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Transcript of jurnal OSCC
7/23/2019 jurnal OSCC
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Aldy Novrizal
0906554390 Liviu Feller, Johan Lemmer
Journal of Cancer Therapy, 2012, 3, 263-268
Oral Squamous Cell Carcinoma:Epidemiology, Clinical Presentation
and Treatment
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Oral cancer is the sith most common cancer !orld!ide"ore than #$% o& all oral cancers are'is( &actors &or oral SCC
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Habits Of
Chewing Tobao
)n the
)ndiansu*continent
The highestincidence andprevalence o&
oral SCC
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The ai! of this artile
to revie! the epidemiology, clinical
&eatures, and prognosis o& oralSCC+
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Oral "CC fre#$ently a%et
Epidemiology o& Oral SCC
&o!en
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O'A( "CC )N &*"T*'NCO+NT')*"
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ventral s$rfae of the tong$e and the ,oor of the !o$thventral s$rfae of the tong$e and the ,oor of the !o$thlined by thin non-Carinogens an a$!$lateOral "CC
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.ri!ary t$!o$r iss!all and no
evidene of regional
ly!.hnodeinvolve!ent or
distant !etastasis
/'ONO")" )" 1*"T
Clinical Features and Course o&Oral SCC
TN2 stage T-t$!o$r size N-
nodal!etastasis 2-
distant!etastasis ofthe .ri!ary
t$!o$rorrelates well
with thes$rvival rate
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already of s$bstantial size and linially detetable"CC of the li. hard .alate and !aillary"CC of the tong$e of the ,oor of the !o$th and of t
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/revalene
Ethnicity and SocioEconomicStatus as They 'elate to Oral SCC
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red$e the inidene of the diseaseis to detet the disease in its initial stagesto .ro!.tly instit$te e%etive and e7ient treat!ent
Prevention and Control o& OralSCC
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reduce the incidence o& oral SCC *y almost-$%
abstinene fro! the$se of tobao betel
#$id and ons$!.tionof aloholi beverages
together with an
inrease in fresh fr$itsand vegetables in thediet
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As a /ratitioner8
routinely per&orm
oral so&t tissueeaminations !hoare (no!n to practice
ha*its associated!ith increased ris( o&
oral cancer
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The treat!ent of oral "CC
: eision;resetion
<: radio-thera.y
3: syste!i ytotoi he!othera.y
4: blo=ing of e.ithelial growth fator ree.tor*>-'
5: or a o!bination of these
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eradiate the aner
/ri!ar y Ai! of the treat!ent
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The use of tobacco and betel quid, heavydrinking of alcoholic beverages and a diet lowin fresh fruits and vegetables are the majorrisk factors for oral SCC.
The 5-year survival rate is oor at about 5!",mainly because about two-thirds of ersonswith oral SCC already have large lesions at thetime of diagnosis.
Summary