Hepatic Injury Secondary to Renal Ischemia-Reperfusion (I/R) Injury:
Ischemia/Reperfusion: Effect of nor-NOHA on Mycordial Injury
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Transcript of Ischemia/Reperfusion: Effect of nor-NOHA on Mycordial Injury
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Data demonstrating reduction of myocardial infarct size in most
characterized small animal preclinical model
nor-NOHA
- selective arginase inhibitor, affects nitric oxide pathway
- rats administered vehicle or nor-NOHA at 15 minutes prior to
induction of myocardial ischemia
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Effect of nor-NOHA on MyocardialIschemia / Reperfusion Injury in the Rat
Ischemic Zone / Area at Risk (%)
Vehicle (n=7)
nor-NOHA 100mg/kg (n=6)