It’s a Boy!

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It’s a Boy!

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It’s a Boy!. Long-term Memory. Where does the dissociation between structures involved in LTM come from (in humans)?. Long-term Memory. Patient H.M. “Loss of Recent Memory After Bilateral Hippocampal Lesions”, Scoville and Milner (1957) - PowerPoint PPT Presentation

Transcript of It’s a Boy!

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It’s a Boy!

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Where does the dissociation between structures involved in LTM come from (in humans)?

Long-term Memory

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Long-term Memory

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Patient H.M.• “Loss of Recent Memory After Bilateral Hippocampal

Lesions”, Scoville and Milner (1957) • onset of epilepsy at age ten, perhaps due to bike

accident (wear a helmet!)

• 1953 - underwent temporal lobectomy to reduce seizure activity

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• severe anterograde amnesia• temporally graded retrograde amnesia

Patient H.M.

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Patient H.M.

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1. Memory and perceptual skills are dissociable.2. Lesions of the MTL produce amnesia for recent but not

remote events.3. There are multiple long-term memory systems in the brain.

Patient H.M.

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Long-term Memory

• What’s the one thing that all of these people have in common?

Lesions!

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Long-term Memory• What about normal memory?

• That is, memory in the “normal” brain

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Long-term MemoryThe theory is that the MTL is temporally involved in declarative memory in normal humans…

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Long-term Memory

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Long-term Memory

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Long-term Memory• functional imaging data from “normal” subjects confirms

lesion studies

• be skeptical!

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Long-term Memory• What would it be like to possess the ability to remember

everything?

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Long-term Memory• Case study of S. (Solomon Shereshevskii)

• Russian journalist

• never took any notes, recalled everything verbatim

• thought this was “normal”

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Long-term Memory• Alexander Luria - Soviet neuropsychologist

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Long-term Memory• Shereshevskii suffered from synaesthesia• stimulation of one sense leads to automatic stimulation

of another • hearing a sound produces a visual experience

“I can see the music…”

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Long-term Memory• random number table

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Long-term Memory

1 this is a proud, well-built man 2 is a high-spirited woman 3 is a gloomy person6 is a man with a swollen foot7 is a man with a moustache 8 is a very stout woman - a sack within a sack.

“As for the number 87, what I see is a fat woman and a man twirling his moustache”

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Long-term Memory• memory consists of associative networks• perhaps mnemonists can create better networks

To Kill A Mockingbird

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Long-term Memory• memory consists of associative networks• perhaps mnemonists can create better networks

To Kill A Mockingbird

highschoolMr. Lacey

English

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Long-term Memory• memory consists of associative networks• perhaps mnemonists can create better networks

birdcanary

chicken

mockingbird

To Kill A Mockingbird

racism

highschool

Martin Luther King

skiing

Mr. Lacey

English

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• What do you think the brain of someone that has this “super memory” would look like?

Long-term Memory

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• What if I told you it looked like this?

Long-term Memory

Kim Peek

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Long-term Memory• macroencephaly• no corpus callosum• no anterior/posterior commisure

• degenerated cerebellum

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• Autism?• Motor disturbances• Overall I.Q. of 87

• despite this, he displays some amazing abilities…

Long-term Memory

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Long-term Memory

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Long-term Memory

http://www.youtube.com/watch?v=k2T45r5G3kA

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Long-term Memory• 98% retention rate for reading material• reads on average 8 books a day (has approximately 9000

memorized!)• one page every 8-10 seconds• also has incredible memory for music, often remembering

compositions only experienced once

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Long-term MemoryWhat could support this ability?

“Does brain damage stimulate compensatorydevelopment in some other area of the brain, or does it

simply allow otherwise latent abilities to emerge?”

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Long-term Memory