J. N. Alpert M. S. Badr J. D. Bisognano R. Connell ... · Normal Sleep.- Pharmacology of Sleep.-...

springer.com/NEWSonline 89News 8/2011 Medicine & Public Health

J. N. Alpert, University of Texas Medical School, Houston, TX, USA

The Neurologic DiagnosisA Practical Bedside Approach

The Neurologic Diagnosis: A Practical Bedside Approach is an introductory text that simplifies the often unwieldy method of making a neurologic diagnosis. Medical students are often intimi-dated by a deluge of data, extensive differential diagnoses, and have no organizational structure to follow. Diagnostic techniques of general medi-cine are not applicable. Neurology is a unique specialty since it requires the intermediary step of an anatomic diagnosis prior to proffering a differential diagnosis. Yet the required knowledge of neuroanatomy need not be profound for the student who will specialize in any field other than neurology and neurosurgery.

Features 7 Focused, introductory text that simplifies the method of making a neurologic diagnosis 7 Concisely written for medical students and resi-dents 7 Emphasizes novel, practical approaches and techniques that can be used to establish neuro-anatomic diagnosis before formulating a differntial diagnosis

Contents Forward.- Preface.- Introduction.- The Ten Neuroanatomic Diagnoses.- The Neurologic History Holds the Diagnostic Keys.- Neurologic Examination.- Evaluation of the Poorly Respon-sive Patient.- The Six Major Anatomic Decussa-tions with Clinical Correlation.- Cerebrovascular Anatomy with Clinical Correlation.- Autonomic Nervous System Anatomy with Clinical Correla-tion.- Neuromuscular Diseases: Neuroanatomic and Differential Diagnoses.- Common Symptoms in the Neurology Clinic.- Diagnostic Dilemmas.- Neurologic Terminology.- Index to Diseases.

Field of interestNeurology

Target groupsProfessional/practitioner

Type of publicationMonograph

M. S. Badr, Wayne State University, Detroit, MI, USA (Ed.)

Essentials of Sleep MedicineAn Approach for Clinical Pulmonology

Features 7 Offers a clear approach to the different sleep disorders, with a major focus on respiratory disor-ders of sleep 7 Provides a concise, evidence-based review of sleep medicine for the pulmonolo-gist and other health professionals 7 Includes differential diagnosis strategies for common sleep complaints and an evidence-based approach to diagnosis and management 7 Includes a review of the current standards of practice, emerging technology and unresolved issues awaiting further research 7 Developed by an international group of renowned authors

Contents Normal Sleep.- Pharmacology of Sleep.- Obstruc-tive Sleep Apnea: Diagnosis with Polysomnog-raphy and Portable Monitors.- Approach to Hyper-somnia.- Obstructive Sleep Apnea: Epidemiology of Sleep Apnea.- Obstructive Sleep Apnea: Clinical features and adverse consequences.- Assess-ments of Driving Risk in Sleep Apnea.- Nasal Continuous Positive Airway Pressure (CPAP) Treatment.- Obstructive Sleep Apnea: Oral Appli-ances.- Obstructive Sleep Apnea: Surgery.- Sleep and Lung Disease.- Central Sleep Apnea.- Insomnia: Etiology, Clinical Manifestations, and Morbidity.- Management of Insomnia for the Pulmonologist.- Circadian Disorders for the Pulmonologist.- Narcolepsy and Idiopathic Hyper-somnia.- Parasomnias.- Movement Disorders for the Pulmonologist.- Perioperative Care of Patients with Obstructive Sleep Apnea Syndrome.- Sleep and Critical Illness.

Fields of interestPneumology/Respiratory System; Internal Medi-cine; Primary Care Medicine


Type of publicationContributed volume

J. D. Bisognano, R. Beck, R. Connell, University of Rochester Medical Center, Rochester, NY, USA (Eds.)

Manual of Outpatient Cardiology

Practical, didactic format designed to deliver point-of-care information to practitioners of cardiology. Highly illustrated with schematics and useful clinical figures, this will be an essential reference to all outpatient cardiology procedures.

Features 7 A succinct and up to date review of diagnosis and management guidelines 7 Accessible to providers of various levels - medical students, nurses, mid-level providers, residents, fellows, primary care physicians and various subspecialists 7 A comprehensive review for non cardiologists, but also a reference guide for trainees

Contents Section I – Cardiac Diagnostics.- 1. HP.- 2. Evalu-ation of Heart Rhythms.- 3. Cardiac Imaging.- 4. Cardiac Stress testing.- 5. Coronary Evaluation-Cardiac catheterization, CT Angio.- Section II – Common Cardiac Diseases.- 6. Hypertension.- 7. Dyslipidemia.- 8. Coronary artery disease.- 9. Valvular Disease.- 10. Arrhythmias.- 11. Conges-tive Heart Failure.- 12. Vascular Disease – Periph-eral/Aorta.- Section III – Approach to the Patient.- 13. Chest pain.- 14. Syncope/Dizziness.- 15. Palpitations.- 16. New Murmur .- 17. Dyspnea/SOB.- 18. Pre-op evaluation.- 19. Activity Limita-tions.

Fields of interestMedicine/Public Health, general


Type of publicationManual

Due November 2011

2012. CCXLVI, 365 p. 45 illus., 34 in color. Softcover

7 € 39,95 | £35.997 * € (D) 42,75 | € (A) 43,95 | sFr 57,50ISBN 978-1-4419-6723-7

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Due November 2011

2012. XII, 493 p. 29 illus., 12 in color. (Respiratory Medi-cine) Hardcover

7 € 179,95 | £162.007 * € (D) 192,55 | € (A) 197,94 | sFr 258,00ISBN 978-1-60761-734-1

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Due October 2011

2012. VI, 475 p. 107 illus., 59 in color. Softcover

7 approx. € 35,99 | £32.997 approx. * € (D) 38,51 | € (A) 39,59 | sFr 52,00ISBN 978-0-85729-943-7

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www.springer.com/978-1-4419-6723-7



springer.com/NEWSonline90 News 8/2011Medicine & Public Health

M. F. Collen, Kaiser Permanente, Oakland, CA, USA

Computer Medical DatabasesThe First Six Decades (1950–2010)

Chapter 1 offers an overview of the basic computer technology. Each succeeding chapter, describes the problems in medicine, followed by a review in chronological sequence of why and how computers were applied to try to meet these problems. Only the technical aspects of computer hardware, soft-ware, and communications are discussed as they are necessary to explain how the technology was applied. This approach generally led to defining the objectives for applications of medical informatics. At the end of each chapter, the author summa-rizes his personal views and interpretations of the chapter contents. Although the concurrent evolu-tion of medical informatics in Canada, Europe, and Japan certainly influenced workers in the United States, the scope of this historical review is limited to the development of medical informatics within the United States.

Features 7 At the end of each chapter, the author summa-rizes his personal views and interpretations of the chapter contents 7 Review focused on medical informatics within the United States 7 Written by an expert in the field of health informatics

Contents Chapter 1 Prologue: The Evolution of Computer Databases.- Chapter 2 The Development of Medical Databases.- Chapter 3 Processing Text in Medical Databases.- Chapter 4 Primary Medical Record Databases.- Chapter 5 Specialized Medical Databases.- Chapter 6 Secondary Medical Research Databases.- Chapter 7 Bio-Surveillance Claims Databases.- Chapter 8 Medical Knowledge Databases.- Chapter 9 Medical Bibliographic Data-bases.- Chapter 10 Epilogue.

Fields of interestHealth Informatics


Type of publicationProfessional book

F. S. De Ponte, University of Messina, Italy (Ed.)

Bisphosphonates and Osteonecrosis of the Jaw: A Multidisciplinary Approach

During the early 19th century, it was discovered that adding yellow (now called white) phospho-rous to matchstick heads made it easier to ignite matches. The phosphorous vapors were breathed in by workers and combined with other chemicals in the body to produce a potent nitrogen-containing bisphosphonate. Today’s oral nitrogen-containing bisphosphonates and intravenous nitrogen-containing bisphosphonates circulate around the body the same way as the phosphorous vapors, and are absorbed into bone and ingested by osteoclasts.

Features 7 First multidisciplinary text on the subject, by worldwide experts 7 Update of the latest advances, technical details, and expert advice regarding this subject 7 Presents multiple designs, explanatory figures on physiopathogen-esis, and clinical imaging 7 Clinical case discus-sions and practical advice for incorporation into common practice

Contents Preface-1. Introduction - 2. Pharmacology: Mecha-nism of Action of Bisphosphonates- 3. Use of Bisphosphonates in Oncology, Hematology and Osteoporosis - 4. Biomorphology in BIONJ: Anatomy and History - 5. Ethiopathogenesis and clinic of BIONJ - 6. Instrumental Diagnosis.- 7. Microbiological Aspects - 8. Prevention and role of Dentist - 9. Conservative Treatment: Oxygen, Ozone and Laser - 10. Minimally Invasive Surgical Treatment - 11. Major Surgery in BIONJ - 12. The future of BIONJ

Fields of interestOral and Maxillofacial Surgery; Dentistry; Hema-tology



A. Ebringer, King’s College, London, UK

Rheumatoid Arthritis and Proteus

Contents Scope and Distribution of the RA Problem.- History of the Attempts to Find the Cause of RA.- HLA-DR1/4 and Antibodies to Proteus in London.- Antibodies to Proteus in Irish patients with rheumatoid arthritis.- Antibodies to Proteus in rheumatoid arthritis patients from Bermuda and from Hertfordshire in England.- Antibodies to Proteus in rheumatoid arthritis patients from Brest and Toulouse in France.- Dutch patients with rheumatoid arthritis have antibodies to Proteus.- Anti-Proteus antibodies in Norwegian rheumatoid arthritis patients following a lactovegetarian diet.- Antibodies to Proteus in rheumatoid arthritis patients from Norway, Spain and England.- Anti-bodies to Proteus in rheumatoid arthritis patients from southern Japan.- Urine Cultures and Correla-tion.- Molecular similarity between the “shared epitope” of rheumatoid arthritis and bacteria.- The “shared epitope”, Proteus haemolysin, XI collagen and rheumatoid arthritis.- Gram-negative bacteria possess sequences which resemble the “shared epitope”but only Proteus infect rheumatoid arthritis patients.- Immune responses to Proteus in rheumatoid arthritis patients from Finland and Japan.- Molecular similarity between the rheu-matoid arthritis associated motif EQKRAA and structurally related sequences of Proteus.- Rheu-matoid arthritis sera are cytotoxic to cells bearing HLA and collagen susceptibility sequences.- The scientific method of Sir Karl Popper. Rheumatoid arthritis and “Popper sequences”.

Field of interestRheumatology



Due September 2011

2012. XII, 292 p. Hardcover


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Due September 2011

2011. VIII, 185 p. 98 illus., 76 in color. Hardcover

7 € 99,95 | £90.007 * € (D) 106,95 | € (A) 109,95 | sFr 143,50ISBN 978-88-470-2082-5

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Due October 2011

2011. VIII, 242 p. 53 illus., 2 in color. Softcover

7 € 99,95 | £90.007 * € (D) 106,95 | € (A) 109,95 | sFr 143,50ISBN 978-0-85729-949-9

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M. Espié, Hôpital Saint-Louis, Paris, France

Diagnostic et décision dans le cancer du sein précoce

Grâce au dépistage précoce, la taille des cancers du sein est en diminution ce qui permet davan-tage de traitements conservateurs et moins de traitements complémentaires à l’acte loco-régional. Mais les progrès de l’imagerie amènent de nouvelles questions : quels gestes proposés en cas de lésions infra-cliniques, à quoi sert la classifica-tion BIRAD… La prise en charge des patientes se complexifie et les choix thérapeutiques deviennent de plus en plus ardus. Nous tendons à adapter nos traitements au plus près du profil évolutif de la tumeur de chaque patiente : du curage ganglion-naire au ganglion sentinelle, moins de chimio-thérapie, irradiations mammaires partielles….Mais comment être certain que nous ne faisons pas courir davantage de risque de rechute aux pati-entes ? Cet ouvrage reprend les critères de décision validés en 2011 au moment du diagnostic avec la radiologie et aux différentes étapes thérapeutiques sans oublier la dimension psychologique fonda-mentale de la prise en charge de ces patientes.

Features 7 Cet ouvrage reprend les critères de décision validés en 2011 dans le domaine du cancer du sein 7 Il apporte des réponses aux nouvelles questions amenées par les progrès de l’imagerie 7 Contribution des meilleurs experts du domaine du diagnostic et de la décision

Fields of interestMédecine, généralités; Oncologie; Radiologie diagnostic


E. Freye, University of Düsseldorf, Neuss-Uedesheim, Germany

Acquired Mitochondropathy – A New Paradigm in Western Medicine explaining Chronic DiseasesThe Safety Guide for Prevention and Therapy of Chronic Ailments

The book on Acquired Mitochondropathy offers a new perspective on the understanding and the treatment of chronic ailments. Addressing a new paradigm deemed necessary, since in one of every four adults in the western world chronic ailments are on the rise.

Features 7 Proven facts from basic science and clinical studies support the new paradigm for nitric oxide/peroxynitrite on mitochondrial failure 7 Expand the understanding of mitochondrial-related illnesses, caused by the increasingly addition of toxic by-products in the daily food chain 7 Anti-oxidants can be considered key-products in the prevention and treatment of chronic ailments of the Western world

Contents 1. The mitochondrion - essential part in cellular function.- 2. Definition of mitochondropathy - nitrosative stress.- 3. Nitric oxide, a Janus two-faced molecule.- 4. Representative ailments with excess nitric oxide formation.- 5. Principles in nitrosative stress.- 6. Nitrosative stress in diverse multisystem diseases.- 7. Points to consider in therapy of mitochondropathy.

Fields of interestMedicine/Public Health, general; Biomedicine general; Pharmacy

Target groupsResearch


M. Y. Henein, University of Umea, Sweden (Ed.)

Clinical EchocardiographyAssociate editors: M. Sheppard, J. R. Pepper, M. Rigby, Royal Brompton Hospital, London, UK

The main target of clinical and academic cardi-ology activities is to optimize the patient’s manage-ment and ultimately their welfare. Professionals manage patients according to their own under-standing of disease process; clinicians concentrate on alleviating the symptoms and echocardiogra-phers on identifying the disease. This book helps to ‘cross the barrier’ and describes the common ground between physiologic disturbances and their management which should ideally form the shared basis for understanding and managing all cardiac problems.

Features 7 Integrates the investigation of the echocardio-graphic findings with the pathologic, clinical and surgical aspects of heart disease 7 Includes stun-ning color echocardiographic images of various heart diseases with reference to their pathologic appearance and physiology 7 Clinical comments on patient management, which are not included in other echocardiography texts

Contents 1. Mitral valve.- 2. Aortic valve.- 3. Tricuspid valve.- 4. Pulmonary valve.- 5. Valve substitutes.- 6. Endocarditis.- 7. Pulmonary hypertension.- 8. Coronary artery disease.- 9. Dilated cardiomy-opathy.- 10. Hypertrophic cardiomyopathy.- 11. Restrictive cardiomyopathy.- 12. Pericardial disease.- 13. Cardiac tumors.- 14. Disease of the aorta.

Fields of interestCardiology; Imaging / Radiology; Diagnostic Radiology



A paraître novembre 2011

2012. 192 p. (Oncologie pratique) Broché


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Due October 2011

2012. X, 403 p. 158 illus., 117 in color. Hardcover

7 € 149,95 | £135.007 * € (D) 160,45 | € (A) 164,94 | sFr 215,00ISBN 978-94-007-2035-0

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Due December 2011

2nd ed. 2012. XVI, 240 p. 455 illus., 100 in color. With online files/update. Hardcover


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G. Hirschfield, E. J. Heathcoate, University of Toronto Liver Centre, ON, Canada (Eds.)

Autoimmune HepatitisA Guide for Practicing Clinicians

With a focus on practical patient related issues, Autoimmune Hepatitis: A Guide for Practicing Clinicians serves as a useful practical, and much needed, resource for all those physicians presented with managing patients diagnosed with autoim-mune hepatitis, both acutely and over the long term. It provides a basis for clinicians to under-stand the etiology of the disease, as well as special circumstances where management dilemmas often arise. Emphasis is given to providing management advice of immediate use to clinicians, something not presently offered by other larger general texts.

Features 7 Provides management advice of immediate use 7 Focuses on practical patient related issues 7 Written by experts in the field

Contents Introduction.- The Pathogenesis of Autoimmune Hepatitis.- Clinical Presentation.- Confirmation of the Diagnosis: Interpreting the Serology.- Mimics of Autoimmune Hepatitis: Drug-Induced and Immune-Mediated Liver Disease.- When and How to Treat the Adult Patient.- When and How to Treat the Pediatric Patient.- Strategies for Treat-ment Non-Responders: Second Line Therapies and Novel Approaches.- Liver Transplantation for Autoimmune Hepatitis.- Autoimmune Hepa-titis and Pregnancy.- Treatment Side Effects and Associated Autoimmune Diseases.- Managing the Patient with Features of Overlapping Autoimmune Liver Disease.- Autoimmune Hepatitis: A Look Toward the Future.

Fields of interestGastroenterology; Hepatology; Internal Medicine



F. G. Holz, University of Bonn, Germany; D. Pauleikhoff, St. Franziskus-Hospital, Münster, Germany; R. F. Spaide, Vitreous-Retina-Macula Consultants, New York, NY, USA; A. C. Bird, Moorfields Eye Hospital, London, UK (Eds.)

Age-related Macular Degeneration

Age-related macular degeneration is the most common cause for the loss of central vision beyond the age of 50 in industrial nations. Triplication of the number of affected patients is expected over the next 25 years.

Features 7 Updated and enlarged second edition with an authoritative review from an expert panel of clini-cians 7 Strong emphasis on clinical assessment and decision-making 7 Thorough understanding of the disease which is the common cause of blind-ness

Contents Pathophysiology: Epidemiology.- Genetics of AMD.- Aging of the Retina and Retinal Pigment Epithelium.- Complement System.- Current Concepts in AMD-Pathogenesis. Clinical Manifestations: Early AMD.- Neovascular AMD.- Geographic Atrophy. Diagnostics: Fluorescein- und ICG-Angiography.- Optical Coherence Tomography.- Microperimetry. Prophylaxis and Therapy: Nutritional Supplementation.- Laser Photocoagulation and Photodynamic Therapy.- Anti-VEGF-Therapy: Basic Information and Substances.- Anti-VEGF-Therapy: Results and Guidelines.- Combination Therapies for the Treatment of AMD.- Treatment Approaches for Dry Atrophy.- Surgical Therapy. Rehabilitation: Reading Ability.- Magnifying Visual Aids.

Fields of interestOphthalmology; Geriatrics/Gerontology; Diabetes



Y. Illouz, Plastic Surgery, Paris, France; A. Sterodimas, IASO General Hospital, Athens, Greece (Eds.)

Adipose Stem Cells and Regenerative Medicine

Features 7 A readable and informative textbook that tracks the progress made in this fascinating new area of biomedicine 7 Considers all aspects of the subject, with particular attention to adipose cell biology, adipose tissue engineering strategies, and the diverse clinical applications of adipose stem cells 7 Written and edited by leading authorities in the field Wide appeal to researchers, clinicians, and students

Contents ADIPOSE CELL BIOLOGY.- ADIPOSE STEM CELL ENGINEERING.- From Liposuction to Adipose Stem Cell Engineering.- Isolation of Stem Cells from Human Adipose Tissue: Technique, Problems Pearls.- Engineered Scaf-folds and Matrices: Tailored Biomaterials for Adipose Stem Cell Engineering.- Fundamen-tals and Principles of Biomolecules in Adipose Stem Cell Engineering.- Gene Therapy Used for Adipose Stem Cell Engineering Applications.- CLINICAL PERSPECTIVE OF ADIPOSE STEM CELL ENGINEERING IN REGENERATIVE MEDICINE.- The role of Adipose Stem Cell Engineering in Cardiology Diseases.- The role of Adipose Stem Cell Engineering in Endocrino-logical Diseases.- Adipose Stem Cell Engineering: Characterization and Current Application in Neurological Tissue Repair.- FUNDING, INDUS-TRIAL APPROACHES AND REGULATORY MECHANISMS OF ADIPOSE STEM CELL ENGI-NEERING REGENERATIVE MEDICINE

Fields of interestPlastic Surgery; Human Genetics; Medical Biochemistry



Due November 2011

2011 2011. XIV, 244 p. 16 illus., 13 in color. (Clinical Gastroenterology) Hardcover

7 € 139,95 | £126.007 * € (D) 149,75 | € (A) 153,94 | sFr 201,00ISBN 978-1-60761-568-2

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Due December 2011

2nd ed. 2012. X, 278 p. 141 illus., 86 in color. Hardcover

7 € 139,95 | £126.007 * € (D) 149,75 | € (A) 153,94 | sFr 201,00ISBN 978-3-642-22106-4

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Due August 2011


7 € 139,95 | £126.007 * € (D) 149,75 | € (A) 153,94 | sFr 201,00ISBN 978-3-642-20011-3

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D. H. Kirn, Jennerex Biotherapeutics, Inc., San Fran-cisco, CA, USA; T. Liu, Washington University in St. Louis, St. Louis, MO, USA; S. H. Thorne, University of Pittsburgh, Pittsburgh, PA, USA (Eds.)

Oncolytic VirusesMethods and Protocols

Contents Oncolytic Herpes Simplex Virus Engineering and Preparation.- Construction of Capsid-modified Adenoviruses by Recombination in Yeast and Purification by Iodixanol-gradient.- Construc-tion of Targeted and Armed Oncolytic Adeno-viruses.- Syrian Hamster Tumor Model to Study Oncolytic Ad5 Based Vectors.- Adenoviral Gene Expression and Replication in Human Tumor Explant Models.- Imaging Luciferase-expressing Viruses.- In vivo Positron Emission Tomography Imaging using the Sodium Iodide Symporter as a Reporter Gene.- Maintaining and Loading Neural Stem Cells for Delivery of Oncolytic Adenovirus to Brain Tumors.- Targeting Brain Tumor Stem Cells with Oncolytic Adenoviruses.- Propagation, Purifi-cation and In vivo Testing of Oncolytic Vesicular Stomatitis Virus Strains.- Oncolytic Measles Virus Retargeting by Ligand Display.- Exploring Host Factors that Impact Reovirus Replication, Dissemination, and Reovirus-induced Cell Death in Cancer versus Normal Cells in Culture.- Anal-ysis of Three Properties of Newcastle Disease Virus for Fighting Cancer: Tumor Selective Replication, Antitumor Cytotoxicity and Immunostimulation.- Next Generation Oncolytic Vaccinia Vectors.- Evaluation of Innate Immune Signaling Pathways in Transformed Cells.

Fields of interestInfectious Diseases



B. P. Kneubuehl, Universität Bern, Switzerland (Ed.)

Wound BallisticsBasics and Applications

The definitive interdisciplinary reference work for wound ballistics Fundamentals in Physics, arms and ammunition, ballistics Simulating gunshot wounds: Virtopsy – a virtual autopsy method, combining CT, MRT and surface scanning and Materials that reproduce the interaction of soft tissue, bone and blood vessels with a bullet that penetrates the body. Wound ballistics for Short-range and long-range weapons, fragments, such as those from bombs and hand grenades, gas jets from blanks, gas weapons, etc., “Non-lethal” weapons as used by the police, in military opera-tions or in urban settings Specialist knowledge and reference detailed tables: ballistic tables for typical ammunition, ballistic values for numerous types of ammunition, including older types, materials properties, plus additional, hard-to-find data.

Features 7 Interdisciplinary – THE reference work for wound ballistics 7 Fundamentals, specialized knowledge reference work 7 NEW: the latest diagnostic and simulation methods, plus the latest types of rounds 7 The practice and application of wound ballistics in forensic medicine, surgery (esp. emergency and combat surgery) and in interna-tional conventions

Contents Introduction.- Fundamentals.- General wound ballistics.- Wound ballistics for bullets and frag-ments.- Wound ballistics in forensic medicine.- Wound ballistics and surgery.- Wound ballistics and international conventions.- Appendix. Tables.-Technical dictionary.- Bibliography.- References for figures.- Subject index.

Fields of interestForensic Medicine; Traumatic Surgery; Emergency Medicine



M. Korenkov, Kreiskrankenhaus Eschwege, Germany (Ed.)

Bariatric SurgeryTechnical Variations and Complications

The increasing prevalence of obesity in many countries means that it should now be considered a pandemic. It is widely recognized that obesity increases the risk of a variety of life-threatening conditions, including heart disease, diabetes, and hypertension. Bariatric surgery is often the most effective way to treat such morbid obesity. Nevertheless, while various bariatric procedures have been proposed, to date standards have been lacking. In this book, leading experts from around the world discuss all aspects of bariatric surgery and present their own favored versions of surgical procedures with the aid of informa-tive illustrations. Technical nuances are carefully described, and detailed attention is devoted to potential complications and how to avoid them. The expertise of the authors and the range of techniques considered guarantee that both trainees in bariatric surgery and experienced surgeons will find this book to be an invaluable source of infor-mation and guidance in their daily work.

Features 7 A comprehensive source of information and guidance on a wide range of bariatric surgical procedures 7 Describes technical nuances in detail and explains how to avoid potential compli-cations 7 Written by acknowledged experts from around the world 7 Invaluable for both trainees in bariatric surgery and experienced surgeons

Contents From the content: History of Bariatric Surgery.- Gastric Banding.- Gastric Bypass, Sleeve Resec-tion.- Duodenal Switch, New Techniques.- etc.

Fields of interestSurgery; Gastroenterology



Due November 2011

2011. XV, 185 p. 27 illus., 8 in color. (Methods in Molecular Biology, Volume 797) Hardcover

7 € 94,95 | £85.507 * € (D) 101,60 | € (A) 104,45 | sFr 136,50ISBN 978-1-61779-339-4

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Available

1st edition 2011. Approx. 500 p. 234 illus. Hardcover

7 € 179,95 | £162.007 * € (D) 192,55 | € (A) 197,94 | sFr 258,00ISBN 978-3-642-20355-8

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Due September 2011


7 € 139,95 | £126.007 * € (D) 149,75 | € (A) 153,94 | sFr 201,00ISBN 978-3-642-16244-2

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P. N. Lara, Jr., University of California School of Medi-cine, Sacramento, CA, USA; E. Jonasch, University of Texas MD Anderson Cancer Center, Houston, TX, USA (Eds.)

Kidney CancerPrinciples and Practice

This interdisciplinary textbook encompasses all clinically relevant aspects of the disease and is designed to be as user-friendly as possible in order to meet the needs of the busy practitioner.

Features 7 User-friendly comprehensive interdisciplinary textbook 7 Covers epidemiology, molecular biology, pathology, diagnosis, clinical features, staging, prognostic factors, surgery, systemic therapy, and emerging investigational approaches, etc. 7 Includes boxed sections presenting essen-tial ‘take home’ points and patient-oriented cases 7 Written by an international group of experts

Contents Epidemiology and biology: Rencal cell cancer (RCC) epidemiology. Pathology of RCC. Molecular biology of RCC. Prognostic and predictive biomarkers.- Clinical considerations: Clinical presentation and staging.- Surgical and local control modalities: Surgical approaches to early stage RCC. Palliative debulking nephrectomy in advanced stage RCC. Metastasectomy. Energy ablative techniques in RCC. Radiation therapy in RCC.- Systemic therapy considerations: Cytokines and other immune therapies in RCC. Anti-VEGF therapy in RCC. The role of mTOR inhibitors and PI3K pathway blockade in RCC. Sequential versus combination strategies. Presurgical therapy. Toxicity management for patients on targeted therapy. Emerging agents in RCC.

Fields of interestOncology; Surgical Oncology; Cancer Research



A. Larner, Walton Centre for Neurology and Neuro-surgery, Liverpool, UK

Teleneurology by Internet and TelephoneA Study of Medical Self-help

Medical information is now widely available on the Internet and through telephone helplines such as NHS Direct and the focus on patient self care is likely to increase. Clinicians in all specialties will often encounter patients who have made self-directed searches for medical information prior to the clinical encounter. Teleneurology by Internet and Telephone is a study of patient information-seeking behaviour in neurology patients prior to referral from primary to secondary care. The book analyses frequency of Internet access and use, and of telephone helpline awareness and use. It also explores use of these modalities over time, use according to patient gender and age and by gender and age over time.

Features 7 Pragmatic study, rooted in clinical practice, based in district general hospital clinics with findings widely applicable to clinicians’ day-to-day practice and succinct conclusions. 7 Simple methodology and analysis to make statistics more accessible to the reader. 7 Internet and telephone helplines contextualized in field of telemedicine to assist the reader to place the current work in the context of prior developments in telemedicine.

Contents Introduction.- Objectives, Methods, and Analysis.- Teleneurology by Internet.- Teleneurology by Telephone: NHS Direct.- Summary.- Bibliography.- References.

Fields of interestNeurology; Public Health/Gesundheitswesen



S. Lennquist, University of Linköping, Sweden (Ed.)

Medical Response to Major Incidents and DisastersA Practical Guide for All Medical Staff

This book, written by members of the core faculty responsible for European courses on Medical Response to Major Incidents (MRMI), is a prac-tical guide for all medical staff on how to respond to a wide range of disaster scenarios.

Features 7 Practical guide that covers the full range of disaster scenarios and is relevant to all medical staff 7 Addresses the entire spectrum of response from command and coordination through to the management of individual casual-ties 7 Will prove an invaluable aid to medical and nursing students, ambulance crew, and mili-tary personnel as well as medical specialists

Contents The major incident – definitions and demands on the health care system.- Major incidents: Examples and experiences.- The prehospital response.- Triage.- The hospital response.- Management of dead victims.- Incidents caused by physical trauma.- Incidents caused by fire and toxic gases.- Incidents in cold and wet environments.- Inci-dents caused by hazardous material.- Incidents caused by irradiation.- Infectious diseases and biological weapons.- Incidents caused by changes in nature and climate.- Combat casualty manage-ment.- Terrorist attacks on the civilian commu-nity.- Scoring systems related to outcome in severe injuries.- Psychological crisis support in major incidents.- Education and training.- Methodolog-ical development and research.

Fields of interestTraumatic Surgery; Emergency Medicine; Surgical Orthopedics



Due March 2012

2012. 190 p. 68 illus., 34 in color. Hardcover


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Due August 2011

2011. XII, 61 p. 16 illus., 8 in color. Hardcover

7 € 99,95 | £90.007 * € (D) 106,95 | € (A) 109,95 | sFr 143,50ISBN 978-0-85729-690-0

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Due October 2011

2012. VII, 399 p. 178 illus., 175 in color. Hardcover

7 € 99,95 | £90.007 * € (D) 106,95 | € (A) 109,95 | sFr 143,50ISBN 978-3-642-21894-1

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A. Luna, Clinica Las Nieves, Jaén, Spain; R. Ribes, Hospital Reina Sofia, Cordoba, Spain; J. A. Soto, Boston Medical Center, Boston, MA, USA

Diffusion MRI Outside the BrainA Case-Based Review and Clinical Applications

Recent advances in MR technology permit the application of diffusion MRI outside of the brain. In this book, the authors present cases drawn from daily clinical practice to illustrate the role of diffu-sion sequences, along with other morphological and functional MRI information, in the work-up of a variety of frequently encountered oncological and non-oncological diseases. Breast, musculo-skeletal, whole-body, and other applications are covered in detail, with careful explanation of the pros and cons of diffusion MRI in each circum-stance.

Features 7 Uses cases drawn from daily clinical practice to illustrate the increasing role of diffusion MRI outside the brain 7 Examines breast, musculosk-eletal, whole-body, and other applications in detail, covering a variety of frequently encountered onco-logical and non-oncological diseases 7 Considers applications likely to emerge in the near future 7 Contains a wealth of high-quality illustrations

Contents Diffusion MRI techniques: basic and advanced concepts.-Quantification and postprocessing.-Avoiding artifacts and identification of pitfalls in DWI.-DWI at 3T.-Liver.-Pancreas and biliary system.-Gastrointestinal system.-Rectum and anal cana.-Kidneys and urinary system.-Prostate.-Uterus, cervix and vagina.-Adnexa.-Whole-body applications.-Musculoskeletal applications.-Breast.-Neck and thorax.

Fields of interestImaging / Radiology; Oncology



P. W. Macfarlane, University of Glasgow, Glasgow, UK; A. v. Oosterom, Ecole Polytechnique Federale de Lausanne, Switzerland; M. Janse, Academisch Medisch Centrum, Nijmegen, The Netherlands; P. Kligfield, Cornell University, New York, NY, USA; J. Camm, St George’s Hospital Medical School, London, UK; O. Pahlm, University of Lund, Lund, Sweden (Eds.)

Basic ElectrocardiologyCardiac Electrophysiology, ECG Systems and Mathematical Modeling

Features 7 The complete electrocardiography reference work in clinician friendly volumes 7 Takes the reader from research and the laboratory bench through to the management of patients at the bedside. 7 All current available knowledge on the application, uses and value of the ECG

Contents Section I: Introduction.- The Coming of Age of Electrocardiology.- Introductory Physics and Mathematics.- Section II: Cardiac Electrophysi-ology.- Cellular Electrophysiology.- Activation of the Heart.- Genesis of the Electrocardiogram.- Section III: Mathematical Modeling.- Macroscopic Source Descriptions.- The Equivalent Double Layer: Source Models for Repolarization.- The Forward Problem of Electrocardiography.- The Inverse Problem of Electrocardiography.- Section IV: Electrocardiographic Lead Systems and Recording Techniques.- Lead Theory.- Lead Systems.- ECG Instrumentation: Application and Design.

Fields of interestCardiology; Medicine/Public Health, general




ElectrocardiologyComprehensive Clinical ECG

New edition of the classic complete reference book for cardiologists and trainee cardiologists on the theory and practice of electrocardiography, one of the key modalities used for evaluating cardiology patients and deciding on appropriate management strategies.


Contents Section V: Clinical Electrocardiography.- The Normal Electrocardiogram and Vetorcardio-gram.- Conduction Defects.- Enlargement and Hypertrophy.- Myocardial Infarction.- Ventricular Repolarization: Theory and Practice in Non-Isch-emic Myocardium.- Ventricular Repolarization in Myovardial Ischemia and Myocardial Infarction: Theory and Practice.- The QT Interval.- Miscel-laneous Electrocardiographic Topics.- The Electro-cardiogram in Congenital Heart Disease.- Electro-cardiography in Adult Congenital Heart Disease.

Fields of interestCardiology



Due October 2011


7 € 129,95 | £117.007 * € (D) 139,05 | € (A) 142,94 | sFr 186,50ISBN 978-3-642-21051-8

9<HTOGPC=cbafbi>

Due October 2011

Only available in print

2012. XVIII, 480 p. 250 illus. Softcover

7 € 59,95 | £53.997 * € (D) 64,15 | € (A) 65,95 | sFr 86,00ISBN 978-0-85729-870-6

9<HTLIQH=cjihag>

Due August 2011


2012. XII, 604 p. 401 illus. Softcover

7 € 59,95 | £53.997 * € (D) 64,15 | € (A) 65,95 | sFr 86,00ISBN 978-0-85729-873-7

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Specialized Aspects of ECGNew edition of the classic complete reference book for cardiologists and trainee cardiologists on the theory and practice of electrocardiography, one of the key modalities used for evaluating cardiology patients and deciding on appropriate management strategies.


Contents Section IX: Specialized Aspects of Electrocardi-ography Part 2.- Exercise Electrocardiography and Exercise Testing.- Computer Analysis of the Electrocardiogram.- Pacemaker Electrocardi-ography.- The Signal Averaged Electrocardio-gram.- Electrocardiography in Epidemiology.- The Dog Electrocardiogram: A Critical Review.- The Mammalian.- Electrocardiogram: Comparative Features.- 12 lead Vectocardiography.- Magneto-cardiography.- Polarcardiography.

Fields of interestCardiology



D. Minerva, Gruppo Editoriale L’Espresso, Milano, Italy

Il fuoco dentroLe malattie infiammatorie croniche dell’intestino Colloquio con Silvio Danese e Marco Greco

Colpiscono circa 170 mila italiani, con un trend in forte ascesa. Si chiamano Malattia di Crohn e colite ulcerosa: malattie autoimmuni, ovvero causate da un errore del sistema immunitario che si scatena contro se stesso. Perché? Come fermare questa furia distruttiva? Sono stati fatti grandi passi avanti ma molto resta ancora da scoprire e molte sono le questioni controverse: dalle cause della malattia ai metodi di diagnosi più tempestiva, alle terapie. Le malattie autoimmuni dell’intestino colpiscono in giovane età, tra i 15 e i 45 anni, hanno un impatto molto negativo sulla qualità della vita di chi si ammala e pongono questioni di primissimo piano: come si convive con una diagnosi di questo tipo, qual è il migliore accesso alle cure, quali le disposizioni di legge che facilitano la vita dei malati. Questo libro vuole raccontare la vita e la battaglia quotidiana delle persone colpite da queste malattie, le scelte che devono fare e gli ostacoli che si trovano ad affrontare, dal punto di vista di uno dei massimi esperti mondiali della materia, Silvio Danese, e da quello di un giovane paziente, Marco Greco, che ha trasformato la sua lotta quotidiana in una battaglia condotta a nome di tutti i malati.

Features 7 Originalità 7 Applicatività con situazioni reali e concrete 7 Riflessioni

Fields of interestGastroenterologia; Chirurgia colorettale; Onco-logia chirurgica


Type of publicationMonografia

P. M. Nadkarni, Yale University, New Haven, CT, USA

Metadata-driven Software Systems in BiomedicineDesigning Systems that can adapt to Changing Knowledge

Contents 1. What is metadata? Types of metadata.- Descrip-tive (interpreted by humans).- Technical (utilized by software).- Some metadata shows characteris-tics of both.- How metadata is represented.- Why use metadata to build biomedical systems? Caveat: Metadata-driven systems are initially harder to build, Building for change: flexibility and main-tainability, Elimination of repetitious coding tasks, Case Study: Table-driven approaches to software design.- 2. Metadata for supporting electronic medical records.- The Entity-Attribute-Value (EAV) data model:.- Why EAV is problematic without metadata-editing capabilities: the TMR experience.- Pros and Cons of EAV: When not to use EAV.- How metadata allows ad hoc query to be data-model agnostic.- Transactional opera-tions vs. warehousing operations.- Case Study: The I2B2 clinical data warehouse model.- Providing end-user customizability, Case Study: EpicCare Flowsheets.- 3. Metadata for clinical study data management systems (CSDMS).- Critical differ-ences between an EMR and a CSDMS.- Essential elements of a CSDMS.- HTML-based vs. non-Web interfaces: pros and cons.- Case Study: Metadata for robust interactive data validation.- Metadata and the support of basic bioscience research.- Object dictionaries and synonyms: the NCBI Entrez approach.- Fundamentals of object-oriented modeling: the use of classes.- Case study: representing neuroscience data: SenseLab.- Case study: managing phenotype data.- 4....

Fields of interestHealth Informatics; Biomedicine general; Health Administration



Due August 2011


2012. XII, 388 p. 291 illus. Softcover

7 € 59,95 | £53.997 * € (D) 64,15 | € (A) 65,95 | sFr 86,00ISBN 978-0-85729-879-9

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Pubblicazione prevista per il mese di luglio 2011

2011. 110 pagg. Brossura


9<HTTIPH=acaghc>

Available


7 € 69,95 | £62.997 * € (D) 74,85 | € (A) 76,95 | sFr 100,50ISBN 978-0-85729-509-5

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K. Nouri, University of Miami, FL, USA (Ed.)

Mohs Micrographic Surgery

Contents Chapter 1: Historical Perspective of Mohs Micro-graphic Surgery.- Section I: Fundamentals of Mohs Micrographic Surgery.- Chapter 2: General Indications for Mohs Micrographic Surgery -Tumor Location (high risk anatomical location; tissue conservation priority) -Tumor Size -Deep Structure Involvement -Recurrent Tumor -Positive margins after surgical excision -Tumor type/histo-logical differentiation -Irradiated skin.- Chapter 3: Pre-operative Evaluation.- Chapter 4: The Mohs Micrographic Surgery Operative Room Set-up.- Chapter 5: Anesthesia Considerations: Local versus Regional.- Chapter 6: Surgical Anatomy for Mohs Micrographic Surgeons.- Chapter 7: The Fixed-Tissue Mohs Micrographic Surgical Tech-nique -Mapping -Instrumentation and sutures.- Chapter 8: The Fresh-Tissue Mohs Micrographic Surgical Technique -Mapping -Instrumentation and sutures.- Chapter 9: Special Considerations for Mohs Micrographic Surgery in Organ transplant recipients.- Chapter 10: Mohs Micrographic Surgery in Ethnic Skin.- Chapter 11: Mohs Micro-graphic Surgery and Genodermatoses.- Chapter 12: Nursing Interventions.- Section II: Labora-tory Processing.- Chapter 13: Histopathology Laboratory Set-up and Necessary Instruments.- Chapter 14: Tissue Specimen Transport and Initial Processing.- Chapter 15: Cryostat Preparation of Slides.- Chapter 16: Staining Preparation of Slides.- Chapter 17: Histopathologic Interpretation of Mohs Slides.- Chapter 18: Tissue Specimen Docu-mentation/Record-Keeping/Storage.- Section III: Mohs Micrographic Surgery by tumor and site....

Fields of interestDermatology; Plastic Surgery; Otorhinolaryn-gology



M. Pescatori, University of Rome, La Sapienza, Rome, Italy

Postoperative Complications in ColoproctologyPrevention and Treatment

The volume is authored by a colorectal surgeon with long-standing clinical and scientific experi-ence and is devoted to the management of complications following surgery of the anorectum and the pelvic floor. It is aimed not only at general surgeons, perineologists and, of course, proctologists, but also at gastroenterologists, endoscopists, radiologists and physiotherapists, i.e. those who may be involved in both diagnosis and cure whenever an adverse event, either unpredictable or potentially preventable, causes an intra- or postoperative, early or late, mild or life-threatening complication. Severe bleeding, dehiscence, perforation, anorectal stricture, fecal incontinence, and even caval vein thrombosis, fatal Fournier gangrene and pneumomediastinum may occur after anal surgery. The incidence, pathogen-esis prevention and treatment of such events are discussed in detail in 10 chapters with 30 tables, 200 illustrations and more than 1000 references. Both conventional procedures and recent innova-tions are reported. “Unforgettable clinical cases (complications with litigation)” and “Tips and Tricks” are sections increasing the appeal of this book.

Features 7 Complications in Coloproctology 7 Unfor-gettable Clinical Cases (with complications) 7 Medico-legal implications Tips and Tricks

Fields of interestProctology; General Surgery



M. Pescatori, Università di Roma La Sapienza, Italy

Prevenzione e trattamento delle complicanze in chirurgia proctologica

Questo libro su anoretto e pavimento pelvico è indirizzato soprattutto ai chirurghi generali e ai proctologi. Ma anche a radiologi, gastroenterologi, endoscopisti e fisioterapisti. Tutti coloro cioè che sono coinvolti nella gestione del paziente in quel momento critico in cui un evento, imprevisto o magari prevedibile, causa un problema diagnostico o terapeutico. Le complicanze sono presentate e discusse in dettaglio, con la loro patogenesi, prevenzione e cura, usando nuovi metodi interat-tivi, come gli interventi “in diretta”, i “trucchi del mestiere” e le complicanze “memorabili”, quasi tutti ampiamente illustrati. In alcuni punti lo stile è quello del racconto: colloquiale e attraente per chi legge. Si parla di chirurgia tradizionale e di “inno-vations”. L’approccio è olistico, il paziente è visto nella sua totalità: una ferita può non guarire per ipopituitarismo e un reintervento può fallire per deficit psicosomatico. L’impostazione è scientifica, “evidence based”, ma dà importanza all’eclettismo ragionato e alla chirurgia su misura. Circa mille le voci bibliografiche, in gran parte dell’ultimo decennio. Trenta le tabelle. Più di 200 le figure, tra schemi, “imaging”, campi operatori, foto ambulato-riali e disegni.

Features 7 Complicanze in coloproctologia 7 Casi clinici memorabili (con complicanze) 7 Implicazioni medico-legali Trucchi del mestiere

Fields of interestProctologia; Chirurgia generale


Type of publicationMonografia

Due November 2011



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Due July 2011



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Pubblicazione prevista per il mese di settembre 2011

2011 2011. 240 pagg. 150 figg., 100 a colori. Brossura


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H. A. Peterson, Mayo Clinic, Rochester, MN, USA

Physeal Injury Other Than Fracture

This book documents all the ways a growth plate can be damaged, other than fracture. This damage can be inflicted by a wide variety of insults, most of which are uncommon occurrences. They all, however, have two similar characteristics: normal roentgenographs at the time of insult and premature complete or partial arrest noted weeks, months, or years later. Because of this delay, the arrest is often not suspected or recognised early. The resulting bone deformity and relative shortening usually go undetected until corrective surgery is needed. This book emphasises etiology, diagnosis, and treatment of these injuries.

Features 7 Brings together all the information concerning growth plate injuries into one readily accessible source 7 Based on the unique resources of the Mayo Clinic regarding patient follow-up 7 Well structured and heavily illustrated

Contents Vascular Deficiency.- Disuse.- Infection.- Tumor.- Metabolic.- Neural.- Cold (frostbite).- Heat (burn).- Electric.- Compression.- Distraction.- Stress.- Irradiation.- Light Waves.- Sound Waves.- Shock Waves.- Atmospheric Pressure.- Oxygen.- Developmental.- Surgical.- Unknown.

Fields of interestOrthopedics; Pediatrics; Imaging / Radiology



M. Pisani, Yale University School of Medicine, New Haven, CT, USA (Ed.)

Aging and Lung DiseaseA Clinical Guide

People age 65 and older are the fastest growing segment of the U.S. population. In the 2010 census 16% of the population, 50 million people, were age 65 and older. That number is projected to increase to 66 million by the year 2050. Life expectancy has also increased, with recent CDC reports indicating life expectancy at 77.9 years.

Features 7 Discusses key physiologic changes in lung structure and function in older adults 7 Provides state-of-the-art reviews of epide-miology, disease presentation, and diagnosis and management as it pertains to older patients 7 Covers special considerations in lung-disorder management in older patients

Contents Physiologic Changes in the Aging Lung.- Allergy and Immunology of the Aging Lung.- Physi-ologic Changes in Sleep with Aging.- Chronic obstructive pulmonary disease (COPD) in Older Patients.- Lung Cancer in Older Patients.- Pulmo-nary Hypertension in Older Patients.- Pulmonary Embolism in Older Patients.- Obstructive Sleep Apnea in Older Patients.- Sleep Disorders in Older Patients.- Non-tuberculous Mycobacte-rial Infection in Older Patients.- Interstitial Lung Disease in Older Patients.- Lung Disease in Older Patients with HIV.- Special Considerations in Lung Transplantation in Older Patients.- Assessment of Functional and Cognitive Status in Older Patients with Lung Disease.- Addressing End-of-Life Issues in Older Patients with Lung Disease.

Fields of interestPneumology/Respiratory System; Internal Medi-cine; Primary Care Medicine



D. G. Poitout, Centre Hospitalo Universitaire Marseille Nord, Marseille, France; H. Judet, Clinique Jouvenet, Paris, France (Eds.)

Mini-invasive surgery of the hip

The mini-invasive surgery has become in recent years a practical necessity for reducing the risk of infection, the importance of blood loss and volume of implants. At the hip it became neces-sary to make small incisions requiring the use of appropriate equipment combined with the full knowledge of the local anatomy.

Features 7 Contains surgery video 7 Experts from all over Europe 7 A reference book on MIS of the hip

Contents Total hip arthroplasty through an Anterior Hueter Minimally Invasive approach on Orthopaedic Table.- Total hip arthroplasty Navigated through an Anterior Hueter Minimally Invasive approach on Orthopaedic Table.- MIS of the Hip through an Anterior approach on Lateral position.- MIS of the Hip through Smith Petersen approach on lateral position with mini-stem.- MIS of the Hip through anterior approach. Approach on Supine position.- MIS of the Hip through Watson Jones approach on Supine position.- MIS of the Hip through a Trans-trochant. Approach on Lateral position.- MIS of the Hip through a Direct Lateral approach on lateral position.- MIS of the Hip through Mini post approach on Lateral position.- MIS Hip resurfacing through an anterior approach on Supine position.- MIS Hip resurfacing posterior approach.- MIS and CAS with posterior approach.- Mini Stem with CAS.

Fields of interestMedicine/Public Health, general; Orthopedics; Surgical Orthopedics



Due November 2011

2012. XVI, 400 p. 109 illus. Hardcover


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Due November 2011

2011. XII, 354 p. 28 illus., 16 in color. (Respiratory Medi-cine) Hardcover

7 € 159,95 | £144.007 * € (D) 171,15 | € (A) 175,94 | sFr 229,50ISBN 978-1-60761-726-6

9<HTMGLH=gbhcgg>

Due December 2011

2012. Approx. 280 p. With DVD. Softcover

7 € 59,95 | £53.997 * € (D) 64,15 | € (A) 65,95 | sFr 86,00ISBN 978-2-287-79930-3

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P. M. Prendergast, Venus Medical Beauty, Dublin, Ireland; M. A. Shiffman, Tuscin,CA, USA (Eds.)

Aesthetic MedicineArt and Techniques

The Aesthetic Medicine: Art and Techniques provides step-by-step instructions in the proce-dures and techniques commonly employed in aesthetic medicine. The book is divided into four parts, the first two of which offer an introduction to aesthetic medicine and discuss preoperative assessment and treatment.

Features 7 Step-by-step guide to the procedures and tech-niques commonly employed in aesthetic medicine 7 Includes numerous high-quality illustrations and color photographs 7 Suitable for both begin-ners and experienced practitioners

Contents From the contents: AESTHETIC MEDICINE.- Defining.- Ethical Aspects.- PREOPERATIVE.- Clinical Assessment Of Facial Aging.- Weight Management.- Phytotherapy.- Skin Imaging.- Cosmeceuticals For Maximizing Treatment Of The .- Aging Face.- CUTANEOUS PROCEDURES .- Local Regional Anesthesia.- Botulinum Toxins.- Microdermabrasion.- Dermabrasion.- Cryo-therapy.- Chemical Peel Skin Resurfacing.- Frac-tional Laser Resurfacing.- Facial Rejuvenation With Poly-L-Lactic .- Acid (Sculptra).- Intense Pulsed Light (Ipl.- Laser Treatment .- Sclero-therapy Varicose Veins.- Cellulite: Etiology, Classi-fication, Pathology, .- And Treatment.- SHAPING FACE AND BODY.- Breast Augmentation With Hyaluronic Acid.- Potential Risks And Complica-tions Of Injectable Alloplastic Facial Fillers.- Facial Augmentation With Autologous Fat.- Lipoplasty of The Face Using Vaser.- Suture Lifting Techniques.- Emerging Technologies.- Index.

Fields of interestPlastic Surgery; Dermatology; Otorhinolaryn-gology



M. Ramos-Casals, Hospital Clínic, Barcelona, Spain; J. H. Stone, Massachusetts General Hospital, Boston, MA, USA; H. M. Moutsopoulos, National University of Athens, Greece (Eds.)

Sjögren’s SyndromeDiagnosis and Therapeutics

Contents Epidemiology.- Genetics and Proteomics.- Immu-nopathogenesis.- Viruses.- Etiopathogenic role of B-cells.- Oral involvement.- Ocular involve-ment.- Ear, nose and throat involvement.- Fatigue, fibromyalgia and other general symptoms.- Musculoskeletal involvement.- Non-vasculitic cutaneous involvement.- Vasculitis.- Cardiovas-cular involvement.- Pulmonary involvement.- Raynaud phenomenon.- Gastrointestinal involve-ment.- Autoimmune liver involvement.- Pancreatic involvement.- Nephro-urological involvement.- Central nervous system involvement.- Peripheral neuropathy.- Autonomic neuropathy.- Endocrine involvement.- Gynecological and obstetrical complications.- Laboratory abnormalities.- Diag-nostic procedures (I).- Diagnostic procedures (II).- Immunological tests.- Classification criteria.- Measurement of chronicity and activity.- Measure-ment of quality of life.- Association with other autoimmune and rheumatic diseases.- Cancer.- Prognostic factors and survival.- SS in primary care.-Treatment of sicca features.- Treatment of B-cell lymphoma.- Classic immunosuppressive and immunomodulatory drugs.- New immunosup-pressive and immunomodulatory drugs.- B-cell targeted therapies.- Other biological therapies.- Experimental therapies.

Fields of interestRheumatology; Internal Medicine; General Prac-tice / Family Medicine



D. T. Schneider, Westfälisches Kinderzentrum, Dortmund, Germany; I. B. Brecht, University Hospital Erlangen, Germany; T. A. Olson, Emory University, Atlanta, GA, USA; A. Ferrari, Istituto Nazionale dei Tumori, Milan, Italy (Eds.)

Rare Tumors In Children and Adolescents

This is the first book to be devoted exclusively to rare tumors in children and adolescents, and its aim is to provide up-to-date information on their diagnosis and clinical management. The opening section addresses general issues including epidemiology, risk factors/etiology, biology and genetics, early detection, and screening.

Features 7 First book to be devoted exclusively to rare tumors in children and adolescents 7 Explains the differential diagnostic assessment appropriate at each tumor site, enabling the clinician to take rare entities into account 7 Provides detailed therapeutic guidelines for each of the rare tumors discussed 7 Written by a multidisciplinary group of specialists in the field

Contents Introduction: Rare Cancers: A different perspec-tive on oncology.-Epidemiology and etiology of rare cancers.-The national and international rare tumor study groups.-Information and resources for patients with rare tumors.-Rare tumors of the head and neck region.-Rare tumors of the thorax.-Rare tumors of the gastrointestinal tract.-Germ cell tumors and genitourinary tumors.-Rare tumors of the peripheral nervous system.- Rare tumors of the skin and subcutaneous tissue.-Rare mesenchymal tumors.-Tumors of unkown primary site.-Rare tumors as second malignancies.

Fields of interestOncology; Surgical Oncology; Pediatrics



Due September 2011

2011. XIII, 629 p. 414 illus., 405 in color. Hardcover

7 € 159,95 | £144.007 * € (D) 171,15 | € (A) 175,94 | sFr 229,50ISBN 978-3-642-20112-7

9<HTOGPC=cabbch>

Due October 2011

2011. XII, 633 p. 92 illus., 66 in color. Hardcover

7 € 99,95 | £90.007 * € (D) 106,95 | € (A) 109,95 | sFr 143,50ISBN 978-0-85729-946-8

9<HTLIQH=cjjegi>

Due October 2011

2012. IV, 647 p. 174 illus., 139 in color. (Pediatric Oncology) Hardcover

7 € 179,95 | £162.007 * € (D) 192,55 | € (A) 197,94 | sFr 258,00ISBN 978-3-642-04196-9

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G. R. Scuderi, Insall Scott Kelly Institute for Ortho-paedics and Sports Medicine, New York, NY, USA; A. J. Tria, Clinical Professor of Orthopaedic Surgery, Robert Wood Johnson Medical School, Piscataway, NJ, USA (Eds.)

Minimally Invasive Surgery in OrthopedicsKnee Handbook

Features 7 Contains valuable chapters from Minimally Invasive Surgery in Orthopedics at a newly afford-able price 7 Fully illustrated 7 Focused specifi-cally on the knee

Contents MIS unycondylar arthroplasty: the bone-sparing technique.- Minimally invasive surgery for unicondylar knee arthroplasty: the intramed-ullary technique.- The extramedullary tensor technique for unicondylar knee arthroplasty.- MIS unicondylar knee arthroplasty with extramed-ullary technique.- MIS arthroplasty with the UniSpacer.- MIS total knee arthroplasty with the limited medial parapatellar arthrotomy.- MIS TKA with a subvastus approach.- Mini-midvastus total knee arthroplasty.- Minimally invasive total knee arthroplast.- Quadriceps-sparing total knee arthroplasty.- Minimally invasive quadriceps-sparing total knee replacement preserving the posterior cruciate ligament.- Bi-unicompartmental knee prostheses.- MIS patellofemoral arthroplasty.- Round table discussion of MIS total knee arthro-plasty.- Computer assisted orthopedic surgery (CAOS): pros and cons.- Minimally invasive total knee arthroplasty with image-free navigation.- The utility of robotics in total knee arthroplasty.- Elec-tromagnetic navigation in total knee arthroplasty.- Robotics in total knee arthroplasty.

Fields of interestOrthopedics; Surgical Orthopedics



G. R. Scuderi, Insall Scott Kelly Institute for Ortho-paedics and Sports Medicine, New York, NY, USA; A. J. Tria, Department of Orthopedic Surgery, Robert Wood Johnson Medical School, Piscataway, NJ, USA (Eds.)

Minimally Invasive Surgery in OrthopedicsUpper Extremity Handbook

Minimally Invasive Surgery in Orthopedics: The Upper Extremity Handbook contains all of the valuable chapters from Section 1 of Scuderi and Tria’s 2010 hardcover reference.

Features 7 Contains valuable chapters from Minimally Invasive Surgery in Orthopedics at a newly afford-able price 7 Fully illustrated 7 Focused specifi-cally on the upper extremities

Contents What is minimally invasive surgery and how do you learn it?.- Overview of shoulder approaches.- Mini-incision bankart repair.- Mini-open rotator cuff repair.- Minimally invasive treatment of greater tuberosity fractures.- Mini-incision fixation of proximal humeral four-part fractures.- Mini-incision shoulder arthroplasty.- Overview of elbow approaches.- Mini-incision medial collateral liga-ment reconstruction of the elbow.- Mini-incision distal biceps tendon repair.- Minimally invasive approaches for complex elbow trauma.- Minimally invasive approaches for lateral epicondylitis.- Overview of wrist and hand approaches.- Mini-mally invasive surgical fixation of distal radius fractures.- Minimally invasive fixation for wrist fractures.- Endoscopic and minimally invasive carpal tunnel and trigger finger release.- Round table discussion of minimally invasive surgery upper extremity cases.

Fields of interestOrthopedics; Surgical Orthopedics; Minimally Invasive Surgery



H. Singh, J. Neutze, Penn State College of Medicine, Hershey, PA, USA (Eds.)

Radiology FundamentalsIntroduction to Imaging & Technology

Contents Patient Radiation Safety and Risk.- Introduc-tion to Radiology Concepts.- Conventional Radiology.- Ultrasound.- Computed Tomog-raphy.- MRI.- Nuclear Medicine.- Cardiovas-cular and Interventional Radiology.- Heart and Mediastinum .- Lateral Chest.- Pulmonary Mass Lesions.- Air Space Disease.- Interstitial Disease.- Atelectasis.- Pulmonary Vasculature.- Pulmonary Edema.- Pneumothorax.- Miscellaneous Chest Conditions.- Tubes and Lines.- Breast Imaging.- Women’s Ultrasound.- Women’s Health Interven-tions.- Abdominal Calcifications.- Abnormal Air Collections in the Abdomen.- Barium Studies of the Upper GI Tract.- Barium Enema CT Colo-nography.- Bowel Obstruction.- Inflammatory Bowel Disease.- Defecography.- Intra-abdominal Lymphadenopathy.- The Gallbladder.- Abdominal Pelvic Pain Evaluation.- Imaging of the Trauma Patient.- Concerning Lesions.- Incidental Lesions.- Radionucleotide Evaluation of GI Bleeding.- Radionucleotide Bone Imaging.- Lung Ventilation and Perfusion Imaging.- Radionucleotide Cardiac Imaging.- F-18 FDG Positron Emission Tomog-raphy.- Diagnostic Arteriography.- Pulmonary Arteriography IVC Filter Placement.- Percuta-neous Nephrostomy Placement.- TIPS.- Central Venous Access.- Fractures - Part 1.- Fractures - Part 2.- Arthritides.- Bone Tumor Character-stics.- CNS Anatomy.- The Cervical Spine.- Head Trauma.- Stroke.- Headache and back pain.- Radi-ology.

Fields of interestImaging / Radiology; Diagnostic Radiology; Medi-cine/Public Health, general


Type of publicationGraduate/Advanced undergraduate textbook

Due November 2011


2012. VIII, 300 p. 199 illus., 101 in color. Softcover

7 € 59,95 | £53.997 * € (D) 64,15 | € (A) 65,95 | sFr 86,00ISBN 978-1-4614-0678-5

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Due November 2011


2011. IX, 245 p. 176 illus., 101 in color. Softcover

7 € 59,95 | £53.997 * € (D) 64,15 | € (A) 65,95 | sFr 86,00ISBN 978-1-4614-0672-3

9<HTMERB=eaghcd>

Due December 2011

4th Edition 2012. CD, 20 p. 274 illus., 23 in color. Softcover


9<HTMERB=eajede>





J. Skyler, Miami Miller School of Medicine, Miami, FL, USA (Ed.)

Atlas of DiabetesThis handbook is an invaluable resource for improving the management of diabetes. Chapters cover the fundamentals, including epidemiology, history and physical examination, and functional evaluations. Diabetes in children, adolescents, adults, and geriatrics are addressed. Differential diagnosis is emphasized, and evidence-based guidelines and patient-specific considerations aid the reader with injury evaluation and care. Notably, the book highlights the importance of understanding diabetic symptoms when deter-mining the source of illnesses. In addition, the text presents the spectrum of treatment options for diabetes.

Features 7 Provides cutting-edge research methodologies 7 Includes insightful analysis of trends in diabetes management 7 Written by field-leading experts in an approachable, figure-laden format

Contents Regulation of Insulin Secretion and Islet Cell Function.- Mechanisms of Insulin Action.- Consequences of Insulin Deficiency.- Type 1 Diabetes.- Management of Type 1 Diabetes.- Childhood Diabetes.- Pathogenesis of Type 2 Diabetes.- Management of Type 2 Diabetes Mellitus.- Diabetes and Pregnancy.- Mechanisms of Hyperglycemic Damage in Diabetes.- Manage-ment and Prevention of Diabetic Complica-tions.- Eye Complications of Diabetes.- Diabetes and the Kidney.- Diabetic Neuropathies.- Obesity Therapy.- Reversal of Diabetes: Islet Cell Trans-plantation.- Technology and Diabetes: Insulin Delivery Systems and Glucose Sensing.- Newer Diabetes Medications.

Fields of interestDiabetes; Pediatrics; Primary Care Medicine



R. O. Snyder, University of Florida, Gainesville, FL, USA; P. Moullier, Unité INSERM 649, Nantes, France (Eds.)

Adeno-Associated VirusMethods and Protocols

Today, progress in rAAV-mediated gene transfer is so robust that long-term, efficient, and regulatable transgene expression is reproducibly achieved in large animal models.

Features 7 Includes cutting-edge methods and proto-cols 7 Provides step-by-step detail essential for reproducible results 7 Contains key notes and implementation advice from the experts

Contents Adeno-Associated Virus Biology.- Design and Construction of Functional AAV Vectors.- AAV Capsid Structure and Cell Interactions.- Exploiting Natural Diversity of AAV for the Design of Vectors With Novel Properties.- Gene Therapy in Skeletal Muscle Mediated by Adeno-Associated Virus (AAV) Vectors.- AAV-Mediated Liver-Directed Gene Therapy.- Recombinant AAV Delivery to the Central Nervous System.- AAV Mediated Gene Therapy for Retinal Degenerative Diseases.- Adeno-Associated Virus Vector Delivery to the Heart.- Evaluation of the Fate of rAAV Genomes Following in vivo Administration.- Measuring Immune Responses to Recombinant AAV Gene Transfer.- Modification and Labeling of AAV Vector Particles.- AAV-mediated Gene Targeting.- Preclinical Study Design for rAAV.- Biodistribu-tion and Shedding of AAV Vectors.- Production and Purification of Recombinant Adeno-Associ-ated Vectors.- rAAV Vector Product Characteriza-tion and Stability Studies.- rAAV Human Trial Experience.

Fields of interestInfectious Diseases; Gene Therapy



R. Taylor, Oregon Health & Science University, Port-land, OR, USA

Medical WritingA Guide for Clinicians, Educators, and Researchers

The first edition of this book (titled “The Clini-cian’s Guide to Medical Writing”) has become a standard in its field and remains an indispensible reference for any clinician, academic physician, or health professional who wishes to hone their writing skills. However, since its publication in 2004, significant changes have taken place in the way medical professionals communicate with each other and the world.

Features 7 Comprehensive and easy to read Equally useful across all medical professions and specialties Fully revised to include information on grant writing, electronic publishing and other of-the-minute topics

Contents Getting started in medical writing.- Basic writing skills.- From page one to the end.- Technical issues in medical writing.- What’s special about medical writing?.- How to write a review article.- Case reports, editorials, letters to the editor, book reviews and other publication models.- Writing book chapters and books.- How to write a research protocol.- How to write a grant proposal.- How to write a report of a clinical research study.- Getting your writing published.- Appendix.

Fields of interestGeneral Practice / Family Medicine; Primary Care Medicine; Medicine/Public Health, general



Due November 2011

4th Ed. 2012. XII, 334 p. 505 illus., 384 in color. Hardcover

7 € 139,95 | £126.007 * € (D) 149,75 | € (A) 153,94 | sFr 201,00ISBN 978-1-4614-1027-0

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Due November 2011

2011. X, 395 p. 43 illus., 21 in color. (Methods in Molecular Biology, Volume 807) Hardcover

7 € 109,95 | £99.007 * € (D) 117,65 | € (A) 120,95 | sFr 158,00ISBN 978-1-61779-369-1

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Due September 2011

2nd Edition. 2011. 325 p. Softcover

7 € 29,95 | £26.997 * € (D) 32,05 | € (A) 32,95 | sFr 43,00ISBN 978-1-4419-8233-9

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A. Tinelli, Vito Fazzi Hospital, Lecce, Italy (Ed.)

Laparoscopic EntryTraditional Methods, New Insights and Novel Approaches

Features 7 Pictures and description of each method to entry Images and illustrations of entry related complication 7 Detailing of anatomical sections passed from methods, step by step - Reviewing tables and charts of the full literature 7 Sche-matic diagrams helping readers

Contents Anatomy of The Abdominal Wall And Vaginal Entry in Relation to Complications of Access and Injury in Laparoscopy.- Surgical Technique of Traditional Laparoscopic Access.- Laparoscopic Abdominal Entry by the Ternamian Threaded Visual System.- Initial Access to the Perito-neal Cavity for Laparoscopic Surgery in Obese Patients.- The Direct Optical Access: A Feasible, Reliable and Safe Laparoscopical Entry.- Robotic Assisted Surgery and Related Abdominal Entry.- Robotic-Assisted Surgery Entry In Gynecological Oncology.- Single Access Surgery - Less Is More?.- Reduced Port Surgery: Single Port Access to the Abdominal and Pelvic Cavity.- Minimally Invasive Gynecologic Surgery Evolving: Gas-Less Laparoscopic Inspection and Single Hole Surgery (Glishs).- First Abdominal Access in Gynaeco-logical Laparoscopy: Comparison Of Techniques.- Blind Entry at Gynaecological Laparoscopy is Substituted By Entry Under Sight – Complications in Conventional Laparoscopic Entry.- Natural Orifice Surgery – Surgical Procedures Through Natural Body Openings.- The Access In Natural Orifice Transvaginal Endoscopic Surgery.

Fields of interestGynecology; Urology/Andrology; Surgery



A. Tosti, University of Bologna, Bologna, Italy; P. E. Grimes, Vitiligo and Pigmentation Institute,LA, USA; M. P. De Padova, Università Bologna Policlinico, Bologna, Italy (Eds.)

Color Atlas of Chemical PeelsChemical peeling is a well-known method used to restore a more youthful appearance and improve dermatologic defects. This book is the first atlas on chemical peels and has been significantly revised and updated since the first edition so as to reflect the state of the art in the field.

Features 7 Fully updated since the first edition 7 Pres-ents the different peeling techniques with the aid of informative illustrations 7 Describes the treat-ment options appropriate for a variety of diseases and conditions, such as acne, rosacea, melasma, photoaging, postinflammatory hyperpigmenta-tion, actinic keratosis, and dark skin 7 An ideal reference tool for all who perform, or wish to start performing, chemical peels

Contents Types of Chemical Peels: Advantages/Disadvan-tages, an Illustrated Algorythms.- Modalities of Application: Glycolic Acid, Salicylic Acid, Pyruvic Acid, Trichloroacetic Acid, Phenol, Jessner’s Solution.- Combinations Peels: Jessner’s Solution + TCA, Salicylic Acid + TCA.- Home Peeling: a Combined Technique.- Combination of Peel-ings and Mesolift.- Combination of TCA and Microdermoabrasion.- Combination of TCA and Needling.- How to Choose the Best Peeling for the Patient: Acne, Photoaging, Melasma, Senile Lentigines, Postinflammatory Hyperpigmentation, Scarring, Rosacea, Actinic Keratosis, Dark Skin, Hand and Neck Rejuvenation.- Side Effects and Management.- Management of the Patient.

Fields of interestDermatology; Plastic Surgery; Nursing



Due November 2011

2012. XI, 368 p. 177 illus., 149 in color. Hardcover

7 € 99,95 | £90.007 * € (D) 106,95 | € (A) 109,95 | sFr 143,50ISBN 978-0-85729-979-6

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Due September 2011

2nd ed. 2011. 225 p. 300 illus. in color. Hardcover

7 € 139,95 | £126.007 * € (D) 149,75 | € (A) 153,94 | sFr 201,00ISBN 978-3-642-20269-8

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J. N. Alpert M. S. Badr J. D. Bisognano R. Connell ... · Normal Sleep.- Pharmacology of Sleep.-...

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