ipsogen product line - QIAGEN

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ipsogen ® product line Sample to Insight The ipsogen product line provides a wide range of qualitative and quantitative oncohematology biomarker assays designed in compliance with the most recent international standards. QIAGEN ® ‘s ipsogen assays give you precise, accurate and reproducible results, and are easy to use with the Rotor-Gene ® Q real-time PCR system.

Transcript of ipsogen product line - QIAGEN

Page 1: ipsogen product line - QIAGEN

ipsogen® product line

Sample to Insight

The ipsogen product line provides a wide range of qualitative and quantitative oncohematology biomarker assays designed in compliance with the most recent international standards.

QIAGEN®‘s ipsogen assays give you precise, accurate and reproducible results, and are easy to use with the Rotor-Gene® Q real-time PCR system.

Page 2: ipsogen product line - QIAGEN

Product Description Cat. no.

JAK2JAK2 RGQ PCR Kit (24) Quantitative assay for 24 reactions: V617F Positive Control, V617F

Negative Control, 2 sets of standards plasmid dilutions JAK2 wild-type and JAK2 V617F, qPCR master-mix, 2 Primers and Probe Mixes JAK2 wild-type and JAK2 V617F including internal control

673613

ipsogen JAK2 V617F MutaQuant® Kit (24)

Quantitative assay for 24 reactions: V617F Positive Control, V617F Negative Control, 2 sets of standards plasmid dilutions JAK2 wild-type and JAK2 V617F, 2 Primers and Probe Mixes JAK2 wild-type and JAK2 V617F

673513

ipsogen JAK2 V617F MutaSearch® Kit (24)

Qualitative assay for 24 reactions: V617F Positive Control, V617F Negative Control, V617F Cut-Off Sample (1%), 2 Primers and Probe Mixes JAK2 wild-type and JAK2 V617F

673813

CALRCALR RGQ PCR Kit (24) For 24 reactions: Wild-type CALR Control, Mutant CALR Control,

CALR TYPE1 Reaction Mix, CALR TYPE2 Reaction Mix, CALR CLAMP1 Reaction Mix, CALR CLAMP2 Reaction Mix, CALR CLAMP3 Reaction Mix, CALR CLAMP4 Reaction Mix, CALR CLAMP5 Reaction Mix, Taq DNA polymerase, TE buffer for dilution and NTC

674013

MPL W515 L/K Mutationsipsogen MPL W515L/K MutaScreen Kit (24)

Qualitative assay for 24 reactions: MPL L/K Positive Controls, MPL L/K Negative Control, MPL L/K Cut-Off Sample (1.5%), 2 Primers and Probe Mixes MPL wild-type and MPL mutant

676413

Product Description Translocation Cat. no.

BCR-ABL1 MbcrBCR-ABL1 Mbcr RGQ RT-PCR Kit (24) Complete quantitative assay for 24 reactions: Reverse

transcriptase, RT Mix, High Positive RNA Control, Low Positive RNA Control, IS-MMR Calibrator, Mbcr and ABL1 Single Plasmid Standards, Taq DNA polymerase, BCR-ABL1 Mbcr and ABL1 qPCR Master mix

t(9;22), p210 chimeric

protein

670913

ipsogen BCR-ABL1 Mbcr IS-MMR DX Kit (24)

Complete quantitative assay for 24 reactions: Reverse transcriptase, 5x RT buffer, dNTP mix, Random primers, RNase Inhibitor, DTT, High Positive RNA Control, IS-MMR Calibrator, Mbcr and ABL Single Plasmid Standards, Primers and Probe Mix ABL, Primers and Probe Mix BCR-ABL Mbcr

t(9;22), p210 chimeric

protein

670813

ipsogen BCR-ABL1 Mbcr IS-MMR Kit (24)

Quantitative assay for 24 reactions: High Positive RNA Control, IS-MMR Calibrator, Mbcr and ABL Single Plasmid Standards, Primers and Probe Mix ABL, Primers and Probe Mix BCR-ABL1 Mbcr Fusion Gene

t(9;22), p210 chimeric

protein

670713

ipsogen BCR-ABL1 Mbcr Control Kit Cell lines with negative, high, and low positive expression of the BCR-ABL1 Mbcr fusion gene

t(9;22), p210 chimeric

protein

670191

Page 3: ipsogen product line - QIAGEN

Product Description Cat. no.

WT1ipsogen WT1 ProfileQuant® Kit (24) Quantitative assay for 24 reactions: ABL Control Gene Standards, WT1 (exon1-2)

Gene Standards, Primers and Probe Mix ABL, Primers and Probe Mix WT1676913

BAALCipsogen BAALC ProfileQuant Kit (24) Quantitative assay for 24 reactions: ABL Control Gene Standards, BAALC

Standards, Primers and Probe Mix ABL, Primers and Probe Mix BAALC676613

NPM1 Mutations A, B and Dipsogen NPM1 MutaScreen Kit (24) Qualitative assay for 24 reactions: Wild-type NPM1 Control, Mutated NPM1

Control, Primers and Probe Mix PPM-Total NPM1, Primers and Probe Mix PPM-Mutated NPM1, Primers and Probe Mix PPM-NPM1 MutA, Primers and Probe Mix PPM-NPM1 MutB, Primers and Probe Mix PPM-NPM1 MutD

677013

ipsogen NPM1 mut A MutaQuant Kit (24)

Quantitative assay for 24 reactions: ABL Control Gene Standards, NPM1 MutA Gene Standards, Primers and Probe Mix ABL, Primers and Probe Mix NPM1 mutA Mutated Gene

677513

ipsogen NPM1 mut B&D MutaQuant Kit (24)

For 24 reactions: ABL Control Gene Standards, NPM1 MutB Gene Standards, NPM1 MutD Gene Standards, Primers and Probe Mix ABL, Primers and Probe Mix NPM1 mutB Mutated Gene, Primers and Probe Mix NPM1 mutD Mutated Gene

677613

Product Description Translocation Cat. no.

BCR-ABL1 mbcripsogen BCR-ABL1 mbcr Kit (24) ABL Control Gene Standards, BCR-ABL mbcr Fusion

Gene Standards, Primers and Probe Mix ABL, Primers and Probe Mix BCR-ABL mbcr Fusion Gene

t(9;22), p190 chimeric protein

670013

ipsogen BCR-ABL1 mbcr Controls Kit Cell lines with negative, high, and low positive expression

t(9;22), p190 chimeric protein

670091

PML-RARa bcr1, bcr2, bcr3ipsogen PML-RARA bcr1 Kit (24) Quantitative assay for 24 reactions: ABL Control

Gene Standards, PML-RARA bcr1 Fusion Gene Standards, Primers and Probe Mix ABL, Primers and Probe Mix PML-RARA bcr1 Fusion Gene

t(15;17)(q22;q21) PML-RARA long (L or bcr1)

672113

ipsogen PML-RARA bcr2 Kit (24) Quantitative assay for 24 reactions: ABL Control Gene Standards, PML-RARA bcr2 Fusion Gene Standards, Primers and Probe Mix ABL, Primers and Probe Mix PML-RARA bcr2 Fusion Gene

t(15;17)(q22;q21) PML-RARA variant

(V or bcr2)

672213

ipsogen PML-RARA bcr3 Kit (24) Quantitative assay for 24 reactions: ABL Control Gene Standards, PML-RARA bcr3 Fusion Gene Standards, Primers and Probe Mix ABL, Primers and Probe Mix PML-RARA bcr3 Fusion Gene

t(15;17)(q22;q21) PML-RARA short (S or bcr3)

672313

ipsogen PML-RARA bcr1 Controls Kit Cell lines with negative, high, and low positive expression of the PML-RARA bcr1 fusion gene

t(15;17)(q22;q21) PML-RARA long (L or bcr1)

672091

Page 4: ipsogen product line - QIAGEN

Product Description Cat. no.

Associated productsipsogen RT Kit (33) For 33 reactions: Reverse transcriptase, 5x RT buffer, dNTP mix, Random

primers, RNase Inhibitor, DTT679913

Rotor-Gene Q 5plex HRM System Real-time PCR cycler and High Resolution Melt analyzer with 5 channels (green, yellow, orange, red, crimson) plus HRM channel, laptop computer, software, accessories, 1-year warranty on parts and labor, installation and training

9001650

RNeasy® Mini Kit (50) For 50 RNA preps: 50 RNeasy Mini Spin Columns, Collection Tubes (1.5 ml and 2 ml), RNase-free Reagents and Buffers

74104

QIAamp® DNA Blood Maxi Kit (50) For 50 DNA maxipreps: 50 QIAamp Maxi Spin Columns, QIAGEN Protease, Buffers, Collection Tubes (50 ml)

51194

Product Description Translocation Cat. no.

RUNX1-RUNX1T1 and CBFB-MYH11ipsogen RUNX1-RUNX1T1 Kit (24) Quantitative assay for 24 reactions: ABL Control Gene

Standards, RUNX1-RUNX1T1 Fusion Gene Standards, Primers and Probe Mix ABL, Primers and Probe Mix RUNX1-RUNX1T1 Fusion Gene

t(8;21) 675013

ipsogen CBFB-MYH11 A Kit (24) Quantitative assay for 24 reactions: ABL Control Gene Standards, CBFB-MYH11 A Fusion Gene Standards, Primers and Probe Mix ABL, Primers and Probe Mix CBFB-MYH11 A Fusion Gene

inv(16) 676013

ETV6-RUNX1ipsogen ETV6-RUNX1 Kit (24) Quantitative assay for 24 reactions: ABL Control Gene

Standards, ETV6-RUNX1 Fusion Gene Standards, Primers and Probe Mix ABL, Primers and Probe Mix ETV6-RUNX1 Fusion Gene

t(12;21) 675113

Page 5: ipsogen product line - QIAGEN

Control Gene StandardsEach Control Gene Standard contains precisely controlled dilutions of a given gene.

Product Cat. no.

ipsogen ABL Control Gene 3 Standards 674691

ipsogen ABL Control Gene 4 Standards 674791

ipsogen B2M Control Gene Standards 674191

ipsogen GUS Control Gene Standards 674591

ipsogen BCR Control Gene Standards 674491

Fusion Gene StandardsEach Fusion Gene Standard contains precisely controlled dilutions of a given fusion gene.

Standard dilutions: 101, 102, 103, 105, 106 copies in 5 µl.

Product Target Cat. no.

ipsogen RARA-PML bcr1&2 Standards t(15;17) 672591

ipsogen RARA-PML bcr3 Standards t(15;17) 672691

ipsogen RUNX1-RUNX1T1 Standards t(8;21) 675091

ipsogen CBFB-MYH11 A Standards Inv(16) 676091

ipsogen CBFB-MYH11 D Standards Inv(16) 676191

ipsogen CBFB-MYH11 E Standards Inv(16) 676291

ipsogen PML-RARA bcr1 Standards t(15;17) 672191

ipsogen PML-RARA bcr2 Standards t(15;17) 672291

ipsogen PML-RARA bcr3 Standards t(15;17) 672391

ipsogen TCF3-PBX1 Standards t(1;19) 674891

ipsogen BCR-ABL1 mbcr Standards t(9;22) 670291

ipsogen BCR-ABL1 Mbcr Standards t(9;22) 670391

ipsogen ETV6-RUNX1 Standards t(12;21) 675191

ipsogen SIL-TAL1 Standards del (1p) 674991

ipsogen MLL-AF4 e10e4 Standards t(4;11) 678191

ipsogen MLL-AF4 e9e5 Standards t(4;11) 678391

ipsogen MLL-AF4 e11e5 Standards t(4;11) 678291

ipsogen MLL-AF9 type A e10e6 Standards t(9;11) 678691

ipsogen MLL-AF9 type B e8e9 Standards t(9;11) 678791

ipsogen MLL-AF6 e8e2 Standards t(6;11) 678491

ipsogen MLL-DUP e2e8 Standards dup11 678891

ipsogen MLL-ENL e9e2 Standards t(11;19) 679191

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MutaQuant StandardsEach MutaQuant Standard comprises 5 vials containing precisely controlled dilutions of a given mutant gene. Standard

dilutions: 101, 102, 103, 105, 106 copies in 5 µl.

Product Cat. no.

ipsogen NPM1 mut A cDNA MutaQuant Stds 677591

ipsogen NPM1 mut B&D cDNA MutaQuant Stds 677791

Fusion Gene Standards (continued)

Product Target Cat. no.

ipsogen MLL-ENL e10e2 Standards t(11;19) 679091

ipsogen MLL-AF9 e8e10 Standards t(9;11) 678591

ipsogen MLL-ELL e9e2 Standards t(11;19) 679391

ipsogen MLL-ELL e8e2 Standards t(11;19) 679291

ipsogen MLL-AF1p e10e2 Standards t(1;11) 678091

For more information, visit www.qiagen.com/Oncohematology-US

All these products are intended for research use only. Not for use in diagnostic procedures. No claim or representation is

intended to provide information for the diagnosis, prevention, or treatment of a disease.

For up-to-date licensing information and product-specific disclaimers, see the respective QIAGEN kit handbook or user

manual. QIAGEN kit handbooks and user manuals are available at www.qiagen.com or can be requested from QIAGEN

Technical Services or your local distributor.

Trademarks: QIAGEN®, Sample to Insight®, QIAamp®, ipsogen®, MutaQuant ®, MutaSearch®, ProfileQuant ®, RNeasy®, Rotor-Gene® (QIAGEN Group).© 2020 QIAGEN, all rights reserved. PROM-6444-006

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