Layne Johnson "e-Science at the Univeristy of Minnesota"
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Transcript of Layne Johnson "e-Science at the Univeristy of Minnesota"
©2012 Regents of the University of Minnesota. All rights reserved.
e-Science at the University of Minnesota
e-Science Symposium National Network of Libraries of Medicine
South Central Region Texas Medical Center Library
Layne M. Johnson, Ph.D. February 13, 2012
©2012 Regents of the University of Minnesota. All rights reserved.
History, Evolution & Current State
• Present my experiences as a researcher and show how changes in research call for the expertise of librarians and information specialists
• Review the experiences at Minnesota and the roles that the University Library colleagues have played
• Take a fresh look at the developing requirements and advances in e-science to best prepare ourselves and researchers to meet future needs
©2012 Regents of the University of Minnesota. All rights reserved.
First, Let’s Agree…
• E-Science (or eScience) is computationally intensive scientific research, typically performed over distributed networks and involving large amounts of data. Also, e-science often involves collaboration.
• E-Science can be referred to as E-Research to accommodate disciplines outside of the sciences, e.g. the Digital Humanities.
©2012 Regents of the University of Minnesota. All rights reserved.
E-Science
• …has often been called cyberinfrastructure in the U.S.
• Nowadays, cyberinfrastructure is used less (at least by me), and e-Science is used more frequently.
©2012 Regents of the University of Minnesota. All rights reserved.
Technology is the Major Impact on Science
• High-throughput screening, sequencing
• Equipment generating data 24/7
• Information increasing logarithmically
• Communications, networking
• Regulations, standards
©2012 Regents of the University of Minnesota. All rights reserved.
Layne, the Bacteriologist
©2012 Regents of the University of Minnesota. All rights reserved.
Screening for New Medicines
Single colony
24 96 384
384 colonies
What next?
©2012 Regents of the University of Minnesota. All rights reserved.
Technology Increased Speed & Data Generation
©2012 Regents of the University of Minnesota. All rights reserved.
Manual Colony Selection Became Automated
Aseptic Robotic Automation
mRNA Microarrays [increased
#samples, increased sensitivity]
©2012 Regents of the University of Minnesota. All rights reserved.
More Data Requires (More) Computers
0
50000
100000
150000
200000
250000
300000
350000
400000
450000
500000
1 Colony 24 Colonies 96 Colonies 384 Colonies
240 28800
115200
460800
Bacterial Colonies Tested
# o
f data
po
ints
ge
ne
rate
d
©2012 Regents of the University of Minnesota. All rights reserved.
Researchers & Computers Network to Manage Data – Share, Store, Analyze
©2012 Regents of the University of Minnesota. All rights reserved.
Reviewing our definition…
…computationally intensive scientific research, typically performed over distributed networks
and involving large amounts of data, with a dash of collaboration thrown in
©2012 Regents of the University of Minnesota. All rights reserved.
Which Leads to the Next Part of the Story
©2012 Regents of the University of Minnesota. All rights reserved.
Layne, the University of Minnesota Person / Gopher / Frozen Guy
aka informationist, informaticist, librarian, etc.
©2012 Regents of the University of Minnesota. All rights reserved.
Research at University of Minnesota
• Twin Cities Campus
– >52,000 students, 3400 faculty, 150 graduate and professional degrees
– Medicine to business, law to liberal arts, science and engineering to architecture and agriculture
– ~$770M in sponsored research in 2011, $305M from NIH
– 2010 NSF research ranking – 8th among top 20 public research universities in the US
©2012 Regents of the University of Minnesota. All rights reserved.
Academic Health Center (AHC)
©2012 Regents of the University of Minnesota. All rights reserved.
E-Science Landscape – 2006 - Present
• Libraries developed a model for assessing research support – 2005-2006 – humanities, social sciences
• 2006-2007 – analysis of science faculty and graduate students re: discovery, use, & management of data and information
• 2007 – ARL report – “Agenda for Developing E-Science in Research Libraries” – W. Lougee coauthor
©2012 Regents of the University of Minnesota. All rights reserved.
E-Science Landscape – 2006 - Present
• 2007+ - virtual community development – EthicShare, AgEcon
• 2007-2009 – Cyberinfrastructure Alliance – University Libraries, IT, Office VP Research
• 2010 – data audits, Research Networking implemented
• 2010+ - Data Management workshops - >300 faculty
©2012 Regents of the University of Minnesota. All rights reserved.
Things We’ve Learned from Researchers
• Participants want
– help with Data Management Plans (80%)
– to share data with collaborators (84%)
– to use metadata services (70%)
– auto-backup data services (77%)
– long term access to data (76%)
– repositories for data on campus (e.g. GIS, 70%)
©2012 Regents of the University of Minnesota. All rights reserved.
Researchers also indicate they’d like:
• to gain a better understanding of new data management and collaboration tools (76%)
• to be able to not only identify experts, but also core resources, like biorepository samples, core centers of technology and methods & equipment support
• to compete more aggressively for funding opportunities
©2012 Regents of the University of Minnesota. All rights reserved.
We used Charles Humphrey’s model of the Research Life Cycle to help inform or
strategic direction for supporting e-science at the University of Minnesota
(in the spirit of full disclosure, we modified the model – and so should you)
©2012 Regents of the University of Minnesota. All rights reserved.
The Research Life Cycle
©2012 Regents of the University of Minnesota. All rights reserved.
We Identified Library Roles
• Content/Collection Development & Managing Datasets
• Teaching and Learning
• Outreach
• Liaison Services
• Translational Science and Informatics Support
• Research Networking
• Leadership
©2012 Regents of the University of Minnesota. All rights reserved.
Research Networking
• We first implemented open source Harvard Profiles (UMN Profiles) - ~4,000 researchers
• Collaboration with Office VP Research, Libraries, Colleges – we are implementing SciVal Experts, Funding, Spotlight
– Got us at the table
– Is pushing us into ontology work, linked open data, and the semantic web
©2012 Regents of the University of Minnesota. All rights reserved.
Data Management Plans (DMP)
• Brief description of how primary
investigator will comply with funder’s data
sharing policy
• Largest funding agencies include NIH and NSF
©2012 Regents of the University of Minnesota. All rights reserved.
Several DMP Tools Are Available
• A variety of data management resources have been developed at by the University Libraries the University of Minnesota. Check into them at http://www.lib.umn.edu/datamanagement
• For DMPs, see specifically:
http://www.lib.umn.edu/datamanagement/DMP (take a look at the DMP checklist)
©2012 Regents of the University of Minnesota. All rights reserved.
DataOne (NSF) DMPs
• Several examples are provided at: http://www.dataone.org/plans
• DMPTool provides guidance and resources for your data management plan
– Create plans
– Meet funder requirements
– Step by step instructions
– Get data management advice
©2012 Regents of the University of Minnesota. All rights reserved.
Where Our Work is Leading Us
• We realize that there are gaps in understanding privacy and security issues around data – especially in the health sciences
• We also have identified gaps in our understanding of bench scientist (discovery, T1, pre-human) needs
• We recognize an opportunity to transform several roles to support research and data needs
©2012 Regents of the University of Minnesota. All rights reserved.
Research Support and Services Collaboratives
• Data Access Working Group
• Research Communities and Networks
• Digital Humanities
• We see the boundaries between the Academic Health Center dissolving and a focus on enterprise solutions expanding
• One example is the AHC Information Exchange
©2012 Regents of the University of Minnesota. All rights reserved.
AHC Information Exchange
• Governance structure consisting of the SVP AHC, SVP of Research, CTSA PI
• Working groups include informatics, research studies, architecture
– Many groups request support from the libraries
– Identity (like ORCID, etc.)
– Metadata
– Classification
©2012 Regents of the University of Minnesota. All rights reserved.
©2012 Regents of the University of Minnesota. All rights reserved.
Future of e-science
• A positive development for libraries – it is important for us to take the lead
– This is shown to be true from e-Science Institute activities with ARL
• Need for open dialogue at all levels – local, regional, national, global
• Opportunities abound – and can be leveraged with existing resources and sound strategies
©2012 Regents of the University of Minnesota. All rights reserved.
Acknowledgements
• University of Minnesota Health Sciences Colleagues, particularly Andre Nault, Jonathan Koffel, Linda Watson
• University Library colleagues, especially Lisa Johnston, John Butler, Meghan Lafferty, Wendy Lougee
• Health Informatics Colleagues and Clinical and Translational Science Institute Colleagues
• Cooper Mark Edward Johnson