Li Conrad, DO, MA...NE and Dopamine •Improves attention, mood, reaction time, cognitive function...

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4/16/2019 1 Dr. Jane LiConrad, DO, MA Osteopathic Family Physician Specializing in Homeopathic Approaches MA Biology none

Transcript of Li Conrad, DO, MA...NE and Dopamine •Improves attention, mood, reaction time, cognitive function...

Page 1: Li Conrad, DO, MA...NE and Dopamine •Improves attention, mood, reaction time, cognitive function •Improves metabolism ... Founder of Homeopathic Medicine and human provings Homeo

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Dr.  Jane Li‐Conrad, DO,  MAOsteopathic Family Physician

Specializing in Homeopathic Approaches

MA Biology

none

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Learning objectives

Review healing philosophy

Review coffee chemistry

Review the coffee research from past and present 

How to use coffee safely for healing.

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.

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• Draft

• Sound

• Vibration

• Electricity

• Heat/Cold

• Damp

• Odors

• Light

• Chemicals

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From the collective human experience.

Individualizing the prescription

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• Dr. Samuel HAHNEMANN, MD 

• 1755‐1843 born in Germany, lived to 88 yo

• Degree in Chemistry 

First human proving in 1790

HUMAN PROVINGS: Study the physiological state of medicines on healthy persons. 

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Mental:

Improves concentration, and thinking

Emotional: 

Anxiety w/ restlessness

Joy

Physical:

Increased heart rate, urination

Increases stools

heat sensation

�.no such thing as “side” effects

Marijuana State

Exalted relaxed spirit

Clairvoyance

Absent minded

Hypersensitivity of senses

Increased appetite

Dry mouth and lips

Etc..

Coffee State

Excited state

Anxious

Mental clarity

Hypersensitivity of senses

Jittery

Palpitations

Etc…

Salt State

Weakness

Confusion

Dullness

Edema extremities

Thirst

Dry mouth and lips

Hypertension

Etc..

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Plants (coffee!)

Minerals

Animal substances

Poisons

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HPUS is an official compendium of homeopathic products that are recognized by the United States Federal Government as drugs.

Federal Food, Drug and Cosmetic Act of 1938 has been regulating the safety, manufacturing, marketing and sales of natural homeopathic products since 1938, after over  100 years of clinical use in USA alone.

HPUS monograph status indicates the remedy is standardized in identity, strength, quality, purity and packaging ( 1403 remedies).

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• One of many plant polyphenols but the most abundant one.

• Chlorogenic acid (CGA) comprises caffeic acid, ferulic acid, coumaricacid, and 3,4‐dimethoxycinnamic acid 

CGA is heat sensitive: content depends of growing conditions, light, temperature, weather and processing, roasting and preparation

50‐70% CGA destroyed in the roasting process.

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antioxidant,

anti‐inflammatory, 

antibacterial, 

cardioprotective, 

neuroprotective, 

modulates glucose and lipids

hepatoprotective

Adenosine receptor blocker: increases bioavailability of NT: 

NE and Dopamine•Improves attention, mood, reaction time, cognitive function

•Improves metabolism

•Improves exercise performance body

•Increases heart rate, conductivity, increases blood pressure & cholesterol

Increases gastric secretion 

Mobilizes calcium from bone or osteoporosis

Infertility

Poor pregnancy outcome (spontaneous abortion, malformation etc..)

ETC�

/

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other compounds�over 1000 types!

(diterpenes, coumarins, melanoidins etc�)

• trace amounts of vitamins /minerals 

(Mg, Phos, B vitamins�)

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1. Recognize toxicity or state

2. Suppress symptoms

3. Recognize cures

4. Support symptoms

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1. Recognize toxicity

2. Suppress symptoms

3. Recognize cures

4. Support symptoms

Drugs suppress  homeostasis

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1. Recognize toxicity/state

2. Suppress symptoms

3. Recognize cures

4. Support symptoms

1. Recognize toxicity/states

2. Suppress symptoms

3. Recognize cures

4. Support symptoms or symptom totality

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Homeostasis or  Vital Force• Symptoms have purpose.• Reactions occur to save the whole organism while parts suffer.

Disease affects the many parts of the organism

Study all imbalanced parts

Find a remedy that is the best mimic of the totality

Drug state to fit the disease state

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• Dr. Samuel HAHNEMANN, MD 

• 1755‐1843 born in Germany, lived to 88 yo

• Degree in Chemistry 

Founder of Homeopathic Medicine  and human provings

Homeo means similar

Pathos means suffering

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First Homeopathic physicians came to the USA from Europe

and began practicing homeopathic medicine 1825.

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NOT NATUROPATHIC SUPPLEMENTS!

Uses law of healing coined “the law of similars”

Uses one remedy to that best mimics the unique state�totality of strong and peculiar constitutional imbalances

Uses knowledge of provings and cured clinical cases

Uses minimum clinically effective dose

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1. The body is one unit: body, mind and spirit.

2. The body is capable of self regulating, self healing and maintenance given proper support. Vital Force

3. Structure and function are reciprocally interrelatedDysfunctions are observable using 5 senses.

4. Rational treatments are individualized for unique patient and based on 1‐3.

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It is a drug

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Overseer (not blinded) 

Drug: dose, potency, repetition

Administrator of drug or placebo is blinded.

20‐30 Provers are blinded

Groups of provers given placebo (20%) 

Groups of provers given drug

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STATE Before drug 

Review health history

Body habitus

Temperament

Environment sensitivity

Mental state

Emotional state

Physical state in detail

After drug (coffea 12 c or 30 c)

Mental state changes

Emotional state changes

Physical state changes

Location

Sensation

Concomitants

Modalities

Aggravation of chronic complaint

Return of old symptom

Improved or cured symptom

Change in susceptibilities, emotions

No change

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Journals reviewed to understand strength of symptoms, details of each symptoms, who most susceptible and confirm prevalence of symptoms.

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1. HOMEOPATHIC REPERTORY 

Book of organized and classified symptoms

with grade for each remedy.

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Grade 4 ALL provers / resolved the symptom in at least 3 patients.

Grade 3 At least 50% of provers / resolved the symptom for 3 patients.

Grade 2 LESS than 50% of provers / resolved the symptom for 3 patients.

Grade 1 At least one prover / resolved in at least 3 patients. 

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2. HOMEOPATHIC MATERIA MEDICA

Detailed information on each remedy.

Source, name, effects on the human body in general and on particular areas, indications for their application, cured symptoms

Collective material from physician journals and provings

Collection of all provings up to 1879

Explains who did provings, and in which journals they are published, how the provings were done (tincture drops or doses used)

792 remedies

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Collection of mainly cured clinical symptoms drawn from 60 sources

1100 authors, 

430 remedies

45 journals and periodicals (22 USA, 16 German, 4 French, 2 British, 1 indian)

11 general and clinical materia medicas

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CONVENTIONAL

Coffee as a drink

Epidemiological, case reports, small studies, cohort studies, review of literature etc.

Effect on  part or name of a disease

HOMEOPATHIC

Coffee in standard homeopathic dilution form

Effect on whole organism (state)

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CONVENTIONAL RESEARCH

coffee was shown to improve mood in small study.

coffee aroma was shown in small study to trigger emotions and evoke memories.

sense of joy

unpleasant events seem pleasant

• sympathy more active

• external objects excite a feeling of pleasure

• disagreeable recollections cease

• Weeping, complaining with fear of death, throws himself about in anguish.

HOMEOPATHIC RESEARCH

coffee improves brain function —memory, vigilance, reaction times and general mental function in several studies.

• rapid stream of imagination

• stores of memory spring into our mouth causing, loquacity, hurried chattering and letting things escape from our lips, things we ought not to have spoken about.

• hasty disclosures and resolves

• immature judgments

• theatrical behavior

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Conventional Research

A potential lowered risk in developing neurodegenerative diseases such as Alzheimers disease, Parkinsons disease and multiple sclerosis was found in several epidemiological studies.

Reduced cognitive decline measures were found in Alzheimers patients with 4‐6 cups of coffee daily.

A potential lowered risk in developing neurodegenerative diseases such as Alzheimers disease, Parkinsons disease and multiple sclerosis was found in several epidemiological studies.

Reduced cognitive decline measures were found in Alzheimers patients with 4‐6 cups of coffee daily.

active memory: recalls old memories easily

easy comprehension, clearness of thoughts, mentally alert

abundant ideas, rapid thoughts

• increased power to think and debate

• recall things not thought of in years

dullness or prostration of mind

Homeopathic Research

sleepless from overexcitement , overactive body or mind,

sleepless from excitement, agreeable surprise, or excess joy

insomnia with palpitations and nervousness

when finally falls asleep, has terrifying dreams or long vivid dreams

With rush of thoughts

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Review of literature: probably no association between CHD and coffee intake; or there may be a potential benefit.

An average of 2 cups a day may protect against heart failure particularly for women

Review of literature: probably no association between CHD and coffee intake; or there may be a potential benefit.

An average of 2 cups a day may protect against heart failure particularly for women

edema with heart complaints

dilation of heart

weakness felt in the heart

epidemiological studies: consumption of coffee does not appear to cause heart arrhythmias in those with a healthy heart. 

incidence of atrial fibrillation is not increased by coffee consumption 

and 4 to 5 cups of coffee may reduce risk of AF.

restlessness, excitable and nervousness with palpitations

palpitations from sudden joy during pain

palpitations from warmth of sun

tumultuous palpitation with trembling limbs

plethora with palpitation

rapid irregular heart beat, with strong frequent pulse

Sl l

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Several epidemiological studies:

Consumption of 3–4 cups of coffee per day decreased the risk of hypertension in non‐smoking men and women.

Several epidemiological studies:

Consumption of 3–4 cups of coffee per day decreased the risk of hypertension in non‐smoking men and women.

fainting from excitement, joy, fear, pain or during menopause

faints easily

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Small study: coffee intake around 5 cups per day causes a small elevation in BP (approximately 2/1 mmHg)

appears to play an insignificant role in the development of hypertension in epidemiological studies.

sudden rise in blood pressure

heat in face with palpitation

tension in arteries

Many epidemiological studies confirmed coffee consumption in men and women alike reduced the risk of non hemorrhagic stroke by 12% with consumption of 4‐5 cups daily. Over 6 cups a day further reduced risk to 20‐25% .

Many epidemiological studies confirmed coffee consumption in men and women alike reduced the risk of non hemorrhagic stroke by 12% with consumption of 4‐5 cups daily. Over 6 cups a day further reduced risk to 20‐25% .

overpowered with sleep before stroke

overexcited, talkative, full of fear in person with stroke symptoms

head congestion with stroke

nervous stroke with trembling of extremities

stroke in drunkards

threatening stroke

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Epidemiological studies. coffee consumption in moderation, is safe and is beneficial in both healthy persons as well as patients with high BP, CVD, HF, cardiac arrhythmias or DM. Therefore, coffee restriction is not warranted for these patients, although some caution should be exercised.

Epidemiological studies. coffee consumption in moderation, is safe and is beneficial in both healthy persons as well as patients with high BP, CVD, HF, cardiac arrhythmias or DM. Therefore, coffee restriction is not warranted for these patients, although some caution should be exercised.

Epidemiological studies: Coffee drinking may be inversely associated with all cause mortality, including among those drinking 8 or more cups per day and those with genetic polymorphisms indicating slower or faster caffeine metabolism.

Other studies showed conflicting conclusions but attributed it to the the fact that most of the coffee drinker studied were sedentary smokers as well.

Epidemiological studies: Coffee drinking may be inversely associated with all cause mortality, including among those drinking 8 or more cups per day and those with genetic polymorphisms indicating slower or faster caffeine metabolism.

Other studies showed conflicting conclusions but attributed it to the the fact that most of the coffee drinker studied were sedentary smokers as well.

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Several epidemiological studies. High intakes of coffee(4‐6 cups qd) or decaffeinated coffee may reduce the risk of Type 2 diabetes. 

Coffee lowered glucose 30 minutes after coffee in small studies.

No effect of fasting blood sugar with daily coffee use in small study.

Several epidemiological studies. High intakes of coffee(4‐6 cups qd) or decaffeinated coffee may reduce the risk of Type 2 diabetes. 

Coffee lowered glucose 30 minutes after coffee in small studies.

No effect of fasting blood sugar with daily coffee use in small study.

waking w/thirst at night 

glucosuria

frequent pale, colorless urine

profuse or scanty urination

Excessive hunger with hurried eating 

Conflicting results in population based studies between coffee and headache

Small study showed reduced migraines when stopping coffee.

Conflicting results in population based studies between coffee and headache

Small study showed reduced migraines when stopping coffee.

Migraine starts in the morning after waking and increases little by little

head pain, sensation as if a nail, worse in open air

head pain worse from footsteps, from noise, conversation

Headache from pleasant surprise restlessness, anxiety

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neuralgias of head, ear , sciatica with restlessness and insomnia

Extremely painful neuralgias

worse draft of air or cold exposure

Neuralgias with fear of death and restlessness

convulsion from laughing

convulsion with twitching during menses

Jerking and twitching of arms and hands

Puerperal convulsions with extreme excitability 

Case report of a patient who experienced a dramatic decrease in the frequency of his partial seizures after stopping coffee ingestion.

In other words, coffee may cause seizures or at least make them worse in some people.

Case report of a patient who experienced a dramatic decrease in the frequency of his partial seizures after stopping coffee ingestion.

In other words, coffee may cause seizures or at least make them worse in some people.

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4‐6 cups of coffee per day may reduce the risk for numerous cancers in review of literature and several epidemiological studies. 

Hepatocellular: Studies show that coffee drinkers have up to a 40% lower risk of liver cancer..

Invasive ovarian cancer: a reduced risk of developing.

Endometrial cancer: reduced risk

Breast cancer reduction: has been documented in several studies.

Colorectal: one study in 489,706 people found that those who drank 4–5 cups of coffee per day had a 15% lower risk of colorectal cancer.

4‐6 cups of coffee per day may reduce the risk for numerous cancers in review of literature and several epidemiological studies. 

Hepatocellular: Studies show that coffee drinkers have up to a 40% lower risk of liver cancer..

Invasive ovarian cancer: a reduced risk of developing.

Endometrial cancer: reduced risk

Breast cancer reduction: has been documented in several studies.

Colorectal: one study in 489,706 people found that those who drank 4–5 cups of coffee per day had a 15% lower risk of colorectal cancer.

Small study: higher coffee consumption was associated with a small but significant reduction in number of teeth with periodontal bone loss. 

Review of several studies. coffee consumption may or may not be associated with reduction in bone mineral density. Conflicting studies.

Small study: higher coffee consumption was associated with a small but significant reduction in number of teeth with periodontal bone loss. 

Review of several studies. coffee consumption may or may not be associated with reduction in bone mineral density. Conflicting studies.

tooth pain better with ice cold water, worsens as soon it warms.

pains in bones of leg and long bones

slight draft or air increases pain in extremity

caries of bones

• teeth decay

• black and yellow teeth

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morning asthma

oppression of chest or tightness in chest or trachea constriction

must move, restlessness in asthma, wants to move continuously

asthma from emotional excitementwith anxious respiration

hysterical or gasping respiration

Coffee may protect against cirrhosis, especially  alcoholic cirrhosis — people who drink 4 or more cups per day have up to an 80% lower risk in epidemiological studies .

Prostration of mind from alcoholic drinks

Alcoholic drinks agg stomach

Atrophy of liver

Burning pain in liver

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Coffee promotes GERD but is not associated with dyspepsia. 

Coffee stimulates gallbladder contraction by increasing CCK

Coffee may or may not slow gastric emptying and small bowel transit.

Coffee promotes GERD but is not associated with dyspepsia. 

Coffee stimulates gallbladder contraction by increasing CCK

Coffee may or may not slow gastric emptying and small bowel transit.

increased or decreased appetite for food or drink

stomach pain in epigastric region (burning or cramping) with nausea and vomiting, disgust for food, vomiting of mucous

stomach feels overloaded, clothing feels oppressive,

violent burping of sour taste

Coffee increased colorectal activity in some studies.

• diarrhea or loose, more frequent stool 

• diarrhea from worry or sudden joy

constipation (less common) with hemorrhoids

Diarrhea from cholera and diarrhea from unexpected news

Extremely violet colic, excessive pain with anxiety with loud crying 

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Epidemiological studies. coffee intake was associated with lower rosacea risk. Participants who drank over 4 cups per day were less likely to develop rosacea.

Case reports of allergic reactions to coffee include: skin rashes, such as hives or blotches of red skin.

Epidemiological studies. coffee intake was associated with lower rosacea risk. Participants who drank over 4 cups per day were less likely to develop rosacea.

Case reports of allergic reactions to coffee include: skin rashes, such as hives or blotches of red skin.

urticarial‐like eruptions with itching

itching skin during menses

rash from excitement

draft of air, increases painful erysipelas in extremities.

• Quick as lightening excitement or desire from moderate exciting causes (premature ejaculation)

• Excitation of the genitals to complete ecstasy becomes the work of a few seconds

• Ejaculation of semen is almost uncontrolled

• Desire is 10‐15 seconds too soon in both sexes

• Nocturnal emissions of semen followed by irritability

• Nightly involuntary emissions with frequent erections

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Coition painful at climax

Heavy menses with large black clots with restlessness from pain

Too frequent, protracted, heavy menses in nervous women with bright red face

Increased sexual desire during menses 

• ineffectual labor with irregular contractionswith extreme fear of death, with great excitement of nervous system, any noise aggravates the labor pains

• cries out, sees vision and hears noises not there.

fear of death with labor pain

• labor pain worse after good news

lactation disappears from excitement in nervous person

• puerperal convulsions with extreme excitability

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Heart: Palpitations from sudden emotions, weak feeling in heart , 

Circulation: febrile warmth, plethora, fainting

Muscles: Mobility of muscles increased

Sexual: desire excited

Female: heavy black menstrual bleeding, metrorrhagia, hemorrhage

Labor: excessive labor pain contractions

Nervous system: neuralgia, increased pain, anxiety, fear of death, seizures

GI: increased stool, increased gastric acid secretion

Skin: various rashes, hives, measles‐like rash

Etc…

Sudden emotions causes various ailments

(HA, palpitations, asthma, suppressed lactation..) in a coffee state

Restless, anxious state, racing thoughts, fear of death, anguish with neuralgia

Worse heat of sun and in a coffee state

(palpitations, headaches)

Sensitivity to pain, esp of nerves, worse draft of air

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• Facial neuralgias, sciatica

• Seizures

• Asthma

• Colic

• Diarrhea from excitement, 

• Ecstasy, excitement, 

• Migraine headache,

• Palpitation or hypersensitivity of the heart

• Ill effects of overjoy

• Labor pains 

• Heavy menstrual bleeding, 

• Shock with anxiety and restlessness 

• Insomnia 

• Toothache

• Impotence

Take a homeopathic case

Use coffee as medicine if it mimics the 

CONSTITUTIONAL 

tendencies of the person and pattern of disease

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Cups of coffee. 

Test blood sugar with and without coffee.

Have patient note how they feel on coffee. Each person reacts differently to coffee. Remember coffee really is a medicine. Drink in moderation.

Filter coffee using paper filter, if worry about elevated cholesterol to remove diterpenes from coffee.

No consensus on coffee in conventional literature

As Family Physicians, we need more tools and choices to improve the comfort of our patients.

Learn more at American Institute for Homeopathy

Page 51: Li Conrad, DO, MA...NE and Dopamine •Improves attention, mood, reaction time, cognitive function •Improves metabolism ... Founder of Homeopathic Medicine and human provings Homeo

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Dr. Jane Li‐Conrad D.O.

Tel 440‐334‐6200

www.remedyjane.com

Marijuana State

Exalted spirit

Clairvoyance

Absent minded

Hypersensitivity of senses

Increased appetite

Dry mouth and lips

Etc..

Coffee State

Excited state

Anxious

Mental clarity

Hypersensitivity of senses

Jittery

Palpitations

Etc…

Salt State

Weakness

Confusion

Dullness

Edema extremities

Thirst

Dry mouth and lips

Hypertension

Etc..