Issue Date: July 15, 2019

Nihonbashi Life Science Building 10F, 2-3-11 Nihonbashi Hon-cho, Chuo-ku, Tokyo, 103-0023, JapanTel: 81-3-3241-4911, Fax: 81-3-3241-3757 (9:00 to 17:00, Monday to Friday) www.link-j.org/en/

Life Science Innovation Network Japan, Inc. (LINK-J)

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Interaction and CollaborationDevelopment and Assistance

Creating New Life-Science Industries: A Platform for Human Interaction and Information Exchange

With progress in the life sciences, come improvements in human health. Despite the large numbers of people suffering from cancer and intractable conditions as well as the major risks posed to global health by infectious diseases, humanity continues to advance, overcoming sickness and preventing outbreaks.Japan is world renowned for leading basic research in the life sciences, yet the insights gained do not often readily lead to practical applications. In the highly specialized field of regenerative medicine, however, collaboration between industry, government, and academia is spurring rapid progress in this direction. We believe developments in regenerative medicine are opening up exciting opportunities in other life science fields to devise such practical applications.The life sciences constitute an interdisciplinary nexus linking all areas of scientific endeavor. They encompass medicine, the natural sciences, and engineering; such new technologies as IT and AI; and even social sciences and ethics. Reflecting this breadth of disciplines, it is not uncommon for insights or novel solutions to problems that have been exhaustively examined under a specialist lens to emerge from disparate fields. What a single person can do is limited. It is important to proactively promote collaboration with outside experts; that is, open innovation.The Life Science Innovation Network Japan (LINK-J) is the organization for real exchanges between people beyond fields, located in Nihonbashi, Tokyo where many businesses of the pharmaceutical industry and other life science industries can be found. Hopefully, major players such as universities, academic societies, public organizations, startups, large global companies and other businesses, and industry groups and overseas organizations will get together, interact with each other, and stimulate each other to create new values here in a range of fields including drug discovery, medical devices, and digital health.As the chairman of LINK-J, I am committed to helping people around the world live healthier lives.

The life sciences constitute an interdisciplinary nexus linking all areas of scientific endeavor.Actively promoting collaboration with outside specialists can be extremely valuable.

Chairman of the BoardHideyuki Okano, M.D., Ph.D.

Why in Nihonbashi ?The place where insights in life sciences coalesceNihonbashi, where the traditional rubs shoulders with the cutting edge, has historically been a wellspring of new value creation. Many of Japan’s representative pharmaceutical businesses have their main offices here, and insights in life sciences have accumulated in Nihonbashi since the Edo Period.

Centrally located in the heart of Tokyo, Nihonbashi boasts an inviting urban environment that offers a wide range of retail, lodging, and other facilities and is the focus of attention at both the domestic and international levels for the media, the general public, and investors. Nihonbashi was designated a global life science business hub by the Tokyo prefectural government in its Long-Term Vision for Tokyo that was formulated in 2014.

LINK-J is a platform for creating new life-science industries with the four functions of “bring together”, “connect”, “grow” and “take off”. LINK-J brings together a wide range of parties in the life sciences field. Creating new ideas, connecting people, and accelerating new initiatives.Providing an ecosystem to support open innovation.

Interaction and Collaboration Development and Assistance

LINK-J Networking Night with Supporters

The symposium for industry-university-government cooperation in regenerative medicine

SANDBOX,Scoop project Out of Box Consultation Room

● An exchange meeting with LINK-J supporters at Nihonbashi Life Science Building

● The opportunity for real exchanges is provided for many different players in the life science fields.

● Five hundred people participated in the large-scale symposium co-organized with the Japanese. Society of Regenerative Medicine (JSRM) and Forum for Innovative Regenerative Medicine (FIRM).

● Students and youth from different backgrounds, mainly including medical students, productively gather and cooperate.

● LINK-J supports a program where students and youth from different fields take on challenges in life sciences.

● This consultation session is intended for teachers, researchers, graduate school students and students involved in life science studies.

● Professionals stationed to work at the forefront of the pharmaceutical and medical industry provide support for problem solving.

UC San Diego- LINK-J Symposium

Medtech InnovationSymposium and Pich Life Science Awards LINK-J x TTT Awards

● LINK-J invites renowned researchers from the University of California, San Diego to organize events such as MICROBIOME-Latest Research and Development (2018) and Systems Biology, Bioinformatics and Big Data in Medicine and Drug Development (2019).

● The symposium is aimed at creating innovation in medtech, which encompasses medical devices.

● LINK-J organizes startups’ pitch events and exhibitions of posters showing the results of research and development.

● Promising businesses commended at the final of the BRAVE Acceleration Program organized by Beyond Next Ventures Inc.

● Invited to the Biocom Global Life Science Partnering Conference organized by Biocom affiliated with LINK-J.

● Sponsors Todai to Texas (TTT) (the project for supporting the participation of the startups related to The University of Tokyo in SXSW Trade Show held in Austin, Texas, U.S.A.)

Bring TogetherConnect

GrowTake Off

University Industry Group Business

Nihonbashi Life Science Building (LSB)

Nihonbashi Life Science Hub (HUB)

Nihonbashi Life Science Building2 (LSB2) Nihonbashi Life Science Building 2 (LSB2)

Nihonbashi Life Science Building (LSB)

Nihonbashi Life Science Hub (HUB)

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Life Science Innovation Network Japan, Inc. (LINK-J)

The Management Advisory Committee comprises experts from industry and academia who diligently employ their expertise and broad insight to support LINK-J’s activities.The Committee also provides strategic advice to the Board of Directors.

Directors and Auditors

Chairman of the Board Hideyuki Okano, M.D., Ph.D. Dean, Keio University Graduate School of Medicine Professor, Department of Physiology

Vice Chairman of the Board Yoshiki Sawa, M.D., Ph.D. Professor, Department of Cardiovascular Surgery,Osaka University Graduate School of Medicine

Director Takashi Ueda Executive Managing Officer, Mitsui Fudosan Co., Ltd.

Director Akihiko Soyama President and Chief Executive Officer of LINK-J

Auditor Yutaro Kikuchi Attorney at law, Kikuchi Sogo Law Office

Auditor Shigeru Sugimoto Managing partner, Sakura Horwath & Co.

Management Advisory Committee Members

The Management Advisory Committee comprises experts from industry and academia who diligently employ their expertise and broad insight to support LINK-J’s activities. The Committee also provides strategic advice to the Board of Directors.

Special AdvisorYoichiro MatsumotoPresident, Tokyo University of Science, Dr. Eng.

Special AdvisorShinya YamanakaDirector, Center for iPSCell Research andApplication (CiRA) Kyoto University, M.D., Ph.D., Professor

Special AdvisorPeter F. Cowhey

Dean, School of Global Policy & Strategy, University of California, San Diego

Advisor Shinji Asonuma Executive Vice-President for Industry-Government-Academia Collaboration, Kyoto University

Advisor Hironori Kasahara, Ph.D. Senior Executive Vice President for Research and IT Promotion

Advisor Hidetoshi Kotera Executive Director, RIKEN

Advisor Isao Teshirogi, Ph.D. President, The Federation of Pharmaceutical Manufacturers’ Associations of JAPAN (FPMAJ)President and CEO of Shionogi & Co., Ltd.

Advisor Yuzo Toda Chairman, Forum for Innovative Regenerative Medicine (FIRM)

Advisor George Nakayama President, Japan Pharmaceutical Manufacturers Association (JPMA)Charman and CEO, Daiichi Sankyo Co., Ltd.

Advisor Toshiaki Higashihara President & CEO, Hitachi, Ltd.

Advisor Masaaki Mizuno, M.D., Ph.D. Nagoya University Hospital Department of Advanced Medicine Center for Advanced medicine and Clinical Research Director , Clinical Professor

Advisor Yoshinori Yajima Director, Office of Cooperative Research and Development, Tohoku University

Advisor Masato Wakayama, D.Sc. Executive Vice President, Kyushu University

Advisor Toshiya Watanabe, Ph.D. The University of Tokyo Institute for Future Initiatives

Advisor Shinya Watanabe Chairman, the Japan Federation of Medical Devices Associations

Advisor Masanobu Komoda President and CEO, Mitsui Fudosan Co., Ltd.

ORGANIZATION SUPPORTERS

General Meeting

Governing Board

Executive Office

Auditor

ManagementAdvisory Committee

(as of May 1, 2019)

LINK-J has recruited a number of “supporters”, people with knowledge spanning diverse fields and whose skill sets range from research and development to management, law, and accounting. Our supporters, who include entrepreneurs and experts, participate in many of the events that we put together and offer one-on-one advice to LINK-J special members.

Aki Shimauchi Atsushi Usami, Ph.D. Daiki Moriyama Dr. Tomy Kamada Hajime Oshita Hayato WatanabeINDEE Medical, Inc. The University of Tokyo

Edge Capital Co., Ltd.Deloitte Tohmatsu Venture Support Co., Ltd.

TomyK Ltd. MedVenture Partners, Inc. Locust Walk Japan, LLC

Hiroaki Kitano, Ph.D. Hiroyuki Kanoh Ikkei Matsuda,Ph.D. & MBA

Jun Otomo, Ph.D. Keita Mori Kinji Fuchikami

The Systems BiologyInstitute

Forum for InnovativeRegenerative Medicine

Science, Art & Research for Reconstruction (SARR)

Hitachi, Ltd. SanBio Company Limited Mitsui & Co. GlobalInvestment, Inc.

Koichiro Tsujimaru, Ph.D. Masanori Akita Masashi Kiyomine Masashi Matsunaga,

Ph.D.

Masayuki Yokota Nobuhiko Hibara, Ph.D.

Tsujimaru International Patent Office

MTI Ltd. Kicker Ventures LLC BIOSPIRE JAPAN LTD. Tokyo Stock Exchange, Inc. Waseda Business School

Ryuji Hiramatsu Ph.D.

Shingo Tsuda Shunichi Takahashi, Ph.D. Takahiro Uchida,M.D. Ph.D., MSc.

Takashi Kiyoizumi, M.D., Ph.D.

Takato Noumi, Ph.D.

Foundation for Biomedical Research and Innovation at Kobe

INDEE Japan Ltd. Bayer Yakuhin, Ltd. Japanese Organization for Medical Device Development, Inc.

UC San Diego, Japan Forum for Innovation and Technology

FORESIGHT & LINX K.K.

Takuma Nakatsuka Taro Inaba Tohru Takashi, Ph.D. Toru J. Seo, Ph.D. Tsutomu Sugaya Tsuyoshi ItoPOC Clinical Research Inc. REMIGES Ventures Japan Agency for Medical

Research and DevelopmentPfizer Japan Inc. Nobelpharma Co., Ltd. Beyond Next Ventures

Ulrike Schaede Yo Iwami, M.D., Ph.D. Yohei Sawayama Yuji Yamamoto,M.D., MBA

UC San Diego, Japan Forumfor Innovation and Technology

MedPeer, Inc. Coral Capital 500 Startups Japan

MinaCare Co., Ltd.alphabetical sequence

(as of May 1, 2019)

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MEMBERSHIP Partners

They conclude memorandums for jointly hosting programs and events, exchanging publications, materials and information, providing services to its members, organizing reciprocal visits, co-hosting and jointly sponsoring activities, and cooperating for publicity.

University of California, San Diego (USA)

BIOCOM(USA) Eurobiomed(France) Kyoto Research Park Corp. (Japan) One Nucleus(UK)

Foundation for Biomedical Research and Innovation at Kobe (Japan)

Institute for Advanced Biosciences, Keio University (Japan)

MedCitty(UK) Kawasaki City (Japan) University of California, Los Angeles(USA)

Special Membership Type

Please choose from the following three types of special membership.

Membership Type Qualifi cationsEnrollment

FeeAnnual Fee

Membership Card

(1)

Special Membership A

Corp.

Corporations with 101 or more employees ¥100,000 ¥500,000 Ten cards*1

(2)

Special Membership B

Corp.

(i) Corporations with 100 or fewer employees

¥30,000 ¥120,000 Five cards*2

(ii) Non-profit organizations (Independent administrative agency, national

research and development agency, administrative agencies, educational

corporations, general corporations, public benefit corporations, social

welfare corporations, quasi-public bodies of diplomatic missions in Japan

and other such institutions)

(3)

Special Membership C

Individ.

(i) Doctors, Company related persons or employees, and other individuals

¥2,000

¥30,000

One card(ii) Related persons or employees of non-profi t organizations that correspond

to special membership B¥5,000

(iii) University students and graduate students ¥3,000

*1: Up to ten paid membership cards can be additionally issued. *2: Up to fi ve paid membership cards can be additionally issued.

The Benefi ts of Special Membership

You can receive the following benefi ts according to membership type.

● Participation in events and programs organized (at special membership prices)

● Temporary use of communication lounges (free) Corp. Individ.

● Notifi cation of events, etc. held by one member for others (Posts on the websites of LINK-J and Nihonbashi Life Science Business Hub and digital signage)

Corp. ● Reserved use of communication lounges for private parties, etc. (at special membership prices)

Corp.

● Post information on the LINK-J webite (message board). Corp. ● Use of conference rooms and temporary working rooms (at special membership prices)

Corp.

● Post company and group names as special members on the LINK-J website and pamphlets, etc.

Corp. ● Use of shared offi ces (applications must be made with payment)

Corp. Individ.

● Interactions with and introductions to other members Corp. Individ. ● Discussions with LINK-J’s supporters and use of advice, etc. Corp. Individ.

LINK-J’s Special Memberships A and B

Name of companyA&Z Law FirmAbiomed Japan K.K.Academic Industry Research Inc.ACTmed Co., Ltd.ADTHREE Publishing Co., Ltd.Advanced Gerontology In Next Generation Japan (AGING Japan)AETAS Pharma Co., Ltd.Agatha Inc.Ageing-Support Inc.Aikomi Inc.Alfresa CorporationAlliance Forum FoundationAnexAPep Inc.Antaa Co., Ltd.Aoyama Gakuin School CorporationAPRINOIA Therapeutics Inc.AQUA CPA OFFICEAsajes VenturesAsia Africa Investment and Consulting Pte. Ltd. (AAIC)Asia Med Market Access(AMMA)Association of Disclosure Business Offi cial ApprovalAstellas Pharma Inc.Axil Capital Advisors KK/ Axil Capital Partners LLPBachem Japan K.K.Baker & McKenzieBeyond Next VenturesBioARC Co. Ltd.BIOCOMBiodesign JapanBiogen Japan Ltd.BioLite Japan K.K.Biomedical Solutions Inc. BIOTUBE Co., Ltd.Boehringer Ingelheim Japan, Inc.Bourbon Biomedical Advanced Research Laboratories,Inc.Business Model Innovation Association (BMIA)Career Incubation, Inc.Carna Health Support LLCChiome Bioscience Inc.Chordia Therapeutics Inc.Chugai Pharmaceutical Co., Ltd. CM Plus CorporationCN Bio Innovations Ltd.Commons for Medicine and Engineering Japan (COME Japan) CROèe.INCCuorips Inc.CureApp, Inc.Daiichi Sankyo Co., Ltd.Decision Resources Japan K.K.Deep Intelligent PharmaDeloitte Tohmatsu Venture Support Co., Ltd.Delta-Fly Pharma, Inc. Demen Care LABORATORY Co., Ltd.Denka Company LimitedDENTSU Inc.DIA JapanDigital Garage, Inc.DyDo GROUP HOLDINGS, INC.Epigeneron Inc.Epsilon Molecular Engineering, Inc.Ernst & Young ShinNihon LLCEssence Co., Ltd. Exemedical Co., LtdFast Track Initiative, Inc.FIMECS, Inc.Forum for Innovative Regenerative Medicine (FIRM)Fourglobe Inc.

Fukushima Medical UniversityFuturedMe Co. Ltd.Gastheos Pharma Inc.General Incorporated Associations Health Care Stability and Regional Economy Vitalization ForumGeneral incorporated corporation ShirankaiGFE corporationGLOBIZZ CORP.GlyTech, Inc.GNI Ltd.Goryo Chemical, Inc. Graduate School of Medicine/ Faculty of Medicine, Osaka UniversityHakuju Owned Life Co., Ltd. Hiroshima UniversityHIROTSU BIO SCIENCE INC.Hitachi Chemical Co., Ltd.Hitachi Global Life Solutions, Inc. HMT, Inc. HPC SYSTEMS Inc.Human Life CORD Japan IncHuman Metabolome Technologies Inc.IBJ, Inc.iEducation (general incorporated association)INDEE Japan Ltd.Institute for Health Outcomes & Process Evaluation Research (iHope)institute of Sound Sleep Science (iSSS)iPS PORTAL Inc.Janssen Pharmaceutical K.K.Japan Aerospace Exploration AgencyJapan Agency for Medical Research and Development (AMED)Japan Association of Site Management OrganizationsJapan Biological Informatics Consortium (JBIC)Japan CRO AssociationJapan Manned Space Systems Corporation (JAMSS)Japan Medical Engineering InstituteJapan Microbiome Consortium(JMBC)Japan Ophthalmic Instruments Association Japan Research Institute, LimitedJapan Society of Clinical Trials and ResearchJapan Society of Pharmaceutical Machinery and Engineering (JSPME)Japanese Federation of Pharmaceutical and Cosmetic Industry Workers' UnionsJapanese Medical Specialty BoardJapanese Organization for Medical Device Development, Inc. (JOMDD)Japanese Society of Anti-Aging Medicine JCR Pharmaceuticals Co., Ltd.JITSUBO Co., Ltd. JOHNAN CORPORATIONJuntendo UniversityK Pharma Inc.K. ITO & ASSOCIATESKanagawa University of Human ServicesKeio Innovation Initiative, Inc.Keio UniversityKinoPharma, Inc.KINTARO Cells Power Co.Kitaie companyKyoto UniversityKyoto University Original Co., Ltd.Kyushu UniversityLiberoThera Co., Ltd.LibraMedicina company

Locust Walk Japan, LLCLUCA Science Inc.M Bio Technology Inc.Marubeni CorporationMatsumoto Global FoundationMatsumoto Trading Co., Ltd.Medical Collective Intelligence Co., Ltd. Medical Network system (MNES)Medicast, Inc.Medilabo RFP, Inc.MedPeer, Inc.Medrio Japan Inc.MedVenture Partners, Inc.MedVision CorporationMelody International Ltd. Mentis Cura Japan K.K.MeSCue JANUSYS CorporationMetcela Inc.Miibio, Inc.MinaCare Co., Ltd.Mindful Health Co., Ltd.Mitsubishi Research Institute, Inc. (MRI)Mitsubishi Tanabe Pharma CorporationMitsui Sumitomo Insurance Company, LimitedMizuho Securities Principal Investment Co., Ltd.Momotaro-Gene Inc. Murata Associates, Inc.MUSCA Inc.National University Corporation Hokkaido UniversityNational University Corporation Kanazawa UniversityNeU CorporationNew World Company Inc.Newton Biocapital PartnersNexredge, Inc.Nihonbashi Institute of Health Research Co., Ltd.Nikon CeLL innovation Co., Ltd.Nippon Medical SchoolNippon Telegraph and Telephone CorporationNobelpharma Co., Ltd.North American Science Associates, Inc. (NAMSA)notocord CorporationNS Materials Inc.Oishi kenko Inc.Olympus CorporationORTHOREBIRTH Co., Ltd. Otsuka PharmaceuticalOxford Nanopore TechnologiesP.J. Parker K.K.Patient Driven Academic LeaguePfi zer Japan Inc.Pharmaceutical Development Support CenterPHC Holdings CorporationPhosphorus Industry Development Organization of JapanPower Jinzai Co., Ltd.Promethera Biosciences SA Public University Corporation Yokohama City UniversityQuantum Biosystems Inc. Remohab Inc.Renascience Co., Ltd.Repertoire Genesis Inc.Research Coordinate, Inc.Ricoh Company, Ltd.RIKENRobotic Biology Institute Inc.Sakura Global Holding Co., LtdSAMURAI Biotech AssociationSanBio Company Limited

Santen Pharmaceutical Co., Ltd.Save Medical CorporationScience, Art & Research for Reconstruction (SARR, LLC.)Scientist.com GKShin Nippon Air Technologies Co., Ltd. Shinkowa Pharma Corp.Shokuno-Okusuri, Inc.Single Cell Technology CorpolationSK Management Ltd. SleepTechne Co., Ltd.Social Emergence SchoolSoundFun Inc. S'UIMINSUMITOMO CORPORATIONSumitomo Dainippon Pharma Co., Ltd. Sustainable Medicine, Inc.Sysmex CorporationTaisei CorporationTaiwan Carbon Nano Technology CorporationTaiwan Research-based Biopharmaceutical Manufacturers Association (TRPMA)Taiyo Life Insurance CompanyTakeda Pharmaceutical Co., Ltd.Takenaka CorporationTeeth Alignment Medical CorporationTeijin Pharma Limited.The Association for Preventive Medicine of JapanThe Center for Healthy Longevity Research and EducationThe Committee to Encourage New SurgeonsThe Federation of Pharmaceutical Manufacturers' Associations of JAPAN (FPMAJ)The Japan Pharmaceutical Manufacturers Association (JPMA)The Japanese Association of Pharmaceutical Medicine (JAPhMed)The Japanese Society for Regenerative Medicine (JSRM)The Jikei UniversityThe University of TokyoThe University of Tokyo Edge Capital Partners Co., Ltd.(UTEC)Thrive Bioscience,Inc.T-ICU Co., Ltd.TNAX Biopharma CorporationTohoku UniversityTokai Medical Products, Inc.Tokushima UniversityTokyo Metropolitan GovernmentToyota Research Institute Advanced Development, Inc.Trans Chromosomics Inc.Triple Regards LLCTsujimaru International Patent Offi ceUbie, Inc.Ubience Co. Ltd.UMI Co., Ltd.University of California, San DiegoUniversity of Occupational and Environmental Health, Japanupto4 Inc.US-Japan Medtech FrontiersVideoVisit Global LtdWaseda UniversityYamato Scientifi c Co., Ltd.

Corp. Individ.

* LINK-J’s Special Memberships C are not included. In Alphabetical order (as of June 1 2019)

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FACILITIES

Conference Rooms

We offer a variety of spaces in sizes ranging from those suitable for international conferences. We also provide equipment necessary for presentations, such as audio-visual equipment (partially paid rental service).

Nihonbashi Life Science Hub (HUB) Conference Room A

Nihonbashi Life Science Building (LSB)Conference Room 201

Nihonbashi Life Science Building 2(LSB2)Conference Room 313

Equipment and furniture

Furniture: desks, chairs, whiteboard, projector, screen, wireless microphone, cable-type microphone, microphone stand, stage, podium, wired LAN and wireless LANAdditional rental services are available: desks, chairs, whiteboard, projector, screen, TV conference system, sign stand and pointer* Different conference rooms have different furniture in various quantities. For more details, please see our website.

Usage Fees for Conference Rooms

Room Hours of Use Area (Square meters)

Maximum Capacity (Persons)

Special Membership A Special Membership BFees (yen) per hour Fees (yen) per hour

HUB 8F

Conference Room A

AM 9:00 to PM 9:00

244.0 m2 120 - 180 49,000 yen 24,500 yenConference Room B 77.7 m2 54 - 70 17,000 yen 8,500 yenConference Room C 44.4 m2 30 - 36 11,000 yen 5,500 yenConference Room D (B and C) 138.2 m2 81 - 110 28,000 yen 14,000 yenConference Room E (A, B and C) 383.8 m2 210 - 300 77,000 yen 38,500 yen

LSB

B1F Conference Room B103

AM 9:00 to PM 9:00

46.9 m2 24 5,000 yen 2,500 yen2F Large Conference Room 201 244.6 m2 150 45,000 yen 22,500 yen

3F

Conference Room 301 24.8 m2 12 3,500 yen 1,750 yenConference Room 302 50.2 m2 24 5,000 yen 2,500 yenConference Room 303 41.3 m2 18 4,000 yen 2,000 yenConference Room 311 17.0 m2 6 3,000 yen 1,500 yenStudio 312 25.4 m2 6 3,000 yen 1,500 yenConference Room 313 75.1 m2 36 7,000 yen 3,500 yenConference Room 314 42.3 m2 18 4,000 yen 2,000 yen

10F Conference Room 1004 AM 9:00 to PM 5:00 109.8 m2 55 15,000 yen 7,500 yen

LSB2 9F

Conference Room 901

AM 9:00 to PM 9:00

48.8 m2 24 5,000 yen 2,500 yenConference Room 902 18.1 m2 12 3,000 yen 1,500 yenConference Room 903 11.8 m2 6 3,000 yen 1,500 yenConference Room 904 11.7 m2 6 3,000 yen 1,500 yenConference Room 905 18.8 m2 12 3,500 yen 1,750 yenConference Room 906 7.6 m2 4 2,000 yen 1,000 yen

* [Excluding consumption tax, etc.]* A dedicated reservation system is available. Use the another reservation system for reservation for LSB2* Reservations may be accepted from one year before the date of use, up to two days before (or until the date of use for the LSB2 meeting rooms).* You can use LINK-J’s facilities on any day except for the New Year holidays. However, the facilities may be closed due to repairs and inspection, etc. * The minimum time for the use of conference rooms is two hours, with additional increments of thirty minutes after that.* The maximum limit for the use of conference rooms is 1,000 hours per year for each member. This limit may be changed without prior notice.* If you cancel your reservation due to personal circumstances, the following cancellation fees must be paid.

The facilities are available for use to facilitate, in a broad sense, the development of the life sciences industry.They may be used for meetings and seminars sponsored or organized by special members.

Communication Lounges

Our members can use the communication lounges free of charge. We prepare books related to the life sciences, free drinks and paid confectionery items in the area for members’ exclusive use. Please use these lounges for casual gatherings among LINK-J members and as third places. (You must carry your member card to access the area for members’ exclusive use.) A paid reservation is available for the communication lounges for receptions and parties, etc.

LSB Lounge on 10F LSB Lounge on 10F LSB Lounge on 1F

Ueno Building 8F HUB Foyer

Usage Fees for Communication Lounges

Room Hours of Use Area (Square meters) Maximum Capacity

Special Membership A Special Membership BFees (yen) per hour Fees (yen) per hour

HUB FoyerTemporary use*1

AM 9:00 to PM 9:00 153.4 m2

−

− −Reserved use*2 − −

LSBLounge on 10F

Temporary use*3 AM 8:00 to PM 10:00 205.2 m2 − −Reserved use PM 5:30 to PM 10:00 121.4 m2 30,000 yen 15,000 yen

Lounge on 1F Temporary use AM 8:00 to PM 10:00 81.0 m2 − −Ueno Lounge on 8F Temporary use AM9:00 to PM 9:00 68.2 m2 − −

* [Excluding consumption tax, etc.]* Use the resrvation system for reservation. Applications can be received one year prior to the day of use.* You can use LINK-J’s facilities on any day except for the New Year holidays. However, the facilities may be closed due to repairs and inspection, etc. * If you cancel your reservation due to personal circumstances, the following cancellation fees must be paid.* 1: If Conference Room E (A, B and C) is used, Foyer is also reserved. Therefore, Foyer cannot be used during that time.* 2: Only when using Conference Room E (A, B and C), are you able to reserve communication lounges. Hours of use include preparation and leaving.* 3: The communication lounges cannot be used during the night and when they are reserved.

Temporary Working Rooms

We offer a temporary business base in a space where the latest knowledge and information in the life sciences is assembled. Use these rooms as a paid service for a single day, up to seven days if necessary.

Usage Fees for Temporary Working Rooms

Room Hours of Use Area (Square meters) Maximum Capacity Special Membership A Special Membership B

Fees (yen) per hour Fees (yen) per hour

LSB 3FRoom 304 24 hour use is

available.17.2 m2

6 20,000 yen 10,000 yenRoom 305 16.8 m2

* [Excluding consumption tax, etc.]* The use of temporary working rooms must be done from 9:00 to 18:00, the hours of reception by attendants.* The upper limit for the use of temporary working rooms is eighty days per year for each member. This limit may be changed without prior notice.* Simultaneous reservations must be made up to twenty eight days.* You can use LINK-J’s facilities on any day except for the New Year holidays. However, the facilities may be closed due to repairs and inspection, etc. * If you cancel your reservation due to personal circumstances, the following cancellation fees must be paid.

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Life Science Innovation Network Japan, Inc. (LINK-J)

Address: Nihonbashi Life Science Building 10F, 2-3-11 Nihonbashi Hon-cho, Chuo-ku, Tokyo TEL: 81-3-3241-4911 FAX: 81-3-3241-3757

Guide Map

[1] Nihonbashi Life Science Building (LSB)LINK-J offi ce

2-3-11, Nihonbashi Honcho, Chuo-ku, Tokyo, 103-0023A three-minute walk from the A6 exit of Mitsukoshi Station on the Tokyo Metro Ginza and Hanzomon LinesA two-minute walk from the No. 5 exit of Shin-Nihonbashi Station on the JR Sobu Line (Rapid)

[2] Nihonbashi Life Science Hub (HUB) 1-5-5, Nihonbashi Muromachi, Chuo-ku, Tokyo 103-00228F., Muromachi Chibagin Mitsui BuildingDirectly connected from Mitsukoshi Station on the Tokyo Metro Ginza and Hanzomon LinesDirectly connected from Shin-Nihombashi Station on the JR Sobu Line (Rapid)A nine-minute walk from the southern exit of Kanda Station on the JR Yamanote, Keihin Tohoku and Chuo Rapid Lines

[3] Nihonbashi Life Science Building 2 (LSB2) 3-11-5, Nihonbashi Honcho, Chuo-ku, Tokyo, 103-0023

[4] Tosho Building 3-8-3, Nihonbashi Honcho, Chuo-ku, Tokyo, 103-0023

[5] MFPR Nihonbashi Honcho Building 3-7-2, Nihonbashi Honcho, Chuo-ku, Tokyo, 103-0023

[6] Ueno Building 1-9-10, Nihonbashi Horidomecho, Chuo-ku, Tokyo, 103-0012

[7] LAUNCH Building 3-7-6, Nihonbashi Ningyocho, Chuo-ku, Tokyo, 103-0013

[8] Fukushima Building 1-5-3, Nihonbashi Muromachi, Chuo-ku, Tokyo 103-0022

Service Offi ces

Service offi ces in Nihonbashi, Tokyo, gathering spots for the latest knowledge and information in the life sciences.

In order to respond to diverse needs, three types of usage plans are prepared. You can set the usage term fl exibly, you can also register as an registered offi ce. Also, because deposit is unnecessary, it is also attractive to be able to reduce the initial cost of use.

● Nihonbashi Life Science Building (LSB) ● Tosho Building ● Ueno Building

24 hour use is available Wi-Fi is available

Includes electricity and air conditioner charges

No deposit money needed

Reception room A multi-function printer is available with a shredder

A telephone booth is available

Company registration is possible

Personal booths Open desks Reception room

We off er booths that can secure privacy for from one-person to nine-person. Because the booths can be locked, you will have security.

We off er open seats for one person to use easily. Freely choose a seat. We also off er window-side seats where you can concentrate on your work eff ortlessly.

This room can be used when you have visitors. (Free of charge; there are limits on the number of uses)

Usage fees (monthly payment)

Open desk Personal booths [1-9 pers]From 30,000 yen From 70,000 yen

[Excluding consumption tax, etc.]

* You must pass a review to be allowed to use these facilities. In addition, you must become LINK-J member.

Offi ces

Offi ces for startups with equipment and an environment essential for scaling business and innovation.

● Nihonbashi Life Science Building (LSB) ● Nihonbashi Life Science Building 2 (LSB2) ● MFPR Nihonbashi Honcho Building ● Ueno Building ● LAUNCH Building ● Fukushima Building

Offi ce space Meeting space Woking Space

We off er a variety of spaces ranging from about 30 to 100 square meters in area. Freely use the lounge as a shared space.

We off er a meeting space that can be used when you have customers.

An open space is also available for works and meetings.

* You must separately sign a lease contract and pay a monthly fee and deposit. You must pass a review. In addition, you must become LINK- J member.

ACCESS

Starbucks Coffee■

Starbucks Coffee■

A5

Ningyocho Sta.A6

Edobashikita

■7-Eleven■7-Eleven

Horidome Children's Park

Horidome Children's Park

Doutor Coffee■Doutor Coffee■

Shinto ShrineShinto ShrineHoridomecho

Sobu Line (Rapid）

Nihonbashi Muromachi Mitsui Tower

④ Tosho Building

② Nihonbashi Life Science Hub8F., Muromachi Chibagin Mitsui Building

⑤ MFPR Nihonbashi Honcho Building

⑧ Fukushima Building

⑦ LAUNCH Building

⑥ Ueno Building

③ Nihonbashi Life Science Building 2

① Nihonbashi Life Science Building

① ② ③ ④ ⑤ ⑥ ⑧⑦