Light 1. Compare and contrast photopic and scotopic vision. 2. Why do we have both rods and cones?...

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Light Light 1. 1. Compare and contrast photopic and scotopic vision. Compare and contrast photopic and scotopic vision. 2. 2. Why do we have both rods and cones? (N) Why do we have both rods and cones? (N) 3. 3. Discuss the significance of convergence and divergence in the retinal processing of Discuss the significance of convergence and divergence in the retinal processing of rod and cone signals. (M) rod and cone signals. (M) 4. 4. Outline the visual processes that allow our vision to operate over a large Outline the visual processes that allow our vision to operate over a large luminance range. (N) luminance range. (N) 5. 5. How is the visual system able to function at widely varying levels of light intensity? How is the visual system able to function at widely varying levels of light intensity? (N,V) (N,V) 6. 6. In what ways can one quantify the performance of the eye? What factors limit its In what ways can one quantify the performance of the eye? What factors limit its performance? (M) performance? (M) 7. 7. What are believed to be the mechanisms of colour vision? How can defects in it be What are believed to be the mechanisms of colour vision? How can defects in it be explained? explained? 8. 8. How may visual acuity be tested? What factors influence it? (M) How may visual acuity be tested? What factors influence it? (M) 9. 9. Discuss factors affecting the quality of the optical image on the retina. To what Discuss factors affecting the quality of the optical image on the retina. To what extent does the quality limit visual acuity? extent does the quality limit visual acuity? 10. 10. How does the visual system cope with the conflicting demands of high absolute How does the visual system cope with the conflicting demands of high absolute sensitivity and high spatial acuity? (M) sensitivity and high spatial acuity? (M) 11. 11. What structural features of the retina help to explain visual acuity? (M) What structural features of the retina help to explain visual acuity? (M) 12. 12. What factors limit visual acuity at different light levels? What factors limit visual acuity at different light levels? 13. 13. What factors determine whether a visual stimulus will be seen? What factors determine whether a visual stimulus will be seen? 14. 14. Write a concise account of any two of the following: colour vision; visual acuity; Write a concise account of any two of the following: colour vision; visual acuity; dark adaptation; eye movements; pupillary reflexes. (V) dark adaptation; eye movements; pupillary reflexes. (V)

Transcript of Light 1. Compare and contrast photopic and scotopic vision. 2. Why do we have both rods and cones?...

Page 1: Light 1. Compare and contrast photopic and scotopic vision. 2. Why do we have both rods and cones? (N) 3. Discuss the significance of convergence and divergence.

LightLight1.1. Compare and contrast photopic and scotopic vision.Compare and contrast photopic and scotopic vision.2.2. Why do we have both rods and cones? (N)Why do we have both rods and cones? (N)3.3. Discuss the significance of convergence and divergence in the retinal Discuss the significance of convergence and divergence in the retinal

processing of rod and cone signals. (M)processing of rod and cone signals. (M)4.4. Outline the visual processes that allow our vision to operate over a large Outline the visual processes that allow our vision to operate over a large

luminance range. (N)luminance range. (N)5.5. How is the visual system able to function at widely varying levels of light How is the visual system able to function at widely varying levels of light

intensity? (N,V)intensity? (N,V)6.6. In what ways can one quantify the performance of the eye? What In what ways can one quantify the performance of the eye? What

factors limit its performance? (M)factors limit its performance? (M)7.7. What are believed to be the mechanisms of colour vision? How can What are believed to be the mechanisms of colour vision? How can

defects in it be explained?defects in it be explained?8.8. How may visual acuity be tested? What factors influence it? (M)How may visual acuity be tested? What factors influence it? (M)9.9. Discuss factors affecting the quality of the optical image on the retina. Discuss factors affecting the quality of the optical image on the retina.

To what extent does the quality limit visual acuity?To what extent does the quality limit visual acuity?10.10. How does the visual system cope with the conflicting demands of high How does the visual system cope with the conflicting demands of high

absolute sensitivity and high spatial acuity? (M)absolute sensitivity and high spatial acuity? (M)11.11. What structural features of the retina help to explain visual acuity? (M)What structural features of the retina help to explain visual acuity? (M)12.12. What factors limit visual acuity at different light levels?What factors limit visual acuity at different light levels?13.13. What factors determine whether a visual stimulus will be seen?What factors determine whether a visual stimulus will be seen?14.14. Write a concise account of any two of the following: colour vision; visual Write a concise account of any two of the following: colour vision; visual

acuity; dark adaptation; eye movements; pupillary reflexes. (V)acuity; dark adaptation; eye movements; pupillary reflexes. (V)

Page 2: Light 1. Compare and contrast photopic and scotopic vision. 2. Why do we have both rods and cones? (N) 3. Discuss the significance of convergence and divergence.

Outline the visual Outline the visual processes that allow our processes that allow our vision to operate over a vision to operate over a large luminance rangelarge luminance range

Pupillary reflexPupillary reflex Rods vs. ConesRods vs. Cones

Pooling (spatial)Pooling (spatial) Temporal summationTemporal summation

Automatic gain control (mediated by fall in Automatic gain control (mediated by fall in Calcium)Calcium) Increases cGMP synthesis (GCAP)Increases cGMP synthesis (GCAP) Closes cGMP activated channel (Calmodulin)Closes cGMP activated channel (Calmodulin) Increases recoverin binding to Rh*Increases recoverin binding to Rh*

Horizontal cells (synaptic inhibition)Horizontal cells (synaptic inhibition) Bleaching (fewer receptors available)Bleaching (fewer receptors available)

Page 3: Light 1. Compare and contrast photopic and scotopic vision. 2. Why do we have both rods and cones? (N) 3. Discuss the significance of convergence and divergence.

Lamb model of Lamb model of photoreceptorphotoreceptor

Page 4: Light 1. Compare and contrast photopic and scotopic vision. 2. Why do we have both rods and cones? (N) 3. Discuss the significance of convergence and divergence.

Compare and contrast Compare and contrast photopic and scotopic photopic and scotopic

visionvision Rods - just rhodopsinRods - just rhodopsin B&WB&W More in peripheriesMore in peripheries Convergence 1000:1Convergence 1000:1

Rod bipolar, AII, gcRod bipolar, AII, gc Sensitivity 10Sensitivity 10-4-4 cd/m cd/m22

Acuity lowAcuity low Slower, temporal Slower, temporal

summationsummation

Cones - 3 kinds of Cones - 3 kinds of opsinsopsins

ColourColour Fovea (and rim)Fovea (and rim) Convergence smallConvergence small

On/off bipolar, gcOn/off bipolar, gc Mesopic and photopic Mesopic and photopic

onlyonly Acuity 2.5Acuity 2.5mm

Fast ‘on’ and ‘off’Fast ‘on’ and ‘off’

Page 5: Light 1. Compare and contrast photopic and scotopic vision. 2. Why do we have both rods and cones? (N) 3. Discuss the significance of convergence and divergence.

Contrast sensitivity Contrast sensitivity functionfunction

Decreasingcontrast

Frequency