K.V. CHALAM, MD, PhD, MBA, FACS.content.stockpr.com/.../K.V.Chalam_MD_PhD_MBA_FACS_CV.pdf ·...

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K.V. CHALAM, MD, PhD, MBA, FACS. Curriculum vitae

INDEX Page No.

1. Biodata p2

2. Current Position p2-3

3. Academic Qualifications p4

4. Membership p7

5. Honors & Awards p8

6. Bibliography p15- 68

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K.V. CHALAM, MD, PhD, MBA, FACS Curriculum vitae

DATE OF BIRTH August 1, 1959

MARITAL STATUS Married

CITIZENSHIP United States

BUSINESS ADDRESS Department of Ophthalmology

580 W 8th Street

Jacksonville, FL 32209.

Tel No. 904-403-2607 / 244-9361

Fax No.904-244-9391

HOME ADDRESS 10053 Lakes End Court

Jacksonville, FL 32256.

Tel No. 904-403-2607 / 519-2949

Fax No.904- 519-2949

[email protected] ; [email protected]

PRESENT ACADEMIC POSITION 1. Chairman and Tenured Professor

Department of Ophthalmology

University of Florida College of Medicine

Jacksonville, Florida

2. Assistant Dean

Veterans Administration Affairs



3. Program Director

Residency Education

Fellowship Education




4. Chief, Ophthalmology Service

mailto:[email protected]

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Shands Jacksonville University Hospital



4. Director, Vitreoretinal Service

Neuroophthalmology service

Electrophysiology Service

Uveitis and Ocular Oncology Service


University of Florida College of Medicine, Jacksonville, Florida

PREVIOUS POSITION 1. Associate Chairman and Associate Professor




2. Residency Program Director

Residency education


USC School of Medicine

Columbia. South Carolina

2. Associate Professor


USC School of Medicine


3. Attending ophthalmologist

Richland Memorial Hospital

Dorn Jennings Veterans Administration Hospital

Health South Hospital

Providence Hospital


4. Director, Vitreoretinal Service

Neuroophthalmology service

Electrophysiology Service


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USC School of Medicine,


ACADEMIC APPOINTMENTS / POSITIONS:

2006-Present Tenured Professor and Chairman



2004-Present Basic Science Research Professor

Department of Microbiology and Pathology

USC School of Medicine, Columbia, South Carolina

2000-2005 Associate Professor and Associate Chairman



1998-99 Associate Professor


USC School of Medicine. Columbia, South Carolina

1994-98 Assistant Professor


USC School of Medicine. Columbia, South Carolina

1997-Prsesnt Visiting Lecturer


Harvard Medical School, Boston, Massachusetts

1993-94 Instructor


UT Southwestern Medical School. Dallas, Texas

1992-93 Assistant Instructor


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UT Southwestern Medical School. Dallas, Texas

POSTGRADUATE QUALIFICATIONS:

Earned

ABO Certification Diplomat, American Board of Ophthalmology

Nov.93/ Recertified Nov.2003

Ph. D (Molecular Biology) University of South Carolina

Visual Science, Biomedical Sciences Graduate Program

Columbia, South Carolina. May.O4 / 3.63 / 4.00 GPA

M.B.A Webster University

St.Louis, Missouri. Oct. 99 / 3.90 / 4.00 GPA

F.R.C.S.C (Ophthalmology) Fellow, Royal College of Physicians and Surgeons

CANADA. Nov. 90

F.R.C. Ophth. Fellow, Royal College of Ophthalmologists

London, ENGLAND. Nov. 90.

F.R.C.S (Ophthalmology) Fellow, Royal College of Surgeons of Edinburgh. ENGLAND.

Nov.84.

D.O.R.C.S (Ophthalmology) Diplomat, Royal College of Surgeons

IRELAND. Oct. 84.

M.S. (Ophthalmology) Post Graduate Institute of Medical Education and Research, Chandigarh

INDIA. Jan.83

Admitted

F.A.C.S Fellow, American College of Surgeons

Ophthalmology, 1996

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F.I.C.S Fellow, International College of Surgeons

USA Section, 1996

GRADUATE EDUCATION:

M.D. University of State of New York

Albany, New York. June 92

M.B.B.S Guntur Medical School

Guntur, INDIA. Oct. 72- Oct. 78.

I.S. Andhra Loyola College

Vijayawada. India. July 70-June 72

POSTGRADUATE CLINICAL TRAINING:

FELLOWSHIP:

Vitreo-retinal Surgery UT Southwestern Medical School, Dallas


July 92 -June 94.

Chairman: Dr. J. McCulley.

Preceptor. Dr. R. Anand / Dr. C. Wilson.

Neuroophthalmology UT Medical School at Houston


July 87 - June 88.

Chairman: Dr. R. Ruiz.

Preceptor: Dr. R. Tang.

Ocular Oncology MD Anderson Cancer Center, Houston

Department of Ophthalmology / Head and Neck Surgery

July 87 - June 88.

Chairman: Dr. H.Goepffert.

Preceptor: Dr. R. Tang

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RESIDENCY & INTERNSHIP:

Ophthalmology Catholic Medical Center

(Residency) Affiliate. Cornell University Medical School

New York. July 89- June 92.

Chairman: Dr. David Paton

General Surgery Catholic Medical Center

(Internship) Affiliate. Cornell University Medical School

New York. July 88- June 89.

Chairman: Dr. Walter Pizzi

Instructor Department of Ophthalmology

Ipswich Hospital, Ipswich, ENGLAND

May 85- June 87

Chairman: Dr. M. J. Parkinson

Senior Resident Prince Charles Eye Unit.

Ophthalmology King Edward VII Hospital, Windsor. ENGLAND.

March 84 - April 85

Chairman: Dr. J.J. Kanski.

Teaching fellow Post Graduate Medical Institute

Ophthalmology Chandigarh, INDIA.

Jan. 80 - March 83.

INTERNSHIP Guntur General Hospital. Guntur, India.

Transitional Oct.78-Dec. 79

LICENSURE:

South Carolina July 94/ 17105

Florida Jan.97/ 72613

New York Jan. 89/ 176948

Texas July.92 / J-1634

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ECFMG Jan 79/ 307-821-9

USLME Sept. 83/ 307-821-9

FLEX Dec. 86/ I.D. NO. 550801024

Eligible for licensure in all states

United Kingdom April 84/ 121346

NATIONAL AND INTERNATIONAL SPECIALTY BOARD CERTIFICATION:

Diplomat, American Board of Ophthalmology, November.1993. Recertified 2003

Royal college of Physicians and Surgeons of Canada, November.1990

Royal College of Ophthalmologists, United Kingdom, July.1990

Royal College of Surgeons, Edinburgh, United Kingdom, November.1984

Royal college of Physicians and Surgeons, Ireland, August.1984

Certificate in specialist surgical training, Royal Academy of Medicine, London, January.1998

MEMBERSHIP, PROFESSIONAL SOCIETIES AND LEARNED SCIENTIFIC BODIES:

Fellow / American College of Surgeons (FACS)

Fellow / American Academy of Ophthalmology

Fellow / Association for Research and Vision in Ophthalmology

Member, American Society of Retinal Specialists

Member, American Association for Advancement of Science

Member, Association of Biomedical Engineers

Member, International Society for Stem Cell Research

Member/ Association of University Professors in Ophthalmology

Member/ American Association of University Professors

Member, Medical Group Management Association

Member, American Medical Association, Southern Medical Association

Member/Canadian Ophthalmological Society

Fellow/American Society of Cataract and Refractive Surgeons

Fellow, Royal College of Ophthalmologists, England

Fellow, Royal College of Surgeons, Canada

Fellow, Royal College Surgeons, Edinburgh

Member, Florida Ophthalmological Society

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Member, Florida Medical Association

Member, All India Ophthalmological society

Member, North American Neuro-ophthalmology Society

Member, Uveitis Society

Member, Ophthalmic Echographers Association

Member, Sigma XI Science Society

Member, American Medical Writers Association

Member, International Society for Ocular Pharmacology and Toxicology

HONORS & AWARDS:

“Deans Research / Scholar Award” for outstanding research and scholarly contributions during 2004-05 Academic Year

“Senior Achievement Award” for outstanding program service to American Academy of Ophthalmology. 2010

“Senior Honor Award” for outstanding program service to American Society of Retinal Specialists. 2005

“Director, Top Research Site award from National Institute of Health-Diabetic Retinopathy Clinical Research Network” for year 2008 (1/202 investigative sites)

Chair, Basic and Clinical Science Course Volume 2, American Academy of Ophthalmology, Continuing Medical Education Division, 2005-2010

Secretary-Treasurer, International Society of Ocular Toxicology and Pharmacology, 2005-2013

“Best Teacher of the year” academic years 1995 and 1996, Department of Ophthalmology, USC School of Medicine, Columbia, South Carolina.

“Achievement Honor Award” for outstanding program service to American Academy of Ophthalmology. 2000

“Honor Award” for outstanding program service to American Society of Retinal Specialists. 2004

“Member, Steering Committee” Diabetic retinopathy Clinical Research Network, National Eye Institute.

“Chancellor List” for outstanding graduate work at University of South Carolina, 2005

“Certificate of Appreciation” for outstanding program service to American Board of Ophthalmology. 1997 and 2007

“Certificate of Appreciation” for outstanding program service to National Eye Care Project of American academy of Ophthalmology. 2001

“Who is Who in World” Marquis Who‟s Who Publication 2000-Present

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“Who is Who in America” Marquis Who‟s Who Publication 2000- Present

Associate Examiner, American Board of Ophthalmology, 1995 – Present

“Who is Who in Science and Engineering” Marquis Who‟s Who Publication 2000- Present

“Who is Who in Finance and Industry” Marquis Who‟s Who Publication 2000- Present

“Who is Who in America” Strathmore‟s Who‟s Who Publication 2000-2001

“Who is Who in Science and Engineering” Strathmore‟s Who‟s Who Publication 2000-2001

“Who is Who in Science and Engineering” Lexington‟s Who‟s Who Publication 2000-2001

Score of 99 in written qualifying examination of American Board of Ophthalmology, 1993.

“2000 Outstanding Scholars of 21st Century” International Biographic Institute Publication 200-2001

OKAP Score of 99 for three consecutive years during residency training, 1989 - 92

Chief Resident, Catholic Medical Center, Department of Ophthalmology 1991 - 92

Annual Residents Day Research Award, Catholic Medical Center, 1990, 91 & 92

FIRST RANK in Master of Surgery (Ophthalmology) Examination, 1983, India

Honors and Distinction In ANATOMY 6/75

Honors and Distinction In PHYSIOLOGY 6/75

Honors and Distinction In BIOCHEMISTRY 6/75

Honors and Distinction In PHARMOCOLOGY 6/76

Honors and Distinction In PATHOLOGY 6/77

Honors and Distinction In MICROBIOLOGY 6/77

Honors and Distinction In PUBLIC HEALTH 12/77

Honors and Distinction In GENERAL MEDICINE 8/78

Honors and Distinction In GENERAL SURGERY 8/78

Class standing 1/152 in Medical School, 10/78

College Scholarships, Medical College, Guntur, 1972 - 78

National Science Talent Search Scholarship, National Council for Educational Research and Training, Govt. of India, 1970

National Scholarship, Ministry of Education and Youth Services, Government of India, 1970

Ranked first in the state Higher secondary examination, 1970

COMMITTEE APPOINTMENTS:

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2004-present Chairman, Basic and Clinical Science Course Review Committee, Continuing Medical Education Division, American Academy of Ophthalmology

2000-present Member, Online Continuing Medical Education Committee, American Academy of Ophthalmology

2000-present Program Director, Residency and Fellowship Education, Department of Ophthalmology, Shands Jacksonville Hospital, Jacksonville, Florida

2000-present Chief, Department of Ophthalmology, Shands Jacksonville Hospital, Jacksonville, Florida

2000-present Chief Compliance Officer, Department of Ophthalmology, Shands Jacksonville Hospital, Jacksonville, Florida

2000-present Member, University of Florida Finance Committee, Jacksonville, Florida

2004-present Member, Institutional Review Board, University of Florida College of Medicine, Jacksonville Campus, Florida

2000-present Member, Board of Directors, University of Florida Jacksonville Health Sciences Incorporated, Jacksonville, Florida

2000-present Member, Medical Executive Committee, Shands Jacksonville Hospital, Jacksonville, Florida

2000-present Member, Gradual Medical Education Committee, Shands Jacksonville Hospital, Jacksonville, Florida

2001-present Member, Ethics Committee, Shands Jacksonville Hospital, Jacksonville, Florida

2000-present Member, Telephone Task Force, Shands Jacksonville Hospital, Jacksonville, Florida

1995-2002 Member, Basic and Clinical Science Course Review Committee, Continuing Medical Education Division, American Academy of Ophthalmology

1994-2000 Member, Operating Room Committee, Richland Memorial Hospital, Columbia, South Carolina

1994-2000 Chair, Resident Selection Committee, Department of Ophthalmology, University of South Carolina School of Medicine

1994-2000 Member, Graduate Medical Education Committee, Richland Memorial Hospital

1994-2000 Member, Education Trust Committee, University of South Carolina School of Medicine

1994-2000 Member, Student Advisory Committee, University of South Carolina School of Medicine

1995-2000 Member, Quality Assurance Committee, Department of Ophthalmology, University of South Carolina School of Medicine

1995 Member, Internal Review Committee, Department of Anesthesia, Richland Memorial Hospital

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1995 Member, Internal Review Committee, Department of Emergency Medicine, Richland Memorial Hospital

1996 Member, Internal Review Committee, Graduate Medical Education, Richland Memorial Hospital

1997-2000 Member, Cooperative Staff of Center for Cancer Treatment and Research

1997-2000 Member, Curriculum Committee, University of South Carolina School of Medicine

PUBLIC SERVICE and CIVIC ACTIVITIES:

Public media interview, WLTX TV, Columbia, "Floaters and their Implications" program (host Phyllis Dean, WIS news) July 29, 1997

Public media interview, WSCQ TV, Columbia, "Prevention of Ocular trauma and Precautions On a July 4 weekend " program (host Mike Suber, WIS news) June 28, 1996

Public media interview, Carolinian Magazine, Columbia, "Treatment of AIDS patients with a new Intra ocular device" Reporter: Karen White, June 26, 1997

Associate Examiner to American Board of Ophthalmology, since July 1995.

Diabetic Retinopathy and Glaucoma Screening in conjunction with South Carolina Eye Institute, South Carolina Commission of the Blind and Lions Club, March 22-25, 1996

Diabetic Retinopathy and Glaucoma Screening in conjunction with South Carolina Eye Institute, at State Fair, August 27-29, 1996, Columbia, South Carolina

Diabetic Retinopathy and Glaucoma Screening in conjunction with South Carolina Eye Institute, at State Fair, September 2-6, 1995, Columbia, South Carolina

Consultant, Ophthalmology Service, Ryan White Free AIDS Clinic, Columbia, South Carolina, July 1995-December 2000. Provide free preventive screening for Indigent Patients.

Participant, Annual Diabetic Screening in Conjunction with Parkland Memorial Hospital Outreach program for Indigent Population, 1992-94

Participant, Weekly free clinic in Conjunction with Catholic Charities Church program, Jamaica, New York, August 88- June 92.

Volunteer Resident Member, Lions Eye Club, Queens, New York, Procured Donor eyes for corneal transplantation, 89-92.

Participated and performed over 1000 free cataract surgeries 1980-83, under the auspices of the Rotary Club in the provinces of Haryana and Punjab, India.

Mentor, Minority Students, Bedford-Stuyvesant section, Brooklyn, New York, 90-92 academic years.

Member, Richland Memorial Hospital Curriculum development committee on role of medical ethics in graduate medical education, 1995-97.

Participant, National Eye Care project sponsored by American Academy of Ophthalmology, 1994-present

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Active participant, Operation sight saver (Sponsor: Commission for the Blind) to provide NO COST surgery with care to needy diabetics who otherwise could not afford care in an attempt to eliminate preventable blindness in South Carolina

Member, Board of Directors, AVASC Foundation, 1998-present, New York

ADMINISTRATIVE EXPERIENCE:

Chairman, Department of Ophthalmology, University of Florida College of Medicine, Jacksonville, Florida, 11/99-present

Residency and Fellowship Program Director, Department of Ophthalmology, University of Florida School of Medicine, Jacksonville, Florida, 11/99-present

Chief Administrative Officer, Department of Ophthalmology, University of Florida College of Medicine, Jacksonville, Florida, 11/99-present

Residency Program Director, Department of Ophthalmology at University of South Carolina School of Medicine since 6/94 – 11/99

Administrative Chief Resident in charge of organizing day to day residency activities at CMC Ophthalmology program, 07/91 - 06/92

President of House Staff body of 450 resident members at Catholic Medical Center during residency

Extensive RRC review experience: Collected data and prepared relevant documentation for RRC visit during chief residency year in 1992 as well as program director in 1997. Full accreditation was awarded on both occasions.

CLINICAL EXPERIENCE:

Director, Vitreoretinal service, University of Florida School of Medicine, Jacksonville, Florida, 1999-Present

Director, Neuro-ophthalmology and Electrophysiology service, University of Florida School of Medicine, Jacksonville, Florida, 1999-Present

Director, Vitreoretinal service, University of South Carolina School of Medicine, 1994-1999

Director, Neuro ophthalmology and Electrophysiology service, University of South Carolina School of Medicine, 1994-99

Extensive experience in vitreo-retinal surgery including management of advanced PVR with modern molecular biological agents, severe diabetic traction retinal detachments, Phakoemulsification combined with vitrectomy and severe ocular trauma. Performed over 10,000 procedures as primary surgeon

Specially trained in using Wide angle Vitrectomy system, Perfluorocarbon liquids and placement of telescopic implants and therapeutic intraocular implants

Fellowship trained in the management of Ocular tumors during Ocular oncology fellowship at MD Anderson Cancer Center, UT Houston, Texas

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Organized Neuro-ophthalmology clinic and supervised Electrophysiology laboratory during Neuro-ophthalmology fellowship

TEACHING EXPERIENCE:

Grand rounds coordinator, University of Florida/Shands Jacksonville Ophthalmology Residency Program, Jacksonville, Florida, 2000-present

Grand rounds coordinator, Richland Memorial Hospital/University of South Carolina Ophthalmology Residency Program, Columbia, SC 1994-Present

Preceptor, University of South Carolina School of Medicine Students on surgery rotation and Family practice residents of Richland Memorial Hospital 1994-2000

Medical Student Advisor, University of South Carolina School of Medicine, 1994-2000

Organizer: Didactic and Microscopic surgery courses to new residents instructing phacoemulsification and basic surgical retinal skills.

Co-director, Clinical Ophthalmology section of Physical Diagnosis, Course # D603/4, M-II, The University of South Carolina School of Medicine, 1994 - 2000

Co-director, Clinical Ophthalmology section of Physical Diagnosis, Course # D620, M-IV, The University of South Carolina School of Medicine, 1994 - 2000

Co-director, Family Practice resident Ophthalmology rotation, Richland Memorial Hospital, 1994-2000.

Co-director, Internal Medicine resident Ophthalmology rotation, Richland Memorial Hospital, 1994-2000.

RESEARCH EXPERIENCE:

Grants-in-Aid

1. Principal investigator of NIH grant: "Ischemic Optic Neuropathy Decompression Trial, Follow up study" 1997-2002. UIO EY09566-04 ($48,000)

2. Principal investigator of NIH grant: "Ischemic optic Neuropathy Decompression Trial" 1991-1996. UIO EY09566-03 ($134,000)

3. Principal investigator of NIH Grant: “Phase III Trial-AREDS II- A Multi-Center, Randomized Trial of Lutein, Zeaxanthin, and Omega-3 Fatty Acids in Age-Related Macular Degeneration.” Sponsor National Eye Institute N01-EY-5-0007 ($126,000)

4. Principal investigator of NIH Grant “Evaluation of Vitrectomy for Diabetic Macular Edema.” Sponsor Diabetic Retinopathy Clinical Research Network (DRCRnet); National Eye Institute UIO EY14231 ($164,000)

5. Principle Investigator of NIH Grant “Intravitreal Ranibizumab or Triamcinolone Acetonide in Combination with Laser Photocoagulation for Diabetic Macular Edema”. Sponsor. Diabetic Retinopathy Clinical Research Network (DRCRnet); National Eye Institute UIO EY14242 ($522,000)

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6. Consultant for NIH grant: “Collaborative Image Annotation in Ophthalmology UIO EY09566-03. 2003-04 ($98,000)

7. Principle Investigator of “A Double-Masked, Placebo-Controlled, Parallel-Group, Multi-center, Dose-Ranging Study to Assess the Efficacy and Safety of LX211 as Therapy in Subjects with Active Sight Threatening, Non-Infectious Anterior Uveitis”. Sponsor. Lux Biosciences, Inc.

8. Principal investigator of “A Prospective Continuation Multicenter Clinical Trial of the Implantable Miniature Telescope (IMT) In patients with Central Vision Impairment Associated with Age-Related Macular Degeneration.” Sponsor VISIONCARE Ophthalmic Technologies ($30,000)

9. Co-Investigator of “A Phase II/III Study of Encapsulated Human NTC-201 Cell Implants Releasing Ciliary Neurotrophic Factor (CNTF) for Participants with Retinitis Pigmentosa Using Visual Acuity as the Primary Outcome”. Sponsor. Neurotech USA, Inc. (160,000$)

10. Principal investigator of “A Phase 3 Multicenter, Randomized, Double-Masked, Controlled Study of Squalamine Lactate (MSI-1256F) for Injection for the Treatment of Subfoveal Choroidal Neovascularization Associated with Age-Related Macular Degeneration” Sponsor: Gaenera Corporation project no MSI-1256F-301. ($270,000)

11. Principal investigator of " A multi center randomized controlled study to evaluate the safety and efficacy of oral gancyclovir in comparison to intravitreal Gancyclovir implant in patients with newly diagnosed cytomegalovirus retinitis. Sponsor Syntex Project GANS. 2304 ($160,000)

12. Principal investigator of " A 12 Week, Multi-center, randomized, double-masked, three treatment parallel group comparison of fixed combination of latanoprost and timolol vs. latanoprost vs.timolol in glaucoma patients with optic nerve head abnormalities and visual field defects ” Sponsor Pharmacia Project Xalcom. 912-OPT-0076-022 ($47,000)

13. Principal investigator of " A multi center randomized, double masked, controlled study to evaluate the safety and efficacy of an intravitreal Flucinolone Acetonide (0.5 or 2 mg) Implant in Patients with Diabetic Macular Edema. Sponsor: Bausch & Lomb Incorporated Project BL 415-007 ($400,000)

14. Principal investigator of " A multi center randomized, double masked, controlled study to evaluate the safety and efficacy of an intravitreal Flucinolone Acetonide (0.5 or 2 mg) Implant in Patients with Noninfectious Uveitis Affecting the Posterior Segment of the Eye. Sponsor: Bausch & Lomb Incorporated Project BL 415-001 ($170,000)

15. Principal investigator of “A Safety and Efficacy Assessment of Chimeric Ribozyme to PCNA to Prevent Recurrence of Proliferative Vitreoretinopathy. Sponsor: Immusol Corp. Project IM-VIT 100 ($17,000)

16. Principal investigator of “Retinopathy of Prematurity screening in pre-term babies”. Sponsor. Childrens Miracle Network. 2000-2001 ($64,000).

17. Principal investigator of “Electrophysiology Diagnostic Service for children with Retinopathy of Prematurity in North East Florida”. Sponsor. Children’s Miracle Network. 2001-2002 ($35,000)

18. Co-investigator of “Glaucoma and Diabetic Retinopathy Screening and Awareness in South Carolina - A Blindness Prevention Project. Sponsor: South Carolina Commission for the Blind ($15,000)

19. Co-investigator of “Oxidation in micro vascular disease”. Sponsor South Carolina Consortium for Cardiovascular Disease and Stroke, 1997 - 98 ($17,000)

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20. Co-Investigator of “Use of perfluorocarbon liquids in management of complex retinal detachments " a pilot study conducted at UT Southwestern Medical School. 1992- 94

21. Co-investigator of “Effects of vitreous on metalloproteinase activity in retinal pigment cells” Sponsor South Carolina Consortium for Cardiovascular Disease and Stroke, 1997 - 98 (20,000$).

22. Co-investigator of “Anti PDGF antibodies effectively inhibit RPE induced collagen contraction in Proliferative Vitreoretinopathy.” Sponsor. Palmetto Richland Health alliance, 1997-98 (5000$).

23. Co-investigator of “Apoptosis of the retinal pigment epithelial and photoreceptor cells in Age Related Retinal Degeneration” Sponsor. Palmetto Richland Health alliance, 1998-99 (5000$).

24. Co-investigator of “Acquisition of instrumentation for the development of novel environmentally conscious manufacturing processes employing water jet technologies” Sponsor. National Science Foundation. 1998-99 (840,240$).

25. Co-investigator of “A Randomized double blind, Phase III comparative trial of 2 doses of ZD1839 (TRESSA) in combination with paclitaxel and carboplatin versus placebo in combination with paclitaxel and carboplatin in chemotherapy-naïve patients with advanced (stage III or IV non-small cell lung cancer”. Sponsor. AstraZeneca Pharmaceuticals inc. 2000-2002 (350,000$)

26. Co-investigator of “A Study to evaluate the safety and Efficacy of TAK-37 versus Placebo in Subjects with Irritable Bowel Syndrome”. Sponsor. MDS Pharma Services. 2000-2002 (350,000$)

SCIENTIFIC REVIEWER :

Ophthalmology

Experimental Eye Research

International Journal of Ocular Pharmacology

Archives of Ophthalmology

Current Eye Research

Focal Points in Ophthalmology

Investigative Ophthalmology and Visual Science

Retina

European Journal of Ophthalmology

British Journal of Ophthalmology

Journal of Medical Case Series

BMC Ophthalmology

Neuroscience Research

Indian Journal of Ophthalmology

Cutaneous and Ocular Toxicology

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MAJOR INTERESTS:

Clinical:

Vitreo-retinal Diseases and Surgery; Uveitis and Ocular Oncology;

Neuro-Ophthalmology

Current Research:

Optical lens designing for vitrectomy systems

Retinal Stem cell Isolation and transplantation

Design of synthetic biological and chemical agents that facilitate vitreolysis

Neuronal regeneration and retinal transplants using neural cell cultures

Glutamate metabolism in retinal ganglion cells and evaluation of gene therapy

BIBLIOGRAPHY:

Contributions to Books & Monographs: 1. Chalam KV: Ocular Pharmacology. In: BASIC AND CLINICAL SCIENCE COURSE, 1997-98,

Section 2: Fundamentals and Principles of Ophthalmology. ed. R.C. Tripathi. American Academy of Ophthalmology, San Francisco. 1997, p381-450

2. Tripathi BJ, Tripathi RC, and Chalam KV: Eye Anatomy. In ENCYCLOPEDIA OF HUMAN

BIOLOGY, ed. R. Dulbecco. 2nd edition. Academic Press, San Diego. 1997, p883-901 3. Tripathi BJ, Tripathi RC, Li J, Qian Y, Kosnosky W, and Chalam KV: Barotoxic effects on

morphology and viability of trabecular cells: A preliminary report. In ADVANCES IN OCULAR TOXICOLOGY, ed. K. Green, H.F. Edelhauser, R.B. Hackett, D.S. Hull, D.E. Potter, and R.C. Tripathi. Plenum Press, New York. 1997, p55-61

4. Bryan C, Li J, Tripathi BJ, Chalam KV, Pakalnis VA, Tripathi RC: Topical fluorescein application can

induce iritis and glaucoma: an unusual case report. In ADVANCES IN OCULAR TOXICOLOGY, ed. K. Green, H.F. Edelhauser, R B. Hackett, D.S. Hull, D.E. Potter, and R.C. Tripathi. Plenum Press, New York. 1997, p87-91

5. Weiss R, Chalam KV, Ellsworth R: Introduction to Imaging Techniques in Orbital and Ocular Tumors:

Radiology of Orbit. Editors: B Haik and M Mafee, Permagon Press 1991, p207-263 6. Tang R, Chalam KV, Musgrove K: Exercise induced oscillopsia in Arnold-Chairi Malformation:

NEURO-OPHTHALMOLOGY ENTERS NINETIES: ed: L. Smith. Dutton Press 1990, p199-207 7. Paton D, Craig J, and Chalam KV: Clinical Symposia: Management of cataracts: Vol 42 Number 4

1990 CIBA - GEIGY, p1-32

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8. Tang R, Chalam KV: Ophthalmic manifestations in systemic disease: A Slide Script Manual. American Academy of Ophthalmology, San Francisco. 1990, p1-32

9. Chalam KV: HLA - Typing in recurrent herps simplex keratitis, Thesis accepted in partial fulfillment of

Masters degree in Ophthalmology. Post Graduate Medical Institute, Chandigarh, PGI Press, India 1983, p1-132.

10. Chalam, KV., Lawler, J. Management of Diabetic Retinopathy in the New Millennium. Jacksonville

Medicine 51: 8, 2000 11. Chalam KV: Ocular Pharmacology. In: BASIC AND CLINICAL SCIENCE COURSE, 1998-99, Section

2: Fundamentals and Principles of Ophthalmology. ed. R.C. Tripathi. American Academy of Ophthalmology, San Francisco. 1998, p381-450

12. Chalam KV: Ocular Pharmacology. In: BASIC AND CLINICAL SCIENCE COURSE, 1999-00, Section










17. Chalam KV: An in vitro model to study the effect of hydrostatic pressure on retinal ganglion cells and

its relevance to Glaucomatous eye disease. Thesis accepted in partial fulfillment of Doctor of Philosophy degree. University of South Carolina, Columbia. 2004, p1-212.

18. Chalam KV, Lin S. Management of Diabetic Retinopathy in 21st Century. Jacksonville Medicine (In

press)

Peer Reviewed Journals:

2011

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1. Murthy RK, Grover S, Chalam KV. Temporal macular thinning on Spectral-domain Optical Coherence Tomography in proliferative sickle cell retinopathy. Archives of Ophthalmology 2011 In press

2. Chalam KV, Balaiya S, Mylyappa RS, His W, Brar VS,Murthy RK. Evaluation of choroidal endothelial cell proliferation after exposure to varying doses of proton beam radiation.. Retina in press

3. Chalam KV, Gupta SK, Brar VS, Murthy RK. Spectral domain OCT features of multiple subfoveal retinal pigment epithelial tears after intravitreal bevacizumab. Indian Journal of Ophthalmology. 59(1): 47-8

4. Browning DJ, Apte RS, Bressler SB, Chalam KV, Danis RP, Davis MD, Kollman C, Qin H, Sadda S, Scott IU; FOR THE DIABETIC RETINOPATHY CLINICAL RESEARCH NETWORK., Association of the the extent of Diabetic macular edema as assessed by Optical Coherence Tomography with visual acuity and retinal outcome variables - Retina. 23 (6):815-820, 2011 (J protocol)

5. DIABETIC RETINOPATHY CLINICAL RESEARCH NETWORK, Elman MJ, Aiello LP, Beck RW, Bressler NM, Bressler SB, Edwards AR, Ferris FL, Friedman SM, Glassman AR, Miller KM, Scott IU, Stockdale CR, Sun JK. Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology. 117 (6):1064-77, 2011 (2 year results)

6. DIABETIC RETINOPATHY CLINICAL RESEARCH NETWORK, Elman MJ, Aiello LP, Beck RW, Bressler NM, Bressler SB, Edwards AR, Ferris FL, Friedman SM, Glassman AR, Miller KM, Scott IU, Stockdale CR, Sun JK. Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Archives of Ophthalmology. 117 (6):1064-77, 2011 (Digital vs Film evaluation)

7. DIABETIC RETINOPATHY CLINICAL RESEARCH NETWORK, Elman MJ, Aiello LP, Beck RW, Bressler NM, Bressler SB, Edwards AR, Ferris FL, Friedman SM, Glassman AR, Miller KM, Scott IU, Stockdale CR, Sun JK. Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Archives of Ophthalmology. 117 (6):1064-77, 2011 (clinical examples of I Protocol results)

8. Browning DJ, Apte RS, Bressler SB, Chalam KV, Danis RP, Davis MD, Kollman C, Qin H, Sadda S, Scott IU; FOR THE DIABETIC RETINOPATHY CLINICAL RESEARCH NETWORK., Association of the the extent of Diabetic macular edema as assessed by Optical Coherence Tomography with visual acuity and retinal outcome variables - Retina. 23 (6):815-820, 2011 (VA vs OCT in I protocol))

9. Chalam KV, Balaiya S, Mylyappa RS, His W, Brar VS,Murthy RK. Evaluation of choroidal endothelial cell proliferation after exposure to varying doses of proton beam radiation.. Retina in press (retinal dyes)

10. Murthy RK, Grover S, Chalam KV. Sequential spectral domain OCT documentation of retinal changes after branch retinal artery occlusion. Clinical Ophthalmology 2011; 4:327-9

2010

11. Sharma RK, Rogojina AT, Chalam KV. Bevacizumab therapy normalizes the pathological intraocular environment beyond neutralizing VEGF. Molecular Vision 16: 2175-84,2010

20 10/10/11

12. Sharma RK, Balaiya S, Chalam KV. Bevacizumab suppression of establishment of micrometastasis in experimental ocular melanoma Investigative Ophthalmology & Visual Science. 51(12):6, 2010

13. Brar VS, Sharma RK, Murthy RK, Chalam KV. Bevacizumab neutralizes the protective effect of Vascular Endothelial Growth Factor on Retinal ganglion cells. Molecular Vision 16: 2175-84, 2010

14. Murthy RK, Brar VS, Chalam KV. Evaluation of ultra wide angle „ora-ora‟ high refractive index self-stabilizing contact lens for vitreous surgery. Retina 30(9):1551-3, 2010

15. Ambatipudi, S, Goyal J, Shah GY, Pathangey A, Das T, Chalam KV. Novel dyes in intraocular surgery. American Journal of Ophthalmology 150(3):442-3, 2010

16. Murthy RK, Storm L, Grover S, Chalam KV. In-vivo high resolution imaging of Optic Nerve Head Drusen using Spectral- domain Optical Coherence Tomography. BMC Medical Imaging 10:11, 2010

17. Murthy RK, Grover S, Chalam KV. Sequential spectral domain OCT documentation of retinal changes after branch retinal artery occlusion. Clinical Ophthalmology 2010; 4:327-9

18. DIABETIC RETINOPATHY CLINICAL RESEARCH NETWORK, Elman MJ, Aiello LP, Beck RW, Bressler NM, Bressler SB, Edwards AR, Ferris FL, Friedman SM, Glassman AR, Miller KM, Scott IU, Stockdale CR, Sun JK. Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology. 117 (6):1064-77, 2010

19. Murthy RK, Chalam KV. Assistant Independent OptiFlex system for contact as well as non contact wide angle viewing in vitreo-retinal surgery. Archives of Ophthalmology 128(4):490-2, 2010

20. DIABETIC RETINOPATHY CLINICAL RESEARCH NETWORK,Writing committee, Haller JA, Qin H, Apte RS, Beck RW, Bressler NM, Browning DJ, Danis RP, Glassman AR, Googe JM, Kollman C, Lauer AK, Peters MA, Stockman ME. Vitrectomy outcomes in eyes with diabetic macular edema and vitreomacular traction. Ophthalmology. 117 (6):1087-93, 2010

21. Chalam KV, MurthyRK, Gupta SK, Brar VS. Spectral-domain OCT guided photodynamic therapy for choroidal hemangioma. Cases Journal. 2: 8778, 2010

22. Balaiya S, Murthy RK, Brar VS, Chalam KV. Evaluation of Ultraviolet light toxicity on cultured Retinal Pigment Epithelial and Retinal Ganglion cells. Clinical Ophthalmology 4:33-9, 2010

23. Chalam KV, Gupta SK, Brar VS, Murthy RK, Grover S. Foveal structure delineated by Spectral-domain Optical Coherence Tomography correlates with visual function after Macular Hole surgery. European Journal of Ophthalmology 2010; 20(3):572-7

24. Chalam KV Balaiya S, Murthy RK. Accurate estimation of Vascular Endothelial Growth Factor levels in micro samples with a low cost bead based assay. Retina 2010; 30(5):815-9

25. Grover S, Murthy RK, Brar VS, Chalam KV. Comparison of retinal thickness in normal eyes using Stratus and Spectralis Optical Coherence Tomography. Investigative Ophthalmology & Visual Science. 2010; 51(5):2644-7

26. Chalam KV, Murthy RK. Spectral domain OCT documented resolution of pseudophakic cystoid macular edema after intravitreal Triamcinolone. Ophthalmology and Eye diseases 2010;2:1-4

.

2009

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27. Kelmenson, AT, Brar VS, Chalam KV. Fundus autoflourescene and microperimetry detect Plaquenil toxicity before changes in visual acuity European Journal of Ophthalmology

28. Chalam KV, Murthy RK. Spectral domain OCT features of hypotonous maculopathy after successful retinal detachment surgery. Retinal Cases and Brief Reports

29. Chalam KV, Shah VA. Modified portable digital camera for screening of diabetic retinopathy. Ophthalmic Research 28;42(1):60-62,2009

30. Chalam KV, Agarwal S, Brar VS, Murthy RK, Sharma RK .Evaluation of cytotoxic effects of bevacizumab on human corneal cells. Cornea 28(3):328-33,2009

31. Browning DJ, Apte RS, Bressler SB, Chalam KV, Danis RP, Davis MD, Kollman C, Qin H, Sadda S, Scott IU; FOR THE DIABETIC RETINOPATHY CLINICAL RESEARCH NETWORK., Association of the the extent of Diabetic macular edema as assessed by Optical Coherence Tomography with visual acuity and retinal outcome variables - Retina. 23 (6):815-820, 2009

32. Grover S, Sharma R, Chalam KV. Intracameral Bevacizumab Effectively Reduces Aqueous VEGF in Neovascular Glaucoma British Journal of Ophthalmology 93(2):273-4,2009

33. Gupta S, Syed F, Murthy RK, Brar VS, Chalam KV. Sinonasal lymphoma masquerading as persistent blepharoconjunctivitis. Orbit ,28(1):34-6,2009

34. Grover S, Murthy RK, Brar VS, Chalam KV. Normative Data for Macular Thickness by High-Definition Spectral-Domain Optical Coherence Tomography (Spectralis). American Journal of Ophthalmology 148(2): 266-71,2009

35. Sharma RK, Chalam KV,. In vitro evaluation of bevacizumab toxicity on retinal ganglion cell line, Acta Ophthalmologica, 87(6):618-22,2009

36. Sharma RS, Chalam KV,. Multiplex immunoassay analysis of biomarkers in clinically accessible quantities of human aqueous humor , Molecular Vision, 15:60-9 . 2009

37. Parappuam S, Chang B, Li L, Hartung R, Chalam, KV., Hunt DM., Hunt, RC.,Differential effects of TGF Beta and Vitreous on the transformation of Human Pigment Epithelial Cells. Investigative Ophthalmolology and Visual Science 50(12)5965-74, 2009

38. Chalam KV, Murthy RK, Agarwal S, Gupta S, Grover S. Comparative Efficacy of Topical Tetravisc vs. Lidocaine Gel in Cataract Surgery. BMC Ophthalmology 9:7,2009

39. Brar VS, Sharma RK, Murthy RK, Chalam KV. Evaluation of differential toxicity of varying doses of Bevacizumab on retinal ganglion cells, retinal pigment epithelial cells and vascular endothelial growth factor enriched choroidal endothelial cells. Journal of Ocular Pharmacology and Therapeutics.25(6):507-11, 2009

40. Balaiya S, Murthy RK, Brar VS, Chalam KV. Effects of Indocyanine Green on Cultured Retinal Ganglion Cells In-Vitro. BMC research notes 2: 236, 2009

41. Brar VS, Murthy RK, Chalam KV. Functional microperimetry and SD-OCT confirm consecutive retinal atrophy from optic nerve pit. Clinical Ophthalmology.3:625-8, 2009

42. Shah VA, Chalam KV. Values for Macular Perimetry Using MP-1 microperimeter in Normal Subjects. Ophthalmic Research. 41(1):9-13, 2009

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2008

43. Chalam KV, Gupta SK, Brar V. Inverse Argyll Robertson Pupil in Burkitt‟s Lymphoma. Clinical

Ophthalmology 2(1):1-4, 2008

44. Chalam KV, Brar VS, Agarwal S. Direct Image Creating Aspheric Lens for Indirect Ophthalmoscopy. Ophthalmic Research.2007. 40(2):94-7, 2008

45. Chalam KV, Gaurav Y Shah, Swati Agarwal, Shailesh Gupta. Illuminated Curved 25 Gauge Levels

Vitrectomy Probe for removal of Subsclerotomy Vitreous in Vitreoretinal Surgery. Indian Journal of Ophthalmology. 56(4):331-4,2008.

46. Gupta S, Brar VS, Murthy RK, Chalam KV., Aplastic anemia induced disc edema and visual loss in pregnancy: a case report. Cases Journal. 2008;1(1):322- 4

47. Chalam KV, Shailesh Gupta, Sandeep Grover, Swati Agarwal. Intracameral Avastin Dramatically

Resolves Iris Neovascularization and Reverses Neovascular Glaucoma. European Journal of Ophthalmology 18(2):255-62, 2008

48. Chalam KV, Tina Tillis, Syed F, Agarwal S. Acute Bilateral Simultaneous Angle Closure Glaucoma

after Topiramate Administration: a case report. J Med Case Reports 8;2:1, 2008 49. Chalam KV, Sharma Rk, Murthy RK. Limitations and difficulties in assessing nerve growth factor

levels in aqueous humor samples from human eyes. BMC Research Reports 1:22, 2008 50. Chalam KV, RK Murthy, Brar VS. Spectral domain Optical Coherence Tomography documented

resolution of recalcitrant macular edema after intravitreal Bevacizumab in Branch Retinal Vein Occlusion. European Journal of Ophthalmology. 2008 18 (5): 831-3

51. Chalam KV, Murthy RK. Reusable sutureless silicone ring for housing contract lens during vitreoretinal surgery. Retina 28 (10):1550-1, 2008

52. Browning DJ, Glassman AR, Aiello LP, Bressler NM, Bressler SB, Danis RP, Davis MD, Ferris FL, Huang SS, Kaiser PK, Kollman C, Sadda S, Scott IU, Qin H; Diabetic Retinopathy Clinical Research Network: Diabetic retinopathy research Network team: Optical Coherence Tomography measurements and analysis methods in optical coherence tomography studies of diabetic macular edema. (University of Florida, Chalam, K.V, P.l.) Ophthalmology. 115 (8):1366-71, 2008

53. Callanan DG, Jaffe GJ,, Martin DF, Pearson PA, Comstock TL, and Fluocinolone Acetonide Uveitis Study Group: Treatment of Posterior Uveitis with a Fluocinolone Acetonide Implant (Retisert) : Three year clinical results (University of Florida, Chalam, K.V, P.l.). Archives of Ophthalmology 126(9): 1191-201, 2008.

http://www.ncbi.nlm.nih.gov/pubmed/19229743?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

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2007

54. Chalam KV, Gupta SK, Swati Agarwal. Rituximab Effectively Reverses Papilledema Associated with Cerebral Venous Sinus Thrombosis in Anti Phospholipid Antibody Syndrome. European journal of Ophthalmology. 5:867-70, 2007

55. Chalam KV, Amit Chokshi, Swati Agarwal, Deepak Edward. Complications of Alphacortm Keratoprosthesis- A Clinicopathologic Report. Cornea 26(10):1258-60,2007

56. Chalam KV, Swati Agarwal, Gupta SK. Light Weight Autoclavable Wide-Angle Contact Lens for Vitreous Surgery. Ophthalmic Surg Lasers Imaging. 38(6):523-4,2007

57. Chalam KV, Swati Agarwal, Gupta SK Recovery of Retinal sensitivity after branch retinal artery occlusion. Ophthalmic Surg Lasers Imaging. 38(4):328-9, 2007

58. Chalam KV, Vinay Shah. 20G Illuminated Curved Vitrectomy Probe for Vitreoretinal Surgery

Ophthalmic Surg Lasers Imaging. 2007. 38(4):525-6, 2007

59. Scherer RW, Feldon SE, Levin L, Langenberg P, Katz J, Keyl PM, Wilson D,. Kelman SE, Dickersin K, and Ischemic Optic Neuropathy Decompression Trial Research Group: Visual Fields at Follow-up in the Ischemic Optic Neuropathy Decompression Trial (South Carolina Eye Institute, Chalam, K.V, P.l.): Evaluation of Change in Pattern Defect and Severity Over Time Ophthalmology. 125:1161-1167, 2007

60. William M. Schiff, MD; John C. Hwang, MD; Michael D. Ober, MD; Jeffrey L. Olson, MD; Elona Dhrami-Gavazi, MD; Gaetano R. Barile, MD; Stanley Chang, MD; Naresh Mandava, MD: Safety and Efficacy Assessment of Chimeric Ribozyme to Proliferating Cell Nuclear Antigen to Prevent Recurrence of Proliferative Vitreoretinopathy (University of Florida, Chalam, K.V, P.l.) Archives of Ophthalmology. 125:1161-1167, 2007

61. Hartung R, Ganti R, Parappuam S, Chalam, KV., Hunt DM., Hunt, RC.,Vitreous induces heme oxygenase-1 expression mediated by transforming growth factor-β and reactive oxygen species generation in human retinal pigment epithelial cells. Molecular Vision. 13:66-78, 2007

62. Sharma RS, Chalam KV,. Letter. Scratch Technique and evaluation of cytotoxicity of Bevacizumab. British Journal of Ophthalmology . 2007

63. Sharma RS, Chalam KV,. Letter. Experimental conditions and RPE cytotoxicity. Investigative Ophthalmology and Visual Science. 2007

64. Sharma RS, Chalam KV,. Letter. In appropriate choice of animal age for investigating retinal progenitor cells,. Investigative Ophthalmology and Visual Science. 2007

2006

65. Chalam KV, Shah V. Resolution of macular scotoma after radial optic neurotomy in central retinal vein occlusion. Ophthalmic Surgery, Lasers and Imaging. 37(1):72-5,2006

http://archopht.ama-assn.org/cgi/content/full/125/9/1161#AUTHINFO#AUTHINFOhttp://archopht.ama-assn.org/cgi/content/full/125/9/1161#AUTHINFO#AUTHINFO

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66. Chalam KV, Gupta SK, Shah GY, Agarwal S. Successful management of melanocytoma associated CNV with Photodynamic Therapy. European Journal of Ophthalmology. 16(5): 776-8

67. Chalam KV, Shah GY, Rappaport k, Shah VA. Choroidal neovascularization associated with ocular melanocytoma of the optic disc. Retina 26(6):703-4, 2006

68. Chalam KV, Shah GY, Shah VA. Evaluation of web based Annotation of ophthalmic Images for multi-center clinical trials. Indian Joural of Ophthalmology 54(2):126-9, 2006

69. Chalam, KV, IONDT Research Group: Development and validation of a computerized expert system for evaluation of automated visual fields from the Ischemic Optic Neuropathy Decompression (South Carolina Eye Institute, Chalam, K.V, P.l.). BMC Ophthalmology 6: 34-42, 2006.

70. Glenn J. Jaffe MD, Daniel Martin MD, David Callanan MD, P. Andrew Pearson MD, Brian Levy OD, MS, Timothy Comstock OD, MS and Fluocinolone Acetonide Uveitis Study Group: Fluocinolone Acetonide Implant (Retisert) for Noninfectious Posterior Uveitis ,Thirty-Four–Week Results of a Multicenter Randomized Clinical Study (University of Florida, Chalam, K.V, P.l.). Ophthalmology 113: 1020-27, 2006.

71. Shah VA, Shah GY, Chalam KV, Letter Endophthalmitis following 25-guage vitrectomy Eye. 20(6):735-36, 2006

72. Shah V. Chalam KV. Letter regarding correlation of retinal sensitivity measured with fundus related microperimetry to visual acuity and retinal thickness in eyes with diabetic macular oedema. Eye. 20 (11) 1307-08, 2006

2005

73. Chalam KV, Shah GY. Letter. Vitrectomy with or without arteriovenous adventitial sheathotomy for macular edema associated with branch retinal vein occlusion. American Journal of Ophthalmology 139 (6):1146, 2005

74. Chalam KV, Shah VA. Two piece Dual Purpose Comprehensive Contact Lens system for Vitreous surgery. Ophthalmic Research 37(4):175-178, 2005

75. Chalam KV, Gupta SK, Agarwal S, Shah V. Sutureless Limited Vitrectomy for Positive Vitreous Pressure in Cataract Surgery. Ophthalmic Surgery, Lasers and Imaging 36:518- 522, 2005

76. Chalam KV, Shah VA. Severe Bilateral Posterior Ischemic Optic Neuropathy as a Complication of Spinal Surgery. Eye 19(3):367-8, 2005

77. Shah VA, Chalam KV. Intraocular Central Retinal Vein. Ophthalmic surgery, lasers and Imaging 36(2):174-6, 2005)

2004

78. Chalam KV, Shah VA. Successful Management of Cataract Surgery Associated Vitreous Loss with Sutureless Small Gauge Pars Plana Vitrectomy. American Journal of Ophthalmology 138(1): 79-84, 2004

25 10/10/11

79. Chalam KV, Shah VA, Tripathi RC. A curved vitrectomy probe. Ophthalmic surgery, lasers and Imaging 35(3):259-260, 2004

80. Chalam KV, Shah VA. Macular Infarction a presentation of Sickle Cell Crisis. Eye 18(12): 1277-8, 2004

81. Chalam KV, Shah VA. Self-Illuminated Contact Lens for Peripheral Vitreous Surgery. Ophthalmic Surgery Laser and Imaging 35(1): 76-77, 2004

82. Chalam KV, Pakalnis VA, Shah VA, Tripathi RC, Tripathi BJ, Yee D. Cataract in Kniest Dysplasia: Clinicopathological Correlation. Archives of Ophthalmology 122(6): 913-915, 2004

83. Chalam KV, Shah VA. A newly designed guarded radial neurotomy knife. Retina 24(5) 817-8, 2004

84. Chalam KV, Shah VA. Suction Assisted Self-Retaining two piece non-cased wide-angle Contact Lens for Vitrectomy. Ophthalmic surgery, lasers and Imaging 35(4):345-6 2004

85. Chalam KV, Shah VA. Optics of wide-angle panoramic viewing system assisted vitreous surgery. Survey of Ophthalmology 49(4): 437-445, 2004

86. Chalam KV, Shah VA. Self-Retaining Contact Lens system for Vitreous Surgery. Indian Journal of Ophthalmology. 52(1): 67-71, 2004

87. Chalam KV, Shah VA. Small Contact surface minified wide angle contact lens for pediatric vitreous surgery. Journal of Pediatric Ophthalmology & Strabismus 41(2): 109-111, 2004

88. Chalam KV, Vinjamaram S, Shah VA. Slitlamp Biomicroscopy adapter for simultaneous photodocumentation during clinical assessment. Journal of Cataract and Refractive Surgery. 34(8):1808-9, 2004

89. Chalam, KV, Shah VA. Liquid crystal display microperimetry in eyes with macular pathology. Indian Journal of Ophthalmology 52(4): 293-6, 2004

90. Chalam KV, Shah VA. Author‟s reply. Successful Management of Cataract Surgery Associated Vitreous Loss with Sutureless Small Gauge Pars Plana Vitrectomy. American Journal of Ophthalmology 138(6): 1091, 2004

91. Chalam KV. Author‟s reply. Small Gauge Sutureless pars plana Vitrectomy to manage Vitreous Loss during Phakoemulsiification. Journal of Cataract and Refractive Surgery 30(11):2253, 2004

92. Shah VA, Gupta, SK, Shah VK, Vinjamaram S, Chalam KV: TTO utility scores measure quality of life in patients with visual morbidity due to diabetic retinopathy or ARMD Ophthalmic Epidemiology. 11(1):43-51, 2004

93. Shah VA, Chalam KV. Congenital Retinal Macrovessel Causes reduced Retinal sensitivity at the Macula. European Journal of Ophthalmology 14(4):341-44, 2004

94. Shah VA, Chalam KV. Autoclavable two-piece non cased wide-angle contact lens system for vitrectomy. Ophthalmic Research 36(2):94-97, 2004

95. Shah VA, Chalam KV. Liquid Crystal Display Microperimetry in Idiopathic Subretinal Fibrosis. Ophthalmic Surgery and Lasers 35(4): 321-4, 2004

96. Shah VA, Chalam KV. Autoclavable Wide-Angle Contact Lens for Vitreous Surgery. American Journal of Ophthalmology 137(2): 359-60, 2004

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2003

97. Chalam KV, Patel CC, Shah VA. Newly Designed Self-Retaining Contact Lens for Vitreous Surgery. American Journal of Ophthalmology 135(4): 544-546, 2003

98. Chalam, K.V, Gupta SK, Vinjamaram S, Shah VA. Congenital Anomalous Retinal Artery associated with a Leaking Macroaneurysm- A Case Report. Archives of Ophthalmology. 121: 409-410, 2003

99. Chalam KV, Roche Gancyclovir Study Group. Endophthalmitis after gancyclovir implant in patients with AIDS and cytomegalovirus treated retinitis. (South Carolina Eye Institute, Chalam, K.V, P.l.) American Journal of Ophthalmology 136(4): 649-654, 2003

100. Chalam KV, Shah VA, Gupta SK, Tripathi RC. Evaluation of Lens and Peripheral Retinal Relationships with the Use of Newly Designed Curved Endolaser and Vitrectomy Probes. Retina 23 (6):815-820, 2003

101. Chalam KV, Gupta SK, Vinjamaram S, Shah VA. Small Gauge Sutureless pars plana Vitrectomy to manage Vitreous Loss during Phakoemulsiification. Journal of Cataract and Refractive Surgery 29:1482-1486, 2003

102. Chalam KV, Malkani S, Shah VA. Intravitreal Dexamethasone Effectively Reduces Postoperative Inflammation After Vitreoretinal Surgery. Ophthalmic Surgery and Lasers. 34 (3): 188-192; 2003

103. Chalam, KV, IONDT Research Group: Comparison of Information Obtained by Operative Note Abstraction to That Recorded on a Standardized Data Collection Form. (South Carolina Eye Institute, Chalam, K.V, P.l.) Surgery. 133: 324-330.2003.

104. Chalam, KV, IONDT Research Group: Surgical Quality Assurance in the Ischemic Optic Neuropathy Decompression Trial. (South Carolina Eye Institute, Chalam, K.V, P.l.) Controlled Clinical Trials. 24(3):294-305.2003

105. Shah VA, Chalam KV. Self-Stabilizing Wide-Angle Contact Lens for Vitreous Surgery. Retina 23:667-669, 2003

106. Shah VA, Chalam KV. Newly Designed Self-Retaining Prism Contact Lens for Vitreous Surgery. Retina 23:721-722, 2003

107. Shah VA, Chalam KV. Suction Assisted one piece Self-Retaining Wide-angle Contact Lens for Vitrectomy. Ophthalmic Research 35(3):170-172, 2003

108. Shah VA, Gupta SK, Chalam KV. Management of vitreous loss during cataract surgery under topical anesthesis with transconjunctival vitrectomy system. European Journal of Ophthalmology 13 (8): 693-6, 2003

2002

109. Chalam KV, Gupta SK, Tripathi, R.C., Gandham, S. Parsplana Modified Baerveldt Implant versus ND:Yag Cyclophotocoagulation in the Management of Neovascular Glaucoma. Ophthalmic Surgery and Lasers. 33: 383-393, 2002

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110. Chalam, K.V, Panthagani, P., Tripathi, R.C.: Metastatic Aspergillus Terreus Endophthalmitis secondary to Bone Infection in Immunocompromised Host. Annals of Ophthalmology. 34(2): 153-156, 2002

111. Chalam, KV, IONDT Research Group: The Fellow Eye in NAION: Report from the Ischemic Optic Neuropathy Decompression Trial Follow-up Study. (South Carolina Eye Institute, Chalam, K.V, P.l.) American Journal of Ophthalmology. 134: 317-328, 2002

2001

112. Das, T., Sharma, S., Singh, J., Rao, D.V., Chalam, KV.: Evaluation of Glutaraldehyde and Providone Iodine for sterilization of Wide Field Contact Vitrectomy Lenses. Ophthalmic Surgery and Lasers. 32(4): 300-304, 2001

2000

113. Chalam, KV, Li, J., Tripathi, R.C.: Occurrence of Atypical Acute Bilateral Multifocal Choroidal Neovascularization in Membranoproliferative Glomerulonephritis Type II. Annals of Ophthalmology 32(4):320-24, 2000

114. Chalam, KV, IONDT Research Group: The ischemic optic neuropathy decompression trial (IONDT): Twenty Four month update. (South Carolina Eye Institute, Chalam, K.V, P.l.) Archives of Ophthalmology. 118: 793-798, 2000

115. Malkani, S, Chalam, K.V., Tripathi, R.C. Funduscopic Changes in Ophthalmomyasis Interna, Digital Journal of Ophthalmology. 6(1):2000 [http://www.djo.Harvard.edu/GR/Malkani/Malkani0600.htm]

1999

116. Chalam, KV, Roche Gancyclovir Study Group. Oral gancyclovir in patients with cytomegalovirus treated with a gancyclovir implant: A randomized clinical trial. (South Carolina Eye Institute, Chalam, K.V, P.l.) New England Journal of Medicine. 340: 1063-1070, 1999

117. Tripathi, RC, Parapuram SK, Tripathi, BJ, Zhong Y, Chalam KV. Corticosteroids and Glaucoma Risk. Drugs and Aging 15(6):439-50,1999

118. Tsao K, Chalam, K.V., Pakalnis V.A, Tripathi, R.C. Occupational history is clue to unilateral Photic retinopathy, Journal of Ocular and Cutaneous toxicology. 18(1): 57-63, 1999

1998

119. Chalam, KV, IONDT Research Group: The ischemic optic neuropathy decompression trial (IONDT): Design and Methods. (South Carolina Eye Institute, Chalam, K.V, P.l.) Controlled Clinical Trials. 19: 276-298.1998

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120. Tripathi, RC., Li, J., Tripathi, BJ., and Chalam, KV., Adamis, AP. Increased level of vascular endothelial growth factor in aqueous humor of patients with neovascular glaucoma. Ophthalmology 105:232-237,1998

1997

121. Chalam, K.V. and Tripathi, R.C. Recurrent choroidal neovascular membrane from Toxoplasmic chorioretinal scar. Annals of Ophthalmology. 29: 306-308,1997

122. Chalam, KV, IONDT Research Group: Participation in the Ischemic Optic Neuropathy Decompression trial: Sex, race, and age. (South Carolina Eye Institute, Chalam, K.V, P.l.) Ophthalmic Epidemiology. 4:157-173.1997

123. Ambati J, Chalam KV, Chawla D, D'Angio CT, Guilet, EG, Rose SJ, Vanderlinde RE, Ambati BK. Elevated GABA, glutamate, and vascular endothelial factor levels in the vitreous of patients with proliferative diabetic retinopathy. Archives of Ophthalmology. 115: 1161-66. 1997

1996

124. Chalam, KV, IONDT Research Group: Characteristics of patients with nonarteritic ischemic neuropathy eligible for the ischemic optic neuropathy decompression trial. (South Carolina Eye Institute, Chalam, K.V, P.l.) Archives of Ophthalmology. 114: 1366-1374.1996

125. Tripathi, RC, Li J, Chalam KV, and Tripathi BJ. Expression of growth factor mRNAs by human Tenon's capsule fibroblasts. Experimental Eye Research. 63: 339-346, 1996.

126. Li J, Tripathi BJ, Chalam KV, Tripathi RC. Transforming growth factor beta 1 and 2 positively regulate TGF-1 beta mRNA expression in trabecular cells. Investigative Ophthalmolology and Visual Science. 37: 2778-2782, 1996

1995

127. Chalam, KV, IONDT Research Group: Optic nerve decompression surgery for Nonarteritic Anterior Ischemic optic neuropathy (NAION) is not effective and may be harmful. (South Carolina Eye Institute, Chalam, K.V, P.l.). Journal of American Medical Association 273: 625-632 .1995.

1985

128. Dhir S.P, Munjal VP, Chalam KV, Jain IS. : A retrospective study of lacrimal gland tumors, Indian Journal of Ophthalmology, 33(1): 47-49,1985.

Papers Submitted to Peer Reviewed Journals:

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129. Chalam KV, Shah VA. Flexcell Pressure Chamber: An In vitro system to study the effect of pressure on growth and morphology of retinal ganglion cells. Submitted to the Ophthalmic Research

130. Chalam, K.V, Malkani, S, Tripathi, R.C.: Intravitreal Triamcinolone effectively reduces postoperative inflammation after vitreoretinal surgery. Submitted to Retina

131. Tripathi, R.C., Li, J., Tripathi, B.J., Edward, D.P., Chalam, K.V., Li, T., Lin, N., Adamis, A. Evidence for Human Ciliary Epithelium as a Source of Synthesis and Secretion of Vascular Endothelial Growth Factor (VEGF) In Neovascular Glaucoma. Archives of Ophthalmology

Peer Reviewed Abstract Publications:

132. R Keshavamurthy,MD, VS Brar, MD, K.V. Chalam, MD, PhD. Foveal Microstructure Delineated by

Spectral-Domain OCT Correlates With Functional Outcome Mapped With Macular Microperimetry,

after Macular Hole Surgery American Academy of Ophthalmology, 2010

133. V.S. Brar, MD, S. Gupta, MD, S. Grover, MD, K.V. Chalam, MD, PhD . Reduction of Human Aqueous

VEGF Levels Accurately Predicts Resolution of Diabetic Macular Edema After Bevacizumab

Administration American Academy of Ophthalmology, 2010

134. KV Chalam,MD,PhD, R Keshavamurthy,MD, R Radhakrishnan,MD, VS Brar,MD, S Grover,MD.

Evaluation of modified retinopathy of prematurity screening guidelines using birth-weight as sole

inclusion criterion American Academy of Ophthalmology, 2010

135. KV Chalam,MD,PhD R Keshavamurthy,MD, V Brar MD. Ultrastructural anatomical changes noted on

high- resolution specitral domain oct accurately predicts visual acuity recovery after vitrectomy for

epiretinal membranes American Academy of Ophthalmology, 2010

136. R Keshavamurthy,MD, KV Chalam,MD,PhD, S Gupta, MD. Circumfrencial intraoperative laser

retinopexy eliminates the risk of retinal detachment after macuar hole surgery American Academy of

Ophthalmology, 2010

137. R. Radhakrishnan, S. Balaiya, V.S. Brar, R.K. Murthy, K.V. Chalam. Aqueous VEGF Levels in Patients

Treated With Bevacizumab for Central Serous Chorioretinopathy Proceedings of American Society

of Retina Specialists, 2010

138. R. Radhakrishnan, R. Keshavamurthy, S. Gupta, KV Chalam. Comparative (Contact Vs Noncontact)

Evaluation of Utility of Optiflex in Wide-Angle Vitreoretinal Surgery Proceedings of American Society

of Retina Specialists, 2010

30 10/10/11

139. K.V.Chalam, MD, PhD, R.K. Murthy MD ,S. Balaiya Ph.D, R. Malyapa MD, PhD. Evaluation of

Differential Sensitivity of Retinal Ganglion Cells and Choroidal Endothelial Cells to Proton Beam

Radiation: A Model for the study of AMD Proceedings of American Society of Retina Specialists,

2010

140. R Keshavamurthy MD, KV Chalam MD, S Grover MD . Asymptomatic temporal inner retinal thinning

on Spectral-domain Optical Coherence Tomography: An indicator of peripheral ischemia in

proliferative sickle cell retinopathy Proceedings of American Society of Retina Specialists, 2010

141. S. Balaiya, R. Malyapa, K.V. Chalam. Proton Beam Radiation Selectively Destroys Proliferating

Chorodial Endothelial Cells and preserves Non-proliferating Retinal Pigment Epithelial Cells: A Model

for Choroidal Neovascular Membrane. Association for Research in Vision and Ophthalmology, Ft.

Lauderdale, FL, 2010

142. K. V. Chalam, S. Balaiya, R. Keshavamurthy, Brar VS. Comparative in vitro Safety Analysis of Vital

Dyes for Chromovitrectomy-Indocyanine Green, Infracyanine Green, Brilliant Blue Green and

Bromophenol Blue. Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL,

2010

143. J.D. Edwards, S. Balaiya, K.V. Chalam. Estimation of TNF-α Concentration In Aqueous Humor

Samples of Normal Human Subjects With Bead Based Immuno Assay. Association for Research in

Vision and Ophthalmology, Ft. Lauderdale, FL, 2010

144. S. Grover, S. Balaiya, V.S. Brar, K.V. Chalam. Measurement of Aqueous VEGF levels in Patients with

Retinal Diseases is Superior and Accurate in Fresh Than Stored Samples. Association for Research

in Vision and Ophthalmology, Ft. Lauderdale, FL, 2010

145. R. Radhakrishnan, S. Balaiya, V.S. Brar, R.K. Murthy, S. Grover, K.V. Chalam. Aqueous VEGF levels

after Intravitreal Ranibizumab for Diabetic Macular Edema. Association for Research in Vision and

Ophthalmology, Ft. Lauderdale, FL, 2010

146. D.W. Hwang, S. Balaiya, R. Malyapa, K.V. Chalam. Effect of Proton Beam Radiation on The Survival

of Two Different Ocular Cell-colonies: Fine Tuning Treatment of Choroidal Neovascularization with

Radiation. Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2010

147. V.S. Brar, R. Keshavamurthy, S. Balaiya, K.V. Chalam. Aqueous Vascular Endothelial Growth Factor

Levels in Exudative Age Related Macular Degeneration after Combination Treatment with

Bevacizumab and Photodynamic Therapy. Association for Research in Vision and


148. C.M. Cutler Peck, S. Grover Functional Changes Correlate with Structural Changes in North Carolina

Macular Dystrophy Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL,

2010

31 10/10/11

149. R. Cappelli, K.V. Chalam, S. Grover. Spectral-Domain Optical Coherence Tomography and Fundus

Autofluorescence Findings in Patients with Pattern Dystrophy Association for Research in Vision

and Ophthalmology, Ft. Lauderdale, FL, 2010

150. R. Keshavamurthy, V.S. Brar, S.K. Gupta, S. Grover, K.V. Chalam. Foveal Microstructure As

Delineated By Spectral-domain OCT Accurately Predicts Functional Outcome On Microperimetry

After Macular Hole Surgery Association for Research in Vision and Ophthalmology, Ft.

Lauderdale, FL, 2010

151. Rajesh K Sharma, Anna T Rogojina, K.V. Chalam. Anti-VEGF therapy normalizes pathological

intraocular environment in neovascular conditions Association for Research in Vision and


152. A.T. Kelmenson, R.K. Murthy, S. Grover. Functional Changes Correlate With Structural Changes in

Patients with Stargardt's Disease Using SDOCT, Autofluorescence, and Micro-perimetry Association

for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2010

153. R Keshavamurthy MD, KV Chalam MD, S Grover MD. Foveal Structural and Functional Findings in

Patients with Pattern Dystrophy Proceedings of American Society of Retina Specialists, 2010

154. Shailesh K Gupta, Ravi Keshavamurthy, Sandeep Grover, K V Chalam. Concurrent Pars Plana Vitrectomy Performed to Remove Intravitreal Lens Fragment After Phacoemulsification Eliminates the Risk of Retinal Detachment. American Academy of Ophthalmology, 2009.

155. Sandeep Grover, Deepak Paul Edward, Erica P Dixon, K V Chalam. Live webcast lectures: an

innovative tool in ophthalmology resident education American Academy of Ophthalmology, 2009 156. VS Brar, S Balaiya, RK Murthy, KV Chalam “An in vitro effect of UV-induced phototoxicity on retinal

cells” ASIA Association of Research in vision and ophthalmology, Hyderabad, India, 2009

157. S. Balaiya, R. Malyapa, N. Mendenhall, KV Chalam. “An effect of proton radiotherapy on cultured

retinal cells” ASIA Association of Research in vision and ophthalmology, Hyderabad, India, 2009

158. R Keshavamurthy, S Grover, KV Chalam. “Difference In Macular Thickness As Measured By Time-

domain OCT (Stratus) And Spectral-domain OCT (Spectralis)” ASIA Association of Research in

vision and ophthalmology, Hyderabad, India, 2009

159. Keshavamurthy R, Balaiya S, Chalam KV. Comparative Effect of Indocyanine and Infracyanine Green

on Cultured Retinal Ganglion Cells. Association for Research in Vision and Ophthalmology May

3-7, 2009, Ft. Lauderdale, Florida.

32 10/10/11

160. Sharma RK, Roberts ML, Chalam KV. Protective Effect of Preconditioning on Oxidative Stress

Induced Cell Death in RGC Cells. Association for Research in Vision and Ophthalmology May 3-

7, 2009, Ft. Lauderdale, Florida.

161. Patel MC, Balaiya Mehanathan S, Chalam KV. Ultraviolet Induced Oxidative Stress on Retinal

Ganglion and Pigment Epithelial Cells. Association for Research in Vision and Ophthalmology

May 3-7, 2009, Ft. Lauderdale, Florida.

162. Brar VS, Sharma RK, Keshavamurthy R, Chalam KV. Vascular Endothelial Growth Factor Protects

Against Oxidative Stress in Differentiated Retinal Ganglion Cells. Association for Research in

Vision and Ophthalmology May 3-7, 2009, Ft. Lauderdale, Florida.

163. Kelmenson AT, Keshavamurthy R, Brar VS, Hwang DW, Chalam KV, Grover S. Comparative

Difference in Macular Thickness as Measured Between Spectral-Domain OCT (Spectralis) and Time-

Domain OCT (Stratus). Association for Research in Vision and Ophthalmology May 3-7, 2009,

Ft. Lauderdale, Florida.

164. Hwang DW, Keshavamurthy R, Brar VS, Chalam KV, Grover S. Establishment of Macular Thickness

in Normal Eyes With Spectral-Domain Spectralis Optical Coherence Tomography. Association for

Research in Vision and Ophthalmology May 3-7, 2009, Ft. Lauderdale, Florida.

165. Roberts ML, Sharma RK, Gupta SK, Chalam KV. Proliferating Retinal Cells Produce Growth Factors

that Create Pro-Proliferation Environment. Association for Research in Vision and Ophthalmology

May 3-7, 2009, Ft. Lauderdale, Florida.

166. Cappelli R, Keshavamurthy R, Brar VS, Chalam KV, Grover S. Evaluation of Thickness of Individual

Layers of the Retina With Spectral-domain OCT for Establishment of Normal Clinical Values.

Association for Research in Vision and Ophthalmology May 3-7, 2009, Ft. Lauderdale, Florida.

167. Storm L, Keshavamurthy R, Brar V, Chalam KV, Grover S. Evaluation of Optic Nerve Head Drusen

Using Spectral-domain OCT (Spectralis). Association for Research in Vision and Ophthalmology

May 3-7, 2009, Ft. Lauderdale, Florida

168. Chalam KV, Balaiya Mehanathan S, Keshavamurthy R. Evaluation of Differential Sensitivity of Retinal

and Choroidal Cells to Proton Beam Radiation: A Model for Age Related Macular Degeneration.

Association for Research in Vision and Ophthalmology May 3-7, 2009, Ft. Lauderdale, Florida.

169. Balaiya Mehanathan S, Malyapa R, Mendenhall N, Chalam KV. Proton Radiation Predominantly

Destroys Choroidal Endothelial Cells While Preserving Retinal Ganglion Cells. Association for

Research in Vision and Ophthalmology May 3-7, 2009, Ft. Lauderdale, Florida.

170. RK Murthy, S Balaiya, VS Brar, KV Chalam. “Effects of Indocyanine green on cultured retinal ganglion

cells: An in vitro study” International society of ocular toxicology , Philadelphia, PA, 2008

33 10/10/11

171. ML Roberts, RK Sharma,VS Brar, KV Chalam. “Effect of bevacizumab on viability of human corneal

cell lines” International society of ocular toxicology, Philadelphia, PA, 2008

172. S.Balaiya, R Malyapa, KV Chalam. “In vitro study of proton beam radiation toxicity on retinal cells”

International society of ocular toxicology, Philadelphia, PA, 2008

173. VS Brar, S Balaiya, RK Murthy, KV Chalam, “An in vitro effect of UV-induced phototoxicity on retinal

cells” International society of ocular toxicology, Philadelphia, PA, 2008

174. Chalam KV, Gupta SK, Brar VS, Murthy RK. Evaluation of Ultra wide angle „ora-ora‟ high refractive

index self-stabilizing Wide-angle Contact lens for Vitreous Surgery. American Society of Retina

Specialists October 11–15, 2008 Maui, Hawaii.

175. Grover S, Keshavamurthy R, Brar VS, Chalam KV. Normative data for macular thickness by spectral-

domain OCT (Spectralis). American Society of Retina Specialists October 11–15, 2008 Maui,

Hawaii.

176. Brar VS, Sharma RK, Chalam KV. In vitro toxicity of bevacizumab (Avastin®) in retinal ganglion

and choroidal endothelial cell. American Society of Retina Specialists October 11–15, 2008 Maui,

Hawaii.

177. Gupta SK, Brar VS, Keshavamurthy R, Sharma RK, Chalam KV. Evaluation of aqueous VEGF levels after intravitreal bevacizumab for retinal vein occlusion. American Society of Retina Specialists October 11–15, 2008 Maui, Hawaii.

178. Murthy RK, Chalam KV. “Quality of Life Measured by the 25-Item NEI Visual Function Questionnaire Correlates Accurately With Severity of Diabetic Macular Edema” American Academy of Ophthalmology, Atlanta, 2008.

179. Chalam KV, Murthy RK, Gupta SK. “ Inner Segment/Outer Segment Changes on Ultrahigh-Resolution Spectral OCT Accurately Predict Visual Acuity Recovery After macular hole repair” American Academy of Ophthalmology, Atlanta, 2008.

180. Grover S, Murthy RK, Brar S, Chalam KV. Macular thickness in normal subjects by spectral-domain OCT (Spectralis)”. American Academy of Ophthalmology, Atlanta, 2008.

181. Chalam KV, Gupta SK. Aqueous Vascular Endothelial Growth Factor Levels Accurately Correlate With Regression of Neovascularization After Avastin Administration in Exudative Macular Degeneration. American Academy of Ophthalmology, Atlanta, 2008.

182. V.S. Brar, R.K. Sharma, K.V. Chalam, “Assessment of Cytotoxicity of Bevacizumab on Choroidal Endothelial, Retinal Ganglion, and Retinal Pigment Epithelial Cells” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2008.

183. R.K. Sharma, A. Rogojina, K.V. Chalam, “Use of Multiplex Technology for Analyzing Human Aqueous

Samples for a Battery of Analytes” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2008.

34 10/10/11

184. M.C. Patel, V. Brar, S. Gupta, K.V. Chalam, Evaluation of Second Generation Modified Portable

Digital Camera for Documentation of Retinal Pathology” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2008.

185. M.G. Roberts, R.K. Sharma, C.N. Nagineni, A. Grover, K.V. Chalam, “ Evaluation of Bevacizumab

Cytotoxicity on Human Corneal Cell Lines” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2008.

186. S. Grover, W. Phillips, J. Sifrit, A. Dominik, A. Shtjefni, K. Chalam “Perifoveal Retinal Function in Patients With Macular Drusen” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2008.

187. C.N. Nagineni, V.K. Kommineni, K.V. Chalam, B. Detrick, J.J. Hooks, “Interleukin-11 Expression by

Human Retinal and Corneal Cells: Regulation by IL-1, TNF-α, IFN-γ and TGF-β” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2008

188. K.V. Chalam, S. Grover, S. Gupta, V.S. Brar, R.K. Sharma, “Evaluation of Vascular Endotheilal

Growth Factor Levels After Intravitreal Bevacizumab in Retinal Disorders” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2008

189. S.N. Syed, S. Gupta, V.S. Brar, S. Grover, K.V. Chalam ”Improvement of Visual Acuity and Resolution

of Macular Edema Associated With Chronic Disciform Scars After Intravitreal Bevacizumab” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2008

190. S.K. Gupta, V.S. Brar, K. Chalam, “Comparative (Contact vs. Noncontact) Evaluation of Utility of

Optiflex Assistant System in Wide Angle Panoramic Vitreoretinal Surgery” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2008

191. K.V. Chalam, Shailesh K Gupta, Sandeep Grover. “Portable Digital Camera is as effective as

traditional nonmydriatic fundus camera in screening for AMD”, American Academy of Ophthalmology, New Orleans, 2008.

192. K.V. Chalam, Shailesh K Gupta, Sandeep Grover, Sadiq N Syed, “Birth weight alone is the most

predictable and reliable criteria in screening for ROP” American Academy of Ophthalmology, New Orleans, 2008.

193. K.V. Chalam, Shailesh K Gupta, Swati Agarwal, Sandeep Grover, “Human Aqueous Vascular

Endothelial Growth Factor levels accurately predict regression of Iris neovascularization after Avastin administration in neovascular glaucoma” American Academy of Ophthalmology, New Orleans, 2008.

194. K.V.Chalam, Shailesh K Gupta, “Comparative analysis of optical coherence tomography and retinal

angiography in eyes treated with intravitreal bevacizumab for neovascular AMD” Proceedings of American Society of Retina Specialists,2008

35 10/10/11

195. Shailesh K Gupta, K.V. Chalam, “Microperimetry findings in patients treated with intraviteal avastin for exudative age-related macular degeneration” Proceedings of American Society of Retina Specialists,2008

196. K.V. Chalam, Shailesh K Gupta, “Evaluation of touch sensitive optiflex system as surgical assistant in

vitreoretinal surgery” Proceedings of American Society of Retina Specialists,2008 197. Shailesh K Gupta, K. V. Chalam, “Evaluation of simultaneous placement of a foldable IOL (FIOL) in

vitreoretinal surgery combined with phakoemulsification surgery” Proceedings of American Society of Retina Specialists, 2008

198. K. V. Chalam, Farhana Syed, Jason Sifrit, Sadiq Syed, Sandeep Grover, Shailesh Gupta “Evaluation

of Modified Portable Digital Camera as a Screening Tool in Retinal Disorders” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2007. Page 129

199. Swati Agarwal, Rajesh Sharma, K V Chalam, Tina Tillis, “Evaluation of Nerve growth factor levels (NGF) in Aqueous of Primary Open Angle Glaucoma” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2007. Page 212

200. Sandeep Grover, Swati Agarwal, Shailesh Gupta, K.V. Chalam, “Role of Intracameral Avastin in Neovascularization of Iris Secondary to Retinal Diseases” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2007. Page 246

201. C.N. Nagineni, V.K. Kommineni, K.V. Chalam, R.Raju, B.Detrick, J.J. Hooks “TGF-β Upregulates Extracellular Matrix Protein Anosmin (KAL-1) Expression in Human Retinal Pigment Epithelial Cells” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2007. Page 126

202. Manish Patel, Swati Agarwal, Shailesh Gupta, K.V. Chalam “Evaluation of OptiFlex as Surgical Assistant in Wide-angle contact lens assisted Vitreoretinal Surgery” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2007. Page 110

203. William Phillips, Farhana Syed, Shailesh Gupta, Sandeep Grover, K.V. Chalam “Evaluation of Modified Retinopathy of Prematurity (ROP) Using Birth-Weight (BW) as Sole Inclusion Criterion” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2007. Page 198

204. Lorene F. Ward, Rajesh K. Sharma and K.V. Chalam “Induction of Stem Cell Markers in Non-Stem Cell Lines With Growth Factor Stimulation” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2007 Page 199

205. Farhana Syed, K.V. Chalam, R.C. Tripathi, Brenda J. Tripathi “Ciliary Epithelium is an Extraretinal Source of Vascular Endothelial Growth Factor (VEGF) in Neovascular Glaucoma” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2007 Page 284

206. S. Gupta, S.Grover, W. Phillips, K.V. Chalam “Microperimetry vs. Humphrey Visual Field in the Evaluation of Toxic Maculopathy” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2007 Page 201

36 10/10/11

207. S.N. Syed, K.V. Chalam, S.K. Gupta, S. Grover, F. Syed, W. Phillips “Intravitreal Bevacizumab for the Treatment of Central Retinal Vein Occlusion” Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2007. Page 16

208. Chalam KV, Grover S, Beaver H, Tsai J. Emerging Biological and Pharmacological Therapies for Ocular Diseases: Highlights of BCSC 2. American Academy of Ophthalmology, Las Vegas, 2006

209. Chalam KV, Gupta S, Grover S, Agarwal S. Intracameral Avastin dramatically resolves Iris Neovascularization and Reverses Neovascular glaucoma. American Academy of Ophthalmology, Las Vegas, 2006

210. Chalam KV, Gupta S, Grover S, Agarwal S. Modified Portable Digital Camera as effective as Traditional Nonmydriatic Fundus Camera in screening of Diabetic Retinopathy. American Academy of Ophthalmology, Las Vegas, 2006

211. Chalam KV, Gupta S, Grover S, Agarwal S. Evaluation of comparative Efficacy of Topical Tetravisc vs.Lidocaine Jelly in cataract surgery. American Academy of Ophthalmology, Las Vegas, 2006

212. Chalam KV, Agarwal S, Gupta SK . Evaluation of portable digital camera for screening of Diabetic retinopathy in primary care and satellite clinics. Proceedings of American Society of Retina Specialists, 2006. p140

213. Chalam KV, Gupta S, Grover S, Agarwal S. Evaluation of Relationship between VEGF levels and Age Related Macular Degeneration. Proceedings of American Society of Retina Specialists, 2006. p140

214. Agarwal S, Grover S, Chalam KV, Gupta S. Effect of Intracameral Bevacizumab on Neovascularization of the Iris. Proceedings of American Society of Retina Specialists, 2006. p140

215. Agarwal S, Gupta S, Grover S,Chalam KV. Correlation of Optical Coherance Tomography and Retinal angiography in Patients treated with Bevacizumab for Choroidal Neovascular Membrane. Proceedings of American Society of Retina Specialists, 2006. p140

216. K. V. Chalam, William.W.Phillips, Swati Agarwal, Sandeep Grover, Shailesh Gupta “Evaluation of toxic effects of Ultra-violetB induced Apoptosis in Retinal Ganglion Cells.” International Society of Ocular Toxicology, Germany, 2006

217. William.W.Phillips, Kakarla. V. Chalam, Swati Agarwal, Sandeep Grover, Shailesh Gupta “Effects of

Indocyanine Green on Cultured Rat Retinal Ganglion Cells in Vitro.” International Society of Ocular Toxicology, Germany, 2006

218. Patel M, Sifrit JA, Agarwal S, Gupta SK, Chalam KV. “Autoclavable Wide-Angle Multi-lens Contact

Lens for Vitreoretinal evaluation”. Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2006. 2006;46:ARVO E-Abstract 3641

219. Sifrit JA, Patel M, Agarwal S, Gupta SK, Chalam KV. “ Evaluation of Fixation Patterns in Macular Diseases with Liquid Crystal Display Fundus Microperimetry”. Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2006. 2006;46:ARVO E-Abstract 3625

37 10/10/11

220. Chalam KV, Ward L, Agarwal S, Tripathi B, Tripathi R. “Evaluation and Comparison of Vitreal Nerve Growth Levels in various Retinal diseases”. Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2006. 2006;46:ARVO E-Abstract 2775

221. Ward L, Chalam KV “Evaluation of Growth Factors in Human Neural Stem and Retinal Progenitor Cell Conditioned media”. Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2006. 2006;46:ARVO E-Abstract 3687

222. Agarwal S, Agarwal N, Tripathi B, Tripathi R, Chalam KV. “Influence of Ciliary Neurotrophic factor (CNTF) on Apoptotic Retinal Ganglion Cell Death Induced by Glutamate Excitoxicity”. Association for Research in Vision and Ophthalmology, Ft. Lauderdale, FL, 2006. 2006;46:ARVO E-Abstract 3266

223. Chalam KV. Anti VEGF therapy for AMD. Proceedings of All India Ophthalmic Society, Bhopal, India, 2006, p62

224. Chalam KV. MP-1 microperimetry in Retinal disorders. Proceedings of All India Ophthalmic Society, Bhopal, India, 2006, p67

225. Chalam KV. “Screening with birth weight < 1250 (g) identifies all high risk retinopathy of prematurity for early treatment and avoids unnecessary examinations” Proceedings of All India Ophthalmic Society, Bhopal, India, 2006, p352

226. Shah GY, Chalam KV. Inmnovative surgical approach to anterior vitreoretinal pathology – instrumentation and its uses. Proceedings of American Society of Retina Specialists, 2005. p140

227. Chalam KV, Shah GY. A novel reuseable instrument system for creating 25-gauge sclerotomies in suturelss pars plana vitrectomies. Proceedings of American Society of Retina Specialists, 2005.p139

228. Gupta SK, Chalam KV. Quality of life in diabetic retinopathy as measured by the 23-item NEI and TTO utility values. Proceedings of American Society of Retina Specialists, 2005.p141

229. Lin SJ, Chalam KV. Comparative evaluation of toxic effects of indocyanine green and tryphan blue on survival or retinal ganglion cells. Proceedings of American Society of Retina Specialists, 2005. p145

230. Chalam KV. Determination of patterns of foveal fixation in age related macular degeneration with fundus microperimetry (LCDMP-1). Proceedings of American Society of Retina Specialists, 2005.p149

231. Shah GY, Chalam KV. Evaluation of web based annotation of ophthalmic images for multi-center clinical trials. Proceedings of American Society of Retina Specialists, 2005.p158

232. Lin SJ, Chalam KV. Birthweight 1250 grams(g) identifies all high risk Retinopathy of Prematurity (ROP) for early treatment. Proceedings of American Society of Retina Specialists, 2005. p160

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233. Gupta SK, Chalam KV. Evaluation of simultaneous placement of foldable IOLs in vitreoretinal surgery combined with bimanual microincisional phacoemulsification surgery. Proceedings of American Society of Retina Specialists, 2005.p163

234. Shah GY, Chalam KV. Successful management of optic disc melanocytoma associated choroidal neovascularization with photodynamic therapy (PDT). Proceedings of American Society of Retina Specialists, 2005.p169

235. Lin DT, Pakalnis VA, Tripathi RC, Yee SB, Chalam KV. Spontaneous medial wall fracture caused by nose blowing and persisting as proptosis.Evaluation of Screening Criteria for Retinopathy of Prematurity. American Journal of Ophthalmology 139(3): S24, 2005

236. Gupta SK, Chalam KV. “Screening with birth weight < 1250 (g) identifies all high risk retinopathy of prematurity for early treatment and avoids unnecessary examinations” American Academy of Ophthalmology, Chicago, 2005

237. Chalam KV, Shah GY, Agarwal S, Gupta SK. “25 g vs. 20 g: Ultrasound Biomicroscopic Evaluation of Vitreous Incarceration in Sclerotomies after Pars Plana Vitrectomy ” American Academy of Ophthalmology, Chicago, 2005

238. Gupta SK, Agarwal S, Chalam KV. “Evaluation of Concurrent Sutureless 25g Vitreoretinal Surgery & Bimanual Microincisional Phakoemulsification with Placement of Foldable IOLs” American Academy of Ophthalmology, Chicago, 2005

239. Shah GY, Gupat SK, Agarw

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