Li Conrad, DO, MA...NE and Dopamine •Improves attention, mood, reaction time, cognitive function...
Transcript of Li Conrad, DO, MA...NE and Dopamine •Improves attention, mood, reaction time, cognitive function...
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Dr. Jane Li‐Conrad, DO, MAOsteopathic Family Physician
Specializing in Homeopathic Approaches
MA Biology
none
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Learning objectives
Review healing philosophy
Review coffee chemistry
Review the coffee research from past and present
How to use coffee safely for healing.
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• Draft
• Sound
• Vibration
• Electricity
• Heat/Cold
• Damp
• Odors
• Light
• Chemicals
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From the collective human experience.
Individualizing the prescription
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• Dr. Samuel HAHNEMANN, MD
• 1755‐1843 born in Germany, lived to 88 yo
• Degree in Chemistry
First human proving in 1790
HUMAN PROVINGS: Study the physiological state of medicines on healthy persons.
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Mental:
Improves concentration, and thinking
Emotional:
Anxiety w/ restlessness
Joy
Physical:
Increased heart rate, urination
Increases stools
heat sensation
�.no such thing as “side” effects
Marijuana State
Exalted relaxed spirit
Clairvoyance
Absent minded
Hypersensitivity of senses
Increased appetite
Dry mouth and lips
Etc..
Coffee State
Excited state
Anxious
Mental clarity
Hypersensitivity of senses
Jittery
Palpitations
Etc…
Salt State
Weakness
Confusion
Dullness
Edema extremities
Thirst
Dry mouth and lips
Hypertension
Etc..
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Plants (coffee!)
Minerals
Animal substances
Poisons
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HPUS is an official compendium of homeopathic products that are recognized by the United States Federal Government as drugs.
Federal Food, Drug and Cosmetic Act of 1938 has been regulating the safety, manufacturing, marketing and sales of natural homeopathic products since 1938, after over 100 years of clinical use in USA alone.
HPUS monograph status indicates the remedy is standardized in identity, strength, quality, purity and packaging ( 1403 remedies).
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• One of many plant polyphenols but the most abundant one.
• Chlorogenic acid (CGA) comprises caffeic acid, ferulic acid, coumaricacid, and 3,4‐dimethoxycinnamic acid
CGA is heat sensitive: content depends of growing conditions, light, temperature, weather and processing, roasting and preparation
50‐70% CGA destroyed in the roasting process.
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antioxidant,
anti‐inflammatory,
antibacterial,
cardioprotective,
neuroprotective,
modulates glucose and lipids
hepatoprotective
Adenosine receptor blocker: increases bioavailability of NT:
NE and Dopamine•Improves attention, mood, reaction time, cognitive function
•Improves metabolism
•Improves exercise performance body
•Increases heart rate, conductivity, increases blood pressure & cholesterol
Increases gastric secretion
Mobilizes calcium from bone or osteoporosis
Infertility
Poor pregnancy outcome (spontaneous abortion, malformation etc..)
ETC�
/
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other compounds�over 1000 types!
(diterpenes, coumarins, melanoidins etc�)
• trace amounts of vitamins /minerals
(Mg, Phos, B vitamins�)
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1. Recognize toxicity or state
2. Suppress symptoms
3. Recognize cures
4. Support symptoms
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1. Recognize toxicity
2. Suppress symptoms
3. Recognize cures
4. Support symptoms
Drugs suppress homeostasis
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1. Recognize toxicity/state
2. Suppress symptoms
3. Recognize cures
4. Support symptoms
1. Recognize toxicity/states
2. Suppress symptoms
3. Recognize cures
4. Support symptoms or symptom totality
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Homeostasis or Vital Force• Symptoms have purpose.• Reactions occur to save the whole organism while parts suffer.
Disease affects the many parts of the organism
Study all imbalanced parts
Find a remedy that is the best mimic of the totality
Drug state to fit the disease state
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• Dr. Samuel HAHNEMANN, MD
• 1755‐1843 born in Germany, lived to 88 yo
• Degree in Chemistry
Founder of Homeopathic Medicine and human provings
Homeo means similar
Pathos means suffering
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First Homeopathic physicians came to the USA from Europe
and began practicing homeopathic medicine 1825.
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NOT NATUROPATHIC SUPPLEMENTS!
Uses law of healing coined “the law of similars”
Uses one remedy to that best mimics the unique state�totality of strong and peculiar constitutional imbalances
Uses knowledge of provings and cured clinical cases
Uses minimum clinically effective dose
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1. The body is one unit: body, mind and spirit.
2. The body is capable of self regulating, self healing and maintenance given proper support. Vital Force
3. Structure and function are reciprocally interrelatedDysfunctions are observable using 5 senses.
4. Rational treatments are individualized for unique patient and based on 1‐3.
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It is a drug
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Overseer (not blinded)
Drug: dose, potency, repetition
Administrator of drug or placebo is blinded.
20‐30 Provers are blinded
Groups of provers given placebo (20%)
Groups of provers given drug
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STATE Before drug
Review health history
Body habitus
Temperament
Environment sensitivity
Mental state
Emotional state
Physical state in detail
After drug (coffea 12 c or 30 c)
Mental state changes
Emotional state changes
Physical state changes
Location
Sensation
Concomitants
Modalities
Aggravation of chronic complaint
Return of old symptom
Improved or cured symptom
Change in susceptibilities, emotions
No change
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Journals reviewed to understand strength of symptoms, details of each symptoms, who most susceptible and confirm prevalence of symptoms.
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1. HOMEOPATHIC REPERTORY
Book of organized and classified symptoms
with grade for each remedy.
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Grade 4 ALL provers / resolved the symptom in at least 3 patients.
Grade 3 At least 50% of provers / resolved the symptom for 3 patients.
Grade 2 LESS than 50% of provers / resolved the symptom for 3 patients.
Grade 1 At least one prover / resolved in at least 3 patients.
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2. HOMEOPATHIC MATERIA MEDICA
Detailed information on each remedy.
Source, name, effects on the human body in general and on particular areas, indications for their application, cured symptoms
Collective material from physician journals and provings
Collection of all provings up to 1879
Explains who did provings, and in which journals they are published, how the provings were done (tincture drops or doses used)
792 remedies
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Collection of mainly cured clinical symptoms drawn from 60 sources
1100 authors,
430 remedies
45 journals and periodicals (22 USA, 16 German, 4 French, 2 British, 1 indian)
11 general and clinical materia medicas
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CONVENTIONAL
Coffee as a drink
Epidemiological, case reports, small studies, cohort studies, review of literature etc.
Effect on part or name of a disease
HOMEOPATHIC
Coffee in standard homeopathic dilution form
Effect on whole organism (state)
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CONVENTIONAL RESEARCH
coffee was shown to improve mood in small study.
coffee aroma was shown in small study to trigger emotions and evoke memories.
sense of joy
unpleasant events seem pleasant
• sympathy more active
• external objects excite a feeling of pleasure
• disagreeable recollections cease
• Weeping, complaining with fear of death, throws himself about in anguish.
HOMEOPATHIC RESEARCH
coffee improves brain function —memory, vigilance, reaction times and general mental function in several studies.
• rapid stream of imagination
• stores of memory spring into our mouth causing, loquacity, hurried chattering and letting things escape from our lips, things we ought not to have spoken about.
• hasty disclosures and resolves
• immature judgments
• theatrical behavior
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Conventional Research
A potential lowered risk in developing neurodegenerative diseases such as Alzheimers disease, Parkinsons disease and multiple sclerosis was found in several epidemiological studies.
Reduced cognitive decline measures were found in Alzheimers patients with 4‐6 cups of coffee daily.
A potential lowered risk in developing neurodegenerative diseases such as Alzheimers disease, Parkinsons disease and multiple sclerosis was found in several epidemiological studies.
Reduced cognitive decline measures were found in Alzheimers patients with 4‐6 cups of coffee daily.
active memory: recalls old memories easily
easy comprehension, clearness of thoughts, mentally alert
abundant ideas, rapid thoughts
• increased power to think and debate
• recall things not thought of in years
dullness or prostration of mind
Homeopathic Research
sleepless from overexcitement , overactive body or mind,
sleepless from excitement, agreeable surprise, or excess joy
insomnia with palpitations and nervousness
when finally falls asleep, has terrifying dreams or long vivid dreams
With rush of thoughts
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Review of literature: probably no association between CHD and coffee intake; or there may be a potential benefit.
An average of 2 cups a day may protect against heart failure particularly for women
Review of literature: probably no association between CHD and coffee intake; or there may be a potential benefit.
An average of 2 cups a day may protect against heart failure particularly for women
edema with heart complaints
dilation of heart
weakness felt in the heart
epidemiological studies: consumption of coffee does not appear to cause heart arrhythmias in those with a healthy heart.
incidence of atrial fibrillation is not increased by coffee consumption
and 4 to 5 cups of coffee may reduce risk of AF.
restlessness, excitable and nervousness with palpitations
palpitations from sudden joy during pain
palpitations from warmth of sun
tumultuous palpitation with trembling limbs
plethora with palpitation
rapid irregular heart beat, with strong frequent pulse
Sl l
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Several epidemiological studies:
Consumption of 3–4 cups of coffee per day decreased the risk of hypertension in non‐smoking men and women.
Several epidemiological studies:
Consumption of 3–4 cups of coffee per day decreased the risk of hypertension in non‐smoking men and women.
fainting from excitement, joy, fear, pain or during menopause
faints easily
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Small study: coffee intake around 5 cups per day causes a small elevation in BP (approximately 2/1 mmHg)
appears to play an insignificant role in the development of hypertension in epidemiological studies.
sudden rise in blood pressure
heat in face with palpitation
tension in arteries
Many epidemiological studies confirmed coffee consumption in men and women alike reduced the risk of non hemorrhagic stroke by 12% with consumption of 4‐5 cups daily. Over 6 cups a day further reduced risk to 20‐25% .
Many epidemiological studies confirmed coffee consumption in men and women alike reduced the risk of non hemorrhagic stroke by 12% with consumption of 4‐5 cups daily. Over 6 cups a day further reduced risk to 20‐25% .
overpowered with sleep before stroke
overexcited, talkative, full of fear in person with stroke symptoms
head congestion with stroke
nervous stroke with trembling of extremities
stroke in drunkards
threatening stroke
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Epidemiological studies. coffee consumption in moderation, is safe and is beneficial in both healthy persons as well as patients with high BP, CVD, HF, cardiac arrhythmias or DM. Therefore, coffee restriction is not warranted for these patients, although some caution should be exercised.
Epidemiological studies. coffee consumption in moderation, is safe and is beneficial in both healthy persons as well as patients with high BP, CVD, HF, cardiac arrhythmias or DM. Therefore, coffee restriction is not warranted for these patients, although some caution should be exercised.
Epidemiological studies: Coffee drinking may be inversely associated with all cause mortality, including among those drinking 8 or more cups per day and those with genetic polymorphisms indicating slower or faster caffeine metabolism.
Other studies showed conflicting conclusions but attributed it to the the fact that most of the coffee drinker studied were sedentary smokers as well.
Epidemiological studies: Coffee drinking may be inversely associated with all cause mortality, including among those drinking 8 or more cups per day and those with genetic polymorphisms indicating slower or faster caffeine metabolism.
Other studies showed conflicting conclusions but attributed it to the the fact that most of the coffee drinker studied were sedentary smokers as well.
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Several epidemiological studies. High intakes of coffee(4‐6 cups qd) or decaffeinated coffee may reduce the risk of Type 2 diabetes.
Coffee lowered glucose 30 minutes after coffee in small studies.
No effect of fasting blood sugar with daily coffee use in small study.
Several epidemiological studies. High intakes of coffee(4‐6 cups qd) or decaffeinated coffee may reduce the risk of Type 2 diabetes.
Coffee lowered glucose 30 minutes after coffee in small studies.
No effect of fasting blood sugar with daily coffee use in small study.
waking w/thirst at night
glucosuria
frequent pale, colorless urine
profuse or scanty urination
Excessive hunger with hurried eating
Conflicting results in population based studies between coffee and headache
Small study showed reduced migraines when stopping coffee.
Conflicting results in population based studies between coffee and headache
Small study showed reduced migraines when stopping coffee.
Migraine starts in the morning after waking and increases little by little
head pain, sensation as if a nail, worse in open air
head pain worse from footsteps, from noise, conversation
Headache from pleasant surprise restlessness, anxiety
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neuralgias of head, ear , sciatica with restlessness and insomnia
Extremely painful neuralgias
worse draft of air or cold exposure
Neuralgias with fear of death and restlessness
convulsion from laughing
convulsion with twitching during menses
Jerking and twitching of arms and hands
Puerperal convulsions with extreme excitability
Case report of a patient who experienced a dramatic decrease in the frequency of his partial seizures after stopping coffee ingestion.
In other words, coffee may cause seizures or at least make them worse in some people.
Case report of a patient who experienced a dramatic decrease in the frequency of his partial seizures after stopping coffee ingestion.
In other words, coffee may cause seizures or at least make them worse in some people.
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4‐6 cups of coffee per day may reduce the risk for numerous cancers in review of literature and several epidemiological studies.
Hepatocellular: Studies show that coffee drinkers have up to a 40% lower risk of liver cancer..
Invasive ovarian cancer: a reduced risk of developing.
Endometrial cancer: reduced risk
Breast cancer reduction: has been documented in several studies.
Colorectal: one study in 489,706 people found that those who drank 4–5 cups of coffee per day had a 15% lower risk of colorectal cancer.
4‐6 cups of coffee per day may reduce the risk for numerous cancers in review of literature and several epidemiological studies.
Hepatocellular: Studies show that coffee drinkers have up to a 40% lower risk of liver cancer..
Invasive ovarian cancer: a reduced risk of developing.
Endometrial cancer: reduced risk
Breast cancer reduction: has been documented in several studies.
Colorectal: one study in 489,706 people found that those who drank 4–5 cups of coffee per day had a 15% lower risk of colorectal cancer.
Small study: higher coffee consumption was associated with a small but significant reduction in number of teeth with periodontal bone loss.
Review of several studies. coffee consumption may or may not be associated with reduction in bone mineral density. Conflicting studies.
Small study: higher coffee consumption was associated with a small but significant reduction in number of teeth with periodontal bone loss.
Review of several studies. coffee consumption may or may not be associated with reduction in bone mineral density. Conflicting studies.
tooth pain better with ice cold water, worsens as soon it warms.
pains in bones of leg and long bones
slight draft or air increases pain in extremity
caries of bones
• teeth decay
• black and yellow teeth
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morning asthma
oppression of chest or tightness in chest or trachea constriction
must move, restlessness in asthma, wants to move continuously
asthma from emotional excitementwith anxious respiration
hysterical or gasping respiration
Coffee may protect against cirrhosis, especially alcoholic cirrhosis — people who drink 4 or more cups per day have up to an 80% lower risk in epidemiological studies .
Prostration of mind from alcoholic drinks
Alcoholic drinks agg stomach
Atrophy of liver
Burning pain in liver
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Coffee promotes GERD but is not associated with dyspepsia.
Coffee stimulates gallbladder contraction by increasing CCK
Coffee may or may not slow gastric emptying and small bowel transit.
Coffee promotes GERD but is not associated with dyspepsia.
Coffee stimulates gallbladder contraction by increasing CCK
Coffee may or may not slow gastric emptying and small bowel transit.
increased or decreased appetite for food or drink
stomach pain in epigastric region (burning or cramping) with nausea and vomiting, disgust for food, vomiting of mucous
stomach feels overloaded, clothing feels oppressive,
violent burping of sour taste
Coffee increased colorectal activity in some studies.
• diarrhea or loose, more frequent stool
• diarrhea from worry or sudden joy
constipation (less common) with hemorrhoids
Diarrhea from cholera and diarrhea from unexpected news
Extremely violet colic, excessive pain with anxiety with loud crying
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Epidemiological studies. coffee intake was associated with lower rosacea risk. Participants who drank over 4 cups per day were less likely to develop rosacea.
Case reports of allergic reactions to coffee include: skin rashes, such as hives or blotches of red skin.
Epidemiological studies. coffee intake was associated with lower rosacea risk. Participants who drank over 4 cups per day were less likely to develop rosacea.
Case reports of allergic reactions to coffee include: skin rashes, such as hives or blotches of red skin.
urticarial‐like eruptions with itching
itching skin during menses
rash from excitement
draft of air, increases painful erysipelas in extremities.
• Quick as lightening excitement or desire from moderate exciting causes (premature ejaculation)
• Excitation of the genitals to complete ecstasy becomes the work of a few seconds
• Ejaculation of semen is almost uncontrolled
• Desire is 10‐15 seconds too soon in both sexes
• Nocturnal emissions of semen followed by irritability
• Nightly involuntary emissions with frequent erections
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Coition painful at climax
Heavy menses with large black clots with restlessness from pain
Too frequent, protracted, heavy menses in nervous women with bright red face
Increased sexual desire during menses
• ineffectual labor with irregular contractionswith extreme fear of death, with great excitement of nervous system, any noise aggravates the labor pains
• cries out, sees vision and hears noises not there.
fear of death with labor pain
• labor pain worse after good news
lactation disappears from excitement in nervous person
• puerperal convulsions with extreme excitability
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Heart: Palpitations from sudden emotions, weak feeling in heart ,
Circulation: febrile warmth, plethora, fainting
Muscles: Mobility of muscles increased
Sexual: desire excited
Female: heavy black menstrual bleeding, metrorrhagia, hemorrhage
Labor: excessive labor pain contractions
Nervous system: neuralgia, increased pain, anxiety, fear of death, seizures
GI: increased stool, increased gastric acid secretion
Skin: various rashes, hives, measles‐like rash
Etc…
Sudden emotions causes various ailments
(HA, palpitations, asthma, suppressed lactation..) in a coffee state
Restless, anxious state, racing thoughts, fear of death, anguish with neuralgia
Worse heat of sun and in a coffee state
(palpitations, headaches)
Sensitivity to pain, esp of nerves, worse draft of air
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• Facial neuralgias, sciatica
• Seizures
• Asthma
• Colic
• Diarrhea from excitement,
• Ecstasy, excitement,
• Migraine headache,
• Palpitation or hypersensitivity of the heart
• Ill effects of overjoy
• Labor pains
• Heavy menstrual bleeding,
• Shock with anxiety and restlessness
• Insomnia
• Toothache
• Impotence
Take a homeopathic case
Use coffee as medicine if it mimics the
CONSTITUTIONAL
tendencies of the person and pattern of disease
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Cups of coffee.
Test blood sugar with and without coffee.
Have patient note how they feel on coffee. Each person reacts differently to coffee. Remember coffee really is a medicine. Drink in moderation.
Filter coffee using paper filter, if worry about elevated cholesterol to remove diterpenes from coffee.
No consensus on coffee in conventional literature
As Family Physicians, we need more tools and choices to improve the comfort of our patients.
Learn more at American Institute for Homeopathy
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Dr. Jane Li‐Conrad D.O.
Tel 440‐334‐6200
www.remedyjane.com
Marijuana State
Exalted spirit
Clairvoyance
Absent minded
Hypersensitivity of senses
Increased appetite
Dry mouth and lips
Etc..
Coffee State
Excited state
Anxious
Mental clarity
Hypersensitivity of senses
Jittery
Palpitations
Etc…
Salt State
Weakness
Confusion
Dullness
Edema extremities
Thirst
Dry mouth and lips
Hypertension
Etc..