Kevin Yocum Digestive System 2

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    Chapter 25

    The Digestive System

    Kevin Yocum

    Fall 2013

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    Objectives for 25.4

    Describe the anatomy of the liver, gall

    bladder, bile duct, and pancreas.

    Describe the digestive secretions of

    the liver, gall bladder, and pancreas.

    Explain the hormonal regulation of theliver and pancreas.

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    The Liver

    Hepatic lobules Central vein

    Hepatic sinusoids

    Hepatic portal system

    Bile duct Hepatic ducts

    Cystic duct

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    Fig. 25.19

    Gross Anatomy of the Liver

    Notes: From Saladin 6thEd.

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    Notes: From Saladin 6thEd.

    Fig. 25.20Microscopic

    Anatomy of

    the Liver

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    The Gall Bladder

    Stores and concentrates bile

    Bile Bilirubin

    Urobilinogen

    Bile salts

    Lecithin Aid in fat digestion/absorption

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    The Pancreas

    Pancreatic juice

    Notes: From Saladin 6thEd.

    Fig. 25.23

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    Fig. 25.21

    Gross Anatomy of GB and Pancreas

    Notes: From Saladin 6thEd.

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    Regulation of Secretion

    Acetylcholine (ACh) Vagus and enteric nerves

    Pancreatic acini

    Cholecystokinin (CCK) Duodenal mucosa and proximal jejunum

    Intestinal fats

    Secretin Sodium bicarbonate

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    Checkpoint Questions

    The hepatic and cystic ducts converge

    to form the _______.

    The liver receives 70% of its blood from

    the ______________.

    _______ stimulates the liver andpancreatic ducts to secrete sodium

    bicarbonate.

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    Checkpoint Answers

    The hepatic and cystic ducts converge

    to form the bile duct.

    The liver receives 70% of its blood from

    the hepatic portal vein.

    Secretinstimulates the liver andpancreatic ducts to secrete sodium

    bicarbonate.

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    Objectives for 25.5

    Describe the complete anatomy of the

    small intestine.

    Differentiate between intestinal

    mucosa and stomach mucosa.

    Define contact digestion. Describe intestinal movements.

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    Gross Anatomy of the SI

    Duodenum

    Duodenojejunal flexure

    Jejunum

    Ileum Peyer patches

    Ileocecal junction

    Notes: From Saladin 6thEd.

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    Microanatomy of the SI

    Circular folds

    Villi

    Enterocytes and goblet cells

    Lacteal

    Intestinal crypts and intestinal juice

    Contact digestion Microvilli

    Brush border enzymes

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    Fig. 25.25

    Notes: From Saladin 6thEd.

    Intestinal

    Villi

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    Intestinal Motility

    Segmentation

    Peristalsis

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    Checkpoint Answers

    The second section of the small

    intestine is called thejejunum.

    Lipids are absorbed in the small

    intestines due to the presence of

    lacteals. Movement in which stationary ring-like

    constrictions appear at several places

    along the SI is called segmentation.

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    Objectives for 25.7

    Describe the anatomy of the large

    intestine.

    Contrast LI mucosa with SI mucosa. State the significance of intestinal

    bacteria.

    Discuss the types of colon

    contractions.

    Link neurology with defecation.

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    Microanatomy of LI

    Simple, columnar epithelium

    Anal canal Non-keratinized stratified squamous

    epithelium

    No circular folds or villi

    Crypts Deep

    Many goblet cells

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    Bacterial Flora and Gas

    Bacterial flora 800 species of bacterial flora in LI

    Digest cellulose, pectin, plant polysaccharides

    Gas

    Flatus 7-10 Liters, of which 500ml/day is expelled

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    Absorption and Motility

    12-24 hours from mouth to anus

    Reabsorption of water and electrolytes

    (ex: NaCl) 75% water

    25% solids Fiber, fat, proteins, salts, mucus

    Haustral contractions and mass

    movements

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    Defecation

    Intrinsic reflex Myenteric nerve plexus

    Parasympatheticreflex Spinal reflex

    Notes: From Saladin 6thEd.

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    Checkpoint Questions

    The first section of the large intestine is

    called the _____.

    Expelling of gas from the large intestine

    is known as ____.

    The defecation reflex that operatesentirely from the myenteric nerve plexus

    is the ___________________.

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    Checkpoint Answers

    The first section of the large intestine is

    called the cecum.

    Expelling of gas from the large intestine

    is known as flatus.

    The defecation reflex that operatesentirely from the myenteric nerve plexus

    is the intrinsic defecation reflex.

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    References

    Saladin, Kenneth (2012). Anatomy and

    Physiology, The Unity of Form and

    Function, Sixth Ed. New York, NY:McGraw-Hill.