KORSCH Tablet Compression Technology. The Ultimate Research Tool XL 100 Pro Tablet Press.

KORSCH Tablet Compression Technology

The Ultimate Research Tool

XL 100 Pro Tablet Press

XL100 Presentation Outline

General Specifications System Flexibility Control System Data Acquisition and Analysis Technical Support Services Industry References System Advantages


General Specifications

XL100 Specifications

Fully GMP Compliant Exchangeable Turret Capability

8 Station, IPT or EURO D Tools 10 Station, IPT or EURO B Tools 12 Station, IPT or EURO BB Tools

10 kN Precompression Force 60 kN Main Compression Force 120 RPM Press Speed Capability



Stainless Steel Execution Frequency Drive on Main Motor Open Gravity Feed Frame Variable Speed Power Feed Frame Sealed Compression Zone Quick Disconnect Design Noise Dampening System



Handwheel Adjustments Tablet Weight Tablet Thickness

Allen-Bradley PLC Controls Basic Parameters Machine Diagnostics

Color Touch Screen



Machine Instrumentation Precompression Force Main Compression Force Tablet Ejection Force

Press Force Control Option Automatic Weight Control Single Tablet Rejection

Tablet Sampling Station Option


Carrier Plate Design Compression Zone Fully

Isolated from Machine Frame and Head Piece

Extremely QUIET Operation

Noise Dampening Design


Flexibility

Exchangeable Turret

Exchangeable Turret

Permits the Development of ANY SIZE Tablet on a Single Machine

Permits Fast Change Capability for Extreme Efficiency Offers Opportunity to Dedicate Turrets for Specific

Actives for Potent Applications


XL100 Turret Configurations

Number ofStations

Press ToolSpec

Max TabletDiameter

8 D 25 mm10 B 16 mm12 BB 13 mm


Turret Removal


Turret Lift/Transport Unit


XL100 Turret Removal


Mounted to Carrier Plate 60 kN Press Force

Capability Pivots to Permit Turret

Removal

Main Compression Assembly


Main Compression Assembly


Flexibility

Power Feeder and Gravity Feeder

Variable Speed Power Feed Frame

Mounted on Fixed Support Table

Preset Clearance to Die Table

Quick Disconnects for Easy Removal and Cleaning

Power Feeder


Power Feeder


Gravity Feeder


Flexibility

Operation with Minimal Material Quantities

Full Functionality with Any Number of Reduced Tools

Requires Only Installation of Blank Dies

Reduced Tools


Minimal Quantities Power Feeder

XL100 Offers Low Level Over-Ride Capability Low Speed Capability to 5 RPM Choice of Feeder Paddles

Rectangular Cross Section Round Cross Section

Permits Use with < 1kg


Minimal Quantities Gravity Feeder

Permits Operation With Extremely Minimal Quantities (< 50 grams)

Manual Feeding Option for Single Punch Utilization


Flexibility

Fast Set-Up and Changeover

Innovative Design Eliminates Corner Columns

Complete Access to Compression Zone

Smooth Surfaces and Quick Disconnects

Compression Zone


Complete Disassembly in 10-15 Minutes

Complete Turret Removal in 10 Minutes

Fast Change Capability


Ergonomic Placement Permits Fast Press Tool

Installation and Removal Interlock for Safe

Operation

Manual Handwheel for Turret Rotation


Flexibility

Full Instrumentation

Instrumentation

Main Compression Force Precompression Force Tablet Ejection Force

Segmented Cam


Flexibility

Caster Base for Portability

Stainless Steel Base Locking Casters Permits Full Portability Leveling Footpads

Included

XL100 on Caster Base


XL100 Caster Base


Leveling Footpads


Flexibility

Control for Clinical Batch Production

Optional Press Force Control with Single Tablet Rejection

Offers Production Scale Process Control

Clinical Batch Production


3-Channel Chute Good Tablets Bad Tablets Sample Tablets

Optional Feedback Control Based on Actual Tablet Weight

Clinical Batch Production


Flexibility

Product Containment

IDEAL for Product Containment Applications

Enables the Development of High Potency Compounds

Isolator Retrofit Kit Available

Product Containment


XL100 Isolator Mock-Up


Retrofit Isolator Kit


Retrofit Isolator Kit

Dual Hepa Filters on Air Inlet/Outlet with Safe Change 270 mm RTP to Remove Machine Parts for Cleaning Portable Ventilation/Filtration Skid for Negative Pressure

Control Containment Valve Selection for Any OEL Requirement


Flexibility

Wash-in-Place Capability

WIP Capability

Compression Zone Components Upgraded to 316L Stainless Steel

Fixed Spray Nozzle in Feed Pipe to Clean Feed Pipe and Feeder

Manual Spray Head for Compression Zone, Manipulated Via Glove Port

Permits Simple Rinse, or Detergent Wash


XL100 WipCon


XL100 Control System

Allen-Bradley PLC Platform


User-Friendly Operator Interface

Minimum Number of Control Screens for EASE of Use

Displays Basic Machine Controls and Press Faults

Touch Screen Interface


Login Capability


Password Administration


User Administration


User Profile


Access Authorization


Main Screen


Service Screen


Press Force Control


Additional Forces


Press Force Trending


Single Forces Screen


Reduced Tools


Calibration Screen


Calibrate Press Speed


Calibrate Feeder Speed


Calibrate Amplifiers


Calibrate Dosing


Single Tablet Rejection


Single Sorting Limits


Tablet Rejection Log


Magnesium Stearate Spray System (Optional)


Language Selection


Report Printing

All Control Screens Single Press Forces Machine Parameters

Permits Repeatable Machine Set-Up Between Machine and Sites


XL100 PRO - Optional WonderWare Platform

General Machine Controls


User LOGIN with PASSWORD


EVENT LOG


PRESS FORCE Limits


SINGLE FORCES


REJECT LOG


Tablet Sampling Protocol


Tablet Data Entry


PMA-3 Data Acquisition System

Stainless Steel Cabinet Caster Base Windows Platform Real-Time Display of

Force Parameters Data Collection and

Analysis with Storage and Export of Data

21 CFR Part 11 Compliant

KORSCH PharmaResearch® Data Acquisition System


PharmaResearch® Amplifier Rack


PharmaResearch® Data Collection


PharmaResearch® Data Analysis


PharmaResearch® Display Single Forces


PharmaResearch® Data Analysis


PharmaResearch® Main Screen


Data Integrity

All Reports in Secure PDF Format Burned to CD Option to Direct Data Reports to Central Network


Technical Support Services


Equipment Validation Support IQ/CQ/OQ Documentation Execution of Protocols On-Site

Training Certification Program Training Documentation

PM and Calibration Service Complete Spare Parts Inventory


XL100 Advantages

Extreme Flexibility

Exchangeable Turret Power Feeder/Gravity Feeder Use with Minimal Material Quantities Fast Set-Up and Changeover Full Instrumentation Caster Base for Portability Control for Clinical Batch Production Product Containment Capability Wash-In-Place Capability


User-Friendly Controls

Simple Monitoring Press Force Control with Single Tablet Rejection Comprehensive Data Collection and Analysis



Turnkey Validation Program Comprehensive Training Program


We Look Forward To A Working Partnership in the Future ...

KORSCH XL100 Tablet Press


KORSCH America Inc.18 Bristol DriveSouth Easton, MA 02375Phone 508-238-9080Fax 508-238-9487www.korschamerica.com

© KORSCH AG13509 Berlin

Germany

Thank You!

KORSCH Tablet Compression Technology. The Ultimate Research Tool XL 100 Pro Tablet Press.

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