KETOGENIC DIET : BODY WEIGHT MAINTENANCE EFFECTIVITY

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KETOGENIC DIET : BODY WEIGHT MAINTENANCE EFFECTIVITY Tutor 2

Transcript of KETOGENIC DIET : BODY WEIGHT MAINTENANCE EFFECTIVITY

KETOGENIC DIET : BODY WEIGHT MAINTENANCE EFFECTIVITY

Tutor 2

Outlines

1. Definition and History of Ketogenic Diet

2. Ketogenic Diet variations

3. Physiology of Ketosis

4. How To Diet In Ketogenic Way ?

5. Changes of body composition in KD

6. KD’s Effect related to Body Weight Loss

7. Conclusion

Definition of Ketogenic Diet

Ketogenic Diet Definition

Fat

Carbohydrate

Neal (2012)

History related to Ketogenic Diet

History related to Ketogenic Diet

5 BC

Fasting to

reduce seizure

1921

Ketogenic diet

was developed

by Wilder

1971

Ketogenic diet

medium chain

triglyceride

(MCT) was

invented

2017

Gupta et. al:

KD used to

treat diabetes,

obesity, and

other

metabolic

syndrome

Ketogenic Diet (KD) Variations

Classical KD

Medium Chain Triglyceride (MCT) KD

Low Glycemic Index Treatment (LGIT) KD

Modified Atkins Diet (MAD)

Physiology of ketosis

Keton Bodies

Products that resulted from free fat acid break down in the liver

Energy sources to substitute glucose

Reduce glucose production in the liver

Deliver message to other tissues in the body to use fat as

energy sources

Functions

(Source: Tortora, 2011)

Factors Affecting The Used of

Energy Sources

Quantity of nutrients

consumptionHormone

Liver Glycogen Enzyme

(McDonald, 1998)

HOW TO DIET IN KETOGENIC WAY ?

Warning !

Beta-oxidation defects

Diabetes Mellitus

Hypertension

Gastroesophageal reflux

Dysphagia

Medically diagnosed eating disorder

Allergies

Comparison of Types of Ketogenic Diet

Comparison

Classical

Ketogenic

Diet

MCT KetogenicDiet

LGIT KetogenicDiet

MAD

Fat Consumption 90%

73% (30-60% MCT)

60% 65%

ProteinConsumption 6% 10% 30% 35%

CarbsConsumption 4% 17% 10% 5%

Changes of body composition

Water

Water

Water

Glycogen Deuretic Effect

KD’s Effect related to Body Weight Loss

KD’s Effect related to Body Weight Loss

KD’s Effect related to Body Weight Loss

(Paoli, 2014)

Reduced lipogenesis, increased lipolysis

Higher metabolic efficiency

Higher cost of gluconeogenesis and protein thermic effect

Decreased appetite due to ketone bodies production

Thermic Effect

Fat

Carbohydrates

Protein

“The caloric cost of digesting and processing different macronutrients in your diet”

20-35%

5-15%

5%

(Paoli, 2014)

KD’s Effect related to Body Weight Loss

Gluconeogenesis cost

KD’s Effect related to Body Weight Loss

ghrelin

leptin

Appetite suppressed

Take-Home Messages

• Apart from weight loss, it is important to consider effect of KD on:a. Body composition changeb. Potential negative effect of KD towards vital organsc. Glucose metabolism change

• From a long term perspective on the success of KD, fewer data are available

-Thank you-

QnADoes KD has low intake of protein as well?

No, because KD have different ratio of macronutrients, based on individual needs

Is KD safe for epileptic person?

KD is designed for them, so the main goal is to decrease seizure. It can also give weight loss. But they also have to consult with dietician.

When we consume less carbs, insulin decrease as well. Does the insulin rise again when we stop KD?

Yes, because when someone undergo KD, body will be more sensitive of glucose. But when KD is stopped, the insulin will rise again.