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List of References 1. Aihara M, Scardino P T, Truong L D, Wheeler T M, Goad . I R, Yang G, Thompson T C. The frequency of apoptosis correlates with the prognosis of Gleason grade 3 adenocarcinoma of the prostate. Cancer, 1995, 75: 522-529. 2. Aihara M, Truong L D, Dunn J K, Wheeler T M, Scardino P T, Thompson T C. Frequency of apoptotic bodies positively correlates mth Gleason Grade in prostate cancer. Human Pathology., 1994, 25: 797-801. 3 Alberts B, Bray D, Lewis J, Raff M, Roberts K and Watson JD. Molecular Biology of the cell. New York: Garland, 1983, 424-6. 4. Albor A, Kaku S and Kulesz-Martin M. Wild type and mutant forms of p53 activate human topoisomerase I. A possible mechanism for gain of function in mutants..Cancer Research 1998; 58, 2091-2094. 5. Alcalde RE, Terakado N, Otsuki K, and Matsumura T. Angiogenesis and expression of platelet derived epidermal cell growth factor in oral squamous cell carcinoma. Oncology. 54: 324-8, 1997. 6. Almog N. Rotter V Involvement of p53 in cell differentiation and development, Biochim. Biophys Acta 1333 (1997) F1-F27. 7. Anneroth G, Smith C. Platz H and Willen R. Correlation between histopathology and behavior. Johnson NW. Risk markers for oral diseases vol 2. oral cancer detection of patients and lesion at risk. Cambridge Univ ersity press, 1991, Cambridge UK ( 57-75)) 8. Aotake T, Lu CD, Chiba Y, Muraoka R, Tanigawa N Changes of angiogenesis and tumor cell apoptosis during colorectal carcinogenesis.. Clinical Cancer Research 1999 Jan;5(1):135-42 9. Ashkenazi and Dixit VM. Death receptors: Signalling and modulation. Science. 1998; 281: 1305-1308. 10.Awwad S, Jaros E, Somes J and Lunec J. (1996). p53 overexpression in head and neck carcinoma and radiotherapy results. International Journal of Radiation oncology biology and physics, 34. 323-332. 11.Bartkova J. Lukas J and Muller H. Abnormal patterns of D type cyclin expression and G1 regulation in head and neck cancer. Cancer Research 1995, 55, 949-956. 12.Baserga, R., Oncogenes and the strategy of growth factors. Cell. 1994, 79: 927-930.

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List of References

1. Aihara M, Scardino P T, Truong L D, Wheeler T M, Goad .I R, Yang G, Thompson T C. The frequency of apoptosis correlates with the prognosis of Gleason grade 3 adenocarcinoma of the prostate. Cancer, 1995, 75: 522-529.

2. Aihara M, Truong L D, Dunn J K, Wheeler T M, Scardino P T, Thompson T C. Frequency of apoptotic bodies positively correlates mth Gleason Grade in prostate cancer. Human Pathology., 1994, 25: 797-801.

3 Alberts B, Bray D, Lewis J, Raff M, Roberts K and Watson JD. Molecular Biology of the cell. New York: Garland, 1983, 424-6.

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7. Anneroth G, Smith C. Platz H and Willen R. Correlation between histopathology and behavior. Johnson NW. Risk markers for oral diseases vol 2. oral cancer detection of patients and lesion at risk. Cambridge Univ ersity press, 1991, Cambridge UK ( 57-75))

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RELEVANT PUB1,ICATIONS

1. D.Ravi, K.R.Nalinakumari, R.S.Rajaram, MKrishnan Nau, M.R.Pillai. 'Expression of Programmed cell death regulatory p53 and bcl-2 proteins in oral cancer'. Cancer Letters 105 (1996) 139.146.

2. M.R.Pillai, D.Ravi and M.K.Nair.' Chemoprevention of oral cancer: the need for effective biological monitoring'. Singapore Dental Journal 22 (1997). (Review)

3. D.Ravi, K.Ramdas, B.S.Mathew, K.R.Nalinakumari, M.K Nau, M.R. Pillai. 'De novo programmed cell death in oral cancer'. Histopathology 34 (1999) 241 -249.

4. D.Ravi, K.Ramdas, B.S.Mathew, K.R.Nal'mak~unari M.K.Nair and M.R.Pillai. 'Angiogenesis during tumor progression 111 the oral cavity is related to reduced apoptosis and high tumor cell proliferation'. Oral Oncology 34 (1998) 543-548.

5. MR.PiUai, K.Ramdas, K.R.Nalinakumari D.Ravi and M.K.Nair. 'Cellular manifestations of tumor progression in the oral mucosa: Role of human papillomavirus, apoptosis, angiogenesis, proliferation and tumor associated genes p53, bcl-2 and bax. Oral Oncology Vol VI Proceedings of the 6th International Congress on Oral Cancer. (1999) 51-54.

6. D.Ravi, K R Panikkar, K.Ramdas, M.K Nair and M.R. P~llai. Prognostic significance of p53 expression in oral cancer. Proceedings of 1 2 ~ Kerala Science congress, Jan-2000.

7. D.Ravi, K.R Panickkar, M.K. Nair and M.R. Pillai. ' Apoptosis: insights on future directions in cancer therapy' (Review)National Medical Journal of India. (2000), 13.71- 78.

8. D.Ravi, K.Ramdas, B.S.Mathew, K . R . N a l i i r i , K.R.Panikkar, M.K.Nair and M.R.PiUai. Mutant p53 Protein: Prognostic significance in oral cancer. (2000) (Communicated)

9. D.Ravi, K.Randas, B.S.Mathew, K.R.Nalinakumari, K.R.Panikkar, M.K.Nair and M.R.Pillai. Apoptosis, angiogenesis and proliferation: trifunctional roles in tumor response to radiotherapy for oral cancer. (2000) (Communicated)

10. D.Ravi, K.Ramdas, K.R.Pamkkar, M.K.Nair and M.R.Pillai 'Angiogenesis and apoptosis in the prediction of radiotherapy response in oral cancer' in 'Radiobiology - 2000' International conference on Radiobiology Feb 17-19, held at Trivandnun. (AR Gopal Ayenkar award for BEST POSTER presentation)