KATRIN HINRICHS EDUCATION Ph.D. · KATRIN HINRICHS CURRICULUM VITAE, page 5 Carrie Hanna, MS...

CURRICULUM VITAE

KATRIN HINRICHS

Professor and Patsy Link Chair in Mare Reproductive Studies Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine

Texas A&M University, College Station, Texas (979) 862-1338; [email protected]

EDUCATION 1985-1988 Ph.D. - May 1988 Biomedical Graduate Group

University of Pennsylvania

1984 Diplomate, American College of Theriogenologists

1982-1984 Resident, Large Animal Reproduction, School of Veterinary Medicine University of Pennsylvania - New Bolton Center

1974-1978 D.V.M. - June 1978, B.S. - June 1976, School of Veterinary Medicine University of California, Davis. Equine Track.

EXPERIENCE 1998-present Texas A&M University College of Veterinary Medicine, College Station, Texas

Patsy Link Chair in Mare Reproductive Studies (2005-present) Professor (2002- present); Associate Professor (1998-2002) Department of Veterinary Physiology and Pharmacology

Joint Appointment, Department of Large Animal Clinical Sciences Conduct research on oocyte meiotic competence, fertilization, nuclear transfer in horse; teach in undergraduate, graduate and professional programs; collaborate with clinical services in Theriogenology. Head, Equine Embryo Laboratory. 1988-1998 Tufts University School of Veterinary Medicine, Grafton, Massachusetts

Associate Professor (1993-1998); Assistant Professor (1988-1993) Department of Clinical Sciences Head, Section of Large Animal Clinical Sciences 1997-1998 Head, Section of Theriogenology 1993-1997

Responsible for clinical caseload in reproduction, all species. Head, equine endometrial biopsy service. Teach didactic and laboratory courses in reproduction, consult with clinicians, practitioners and owners. Conduct research on oocyte maturation and fertilization in the horse. 1982-1988 University of Pennsylvania School of Veterinary Medicine, Kennett Square, Pennsylvania

Lecturer (1984-1988); Resident (1982-1984) Section of Reproductive Studies, New Bolton Center Clinical duty at the Hofmann Center (in-house equine fertility clinic); teaching in professional curriculum: reproduction, all species. Conduct research on hormonal requirements for pregnancy, embryo transfer in the mare. Director, equine endometrial biopsy interpretation service, 1986-1988. 1980-1982 Veterinary Practitioner Glenn, California Dairy reproductive health, obstetrics, surgical emergency, and sick cow work. 1978-1979 Burnham Veterinary Clinic, Willows, California Assistant Veterinarian Two-person mixed animal clinic.

KATRIN HINRICHS CURRICULUM VITAE, page 2

HONORS and AWARDS - Professional 2014 Honorary Research Fellow, University of Liverpool, United Kingdom 2013 Texas Veterinary Medical Association Faculty Achievement Award 2007 Doctor Honoris Causa in Veterinary Medicine, University of Copenhagen, Denmark 2003 Theriogenologist of the Year, American College of Theriogenologists 2001 Richard H. Davis Teaching Award, College of Veterinary Medicine, Texas A&M University 1997 Outstanding Faculty Award, Tufts University 1996 Faculty Commencement Speaker, Class of ’96, Tufts University School of Veterinary Medicine 1992 SmithKline Beecham Award for Research Excellence, Tufts University School of Veterinary Medicine 1990 Hamilton-Thorn Award, Fifth International Symposium on Equine Reproduction, Deauville, France 1978 Phi Zeta Honor Society, Lambda Chapter, School of Veterinary Medicine, University of California, Davis 1977 California Thoroughbred Breeders Scholarship, School of Veterinary Medicine, University of California, Davis 1975 George S. Hart Memorial Scholarship, School of Veterinary Medicine, University of California, Davis HONORS and AWARDS – Other 2014 Outstanding 4-H Adult Leader Award, Brazos 4-H Adult Leaders Association 2010 Horseman of the Year, Texas AgriLife Extension Horse Committee, Brazos County TEACHING College of Veterinary Medicine, Texas A&M University, 1998-

Current teaching Lectures

VTPP 912, Physiology. Lecture 19 hours, Cell cycle, transcription, translation, male and female reproductive physiology; reproductive physiology of individual domestic species. (1999-present)

VTPP 924, Pharmacology/Toxicology. Lecture 1-2 hours: Drugs used in reproductive medicine. (2003-present)

ANSC 434, Animal Reproduction Management Lecture 1 hour: In vitro maturation and fertilization. (2014) ANSC 612, Equine Reproduction. Lecture 2 to 3 hours: Assisted reproductive techniques in the horse. (2008

- present) ANSC 423/621, Issues in the Equine Industry. Lecture 3 hours: Cloning: science, ethics and issues. (2013-

present) VIBS 609, Anatomy and function of reproductive systems. Lecture 2 hours: Contemporary issues in ART.

(2013-present) PHEB 622 Reproductive and Perinatal Epidemiology Lecture 2 hours: Assisted reproductive technologies:

overview and issues (2014) Laboratories

VTPP 659, Gamete and Embryo Physiology. Presentation / laboratory 3 hours; Equine embryo transfer, oocyte collection. (2002-present)

VTPP 948-323,324, Topics in Equine Reproduction. Laboratory 12 hours: mare palpation and ultrasonography. (2001-present)

VTPP 912, Physiology. Laboratory 8-12 hours. Male and female reproductive physiology. (1999-present) Directed Studies—Biomedical Science 485 Problems Course. 1-3 students per year. Completed teaching Lectures

VTPP 335, Physiology for Bioengineers. Lecture 6 hours to each of two sessions: Male and female reproductive physiology. (2000-2012)

VTPP 427, Biomedical Physiology II (fall and spring). Lecture 6 hours: Female reproduction, growth, thyroid. (2004-2005)

VTPP 948-323, 324, Topics in Equine Reproduction. Course Director, 32 hour course. Lecture 12 hours, Discussion of research papers, manipulation of the estrus cycle, clinical issues. (2001-2013)


Laboratories VTPP 948-323,324, Topics in Equine Reproduction. Laboratory 12 hours: mare palpation and

ultrasonography. (2001-2013) Tufts University School of Veterinary Medicine 1988-1998

Lectures Reproductive Physiology Course Director; 25 hr course. Lecture 12-16 hours: Male and female

reproductive physiology; pregnancy and parturition; reproductive physiology of the horse, pig, dog. Theriogenology Course Director; 40 hr course. Lecture 15-20 hours: Equine, porcine and canine

reproduction ; breeding soundness examination; dystocia; problem solving. Clinical Pharmacology Lecture 2 hours: Hormonal therapeutics in reproduction.

Laboratories Equine Theriogenology Course director; 16 hour course. 3rd year laboratory. Teach palpation and

speculum examination; evaluation of post-mortem tracts; demonstration/discussion of breeding soundness examination.

Equine Reproduction I and II (1989-1994) Course director; 32 hour course. 4th year electives. Teach palpation/ultrasonography of reproductive tract, procedures for diagnosis/treatment of equine reproductive disease; discussion of current research.

Senior Large Animal Medicine rotation Clinical teaching in large animal reproduction. Reproduction Elective 10-15 students/year, 1 to 4 weeks each. Clinical teaching in small and large animal

reproduction. Independent Studies -- up to 2 students per year, research in reproduction. Proposal preparation/data collection

(3-4 months) /oral presentation/ manuscript preparation. School of Veterinary Medicine, University of Pennsylvania 1983-1988

Lectures Course 7041; Core Reproduction 6 hours: Patterns and control of the estrous cycle; species differences in

estrous cycle, heat detection and behavior; manipulation of the estrous cycle. Course 7542; Large Animal Reproduction 3 hours: Therapeutics in reproduction; uterine disease and

antimicrobial therapy. Course 7541; Small Animal Reproduction (1986 only) 7 hours: Reproductive physiology and breeding

management of the dog and cat; infertility, dystocia and obstetrical management in small animals. Course 7506; Diseases and management of sheep and goats 3 hours: Reproduction: patterns, diseases and

management of sheep and goats. Course 2001; Core pharmacology 1 hour: Clinical use of prostaglandins.

Laboratories Course 7542; Large Animal Reproduction 24-45 hours: Male and female reproductive pathology; fertility

evaluation of the stallion, boar, bull and ram; obstetrical procedures in the cow and mare; cow palpation; mare palpation and diagnostic techniques.

Course 7741; Senior rotation in large animal reproduction. Breeding soundness examination in the stallion, mare, bull, cow and ram; general clinical teaching.

Independent Studies Course 8999; 0-3 students/year, 4-8 weeks each. Equine reproduction research/clinics.

SPECIAL STUDENTS, GRADUATE STUDENTS, RESIDENTS TRAINED Invited External Appointments

Member of Evaluation Panel, Defense Opponent

Dr. Ingrid Brück Bøgh, DVSc candidate, The Royal Veterinary and Agricultural University, Denmark, 2003-2004

Member of Graduate Supervisory Committee

Dr. Niamh Lewis, PhD Candidate, Faculty of Health & Life Sciences, University of Liverpool, 2014-present

Sheila Spacek, MS Candidiate, Department of Biological Sciences, Colorado State University, 2014-present


College of Veterinary Medicine, Texas A&M University

Post-Doctoral Trainees

Dr. Orlando Valenzuela, research in oocyte developmental capacity, 2015-present

Dr. Heloisa Canesin, research in vitrification of equine oocytes, 2014-present

Dr. Shavahn Loux, research in factors affecting motility in demembranated equine sperm, 2014

Dr. Beatriz Macías García, research in sperm capacitation and in vitro fertilization, 2011- 2012

Dr. Lauro González Fernández, research in sperm capacitation and hyperactivation, 2011-2012

Dr. Isabel Catalina Velez Jaramillo, research in oocyte maturation, sperm capacitation and fertilization, 2009-2012; Diplomate, American College of Theriogenologists, August 2012.

Dr. Candace Jacobson, research in synchronization for transvaginal follicle aspiration, 2008-2009

Dr. Young Ho Choi, research in oocyte maturation, IVF, and nuclear transfer, 2000- 2003

Dr. Charles C. Love, research in oocyte maturation and IVF, 1999- 2003

Graduate Students – Major Advisor (Chair of Graduate Advisory Committee)

Paola Tinetti Pinto, PhD candidate, Department of Veterinary Physiology and Pharmacology 2013-

Sicilia Grady, PhD candidate, Department of Veterinary Physiology and Pharmacology 2013-

Leticia Vivani, PhD candidate, (Co-chair, Major Advisor), Biomedical Sciences, 2012-

Shavahn Loux, PhD candidate, Department of Veterinary Physiology and Pharmacology 2009-2013 (PhD 2013)

Kristin Rolke, MS candidate, Department of Veterinary Physiology and Pharmacology 2006-2008 (MS 2008)

Lance Roasa, MS candidate, Department of Veterinary Physiology and Pharmacology, 2003-2007 (MS 2007)

Heather Darby, MS candidate, Department of Veterinary Physiology and Pharmacology, 2003-2005 (MS 2005)

Graduate Students -- Member of Graduate Advisory Committee

Raul Valdez, PhD candidate, Department of Animal Sciences, 2012-

Shelby Hayden, MS candidate, Biomedical Sciences, 2008-2013

Sarah Stiehl, MS candidate (non-thesis), Biomedical Sciences, 2012–2013

Ciera Guardia, MS candidate, Department of Animal Science, 2009-2011

Michaelle K. Blake, MS candidate, Department of Animal Science, 2007-2010

Randi L. Manier, MS candidate, Department of Veterinary Physiology and Pharmacology 2007-2009

Lauren Foster, MS candidate, Biomedical Science, 2007- 2009

Isabel Catalina Velez Jaramillo, MS candidate, Department of Animal Science, 2007-2009

Richard H. L. Chichester, MS candidate (non-thesis), Biomedical Science, 2007-2008

Lynn F. Commaille, MS candidate, Department of Animal Science, 2007-2008

Sommer Morgan, MS candidate, Department of Animal Science, 2006-2007

Jessica Epple-Farmer, PhD candidate, Department of Pathobiology, 2003-2008

Christopher J. Mortensen, PhD candidate, Department of Animal Science, 2004-2007

Dee A. Cooper, MS candidate, Department of Animal Science, 2004-2005

Stephanie Morton, MS candidate, Department of Animal Science, 2002-2004

Laura Willingham, MS candidate; PhD candidate, Department of Veterinary Physiology and Pharmacology, 1999-2008

Ryan Gandy, PhD candidate, Wildlife and Fisheries Sciences, 2002 – 2004 (Graduate Council Representative)

Michael D. Julian, PhD candidate, Chemistry, 2000-2003 (Graduate Council Representative).

Jennifer Young, MS candidate, Department of Animal Science, 1999-2005

Choo Young Yoo, PhD candidate, Educational Human Resource Development, 1999-2002 (Graduate Council Representative).


Carrie Hanna, MS candidate, Department of Veterinary Physiology and Pharmacology, 1999-2001

Special Status Students

Jody D Norris, 1st year veterinary student, 2012. Summer Veterinary Student Research Fellowship Program. Project: Isolation, culture and characterization of somatic cells from frozen equine semen.

Elizabeth Roberts, 1st year veterinary student, 2011. Summer Veterinary Student Research Fellowship Program. Project: Effect of capacitation conditions on sperm intracellular pH, calcium and protein tyrosine phosphorylation.

Christine Elkins, undergraduate student, 2010. NIH/NSF Summer Undergraduate Research Experience program. Project: Changes in intracellular pH and calcium levels associated with hyperactivated motility of equine spermatozoa.

Angela Gracia, undergraduate student, 2010. NIH/NSF Summer Undergraduate Research Experience program. Project: Identification and localization of IP3 receptors and calreticulin in equine spermatozoa.

Noah Grimes, undergraduate student, 2010. NIH/NSF Summer Undergraduate Research Experience program. Project: Project: Changes in intracellular pH and calcium levels associated with hyperactivated motility of equine spermatozoa.

Rachael Horil, undergraduate student, 2010. NIH/NSF Summer Undergraduate Research Experience program. Project: Identification and localization of IP3 receptors and calreticulin in equine spermatozoa.

Erin Reynolds, 1st year veterinary student, 2009. Summer Veterinary Student Research Fellowship Program. Project: Verification of CatSper1 protein in equine sperm.

Brandon Torrance, 1st year veterinary student, 2009. Summer Veterinary Student Research Fellowship Program. Project: Effect of media and incubation conditions on procaine-induced hyperactivated motility in equine sperm.

Erica Thornton, 1st year veterinary student, 2008. Summer Veterinary Student Research Fellowship Program. Project: Effect of calcium ionophore on hyperactivated motility in stallion spermatozoa

Kelly Sulik, 1st year veterinary student, 2007. Summer Veterinary Student Research Fellowship Program. Project: Induction of hyperactivated motility in stallion spermatozoa.

Patsy S. Morris, 1st year veterinary student, 2006. Summer Veterinary Student Research Fellowship Program. Project: Comparison of DNA methylation between equine embryos produced by nuclear transfer and intracytoplasmic sperm injection.

Amy C. Boyer, 1st year veterinary student, 2006. Summer Veterinary Student Research Fellowship Program. Project: The effects of procaine on equine spermatazoal motility and fertilization rate in vitro.

Abby D. Obermiller, 1st year veterinary student, 2005. Summer Veterinary Student Research Fellowship Program. Project: Oct-4 Expression in the Equine Embryo.

Barbie J. Gadsden, 2nd year veterinary student (Tuskegee University), 2005. Summer Veterinary Student Research Fellowship Program. Project: Methylation status of the male pronucleus in horse zygotes.

Cindy Johnson, Public Health/Allied Health Summer Research Student, 2000. Project: Meiotic competence of horse oocytes co-cultured with theca cells.

Christina A. Reinoehl, 1st year veterinary student, 1999. Veterinary Student Summer Research Program. Project: Effect of 6-dimethylaminopurine and okadaic acid on meiotic competence of equine oocytes. Tufts University School of Veterinary Medicine Note: Tufts School of Veterinary Medicine did not have a graduate degree program at this time.

Clinical Trainees

Carlos M. Gradil, Fellow, Equine Reproduction, March-August 1998

Anne E. Domit, Intern, Canine Reproduction, 1997-1998.

Sylvia J. Bedford, Resident, Theriogenology, 1993-94. Clinical and research training in large and small animal reproduction.

Ann L. Schmidt, Resident, Theriogenology, 1991- 1993. Clinical and research training in large and small animal reproduction.



Mary Masterson, 2nd - 4th year veterinary student, 1997-1999. NIH Short-term Training Grant. Awarded DVM with Thesis, May 1999.

April Hanrahan Schick, 2nd year veterinary student, 1997. NIH Short-term Training Grant.

Kimberly A. Williams, 2nd year veterinary student, 1993. NIH Short-term Training Grant. Awarded DVM with Thesis, May 1996.

Liesl R. Hawley, 3rd year veterinary student, 1993. NIH Short-term Training Grant. Awarded DVM with Thesis May 1995. Outstanding Senior Thesis, 1995.

Marianne G. Martin, 3rd year veterinary student, 1991. NIH Short-term Training Grant. Second Prize, Tufts NIH summer research competition 1991. Awarded DVM with Thesis May 1993.

Pam P. Friedman, 2nd and 3rd year veterinary student, 1990, 1991. NIH Short-term Training Grant. First Prize, Tufts NIH summer research competition 1990. Awarded DVM with Thesis May 1993.

Elisa Harvey, 3rd year veterinary student, 1990. Tufts Summer Research Award. School of Veterinary Medicine, University of Pennsylvania-New Bolton Center

Participated in the clinical and research training of the following interns and residents in the Section of Reproductive Studies, 1983-1988:

Fernando L. Riera, Intern 1987-88, Resident, 1988-90

Phillip R. Hunt, Resident, 1986-1988.

Charles C. Love, Resident, 1984-1987

Patricia L. Sertich, Resident, 1983-1985.


Donald F. Kenney, 3rd year veterinary student, Summer 1985. Independent study in equine reproduction. VISITING SCHOLARS

Hélène Resende, DVM, MS, São Paulo State University, Botucatu, Brazil, July-October 2014. Research on reactive oxygen species in equine sperm.

Karoline Paulussi, Senior veterinary student, Faculdade de Medicina Veterinária de Araçatuba, Universidade Estadual Paulista, Brazil, July-October 2014. Externship in equine assisted reproduction; research on effect of progesterone treatment on prevention of hemorrhagic anovulatory follicles after follicle ablation.

Mehmet Can Gündüz, DVM, Faculty of Veterinary Medicine, University of Istanbul, Turkey, April-May 2014. Experience in follicle aspiration and laboratory techniques for oocyte collection.

Juao Luna, DVM, Universidade Estadual do Norte Fluminense, Campos dos Goytacazes – RJ, Brazil, February – December 2014. Research on immune-isolation of viable somatic cells from frozen-thawed equine semen.

Heloisa Canesin, DVM, São Paulo State University, Botucatu, Brazil, May–November 2013. Experience in biotechnology of equine reproduction for Master’s degree; research on vitrification of equine oocytes.

Isabel Ortiz Jaraba, DVM, University of Cordoba, Spain, May–July 2013. Externship in assisted equine reproduction for PhD degree; research on vitrification of equine oocytes.

Mouhamadou Diaw, DVM, Lecturer, North Carolina State University College of Veterinary Medicine, April, 2013. Experience in oocyte manipulation and maturation.

Monique de Albuquerque Lagares, DVM, Professor, University of Minas Gerais, Brazil, January-December 2013. Sabbatical: Research on embryo-maternal interactions in the horse.

Morgan Agnew, 4th year veterinary student, University of Pennsylvania, May 2012. Externship in assisted equine reproduction.

Niamh Lewis, BVMS MRCVS, Resident, University of Liverpool School of Veterinary Science, March, 2012. Experience in equine oocyte recovery and culture.


Beatriz Macías García, DVM, Department of Reproduction and Obstetrics, College of Veterinary Medicine, University of Extremadura, Spain. March – October 2011. Experience in oocyte recovery, maturation and fertilization.

Maria Elena Dell’Aquila, PhD, Professor, Faculty of Biotechnological Sciences, University of Bari, Italy. February 2010. Experience in equine intracytoplasmic sperm injection and embryo culture; chromatin changes after sperm injection.

Jaime Roldán, DVM and Fernando Riera, DVM Centro de Reproducción Equina Doña Pilar, Lincoln, Argentina, July 2009. Clinical and research experience in in vitro oocyte and embryo manipulation.

Devender Kumar, DVM. Breeding Officer 1, Equine Breeding Stud, Babugarh, Gaziabad, India. April – June 2007. Research on recovery and intracytoplasmic sperm injection of in vivo-matured equine oocytes.

Hannelore Alm, PhD, Department of Reproductive Biology, Research Institute for the Biology of Farm Animals, Dummerstorf, Germany. April – May 2007. Study on effect of pulse frequency during sperm injection on fertilization rates of bovine oocytes.

Roberto Sanchez, DVM, Resident veterinarian, Schockemohle Breeding Farm, Muhlen, Germany. September – October 2006. Research on gonadotropin induction of oocyte maturation in vivo.

Morten Petersen, PhD student, Royal Veterinary and Agricultural University, Denmark, October – December 2005. Research in inhibition of oocyte maturation with roscovitine.

Salvador Romo, DVM, Professor, Universidad Nacional Autonoma de Mexico, May – August 2004. Research in equine in vitro fertilization.

Bertrand Walckenaer, Institute National Agronomique Paris-Grignon, France, March – August 2003. Research on effect of delay to oocyte recovery on developmental competence of horse oocytes. Awarded Medaille d’Argent de L’Academie, 2005, from the Academie d’Agriculture de France for this research.

Lilian Clarion Franz, PhD candidate, Colorado State University, October-November, 2001. Conduct research project on effect of roscovitine inhibition on cytoplasmic maturation of horse oocytes.

Eric Palmer, Former Director, Equine Unit, Institut National de Recherche Agronomique, Nouzilly, France. December, 2000. Research experience in equine nuclear transfer.

Fernando Riera, DVM, Director, Centro de Reproducción Equina Doña Pilar, Lincoln, Argentina, April-May 1998; August-September 1999; June 2001. Clinical and research experience in oocyte maturation and oocyte transfer in the mare.

Hanne Pedersen, DVM, PhD candidate Department of Clinical Studies, Royal (Dick) College of Veterinary Medicine, Edinburgh, Scotland. March-April 1997. Study on association of follicular factors with oocyte chromatin and cumulus status in the horse.

Hannelore Alm, PhD, Department of Reproductive Biology, Research Institute for the Biology of Farm Animals, Dummerstorf, Germany. September-October 1995. Study on effect of cycloheximide on horse oocyte maturation.

Isabelle LeNormand, Institut National de Recherche Agronomique, Nouzilly, France. August-September 1987. Experience in equine embryo transfer. PROFESSIONAL MEMBERSHIPS and AFFILIATIONS

American Veterinary Medical Association International Embryo Transfer Society American Association of Equine Practitioners Society for the Study of Reproduction American College of Theriogenologists Society for Theriogenology Assistant Editor, The Cornell Veterinarian 1990-1993 Editorial Board Memberships Theriogenology, 2014- Animal Reproduction, 2005- Theriogenology, 1994-1999


Grant reviewer: U.S.D.A. National Research Initiative Competitive Grants Horserace Betting Levy Board (Britain) Research Grants Member, Grant Review Committee for the Italian Ministry for Education, University and Research (MIUR), 2002- Peer Reviewer, Italian Evaluation of Research Quality (VQR), 2012- Team Leader, Certifying Examination question development subcommittee (biotechnology/assisted reproductive

techniques), American College of Theriogenologists, 2005-2006 Reviewer for Certifying Examination, American College of Theriogenologists 1993-1997 Faculty Representative for Tufts University, Society for Theriogenology, 1991-1998

Ad Hoc Reviewer: Acta Veterinaria Scandinavica American Journal of Veterinary Research Animal Reproduction Science Biology of Reproduction Cloning and Stem Cells Domestic Animal Reproduction Equine Veterinary Journal Equine Nutrition and Physiology Symposium IPPOLOGIA (Journal of the Italian Equine Veterinary Society) Journal of the American Veterinary Medical Association Journal of Animal Science

Journal of Equine Veterinary Science Journal of Reproduction and Development Molecular Human Reproduction Molecular Reproduction and Development Proceedings, International Embryo Transfer Society Reproduction Reproduction in Domestic Animals Stem Cells and Development Theriogenology Veterinary Medicine

COMMITTEES National, International

Domestic Animal Biomedical Embryology committee, International Embryo Transfer Society, 2007- Secretary, 2008-2014 Biotechnology Committee, American College of Theriogenologists, 2000-2008

International Equine Reproduction Symposia Committee, 1992-2008 Education Committee, Society for the Study of Reproduction, 1997-2002

Scientific Information Committee, American College of Theriogenologists, Chair, 1996-1997 Texas A&M University

University Executive Committee, Interdepartmental Faculty of Reproductive Biology, 2010- Nominating Committee, 2010-2013, Chair, Nominating Committee 2011-2013 Search Committee, faculty position in the Department of Animal Science, 2009 Drafting Committee, white paper on Integrative Center for Reproduction and Health 2008-2009 Search Committee, faculty position in the Department of Animal Science, 2004-2005 Faculty Recruitment Team, Signature Program in Reproductive Biology 2003-2005 Committee on Graduate Programs, Faculty of Reproductive Biology, 1999-2004 Nominating Committee, Interdisciplinary Faculty of Reproductive Biology, 1999-2001 Organizing Committee, Annual Reproductive Physiology Symposium, 2000

College of Veterinary Medicine Clinical Research Review Committee, School of Veterinary Medicine, 1999- Research Peer Review Committee, Promotion and Tenure, Department of Veterinary Pathobiology, 2010. Search Committee, faculty position in Veterinary Physiology and Pharmacology, 2008-2009 Teaching Review Committees, VTPB and VIBS, 2007 Academic Appeals Committee, 2004-2005 Search Committee, faculty position in Veterinary Anatomy and Public Health, 2003-2004 Search Committee, Chair in Equine Reproduction, School of Veterinary Medicine, 2000-2001 Scholarships and Awards Committee, School of Veterinary Medicine, 1999-2002


Tufts University School of Veterinary Medicine

Faculty Appointments and Promotions Committee, 1993-1998 Chair, 1997-1998 Executive Faculty Board, 1997-1998 Institutional Animal Care and Use Committee, 1995-1998; Vice-Chair, 1997- 1998

Clinical Council, 1997-1998 Advanced Education Committee, 1993- 1998. Chair, 1994-1997

Head, Graduate Program Development Subcommittee, 1993-1998 Faculty Council, 1996-1998 Search Committee, Head of Department of Laboratory Animal Medicine, 1997 Editorial Advisory Board, Horse! 1995-1997 Intradepartmental Promotions Committee, 1993-1995. Chair, 1993-1994 Executive Faculty Board, 1991- 1992 Subcommittee for Alternatives in Large Animal Laboratories, 1990 Faculty Council, 1990-93. Moderator, 1992 Faculty Forum NIH Summer Research Awards Review Committee, 1990, 1996 Intradepartmental Promotions Committee, 1990-1992 Student Promotions Committee, 1990-91 Advanced Education Committee, 1989-92 School of Veterinary Medicine, University of Pennsylvania

Emergency fee fund committee 1985-1988 Clinical teaching evaluation committee 1987-88 Medical records committee 1986-88 Search committee, Assistant Professorship in Reproductive Studies, 1986-87 Search committee, Lectureship in Reproductive Studies, 1986

CONFERENCES, SYMPOSIA ORGANIZED/CHAIRED

Session Chair, Robert M. Kenney Symposium on Reproduction, Kennett Square, Pennsylvania, September 26, 2014.

Workshop moderator, Methods for collection of equine oocytes, 11th International Symposium on Equine Reproduction, Hamilton, New Zealand, January 30, 2014.

Section Editor, Sperm Injection, Annual Conference of the International Embryo Transfer Society, Reno, Nevada, January, 2014.

Session Chair, ICSI and Oocytes, 8th International Symposium on Equine Embryo Transfer, Vancouver, Canada, July 27, 2012.

Section Editor, Oocyte maturation, Annual Conference of the International Embryo Transfer Society, Phoenix, Arizona, January 2012.

Co-Convener, Havemeyer Foundation Symposium on Equine Gametes, Hilton Head, North Carolina, October 2011.

Session Leader/Coordinator, In-Depth Session on Equine Assisted Reproduction, American Association of Equine Practitioners Annual Convention, Baltimore, Maryland, December 2010.

Chair, Workshop “ICSI-Embryos in Horses: State of the ART” Annual Conference of the European Society for Domestic Animal Reproduction, Ghent, Belgium, September, 2009.

Co-Chair, Artificial Insemination in Wild Ungulates, IETS Post-Conference Satellite Symposium, Implementation of Artificial Insemination in Companion Animals,Non-Domestic and Endangered Species, San Diego, California, January, 2009.


As member of the International Equine Reproduction Symposia Committee, helped to organize the 6th, 7th, 8th and 9th International Symposia on Equine Reproduction (ISER).

Senior Convener, Conception and Early Embryo Development, 9th ISER, Rolduc, Netherlands (2004-2006)

Senior Convener, Conception and Early Embryo Development, 8th ISER, Fort Collins, Colorado (2000-02)

Senior Convener, Gametes and Early Embryo Development, 7th ISER, Pretoria, South Africa (1997-98)

Co-Convener, Pregnant Mare, 6th ISER, Caxambu, Brazil (1993-94)

Section Editor, Sperm Injection, Annual Conference of the International Embryo Transfer Society, Orlando, Florida, January, 2006.

Co-Convener (North America), 4th Meeting of the International Equine Gamete Group, Kühlungsborn, Germany, September 18-21, 2005. Chair, Session II: Oocytes.

Co-Convener, Equine Oocyte Forum, Copenhagen, Denmark, January 7, 2005.

Co-Convener /Co-Chair, Symposium on Equine Reproduction, 15th International Congress on Animal Reproduction, Porto Seguro, Brazil, August 8-12, 2004.

Co-Chair, Session IV (Functional Genomic Analysis of Oocyte Maturation), Annual Conference of the International Embryo Transfer Society, Portland, Oregon, January 12, 2004.

Chair, Session on Oocyte Developmental Competence, Havemeyer Foundation Workshop: Transporting Equine Gametes and Embryos, Brewster, Massachusetts, October 3, 2003.

Chair, Session on In Vitro Fertilization and ICSI, 8th International Symposium on Equine Reproduction, Fort Collins, Colorado, July 25, 2002.

Chair, Session on Sperm Cryopreservation, Havemeyer Foundation Workshop: From Epididymis to Embryo, New Orleans, Louisiana, October 19, 2001.

Chair, Session on Commercial Embryo Transfer, 5th International Symposium on Equine Embryo Transfer, Saari, Finland, July 7, 2000.

Co-chair, Practical aspects of embryo technology. Annual Conference, International Embryo Transfer Society. Maastricht, The Netherlands, January 9, 2000

Chair, Session on Fertilization, 7th International Symposium on Equine Reproduction, Pretoria, South Africa, July 16, 1998.

Chair, Session on Oocyte Fertilization; 4th International Symposium on Equine Embryo Transfer and Other Advanced Techniques. Reims, France, January 17, 1997.

Chair, Session on sperm-oviduct interactions. 6th International Symposium on Equine Reproduction, Caxambu, Brazil, August 9, 1994.

RESEARCH SUPPORT Current support

2014-15 Program Coordinator: $100,000 (Link Equine Research Endowment Fund). Equine Gamete Studies.

2012-22 Principal Investigator: $126,000 (Private individual) Nuclear transfer with a specific cell line

2008-14 Co-investigator: $1,428,500 (Legends Premier Stallion Season Auction). Equine reproductive studies. PI: Dr. Dickson Varner.

External Grant Consultant

2014-16 Beca para lo obtención de la mención internacional de la tesis (Campus Agroalimentario Internacional - ceiA3); PI: Dr. Manuel Hidalgo, University of Cordoba, Spain.

Completed Support

2011-14 Principal Investigator: $126,000 (Private individual) Developing nuclear transfer (NT) and in vitro embryo culture methods for production of NT blastocysts from a specific oocyte mitochondrial genotype.


2012-13 Mentor: $10,000 (Texas A&M College of Veterinary Medicine Postdoctoral Trainee Research Grant). The role of protein kinase A and calcium-calmodulin signaling in the regulation of hyperactivated motility of equine sperm. (PI, Dr. Beatriz Macías García).

2009-14 Program Coordinator: $480,000 (Link Equine Research Endowment Fund). Equine Gamete Studies.

2009-11 Principal Investigator: $100,000 (Private individual) Unrestricted donation.

2008-11 Principal Investigator: $194,804 (American Quarter Horse Association) Biopsy of equine embryos for preimplantation genetic diagnosis, and subsequent cryopreservation

2008-10 Principal Investigator: $100,800 (Private individual) Equine nuclear transfer with specific cell lines.

2006-09 Principal Investigator: $189,000 (Private individual) Equine nuclear transfer with specific cell lines.

2005-09 Co-Program Coordinator: $390,000 (Link Equine Research Endowment Fund). Equine Reproductive Studies Program. Group leader for Oocyte Maturation and Fertilization Mechanisms, ~50% of allocated funds.

2005-07 Principal investigator: $47,200 (Texas Equine Research Fund) “Establishment of embryonic stem cells in the horse”

2005-07 Principal investigator: $165,000 (Private individual) Equine nuclear transfer with a specific cell line.

2005-06 Principal investigator: $37,314 (American Quarter Horse Association) “Transport of ovaries for assisted reproduction.”

2004-06 Principal investigator: $50,000 (Smart Little Lena Syndicate). Equine nuclear transfer with a specific cell line.

2004-05 Principal investigator: $44,412 (American Quarter Horse Association). “Methods for efficient utilization of stallion semen” (continuation).

2003-05 Principal investigator: $150,000 (Private Industry) Equine nuclear transfer with a specific cell line.

2003-05 Co-principal investigtor: $125,000 (Private donations: Black Rock Ranch and others; PI DD Varner). Intracytoplasmic sperm injection and other methods for fertilization.

1999-05 Co-principal investigator: $951,728 (Link Equine Research Endowment Fund) “Mechanisms controlling testicular function; mechanisms of oocyte maturation and fertilization” Group leader for Oocyte Maturation and Fertilization Mechanisms, ~50% of allocated funds.

2003-04 Principal investigator: $32,688 (American Quarter Horse Association). “Methods for efficient utilization of frozen stallion semen.”

2003-04 Co-principal investigator: $25,000 (CONACYT [El Consejo Nacional de Ciencia y Tecnologia] Collaborative Research Grant Program) “In Vitro Fertilization in the Horse.”

2000-01 Co-principal investigator: $1,321,451 (Bio-Arts and Research Corporation, Inc., PI: Mark Westhusin.) “Cloning adult dogs by nuclear transplantation: a continuation of the Missyplicity project” PI for Horse section.

1999-01 Principal investigator: $138,000 (College of Veterinary Medicine Signature Program Funding) “Equine gamete physiology: IVF and cloning”

1996-97 Principal investigator: $10,000 (Massachusetts Horse Racing Research Fund) “Oocyte transfer: Effect of maturation time on embryo development”

1994-95 Co-principal investigator (faculty advisor): $3,600 (Massachusetts Horse Racing Research Fund; PI: S.J. Bedford) “Capacitation of horse spermatozoa for penetration of zona-free horse oocytes”

1992-93 Co-principal investigator (faculty advisor): $5,600 (Massachusetts Horse Racing Research Fund; PI: A.L. Schmidt) “Induction of activation of in vitro matured horse oocytes.”


1990-93 Principal investigator: $208,000 (USDA Competitive Grants Program) “Development of horse oocytes transferred to the follicle of the mare.”

1990-95 Principal investigator: $50,000 (Private Donation: Mr. Austin Mason) “Development of a clinical oocyte transfer technique”

1989-90 Principal investigator: $10,890 (Massachusetts Thoroughbred Breeders Research Fund) “In vivo maturation of equine oocytes.”

1989-90 Principal investigator: $30,000 (Beecham Laboratories) “Use of ticarcillin-clavulanate for treatment of endometritis due to Pseudomonas aeruginosa in mares.”

1988-89 Principal investigator: $13,000 (Massachusetts Thoroughbred Breeders Research Fund) “Control of oviductal transport of embryos in the horse.”

1985-87 Principal investigator: $58,000 (Grayson Foundation) “Effect of timing of estrogen and progesterone administration on pregnancy rate after embryo transfer in ovariectomized mares.”

1986-87 Principal investigator: $2,400 materials (Steris Laboratories) “Effect of timing of progesterone ad-ministration on pregnancy rate after embryo transfer in ovariectomized mares.”

1986 Principal investigator: $2,000 materials (Cambridge Life Sciences) “Use of an immediate qualitative progesterone assay for determination of day of ovulation in an equine embryo transfer program.”

1985 Principal investigator: $3,000, plus $2,000 materials (Hoechst-Roussel Agri-Vet Company) “Use of altrenogest to prepare ovariectomized mares as embryo transfer recipients.”

1984 Co-investigator: $50,000 (Private donation: Ms. Laura Thorn. PI: Dr. R.M. Kenney) “Pregnancy in ovariectomized mares achieved by embryo transfer.”

PROFESSIONAL PUBLICATIONS Publications in refereed journals: Reports of original research Choi YH, Velez IC, Macías-García B and Hinrichs K. Timing factors affecting blastocyst development in equine somatic cell nuclear transfer. Cell. Reprogram. (in press). Choi YH, Penedo MCT, Daftari P, Velez IC and Hinrichs K. Accuracy of preimplantation genetic diagnosis in equine in vivo-recovered and in vitro-produced blastocysts. Reprod. Fertil. Dev. (in press). Ing NH, Brinsko SP, Curley Jr KO, Forrest DW, Love CC, Hinrichs K, Vogelsang MM, Varner DD and Welsh Jr TH. Dexamethasone acutely regulates endocrine parameters in stallions and subsequently affects gene expression in testicular germ cells. Anim. Reprod. Sci. 152:47-54 (2015). Loux SC, Macías-García B, González-Fernández L, DeSiqueira Canesin H, Varner DD and Hinrichs K. Regulation of axonemal motility in demembranated equine sperm. Biol. Reprod. 91:152, 1-16 (2014). Macías-García B, González-Fernández L, Rocha AM, Guimarães T, Peña FJ, Varner DD and Hinrichs K. Effect of calcium, bicarbonate and albumin on capacitation-related events in equine sperm. Reproduction 149:87-99 (2014). Hayden SS, Blanchard TL, Brinsko SP, Varner DD, Hinrichs K and Love CC. The “dilution effect” in stallion sperm. Theriogenology 83:772-777 (2014). Martino NA, Dell’Aquila ME, Filioli Uranio MF, Rutigliano L, Nicassio M, Lacalandra GM and Hinrichs K. Effect of holding equine oocytes in meiosis inhibitor-free medium before in vitro maturation and of holding temperature on meiotic suppression and mitochondrial energy/redox potential. Reprod. Biol. Endocrin. 12:99, 1-12 (2014).


Whigham AR, Blanchard TL, Love CC, Teague SR, Brinsko SP, Welsh Jr TH, Hinrichs K, Varner DD. Equine semen quality following sperm exposure to seminal plasma stored under different conditions. Clinical Theriogenology 6: 459-466 (2014). Choi YH, Ritthaler J and Hinrichs K. Production of a mitochondrial-DNA identical cloned foal using oocytes recovered from immature follicles of selected mares. Theriogenology 82:411-417 (2014). Loux SC, Crawford KR, Ing NH, González-Fernández L, Macías-García B, Love CC, Varner DD, Velez IC, Choi YH and Hinrichs K. CatSper and the relationship of hyperactivated motility to intracellular calcium and pH kinetics in equine sperm. Biol. Reprod. 89:123, 1-15 (2013). Foss R, Ortis H and Hinrichs K. Effect of potential oocyte transport protocols on blastocyst rates after ICSI in the horse. Equine Vet. J. 45, Suppl. 45:39-43 (2013). González-Fernández L, Macías-García B, Loux SC, Varner DD, Hinrichs K. Focal adhesion kinases and calcium/calmodulin-dependent protein kinases regulate protein tyrosine phosphorylation in stallion sperm. Biol. Reprod. 88:138, 1-12 (2013). Vernunft A, Alm H, Tuchscherer A, Kanitz W, Hinrichs K and Torner H. Chromatin and cytoplasmic characteristics of equine oocytes recovered by transvaginal ultrasound-guided follicle aspiration are influenced by the developmental stage of their follicle of origin. Theriogenology 80:1-9 (2013). Choi YH, Norris JD, Velez IC, Jacobson CC, Hartman DL and Hinrichs K A viable foal obtained by equine somatic cell nuclear transfer using oocytes recovered from immature follicles of live mares. Theriogenology 79: 791-796 (2013). Hinrichs K, Choi YH, Norris JD, Love LB, Bedford-Guaus SJ, Hartman DL and Velez IC. Evaluation of foal production following intracytoplasmic sperm injection and blastocyst culture of oocytes from ovaries collected immediately before euthanasia or after death of mares under field conditions. J. Am. Vet. Med. Assoc. 241:1070-1074 (2012). Velez IC, Arnold C, Jacobson CC, Norris JD, Choi YH, Edwards JF, Hayden SS and Hinrichs K. Effects of repeated transvaginal aspiration of immature follicles on mare health and ovarian status. Equine Vet. J. 44, Suppl 43:78-83 (2012). González-Fernández L, Macías-García B, Velez IC, Varner DD, Hinrichs K. Calcium-calmodulin and pH regulate protein tyrosine phosphorylation in stallion spermatozoa. Reproduction 144:411-422 (2012). Cavinder CA, Burns SA, Coverdale JA, Hammer CJ Holub G and Hinrichs K. Late gestational nutrition of the mare and potential effects on endocrine profiles and adrenal function of the offspring. Prof. Anim. Scientist 28:344-350 (2012). Hayden SS, Blanchard TL, Brinsko SP, Varner DD, Hinrichs K and Love CC. Pregnancy rates in mares inseminated with 0.5 or 1 x 106 sperm using hysteroscopic or transrectally guided deep-horn insemination techniques. Theriogenology 78:914-920 (2012). Choi YH, Varner DD, Love CC, Hartman DL and Hinrichs K. Production of live foals via intracytoplasmic injection of lyophilized sperm and sperm extract in the horse. Reproduction, 142:529-538 (2011). Foster ML, Love CC, Varner DD, Brinsko SP, Hinrichs K, Teague S, LaCaze K, and Blanchard TL. Comparison of methods for assessing integrity of equine sperm membranes. Theriogenology 76:334-341 (2011). Choi YH, Velez IC, Riera FL, Roldán JE, Hartman DL, Bliss SB, Blanchard TL, Hayden SS and Hinrichs K. Successful cryopreservation of expanded equine blastocysts. Theriogenology 76:143-152 (2011).


Foster ML, Varner DD, Hinrichs K, Teague S, LaCaze K, Brinsko SP, Blanchard TL and Love CC. Agreement between measures of total motility and membrane integrity in stallion sperm. Theriogenology 75:1499-1505 (2011). Choi YH, Gustafson-Seabury A, Velez IC, Hartman DL, Bliss S, Riera FL Roldán JE, Chowdhary B and Hinrichs K. Viability of equine embryos after puncture of the capsule and biopsy for preimplantation genetic diagnosis. Reproduction, 140:893-902 (2010). Mortensen CJ, Choi YH, Ing NH, Kraemer DC, Vogelsang MM and Hinrichs K. Heat shock protein 70 gene expression in equine blastocysts after exposure of oocytes to high temperatures in vitro or in vivo after exercise of donor mares. Theriogenology 74:374-383 (2010). Johnson AK, Clark-Price SC, Choi YH, Hartman DL, and Hinrichs K. Physical and clinicopathologic findings in foals produced by somatic cell nuclear transfer – 14 cases (2005-2008). J. Am. Vet. Med. Assoc. 236:983-990 (2010). Jacobson CC, Choi YH, Hayden SS and Hinrichs K. Recovery of mare oocytes on a fixed biweekly schedule, and resulting blastocyst formation after intracytoplasmic sperm injection. Theriogenology 73:1116-1126 (2010). Choi YH, Harding HD, Obermiller AD, Hartman DL, Kurosaka S, McLaughlin KJ, and Hinrichs K. The uterine environment modulates trophectodermal POU5F1 levels in equine blastocysts. Reproduction 38: 589-599 (2009). Choi YH, Hartman DL, Fissore RA, Bedford-Guaus SJ and Hinrichs K. Effect of sperm extract injection volume, injection of PLCζ cRNA, and tissue cell line on efficiency of equine nuclear transfer. Cloning Stem Cells 11: 301-308 (2009). McPartlin LA, Suarez SS, Czaya CA, Hinrichs K and Bedford-Guaus SJ. Hyperactivation of stallion sperm is required for successful in vitro fertilization of equine oocytes. Biol. Reprod. 81:199-206 (2009). Mortensen CJ, Choi YH, Hinrichs K, Ing NH, Kraemer DC, Vogelsang SG and Vogelsang MM. Embryo recovery from exercised mares. Anim. Reprod. Sci.110:237-244 (2009). Bedford-Guaus SJ, Yoon S-Y, Fissore RA, Choi Y-H and Hinrichs K. Microinjection of mouse PLC complementary RNA into mare oocytes induces long-lasting intracellular calcium ([Ca2]i) oscillations and embryonic development. Reprod. Fertil. Dev. 20:875-883 (2008). Alm H, Choi YH, Love L, Heleil B, Torner H and Hinrichs K. Holding bovine oocytes in the absence of maturation inhibitors: kinetics of in vitro maturation and effect on blastocyst development after in vitro fertilization. Theriogenology 70:1024-1029 (2008). Ribeiro BI, Love LB, Choi YH and Hinrichs K. Transport of equine ovaries for assisted reproduction. Anim. Reprod. Sci.108:171-179 (2008). Hanna C, Long C, Hinrichs K, Westhusin M and Kraemer D. Assessment of canine oocyte viability after transportation and storage under different conditions. Anim. Reprod. Sci. 105:451-456 (2008). Hinrichs K, Choi YH, Varner DD and Hartman DL. Production of cloned horse foals using roscovitine-treated donor cells and activation with sperm extract and/or ionomycin. Reproduction 134:319-325 (2007). Hinrichs K, Choi YH, Walckenaer BE, Varner DD, and Hartman DL. In vitro-produced equine embryos: production of foals after transfer to recipient mares, assessment by differential staining, and effect of medium calcium concentrations during culture. Theriogenology 68:521–529 (2007). Roasa LM, Choi YH, Love CC, Romo S, Varner DD and Hinrichs K. Ejaculate and type of freezing extender affect rates of fertilization of horse oocytes in vitro. Theriogenology 68:560–566 (2007).


Choi YH, Love LB, Varner DD and Hinrichs K. Effect of holding technique and culture drop size in individual or group culture on blastocyst development after ICSI of equine oocytes with low meiotic competence. Animal Reprod. Sci., 102:38-47 (2007). Choi YH, Love LB, Varner DD and Hinrichs K. Holding immature equine oocytes in the absence of meiotic inhibitors: Effect on germinal vesicle chromatin and blastocyst development after intracytoplasmic sperm injection. Theriogenology 66:955-63 (2006). Hinrichs K, Choi YH, Love CC, Chung YG, Varner DD. Production of horse foals via direct injection of roscovitine-treated donor cells and activation by injection of sperm extract. Reproduction 131:1063-1072 (2006). Choi YH, Love CC, Varner DD and Hinrichs K Equine blastocyst development after intracytoplasmic injection of sperm subjected to two freeze-thaw cycles. Theriogenology 65:808-819 (2006). Choi YH, Love LB Varner DD and Hinrichs K. Blastocyst development in equine oocytes with low meiotic competence after suppression of meiosis with roscovitine prior to in vitro maturation. Zygote 14:1-8 (2006). Hinrichs K, Choi YH, Love LB, Varner DD, Love CC, and Walckenaer BE. Chromatin configuration within the germinal vesicle of horse oocytes: Changes post-mortem and relationship to meiotic and developmental competence. Biol. Reprod. 72:1142-50 (2005). Choi YH, Roasa LM, Love CC, Varner DD, Brinsko SP and Hinrichs K. Blastocyst formation rates in vivo and in vitro of in vitro-matured equine oocytes fertilized by intracytoplasmic sperm injection. Biol. Reprod. 70: 1231-1238 (2004). Bedford SJ, Kurokawa M, Hinrichs K, and Fissore RA. Patterns of intracellular calcium oscillations in horse oocytes fertilized by intracytoplasmic sperm injection: Possible explanations for the low success of this assisted reproduction technique in the horse. Biol. Reprod. 70:936-44 (2004). Choi YH, Love LB, Varner DD and Hinrichs K. Factors affecting developmental competence of equine oocytes after intracytoplasmic sperm injection. Reproduction 127:187-94 (2004). Choi YH, Love LB, Westhusin ME and Hinrichs K. Activation of equine nuclear transfer oocytes: methods and timing of treatment in relation to nuclear remodeling. Biol. Reprod. 70: 46-53 (2004). Choi YH, Love CC, Varner DD, Love LB and Hinrichs K. Effects of gas conditions, time of medium change, and ratio of medium to embryo on in vitro development of horse oocytes fertilized by intracytoplasmic sperm injection. Theriogenology 59:1219-1229 (2003). Franz LC, Choi YH, Squires EL, Seidel GE and Hinrichs K. Effects of roscovitine on maintenance of the germinal vesicle in horse oocytes, subsequent nuclear maturation, and cleavage rates after intracytoplasmic sperm injection. Reproduction 125:693-700 (2003). Willingham-Rocky LA, Hinrichs K, Westhusin ME, Kraemer DC. Effects of stage of oestrus cycle and progesterone supplementation during culture on maturation of canine oocytes in vitro. Reproduction 126:501-508 (2003). Dell’Aquila ME, Albrizio M, Maritato F, Minoia P and Hinrichs K. Meiotic competence of equine oocytes and rate of pronucleus formation after intracytoplasmic sperm injection (ICSI) as related to granulosa cell apoptosis. Biol. Reprod. 68:2065-2072 (2003). Bedford SJ, Kurokawa M, Hinrichs K and Fissore RA. Initiation of calcium oscillations and activation in horse oocytes injected with equine sperm extracts. Reproduction 126:489-99 (2003). Choi YH, Chung YG, Walker SC, Westhusin ME and Hinrichs K. In vitro development of equine nuclear transfer embryos: Effects of oocyte maturation media and amino acid composition during embryo culture. Zygote 11:77-86 (2003).


Love LB, Choi YH, Love CC, Varner DD and Hinrichs K. Effect of ovary storage and oocyte transport method on maturation rate of horse oocytes. Theriogenology 59:765-774 (2003). Choi YH, Love CC, Chung YG, Varner DD, Westhusin ME, Burghardt RC and Hinrichs K. Production of nuclear transfer horse embryos by Piezo-driven injection of somatic cell nuclei and activation with stallion sperm cytosolic extract. Biol. Reprod. 67:561-567 (2002). Love CC, Love LB, Varner DD and Hinrichs K. Effect of holding at room temperature after recovery on initial chromatin configuration and in vitro maturation rate of equine oocytes. Theriogenology 57:1973-1979 (2002). Hinrichs K, Love CC, Brinsko SP, Choi YH and Varner DD. In vitro fertilization of in vitro-matured equine oocytes: Effect of maturation medium, duration of maturation and sperm calcium ionophore treatment, and comparison with rates of fertilization in vivo after oviductal transfer. Biol. Reprod. 67: 256-262 (2002). Choi YH, Love CC, Love LB, Varner DD, Brinsko SP and Hinrichs K. Developmental competence in vivo and in vitro of in vitro-matured equine oocytes fertilized by intracytoplasmic sperm injection with fresh or frozen-thawed sperm. Reproduction 123: 455-465 (2002). Choi YH, Shin T, Love CC, Johnson C, Varner DD, Westhusin ME and Hinrichs K. Effect of co-culture with theca interna on nuclear maturation of horse oocytes with low meiotic competence, and subsequent fusion and activation rates after nuclear transfer. Theriogenology 57:1005-1011 (2002). Hinrichs K, Love CC, Choi YH, Varner DD, Wiggins CN and Reinoehl C. Suppression of meiosis by inhibitors of m-phase proteins in horse oocytes with low meiotic competence. Zygote 10:37-45 (2002). Dell’Aquila ME, Masterson M, Maritato F and Hinrichs K. Influence of oocyte collection technique on initial chromatin configuration, meiotic competence and male pronucleus formation after intracytoplasmic sperm injection (ICSI) of equine oocytes. Mol. Reprod. Devel. 60:79-88 (2001). Choi YH, Love CC, Thompson JA, Varner DD and Hinrichs K. Activation of cumulus-free horse oocytes: effect of maturation medium, calcium ionophore concentration and duration of cycloheximide exposure. Reproduction 122:177-183 (2001). Hinrichs K and Schmidt AL. Meiotic competence in horse oocytes: Interactions among chromatin configuration, follicle size, cumulus morphology and season. Biol. Reprod. 62:1402-1408 (2000). Hinrichs K, Provost PJ and Torello EM. Treatments resulting in pregnancy in nonovulating, hormone-treated oocyte recipient mares. Theriogenology 54:1285-1293 (2000). Bedford SJ, Gowdy LG and Hinrichs K. Comparison of longevity of motility of stallion spermatozoa incubated at 38oC in different capacitating media and containers. Theriogenology 51:637-646 (1999). Hinrichs K, Matthews GL, Freeman DA and Torello EM. Oocyte transfer in mares. J. Am. Vet. Med. Assoc. 212:982-986 (1998). Hinrichs K and Williams KA. Relationships among oocyte-cumulus morphology, follicular atresia and oocyte meiotic competence in the horse. Biol. Reprod. 57:377-384 (1997). Alm H and Hinrichs K. Effect of cycloheximide on nuclear maturation of horse oocytes and its relation to initial cumulus morphology. J. Reprod. Fertil. 107:215-220 (1996). Hawley LR, Enders AC and Hinrichs K. Comparison of equine and bovine oocyte-cumulus morphology within the ovarian follicle. Biol. Reprod. Mono. 1: 243-252 (1995). Hinrichs K, Schmidt AL and Selgrath JP. Activation of horse oocytes. Biol. Reprod. Mono. 1: 319-324 (1995).


Hinrichs K, Martin MG, Schmidt AL and Friedman PP. Effect of follicular components on meiotic arrest and resumption in horse oocytes. J. Reprod. Fertil. 104:149-156 (1995). Bedford S and Hinrichs K. The effect of insemination volume on pregnancy rates in pony mares. Theriogenology 42:571-578 (1994). Hinrichs K, Schmidt AL, Friedman PP, Selgrath JP and Martin MG. In vitro maturation of horse oocytes: Characterization of chromatin configuration using fluorescence microscopy. Biol. Reprod. 48:363-370 (1993). Hinrichs K, Spensley MS and McDonough PL. Evaluation of progesterone treatment to create a model for equine endometritis. Equine Vet. J. 23:457-461 (1992). Hinrichs K and DiGiorgio LM. Embryonic development after intrafollicular transfer of immature horse oocytes. J. Reprod. Fertil. Suppl. 44:369-374 (1991). Hinrichs K. The relationship of follicle atresia to follicle size, oocyte recovery rate on aspiration, and oocyte morphology in the mare. Theriogenology 36:157-168 (1991). Hinrichs K, Rand WM and Palmer E. Effect of aspiration of the preovulatory follicle on luteinization, corpus luteum function, and peripheral plasma gonadotropin concentrations in the mare. Biol. Reprod. 44:292-298 (1991). Hinrichs K and Watson ED. Effect of administration of phenylbutazone or progesterone on recovery of embryos from the uterus 5 days after ovulation in mares. Am. J. Vet. Res. 52:678-681 (1991). Hinrichs K, Schmidt AL, Memon MA, Selgrath JP and Ebert KM. Culture of 5-day horse embryos in microdroplets for 10 to 20 days. Theriogenology 34:643-654 (1990). Hinrichs K, Kenney DF and Kenney RM. Aspiration of oocytes from mature and immature pre-ovulatory follicles in the mare. Theriogenology 34:107-112 (1990). Hinrichs K and Riera FL. Effect of administration of prostaglandin F2 alpha on embryo recovery from the uterus on day 5 after ovulation in mares. Am. J. Vet. Res. 51:451-453 (1990). Hinrichs K and Hunt PR. Ultrasound as an aid to diagnosis of granulosa cell tumor in the mare. Equine Vet. J. 22:99-103 (1990). Hinrichs K, Riera FL and Klunder LR. Establishment of pregnancy after embryo transfer in mares with gonadal dysgenesis. J. In Vitro Fertilization Embryo Transfer 6:305-309 (1989). Watson ED and Hinrichs K. Adrenal production of sex steroids in the mare. Theriogenology 32:913-919 (1989). Sertich PL, Hinrichs K and Kenney RM. Histological aspects of uterine involution of the postparturient, ovariectomised, embryo-recipient mare: a model for the study of involution. Equine Vet. J. Suppl. 8:56-58 (1989). Hinrichs K, Sharp DC and Kenney RM. Differences in protein content of uterine fluid related to duration of progesterone treatment in ovariectomised mares used as embryo transfer recipients. Equine Vet. J. Suppl. 8:49-55 (1989). Watson ED and Hinrichs K. Effect of prostaglandin F2 alpha on adrenal-produced steroid hormones in the cow. Am. J. Vet. Res. 50:1078-1079 (1989). Watson ED and Hinrichs K. Changes in concentrations of steroids and prostaglandin F in preovulatory follicles of the mare after administration of hCG. J. Reprod. Fertil. 84:557-561 (1988).


Hinrichs K, Cummings MR, Sertich PL and Kenney RM. Clinical significance of aerobic bacterial flora from the uterus, vagina, vestibule and clitoral fossa of clinically normal mares. J. Am. Vet. Med. Assn. 193:72-75 (1988). Sertich PL, Hinrichs K, Schiereck DE and Kenney RM. Periparturient events in ovariectomized embryo transfer recipient mares. Theriogenology 30:401-409 (1988). Hinrichs K, Sertich PL, Solorzano NM and Caldwell LA. Use of an immediate, qualitative progesterone assay for determination of day of ovulation in an equine embryo transfer program. Theriogenology 29:1123-1130 (1988). McDonnell SM, Hinrichs K, Cooper WL and Kenney RM. Use of an androgenized mare as an aid in detection of estrus in mares. Theriogenology 30:547-553 (1988). Hinrichs K and Kenney RM. Effect of timing of progesterone administration on pregnancy rate after embryo transfer in ovariectomized mares. J. Reprod. Fertil. Suppl. 35:439-443 (1987). Hinrichs K, Sertich PL, Palmer E, and Kenney RM. Establishment and maintenance of pregnancy after embryo transfer in ovariectomized mares treated with progesterone. J. Reprod. Fertil. 80:395-401 (1987). Hinrichs K, Sertich PL, and Kenney RM. Use of altrenogest to prepare ovariectomized mares as embryo transfer recipients. Theriogenology. 26:455-460 (1986). Van Huffel XM, Varner DD, Hinrichs K, Garcia MC, Strzemienski PJ, and Kenney RM. Photomicrographic evaluation of stallion spermatozoal motility characteristics. Am. J. Vet. Res. 46:1272-1275 (1985). Varner DD, Hinrichs K, Garcia MC, Osborne HG, Blanchard TL, and Kenney RM. A comparison between the cervical dimensions of pregnant and non-pregnant Santa Gertrudis and Bos taurus cows. Theriogenology. 24:109-118 (1985). Publications in refereed journals: Clinical reports Mancill SS, Blodgett G, Arnott RJ, Alvarenga M, Love CC and Hinrichs K. Description and genetic analysis of three sets of monozygotic twins resulting from transfers of single embryos to recipient mares. J. Am. Vet. Med. Assoc 238:1040-1043 (2011). Hinrichs K, Buoen LC and Ruth GR. XX/XY chimerism and freemartinism in a female llama co-twin to a male. J. Am. Vet. Med. Assoc. 215:1140-1141 (1999). Hinrichs K, Provost PJ and Torello EM. Birth of a foal after oocyte transfer to a nonovulating, hormone-treated mare. Theriogenology 51:1251-1258 (1999). Hinrichs K, Horin SE, Buoen LC, Zhang TQ and Ruth GR. X-chromosome monosomy in an infertile female llama. J. Am. Vet. Med. Assoc. 210:1503-1504 (1997). Bedford SJ, Hawes M, Paradis MR, Mort JD and Hinrichs K. Peritonitis associated with passage of the placenta into the abdominal cavity in a llama. J. Am. Vet. Med. Assoc. 209:1914-1916 (1996). Hinrichs K, Cochran SL, Schelling SH, and Steckel RR. Granulosa-theca cell tumor associated with an ovulation fossa and normal ovarian stroma in a mare. J. Am. Vet. Med. Assoc. 200:696-698 (1992). Hinrichs K, Watson ED and Kenney RM. Granulosa cell tumor in a mare with a functional contralateral ovary. J. Am. Vet. Med. Assoc. 197:1037-1038 (1990). Riera FL, Hinrichs K, Hunt PR and Kenney RM. Cervical hyperplasia with prolapse in a mare. J. Am. Vet. Med. Assoc. 195:1393-1394 (1989).


Hinrichs K, Frazer GS, deGannes RVG, Richardson DW and Kenney RM. Serous cystadenoma with elevated plasma testosterone levels in a normally cyclic mare. J. Am. Vet. Med. Assoc. 194:381-382 (1989). Hinrichs K and Watson ED. Recovery of a degenerating 14-day embryo on uterine flush 7 days after ovulation in a mare. Theriogenology 30:349-353 (1988). Hinrichs K, Gentile DG, Hurtgen JP, and Richardson DW. Complications from a testicular prosthesis in a stallion. J. Am. Vet. Med. Assoc. 186:390-391 (1985). Hinrichs K, Hurtgen JP, and Kenney RM. Unilateral hydrosalpinx and absence of the infundibulum in a mare. Theriogenology 22:571-577 (1984). Hinrichs K and Kenney RM. Infertility due to foreign objects in the cervix of a cow. J. Am. Vet. Med. Assoc. 185:788-789 (1984). Brown JS, Varner DD, Hinrichs K, and Kenney RM. Surgical repair of the lacerated cervix in the mare. Theriogenology 22:351-359 (1984). Reviews and Book Chapters Johnson AK and Hinrichs K. Health and neonatal care of foals derived by use of somatic cell nuclear transfer. In: Cell Reprogramming Protocols; Induced Pluripotency and Nuclear Transfer. Methods in Molecular Biology Series, Humana Press – Springer, New York, NY (in press). Hall V, Hinrichs K, Lazzari G, Betts D and Hyttel P. Embryo technology and stem cell biology in domestic mammals (Review). Vet. J. 197:128-142 (2013). Hinrichs K. Assisted reproduction techniques in the horse (Review). Reprod. Fertil. Dev. 25:80-93 (2012). Hinrichs K and Loux SC. Hyperactivated sperm motility: Are equine sperm different? (Review). Proceedings, 6th International Symposium on Stallion Reproduction. J. Equine Vet. Sci. 32:441-444 (2012). Hinrichs K and Choi YH. Equine embryo biopsy, genetic testing, and cryopreservation (Review). J. Equine Vet. Sci. 32:390-396 (2012). Dell’Aquila ME, Goudet G, Cho YS, Martino NA, Uranio MF, Rutigliano L and Hinrichs K. OMICS for the identification of biomarkers for oocyte competence, with special reference to the mare as a prospective model for human reproductive medicine. In: Meiosis, Swan A, ed. InTech, Rijeka, Croatia; ISBN 978-953-51-0118-5. www.inechopen.com/articles/show/title/omics-for-the-identification-of-biomarkers-for-oocyte-competence-with-special-reference-to-the-mare- (2012). Hinrichs K. Biopsy and vitrification of expanded equine blastocysts (Review). Proceedings, Soc. Theriogenology, pp.314–317 (2011). Hinrichs K. Biotechnology in equine reproduction (Review). Proceedings, IX National Congress, Società Italiana di Riproduzione Animale (Italian Society of Animal Reproduction); http://www.societaitalianariproduzioneanimale.it (2011). Velez IC, Hinrichs K. Técnicas de reproducción asistida en caballos (Review). Rev. CES Med. Zootec. 6:124-128 (2011). Hinrichs K. Immature oocyte collection and maturation. In: Equine Reproduction (2nd Edition), McKinnon AO, Squires EL, Vaala W and Varner DD, eds. Blackwell Publishing, Malden, MA, pp. 2931-2935 (2011).


Hinrichs K. Nuclear transfer. In: Equine Reproduction (2nd Edition), McKinnon AO, Squires EL, Vaala W and Varner DD, eds. Blackwell Publishing, Malden, MA, pp. 2924-2927 (2011). Choi YH and Hinrichs K. Intracytoplasmic sperm injection. In: Equine Reproduction (2nd Edition), McKinnon AO, Squires EL, Vaala W and Varner DD, eds. Blackwell Publishing, Malden, MA, pp. 2948-2952 (2011). Hinrichs K. Application of assisted reproductive technologies (ART) to clinical practice (Review). Proceedings, Am. Assoc. Equine Pract. 195-206 (2010). Hinrichs K. The equine oocyte: factors affecting meiotic and developmental competence (Review). Molec. Reprod. Devel. 77: 651-661 (2010). Hinrichs K. Cloning of domestic animals. In: The Merck Veterinary Manual, 10th Edition. Merck and Co., Inc., Rahway, NJ, pp. 1834-1838 (2010). Hinrichs K. In vitro production of equine embryos: state of the ART (Review). Reprod. Domestic Anim. 45;Suppl 2:3-8 (2010). Hinrichs K. Assisted reproductive technology. In: Manual of Equine Reproduction (3rd Edition), Blanchard TL, Varner DD, Schumacher J, et al., eds. Mosby-Year Book, Inc., St. Louis, MO, pp. 302-312 (2010). Hinrichs K. Irregularities of the Estrus Cycle and Ovulation in Mares (including Seasonal Transition). In: Current Therapy in Large Animal Theriogenology 2, Youngquist RS and Threlfall WR, eds., Saunders Elsevier, St. Louis, MO, pp. 144-152 (2007). Hinrichs K. Equine Cloning. In: Veterinary Clinics of North America: Equine Practice, Carnevale EM, ed., W.B. Saunders Co., Philadelphia, PA, pp. 857-866 (2006). Hinrichs K. In vitro fertilization; In vitro oocyte maturation. In: Current Therapy in Equine Reproduction, Samper J, Pycock J and McKinnon AO, eds. Saunders Elsevier, St. Louis, MO, pp. 308-309; 310-314 (2006). Hinrichs K. A review of cloning in the horse. (Review) Proceedings, Am. Assoc. Equine Pract, pp. 398-401 (2006). Hinrichs K and Choi YH. Assisted Reproductive Techniques in the Horse. In: Clinical Techniques in Equine Practice 4 (3): Equine Reproduction. Elsevier, Philadelphia, PA pp 210-218 (2005). Hinrichs K. An update on equine ICSI and cloning. (Review) Theriogenology. 64:535-41 (2005) Hinrichs K. Breeding soundness examination in the male; Embryo transfer in farm animals; Hormonal control of estrus. In: The Merck Veterinary Manual, 9th Edition. Merck and Co., Inc., Rahway, NJ pp 1797-1811 (2005). Westhusin ME, Hinrichs K, Choi YH, Shin T, Liu L and Kraemer D. Cloning Companion Animals (Horses, Cats, and Dogs). (Review) Cloning Stem Cells 5: 301-317 (2003). Hinrichs K. Current status and clinical potential of IVF, ICSI and cloning in horses. (Review) Proceedings, Soc. Theriogenology, pp. 133-141 (2002). Hinrichs K. Embryo production by assisted reproduction in the horse. (Review). Theriogenology 49:13-21 (1998). Hinrichs K. Breeding soundness examination in the male; Embryo transfer in farm animals; Hormonal control of estrus. In: The Merck Veterinary Manual, 8th Edition. Merck and Co., Inc., Rahway, NJ. pp. 1508-1520 (1998). Hinrichs K. Theriogenology. In: Review Questions and Answers for Veterinary Boards, Small Animal Medicine and Surgery, 2nd Edition, Pratt PW, ed. Mosby-Year Book, Inc., Santa Barbara, CA pp277-281 (1998).


Hinrichs K. Cumulus expansion, chromatin configuration and meiotic competence in horse oocytes. (Review). Equine Vet. J. Suppl. 25:43-46 (1997). Hinrichs K. Irregularities of the estrus cycle and ovulation in the mare. In: Current Therapy in Theriogenology III: Large Animal, Youngquist RS, ed., W.B. Saunders Co., Philadelphia, PA pp. 166-171 (1997). Hinrichs K. Assisted reproductive techniques in the mare. In: Current Therapy in Equine Medicine 4, Robinson NE, ed., W.B. Saunders Co., Philadelphia. pp. 565-571 (1997). Hinrichs K, Matthews GL, Freeman DA and Torello EM. Oocyte transfer as a clinical procedure in the mare. (Review). Proceedings, Am. Assoc. Equine Pract., pp. 187-188 (1997). Hinrichs K. Oocyte collection and maturation. (Review). Proceedings, Soc. Theriogenology, pp. 147-151 (1997). Hinrichs K. Manipulation of oocyte maturation in vitro. (Review). Archiv fur Tierzucht., Dummerstorf (Special Issue) 39:43-50 (1996). Hinrichs K. Assisted reproductive technology in the horse. (Review). Proceedings, Soc. Theriogenology, pp.162-173 (1994). Hinrichs K. Use of ovariectomized mares as embryo transfer recipients and Future technology: oocyte transfer, maturation and in vitro fertilization. (Review). Ars Veterinaria 10 (Suppl.): 89-98 (1994). Hinrichs K, Schmidt AL and Selgrath JP. Atlas of chromatin configurations of germinal vesicle stage and maturing horse oocytes. (Review). Equine Vet. J. Suppl. 15:60-63 (1993). Hinrichs K. Embryo transfer in the mare: a status report. (Review). In: Current Advances in the Manipulation of Reproductive Functions in Domesticated Species of Animals, Anim. Reprod. Sci., 33:227-240 (1993). Hinrichs K. Potential for gamete manipulation in the horse: GIFT, IVF and embryo transfer. (Review). Proceedings, Soc. Theriogenology, pp. 14-17 (1992). Hinrichs K. Ultrasonographic techniques in mare reproduction. (Review). Proceedings, Am. College of Theriogenologists Equine Theriogenology Short Course, pp. 92-94 (1992). Hinrichs K. Effect of cumulus morphology on maturation of horse oocytes in vitro / Wspolzaleznosc pomiedzy wygladem morfologicznym komorek wzgorka, a dojrzewaniem in vitro oocytow klaczy. (Review). Proceedings, Int. Scientific Conference on Biotechnics in Horse Reproduction, Agricultural University of Crakow, pp. 18-19 / 21-22 (1992). Hinrichs K. Prospects for oocyte aspiration, fertilization and transfer in the horse. (Review). Proceedings, Am. Assoc. Equine Pract. pp. 189-196 (1992). Hinrichs K. Embryo transfer in the mare. In: Current Therapy in Equine Medicine 3, Robinson NE, ed., W.B. Saunders Co., Philadelphia; pp. 637-642. (1991). Hinrichs K. Ultrasonographic assessment of ovarian abnormalities. (Review) Proceedings, Am. Assoc. Equine Pract., pp. 31-40 (1991). Freeman DE and Hinrichs K. Granulosa cell tumor. In: Current Practice of Equine Surgery, White NA and Moore JN, eds. JB Lippincott Co., Philadelphia; pp. 711-716 (1990). Hinrichs K. Use of ovariectomized, progestogen treated mares as embryo transfer recipients. (Review) Proceedings, Soc. Theriogenology, pp. 107-110 (1986).


Non-refereed publications, proceedings, and abstracts Choi YH, Velez IC, Macías-García B, Hinrichs K. Effect of oocyte maturation duration on blastocyst rates after equine somatic cell nuclear transfer (Abstract). Reprod. Fertil. Dev.27:112 (2014). Martino NA, Dell'Aquila ME, Uranio MF, Lampignano R, Lacalandra GM, Hinrichs K. Temperature during overnight holding in meiosis inhibitor-free medium affects chromatin configuration and meiotic resumption in equine oocytes (Abstract). Reprod. Fertil. Dev.27:244 (2014). Choi YH, Velez IC, Macías-García B and Hinrichs K. Effect of early medium pH on equine embryo development in vitro after intracytoplasmic sperm injection (Abstract). Clinical Theriogenology 6:379 (2014) Vivani L, Love CC, Varner DD and Hinrichs K, The effect of zinc on stallion sperm motility (Abstract). J. Equine Vet. Sci. 34:44 (2014). Loux SC, González-Fernández L, Macías-García B, Varner DD and Hinrichs K. The effect of calcium, pH and motility factors on the axoneme of demembranated stallion spermatozoa (Abstract). J. Equine Vet. Sci. 34:45 (2014). Hinrichs K, Choi YH, Love CC and Spacek S. Use of in vitro maturation of oocytes, intracytoplasmic sperm injection and in vitro culture to the blastocyst stage in a commercial equine assisted reproduction program (Abstract). J. Equine Vet. Sci. 34:176 (2014). Choi YH, Velez IC, Macías-García B and Hinrichs K. Effect of activation and reconstruction timing on blastocyst rates in equine somatic cell nuclear transfer (Abstract). J. Equine Vet. Sci. 34:179 (2014). Choi YH, Ritthaler J and Hinrichs K. Production of a cloned foal using mitochondrial DNA-identical oocytes (Abstract). Reprod. Fertil. Dev. 26:131 (2014) Choi YH, Velez IC, Macías-García B, Riera FL, and Hinrichs K.Effect of medium and medium glucose concentration on equine embryo development after intracytoplasmic sperm injection (Abstract). Clin. Theriogenology 5:405 (2013). Vivani L, Love CC, Hinrichs K, Blanchard TL, Brinsko SP and Varner DD. Effect of atmospheric conditions on protein tyrosine phosphorylation in stallion sperm (Abstract). J. Equine Vet. Sci. 32:517-518 (2012). Filioli Uranio M, Dell’Aquila ME, Martino NA, and Hinrichs K. Holding in meiosis inhibitor-free medium does not affect oxidative status and development (Abstract). Proceedings, Ovarian Club Forum II; http://www.comtecmed.com/ OC/2012/poster_list.aspx (2012). Choi YH, Velez IC, Macías-García B, Spacek S and Hinrichs K. Effect of antibiotic treatment of mares prior to transvaginal follicle aspiration on embryo development after in vitro oocyte maturation and intracytoplasmic sperm injection (Abstract). Clin. Theriogenology 4:428 (2012). Macías-García B, González-Fernández L, Loux SC, Varner DD and Hinrichs K. Calmodulin, calmodulin kinase II and extracellular calcium are implicated in control of hyperactivated motility in stallion sperm (Abstract). Reprod. Dom. Anim. 47 (Suppl. 5):95 (2012). Choi YH, Velez IC, Macías-García B, Spacek S, Norris JD, Hinrichs K. Factors affecting equine embryo development after post-mortem ICSI in a clinical program (Abstract). J. Equine Vet. Sci. 32:409-410 (2012). Riera FL, Roldán JE, Grunwaldt M, Velez IC, Choi YH and Hinrichs K. From commercial embryo transfer to assisted reproduction technology (Abstract). J. Equine Vet. Sci. 32:404 (2012). Choi YH, Penedo C, Velez IC and Hinrichs K. Accuracy of preimplantation genetic diagnosis using cells biopsied from equine blastocysts. (Abstract). Reprod. Fertil. Dev. 24:163-164 (2012).


Hinrichs K. Sporadic success of equine in vitro fertilization amid consistent failure – What happened? (Abstract). Proceedings, Havemeyer Foundation Workshop on Equine In Vitro Fertilization,pp. 5-6 (2011). Choi YH and Hinrichs K. Progress in the use of intracytoplasmic sperm injection in the horse (Abstract). Proceedings, Havemeyer Foundation Workshop on Equine In Vitro Fertilization, p. 18 (2011). Dell’Aquila ME, Filioli Uranio M, Martino NA, and Hinrichs K. Effects of holding oocytes in the absence of meiosis inhibitors on intracellular levels of reactive oxygen species and in vitro embryo development in the mare (Abstract). Proceedings, Ovarian Club Forum I; http://www.comtecmed.com/OC/2011/poster_list.aspx (2011). Dell’Aquila ME, Lacalandra GM, Ambruosi B, Filioli Uranio M, Martino NA, Nicassio M, Minoia R, Fusiello N, Hinrichs K. Effects of ovary storage and oocyte holding in the absence of meiosis inhibitors on in vitro embryo development in the mare (Abstract). Proceedings, IX National Congress, Società Italiana di Riproduzione Animale (Italian Society of Animal Reproduction): p. 84-87 (2011). Choi YH, Norris JD, Velez IC, Jacobson CC, Hartman DL and Hinrichs K. A cloned foal produced using oocytes recovered by transvaginal aspiration of immature follicles (Abstract). Reprod. Fertil. Dev. 23:122 (2011). Velez IC, Norris JD, Choi YH, Loux S and Hinrichs K. Effect of holding aspirated fluid from immature equine follicles on oocyte maturation and blastocyst production after intracytoplasmic sperm injection (Abstract). Reprod. Fertil. Dev. 23:235 (2011). Choi YH, Norris JD, Velez IC, Jacobson CC, Hartman DL and Hinrichs K. Use of metaphase I oocytes or a histone deacetylase inhibitor in equine nuclear transfer. (Abstract) Anim. Reprod. Sci. 121 (Suppl 1-2): 311 (2010). Hinrichs K, Choi YH, Norris JD, Love LB, Bedford-Guaus SJ, Hartman DL and Velez IC. Use of intracytoplasmic sperm injection and in vitro culture to the blastocyst stage for clinical production of foals post mortem. (Abstract) Anim. Reprod. Sci. 121 (Suppl 1-2): 239-240 (2010). Loux SC, Crawford KR, Norris JD, Ing NH, Reynolds EA, Love CC, Varner DD, Velez IC, Dangott LJ, Thornton ER, Choi YH and Hinrichs K. The CatSper ion channel and hyperactivated motility of equine spermatozoa. (Abstract) Anim. Reprod. Sci. 121 (Suppl 1-2): 180 (2010). Velez IC, Norris JD, Ballard K, Lassell K, Choi YH and Hinrichs K. Effect of method of overnight shipment of oocytes or ovaries on blastocyst formation after intracytoplasmic sperm injection. (Abstract) Anim. Reprod. Sci. 121 (Suppl 1-2):244 (2010). Hayden SS, Blanchard TL, Brinsko SP, Varner DD, Hinrichs K and Love CC. Low-dose deep-horn insemination: a comparison of transrectally guided and hysteroscopic techniques (Abstract) Anim. Reprod. Sci. 121 (Suppl 1-2):155 (2010). Choi YH, Hartman DL, Bliss SB, Hayden SS, Blanchard TL and Hinrichs K. High pregnancy rates after transfer of large equine blastocysts collapsed via micromanipulation before vitrification (Abstract) Reprod. Fertil. Dev. 22:203 (2010). Hinrichs K. Equine ICSI: History and current status. (Abstract) Reprod. Domestic Anim. 44: 62 (2009). Commaille LF, Vogelsang MM, Sigler DH and Hinrichs K. Intrauterine temperature of mares under different management conditions (Abstract) J. Equine Vet. Sci. Vol 29: 344-345(2009). Choi YH, Hartman DL and Hinrichs K. Viability of equine blastocysts subjected to biopsy for pre-implantation genetic diagnosis. (Abstract) Reprod. Fertil. Dev. 21:166-167 (2009).


Mancill SS, Arnott RJ, Love CC and Hinrichs K. Monozygotic twins after embryo transfer, verified by DNA typing. (Abstract) Proceedings, Am. Assoc. Equine Pract., p. 278 (2008). McPartlin LA, Suarez SS, Czaya CA, Hinrichs K and Bedford-Guaus SJ. Hyperactivation of stallion sperm is required for successful in vitro fertilization of equine oocytes. (Abstract) Proceedings, Soc. Study Reprod., p. 206 (2008). Hinrichs K, Choi YH, Harding HD, Obermiller AD and Hartman DL. Oct-4 expression in in vivo and in vitro-produced equine blastocysts. (Abstract) Proceedings, 7th International Symposium on Equine Embryo Transfer, Havemeyer Foundation, p. 46 (2008). Choi YH, Hartman DL, Fissore RA, Bedford SJ and Hinrichs K. Activation methods associated with cloning efficiency in the horse. (Abstract) Proceedings, 7th International Symposium on Equine Embryo Transfer, Havemeyer Foundation, pp. 26-27 (2008). Riera FL, Roldan JE and Hinrichs K. Pregnancy rate after embryo transfer in ovulating versus progesterone treated-anestrous recipient mares in a commercial embryo transfer programme. (Abstract) Proceedings, 7th International Symposium on Equine Embryo Transfer, Havemeyer Foundation, pp. 79-80 (2008). Alm H, Choi YH, Love L, Heleil B, Torner H, Hinrichs K. Effect of holding technique of bovine oocytes before in vitro maturation on their further blastocyst development in vitro. (Abstract) Reprod. Domestic Anim. 43: Suppl. 1, p 3 (2008). Choi YH, Hartman DL, Fissore RA, Bedford SJ and Hinrichs K. Effect of activation methods and biopsy sample on nuclear transfer blastocyst production and cloning efficiency in a horse. (Abstract) Reprod. Fertil. Devel. 20:94 (2008). Choi YH, Harding HD, Obermiller AD, and Hinrichs K. Oct-4 expression pattern in the equine embryo. (Abstract) Reprod. Fertil. Devel. 19:189-190 (2007). Choi YH, Varner DD, Hartman DL and Hinrichs K. Blastocyst production from equine oocytes fertilized by intracytoplasmic injection of lyophilized sperm. (Abstract) Anim. Reprod. Sci. 94:307-308 (2006). Petersen MM, Choi YH, Brück Bøgh I, and Hinrichs K. Incubation of equine oocytes in roscovitine before in vitro maturation: Influence of maturation time before fertilization. (Abstract) Anim. Reprod. Sci 94:362-363 (2006). Hinrichs K, Choi YH, Varner DD, and Hartman DL. Efficient production of cloned horse pregnancies using roscovitine-treated donor cells. (Abstract) Anim. Reprod. Sci 94:309-310 (2006). Varner DD, Love CC, Choi YH, Teague S, Thompson JA and Hinrichs K. Effect of multiple lyophilization or freeze-thaw cycles on chromatin quality of stallion sperm. (Abstract) Anim. Reprod. Sci 94:19-20 (2006). Riera FL, Roldán JE and Hinrichs K. Patterns of embryo recovery in mares with unilateral and bilateral double ovulations. (Abstract). Anim. Reprod. Sci 94:398-399 (2006). Mortensen C, Choi YH, Hinrichs K, Ing N, Kraemer D, Vogelsang S and Vogelsang M. Effects of exercise on embryo recovery rates and embryo quality score in the horse. (Abstract) Anim. Reprod. Sci 94:395-397 (2006). Hinrichs K, Choi YH, Hartman DL and Varner DD. Blastocysts, pregnancies and foals from ICSI and nuclear transfer. (Abstract) Proceedings, 4th Meeting of the International Equine Gamete Group, Havemeyer Foundation Monograph 18: 45-46 (2006). Varner DD, Love CC, Choi YH and Hinrichs K. Exposure of stallion semen to two freeze-thaw cycles: Effects on spermatozoal viability. (Abstract) Proceedings, 4th Meeting of the International Equine Gamete Group Havemeyer Foundation Monograph 18: 15-16 (2006). Choi YH, Love CC, Varner DD and Hinrichs K. Equine embryo development after intracytoplasmic fertilization


with twice frozen-thawed sperm. (Abstract) Proceedings, 4th Meeting of the International Equine Gamete Group Havemeyer Foundation Monograph 18: 19-20 (2006). Choi YH, Chung YG, Varner DD and Hinrichs K. Birth of a cloned foal by adult somatic cell nuclear transfer with roscovitine-treated donor cells. (Abstract) Reprod. Fertil. Dev. 18:123 (2006). Hinrichs K, Choi YH, Love LB, and Varner DD. Transfer of in vitro-produced equine embryos. (Abstract) Proceedings, 6th International Syposium on Equine Embryo Transfer, Havemeyer Foundation, p. 38-39 (2005). Riera FL, Roldán JE and Hinrichs K. Ipsilateral double ovulation is associated with reduced embryo recovery in mares. (Abstract) Proceedings, 6th International Equine Embryo Transfer Symposium, Havemeyer Foundation, p. 108-109 (2005). Choi YH, Love LB, Varner DD and Hinrichs K. Blastocyst development of equine oocytes with low meiotic competence held in roscovitine before in vitro maturation. (Abstract) Reprod. Fertil. Dev. p. 216-217 (2005). Pryor J, Romo S, Varner DD, Hinrichs K and Looney CR. Comparison of two sperm separation products for use in bovine IVF. (Abstract) Reprod. Fertil. Dev. p. 277 (2005). Romo S, Pryor J, Varner DD, Hinrichs K and Looney CR. Comparison of three different IVF protocols for bovine oocytes. (Abstract) Reprod. Fertil. Dev. p. 276 (2005). Hinrichs K, Choi YH, Walckenaer BE and Varner DD. Interactions between time of oocyte recovery (immediate vs delayed) and duration of in vitro maturation on developmental competence of horse oocytes. (Abstract) Proceedings, Havemeyer Foundation Workshop: Transporting Gametes and Embryos p. 5-6 (2004). Bedford SJ, Hinrichs K and Fissore RA. Oocyte maturation and effect on sperm or sperm extract induced intracellular calcium oscillations. (Abstract) Proceedings, Havemeyer Foundation Workshop: Transporting Gametes and Embryos p. 9-10 (2004). Choi YH, Roasa LM, Varner DD, Hinrichs K. Blastocyst development of in vitro- and in vivo-matured equine oocytes fertilised by ICSI. (Abstract) Proceedings, Havemeyer Foundation Workshop: Transporting Gametes and Embryos p. 29-30 (2004). Choi YH, Varner DD and Hinrichs K. Comparison of embryo culture media for blastocyst development after intracytoplasmic sperm injection of in vitro-matured equine oocytes. (Abstract) Reprod. Fertil. Dev. 16:195 (2004). Hinrichs K, Choi YH, Love CC, Varner DD, Brinsko SP and Love LB. Relationships between equine oocyte characteristics and developmental potential. (Abstract) Proceedings, Havemeyer Foundation Workshop: From Epididymis to Embryo p. 48-49 (2003). Choi YH, Love CC, Love LB, Varner DD and Hinrichs K. Techniques for achieving fertilization in vitro in the horse. (Abstract) Proceedings, Havemeyer Foundation Workshop: From Epididymis to Embryo p. 64-65 (2003). Choi YH, Love CC, Chung YG, Varner DD, Westhusin ME, Burghardt RC and Hinrichs K. Use of Piezo-driven direct nuclear injection and activation with stallion sperm extract to produce horse nuclear transfer embryos. (Abstract) Theriogenology 58:771-774 (2002). Bedford SJ, Kurokawa M, Hinrichs K and Fissore RA. Patterns of [Ca2+]i oscillations after intracytoplasmic sperm injection of in vitro and in vivo matured horse oocytes. (Abstract) Theriogenology 58:701-704 (2002). Hinrichs K, Choi YH, Love LB, Love CC, Varner DD and Ingram LA. Effect of holding time and media on meiotic and developmental competence of horse oocytes. (Abstract) Theriogenology 58:675-678 (2002). Franz LC, Choi YH, Squires EL, Seidel GE and Hinrichs K. Effect of transient suppression of meiosis with roscovitine on subsequent developmental competence of equine oocytes. (Abstract) Biol. Reprod. 66; Suppl.1:175-176 (2002).


Riera FL, Roldán JE, Love CC and Hinrichs K. Effect of stallion on embryo recovery, quality, and stage, and on pregnancy rate after transfer, in a commercial embryo transfer program. (Abstract) Proceedings, Havemeyer Foundation Workshop on Advanced Clinical Topics in Stallion Reproduction. Bedford SJ, Kurokawa M, Hinrichs K and Fissore R. Activation and intracellular calcium ([Ca2+]I) transients induced by microinjection of equine sperm factor on murine and equine oocytes. (Abstract) Theriogenology 57:699 (2002). Alm H, Hinrichs K, Torner H and Kanitz W. Evaluation of germinal vesicle status in horse oocytes using different staining methods. (Abstract) Proceedings, 5th Annual Conference European Society for Domestic Animal Reproduction, p.48 (2001). Choi YH, Love CC, Love LB, Varner DD, Brinsko SP and Hinrichs K. In vitro and in vivo development of in vitro-matured horse oocytes fertilized by intracytoplasmic sperm injection. (Abstract) Proceedings, Soc. Theriogenology, p.8 (2001). Dell’Aquila ME, Masterson M, Maritato F and Hinrichs K. Chromatin configuration, meiotic competence and success of intra-cytoplasmic sperm injection in horse oocytes collected by follicular aspiration or scraping. (Abstract) Proceedings, 5th International Symposium on Equine Embryo Transfer, Havemeyer Foundation, T. Katila and J. Wade, eds. pp. 37-38 (2001). Hinrichs K, Shin TS, Love CC, Varner DD and Westhusin M. Comparison of bovine and equine oocytes as host cytoplasts for equine nuclear transfer. (Abstract) Proceedings, 5th International Symposium on Equine Embryo Transfer, Havemeyer Foundation, T. Katila and J. Wade, eds. pp. 43-44 (2001). Love CC, Brinsko SP, Varner DD and Hinrichs K. Fertilisation rates of in vitro-matured oocytes transferred into the oviduct of inseminated mares. (Abstract) Proceedings, 5th International Symposium on Equine Embryo Transfer, Havemeyer Foundation, T. Katila and J. Wade, eds. pp. 41-42 (2001). Riera FL, Roldán JE, and Hinrichs K. Effect of insemination timing on embryo recovery rate, pregnancy rate after transfer, and pregnancy loss rate in a commercial embryo transfer programme. (Abstract) Proceedings, 5th International Symposium on Equine Embryo Transfer, Havemeyer Foundation, T. Katila and J. Wade, eds. pp. 89-90 (2001). Choi YH, Shin T, Love CC, Burghardt RC, Varner DD and Hinrichs K. Effects of initial cumulus morphology and addition of cytochalasin B on fusion, activation and cleavage of horse oocytes undergoing nuclear transfer. (Abstract) Theriogenology 55:261 (2001). Hinrichs K, Shin TS, Love CC, Varner DD and Westhusin M. Production of equine embryos by nuclear transfer: comparison of efficiency of equine and bovine cytoplasts. (Abstract) Proceedings, Soc. Theriogenology, p.133 (2000). Dell’Aquila ME, Albrizio M, Lacalandra GM, Maritato F, Hinrichs K and Minoia P. Follicular wall apoptosis and pronuclear formation in equine oocytes submitted to intracytoplasmic sperm injection (ICSI) [Apoptosi follicolare e formazione dei pronuclei in ovociti equini sottoposti ad iniezione intracitoplasmatica dello spermatozoo (ICSI)]. (Abstract) Proceedings, LIV Congresso Società Italiana Scienze Veterinarie; vol LIV: pp.127-128 (2000). Kanitz W, Alm H, Becker F, Nurnberg G, Kurth J and Hinrichs K. Repeated follicular aspiration in mares: consequences for follicular growth and oocyte quality. (Original research report) J. Reprod. Fertil. Suppl. 56:463-472 (2000). Hinrichs K, Betschart RW, McCue PM and Squires EL. Effect of time of follicle aspiration on pregnancy rate after oocyte transfer in the mare. (Original research report) J. Reprod. Fertil. Suppl. 56:493-498 (2000). Hinrichs K, Provost PJ and Torello EM. Use of non-ovulating, hormone-treated mares as oocyte transfer recipients. (Abstract) Proceedings, Soc. Theriogenology, p. 43 (1999).


Alm H, Torner H, Kanitz W, Becker F and Hinrichs K. Comparison of different methods for recovery of horse oocytes. (Original Report). Equine Vet. J. Suppl. 25:47-50 (1997). Hinrichs K, Matthews GL and Freeman DA. Effect of oocyte maturation time on embryo development after oocyte transfer in the mare. (Abstract). Theriogenology 47:392 (1997). Alm H and Hinrichs K. Effect of cycloheximide on nuclear maturation of horse oocytes. (Abstract). Archiv fur Tierzucht., Dummerstorf (Special Issue) 39:77 (1996). Williams KA and Hinrichs K. Morphology and meiotic competence of oocytes in relation to follicle atresia in the mare. (Abstract). Proceedings, 12th Int. Cong. Anim. Reprod. 3:17-4 (1996). Overstrom EW, Duby RT, Dobrinsky J, Hinrichs K, Roche JF, and Boland MP. Sodium transport properties of the bovine and equine blastocyst. (Abstract) in: Bavister B, ed., Preimplantation Embryonic Development, Springer-Verlag, New York, p. 323 (1993). Hinrichs K and Schmidt AL. Reversible meiotic arrest of horse oocytes by coculture with follicular components. (Abstract) Theriogenology 39:232 (1993). Hinrichs K, Friedman PP, Martin MG. Evaluation of in vitro maturation of horse oocytes using fluorescence microscopy. (Brief communication) Proceedings, 12th Int. Cong. Anim. Reprod. 1:330-332 (1992). Hinrichs K, Martin MG and Friedman PP. Effect of follicular components on maintenance of meiotic arrest in horse oocytes. (Abstract) Theriogenology 37:223 (1992). Hinrichs K. The role of endometrial swabs in the diagnosis (and pathogenesis?) of endometritis. (Editorial) Cornell Vet. 81:233-237 (1991). Reprinted in the New Zealand Veterinary Association Equine Branch Newsletter March 1992, pp. 31-34. Hinrichs K. A simple technique that may improve the rate of embryo recovery on uterine flushing in mares. (Work-in-progress report) Theriogenology 33:937-942 (1990). Hinrichs K, Cummings MR, Sertich PL and Kenney RM. Bacteria recovered from the reproductive tracts of normal mares. (Brief communication) Proceedings, Am. Assoc. Equine Pract., pp. 11-16 (1989). Hinrichs K, Klunder LR and Riera FL. Embryo transfer in mares with gonadal dysgenesis. (Abstract) Theriogenology 31:204 (1989). Sertich PL, Hinrichs K, Schiereck DE and Kenney RM. Periparturient events in ovariectomized embryo transfer recipient mares. (Brief communication) Proceedings, 11th Int. Cong. Anim. Reprod. Artificial Insemination, p. 193. (1988). Hinrichs K. Establishment of pregnancy after embryo transfer in ovariectomized mares: Effect of length of progesterone treatment on pregnancy rate and pattern of uterine proteins. Ph.D. Dissertation, University of Pennsylvania. (1988). Hinrichs K and Kenney RM. A colpotomy procedure to increase oocyte recovery rates on aspiration of equine preovulatory follicles. (Abstract) Theriogenology 27:237 (1987). Hinrichs K, Sertich PL, Cummings MR, and Kenney RM. Pregnancy in ovariectomized mares achieved by embryo transfer. (Brief communication) Equine Vet. J. Suppl. 3:74-75 (1985). Van Huffel XM, Varner DD, Hinrichs K, Garcia MC, Strzemienski PJ and Kenney RM. A comparison of visual and photomicrographic techniques for stallion spermatozoal motility analysis. (Brief communication) Proceedings, Soc. Theriogenology, pp. 162-166 (1983).


Submitted for publication Choi YH, Ross P, Velez IC, Macías-García B, Riera F and Hinrichs K. Cell lineage allocation in equine blastocysts cultured in varying medium glucose concentrations. Lewis N, Hinrichs K, Schnauffer K, Morganti M, Argo C. McG. Constraints and limitations in the development of an equine ICSI programme PRESENTATIONS Presentations marked * are associated with publications previously listed. International 2015 “Health of horses produced by ART: Embryo transfer, oocyte transfer, ICSI and cloning” Equine Reproduction

Symposium, International Embryo Transfer Society, Paris, France, January10. 2014 “Translation of research in equine ICSI to clinical practice” Seminar series, Centre de Recherche en

Reproduction Animal (CRRA), University of Montréal, Saint-Hyacinthe, Quebec, December 10. 2014 “The effect of mare age on efficiency of ICSI / in vitro embryo culture for foal production” Havemeyer

Foundation Workshop on Comparative Aspects of Reproductive Aging in the Mare and Woman, Estes Park, Colorado, October 10.

2014 “Practical considerations in equine assisted reproduction” Workshop on Advanced Equine Reproduction,

Faculties of Agronomy and Veterinary Science, University of Buenos Aires, Argentina, May 31 2014 “Equine intracytoplasmic sperm injection (ICSI)” 2o International Congress of the Sociedad Argentina de

Tecnologías Embrionarias (Argentine Society of Embryo Technologies), Buenos Aires, Argentina, May 30. 2014 “Assisted reproductive techniques in the horse” and laboratory on oocyte collection, Master’s Program in

Equine Reproduction, University of Extremadura, Cáceres, Spain, May 12-13. 2014 “Equine oocyte collection” and “Oocyte transfer and ICSI: Clinical application” ISER Veterinary Conference,

Hamilton, New Zealand, January 31. 2014* “Use of in vitro maturation of oocytes, intracytoplasmic sperm injection and in vitro culture to the blastocyst

stage in a commercial equine assisted reproduction program” XI International Symposium on Equine Reproduction, Hamilton, New Zealand, January 30.

2013 “Embryo transfer, oocyte transfer and fertilization in vitro in the horse” Congress of the Sociedad Argentina de

Tecnologías Embrionarias (Argentine Society of Embryo Technologies), Corrientes, Argentina, April 12. 2013* “Assisted reproductive techniques in the horse” Annual Conference, International Embryo Transfer Society,

Hannover Germany, January 20. 2012 “Sperm protein tyrosine phosphorylation in the stallion” Department of Reproductive Biology, Research

Institute for the Biology of Farm Animals, Dummerstorf, Germany, September 10. 2012* “Hyperactivated sperm motility: Are equine sperm different?” 6th International Symposium on Stallion

Reproduction, Vienna, Austria, September 7. 2012* “Embryo biopsy and blastocyst cryopreservation” 8th International Symposium on Equine Embryo Transfer,

Vancouver, Canada, July 28.


2012 “Oocyte aspiration, transfer and ICSI in the horse” Reproductive Biology Unit seminar, Faculty of Veterinary

Medicine, University of Ghent, Ghent, Belgium, June 20. 2011* “Sporadic success of equine in vitro fertilization amid consistent failure – What happened?” Havemeyer

Foundation Workshop on Equine In Vitro Fertilization, Hilton Head, South Carolina, November 11. 2011 “Modern breeding technologies” Havemeyer Foundation 30th Anniversary Meeting, Saratoga, New York,

August 18. 2011* “Biotechnology in equine reproduction” IX National Congress, Società Italiana di Riproduzione Animale

(Italian Society of Animal Reproduction), Valenzano, Italy, June 24. 2010 "Assisted reproductive techniques – clinics and research" Buenos Aires Province Equine Embryo Transfer

group, Lincoln, Argentina, October 29. 2010* “Use of intracytoplasmic sperm injection and in vitro culture to the blastocyst stage for clinical production of

foals post mortem” 10th International Symposium on Equine Reproduction, Lexington, Kentucky, July 29. 2010* “In vitro production of equine embryos” Annual Meeting of the Asociación Española de Reproducción Animal

(Spanish Association of Animal Reproduction), Cáceres, Spain, June 3. 2009 “Recent research on oocyte recovery, ICSI, and embryo development in the horse” Department of Reproductive

Biology, Research Institute for the Biology of Farm Animals, Dummerstorf, Germany, September 16. 2009* “Equine ICSI: History and current status” 13th Annual Conference of the European Society for Domestic

Animal Reproduction, Ghent, Belgium, September 11. 2008* “Oct-4 expression in in vivo and in vitro-produced equine blastocysts” 7th International Symposium on Equine

Embryo Transfer, Cambridge, United Kingdom, July 9. 2007 “Ultrasonography in mare reproduction” Japanese Equine Veterinary Association Meeting, Shizunai, Japan,

January 11. 2006* “Efficient production of cloned horse pregnancies using roscovitine-treated donor cells” 9th International

Symposium on Equine Reproduction, Kerkrade, The Netherlands, August 10. 2006 “Cloning in the horse” Meeting on Equine Reproduction in the 21st Century (European equine veterinary

practitioners) Kerkrade, The Netherlands, August 5. 2005* “Blastocysts, pregnancies and foals from ICSI and nuclear transfer” 4th Meeting of the International Equine

Gamete Group, Kühlungsborn, Germany, September 20. 2005 "In vitro production of equine embryos by intracytoplasmic sperm injection or nuclear transfer" Department of

Reproductive Biology, Research Institute for the Biology of Farm Animals, Dummerstorf, Germany, January 13.

2005 "Relationships among chromatin configuration, ovary storage and oocyte maturation in vitro" Equine Oocyte

Forum, The Royal Veterinary and Agricultural University , Copenhagen, Denmark, January 7. 2004* “Transfer of in vitro-produced equine embryos” 6th International Equine Embryo Transfer Symposium, Rio de

Janeiro, Brazil, August 5. 2004* “Comparison of embryo culture media for blastocyst development after intracytoplasmic sperm injection of in

vitro-matured equine oocytes” (Poster) International Embryo Transfer Sociey, Portland, Oregon, January 12.


2003* “Interactions between time of oocyte recovery (immediate vs delayed) and duration of in vitro maturation on

developmental competence of horse oocytes” Havemeyer Foundation Workshop: Transporting Gametes and Embryos. Brewster, Massachusetts, October 3.

2002* “Effect of holding time and media on meiotic and developmental competence of horse oocytes” 8th

International Symposium on Equine Reproduction, Fort Collins, Colorado, July 25. 2001* “The relationship between oocyte quality and developmental potential”, Havemeyer Foundation Workshop:

From Epididymis to Embryo, New Orleans, Louisiana, October 20. 2001* “Effects of initial cumulus morphology and addition of cytochalasin B on fusion, activation and cleavage of

horse oocytes undergoing nuclear transfer.” (Poster) Annual Conference, International Embryo Transfer Society. Omaha, Nebraska, January 15.

2000* “Comparison of bovine and equine oocytes as host cytoplasts for equine nuclear transfer” 5th International

Symposium on Equine Embryo Transfer, Saari, Finland, July 7. 1999 “Maturation of horse oocytes” Faculty of Veterinary Medicine, University of Bari, Bari, Italy, June 11. 1998* “Effect of time of follicle aspiration on pregnancy rate after oocyte transfer in the mare ” 7th International

Symposium on Equine Reproduction, Pretoria, South Africa, July 16. 1998* “Embryo production by assisted reproduction in the horse” Annual Conference, International Embryo Transfer

Society. Boston, Massachusetts, January 19. 1997 “Fertilization of equine oocytes in vitro and in vivo” Applied and Technical Day on Equine Embryo Transfer

and Other Advanced Techniques. Reims, France, January 18. 1997* “Cumulus expansion, chromatin configuration and meiotic competence in horse oocytes” 4th International

Symposium on Equine Embryo Transfer and Other Advanced Techniques. Reims, France, January 17. 1997* “Effect of oocyte maturation time on embryo development after oocyte transfer in the mare” (Poster). Annual

Conference, International Embryo Transfer Society, Nice, France, January 15. 1996* “Manipulation of maturation in vitro” Symposium on Oocyte Maturation and Early Embryonic Development

under the Influence of Biologically Active Substances, Dummerstorf-Rostock, Germany, September 23. 1996* “Morphology and meiotic competence of oocytes in relation to follicle atresia in the mare” (Poster) 13th International Congress on Animal Reproduction, Sydney, Australia, July 3. 1994* “Use of ovariectomized mares as embryo transfer recipients” and “Future technology: oocyte transfer,

maturation and in vitro fertilization” I Congresso de Medicina Equina, Sao Paulo, Brazil, August 17. 1994* “Activation of horse oocytes;” 6th International Symposium on Equine Reproduction, Caxambu, Brazil,

August 9. 1993* “Reversible meiotic arrest of horse oocytes by coculture with follicular components” (Poster) Annual

Conference, International Embryo Transfer Society, Baton Rouge, Louisiana, January 11. 1992* “Chromatin configurations of germinal vesicle stage and maturing horse oocytes” 3rd International Symposium

on Equine Embryo Transfer, Buenos Aires, Argentina, November 17. 1992* “Effect of cumulus morphology on maturation of horse oocytes in vitro” International Scientific Conference on

Biotechnics in Horse Reproduction, Krakow, Poland, August 31.


1992* “Evaluation of in vitro maturation of horse oocytes using fluorescence microscopy” (Poster) 12th International

Congress on Animal Reproduction, The Hague, The Netherlands, August 25. 1992 “Endometritis in progesterone-treated mares given uterine inocula of Pseudomonas aeruginosa” John Hughes

International Workshop on Equine Endometritis, Newmarket, England, August 20. 1992* “Effect of follicular components on maintenance of meiotic arrest in horse oocytes” (Poster) Annual

Conference, International Embryo Transfer Society, Denver, Colorado, January 13. 1991 “In vivo maturation and retrieval of equine oocytes” Symposium on In Vitro Fertilization and Early Embryonic

Development, AFRC Institute of Animal Physiology and Genetic Research, Babraham, Cambridge, England, January 16.

1990* “Embryonic development after intrafollicular transfer of horse oocytes” 5th International Symposium on Equine

Reproduction, Deauville, France, July 3. 1989* “Differences in protein content of uterine fluid between synchronous and asynchronous ovariectomized

recipient mares” 2nd International Symposium on Equine Embryo Transfer, Banff, Canada, February 3. 1989* “Embryo transfer in mares with gonadal dysgenesis” (Poster) Annual Conference, International Embryo

Transfer Society, San Diego, California, January 16. 1987* “A colpotomy procedure to increase oocyte recovery rates on aspiration of equine pre-ovulatory oocytes”

(Poster) Annual Conference, International Embryo Transfer Society, Dublin, Ireland, January 26. 1987 “Embryo transfer in ovariectomized mares” and “Diagnosis and repair of the lacerated cervix in the mare”

Faculty of the School of Veterinary Medicine, University of Gent, Belgium, January 22. 1986* “Embryo survival after transfer in ovariectomized, progesterone treated mares” 4th International Symposium on

Equine Reproduction, Calgary, Canada, August 28. 1984* “Pregnancy in ovariectomized mares achieved by embryo transfer” 1st International Symposium on Equine

Embryo Transfer, Cornell University, Ithaca, New York, October 9. 1984 “Current research in reproduction at New Bolton Center” Institut National de Recherche Agronomique,

Nouzilly, France, May 30. 1983 “Fertility evaluation of the stallion” Equine Research Station, Newmarket, England, October 20. National 2011* “Biopsy and Vitrification of Expanded Equine Blastocysts” Annual Conference, Society for Theriogenology,

Milwaukee, Wisconsin, August 12. 2010* “Application of Assisted Reproductive Technologies (ART) to Clinical Practice” In-Depth Session, Annual

Convention, American Association of Equine Practitioners, Baltimore, Maryland, December 7. 2009 “Cloning, ICSI and assisted reproduction” Robert M. Kenney Symposium, New Bolton Center, University of

Pennsylvania, Kennett Square, Pennsylvania, September 25. 2009 “Overview of Equine Cloning” Annual Convention, American Quarter Horse Association, San Antonio, Texas,

March 6.


2008 “Equine Cloning: Methods, History and Results” American Quarter Horse Association Stud Book Committee,

Amarillo, Texas, October 15. 2007 “Equine cloning – methods and results” Annual Meeting National Cutting Horse Association, Lexington,

Kentucky, June 23. 2007 “Equine fertilization: ICSI and oocyte transfer” and “Equine cloning” National Convention of the Dutch

Warmblood Breeders' Organization of North America, Austin, Texas, March 2. 2006* “A review of cloning in the horse” 52nd Annual Convention of the American Association of Equine

Practitioners, San Antonio, Texas, December 5. 2006 “Cloning in the horse” Annual Meeting, National Pedigreed Livestock Council, College Station, Texas, May 9. 2005* “An update on equine ICSI and cloning” Annual Meeting, Society for Theriogenology, Charleston, South

Carolina, August 12. 2005 “Cloning: basic concepts and current state of the art” Student American Veterinary Medical Association

Symposium, College Station, TX, March 12. 2004 “Assisted reproduction techniques” Annual Meeting, American Hanoverian Society, Houston, Texas, January

17. 2003 “Oocyte handling techniques” (Workshop) Annual Meeting, American Association of Equine Practitioners,

Baton Rouge, Louisiana, November 20. 2003 “Intracytoplasmic sperm injection as a treatment strategy for subfertile stallions.” First Annual Focus Meeting,

American Association of Equine Practitioners, Fort Collins, CO, July 29. 2002* “Current status and clinical potential of IVF, ICSI and cloning in horses” Annual Meeting, Society for

Theriogenology, Colorado Springs, Colorado, August 10. 2000* “Production of equine embryos by nuclear transfer: comparison of efficiency of equine and bovine cytoplasts”

Annual Meeting, Society for Theriogenology, San Antonio, Texas, November 30. 1999* “Use of non-ovulating, hormone-treated mares as oocyte transfer recipients” Annual Meeting, Society for

Theriogenology, Nashville, Tennessee, September 24. 1997* “Oocyte transfer as a clinical procedure in the mare” 43rd Annual Convention of the American Association of

Equine Practitioners, Phoenix, Arizona, December 9. 1997* “Oocyte collection and maturation” Annual Meeting, Society for Theriogenology, Montreal, Canada,

September 18. 1994* “Assisted reproductive technology in the horse” Annual Meeting, Society for Theriogenology, Kansas City,

Missouri, August 27. 1992* “Potential for gamete manipulation in the horse: GIFT, IVF and embryo transfer” Annual Meeting, Society for

Theriogenology, San Antonio, Texas, August 15. 1992* “Ultrasonographic techniques in mare reproduction” American College of Theriogenologists Equine

Theriogenology Short Course, San Antonio, Texas, August 11, 12.


1991* “Prospects for oocyte aspiration, fertilization and transfer in the mare” 37th Annual Convention of the American Association of Equine Practitioners, San Francisco, California, December 1.

1990* “Ultrasonographic assessment of ovarian abnormalities” 36th Annual Convention of the American Association

of Equine Practitioners, Lexington, Kentucky, December 3. 1990 Panel Presentation, “Semen transport” Harness Expo 90 (United States Trotting Association), Meadowlands

Raceway, East Rutherford, New Jersey, August 3. 1989* “Bacteria recovered from the reproductive tracts of normal mares” 35th Annual Convention of the American

Association of Equine Practitioners, Boston, Massachusetts, December 3. 1986* “Use of ovariectomized, progestogen treated mares as embryo transfer recipients” Annual Meeting of the

Society for Theriogenology, Rochester, New York, September 19. Regional and Local 2014 “Opportunities in Equine Assisted Reproduction” TAMU Horsemen’s Association, Texas A&M University,

College Station, Texas, October 28. 2013 “The TAMU Clinical ICSI Program: Rationale, Procedures, Success Rates and Costs,” and “Emergency

Preservation of Equine Oocytes and Embryos” Equine Reproduction Symposium for Veterinarians, Texas A&M University, College Station, Texas, November 23.

2013 “Clinical use of intracytoplasmic sperm injection (ICSI) in the horse” Legends Equine Reproduction Short

Course, Texas A&M University, College Station, Texas, October 12. 2013 “Clinical application of assisted reproduction in the Horse” Reproductive Biology Forum, Interdisciplinary

Faculty of Reproductive Biology, Texas A&M University, College Station, Texas, October 4. 2013 “Assisted reproductive techniques in the horse” Theriogenology Club, University of California, Davis,

California, February 6. 2012 “In vitro production of equine embryos” The Ed Squires Lecture, Colorado State University, Fort Collins,

Colorado, October 22. 2012 “Use of ICSI in clinical equine reproduction” Intern and Resident Seminar Series, New Bolton Center,

University of Pennsylvania School of Veterinary Medicine, Kennett Square, Pennsylvania, October 16. 2011 “Intracytoplasmic sperm injection: Technique and clinical applications” 2nd Annual Legends Equine

Reproduction Short Course, College Station, Texas, August 27. 2010 “Translation of research to clinical practice in equine assisted reproduction” Annual Retreat, TAMU

Interdisciplinary Faculty of Reproductive Biology, Bryan, Texas, September 24. 2010 “Assisted reproductive techniques and mare research update” Legends Equine Reproduction Short Course,

Texas A&M University, College Station, Texas, August 21. 2010 “Biopsy of embryos for preimplantation genetic diagnosis, and subsequent cryopreservation” Tufts University

School of Veterinary Medicine, North Grafton, Massachusetts, July 6. 2010 “Horse cloning: state of the art” Evening Equine Educational Seminar, Brazos County Extension Horse

Committee, Bryan, Texas, March 23.


2009 “Oocyte collection, oocyte transfer, intracytoplasmic sperm injection (ICSI) and cryopreservation of embryos” Annual Equine Reproductive Symposium for Veterinarians, Texas A&M University , College Station, Texas, October 17.

2009 “Recent advances in equine assisted reproduction” Tufts University School of Veterinary Medicine, North

Grafton, Massachusetts, June 30. 2007 “Overview of assisted reproduction techniques” Annual Equine Reproduction Symposium for Veterinarians,

Texas A&M University, College Station, Texas, November 10. 2007 “In vitro production of foals: cloning and intracytoplasmic sperm injection” Center for Animal Transgenesis

and Germ Cell Research, New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania, September 25.

2007 “Equine cloning update” Tufts University School of Veterinary Medicine, North Grafton, Massachusetts, July

5. 2006 “Overview of assisted reproduction techniques” Annual Equine Reproduction Symposium for Veterinarians,

Texas A&M University, College Station, Texas, November 18. 2006 “Cloning in the horse” Texas Breeders Forum, Tioga, Texas, January 21. 2005 “Update on assisted reproduction” Annual Equine Reproduction Symposium for Veterinarians, Texas A&M

University, College Station, Texas, December 10. 2005 “Nuclear transfer in the horse” Reproduction Forum, Cornell University, Ithaca, New York, October 19. 2005 “Cloning: Techniques and applications” Tufts University School of Veterinary Medicine, North Grafton,

Massachusetts, July 8. 2004 “Overview of assisted reproductive techniques” and oocyte collection and handling laboratory, Annual Equine

Reproduction Symposium for Veterinarians, Texas A&M University, College Station, Texas, December 11,12. 2003 “Update on assisted reproduction and cloning;” and embryo transfer wet laboratory, Annual Equine

Reproduction Symposium for Veterinarians, Texas A&M University, College Station, Texas, December 13, 14. 2002 “Overview of assisted reproductive techniques;” and embryo transfer wet laboratory, Annual Equine

Reproduction Symposium for Veterinarians, Texas A&M University, College Station, Texas, December 14, 15. 2002 “Practical aspects of assisted reproduction in the horse” Brazos Valley Veterinary Medical Association,

College Station, Texas, February 5. 2001 “Emerging assisted reproduction techniques” and “Overview of oocyte transfer;” Embryo transfer wet

laboratory, Annual Equine Reproduction Symposium for Veterinarians, Texas A&M University, College Station, Texas, December 8, 9.

2001 “Breeding management with cooled-transported and frozen semen” Brazos Association for Classical

Horsemanship, College Station, TX, April 26. 2000 “Emerging assisted reproduction techniques” and “Overview of oocyte transfer;” Embryo transfer wet

laboratory, Annual Equine Reproduction Symposium for Veterinarians, Texas A&M University, College Station, Texas, December 9, 10.

2000 “Equine Reproductive Biology -- Link Equine Research Endowment Fund Update” Texas Equine Industry

Conference, College Station, Texas, October 20.


2000 “Puzzles in maturation of horse oocytes” Reproductive Biology Seminar Series, Louisiana State University,

Baton Rouge, Louisiana, September 28. 2000 “Assisted reproduction in the horse” Brazos Association for Classical Horsemanship, College Station, TX,

February 17. 1999 “Emerging assisted reproduction techniques” and “Overview of oocyte transfer;” Embryo transfer wet

laboratory, Annual Equine Reproduction Symposium for Veterinarians, Texas A&M University, College Station, Texas, December 11,12.

1999 “Advances in technologies for equine reproduction” and “New reproductive technologies” Texas Equine

Industry Conference, College Station, Texas, November 5, 6. 1999 “Oocyte maturation” Annual Reproductive Physiology Symposium, Texas A&M University, College Station,

Texas, January 12. 1998 “New assisted-reproduction techniques in the horse: embryo transfer, oocyte transfer and IVF” Annual

Meeting, North East Morgan Horse Association, Worcester, Massachusetts, February 7. 1997 “The estrus cycle and breeding management” Equine Health Seminars, SRH Veterinary Services, Hamilton,

Massachusetts, February 13. 1996 “The estrus cycle: Normal and abnormal” Sixteenth Annual Canine Symposium, Tufts University School of

Veterinary Medicine, North Grafton, Massachusetts, March 2. 1996 “Maturation of horse oocytes” Animal and Veterinary Science Seminar Series, University of Massachusetts,

Amherst, Massachusetts, February 14. 1995 “What to expect when your mare is expecting” Equine Health Seminar Series, Tufts University School of

Veterinary Medicine, North Grafton, Massachusetts, November 14. 1995 “Breeding soundness examination in the mare” and “Handling of transported semen” Annual Meeting,

Massachusetts Veterinary Medical Association, February 3. 1993 “Breeding your mare” Equine Health Seminar Series, Tufts University School of Veterinary Medicine, North

Grafton, Massachusetts, March 3. 1992 “Maturation and suppression of maturation of horse oocytes” Reproductive Physiology Seminar Series,

Cornell University, Ithaca, New York, December 2. 1992 “Assisted Reproductive Technology in the Horse” Animal and Veterinary Science Seminar Series, University

of Massachusetts, Amherst, Massachusetts, May 20. 1992 “Research update: Equine embryo transfer” Large Animal Practitioners Conference, Tufts University School of

Veterinary Medicine, North Grafton, Massachusetts, January 4. 1991 “Reproductive Strategies in Mammals” Boston Museum of Science, Boston, Massachusetts, November 10. 1991 “The mare during estrus and early pregnancy,” and “Physiology of pregnancy; twinning” 8th Annual Equine

Symposium, Tufts School of Veterinary Medicine, North Grafton, Massachusetts, February 2. 1990 “Embryo transfer” and “Artificial insemination” Massachusetts Bay Colony Horseman's Association, Taunton,

Massachusetts, November 10.


1990 “Breeding management of the mare” Tufts University Veterinary Technician Program, Westboro,

Massachusetts, April 22. 1990 “Birth” 7th Annual Equine Symposium, Tufts University School of Veterinary Medicine, North Grafton,

Massachusetts, January 20. 1989 “Differential diagnosis in cases of enlarged ovary in the mare” Massachusetts Veterinary Medical Association

Continuing Education Seminar, Taunton, Massachusetts, June 7. 1989 “Update on endometritis”, “Hormonal therapy”, and “Parturition and its problems” Equine Reproduction and

Perinatology Symposium, Tufts University School of Veterinary Medicine, North Grafton, Massachusetts, March 1.

1989 “The foaling mare” 3rd Annual Equine Reproduction Seminar, Hampton Veterinary Services, East Hampton,

Massachusetts, January 24. 1988 “Parturition in the mare” and “Hormonal therapy in the mare” Lehigh Valley Veterinary Medical Association

Continuing Education Meeting, Allentown, Pennsylvania, February 10. 1987 “Uterine proteins in synchronous and asynchronous ovariectomized embryo recipient mares” Reproductive

Biology Group, University of Florida, Gainesville, Florida, October 28. 1986 “Reproductive physiology and seasonality” and “Pregnancy, parturition, and care of the neonate,” Equine

Reproduction Short Course for Producers, New Bolton Center, Kennett Square, Pennsylvania, February 1. 1986 “Review of estrous cycle and seasonality” and “Hormonal therapy in the mare” Equine Reproduction Short

Course, Penn Annual Conference, Philadelphia, Pennsylvania, January 30. 1985 “Breeding soundness examination in the mare” Penn Annual Conference, Philadelphia, Pennsylvania, January

30. 1983 “Artificial insemination and an introduction to embryo transfer” Pennsylvania State University Extension

Horse Breeding Management Short Course, King of Prussia, Pennsylvania, February 25.

KATRIN HINRICHS EDUCATION Ph.D. · KATRIN HINRICHS CURRICULUM VITAE, page 5 Carrie Hanna, MS...

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