Lec21 Enzymes
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Transcript of Lec21 Enzymes
EnzymesBiology 3 Kawashima
What is a catalyst?
An agent that speeds up a chemical reaction without being consumed by
the reaction.
What is an enzyme?
A catalytic protein that speeds up the construction (anabolism) or
breakdown (catabolism) of molecules
ΔG = -7 kcal/mol
Activation Energy
Energy required for the reaction to proceed.
This energy investment is used to “contort” the reactants into its
transition state
How enzymes lower the energy barrier
• Provides template for proper orientation of substrates for the reactionTemplate
• Alters conformation of substrate towards its transition stateContort
• Provides a more conducive environment (pH) for reaction
Microenvironment
• Active site may bond with substrate to form an intermediate Participate
Each type of enzyme has a specific set of optimum conditions