1. Yassin M. ALSaleh

2. : ( ) 3. Introduction Adequate dietary intake of calcium (Ca2+) and vitamin D (VitD) in children is important to guarantee normal bone mineralization . Ca2+ is also important in coagulation cascade, in neuromuscular excitability and contraction, in enzyme hormones and growth factors activity, in secretion of hormones and in cell growth and differentiation 4. Introduction Dietary Recommended Intake (DRI) for Ca2+: 700 mg/day for children aged 13 years. 1000 mg/day for children aged 48 years. 1300 mg/day for children aged 910 year and adolescents. 5. Introduction has a roles in both innate and adaptive immunity. Also implicated in the prevention of a number of conditions including autoimmunity, atopic disorders, certain forms of cancer, chronic hepatitis C, obesity and cardiovascular diseases 6. Introduction American Academy of Pediatrics (AAP) recommended daily intake is 400 IU of vit D for infants, children and adolescents . Unfortunately, despite this recommandation, studies have reported a high rate of VitD insufficiency in the pediatric age Rationale is a multi-factorial. one of the reasons is the insufficient intake related to dietary habits. 7. We investigated Ca2 + and VitD intake. the efficacy and applicability of a nutritional intervention to aimed optimize Ca2+ and VitD intake in a population of healthy children. Objectives: 8. METHODS The study protocol was approved by the Ethics Committee of the Medical School of the University of Naples"Federico II.in Italy a randomized controlled trial. From December 2008 to February 2009, 9. Inclusion criteria healthy subjects (male and female, age range 317 years) consecutively observed as outpatients at Department for routine clinical examination because vaccination program. 10. exclusion criteria Malnutrition (defined as a weight/height ratio