Key Stage 4 Magnetic Resonance Imaging Watching the brain at work .

10
Key Stage 4 Magnetic Resonance Imaging Watching the brain at work www.oxfordsparks.net/mri

Transcript of Key Stage 4 Magnetic Resonance Imaging Watching the brain at work .

Page 1: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work .

Key Stage 4

Magnetic Resonance Imaging

Watching the brain at work

www.oxfordsparks.net/mri

Page 2: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work .

If you wiggle your fingers……there is more activity in these brain

areas.

www.oxfordsparks.net/mri

Page 3: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work .

These areas of the brain need more oxygen…

activation statebaseline

More blood flow

More oxygenated blood

Less distortion of magnetic field

More fMRI signal

…which the blood delivers

www.oxfordsparks.net/mri

Page 4: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work .

An experiment

rest move rest move rest move restTask FMRI signal

time

These areas of the brain are active

during movement, but not rest.

www.oxfordsparks.net/mri

Page 5: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work .

The FMRI scanner looks at one brain ‘slice’ at a time…

www.oxfordsparks.net/mri

Page 6: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work .

You can locate an area of the brain using X, Y, and Z co-ordinates.

The image is divided into

voxels. Voxels are 3D pixels.

www.oxfordsparks.net/mri

Page 7: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work .

The trace shows that this voxel is relevant to the task.

www.oxfordsparks.net/mri

Page 8: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work .

Colour Vision• FMRI does not give an

absolute measure, so you need to look at signal change.

• To isolate one brain function, compare the condition you are investigating to a control condition.

www.oxfordsparks.net/mri

Page 9: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work .

The subtraction approach: vision

View grey

stimuli (control)

View colourstimuli

grey colour grey colour grey colour greyTask:fMRI signal

time

www.oxfordsparks.net/mri

Page 10: Key Stage 4 Magnetic Resonance Imaging Watching the brain at work .

The subtraction approach: vision

- =

www.oxfordsparks.net/mri