Kidney Lecture 1
Transcript of Kidney Lecture 1
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KIDNEY 1 LecturePhotos: Baxe and Tony
And Google
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Dear Student,
Here are kidneys donated by your
generous colleagues, Baxe and Tony. Theysaved your life from end-stage pathopathy.
Maybe, you should save others too.
http://hopetransplant.tripod.com/about.htm
http://www.facebook.com/group.php?gid=286413899935
http://www.facebook.com/l.php?u=http%3A%2F%2Fhopetransplant.tripod.com%2Fabout.htm&h=04776http://www.facebook.com/group.php?gid=286413899935http://www.facebook.com/group.php?gid=286413899935http://www.facebook.com/l.php?u=http%3A%2F%2Fhopetransplant.tripod.com%2Fabout.htm&h=04776 -
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Components of the normal Kidney
1. Blood Vessels
2. Glomeruli
3. Tubules
4. Interstitium
BGTIn
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Nephrotic Syndrome(Acute Proliferative Glomerulonephritis)
ACUTE PROLIFERATIVE GN
Post-Streptococcal Infection
Post-Infectious
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Post-Streptococcal GN
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Juxys PostStrep HUMP
Only seen under ELECTRON MX
and by Juxys wonder eyes
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Art Appreciation Section:Explain to your seatmate what the hell this is
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RPGN(Rapidly progressive glomerulonephritis)
BREAKS IN THE GBM
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RPGN - Crescents
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RPGN - IF
A BA. LINEAR Anti-GBM Type 1
B. GRANULAR Post- Infectious
* NONE Pauci- immune
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Membranous Glormerulopathy
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MOST COMMON CAUSE OF
NEPHROTIC SYNDROME IN ADULTS
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ELECTRON MX:
Effacement of foot processes
Subepithelial electron-dense deposits
Basement membrane materials laid down between deposits
(SPIKES)
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SPIKES
MEMBRANOUS GLOMERULOPATHY
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Membranous
Glomerulopathy
Electron
Mx
changes
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Minimal Change Disease
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MOST COMMON CAUSE OF
NEPHROTIC SYNDROME IN CHILDREN
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Uniform and diffuse
Effacement of podocytes
Or foot processes
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Minimal Change Disease
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FSGS
(Focal Segmental Glomerulosclerosis)
PAS STAIN
A. LPO Sclerosis in 1 of the 3 glomeruli (Blue arrow)
B. HPO Hyaline insudation and lipid (small vacuoles) in sclerotic area
WORDS FOR DUMMIES:
insudation /insudation/ (-soo-dashun) the accumulation, as in the kidney,
of substances derived from the blood.
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FSGS Hallmark
Degeneration and disruption of VISCERAL
EPITHELIAL CELLS
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Membranoproliferative GN (MPGN)
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Type 1 MPGN
- subendothelialdeposits
Type 2 MPGN
(Dense-Deposit
Disease)
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ISOLATED URINARY ABNORMALITIES
I hate youWhoever made
The champion
BERGER ad.You made me believe.
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ISOLATED URINARY ABNORMALITIESIgA Nephropathy (BERGER DISEASE)
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IgA deposits in Mesangium
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BERGER DISEASE
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Chronic glomerulonephritis (CGN)
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chronic glomerulonephritis
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Hyalinzation of glomerulus
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DM: Nodular Glomerulosclerosis
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FOR YOUR ADDED IMPT INFO FOR THIS TOPIC
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Juxys Body Series:
Juxys Genital System
Juxys Boobies
Juxys Endocrine Syste
PLS POST AT THE BATCH 2013 FB GROUP.
Thats if you think it is important and youre not
Planning to sabotage the entire batch just cuz
Youre the only one WHO KNOWS! Britney!