Alternative Techniques for Determining Myosin Density in a Standard Actin Myosin Motility Assay
Lesson Plan: Muscular System 1...Myofilaments Thick and thin protein strands within each sarcomere....
Transcript of Lesson Plan: Muscular System 1...Myofilaments Thick and thin protein strands within each sarcomere....
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Lesson Plan: Muscular System 1
5 minutes: Breath of Arrival and Attendance
10 minutes: Gluteus Maximus and Gluteus Medius
40 minutes: Muscular System 1
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Lesson Plan: Muscular System 2
5 minutes: Breath of Arrival and Attendance
10 minutes: Sartorius and Tensor Fascia Latae
40 minutes: Muscular System 2
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Lesson Plan: Muscular System 3
5 minutes: Breath of Arrival and Attendance
50 minutes: Muscular System 3
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Classroom Rules
Punctuality- everybody's time is precious:
Be ready to learn by 9:00, we'll have you out of here by 1:30
Tardiness: arriving late, late return after breaks, leaving early
The following are not allowed:
Bare feet
Side talking
Lying down
Inappropriate clothing
Food or drink except water
Phones in classrooms, clinic or bathrooms
You will receive one verbal warning, then you'll have to leave the room.
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Gluteus Maximus and Gluteus Medius
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Gluteus Maximus
Origin: Posterior iliac crest Posterior sacrum and coccyx
Insertion: Gluteal tuberosity of femur IT tract
Actions: Extend the hip Abduct the hip Adduct the hip Laterally rotate the hip
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Gluteus Medius
Origin: Upper posterior ilium
Insertion: Greater trochanter of femur
Actions: Abduct the hip Flex the hip Extend the hip Medially rotate the hip Laterally rotate the hip
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Gluteus Maximus and Gluteus Medius
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TFL and Sartorius
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Sartorius
Origin: Anterior superior iliac spine (ASIS)
Insertion: Medial proximal tibia (pes anserinus)
Actions: Flex the hip Abduct the hip Flex the knee
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Tensor Fascia Latae (TFL)
Origin: Iliac crest posterior to ASIS
Insertion: IT tract
Actions: Abduct the hip Flex the hip Medially rotate the hip
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TFL and Sartorius
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“If there is one door in the castle you have been told not to go through, you must. Otherwise you’ll just be
rearranging furniture in rooms you’ve already been.”
-Anne Lamott
Muscular System 1
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What are some visible signs of the muscular system at work?
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What are some visible signs of the muscular system at work?
Rise and fall of the chest during breathing.
The feel of your heart beating.
Facial expressions communicating how we feel.
Locomotion to get us from here to there.
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Skeletal muscles . Related fascial structures including tendons and aponeuroses.
Anatomy
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Movement Posture maintenance Moving substances Heat production
Physiology
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Physiology
Movement Skeletal muscle contractions produce movement of the body as a whole (locomotion) and movement of its parts.
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Physiology
Posture maintenance Skeletal muscles must contract to maintain static postures, such as in sitting and standing .
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Physiology
Posture maintenance Skeletal muscles must contract to maintain static postures, such as in sitting and standing .
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Physiology
Moving substances Contraction of skeletal muscles promotes lymphatic flow and blood flow from the extremities to the heart .
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Physiology
Moving substances Contraction of skeletal muscles promotes lymphatic flow and blood flow from the extremities to the heart .
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Physiology
Heat production Muscle contractions produce and release heat that is important for homeostasis. AKA: thermogenesis .
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myofilaments → sacromere → myofibril → muscle fiber (cell) → fascicle → skeletal muscle (organ)
Myofilaments Sacromere Myofibrils Muscle fiber Fasciculi
Organization: Muscle Cells into Muscle Organs
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Organization: Muscle Cells into Muscle Organs
Myofilaments Thick and thin protein strands within each sarcomere. Consist of actin and myosin.
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Organization: Muscle Cells into Muscle Organs
Sarcomere A muscle's contractile unit. Found within myofibrils.
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Organization: Muscle Cells into Muscle Organs
Sarcomere A muscle's contractile unit. Found within myofibrils.
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Organization: Muscle Cells into Muscle Organs
Myofibrils Thin strands within each muscle fiber. Contain myofilaments.
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Organization: Muscle Cells into Muscle Organs
Muscle fiber Thread-like muscle cell.
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Organization: Muscle Cells into Muscle Organs
Fasciculi Groups of muscle fibers or neurons. Singular is fascicle.
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Organization: Muscle Cells into Muscle Organs
NOTE: In the muscular system fasciculi are groups of muscle fibers, but in the nervous system fasciculi are groups of neurons.
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Endomysium Perimysium Epimysium Deep fascia
Myofascial Tendon Tendon sheath Aponeurosis Retinacula
Connective Tissues
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Endomysium, Perimysium, Epimysium, Deep Fascia
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Connective Tissues
Endomysium Connective tissue layer that surrounds individual muscle fibers .
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Connective Tissues
Perimysium Connective tissue layer that surrounds fasciculi .
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Connective Tissues
Epimysium Connective tissue layer surrounding an entire muscle .
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Connective Tissues
Deep fascia Connective tissue layer that surrounds muscle groups .
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Superficial Fascia
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Connective Tissues
Myofascial Referring to skeletal muscles and related fascia in the muscular system.
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Connective Tissues
Tendon Cord-like structure anchoring the end of a muscle to a bone.
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Connective Tissues
Tendon sheath (AKA: synovial sheath) Tube-like structure lined with synovial membrane that surround long tendons.
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Connective Tissues
Aponeurosis (p. aponeuroses) Broad, flat tendon. Attaches skeletal muscle to bone, another muscle, or skin.
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Connective Tissues
Retinacula (s. retinaculum) Bandage -like retaining bands of connective tissue found primarily around the elbows, knees, ankles, and wrists. May also act as a pulley for tendons.
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Sarcoplasm Sarcolemma Sarcoplasmic reticulum T-tubules Sarcomere
Muscle Cells
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Connective Tissues
Sarcoplasm Muscle cell cytoplasm . Sarcolemma Muscle cell membrane .
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Connective Tissues
Sarcoplasm Muscle cell cytoplasm . Sarcolemma Muscle cell membrane .
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Connective Tissues
Sarcoplasmic reticulum A fluid-filled system of sacs similar to endoplasmic reticulum. Stores and releases calcium ions.
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Connective Tissues
T-tubule Runs transversely across the sarcoplasmic reticulum, forming inward channels. Transports stored calcium ions from the sarcoplasmic reticulum into the interior of the muscle cell.
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Connective Tissues
Sarcomere A muscle's contractile unit. Found within myofibrils.
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Thin myofilaments Actin Tropomyosin Troponin
Thick myofilaments Myosin
Myofilaments
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Myofilaments
Thin myofilaments Actin Protein molecules within a muscle cell that contain binding sites
used during skeletal muscle contraction; help make up thin myofilaments.
Tropomyosin Protein molecules. Troponin Protein molecules.
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Myofilaments
Thick myofilaments Myosin Protein molecules within a muscle cell that attach to actin during
skeletal muscle contraction. Make up the bulk of thick myofilaments.
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Muscle Cell Properties
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Muscle Cell Properties
Excitability The ability to respond to a stimulus .
Contractility The ability to shorten .
Extensibility The ability to lengthen .
Elasticity The ability to return to its original shape after movement.
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Mechanism of Contraction
“Sliding Filament Mechanism”
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Mechanism of Contraction “Sliding Filament Mechanism”
Nerve impulse An electrical signal that conveys information along a neuron.
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Mechanism of Contraction “Sliding Filament Mechanism”
Motor neuron Neuron that sends a nerve impulse to a muscle cell.
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Mechanism of Contraction “Sliding Filament Mechanism”
Motor unit Single motor neuron plus all the muscle fibers it innervates.
Note: one motor neuron can innervate 2 to 2000 muscle fibers.
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Mechanism of Contraction “Sliding Filament Mechanism”
Motor end plate Folded sections of the sarcolemma where motor neurons attach.
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Mechanism of Contraction “Sliding Filament Mechanism”
Neuromuscular junction Junction between a motor neuron and a motor end plate.
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Mechanism of Contraction “Sliding Filament Mechanism”
Synaptic cleft (AKA: synaptic gap) Space between the end of a motor neuron and another neuron, a muscle cell, or a gland.
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Mechanism of Contraction “Sliding Filament Mechanism”
Acetylcholine Neurotransmitter that crosses the synaptic cleft.
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Mechanism of Contraction “Sliding Filament Mechanism”
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Mechanism of Contraction “Sliding Filament Mechanism”
Non-Contracting State: “Two protein molecules, troponin and tropomyosin, are
positioned on thin myofilaments to block myosin binding sites. Without these regulatory
proteins, muscles would be in a constant state of contraction.”
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Mechanism of Contraction “Sliding Filament Mechanism”
Excitation of the Sarcolemma: “The contraction of a skeletal muscle begins with
a nerve impulse sent from the central nervous system through a motor unit (messages of
inhibition are sent by different neurons and this will be covered in Somatic Nervous
system). When the nerve impulse reaches the neuromuscular junction, acetylcholine is
released into the synaptic cleft. It crosses the gap and binds with receptor sites on the
motor end plate. From there an impulse is sent through the t-tubules into the sarcomeres
triggering the release of calcium ions from the sarcoplasmic reticulum.”
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Mechanism of Contraction “Sliding Filament Mechanism”
Excitation of the Sarcolemma
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Mechanism of Contraction “Sliding Filament Mechanism”
Cross-Bridging: “Now that calcium is present in the sarcomere, it binds to
troponin causing tropomyosin to slide off and expose the site allowing myosin heads to
bind to thin myofilaments.”
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Mechanism of Contraction “Sliding Filament Mechanism”
Power Stroke: “Myosin heads, which are hinged at their base, then toggle in a
mechanism similar to a light switch. This action causes thin myofilaments to slide
toward the center of the sarcomere which shortens the overall length of the muscle fiber.
Yeah! We have contraction!”
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Mechanism of Contraction “Sliding Filament Mechanism”
All or None Response: “When a motor neuron delivers a stimulus of
contraction, all the muscle fibers of the motor unit receive the same signal at the same
time. IF the stimulus is sufficient, THEN all muscle fibers associated with the motor unit
will contract to its fullest extent; there is no partial contraction. Conversely, IF the
stimulus is below the required threshold, THEN muscle contraction will not occur and
the muscle fiber will remain at full resting length.”
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Mechanism of Contraction “Sliding Filament Mechanism”
Recruitment: “Numerous motor units are linked to a single skeletal muscle. The
nervous system regulates the amount of muscular contraction by activating only the
motor units needed to perform a given action. IF more strength is required, THEN
additional motor units are recruited resulting in a stronger muscle contraction.”
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Mechanism of Contraction “Sliding Filament Mechanism”
Relaxation: “Almost immediately after the sarcoplasmic reticulum releases
calcium ions into the sarcomeres, it begins to actively pump them back into its sacs.
Freed from its chemical bond with the calcium ions, the tropomyosin slides back to
cover the myosin binding sites on thin myofilaments. This action releases the myosin
heads and returns them to their pre-contraction resting state. The muscle is now at rest.”
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Energy Sources for Contraction
Adenosine triphosphate Fuel Oxygen
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Energy Sources for Contraction
Adenosine triphosphate (AKA: ATP) The body's energy storage molecule.
Fuel Glucose, fat, or, rarely, protein; used to form ATP in the mitochondria. By- products are CO2 and water (from aerobic metabolism), or, from the initial anaerobic process (which only uses carbohydrate, and not O2), lactic acid.
Oxygen Combined with fuel in the mitochondria during aerobic metabolism, yielding energy (for making ATP) plus CO2 plus H2O.
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Types of Skeletal Muscle Fibers
Slow twitch Fast twitch Intermediate twitch
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Types of Skeletal Muscle Fibers
Slow twitch Skeletal muscle fibers that contract slowly and are fatigue resistant . AKA: red muscle. Examples: postural muscle, core muscle, legs of long distance runners.
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Types of Skeletal Muscle Fibers
Fast twitch Skeletal muscle fibers that contract forcefully and fatigue rapidly. AKA: white muscle. Examples: arm muscles.
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Types of Skeletal Muscle Fibers
Intermediate twitch Skeletal muscle fibers that are more fatigue resistant than fast twitch, and more forceful than slow twitch. AKA: pink muscle. Examples: legs of world class sprinters and arms of world class boxers.
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Parts of a Skeletal Muscle
Belly Origin Insertion
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Parts of a Skeletal Muscle
Belly The wide central portion of a skeletal muscle that contains the sarcomeres.
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Parts of a Skeletal Muscle
Origin Tendinous muscle attachment on the less movable bone or other structure. Typically medial or proximal to the insertion.
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Parts of a Skeletal Muscle
Insertion Tendinous muscle attachment on the more movable bone or structure. Typically lateral or distal to the origin.
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Parts of a Skeletal Muscle
Functional reversibility Property of some muscles that reverse the roles of the origins and insertions. Examples: iliopsoas during hip flexion.
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Parts of a Skeletal Muscle
Uniarticular Crosses one joint. Biarticular Crosses two joints and acts on both joints. Multiarticular Crosses more than two joints and acts on all joints.
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Muscles Actions
Prime mover Antagonist Synergist Fixator
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Muscle Actions
Prime mover Muscle responsible for causing a specific or desired action. AKA: agonist. Example: biceps brachii during elbow flexion.
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Muscle Actions
Anatagonist Muscles that must relax and lengthen or eccentrically contract and lengthen to allow actions of the prime mover to occur. Example: triceps brachii during elbow flexion.
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Muscle Actions
Synergist Muscle that aids movement by contracting at the same time as the
prime movers. Example: pronator teres during elbow flexion with the forearm pronated.
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Muscle Actions
Fixator Specialized synergist muscles that act as a stabilizer . Example: deltoid during elbow flexion.
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Types of Muscle Contractions
Isotonic contraction Concentric contraction Eccentric contraction
Isometric contraction
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Types of Muscle Contractions
Isotonic contraction Contraction in which muscle changes length . Concentric contraction Type of isotonic contraction where the muscle shortens . Eccentric contraction Type of isotonic contraction where the muscle lengthens .
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Types of Muscle Contractions
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Types of Muscle Contractions
Isometric contraction Contraction in which muscle length remains the same.
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Stretching and Stretch Receptors
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Stretching and Stretch Receptors
Stretching Method that lengthens/elongates soft tissues.
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Stretching and Stretch Receptors
Hyperflexibility Flexibility beyond a joint's normal range of motion. Contributes to joint instability. AKA: hypermobility.
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Stretching and Stretch Receptors
Muscle spindle Stretch receptor located within the muscle belly . Detects sudden stretching, causing the nervous system to respond by reflexively contracting the muscle.
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Stretching and Stretch Receptors
Golgi tendon organ Receptor located at the musculotendinous junction. Detects tension and excessive stretch, causing the nervous system to respond by inhibiting contraction.
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Posture and Muscle Tone
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Posture and Muscle Tone
Posture How the body distributes itself in relation to gravity over a base or bases of support.
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Posture and Muscle Tone
Good posture Keeping the body's center of gravity over its base. This helps to avoid unnecessary soreness and fatigue by reducing strain on muscles, ligaments, and bones.
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Posture and Muscle Tone
Muscle tone Continued partial contraction of skeletal muscle. AKA: tonus.
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Posture and Muscle Tone
Flaccid Skeletal muscle with less tone than normal. First stage of muscle atrophy.
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Posture and Muscle Tone
Spastic Skeletal muscle with more than normal tone.
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Effects of Massage Therapy on the Muscular System
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Effects of Massage Therapy on the Muscular System
“Decrease tension within the muscle-tendon unit.”
By increasing circulation to muscles and block nerve impulses.
This may allow muscle to elongate.
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Effects of Massage Therapy on the Muscular System
“Assist in the treatment of tendonitis.”
Reducing inflammation with circulatory work.
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Effects of Massage Therapy on the Muscular System
“Increase scar tissue strength to aid in tendon healing.”
Deep cross fiber friction can reweave and remodel the scar tissue so that the fibers are parallel to each other.
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Effects of Massage Therapy on the Muscular System
“Increase range of motion (ROM).”
The mechanism of action is not clear, but may be due to: Decreased pain or stiffness Decreased muscle tightness Increased muscle length
Increased ROM is an important treatment goal.
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Effects of Massage Therapy on the Muscular System
“Decrease delayed onset muscle soreness (DOMS).”
Due to flushing out of toxins through circulatory work.
Studies have produced contradictory results.
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Effects of Massage Therapy on the Muscular System
“Decrease electromyography (EMG) activity, suggesting increased muscle relaxation and decreased muscle fatigue.”
A fatigued muscle recruits additional motor units to complete the task resulting in increased electrical activity.
A lower EMG signal can represent a more efficient muscular contraction.
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Effects of Massage Therapy on the Muscular System
“Decrease pain and may activate the parasympathetic nervous system, causing relaxation and reduction of trigger point activity.”
This can be accomplished through trigger point work.
Trigger point Localized areas of hyperirritability. When pressed, may refer sensations (usually pain) to other areas of the body.
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Effects of Massage Therapy on the Muscular System
“Reduce chronic tension headaches.”
Using trigger point work.
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Effects of Massage Therapy on the Muscular System
“Reduce lower back pain.”
Using trigger point work.
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Effects of Massage Therapy on the Muscular System
“Reduce pain and other symptoms of fibromyalgia.”
Although many clients request deep pressure, this often provokes strong reactions for several days following treatment.
A very slow increment in depth of massage strokes, from session to session, with careful deactivation of tender areas is recommended.
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“If there is one door in the castle you have been told not to go through, you must. Otherwise you’ll just be
rearranging furniture in rooms you’ve already been.”
-Anne Lamott
Muscular System 3
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“If there is one door in the castle you have been told not to go through, you must. Otherwise you’ll just be
rearranging furniture in rooms you’ve already been.”
-Anne Lamott
Muscular System 1