavath, N.; Cottet, H. Investigating the Influence of Phosphate Ions on Poly(L-lysine) Conformations by Taylor Dispersion Analysis. Macromolecules 2014, 47 (15), 5320-5327.

(114) Franconi, F.; Roux, J.; Garric, X.; Lemaire, L. Early Postsurgical Visualization of Composite Mesh Used in Ventral Hernia Repair by Amide Proton Transfer MRI. Magnetic Resonance in Medicine 2014, 71 (1), 313-317.

(115) Maffei, S.; De Felice, C.; Cannarile, P.; Leoncini, S.; Signorini, C.; Pecorelli, A.; Montomoli, B.; Lunghetti, S.; Ciccoli, L.; Durand, T., et al. Effects of omega-3 PUFAs Supplementation on Myocardial Function and Oxidative Stress Markers in Typical Rett Syndrome. Mediators of Inflammation 2014.

(116) De Felice, C.; Signorini, C.; Leoncini, S.; Pecorelli, A.; Durand, T.; Valacchi, G.; Ciccoli, L.; Hayek, J. OXIDATIVE STRESS AND RETT SYNDROME. Minerva Pediatrica 2014, 66 (1), 41-62.

(117) Holubova, M.; Nagelova, V.; Lacinova, Z.; Haluzik, M.; Sykora, D.; Moulin, A.; Blayo, A. L.; Fehrentz, J. A.; Martinez, J.; Stofkova, A., et al. Triazole GHS-R1a antagonists JMV4208 and JMV3002 attenuate food intake, body weight, and adipose tissue mass in mice. Molecular and Cellular Endocrinology 2014, 393 (1-2), 120-128.

(118) Combemale, S.; Assam-Evoung, J.-N.; Houaidji, S.; Bibi, R.; Barragan-Montero, V. Gold Nanoparticles Decorated with Mannose-6-phosphate Analogues. Molecules 2014, 19 (1), 1120-1149.

(119) Perrier, M.; Busson, M.; Massasso, G.; Long, J.; Boudousq, V.; Pouget, J. P.; Peyrottes, S.; Perigaud, C.; Porredon-Guarch, C.; de Lapuente, J., et al. Tl-201(+)-labelled Prussian blue nanoparticles as contrast agents for SPECT scintigraphy. Nanoscale 2014, 6 (22), 13425-13429.

(120) Noudogbessi, J.-P.; Gary-Bobo, M.; Adomou, A.; Adjalian, E.; Alitonou, G. A.; Avlessi, F.; Garcia, M.; Sohounhloue, D. C. K.; Menut, C. Comparative Chemical Study and Cytotoxic Activity of Uvariodendron angustifolium Essential Oils from Benin. Natural Product Communications 2014, 9 (2), 261-264.

(121) Dutertre, S.; Jin, A.-H.; Vetter, I.; Hamilton, B.; Sunagar, K.; Lavergne, V.; Dutertre, V.; Fry, B. G.; Antunes, A.; Venter, D. J., et al. Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails. Nature Communications 2014, 5.

(122) Giganti, D.; Bouillon, A.; Tawk, L.; Robert, F.; Martinez, M.; Crublet, E.; Weber, P.; Girard-Blanc, C.; Petres, S.; Haouz, A., et al. A novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilase. Nature Communications 2014, 5.

(123) De Felice, C.; Della Ragione, F.; Signorini, C.; Leoncini, S.; Pecorelli, A.; Ciccoli, L.; Scalabri, F.; Marracino, F.; Madonna, M.; Belmonte, G., et al. Oxidative brain damage in Mecp2-mutant murine models of Rett syndrome. Neurobiology of Disease 2014, 68, 66-77.

(124) Jamil, J.; Bankhele, P.; Salvi, A.; Mannix, J. E.; Oger, C.; Guy, A.; Galano, J.-M.; Durand, T.; Njie-Mbye, Y. F.; Ohia, S. E., et al. Role of the Non-enzymatic Metabolite of Eicosapentaenoic Acid, 5-epi-5-F-3t-Isoprostane in the Regulation of H-3 D-Aspartate Release in Isolated Bovine Retina. Neurochemical Research 2014, 39 (12), 2360-2369.

(125) Cecchini, M. M.; Bendjeriou, A.; Mnasri, N.; Charnay, C.; De Angelis, F.; Lamaty, F.; Martinez, J.; Colacino, E. Synthesis of novel multi-cationic PEG-based ionic liquids. New Journal of Chemistry 2014, 38 (12), 6133-6138.

(126) Kasthuri, M.; El Amri, C.; Lefort, V.; Perigaud, C.; Peyrottes, S. Synthesis and study of (R)- and (S)-beta-hydroxyphosphonate acyclonucleosides as structural analogues of (S)-HPMPC (cidofovir). New Journal of Chemistry 2014, 38 (10), 4736-4742.

(127) Casoni, F.; Dupin, L.; Vergoten, G.; Meyer, A.; Ligeour, C.; Gehin, T.; Vidal, O.; Souteyrand, E.; Vasseur, J.-J.; Chevolot, Y., et al. The influence of the aromatic aglycon of galactoclusters on the binding of LecA: a case study with O-phenyl, S-phenyl, O-benzyl, S-benzyl, O-biphenyl and O-naphthyl aglycons. Organic & Biomolecular Chemistry 2014, 12 (45), 9166-9179.

(128) Signorini, C.; Leoncini, S.; De Felice, C.; Pecorelli, A.; Meloni, I.; Ariani, F.; Mari, F.; Amabile, S.; Paccagnini, E.; Gentile, M., et al. Redox Imbalance and Morphological Changes in Skin Fibroblasts in Typical Rett Syndrome. Oxidative Medicine and Cellular Longevity 2014.

(129) Nieves-Cordones, M.; Chavanieu, A.; Jeanguenin, L.; Alcon, C.; Szponarski, W.; Estaran, S.; Cherel, I.; Zimmermann, S.; Sentenac, H.; Gaillard, I. Distinct Amino Acids in the C-Linker Domain of the Arabidopsis K+ Channel KAT2 Determine Its Subcellular Localization and Activity at the Plasma Membrane. Plant Physiology 2014, 164 (3), 1415-1429.

(130) Gladine, C.; Newman, J. W.; Durand, T.; Pedersen, T. L.; Galano, J.-M.; Demougeot, C.; Berdeaux, O.; Pujos-Guillot, E.; Mazur, A.; Comte, B. Lipid Profiling following Intake of the Omega 3 Fatty Acid DHA Identifies the Peroxidized Metabolites F-4-Neuroprostanes as the Best Predictors of Atherosclerosis Prevention. Plos One 2014, 9 (2).

(131) Logez, C.; Berger, S.; Legros, C.; Baneres, J.-L.; Cohen, W.; Delagrange, P.; Nosjean, O.; Boutin, J. A.; Ferry, G.; Simonin, F., et al. Recombinant Human Melatonin Receptor MT1 Isolated in Mixed Detergents Shows Pharmacology Similar to That in Mammalian Cell Membranes. Plos One 2014, 9 (6).

(132) Penarete-Vargas, D. M.; Boisson, A.; Urbach, S.; Chantelauze, H.; Peyrottes, S.; Fraisse, L.; Vial, H. J. A Chemical Proteomics Approach for the Search of Pharmacological Targets of the Antimalarial Clinical Candidate Albitiazolium in Plasmodium falciparum Using Photocrosslinking and Click Chemistry. Plos One 2014, 9 (12).

(133) Rideau Batista Novais, A.; Crouzin, N.; Cavalier, M.; Boubal, M.; Guiramand, J.; Cohen-Solal, C.; Ferreira, M.-C. d. J.; Cambonie, G.; Vignes, M.; Barbanel, G. Tiagabine Improves Hippocampal Long-Term Depression in Rat Pups Subjected to Prenatal Inflammation. Plos One 2014, 9 (9).

(134) Signorini, C.; De Felice, C.; Leoncini, S.; Durand, T.; Galano, J.-M.; Cortelazzo, A.; Zollo, G.; Guerranti, R.; Gonnelli, S.; Caffarelli, C., et al. Altered erythrocyte membrane fatty acid profile in typical Rett syndrome: Effects of omega-3 polyunsaturated fatty acid supplementation. Prostaglandins Leukotrienes and Essential Fatty Acids 2014, 91 (5), 183-193.

(135) Leroy, A.; Al Samad, A.; Garric, X.; Hunger, S.; Noel, D.; Coudane, J.; Nottelet, B. Biodegradable networks for soft tissue engineering by thiol-yne photo cross-linking of multifunctional polyesters. Rsc Advances 2014, 4 (60), 32017-32023.

(136) Maret, B.; Regnier, T.; Rossi, J.-C.; Garrelly, L.; Vial, L.; Pascal, R. Reduction with tris(2-carboxyethyl)phosphine (TCEP) enables the use of an S-sulphonate protecting group for thiol-mediated bioconjugation. Rsc Advances 2014, 4 (15), 7725-7728.

(137) Warther, D.; Jimenez, C. M.; Raehm, L.; Gerardin, C.; Durand, J.-O.; Morere, A.; El Cheikh, K.; Gallud, A.; Gary-Bobo, M.; Maynadier, M., et al. Small sized mesoporous silica nanoparticles functionalized with mannose for retinoblastoma cell imaging. Rsc Advances 2014, 4 (70), 37171-37179.

(138) Liu, Z.; Beaufils, D.; Rossi, J.-C.; Pascal, R. Evolutionary Importance of the Intramolecular Pathways of Hydrolysis of Phosphate Ester Mixed Anhydrides with Amino Acids and Peptides. Scientific Reports 2014, 4.

(139) Croissant, J.; Chaix, A.; Mongin, O.; Wang, M.; Clement, S.; Raehm, L.; Durand, J.-O.; Hugues, V.; Blanchard-Desce, M.; Maynadier, M., et al. Two-Photon-Triggered Drug Delivery via Fluorescent Nanovalves. Small 2014, 10 (9), 1752-1755.

(140) Chaubet, G.; Cazals, G.; Lebrun, A.; Martinez, J.; Parrot, I. From Diketopiperazines to Hydantoins: An Unprecedented Rearrangement. Synlett 2014, 25 (4), 574-578.

(141) Ortial, S.; Dave, R.; Benfodda, Z.; Benimelis, D.; Meffre, P. Synthesis of cis-5-Trifluoromethylproline from L-Glutamic Acid. Synlett 2014, 25 (4), 569-573.

(142) Bantreil, X.; Kanfar, N.; Gehin, N.; Golliard, E.; Ohlmann, P.; Martinez, J.; Lamaty, F. Iron-catalyzed benzamide formation. Application to the synthesis of moclobemide. Tetrahedron 2014, 70 (34), 5093-5099.

(143) Barbeyron, R.; Benedetti, E.; Cossy, J.; Vasseur, J.-J.; Arseniyadis, S.; Smietana, M. Recent developments in alkyne borylations. Tetrahedron 2014, 70 (45), 8431-8452.

(144) El Kharrat, S.; Laurent, P.; Blancou, H. Synthesis of substituted 1-trifluoromethyl and 1-perfluoroalky1-3-(arylamino)prop-2-en-1-one: advances in the mechanism of Combes 2-trifluoromethyl and 2-perfluoroalkyl quinolines synthesis. Tetrahedron 2014, 70 (6), 1252-1266.

(145) Malcor, J.-D.; Brouillette, Y.; Graffion, J.; Spielmann, K.; Masurier, N.; Maillard, L. T.; Martinez, J.; Lisowski, V. Synthesis and reactivity of pyrrolo 3,2-d 1,3 oxazine-2,4-dione. Access to new pyrrolo 3,2-e 1,4 diazepine-2,5-diones. Tetrahedron 2014, 70 (31), 4631-4639.

(146) Marra, A.; Zelli, R.; D'Orazio, G.; La Ferla, B.; Dondoni, A. Synthesis and glycosidase inhibition properties of triazole-linked calixarene-iminosugar clusters. Tetrahedron 2014, 70 (49), 9387-9393.

(147) Dayde, B.; Pierra, C.; Gosselin, G.; Surleraux, D.; Ilagouma, A. T.; Van der Lee, A.; Voile, J.-N.; Virieux, D.; Pirat, J.-L. Synthesis of unnatural 2-and 3-deoxyfuranose analogues. Tetrahedron Letters 2014, 55 (27), 3706-3708.

(148) Dayde, B.; Pierra, C.; Gosselin, G.; Surleraux, D.; Ilagouma, A. T.; Volle, J.-N.; Virieux, D.; Pirat, J.-L. Synthesis of unnatural 3 '-phospha-2 '-deoxyfuranose nucleoside analogues. Tetrahedron Letters 2014, 55 (46), 6328-6330.

(149) Ghezal, S.; Thomasson, M. S.; Lefebvre-Tournier, I.; Perigaud, C.; Macnaughtan, M. A.; Roy, B. CDP-Ethanolamine and CDP-Choline: one-pot synthesis and P-31 NMR study. Tetrahedron Letters 2014, 55 (38), 5306-5310.

(150) Sebih, F.; Bellahouel, S.; Rolland, M.; Derdour, A.; Martinez, J.; Rolland, V. Diastereospecific synthesis of new 4-substituted L-theanine derivatives. Tetrahedron-Asymmetry 2014, 25 (8), 690-696.

(151) Dutertre, S.; Jin, A.-H.; Alewood, P. F.; Lewis, R. J. Intraspecific variations in Conus geographus defence-evoked venom and estimation of the human lethal dose. Toxicon 2014, 91, 135-144.

2015

(1) Barciszewski, J.; Marquez, V. E.; Vasseur, J.-J.; Markiewicz, W. T. Chemical Biology of Nucleic Acids. Acs Chemical Biology 2015, 10 (6), 1358-1361.

(2) Ombouma, J.; Vullo, D.; Dumy, P.; Supuran, C. T.; Winum, J.-Y. Carbonic Anhydrase Glycoinhibitors belonging to the Aminoxysulfonamide Series. Acs Medicinal Chemistry Letters 2015, 6 (7), 819-821.

(3) Lanzillotto, M.; Konnert, L.; Lamaty, F.; Martinez, J.; Colacino, E. Mechanochemical 1,1 '-Carbonyldiimidazole-Mediated Synthesis of Carbamates. Acs Sustainable Chemistry & Engineering 2015, 3 (11), 2882-2889.

(4) Mnasri, N.; Nyalosaso, J. L.; Colacino, E.; Derrien, G.; Lamaty, F.; Martinez, J.; Zajac, J.; Charnay, C. Copper-Containing Rod-Shaped Nanosized Silica Particles for Microwave-Assisted Synthesis of Triazoles in Aqueous Solution. Acs Sustainable Chemistry & Engineering 2015, 3 (10), 2516-2525.

(5) Wenger, E.; Moulat, L.; Legrand, B.; Amblard, M.; Calmes, M.; Didierjean, C. Crystal structure of Boc-(S)-ABOC-(S)-Ala-(S)ABOC-(S)-Phe-OBn chloroform monosolvate. Acta Crystallographica Section E-Crystallographic Communications 2015, 71, 1193-+.

(6) Dahani, M.; Barret, L.-A.; Raynal, S.; Jungas, C.; Pernot, P.; Polidori, A.; Bonnete, F. Use of dynamic light scattering and small-angle X-ray scattering to characterize new surfactants in solution conditions for membrane-protein crystallization. Acta Crystallographica Section F-Structural Biology Communications 2015, 71, 838-846.

(7) Benfodda, Z.; Benimelis, D.; Jean, M.; Naubron, J. V.; Rolland, V.; Meffre, P. Synthesis, resolution, and determination of absolute configuration of protected alpha-ethynylphenylalanine enantiomers. Amino Acids 2015, 47 (5), 899-907.

(8) Benfodda, Z.; Benimelis, D.; Reginato, G.; Meffre, P. Ethynylglycine synthon, a useful precursor for the synthesis of biologically active compounds: an update Part I: preparations of ethynylglycine synthon. Amino Acids 2015, 47 (2), 271-279.

(9) Fanelli, R.; Jeanne-Julien, L.; Rene, A.; Martinez, J.; Cavelier, F. Stereoselective synthesis of unsaturated alpha-amino acids. Amino Acids 2015, 47 (6), 1107-1115.

(10) Jordheim, L. P.; Puy, J.-Y.; Cros-Perrial, E.; Peyrottes, S.; Lefebvre, I.; Perigaud, C.; Dumontet, C. Determination of the enzymatic activity of cytosolic 5 '-nucleotidase cN-II in cancer cells: development of a simple analytical method and related cell line models. Analytical and Bioanalytical Chemistry 2015, 407 (19), 5747-5758.

(11) Milic, I.; Griesser, E.; Vemula, V.; Ieda, N.; Nakagawa, H.; Miyata, N.; Galano, J.-M.; Oger, C.; Durand, T.; Fedorova, M. Profiling and relative quantification of multiply nitrated and oxidized fatty acids. Analytical and Bioanalytical Chemistry 2015, 407 (19), 5587-5602.

(12) Rodriguez, A. M.; Dutertre, S.; Lewis, R. J.; Mari, F. Intraspecific variations in Conus purpurascens injected venom using LC/MALDI-TOF-MS and LC-ESI-TripleTOF-MS. Analytical and Bioanalytical Chemistry 2015, 407 (20), 6105-6116.

(13) Chamieh, J.; Martin, M.; Cottet, H. Quantitative Analysis in Capillary Electrophoresis: Transformation of Raw Electropherograms into Continuous Distributions. Analytical Chemistry 2015, 87 (2), 1050-1057.

(14) Cipelletti, L.; Biron, J.-P.; Martin, M.; Cottet, H. Measuring Arbitrary Diffusion Coefficient Distributions of Nano-Objects by Taylor Dispersion Analysis. Analytical Chemistry 2015, 87 (16), 8489-8496.

(15) Jonasdottir, H. S.; Papan, C.; Fabritz, S.; Balas, L.; Durand, T.; Hardardottir, I.; Freysdottir, J.; Giera, M. Differential Mobility Separation of Leukotrienes and Protectins. Analytical Chemistry 2015, 87 (10), 5036-5040.

(16) Sisavath, N.; Got, P.; Charriere, G. M.; Destournieux-Garzon, D.; Cottet, H. Taking Advantage of Electric Field Induced Bacterial Aggregation for the Study of Interactions between Bacteria and Macromolecules by Capillary Electrophoresis. Analytical Chemistry 2015, 87 (13), 6761-6768.

(17) Bartolami, E.; Bessin, Y.; Gervais, V.; Dumy, P.; Ulrich, S. Dynamic Expression of DNA Complexation with Self-assembled Biomolecular Clusters. Angewandte Chemie-International Edition 2015, 54 (35), 10183-10187.

(18) Frotscher, E.; Danielczak, B.; Vargas, C.; Meister, A.; Durand, G.; Keller, S. A Fluorinated Detergent for Membrane-Protein Applications. Angewandte Chemie-International Edition 2015, 54 (17), 5069-5073.

(19) Jebors, S.; Ciccione, J.; Al-Halifa, S.; Nottelet, B.; Enjalbal, C.; M'Kadmi, C.; Amblard, M.; Mehdi, A.; Martinez, J.; Subra, G. A New Way to Silicone-Based Peptide Polymers. Angewandte Chemie-International Edition 2015, 54 (12), 3778-3782.

(20) Martin, V.; Legrand, B.; Vezenkov, L. L.; Berthet, M.; Subra, G.; Calmes, M.; Bantignies, J.-L.; Martinez, J.; Amblard, M. Turning Peptide Sequences into Ribbon Foldamers by a Straightforward Multicyclization Reaction. Angewandte Chemie-International Edition 2015, 54 (47), 13966-13970.

(21) Vaillant, O.; El Cheikh, K.; Warther, D.; Brevet, D.; Maynadier, M.; Bouffard, E.; Salgues, F.; Jeanjean, A.; Puche, P.; Mazerolles, C., et al. Mannose-6-Phosphate Receptor: A Target for Theranostics of Prostate Cancer. Angewandte Chemie-International Edition 2015, 54 (20), 5952-5956.

(22) Munoz, J.; Garcia, C.; Joujoux, J. M.; Dandurand, M.; Meunier, L.; Stoebner, P. E. Metastatic cervical fasciitis revealing invasive lobular breast card noma. Annales De Dermatologie Et De Venereologie 2015, 142 (2), 112-114.

(23) Munoz, J.; Marque, M.; Dandurand, M.; Meunier, L.; Crow, Y. J.; Bessis, D. Type I interferonopathies. Annales De Dermatologie Et De Venereologie 2015, 142 (11), 653-663.

(24) Mueller, A.; Starobova, H.; Inserra, M. C.; Jin, A.-H.; Deuis, J. R.; Dutertre, S.; Lewis, R. J.; Alewood, P. F.; Daly, N. L.; Vetter, I. alpha-conotoxin MrIC is a biased agonist at alpha(7) nicotinic acetylcholine receptors. Biochemical Pharmacology 2015, 94 (2), 155-163.

(25) Razanamaro, O.; Rasoamanana, E.; Rakouth, B.; Randriamalala, J. R.; Rabakonadrianina, E.; Clement-Vidal, A.; Tsy, J.-M. L. P.; Menut, C.; Danthu, P. Chemical characterization of floral scents in the six endemic baobab species (Adansonia sp.) of Madagascar. Biochemical Systematics and Ecology 2015, 60, 238-248.

(26) Galano, J.-M.; Lee, J. C.-Y.; Gladine, C.; Comte, B.; Le Guennec, J.-Y.; Oger, C.; Durand, T. Non-enzymatic cyclic oxygenated metabolites of adrenic, docosahexaenoic, eicosapentaenoic and alpha-linolenic acids; bioactivities and potential use as biomarkers. Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids 2015, 1851 (4), 446-455.

(27) Serricchio, M.; Schmid, A. W.; Steinmann, M. E.; Sigel, E.; Rauch, M.; Julkowska, D.; Bonnefoy, S.; Fort, C.; Bastin, P.; Buetikofer, P. Flagellar membranes are rich in raft-forming phospholipids. Biology Open 2015, 4 (9), 1143-1153.

(28) Chamieh, J.; Biron, J. P.; Cipelletti, L.; Cottet, H. Monitoring Biopolymer Degradation by Taylor Dispersion Analysis. Biomacromolecules 2015, 16 (12), 3945-3951.

(29) Coumes, F.; Huang, C.-Y.; Huang, C.-H.; Coudane, J.; Domurado, D.; Li, S.; Darcos, V.; Huang, M.-H. Design and Development of Immunomodulatory Antigen Delivery Systems Based on Peptide/PEG-PLA Conjugate for Tuning Immunity. Biomacromolecules 2015, 16 (11), 3666-3673.

(30) Leroy, A.; Nottelet, B.; Bony, C.; Pinese, C.; Charlot, B.; Garric, X.; Noel, D.; Coudane, J. PLA-poloxamer/poloxamine copolymers for ligament tissue engineering: sound macromolecular design for degradable scaffolds and MSC differentiation. Biomaterials Science 2015, 3 (4), 617-626.

(31) Dabboue, H.; Builles, N.; Frouin, E.; Scott, D.; Ramos, J.; Marti-Mestres, G. Assessing the Impact of Mechanical Damage on Full-Thickness Porcine and Human Skin Using an In Vitro Approach. Biomed Research International 2015.

(32) Sasso, E.; Vitale, M.; Monteleone, F.; Boffo, F. L.; Santoriello, M.; Sarnataro, D.; Garbi, C.; Sabatella, M.; Crifo, B.; Paolella, L. A., et al. Binding of Carbonic Anhydrase IX to 45S rDNA Genes Is Prevented by Exportin-1 in Hypoxic Cells. Biomed Research International 2015.

(33) Biscans, A.; Rouanet, S.; Bertrand, J.-R.; Vasseur, J.-J.; Dupouy, C.; Debart, F. Synthesis, binding, nuclease resistance and cellular uptake properties of 2 '-O-acetalester-modified oligonucleotides containing cationic groups. Bioorganic & Medicinal Chemistry 2015, 23 (17), 5360-5368.

(34) Blayo, A.-L.; Maingot, M.; Aicher, B.; M'Kadmi, C.; Schmidt, P.; Mueller, G.; Teifel, M.; Guenther, E.; Gagne, D.; Denoyelle, S., et al. New trisubstituted 1,2,4-triazoles as ghrelin receptor antagonists. Bioorganic & Medicinal Chemistry Letters 2015, 25 (1), 20-24.

(35) Floquet, N.; Costa, M. G. S.; Batista, P. R.; Renault, P.; Bisch, P. M.; Raussin, F.; Martinez, J.; Morris, M. C.; Perahia, D. Conformational Equilibrium of CDK/Cyclin Complexes by Molecular Dynamics with Excited Normal Modes. Biophysical Journal 2015, 109 (6), 1179-1189.

(36) Solyom, Z.; Ma, P.; Schwarten, M.; Bosco, M.; Polidori, A.; Durand, G.; Willbold, D.; Brutscher, B. The Disordered Region of the HCV Protein NS5A: Conformational Dynamics, SH3 Binding, and Phosphorylation. Biophysical Journal 2015, 109 (7), 1483-1496.

(37) Salah, K. B. H.; Legrand, B.; Das, S.; Martinez, J.; Inguimbert, N. Straightforward Strategy to Substitute Amide Bonds by 1,2,3-Triazoles in Peptaibols Analogs Using Aib psi Tz -Xaa Dipeptides. Biopolymers 2015, 104 (5), 611-621.

(38) Peyressatre, M.; Prevel, C.; Pellerano, M.; Morris, M. C. Targeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitors. Cancers 2015, 7 (1), 179-237.

(39) Junthip, J.; Tabary, N.; Leclercq, L.; Martel, B. Cationic beta-cyclodextrin polymer applied to a dual cyclodextrin polyelectrolyte multilayer system. Carbohydrate Polymers 2015, 126, 156-167.

(40) Denis, R. G. P.; Joly-Amado, A.; Webber, E.; Langlet, F.; Schaeffer, M.; Padilla, S. L.; Cansell, C.; Dehouck, B.; Castel, J.; Delbes, A.-S., et al. Palatability Can Drive Feeding Independent of AgRP Neurons. Cell Metabolism 2015, 22 (4), 646-657.

(41) Dupin, L.; Zuttion, F.; Gehin, T.; Meyer, A.; Phaner-Goutorbe, M.; Vasseur, J.-J.; Souteyrand, E.; Morvan, F.; Chevolot, Y. Effects of the Surface Densities of Glycoclusters on the Determination of Their IC50 and K-d Value Determination by Using a Microarray. Chembiochem 2015, 16 (16), 2329-2336.

(42) Hamdi, A.; Lesnard, A.; Suzanne, P.; Robert, T.; Miteva, M. A.; Pellerano, M.; Didier, B.; Ficko-Blean, E.; Lobstein, A.; Hibert, M., et al. Tampering with Cell Division by Using Small-Molecule Inhibitors of CDK-CKS Protein Interactions. Chembiochem 2015, 16 (3), 432-439.

(43) Grychowska, K.; Masurier, N.; Verdie, P.; Satala, G.; Bojarski, A. J.; Martinez, J.; Pawlowski, M.; Subra, G.; Zajdel, P. Solid-Supported Synthesis and 5-HT7/5-HT1A Receptor Affinity of Arylpiperazinylbutyl Derivatives of 4,5-dihydro-1,2,4-triazine-6-(1H)-one. Chemical Biology & Drug Design 2015, 86 (4), 697-703.

(44) Benedetti, E.; Duchemin, N.; Bethge, L.; Vonhoff, S.; Klussmann, S.; Vasseur, J.-J.; Cossy, J.; Smietana, M.; Arseniyadis, S. DNA-cellulose: an economical, fully recyclable and highly effective chiral biomaterial for asymmetric catalysis. Chemical Communications 2015, 51 (28), 6076-6079.

(45) Croissant, J. G.; Mauriello-Jimenez, C.; Maynadier, M.; Cattoen, X.; Man, M. W. C.; Raehm, L.; Mongin, O.; Blanchard-Desce, M.; Garcia, M.; Gary-Bobo, M., et al. Synthesis of disulfide-based biodegradable bridged silsesquioxane nanoparticles for two-photon imaging and therapy of cancer cells. Chemical Communications 2015, 51 (61), 12324-12327.

(46) Cuyamendous, C.; Leung, K. S.; Durand, T.; Lee, J. C. Y.; Oger, C.; Galano, J. M. Synthesis and discovery of phytofurans: metabolites of alpha-linolenic acid peroxidation. Chemical Communications 2015, 51 (86), 15696-15699.

(47) Di Fiore, A.; Vergara, A.; Caterino, M.; Alterio, V.; Monti, S. M.; Ombouma, J.; Dumy, P.; Vullo, D.; Supuran, C. T.; Winum, J.-Y., et al. Hydroxylamine-O-sulfonamide is a versatile lead compound for the development of carbonic anhydrase inhibitors. Chemical Communications 2015, 51 (57), 11519-11522.

(48) Francoia, J.-P.; Pascal, R.; Vial, L. Monitoring clinical levels of heparin in human blood samples with an indicator-displacement assay. Chemical Communications 2015, 51 (10), 1953-1956.

(49) Francoia, J.-P.; Vial, L. A KISS (keep it simple, sensor) array for glycosaminoglycans. Chemical Communications 2015, 51 (99), 17544-17547.

(50) Pascal, R.; Pross, A. Stability and its manifestation in the chemical and biological worlds. Chemical Communications 2015, 51 (90), 16160-16165.

(51) Barbeyron, R.; Vasseur, J.-J.; Smietana, M. pH-controlled DNA- and RNA-templated assembly of short oligomers. Chemical Science 2015, 6 (1), 542-547.

(52) Clavel, C.; Waeles, P.; Fournel-Marotte, K.; Coutrot, F. Synthesis of triazolium-based mono- and tris-branched 1 rotaxanes using a molecular transporter of dibenzo-24-crown-8. Chemical Science 2015, 6 (8), 4828-4836.

(53) Lebouvier, N.; Lesaffre, L.; Hnawia, E.; Goue, C.; Menut, C.; Nour, M. Chemical Diversity of Podocarpaceae in New Caledonia: Essential Oils from Leaves of Dacrydium, Falcatifolium, and Acmopyle Species. Chemistry & Biodiversity 2015, 12 (12), 1848-1861.

(54) Beillard, A.; Golliard, E.; Gillet, V.; Bantreil, X.; Metro, T.-X.; Martinez, J.; Lamaty, F. Expedient Mechanosynthesis of N, N-Dialkyl Imidazoliums and Silver(I)-Carbene Complexes in a Ball-Mill. Chemistry-a European Journal 2015, 21 (49), 17614-17617.

(55) Berthet, M.; Davanier, F.; Dujardin, G.; Martinez, J.; Parrot, I. MgI2-Mediated Chemoselective Cleavage of Protecting Groups: An Alternative to Conventional Deprotection Methodologies. Chemistry-a European Journal 2015, 21 (31), 11014-11016.

(56) Bilyachenko, A. N.; Dronova, M. S.; Yalymov, A. I.; Lamaty, F.; Bantreil, X.; Martinez, J.; Bizet, C.; Shul'pina, L. S.; Korlyukov, A. A.; Arkhipov, D. E., et al. Cage-like Copper(II) Silsesquioxanes: Transmetalation Reactions and Structural, Quantum Chemical, and Catalytic Studies. Chemistry-a European Journal 2015, 21 (24), 8758-8770.

(57) de la Torre, A.; Lee, Y. Y.; Mazzoni, A.; Guy, A.; Bultel-Ponce, V.; Durand, T.; Oger, C.; Lee, J. C.-Y.; Galano, J.-M. Total Syntheses and In Vivo Quantitation of Novel Neurofuran and Dihomo-isofuran Derived from Docosahexaenoic Acid and Adrenic Acid. Chemistry-a European Journal 2015, 21 (6), 2442-2446.

(58) Metro, T.-X.; Bonnamour, J.; Reidon, T.; Duprez, A.; Sarpoulet, J.; Martinez, J.; Lamaty, F. Comprehensive Study of the Organic-Solvent-Free CDI-Mediated Acylation of Various Nucleophiles by Mechanochemistry. Chemistry-a European Journal 2015, 21 (36), 12787-12796.

(59) Touisni, N.; Kanfar, N.; Ulrich, S.; Dumy, P.; Supuran, C. T.; Mehdi, A.; Winum, J.-Y. Fluorescent Silica Nanoparticles with Multivalent Inhibitory Effects towards Carbonic Anhydrases. Chemistry-a European Journal 2015, 21 (29), 10306-10309.

(60) Coutrot, F. A Focus on Triazolium as a Multipurpose Molecular Station for pH-Sensitive Interlocked Crown-Ether-Based Molecular Machines. Chemistryopen 2015, 4 (5), 556-576.

(61) Estalayo-Adrian, S.; Lartia, R.; Meyer, A.; Vasseur, J.-J.; Morvan, F.; Defrancq, E. Assessment of the Full Compatibility of Copper(I)-Catalyzed Alkyne-Azide Cycloaddition and Oxime Click Reactions for bis-Labelling of Oligonucleotides. Chemistryopen 2015, 4 (2), 169-173.

(62) Brun, J.-F.; Varlet-Marie, E.; Fedou, C.; de Mauverger, E. R. Are metabolically healthy obese patients also hemorheologically healthy? Clinical Hemorheology and Microcirculation 2015, 61 (1), 39-46.

(63) Varlet-Marie, E.; de Mauverger, E. R.; Brun, J.-F. Are overall adiposity and abdominal adiposity separate or redundant determinants of blood viscosity? Clinical Hemorheology and Microcirculation 2015, 61 (1), 31-38.

(64) Bouffard, E.; El Cheikh, K.; Gallud, A.; Da Silva, A.; Maynadier, M.; Basile, I.; Gary-Bobo, M.; Morere, A.; Garcia, M. Why Anticancer Nanomedicine Needs Sugars? Current Medicinal Chemistry 2015, 22 (26), 3014-3024.

(65) Cortelazzo, A.; De Felice, C.; Guerranti, R.; Leoncini, R.; Barducci, A.; Leoncini, S.; Signorini, C.; Zollo, G.; Pecorelli, A.; Gagliardi, A., et al. Erythrocyte Cytoskeletal-plasma Membrane Protein Network in Rett Syndrome: Effects of omega-3 Polyunsaturated Fatty Acids. Current Proteomics 2015, 12 (4), 217-226.

(66) Durand, E.; Bayrasy, C.; Laguerre, M.; Barouh, N.; Lecomte, J.; Durand, T.; Balas, L.; Wrutniak-Cabello, C.; Cabello, G.; Villeneuve, P. Regioselective synthesis of diacylglycerol rosmarinates and evaluation of their antioxidant activity in fibroblasts. European Journal of Lipid Science and Technology 2015, 117 (8), 1159-1170.

(67) Arama, D. P.; Soualmia, F.; Lisowski, V.; Longevial, J.-F.; Bosc, E.; Maillard, L. T.; Martinez, J.; Masurier, N.; El Amri, C. Pyrido-imidazodiazepinones as a new class of reversible inhibitors of human kallikrein 7. European Journal of Medicinal Chemistry 2015, 93, 202-213.

(68) Cavalier, M.; Crouzin, N.; Ben Sedrine, A.; Ferreira, M. C. d. J.; Guiramand, J.; Cohen-Solal, C.; Fehrentz, J.-A.; Martinez, J.; Barbanel, G.; Vignes, M. Involvement of PKA and ERK pathways in ghrelin-induced long-lasting potentiation of excitatory synaptic transmission in the CA1 area of rat hippocampus. European Journal of Neuroscience 2015, 42 (8), 2568-2576.

(69) Bantreil, X.; Navals, P.; Martinez, J.; Lamaty, F. Iron/Caffeine as a Catalytic System for Microwave-Promoted Benzamide Formation. European Journal of Organic Chemistry 2015, (2), 417-422.

(70) Denoyelle, S.; Tambutet, G.; Masurier, N.; Maillard, L. T.; Martinez, J.; Lisowski, V. Synthesis of Thieno 3,2-e 1,4 diazepin-2-ones: Application of an Uncatalysed Pictet-Spengler Reaction. European Journal of Organic Chemistry 2015, (32), 7146-7153.

(71) Mathieu, L.; Bonnel, C.; Masurier, N.; Maillard, L. T.; Martinez, J.; Lisowski, V. Cross-Claisen Condensation of N-Fmoc-Amino Acids - A Short Route to Heterocyclic gamma-Amino Acids. European Journal of Organic Chemistry 2015, (10), 2262-2270.

(72) Meyer, A.; Noel, M.; Vasseur, J.-J.; Morvan, F. Hetero-Click Conjugation of Oligonucleotides with Glycosides Using Bifunctional Phosphoramidites. European Journal of Organic Chemistry 2015, (13), 2921-2927.

(73) Thillier, Y.; Sallamand, C.; Baraguey, C.; Vasseur, J.-J.; Debart, F. Solid-Phase Synthesis of Oligonucleotide 5 '-(alpha-P-Thio)triphosphates and 5 '-(alpha-P-Thio)(beta,gamma-methylene)triphosphates. European Journal of Organic Chemistry 2015, (2), 302-308.

(74) Nottelet, B.; Darcos, V.; Coudane, J. Aliphatic polyesters for medical imaging and theranostic applications. European Journal of Pharmaceutics and Biopharmaceutics 2015, 97, 350-370.

(75) Vert, M. After soft tissues, bone, drug delivery and packaging, PLA aims at blood. European Polymer Journal 2015, 68, 516-525.

(76) Supuran, C. T.; Winum, J.-Y. Designing carbonic anhydrase inhibitors for the treatment of breast cancer. Expert Opinion on Drug Discovery 2015, 10 (6), 591-597.

(77) Collado-Gonzalez, J.; Medina, S.; Durand, T.; Guy, A.; Galano, J.-M.; Torrecillas, A.; Ferreres, F.; Gil-Izquierdo, A. New UHPLC-QqQ-MS/MS method for quantitative and qualitative determination of free phytoprostanes in foodstuffs of commercial olive and sunflower oils. Food Chemistry 2015, 178, 212-220.

(78) Kadri, N.; Khettal, B.; Aid, Y.; Kherfellah, S.; Sobhi, W.; Barragan-Montero, V. Some physicochemical characteristics of pinus (Pinus halepensis Mill., Pinus pinea L., Pinus pinaster and Pinus canariensis) seeds from North Algeria, their lipid profiles and volatile contents. Food Chemistry 2015, 188, 184-192.

(79) Medina, S.; De Miguel-Elizaga, I.; Oger, C.; Galano, J.-M.; Durand, T.; Martinez-Villanueva, M.; Gil-Del Castillo, M. L.; Villegas-Martinez, I.; Ferreres, F.; Martinez-Hernandez, P., et al. Dihomo-isoprostanes-nonenzymatic metabolites of AdA-are higher in epileptic patients compared to healthy individuals by a new ultrahigh pressure liquid chromatography-triple quadrupole-tandem mass spectrometry method. Free Radical Biology and Medicine 2015, 79, 154-163.

(80) Roy, J.; Oger, C.; Thireau, J.; Roussel, J.; Mercier-Touzet, O.; Faure, D.; Pinot, E.; Farah, C.; Taber, D. F.; Cristol, J.-P., et al. Nonenzymatic lipid mediators, neuroprostanes, exert the antiarrhythmic properties of docosahexaenoic acid. Free Radical Biology and Medicine 2015, 86, 269-278.

(81) Galano, J. M.; Lee, Y. Y.; Durand, T.; Lee, J. C. Y. Special Issue on "Analytical Methods for Oxidized Biomolecules and Antioxidants" The use of isoprostanoids as biomarkers of oxidative damage, and their role in human dietary intervention studies. Free Radical Research 2015, 49 (5), 583-598.

(82) Lee, Y. Y.; Wong, C. K. C.; Oger, C.; Durand, T.; Galano, J. M.; Lee, J. C. Y. Prenatal exposure to the contaminant perfluorooctane sulfonate elevates lipid peroxidation during mouse fetal development but not in the pregnant dam. Free Radical Research 2015, 49 (8), 1015-1025.

(83) Leung, K. S.; Galano, J. M.; Durand, T.; Lee, J. C. Y. Current development in non-enzymatic lipid peroxidation products, isoprostanoids and isofuranoids, in novel biological samples. Free Radical Research 2015, 49 (7), 816-826.

(84) Guy, A.; Flanagan, S.; Durand, T.; Oger, C.; Galano, J.-M. Facile synthesis of cyclopentenone B-1- and L-1-type phytoprostanes. Frontiers in Chemistry 2015, 3.

(85) Tilmaciu, C.-M.; Morris, M. C. Carbon nanotube biosensors. Frontiers in Chemistry 2015, 3. (86) Attaoua, C.; Vincent, L.-A.; Jaoued, A. A.; Hadj-Kaddour, K.; Bai, Q.; De Vos, J.; Vian, L.; Cuq, P.

Differential involvement of glutathione S-transferase mu 1 and multidrug resistance protein 1 in melanoma acquired resistance to vinca alkaloids. Fundamental & Clinical Pharmacology 2015, 29 (1), 62-71.

(87) Vincent, L.-A.; Attaoua, C.; Bellis, M.; Rozkydalova, L.; Hadj-Kaddour, K.; Vian, L.; Cuq, P. Lysosomes and unfolded protein response, determinants of differential resistance of melanoma cells to vinca alkaloids. Fundamental & Clinical Pharmacology 2015, 29 (2), 164-177.

(88) Sizun, G.; Pierra, C.; Peyronnet, J.; Badaroux, E.; Rabeson, C.; Benzaria-Prad, S.; Surleraux, D.; Loi, A. G.; Musiu, C.; Liuzzi, M., et al. Design, synthesis and antiviral evaluation of 2 '-C-methyl branched guanosine pronucleotides: the discovery of IDX184, a potent liver-targeted HCV polymerase inhibitor. Future Medicinal Chemistry 2015, 7 (13), 1675-1700.

(89) Supuran, C. T.; Winum, J.-Y. Carbonic anhydrase IX inhibitors in cancer therapy: an update. Future Medicinal Chemistry 2015, 7 (11), 1407-1414.

(90) Metro, T.-X.; Salom-Roig, X. J.; Reverte, M.; Martinez, J.; Lamaty, F. Faster and cleaner dynamic kinetic resolution via mechanochemistry. Green Chemistry 2015, 17 (1), 204-208.

(91) Gu, B. J.; Field, J.; Dutertre, S.; Ou, A.; Kilpatrick, T. J.; Lechner-Scott, J.; Scott, R.; Lea, R.; Taylor, B. V.; Stankovich, J., et al. A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis. Human Molecular Genetics 2015, 24 (19), 5644-5654.

(92) Cens, T.; Rousset, M.; Collet, C.; Charreton, M.; Garnery, L.; Le Conte, Y.; Chahine, M.; Sandoz, J.-C.; Charnet, P. Molecular characterization and functional expression of the Apis mellifera voltage-dependent Ca2+ channels. Insect Biochemistry and Molecular Biology 2015, 58, 12-27.

(93) Vignes, M.; Novais, A. R. B.; Crouzin, N.; Cavalier, M.; Boubal, M.; Guiramand, J.; Cohen-Solal, C.; Ferreira, M. C. d. J.; Cambonie, G.; Barbanel, G. Restoring GABA tone rescues hippocampal long-term depression impaired after maternal immune stress. International Journal of Developmental Neuroscience 2015, 47, 36-37.

(94) Paolantoni, D.; Cantel, S.; Dumy, P.; Ulrich, S. A Dynamic Combinatorial Approach for Identifying Side Groups that Stabilize DNA-Templated Supramolecular Self-Assemblies. International Journal of Molecular Sciences 2015, 16 (2), 3609-3625.

(95) Chamieh, J.; Davanier, F.; Jannin, V.; Demarne, F.; Cottet, H. Size characterization of commercial micelles and microemulsions by Taylor dispersion analysis. International Journal of Pharmaceutics 2015, 492 (1-2), 46-54.

(96) Hu, Y.; Darcos, V.; Monge, S.; Li, S. Thermo-responsive drug release from self-assembled micelles of brush-like PLA/PEG analogues block copolymers. International Journal of Pharmaceutics 2015, 491 (1-2), 152-161.

(97) Jelonek, K.; Li, S.; Wu, X.; Kasperczyk, J.; Marcinkowski, A. Self-assembled filomicelles prepared from polylactide/poly(ethylene glycol) block copolymers for anticancer drug delivery. International Journal of Pharmaceutics 2015, 485 (1-2), 357-364.

(98) Pascal, R. Kinetic Barriers and the Self-organization of Life. Israel Journal of Chemistry 2015, 55 (8), 865-874.

(99) Warembourg, S.; Huberlant, S.; Garric, X.; Leprince, S.; de Tayrac, R.; Letouzey, V. Prevention and treatment of intra-uterine synechiae: Review of the literature. Journal De Gynecologie Obstetrique Et Biologie De La Reproduction 2015, 44 (4), 366-379.

(100) Barbosa, M.; Collado-Gonzalez, J.; Andrade, P. B.; Ferreres, F.; Valentao, P.; Galano, J.-M.; Durand, T.; Gil-Izquierdo, A. Nonenzymatic alpha-Linolenic Acid Derivatives from the Sea: Macroalgae as Novel Sources of Phytoprostanes. Journal of Agricultural and Food Chemistry 2015, 63 (28), 6466-6474.

(101) Collado-Gonzalez, J.; Perez-Lopez, D.; Memmi, H.; Carmen Gijon, M.; Medina, S.; Durand, T.; Guy, A.; Galano, J.-M.; Ferreres, F.; Torrecillas, A., et al. Water Deficit during Pit Hardening Enhances Phytoprostanes Content, a Plant Biomarker of Oxidative Stress, in Extra Virgin Olive Oil. Journal of Agricultural and Food Chemistry 2015, 63 (14), 3784-3792.

(102) Marhuenda, J.; Medina, S.; Diaz-Castro, A.; Martinez-Hernandez, P.; Arina, S.; Zafrilla, P.; Mulero, J.; Oger, C.; Galano, J.-M.; Durand, T., et al. Dependency of Phytoprostane Fingerprints of Must and Wine on Viticulture and Enological Processes. Journal of Agricultural and Food Chemistry 2015, 63 (41), 9022-9028.

(103) Liang, X.; Samways, D. S. K.; Wolf, K.; Bowles, E. A.; Richards, J. P.; Bruno, J.; Dutertre, S.; DiPaolo, R. J.; Egan, T. M. Quantifying Ca2+ Current and Permeability in ATP-gated P2X7 Receptors. Journal of Biological Chemistry 2015, 290 (12), 7930-7942.

(104) M'Kadmi, C.; Leyris, J.-P.; Onfroy, L.; Gales, C.; Sauliere, A.; Gagne, D.; Damian, M.; Mary, S.; Maingot, M.; Denoyelle, S., et al. Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling. Journal of Biological Chemistry 2015, 290 (45), 27021-27039.

(105) Bekri, S.; Leclercq, L.; Cottet, H. Polyelectrolyte multilayer coatings for the separation of proteins by capillary electrophoresis: Influence of polyelectrolyte nature and multilayer crosslinking. Journal of Chromatography A 2015, 1399, 80-87.

(106) Coussot, G.; Ladner, Y.; Bayart, C.; Faye, C.; Vigier, V.; Perrin, C. On-line capillary electrophoresis-based enzymatic methodology for the study of polymer-drug conjugates. Journal of Chromatography A 2015, 1376, 159-166.

(107) Oukacine, F.; Morel, A.; Desvignes, I.; Cottet, H. Size-based characterization of nanoparticle mixtures by the inline coupling of capillary electrophoresis to Taylor dispersion analysis. Journal of Chromatography A 2015, 1426, 220-225.

(108) Abla, M.; Unger, S.; Keller, S.; Bonnete, F.; Ebel, C.; Pucci, B.; Breyton, C.; Durand, G. Micellar and biochemical properties of a propyl-ended fluorinated surfactant designed for membrane-protein study. Journal of Colloid and Interface Science 2015, 445, 127-136.

(109) Mouri, A.; Diat, O.; El Ghzaoui, A.; Ly, I.; Dorandeu, C.; Maurel, J. C.; Devoisselle, J.-M.; Legrand, P. Development of pharmaceutical clear gel based on Peceol (R), lecithin, ethanol and water: Physicochemical characterization and stability study. Journal of Colloid and Interface Science 2015, 457, 152-161.

(110) Kadam, Y.; Pochat-Bohatier, C.; Sanchez, J.; El Ghzaoui, A. Modulating Viscoelastic Properties of Physically Cross linked Self-Assembled Gelatin Hydrogels through Optimized Solvent Conditions. Journal of Dispersion Science and Technology 2015, 36 (9), 1349-1356.

(111) Emilie, D.; Mallent, M.; Menut, C.; Chandre, F.; Martin, T. Behavioral Response of Bemisia tabaci (Hemiptera: Aleyrodidae) to 20 Plant Extracts. Journal of Economic Entomology 2015, 108 (4), 1890-1901.

(112) Ombouma, J.; Vullo, D.; Koehler, S.; Dumy, P.; Supuran, C. T.; Winum, J.-Y. N-glycosyl-N-hydroxysulfamides as potent inhibitors of Brucella suis carbonic anhydrases. Journal of Enzyme Inhibition and Medicinal Chemistry 2015, 30 (6), 1010-1012.

(113) Riafrecha, L. E.; Vullo, D.; Ouahrani-Bettache, S.; Koehler, S.; Dumy, P.; Winum, J.-Y.; Supuran, C. T.; Colinas, P. A. Inhibition of beta-carbonic anhydrases from Brucella suis with C-cinnamoyl glycosides incorporating the phenol moiety. Journal of Enzyme Inhibition and Medicinal Chemistry 2015, 30 (6), 1017-1020.

(114) Winum, J.-Y.; Supuran, C. T. Recent advances in the discovery of zinc-binding motifs for the development of carbonic anhydrase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 2015, 30 (2), 321-324.

(115) Soro, L. C.; Munier, S.; Atchibri, A. L. O.-A.; Grosmaire, L.; Menut, C.; Malan, K. A.; Pelissier, Y. Chemical Composition of Leaf Essential Oils of Lippia multiflora Mold. Grown in Savannah and Forest Area in the Ivory Coast. Journal of Essential Oil Bearing Plants 2015, 18 (1), 154-160.

(116) Roy, J.; Oliveira, L. T.; Oger, C.; Galano, J.-M.; Bultel-Ponce, V.; Richard, S.; Guimaraes, A. G.; Carneiro Vilela, J. M.; Andrade, M. S.; Durand, T., et al. Polymeric nanocapsules prevent oxidation of core-loaded molecules: evidence based on the effects of docosahexaenoic acid and neuroprostane on breast cancer cells proliferation. Journal of Experimental & Clinical Cancer Research 2015, 34.

(117) Garcin, G.; Guiraud, I.; Lacroix, M.; Genthon, C.; Rialle, S.; Joujoux, J.-M.; Meunier, L.; Lavabre-Bertrand, T.; Stoebner, P.-E.; Le Gallic, L. AMPK/HuR-Driven IL-20 Post-Transcriptional Regulation in Psoriatic Skin. Journal of Investigative Dermatology 2015, 135 (11), 2732-2741.

(118) Vieille, P.; Huberlant, S.; Bastide, S.; Bayon, Y.; de Tayrac, R. Evaluation of In Vivo Properties of Velosorb (TM) Fast Versus Vicryl (TM) Rapide in a Functional Rabbit Model of Intradermic Suture and Episiotomy. Journal of Investigative Surgery 2015, 28 (2), 109-114.

(119) Astafyeva, K.; Somaglino, L.; Desgranges, S.; Berti, R.; Patinote, C.; Langevin, D.; Lazeyras, F.; Salomir, R.; Polidori, A.; Contino-Pepin, C., et al. Perfluorocarbon nanodroplets stabilized by fluorinated surfactants: characterization and potentiality as theranostic agents. Journal of Materials Chemistry B 2015, 3 (14), 2892-2907.

(120) Croissant, J. G.; Mongin, O.; Hugues, V.; Blanchard-Desce, M.; Cattoen, X.; Man, M. W. C.; Stojanovic, V.; Charnay, C.; Maynadier, M.; Gary-Bobo, M., et al. Influence of the synthetic method on the properties of two-photon-sensitive mesoporous silica nanoparticles. Journal of Materials Chemistry B 2015, 3 (26), 5182-5188.

(121) Croissant, J. G.; Qi, C.; Mongin, O.; Hugues, V.; Blanchard-Desce, M.; Raehm, L.; Cattoen, X.; Man, M. W. C.; Maynadier, M.; Gary-Bobo, M., et al. Disulfide-gated mesoporous silica nanoparticles designed for two-photon-triggered drug release and imaging. Journal of Materials Chemistry B 2015, 3 (31), 6456-6461.

(122) Mauriello-Jimenez, C.; Croissant, J.; Maynadier, M.; Cattoen, X.; Man, M. W. C.; Vergnaud, J.; Chaleix, V.; Sol, V.; Garcia, M.; Gary-Bobo, M., et al. Porphyrin-functionalized mesoporous organosilica nanoparticles for two-photon imaging of cancer cells and drug delivery. Journal of Materials Chemistry B 2015, 3 (18), 3681-3684.

(123) Carta, F.; Osman, S. M.; Vullo, D.; Gullotto, A.; Winum, J.-Y.; AlOthman, Z.; Masini, E.; Supuran, C. T. Poly(amidoamine) Dendrimers with Carbonic Anhydrase Inhibitory Activity and Antiglaucoma Action. Journal of Medicinal Chemistry 2015, 58 (9), 4039-4045.

(124) Fanelli, R.; Besserer-Offroy, E.; Rene, A.; Cote, J.; Tetreault, P.; Collerette-Tremblay, J.; Longpre, J.-M.; Leduc, R.; Martinez, J.; Sarret, P., et al. Synthesis and Characterization in Vitro and in Vivo of (L)-(Trimethylsilyl)alanine Containing Neurotensin Analogues. Journal of Medicinal Chemistry 2015, 58 (19), 7785-7795.

(125) Marton, Z.; Guillon, R.; Krimm, I.; Preeti; Rahimova, R.; Egron, D.; Jordheim, L. P.; Aghajari, N.; Dumontet, C.; Perigaud, C., et al. Identification of Noncompetitive Inhibitors of Cytosolic 5 '-Nucleotidase II Using a Fragment-Based Approach. Journal of Medicinal Chemistry 2015, 58 (24), 9680-9696.

(126) Dalm, S. U.; Martens, J. W. M.; Sieuwerts, A. M.; van Deurzen, C. H. M.; Koelewijn, S. J.; de Blois, E.; Maina, T.; Nock, B. A.; Brunel, L.; Fehrentz, J.-A., et al. In Vitro and In Vivo Application of Radiolabeled Gastrin-Releasing Peptide Receptor Ligands in Breast Cancer. Journal of Nuclear Medicine 2015, 56 (5), 752-757.

(127) Jebors, S.; Pinese, C.; Nottelet, B.; Parra, K.; Amblard, M.; Mehdi, A.; Martinez, J.; Subra, G. Turning peptides in comb silicone polymers. Journal of Peptide Science 2015, 21 (3), 243-247.

(128) Shukla, M.; Htoo, H. H.; Wintachai, P.; Hernandez, J.-F.; Dubois, C.; Postina, R.; Xu, H.; Checler, F.; Smith, D. R.; Govitrapong, P., et al. Melatonin stimulates the nonamyloidogenic processing of beta APP through the positive transcriptional regulation of ADAM10 and ADAM17. Journal of Pineal Research 2015, 58 (2), 151-165.

(129) Himaya, S. W. A.; Jin, A.-H.; Dutertre, S.; Giacomotto, J.; Mohialdeen, H.; Vetter, I.; Alewood, P. F.; Lewis, R. J. Comparative Venomics Reveals the Complex Prey Capture Strategy of the Piscivorous Cone Snail Conus catus. Journal of Proteome Research 2015, 14 (10), 4372-4381.

(130) Li, C.; Guillen, J.; Rabah, N.; Blanjoie, A.; Debart, F.; Vasseur, J.-J.; Canard, B.; Decroly, E.; Coutard, B. mRNA Capping by Venezuelan Equine Encephalitis Virus nsP1: Functional Characterization and Implications for Antiviral Research. Journal of Virology 2015, 89 (16), 8292-8303.

(131) Ramakrishnan, S. K.; Jebors, S.; Martin, M.; Cloitre, T.; Agarwal, V.; Mehdi, A.; Martinez, J.; Subra, G.; Gergely, C. Engineered Adhesion Peptides for Improved Silicon Adsorption. Langmuir 2015, 31 (43), 11868-11874.

(132) Collado-Gonzalez, J.; Moriana, A.; Giron, I. F.; Corell, M.; Medina, S.; Durand, T.; Guy, A.; Galano, J.-M.; Valero, E.; Garrigues, T., et al. The phytoprostane content in green table olives is influenced by Spanish-style processing and regulated deficit irrigation. Lwt-Food Science and Technology 2015, 64 (2), 997-1003.

(133) Rossi, J.-C.; Maret, B.; Vidot, K.; Francoia, J.-P.; Cangiotti, M.; Lucchi, S.; Coppola, C.; Ottaviani, M. F. Multi-Technique Characterization of Poly-L-lysine Dendrigrafts-Cu(II) Complexes for Biocatalysis. Macromolecular Bioscience 2015, 15 (2), 275-290.

(134) Maret, B.; Crepet, A.; Faye, C.; Garrelly, L.; Ladaviere, C. Molar-Mass Analysis of Dendrigraft Poly(L-lysine) (DGL) Polyelectrolytes by SEC-MALLS: The "Cornerstone" Refractive Index Increment. Macromolecular Chemistry and Physics 2015, 216 (1), 95-105.

(135) Guerre, M.; Campagne, B.; Gimello, O.; Parra, K.; Ameduri, B.; Ladmiral, V. Deeper Insight into the MADIX Polymerization of Vinylidene Fluoride. Macromolecules 2015, 48 (21), 7810-7822.

(136) Leclercq, L.; Reinhard, S.; Chamieh, J.; Doeblinger, M.; Wagner, E.; Cottet, H. Fast Characterization of Polyplexes by Taylor Dispersion Analysis. Macromolecules 2015, 48 (19), 7216-7221.

(137) Chung, M. L. S.; Galano, J.-M.; Oger, C.; Durand, T.; Lee, J. C.-Y. Hyperoxia Elevates Adrenic Acid Peroxidation in Marine Fish and Is Associated with Reproductive Pheromone Mediators. Marine Drugs 2015, 13 (4), 2215-2232.

(138) Basile, M. A.; d'Ayala, G. G.; Malinconico, M.; Laurienzo, P.; Coudane, J.; Nottelet, B.; Della Ragione, F.; Oliva, A. Functionalized PCL/HA nanocomposites as microporous membranes for bone regeneration. Materials Science & Engineering C-Materials for Biological Applications 2015, 48, 457-468.

(139) Bantreil, X.; Cazin, C. S. J. Phosphite ligands in Ru-based olefin metathesis catalysts. Monatshefte Fur Chemie 2015, 146 (7), 1043-1052.

(140) Noureddine, A.; Lichon, L.; Maynadier, M.; Garcia, M.; Gary-Bobo, M.; Zink, J. I.; Cattoen, X.; Man, M. W. C. Controlled multiple functionalization of mesoporous silica nanoparticles: homogeneous implementation of pairs of functionalities communicating through energy or proton transfers. Nanoscale 2015, 7 (26), 11444-11452.

(141) Perrier, M.; Gallud, A.; Ayadi, A.; Kennouche, S.; Porredon, C.; Gary-Bobo, M.; Larionova, J.; Goze-Bac, C.; Zanca, M.; Garcia, M., et al. Investigation of cyano-bridged coordination nanoparticles Gd3+/ Fe(CN)(6) (3-)/D-mannitol as T-1-weighted MRI contrast agents. Nanoscale 2015, 7 (28), 11899-11903.

(142) Paesen, G. C.; Collet, A.; Sallamand, C.; Debart, F.; Vasseur, J.-J.; Canard, B.; Decroly, E.; Grimes, J. M. X-ray structure and activities of an essential Mononegavirales L-protein domain. Nature Communications 2015, 6.

(143) Rousset, M.; Cens, T.; Menard, C.; Bowerman, M.; Bellis, M.; Bruses, J.; Raoul, C.; Scamps, F.; Charnet, P. Regulation of neuronal high-voltage activated Ca(v)2 Ca2+ channels by the small GTPase RhoA. Neuropharmacology 2015, 97, 201-209.

(144) Zelli, R.; Longevial, J.-F.; Dumy, P.; Marra, A. Synthesis and biological properties of multivalent iminosugars. New Journal of Chemistry 2015, 39 (7), 5050-5074.

(145) Priet, S.; Lartigue, A.; Debart, F.; Claverie, J.-M.; Abergel, C. mRNA maturation in giant viruses: variation on a theme. Nucleic Acids Research 2015, 43 (7), 3776-3788.

(146) Jeanne, A.; Sick, E.; Devy, J.; Floquet, N.; Belloy, N.; Theret, L.; Boulagnon-Rombi, C.; Diebold, M.-D.; Dauchez, M.; Martiny, L., et al. Identification of TAX2 peptide as a new unpredicted anticancer agent. Oncotarget 2015, 6 (20), 17981-18000.

(147) Ward, C.; Meehan, J.; Mullen, P.; Supuran, C.; Dixon, J. M.; Thomas, J. S.; Winum, J.-Y.; Lambin, P.; Dubois, L.; Pavathaneni, N.-K., et al. Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models. Oncotarget 2015, 6 (28), 24856-24870.

(148) Bartolami, E.; Bessin, Y.; Bettache, N.; Gary-Bobo, M.; Garcia, M.; Dumy, P.; Ulrich, S. Multivalent DNA recognition by self-assembled clusters: deciphering structural effects by fragments screening and evaluation as siRNA vectors. Organic & Biomolecular Chemistry 2015, 13 (36), 9427-9438.

(149) Dondoni, A.; Marra, A. Validating the alkene and alkyne hydrophosphonylation as an entry to organophosphonates. Organic & Biomolecular Chemistry 2015, 13 (8), 2212-2215.

(150) Kanfar, N.; Bartolami, E.; Zelli, R.; Marra, A.; Winum, J.-Y.; Ulrich, S.; Dumy, P. Emerging trends in enzyme inhibition by multivalent nanoconstructs. Organic & Biomolecular Chemistry 2015, 13 (39), 9894-9906.

(151) Ligeour, C.; Dupin, L.; Angeli, A.; Vergoten, G.; Vidal, S.; Meyer, A.; Souteyrand, E.; Vasseur, J.-J.; Chevolot, Y.; Morvan, F. Importance of topology for glycocluster binding to Pseudomonas aeruginosa and Burkholderia ambifaria bacterial lectins. Organic & Biomolecular Chemistry 2015, 13 (46), 11244-11254.

(152) Ligeour, C.; Vidal, O.; Dupin, L.; Casoni, F.; Gillon, E.; Meyer, A.; Vidal, S.; Vergoten, G.; Lacroix, J.-M.; Souteyrand, E., et al. Mannose-centered aromatic galactoclusters inhibit the biofilm formation of Pseudomonas aeruginosa. Organic & Biomolecular Chemistry 2015, 13 (31), 8433-8444.

(153) Ovadia, R.; Lebrun, A.; Barvik, I.; Vasseur, J.-J.; Baraguey, C.; Alvarez, K. Synthesis and structural characterization of monomeric and dimeric peptide nucleic acids prepared by using microwave-promoted multicomponent reactions. Organic & Biomolecular Chemistry 2015, 13 (45), 11052-11071.

(154) Reverte, M.; Vasseur, J.-J.; Smietana, M. Nuclease stability of boron-modified nucleic acids: application to label-free mismatch detection. Organic & Biomolecular Chemistry 2015, 13 (43), 10604-10608.

(155) Fanelli, R.; Salah, K. B. H.; Inguimbert, N.; Didierjean, C.; Martinez, J.; Cavelier, F. Access to alpha,alpha-Disubstituted Disilylated Amino Acids and Their Use in Solid-Phase Peptide Synthesis. Organic Letters 2015, 17 (18), 4498-4501.

(156) Leoncini, S.; De Felice, C.; Signorini, C.; Zollo, G.; Cortelazzo, A.; Durand, T.; Galano, J.-M.; Guerranti, R.; Rossi, M.; Ciccoli, L., et al. Cytokine Dysregulation in MECP2- and CDKL5-Related Rett Syndrome: Relationships with Aberrant Redox Homeostasis, Inflammation, and omega-3 PUFAs. Oxidative Medicine and Cellular Longevity 2015.

(157) Deletre, E.; Chandre, F.; Williams, L.; Dumenil, C.; Menut, C.; Martin, T. Electrophysiological and behavioral characterization of bioactive compounds of the Thymus vulgaris, Cymbopogon winterianus, Cuminum cyminum and Cinnamomum zeylanicum essential oils against Anopheles gambiae and prospects for their use as bednet treatments. Parasites & Vectors 2015, 8.

(158) Huee, T.; Cauquil, L.; Fokou, J. B. H.; Dongmo, P. M. J.; Bakarnga-Via, I.; Menut, C. Acaricidal activity of five essential oils of Ocimum species on Rhipicephalus (Boophilus) microplus larvae. Parasitology Research 2015, 114 (1), 91-99.

(159) Verbeken, M.; Wynendaele, E.; Mauchauffee, E.; Bracke, N.; Stalmans, S.; Bojnik, E.; Benyhe, S.; Peremans, K.; Polis, I.; Burvenich, C., et al. Blood-brain transfer and antinociception of linear and cyclic N-methyl-guanidine and thiourea-enkephalins. Peptides 2015, 63, 10-21.

(160) Dall'Asta, M.; Bayle, M.; Neasta, J.; Scazzina, F.; Bruni, R.; Cros, G.; Del Rio, D.; Oiry, C. Protection of pancreatic beta-cell function by dietary polyphenols. Phytochemistry Reviews 2015, 14 (6), 933-959.

(161) Letouzey, V.; Huberlant, S.; Cornille, A.; Blanquer, S.; Guillaume, O.; Lemaire, L.; Garric, X.; de Tayrac, R. Tolerance and Long-Term MRI Imaging of Gadolinium-Modified Meshes Used in Soft Organ Repair. Plos One 2015, 10 (3).

(162) Park, J.-H.; Sevin, M.; Ramla, S.; Truffot, A.; Verrier, T.; Bouchot, D.; Courtois, M.; Bas, M.; Benali, S.; Bailly, F., et al. Calreticulin Mutations in Myeloproliferative Neoplasms: Comparison of Three Diagnostic Methods. Plos One 2015, 10 (10).

(163) Porsio, B.; Lemaire, L.; El Habnouni, S.; Darcos, V.; Franconi, F.; Garric, X.; Coudane, J.; Nottelet, B. MRI-visible nanoparticles from hydrophobic gadolinium poly(epsilon-caprolactone) conjugates. Polymer 2015, 56, 135-140.

(164) Al Samad, A.; Bakkour, Y.; Fanny, C.; El Omar, F.; Coudane, J.; Nottelet, B. From nanospheres to micelles: simple control of PCL-g-PEG copolymers' amphiphilicity through thiol-yne photografting. Polymer Chemistry 2015, 6 (28), 5093-5102.

(165) Su, F.; Shen, X.; Hu, Y.; Darcos, V.; Li, S. Biocompatibility of thermo-responsive PNIPAAm-PLLA-PNIPAAm triblock copolymer as potential drug carrier. Polymers for Advanced Technologies 2015, 26 (12), 1567-1574.

(166) Damian, M.; Mary, S.; Maingot, M.; M'Kadmi, C.; Gagne, D.; Leyris, J.-P.; Denoyelle, S.; Gaibelet, G.; Gavara, L.; Costa, M. G. d. S., et al. Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex. Proceedings of the National Academy of Sciences of the United States of America 2015, 112 (5), 1601-1606.

(167) Jin, A.-H.; Israel, M. R.; Inserra, M. C.; Smith, J. J.; Lewis, R. J.; Alewood, P. F.; Vetter, I.; Dutertre, S. delta-Conotoxin SuVIA suggests an evolutionary link between ancestral predator defence and the origin of fish-hunting behaviour in carnivorous cone snails. Proceedings of the Royal Society B-Biological Sciences 2015, 282 (1811).

(168) Jin, A.-H.; Vetter, I.; Himaya, S. W. A.; Alewood, P. F.; Lewis, R. J.; Dutertre, S. Transcriptome and proteome of Conus planorbis identify the nicotinic receptors as primary target for the defensive venom. Proteomics 2015, 15 (23-24), 4030-4040.

(169) Dubois, L. J.; Niemans, R.; van Kuijk, S. J. A.; Panth, K. M.; Parvathaneni, N.-K.; Peeters, S. G. J. A.; Zegers, C. M. L.; Rekers, N. H.; van Gisbergen, M. W.; Biemans, R., et al. New ways to image and target tumour hypoxia and its molecular responses. Radiotherapy and Oncology 2015, 116 (3), 352-357.

(170) Barbeyron, R.; Martin, A. R.; Vasseur, J.-J.; Smietana, M. DNA-templated borononucleic acid self assembly: a study of minimal complexity. Rsc Advances 2015, 5 (128), 105587-105591.

(171) Carrasco-Del Amor, A. M.; Collado-Gonzalez, J.; Aguayo, E.; Guy, A.; Galano, J. M.; Durand, T.; Gil-Izquierdo, A. Phytoprostanes in almonds: identification, quantification, and impact of cultivar and type of cultivation. Rsc Advances 2015, 5 (63), 51233-51241.

(172) Gallud, A.; Warther, D.; Maynadier, M.; Sefta, M.; Poyer, F.; Thomas, C. D.; Rouxel, C.; Mongin, O.; Blanchard-Desce, M.; Morere, A., et al. Identification of MRC2 and CD209 receptors as targets for photodynamic therapy of retinoblastoma using mesoporous silica nanoparticles. Rsc Advances 2015, 5 (92), 75167-75172.

(173) Sacco, M.; Charnay, C.; De Angelis, F.; Radoiu, M.; Lamaty, F.; Martinez, J.; Colacino, E. Microwave-ultrasound simultaneous irradiation: a hybrid technology applied to ring closing metathesis. Rsc Advances 2015, 5 (22), 16878-16885.

(174) Samuel, R.; Girard, E.; Chagnon, G.; Dejean, S.; Favier, D.; Coudane, J.; Nottelet, B. Radiopaque poly(epsilon-caprolactone) as additive for X-ray imaging of temporary implantable medical devices. Rsc Advances 2015, 5 (102), 84125-84133.

(175) Theron, C.; Gallud, A.; Giret, S.; Maynadier, M.; Gregoire, D.; Puche, P.; Jacquet, E.; Pop, G.; Sgarbura, O.; Bellet, V., et al. pH-operated hybrid silica nanoparticles with multiple H-bond stoppers for colon cancer therapy. Rsc Advances 2015, 5 (80), 64932-64936.

(176) Croissant, J.; Maynadier, M.; Mongin, O.; Hugues, V.; Blanchard-Desce, M.; Chaix, A.; Cattoen, X.; Man, M. W. C.; Gallud, A.; Gary-Bobo, M., et al. Enhanced Two-Photon Fluorescence Imaging and Therapy of Cancer Cells via Gold@Bridged Silsesquioxane Nanoparticles. Small 2015, 11 (3), 295-299.

(177) Marquick, A. L.; Montero, J.-L.; Lebrun, A.; Barragan-Montero, V. Straightforward synthesis towards mono and bis-phosphonic acid functionalised beta-cyclodextrins. Tetrahedron 2015, 71 (10), 1616-1621.

(178) Bartolami, E.; Gilles, A.; Dumy, P.; Ulrich, S. Synthesis of alpha-PNA containing a functionalized triazine as nucleobase analogue. Tetrahedron Letters 2015, 56 (18), 2319-2323.

(179) Dayde, B.; Pierra, C.; Gosselin, G.; Surleraux, D.; Da Costa, D.; Ilagouma, A. T.; Van der Lee, A.; Volle, J.-N.; Virieux, D.; Pirat, J.-L. Synthesis of unnatural 2- and 3-deoxyfuranose analogues (vol 55, pg 3706, 2014). Tetrahedron Letters 2015, 56 (15), 2034-2034.

(180) Dayde, B.; Pierra, C.; Gosselin, G.; Surleraux, D.; Da Costa, D.; Ilagouma, A. T.; Volle, J.-N.; Virieux, D.; Pirat, J.-L. Synthesis of unnatural 3 '-phospha-2 '-deoxyfuranose nucleoside analogues (vol 55, pg 6328, 2014). Tetrahedron Letters 2015, 56 (15), 2035-2035.

(181) Staderini, S.; Dondoni, A.; Marra, A. Metal-free synthesis of E-vinylphosphonates via photoinduced alkyne hydrophosphonylation and thiol promoted isomerization sequence. Tetrahedron Letters 2015, 56 (2), 374-377.

Janv – Oct 2016

(1) Amirbekyan, K.; Duchemin, N.; Benedetti, E.; Joseph, R.; Colon, A.; Markarian, S. A.; Bethge, L.; Vonhoff, S.; Klussmann, S.; Cossy, J., et al. Design, Synthesis, and Binding Affinity Evaluation of Hoechst 33258 Derivatives for the Development of Sequence-Specific DNA-Based Asymmetric Catalysts. Acs Catalysis 2016, 6 (5), 3096-3105.

(2) Grychowska, K.; Satala, G.; Kos, T.; Partyka, A.; Colacino, E.; Chaumont-Dubel, S.; Bantreil, X.; Wesolowska, A.; Pawlowski, M.; Martinez, J., et al. Novel 1H-Pyrrolo 3,2-c quinoline Based 5-HT6 Receptor Antagonists with Potential Application for the Treatment of Cognitive Disorders Associated with Alzheimer's Disease. Acs Chemical Neuroscience 2016, 7 (7), 972-983.

(3) Richichi, B.; Comito, G.; Renaudet, O.; Fiore, M.; Marra, A.; Stecca, B.; Pasquato, L.; Chiarugi, P.; Nativi, C. Role of a Preorganized Scaffold Presenting Four Residues of a GM-3 Lactone Mimetic on Melanoma Progression. Acs Medicinal Chemistry Letters 2016, 7 (1), 28-33.

(4) Reverte, M.; Vaissiere, A.; Boisguerin, P.; Vasseur, J.-J.; Smietana, M. RNase H-Assisted Imaging of Peroxynitrite in Living Cells with 5 '-Boronic Acid Modified DNA. Acs Sensors 2016, 1 (8), 970-974.

(5) Bednarova, E.; Colacino, E.; Lamaty, F.; Kotora, M. A Ruthenium Complex-Catalyzed Cyclotrimerization of Halodiynes with Nitriles. Synthesis of 2-and 3-Halopyridines. Advanced Synthesis & Catalysis 2016, 358 (12), 1916-1923.

(6) Manaargadoo-Catin, M.; Ali-Cherif, A.; Pougnas, J.-L.; Perrin, C. Hemolysis by surfactants - A review. Advances in Colloid and Interface Science 2016, 228, 1-16.

(7) Dupuy, A.; Le Faouder, P.; Vigor, C.; Oger, C.; Galano, J.-M.; Dray, C.; Lee, J. C.-Y.; Valet, P.; Gladine, C.; Durand, T., et al. Simultaneous quantitative profiling of 20 isoprostanoids from omega-3 and omega-6 polyunsaturated fatty acids by LC-MS/MS in various biological samples. Analytica Chimica Acta 2016, 921, 46-58.

(8) Leitner, M.; Stock, L. G.; Traxler, L.; Leclercq, L.; Bonazza, K.; Friedbacher, G.; Cottet, H.; Stutz, H.; Ebner, A. Mapping molecular adhesion sites inside SMIL coated capillaries using atomic force microscopy recognition imaging. Analytica Chimica Acta 2016, 930, 39-48.

(9) Roger, V.; Cottet, H.; Cipelletti, L. A New Robust Estimator of Polydispersity from Dynamic Light Scattering Data. Analytical Chemistry 2016, 88 (5), 2630-2636.

(10) Thevarajah, J. J.; Sutton, A. T.; Maniego, A. R.; Whitty, E. G.; Harrisson, S.; Cottet, H.; Castignolles, P.; Gaborieau, M. Quantifying the Heterogeneity of Chemical Structures in Complex Charged Polymers through the Dispersity of Their Distributions of Electrophoretic Mobilities or of Compositions. Analytical Chemistry 2016, 88 (3), 1674-1681.

(11) Dauvilliers, Y.; Evangelista, E.; Lopez, R.; Barateau, L.; Jaussent, I.; Cens, T.; Rousset, M.; Charnet, P. Absence of gamma-Aminobutyric Acid-A Receptor Potentiation in Central Hypersomnolence Disorders. Annals of Neurology 2016, 80 (2), 259-268.

(12) Pascal, R. Physicochemical Requirements Inferred for Chemical Self-Organization Hardly Support an Emergence of Life in the Deep Oceans of Icy Moons. Astrobiology 2016, 16 (5), 328-334.

(13) De Felice, C.; Leoncini, S.; Signorini, C.; Cortelazzo, A.; Rovero, P.; Durand, T.; Ciccoli, L.; Papini, A. M.; Hayek, J. Rett syndrome: An autoimmune disease? Autoimmunity Reviews 2016, 15 (4), 411-416.

(14) Kleindienst, A.; Battault, S.; Belaidi, E.; Tanguy, S.; Rosselin, M.; Boulghobra, D.; Meyer, G.; Gayrard, S.; Walther, G.; Geny, B., et al. Exercise does not activate the beta(3) adrenergic receptor-eNOS pathway, but reduces inducible NOS expression to protect the heart of obese diabetic mice. Basic Research in Cardiology 2016, 111 (4).

(15) Tai Nguyen, V.; Hospital, A.; Lionne, C.; Jordheim, L. P.; Dumontet, C.; Perigaud, C.; Chaloin, L.; Peyrottes, S. Beta-hydroxyphosphonate ribonucleoside analogues derived from 4-substituted-1,2,3-triazoles as IMP/GMP mimics: synthesis and biological evaluation. Beilstein Journal of Organic Chemistry 2016, 12, 1476-1486.

(16) Headley, C. A.; DiSilvestro, D.; Bryant, K. E.; Hemann, C.; Chen, C.-A.; Das, A.; Ziouzenkova, O.; Durand, G.; Villamena, F. A. Nitrones reverse hyperglycemia-induced endothelial dysfunction in bovine aortic endothelial cells. Biochemical Pharmacology 2016, 104, 108-117.

(17) Logez, C.; Damian, M.; Legros, C.; Dupre, C.; Guery, M.; Mary, S.; Wagner, R.; M'Kadmi, C.; Nosjean, O.; Fould, B., et al. Detergent-free Isolation of Functional G Protein-Coupled Receptors into Nanometric Lipid Particles. Biochemistry 2016, 55 (1), 38-48.

(18) Crauste, C.; Rosell, M.; Durand, T.; Vercauteren, J. Omega-3 polyunsaturated lipophenols, how and why? Biochimie 2016, 120, 62-74.

(19) Roy, J.; Le Guennec, J.-Y.; Galano, J.-M.; Thireau, J.; Bultel-Ponce, V.; Demion, M.; Oger, C.; Lee, J. C.-Y.; Durand, T. Non-enzymatic cyclic oxygenated metabolites of omega-3 polyunsaturated fatty acid: Bioactive drugs? Biochimie 2016, 120, 56-61.

(20) Rosselin, M.; Meyer, G.; Guillet, P.; Cheviet, T.; Walther, G.; Meister, A.; Hadjipaylou-Litina, D.; Durand, G. Divalent Amino-Acid-Based Amphiphilic Antioxidants: Synthesis, Self-Assembling Properties, and Biological Evaluation. Bioconjugate Chemistry 2016, 27 (3), 772-781.

(21) Zghaib, Z.; Guichou, J.-F.; Vappiani, J.; Bec, N.; Hadj-Kaddour, K.; Vincent, L.-A.; Paniagua-Gayraud, S.; Larroque, C.; Moarbess, G.; Cuq, P., et al. New imidazoquinoxaline derivatives: Synthesis, biological evaluation on melanoma, effect on tubulin polymerization and structure-activity relationships. Bioorganic & Medicinal Chemistry 2016, 24 (11), 2433-2440.

(22) Maingot, M.; Blayo, A.-L.; Denoyelle, S.; M'Kadmi, C.; Damian, M.; Mary, S.; Gagne, D.; Sanchez, P.; Aicher, B.; Schmidt, P., et al. New ligands of the ghrelin receptor based on the 1,2,4-triazole scaffold by introduction of a second chiral center. Bioorganic & Medicinal Chemistry Letters 2016, 26 (10), 2408-2412.

(23) Prevel, C.; Pellerano, M.; Gonzalez-Vera, J. A.; Henri, P.; Meunier, L.; Vollaire, J.; Josserand, V.; Morris, M. C. Fluorescent peptide biosensor for monitoring CDK4/cyclin D kinase activity in melanoma cell extracts, mouse xenografts and skin biopsies. Biosensors & Bioelectronics 2016, 85, 371-380.

(24) Agnaniet, H.; Mbot, E. J.; Keita, O.; Fehrentz, J.-A.; Ankli, A.; Gallud, A.; Garcia, M.; Gary-Bobo, M.; Lebibi, J.; Cresteil, T., et al. Antidiabetic potential of two medicinal plants used in Gabonese folk medicine. Bmc Complementary and Alternative Medicine 2016, 16.

(25) Foe, F. M.-C. N.; Tchinang, T. F. K.; Nyegue, A. M.; Abdou, J.-P.; Yaya, A. J. G.; Tchinda, A. T.; Essame, J.-L. O.; Etoa, F.-X. Chemical composition, in vitro antioxidant and anti-inflammatory properties of essential oils of four dietary and medicinal plants from Cameroon. Bmc Complementary and Alternative Medicine 2016, 16.

(26) Neasta, J.; Valmalle, C.; Coyne, A.-C.; Carnazzi, E.; Subra, G.; Galleyrand, J.-C.; Gagne, D.; M'Kadmi, C.; Bernad, N.; Berge, G., et al. The novel nonapeptide acein targets angiotensin converting enzyme in the brain and induces dopamine release. British Journal of Pharmacology 2016, 173 (8), 1314-1328.

(27) Baranger, K.; Marchalant, Y.; Bonnet, A. E.; Crouzin, N.; Carrete, A.; Paumier, J.-M.; Py, N. A.; Bernard, A.; Bauer, C.; Charrat, E., et al. MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid pathology and cognitive decline in a transgenic mouse model of Alzheimer's disease. Cellular and Molecular Life Sciences 2016, 73 (1), 217-236.

(28) Grassin, A.; Jourdan, M.; Dumy, P.; Boturyn, D. Influence of Pre-organised Architecture on Cell Adhesion by Using Multivalent RGD Compounds. Chembiochem 2016, 17 (6), 515-520.

(29) Pellerano, M.; Naud-Martin, D.; Peyressatre, M.; Prevel, C.; Teulade-Fichou, M.-P.; Morris, M.; Mahuteau-Betzer, F. TP-2Rho Is a Sensitive Solvatochromic Red-Shifted Probe for Monitoring the Interactions between CDK4 and CyclinD. Chembiochem 2016, 17 (8), 737-744.

(30) Alterio, V.; Cadoni, R.; Esposito, D.; Vullo, D.; Di Fiore, A.; Monti, S. M.; Caporale, A.; Ruvo, M.; Sechi, M.; Dumy, P., et al. Benzoxaborole as a new chemotype for carbonic anhydrase inhibition. Chemical Communications 2016, 52 (80), 11983-11986.

(31) Bartolami, E.; Bouillon, C.; Dumy, P.; Ulrich, S. Bioactive clusters promoting cell penetration and nucleic acid complexation for drug and gene delivery applications: from designed to self-assembled and responsive systems. Chemical Communications 2016, 52 (23), 4257-4273.

(32) Duchemin, N.; Benedetti, E.; Bethge, L.; Vonhoff, S.; Klussmann, S.; Vasseur, J.-J.; Cossy, J.; Smietana, M.; Arseniyadis, S. Expanding biohybrid-mediated asymmetric catalysis into the realm of RNA. Chemical Communications 2016, 52 (55), 8604-8607.

(33) Gonzalez-Vera, J. A.; Fueyo-Gonzalez, F.; Alkorta, I.; Peyressatre, M.; Morris, M. C.; Herranz, R. Highly solvatochromic and tunable fluorophores based on a 4,5-quinolimide scaffold: novel CDK5 probes. Chemical Communications 2016, 52 (62), 9652-9655.

(34) Mouton, J.; Turmine, M.; Van den Berghe, H.; Coudane, J. A new water-soluble polycarbobetaine showing high selectivity toward copper. Chemical Engineering Journal 2016, 283, 1168-1175.

(35) Lee, Y. Y.; Crauste, C.; Wang, H.; Leung, H. H.; Vercauteren, J.; Galano, J.-M.; Oger, C.; Durand, T.; Wang, J. M.-F.; Lee, J. C.-Y. Extra Virgin Olive Oil Reduced Polyunsaturated Fatty Acid and Cholesterol Oxidation in Rodent Liver: Is This Accounted for Hydroxytyrosol-Fatty Acid Conjugation? Chemical Research in Toxicology 2016, 29 (10), 1689-1698.

(36) Remond, E.; Martin, C.; Martinez, J.; Cavelier, F. Silicon-Containing Amino Acids: Synthetic Aspects, Conformational Studies, and Applications to Bioactive Peptides. Chemical Reviews 2016, 116 (19), 11654-11684.

(37) Roy, B.; Depaix, A.; Perigaud, C.; Peyrottes, S. Recent Trends in Nucleotide Synthesis. Chemical Reviews 2016, 116 (14), 7854-7897.

(38) Murillo-Sanchez, S.; Beaufils, D.; Gonzalez Manas, J. M.; Pascal, R.; Ruiz-Mirazo, K. Fatty acids' double role in the prebiotic formation of a hydrophobic dipeptide. Chemical Science 2016, 7 (5), 3406-3413.

(39) Ciccione, J.; Jia, T.; Col, J.-L.; Parra, K.; Amblard, M.; Jebors, S.; Martinez, J.; Mehdi, A.; Subra, G. Unambiguous and Controlled One-Pot Synthesis of Multifunctional Silica Nanoparticles. Chemistry of Materials 2016, 28 (3), 885-889.

(40) Echalier, C.; Pinese, C.; Garric, X.; Van Den Berghe, H.; Bilak, E. J.; Martinez, J.; Mehdi, A.; Subra, G. Easy Synthesis of Tunable Hybrid Bioactive Hydrogels. Chemistry of Materials 2016, 28 (5), 1261-1265.

(41) Knuhtsen, A.; Legrand, B.; Van der Poorten, O.; Amblard, M.; Martinez, J.; Ballet, S.; Kristensen, J. L.; Pedersen, D. S. Conformationally Constrained Peptidomimetics as Inhibitors of the Protein Arginine Methyl Transferases. Chemistry-a European Journal 2016, 22 (39), 14022-14028.

(42) Legigan, T.; Riss-Yaw, B.; Clavel, C.; Coutrot, F. Active Esters as Pseudostoppers for Slippage Synthesis of 2 Pseudorotaxane Building Blocks: A Straightforward Route to Multi-Interlocked Molecular Machines. Chemistry-a European Journal 2016, 22 (26), 8835-8847.

(43) Legrand, B.; Andre, C.; Moulat, L.; Didierjean, C.; Hermet, P.; Bantignies, J.-L.; Martinez, J.; Amblard, M.; Calmes, M. 12/14/14-Helix Formation in 2:1 alpha/beta-Hybrid Peptides Containing Bicyclo 2.2.2 octane Ring Constraints. Chemistry-a European Journal 2016, 22 (34), 11986-11990.

(44) Liu, Z.; Rigger, L.; Rossi, J.-C.; Sutherland, J. D.; Pascal, R. Mixed Anhydride Intermediates in the Reaction of 5(4H)-Oxazolones with Phosphate Esters and Nucleotides. Chemistry-a European Journal 2016, 22 (42), 14940-14949.

(45) Noureddine, A.; Gary-Bobo, M.; Lichon, L.; Garcia, M.; Zink, J. I.; Man, M. W. C.; Cattoen, X. Bis-clickable Mesoporous Silica Nanoparticles: Straightforward Preparation of Light-Actuated Nanomachines for Controlled Drug Delivery with Active Targeting. Chemistry-a European Journal 2016, 22 (28), 9624-9630.

(46) Waeles, P.; Riss-Yaw, B.; Coutrot, F. Synthesis of a pH-Sensitive Hetero 4 Rotaxane Molecular Machine that Combines c2 Daisy and 2 Rotaxane Arrangements. Chemistry-a European Journal 2016, 22 (20), 6837-6845.

(47) Wang, S.; Dupin, L.; Noel, M.; Carroux, C. J.; Renaud, L.; Gehin, T.; Meyer, A.; Souteyrand, E.; Vasseur, J.-J.; Vergoten, G., et al. Toward the Rational Design of Galactosylated Glycoclusters That Target Pseudomonas aeruginosa Lectin A (LecA): Influence of Linker Arms That Lead to Low-Nanomolar Multivalent Ligands. Chemistry-a European Journal 2016, 22 (33), 11785-11794.

(48) Vezenkov, L. L.; Sanchez, C. A.; Bellet, V.; Martin, V.; Maynadier, M.; Bettache, N.; Lisowski, V.; Martinez, J.; Garcia, M.; Amblard, M., et al. Structure-Activity Relationships of JMV4463, a

Vectorized CathepsinD Inhibitor with Antiproliferative Properties: The Unique Role of the AMPA-Based Vector. Chemmedchem 2016, 11 (3), 302-308.

(49) Riss-Yaw, B.; Waeles, P.; Coutrot, F. Reverse Anomeric Effect in Large-Amplitude Pyridinium Amide-Containing Mannosyl 2 Rotaxane Molecular Shuttles. Chemphyschem 2016, 17 (12), 1860-1869.

(50) Hanquet, G.; Salom-Roig, X.; Lanners, S. New Insights into the Synthesis and Biological Activity of the Pamamycin Macrodiolides. Chimia 2016, 70 (1-2), 20-28.

(51) Brun, J.-F.; Varlet-Marie, E.; de Mauverger, E. R.; Fedou, C.; Pollatz, M. Hemorheologic effects of low intensity endurance training in type 2 diabetic patients: A pilot study. Clinical Hemorheology and Microcirculation 2016, 61 (4), 579-589.

(52) Varga, A.; Lionne, C.; Roy, B. Intracellular Metabolism of Nucleoside/Nucleotide Analogues: A Bottleneck to Reach Active Drugs on HIV Reverse Transcriptase. Current Drug Metabolism 2016, 17 (3), 237-252.

(53) Haeck, J. C.; Bol, K.; de Ridder, C. M. A.; Brunel, L.; Fehrentz, J. A.; Martinez, J.; van Weerden, W. M.; Bernsen, M. R.; de Jong, M.; Veenland, J. F. Imaging heterogeneity of peptide delivery and binding in solid tumors using SPECT imaging and MRI. Ejnmmi Research 2016, 6, 1-9.

(54) Rosselin, M.; Tuccio, B.; Perio, P.; Villamena, F. A.; Fabre, P.-L.; Durand, G. Electrochemical and Spin-Trapping Properties of para-substituted alpha-Phenyl-N-tert-butyl Nitrones. Electrochimica Acta 2016, 193, 231-239.

(55) Ladner, Y.; Coussot, G.; Ebner, S.; Ibrahim, A.; Vidal, L.; Perrin, C. Optimization of a nano-enzymatic reactor for on-line tryptic digestion of polypeptide conjugates by capillary electrophoresis. Electrophoresis 2016, 37 (2), 256-266.

(56) Moarbess, G.; Guichou, J.-F.; Paniagua-Gayraud, S.; Chouchou, A.; Marcadet, O.; Leroy, F.; Ruedas, R.; Cuq, P.; Deleuze-Masquefa, C.; Bonnet, P.-A. New IKK inhibitors: Synthesis of new imidazo 1,2-a quinoxaline derivatives using microwave assistance and biological evaluation as IKK inhibitors. European Journal of Medicinal Chemistry 2016, 115, 268-274.

(57) Point, V.; Benarouche, A.; Zarrillo, J.; Guy, A.; Magnez, R.; Fonseca, L.; Raux, B.; Leclaire, J.; Buono, G.; Fotiadu, F., et al. Slowing down fat digestion and absorption by an oxadiazolone inhibitor targeting selectively gastric lipolysis. European Journal of Medicinal Chemistry 2016, 123, 834-848.

(58) Hapau, D.; Remond, E.; Fanelli, R.; Vivancos, M.; Rene, A.; Cote, J.; Besserer-Offroy, E.; Longpre, J.-M.; Martinez, J.; Zaharia, V., et al. Stereoselective Synthesis of -(5-Arylthiazolyl) -Amino Acids and Use in Neurotensin Analogues. European Journal of Organic Chemistry 2016, (5), 1017-1024.

(59) Porte, V.; Thioloy, M.; Pigoux, T.; Metro, T.-X.; Martinez, J.; Lamaty, F. Peptide Mechanosynthesis by Direct Coupling of N-Protected -Amino Acids with Amino Esters. European Journal of Organic Chemistry 2016, (21), 3505-3508.

(60) Chavanieu, A.; Pugniere, M. Developments in SPR Fragment Screening. Expert Opinion on Drug Discovery 2016, 11 (5), 489-499.

(61) Delosiere, M.; Sante-Lhoutellier, V.; Chantelauze, C.; Durand, D.; Thomas, A.; Joly, C.; Pujos-Guillot, E.; Remond, D.; Comte, B.; Gladine, C., et al. Quantification of 4-hydroxy-2-nonenal-protein adducts in the in vivo gastric digesta of mini-pigs using a GC-MS/MS method with accuracy profile validation. Food & Function 2016, 7 (8), 3497-3504.

(62) Aksamija, A.; Polidori, A.; Plasson, R.; Dangles, O.; Tomao, V. The inclusion complex of rosmarinic acid into beta-cyclodextrin: A thermodynamic and structural analysis by NMR and capillary electrophoresis. Food Chemistry 2016, 208, 258-263.

(63) Maria Carrasco-Del Amor, A.; Aguayo, E.; Collado-Gonzalez, J.; Guy, A.; Galano, J.-M.; Durand, T.; Gil-Izquierdo, A. Impact of packaging atmosphere, storage and processing conditions on the generation of phytoprostanes as quality processing compounds in almond kernels. Food Chemistry 2016, 211, 869-875.

(64) Poonlaphdecha, J.; Gantet, P.; Maraval, I.; Sauvage, F.-X.; Menut, C.; Morere, A.; Boulanger, R.; Wuest, M.; Gunata, Z. Biosynthesis of 2-acetyl-1-pyrroline in rice calli cultures: Demonstration of 1-pyrroline as a limiting substrate. Food Chemistry 2016, 197, 965-971.

(65) Alejandra Garcia-Flores, L.; Medina, S.; Cejuela, R.; Miguel Martinez-Sanz, J.; Oger, C.; Galano, J.-M.; Durand, T.; Casas-Pina, T.; Martinez-Hernandez, P.; Ferreres, F., et al. Assessment of oxidative stress biomarkers - neuroprostanes and dihomo-isoprostanes - in the urine of elite triathletes after two weeks of moderate-altitude training. Free Radical Research 2016, 50 (5), 485-494.

(66) Nieves-Cordones, M.; Rodenas, R.; Chavanieu, A.; Rivero, R. M.; Martinez, V.; Gaillard, I.; Rubio, F. Uneven HAK/KUP/KT Protein Diversity Among Angiosperms: Species Distribution and Perspectives. Frontiers in Plant Science 2016, 7.

(67) Beaudoux, X.; Virot, M.; Chave, T.; Durand, G.; Leturcq, G.; Nikitenko, S. I. Vitamin C boosts ceria-based catalyst recycling. Green Chemistry 2016, 18 (12), 3656-3668.

(68) Mouri, A.; Legrand, P.; El Ghzaoui, A.; Dorandeu, C.; Maurel, J. C.; Devoisselle, J.-M. Formulation, physicochemical characterization and stability study of lithium-loaded microemulsion system. International Journal of Pharmaceutics 2016, 502 (1-2), 117-124.

(69) Mback, M. N. L. N.; Agnaniet, H.; Nguimatsia, F.; Dongmo, P. M. J.; Fokou, J. B. H.; Bakarnga-via, I.; Boyom, F. F.; Menut, C. Optimization of antifungal activity of Aeollanthus heliotropioides oliv essential oil and Time Kill Kinetic Assay. Journal De Mycologie Medicale 2016, 26 (3), 233-243.

(70) Junthip, J.; Tabary, N.; Chai, F.; Leclercq, L.; Maton, M.; Cazaux, F.; Neut, C.; Paccou, L.; Guinet, Y.; Staelens, J.-N., et al. Layer-by-layer coating of textile with two oppositely charged cyclodextrin polyelectrolytes for extended drug delivery. Journal of Biomedical Materials Research Part A 2016, 104 (6), 1408-1424.

(71) Cia, D.; Cubizolle, A.; Crauste, C.; Jacquemot, N.; Guillou, L.; Vigor, C.; Angebault, C.; Hamel, C. P.; Vercauteren, J.; Brabet, P. Phloroglucinol protects retinal pigment epithelium and photoreceptor against all-trans-retinal-induced toxicity and inhibits A2E formation. Journal of Cellular and Molecular Medicine 2016, 20 (9), 1651-1663.

(72) Francoia, J.-P.; Vial, L. ChemBrows: An Open-Source Application Software To Keep Up to Date with the Current Literature. Journal of Chemical Education 2016, 93 (6), 1137-1139.

(73) Bekri, S.; Leclercq, L.; Cottet, H. Influence of the ionic strength of acidic background electrolytes on the separation of proteins by capillary electrophoresis. Journal of Chromatography A 2016, 1432, 145-151.

(74) Roland, A.; Delpech, S.; Dagan, L.; Ducasse, M.-A.; Cavelier, F.; Schneider, R. Innovative analysis of 3-mercaptohexan-1-ol,3-mercaptohexylacetate and their corresponding disulfides in wine by stable isotope dilution assay and nano-liquid chromatography tandem mass spectrometry. Journal of Chromatography A 2016, 1468, 154-163.

(75) Gosselin-Badaroudine, P.; Moreau, A.; Simard, L.; Cens, T.; Rousset, M.; Collet, C.; Charnet, P.; Chahine, M. Biophysical characterization of the honeybee DSC1 orthologue reveals a novel voltage-dependent Ca2+ channel subfamily: Ca(V)4. Journal of General Physiology 2016, 148 (2), 133-145.

(76) Daguzan, C.; Moulin, M.; Kulyk-Barbier, H.; Davrinche, C.; Peyrottes, S.; Champagne, E. Aminobisphosphonates Synergize with Human Cytomegalovirus To Activate the Antiviral Activity of V gamma 9V delta 2 Cells. Journal of Immunology 2016, 196 (5), 2219-2229.

(77) Al Samad, A.; Bethry, A.; Koziolova, E.; Netopilik, M.; Etrych, T.; Bakkour, Y.; Coudane, J.; El Omar, F.; Nottelet, B. PCL-PEG graft copolymers with tunable amphiphilicity as efficient drug delivery systems. Journal of Materials Chemistry B 2016, 4 (37), 6228-6239.

(78) Croissant, J. G.; Picard, S.; Aggad, D.; Klausen, M.; Jimenez, C. M.; Maynadier, M.; Mongin, O.; Clermont, G.; Genin, E.; Cattoen, X., et al. Fluorescent periodic mesoporous organosilica nanoparticles dual-functionalized via click chemistry for two-photon photodynamic therapy in cells. Journal of Materials Chemistry B 2016, 4 (33), 5567-5574.

(79) Jimenez, C. M.; Knezevic, N. Z.; Rubio, Y. G.; Szunerits, S.; Boukherroub, R.; Teodorescu, F.; Croissant, J. G.; Hocine, O.; Seric, M.; Raehm, L., et al. Nanodiamond-PMO for two-photon PDT and drug delivery. Journal of Materials Chemistry B 2016, 4 (35), 5803-5808.

(80) Knezevic, N. Z.; Stojanovic, V.; Chaix, A.; Bouffard, E.; El Cheikh, K.; Morere, A.; Maynadier, M.; Lemercier, G.; Garcia, M.; Gary-Bobo, M., et al. Ruthenium(II) complex-photosensitized multifunctionalized porous silicon nanoparticles for two-photon near-infrared light responsive imaging and photodynamic cancer therapy. Journal of Materials Chemistry B 2016, 4 (7), 1337-1342.

(81) Yala, S.; Boustta, M.; Gallet, O.; Hindie, M.; Carreiras, F.; Benachour, H.; Sidane, D.; Khireddine, H. New synthesis method of HA/P(D,L)LA composites: study of fibronectin adsorption and their effects in osteoblastic behavior for bone tissue engineering. Journal of Materials Science-Materials in Medicine 2016, 27 (9).

(82) Boibessot, T.; Zschiedrich, C. P.; Lebeau, A.; Benimelis, D.; Dunyach-Remy, C.; Lavigne, J.-P.; Szurmant, H.; Benfodda, Z.; Meffre, P. The Rational Design, Synthesis, and Antimicrobial Properties of Thiophene Derivatives That Inhibit Bacterial Histidine Kinases. Journal of Medicinal Chemistry 2016, 59 (19), 8830-8847.

(83) Mercredi, P. Y.; Bucca, N.; Loeliger, B.; Gaines, C. R.; Mehta, M.; Bhargava, P.; Tedbury, P. R.; Charlier, L.; Floquet, N.; Muriaux, D., et al. Structural and Molecular Determinants of Membrane Binding by the HIV-1 Matrix Protein. Journal of Molecular Biology 2016, 428 (8), 1637-1655.

(84) Legrand, F.; Breyton, C.; Guillet, P.; Ebel, C.; Durand, G. Hybrid Fluorinated and Hydrogenated Double-Chain Surfactants for Handling Membrane Proteins. Journal of Organic Chemistry 2016, 81 (2), 681-688.

(85) Skowron, P.-T.; Dumartin, M.; Jeamet, E.; Perret, F.; Gourlaouen, C.; Baudouin, A.; Fenet, B.; Naubron, J.-V.; Fotiadu, F.; Vial, L., et al. On-Demand Cyclophanes: Substituent-Directed Self-Assembling, Folding, and Binding. Journal of Organic Chemistry 2016, 81 (2), 654-661.

(86) Kalistratova, A.; Legrand, B.; Verdie, P.; Naydenova, E.; Amblard, M.; Martinez, J.; Subra, G. A switchable stapled peptide. Journal of Peptide Science 2016, 22 (3), 143-148.

(87) Machinskaya, A. E.; Leclercq, L.; Boustta, M.; Vert, M.; Vasilevskaya, V. V. Salt Effects on Macrophase Separations in Non-Stoichiometric Mixtures of Oppositely Charged Macromolecules: Theory and Experiment. Journal of Polymer Science Part B-Polymer Physics 2016, 54 (17), 1717-1730.

(88) Jimenez, C. M.; Rubio, Y. G.; Saunier, V.; Warther, D.; Stojanovic, V.; Raehm, L.; Frochot, C.; Arnoux, P.; Garcia, M.; Morere, A., et al. 20-nm-sized mesoporous silica nanoparticles with porphyrin photosensitizers for in vitro photodynamic therapy. Journal of Sol-Gel Science and Technology 2016, 79 (3), 447-456.

(89) Casiraghi, M.; Damian, M.; Lescop, E.; Point, E.; Moncoq, K.; Morellet, N.; Leyy, D.; Marie, J.; Guittet, E.; Baneres, J.-L., et al. Functional Modulation of a G Protein-Coupled Receptor Conformational Landscape in a Lipid Bilayer. Journal of the American Chemical Society 2016, 138 (35), 11170-11175.

(90) Breche, Q.; Chagnon, G.; Machado, G.; Girard, E.; Nottelet, B.; Garric, X.; Favier, D. Mechanical behaviour's evolution of a PLA-b-PEG-b-PLA triblock copolymer during hydrolytic degradation. Journal of the Mechanical Behavior of Biomedical Materials 2016, 60, 288-300.

(91) Collado-Gonzalez, J.; Perez-Lopez, D.; Memmi, H.; Carmen Gijon, M.; Medina, S.; Durand, T.; Guy, A.; Galano, J.-M.; Jose Fernandez, D.; Carro, F., et al. Effect of the season on the free phytoprostane content in Cornicabra extra virgin olive oil from deficit-irrigated olive trees. Journal of the Science of Food and Agriculture 2016, 96 (5), 1585-1592.

(92) Brundu, S.; Palma, L.; Picceri, G. G.; Ligi, D.; Orlandi, C.; Galluzzi, L.; Chiarantini, L.; Casabianca, A.; Schiavano, G. F.; Santi, M., et al. Glutathione Depletion Is Linked with Th2 Polarization in Mice with a Retrovirus-Induced Immunodeficiency Syndrome, Murine AIDS: Role of Proglutathione Molecules as Immunotherapeutics. Journal of Virology 2016, 90 (16), 7118-7130.

(93) Lounis, F. M.; Chamieh, J.; Gonzalez, P.; Cottet, H.; Leclercq, L. Prediction of Polyelectrolyte Complex Stoichiometry for Highly Hydrophilic Polyelectrolytes. Macromolecules 2016, 49 (10), 3881-3888.

(94) Thangaraj, V.; Lepoitevin, M.; Smietana, M.; Balanzat, E.; Bechelany, M.; Janot, J.-M.; Vasseur, J.-J.; Subramanian, S.; Balme, S. Detection of short ssDNA and dsDNA by current-voltage measurements using conical nanopores coated with Al2O3 by atomic layer deposition. Microchimica Acta 2016, 183 (3), 1011-1017.

(95) Prashanth, J. R.; Dutertre, S.; Jin, A. H.; Lavergne, V.; Hamilton, B.; Cardoso, F. C.; Griffin, J.; Venter, D. J.; Alewood, P. F.; Lewis, R. J. The role of defensive ecological interactions in theevolution of conotoxins. Molecular Ecology 2016, 25 (2), 598-615.

(96) Sarlak, G.; Htoo, H. H.; Hernandez, J. F.; Iizasa, H.; Checler, F.; Konietzko, U.; Song, W.; Vincent, B. Sox2 FUNCTIONALLY INTERACTS WITH beta APP, THE beta APP INTRACELLULAR DOMAIN AND ADAM10 AT A TRANSCRIPTIONAL LEVEL IN HUMAN CELLS. Neuroscience 2016, 312, 153-164.

(97) Cortelazzo, A.; De Felice, C.; Guerranti, R.; Signorini, C.; Leoncini, S.; Pecorelli, A.; Scalabri, F.; Madonna, M.; Filosa, S.; Della Giovampaola, C., et al. Abnormal N-glycosylation pattern for brain nucleotide pyrophosphatase-5 (NPP-5) in Mecp2-mutant murine models of Rett syndrome. Neuroscience Research 2016, 105, 28-34.

(98) Alguacil, J.; Reyes, D.; Aubin, Y.; Roy, B.; Perigaud, C.; Champagne, E.; Peyrottes, S. Exploring synthetic pathways for nucleosidic derivatives of potent phosphoantigens. New Journal of Chemistry 2016, 40 (7), 6046-6052.

(99) Geant, P.-Y.; Mohamed, B. S.; Perigaud, C.; Peyrottes, S.; Uttaro, J.-P.; Mathe, C. Probing the reactivity of H-phosphonate derivatives for the hydrophosphonylation of various alkenes and alkynes under free-radical conditions. New Journal of Chemistry 2016, 40 (6), 5318-5324.

(100) Polidori, A.; Raynal, S.; Barret, L.-A.; Dahani, M.; Barrot-Ivolot, C.; Jungas, C.; Frotscher, E.; Keller, S.; Ebel, C.; Breyton, C., et al. Sparingly fluorinated maltoside-based surfactants for membrane-protein stabilization. New Journal of Chemistry 2016, 40 (6), 5364-5378.

(101) Hwang, C. S.; Xu, L.; Wang, W.; Ulrich, S.; Zhang, L.; Chong, J.; Shin, J. H.; Huang, X.; Kool, E. T.; McKenna, C. E., et al. Functional interplay between NTP leaving group and base pair recognition during RNA polymerase II nucleotide incorporation revealed by methylene substitution. Nucleic Acids Research 2016, 44 (8), 3820-3828.

(102) Bultel-Ponce, V.; Durand, T.; Guy, A.; Oger, C.; Galano, J.-M. Non enzymatic metabolites of polyunsaturated fatty acids: friend or foe. Ocl-Oilseeds and Fats Crops and Lipids 2016, 23 (1).

(103) Maynadier, M.; Basile, I.; Gallud, A.; Gary-Bobo, M.; Garcia, M. Combination treatment with proteasome inhibitors and antiestrogens has a synergistic effect mediated by p21(WAF1) in estrogen receptor-positive breast cancer. Oncology Reports 2016, 36 (2), 1127-1134.

(104) Balas, L.; Bertrand-Michel, J.; Viars, F.; Faugere, J.; Lefort, C.; Caspar-Bauguil, S.; Langin, D.; Durand, T. Regiocontrolled syntheses of FAHFAs and LC-MS/MS differentiation of regioisomers. Organic & Biomolecular Chemistry 2016, 14 (38), 9012-9020.

(105) Biscans, A.; Rouanet, S.; Vasseur, J.-J.; Dupouy, C.; Debart, F. A versatile post-synthetic method on a solid support for the synthesis of RNA containing reduction-responsive modifications. Organic & Biomolecular Chemistry 2016, 14 (29), 7010-7017.

(106) Bonnel, C.; Legrand, B.; Bantignies, J. L.; Petitjean, H.; Martinez, J.; Masurier, N.; Maillard, L. T. FT-IR and NMR structural markers for thiazole-based gamma-peptide foldamers. Organic & Biomolecular Chemistry 2016, 14 (37), 8664-8669.

(107) Cordeau, E.; Cantel, S.; Gagne, D.; Lebrun, A.; Martinez, J.; Subra, G.; Enjalbal, C. Selenazolidine: a selenium containing proline surrogate in peptide science. Organic & Biomolecular Chemistry 2016, 14 (34), 8101-8108.

(108) Di Fiore, A.; De Simone, G.; Alterio, V.; Riccio, V.; Winum, J.-Y.; Carta, F.; Supuran, C. T. The anticonvulsant sulfamide JNJ-26990990 and its S,S-dioxide analog strongly inhibit carbonic anhydrases: solution and X-ray crystallographic studies. Organic & Biomolecular Chemistry 2016, 14 (21), 4853-4858.

(109) Bantreil, X.; Bourderioux, A.; Mateo, P.; Hagerman, C. E.; Selkti, M.; Brachet, E.; Belmont, P. Phosphine-Triggered Selectivity Switch in Silver-Catalyzed o-Alkynylbenzohydroxamic Acid Cycloisomerizations. Organic Letters 2016, 18 (19), 4814-4817.

(110) Beaufils, D.; Jepaul, S.; Liu, Z.; Boiteau, L.; Pascal, R. The Activation of Free Dipeptides Promoted by Strong Activating Agents in Water Does not Yield Diketopiperazines. Origins of Life and Evolution of Biospheres 2016, 46 (1), 19-30.

(111) Pascal, R.; Pross, A. The Logic of Life. Origins of Life and Evolution of Biospheres 2016, 46 (4), 507-513.

(112) Deletre, E.; Chandre, F.; Barkman, B.; Menut, C.; Martin, T. Naturally occurring bioactive compounds from four repellent essential oils against Bemisia tabaci whiteflies. Pest Management Science 2016, 72 (1), 179-189.

(113) Cordeau, E.; Arnaudguilhem, C.; Bouyssiere, B.; Hagege, A.; Martinez, J.; Subra, G.; Cantel, S.; Enjalbal, C. Investigation of Elemental Mass Spectrometry in Pharmacology for Peptide Quantitation at Femtomolar Levels. Plos One 2016, 11 (6).

(114) Signorini, C.; De Felice, C.; Leoncini, S.; Moller, R. S.; Zollo, G.; Buoni, S.; Cortelazzo, A.; Guerranti, R.; Durand, T.; Ciccolil, L., et al. MECP2 Duplication Syndrome: Evidence of Enhanced Oxidative Stress. A Comparison with Rett Syndrome. Plos One 2016, 11 (3).

(115) Breche, Q.; Chagnon, G.; Machado, G.; Nottelet, B.; Garric, X.; Girard, E.; Favier, D. A non-linear viscoelastic model to describe the mechanical behavior's evolution of biodegradable polymers during hydrolytic degradation. Polymer Degradation and Stability 2016, 131, 145-156.

(116) Balas, L.; Durand, T. Dihydroxylated E,E,Z-docosatrienes. An overview of their synthesis and biological significance. Progress in Lipid Research 2016, 61, 1-18.

(117) Bilyachenko, A. N.; Levitsky, M. M.; Yalymov, A. I.; Korlyukov, A. A.; Vologzhanina, A. V.; Kozlov, Y. N.; Shul'pina, L. S.; Nesterov, D. S.; Pombeiro, A. J. L.; Lamaty, F., et al. A heterometallic (Fe6Na8) cage-like silsesquioxane: synthesis, structure, spin glass behavior and high catalytic activity. Rsc Advances 2016, 6 (53), 48165-48180.

(118) Coumes, F.; Beaute, L.; Domurado, D.; Li, S.; Lecommandoux, S.; Coudane, J.; Darcos, V. Self-assembly of well-defined triblock copolymers based on poly(lactic acid) and poly(oligo(ethylene glycol) methyl ether methacrylate) prepared by ATRP. Rsc Advances 2016, 6 (58), 53370-53377.

(119) Echalier, C.; Kalistratova, A.; Ciccione, J.; Lebrun, A.; Legrand, B.; Naydenova, E.; Gagne, D.; Fehrentz, J.-A.; Marie, J.; Amblard, M., et al. Selective homodimerization of unprotected peptides using hybrid hydroxydimethylsilane derivatives. Rsc Advances 2016, 6 (39), 32905-32914.

(120) Konnert, L.; Dimassi, M.; Gonnet, L.; Lamaty, F.; Martinez, J.; Colacino, E. Poly(ethylene) glycols and mechanochemistry for the preparation of bioactive 3,5-disubstituted hydantoins. Rsc Advances 2016, 6 (43), 36978-36986.

(121) Medina, S.; Carrasco-Torres, R.; Amor, I.; Oger, C.; Galano, J.-M.; Durand, T.; Villegas-Martinez, I.; Auvin, S.; Ferreres, F.; Gil-Izquierdo, A. Antiepileptic drugs affect lipid oxidative markers-neuroprostanes and F-2-dihomo-isoprostanes- in patients with epilepsy: differences among first-, second-, and third-generation drugs by UHPLC-QqQ-MS/MS. Rsc Advances 2016, 6 (86), 82969-82976.

(122) Nyalosaso, J. L.; Rascol, E.; Pisani, C.; Dorandeu, C.; Dumail, X.; Maynadier, M.; Gary-Bobo, M.; Him, J. L. K.; Bron, P.; Garcia, M., et al. Synthesis, decoration, and cellular effects of magnetic mesoporous silica nanoparticles. Rsc Advances 2016, 6 (62), S7275-S7283.

(123) Younis, M.; Darcos, V.; Paniagua, C.; Ronjat, P.; Lemaire, L.; Nottelet, B.; Garric, X.; Bakkour, Y.; El Nakat, J. H.; Coudane, J. MRI-visible polymer based on poly(methyl methacrylate) for imaging applications. Rsc Advances 2016, 6 (7), 5754-5760.

(124) Zelli, R.; Bartolami, E.; Longevial, J.-F.; Bessin, Y.; Dumy, P.; Marra, A.; Ulrich, S. A metal-free synthetic approach to peptide-based iminosugar clusters as novel multivalent glycosidase inhibitors. Rsc Advances 2016, 6 (3), 2210-2216.

(125) Burgy, O.; Wettstein, G.; Bellaye, P. S.; Decologne, N.; Racoeur, C.; Goirand, F.; Beltramo, G.; Hernandez, J.-F.; Kenani, A.; Camus, P., et al. Deglycosylated bleomycin has the antitumor activity of bleomycin without pulmonary toxicity. Science Translational Medicine 2016, 8 (326).

(126) de la Torre, A.; Oger, C.; Bultel-Ponce, V.; Durand, T.; Galano, J.-M. Benzoyl Shift: A New Approach to Reverse Regioselectivity in the Monoprotection of vic-Diols. Synlett 2016, 27 (15), 2205-2208.

(127) Fanelli, R.; Martinez, J.; Cavelier, F. Expedient Synthesis of Fmoc-(S)--Fluoroleucine and Late-Stage Fluorination of Peptides. Synlett 2016, 27 (9), 1403-1407.

(128) de la Torre, A.; Cuyamendous, C.; Bultel-Ponce, V.; Durand, T.; Galano, J.-M.; Oger, C. Recent advances in the synthesis of tetrahydrofurans and applications in total synthesis. Tetrahedron 2016, 72 (33), 5003-5025.

(129) Milbeo, P.; Maurent, K.; Moulat, L.; Lebrun, A.; Didierjean, C.; Aubert, E.; Martinez, J.; Calmes, M. N-Pyrrolidine-based alpha/beta-peptides incorporating ABOC, a constrained bicyclic beta-amino acid, for asymmetric aldol reaction catalysis. Tetrahedron 2016, 72 (13), 1706-1715.

(130) Masurier, N.; Lebrun, A.; Canitrot, D.; Chezal, J.-M.; Moreau, E. Synthesis under moderate pressure of 3-imidazo 1,2-alpha pyridinylidene pyrrol-2-ones. Tetrahedron Letters 2016, 57 (24), 2583-2586.

(131) Geant, P.-Y.; Grenet, E.; Martinez, J.; Salom-Roig, X. J. Stereoselective divergent synthesis of 1,2-aminoalcohol-containing heterocycles from a common chiral nonracemic building block. Tetrahedron-Asymmetry 2016, 27 (1), 22-30.

(132) Chatalic, K. L. S.; Konijnenberg, M.; Nonnekens, J.; de Blois, E.; Hoeben, S.; de Ridder, C.; Brunel, L.; Fehrentz, J.-A.; Martinez, J.; van Gent, D. C., et al. In Vivo Stabilization of a Gastrin-Releasing Peptide Receptor Antagonist Enhances PET Imaging and Radionuclide Therapy of Prostate Cancer in Preclinical Studies. Theranostics 2016, 6 (1), 104-117.