Iontophoresis - FysioSupplies...chAttAnooGA ionto FeAtures The dual channel Chattanooga Ionto device...

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I o n t o p h o r e s i s 2012

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ASIA-PACIFIC:DJO Asia-Pacific LimitedUnit 1905, 19/F, Tower IIGrand Central Plaza138 Shatin Rural Committee RoadShatinHONG KONGTel: +852 3105 2237Fax: +852 3105 1444Email: [email protected]

EUROPE, MIDDLE EAST & AFRICA DJO BeneluxWelvaartstraat 82200 HerentalsBELGIUMTel: +32 (0) 14248350Fax: +32 (0) 14248358Email: [email protected]

LATIN AMERICA:DJO Global, Inc1430 Decision StreetVistaCA 92081-8553U.S.A.Tel: 1 800 336 6569Fax: 1 800 936 6569Email: [email protected]

AUSTRALIA:DJO AustraliaPO Box 2057NormanhurstNSW 2076AUSTRALIATel: +1300 66 77 30Fax: +1300 66 77 40Email: [email protected]

BENELUX:DJO BeneluxWelvaartstraat 82200 HerentalsBELGIUMTel Belgium: 0800 18 246Tel Netherlands: 0800 0229442Tel Luxemburg: 8002 27 42Email: [email protected]

DENMARK, FINLAND,NORWAY & SWEDEN:DJO Nordic ABMurmansgatan 12621225 MalmöSWEDENTel Sweden: 040 39 40 00Tel Norway: 8006 1052Tel Finland: 0800 114 582Tel Denmark: +46 40 39 40 00Email: [email protected]

FRANCE:DJO France S.A.S.Centre Européen de Fret64990 MouguerreFRANCETel: +33 (0)5 59 52 86 90Fax: +33 (0)5 59 52 86 91Email: [email protected]

GERMANY:ORMED-DJO Germany GmbHMerzhauser Str. 112D-79100 FreiburgGERMANYTel: +49 761 4566 251Fax: +49 761 4566 55251Email: [email protected]

ITALY:DJO Italia SrlVia Leonardo Da Vinci 97Trezzano Sul Naviglio20090 MilanoITALYTel: +39 02 484 63386Fax: +39 02 484 09217Email: [email protected]

SWITZERLAND:Compex Médical SACh. du DéventZI Larges Pièces A1024EcublensSWITZERLANDTel: +41 (0) 21 695 2360Fax: +41 (0) 21 695 2361Email: [email protected]

UK & IRELAND:DJO UK Ltd1a Guildford Business ParkGuildfordSurreyGU2 8XGENGLANDTel: +44 (0)1483 459 659Fax: +44 (0)1483 459 470Email: [email protected]

UNITED STATES:DJO Global, Inc1430 Decision StreetVistaCA 92081-8553U.S.A.Tel: 1 800 336 6569Fax: 1 800 936 6569

CANADA:DJO Canada6485 Kennedy RoadMississaugaOntarioL5T 2W4CANADATel: +1 1866 866 5031Fax: +1 1866 866 5032Email: [email protected]

DJO GLOBAL:

DJO GLOBAL, EXPORT CENTERS:

SPAIN:DJO IbéricaCarretera de Cornellá 144, 1º 4ªEsplugues de Llobregat08950 BarcelonaSPAINTel: +34 943 638 167Fax: +34 943 638 174Email: [email protected]

1 Iontophoresis

introduction

iontophoresis

Iontophoresis is an active transdermal drug delivery system that delivers drug ions through the skin

using a low level electric current.

Direct Current is used to move a drug or therapeutically active ion through the skin. When direct

current (DC) is applied to an ionized drug solution, the ions that have the same charge as the current

are repelled by the current and are delivered through the skin. The aim is to drive active ions locally

rather than having to inject them or have them taken systemically.

Chattanooga is the world’s largest manufacturer of rehabilitation equipment for treating musculoskeletal, neurological and soft tissue disorders. For over

six decades, Chattanooga has set a benchmark for leadership, reliability and excellence. Our products contribute to better treatment outcomes in hospitals,

clinics and home settings worldwide. We lead the physiotherapy industry by example and, through continuous innovation, provide real world solutions for

clinicians and their patients.

As the world’s leading brand in rehabilitation, Chattanooga is sold in over 80 countries worldwide. Chattanooga is directly represented in our key markets but

also has long lasting relationships with dedicated distributors in the USA, Canada, Latin America, EMEA and Asia Pacific. Our Chattanooga distributors and

customers are supported for order placement, training, product delivery and after sales service by a dedicated team of highly skilled DJO employees based all

over the world.

Chattanooga is a brand of DJO Global Inc. DJO Global provides solutions for musculoskeletal health, vascular health and pain management. Our products help

prevent injuries or rehabilitate after surgery, injury or from degenerative disease, enabling patients to regain or maintain their natural motion.

Visit www.DJOglobal.eu

Tissue Concentrations10-2

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10-200ng

2-4mg

56µg

Oral1 Phoresor®2 Injection3

Route of Administration

References: 1. Glass, J.M., et al. 1980 Int. J dermatol 19:519-525.2. Petelenz, T.J. 1992. Controlled Release. 20:55-66.3. Dosis recomendadas

(PDR).

Active electrode

Skin surface

Epidermis

Dermis

Blood vessel

Iontophoresis Drug Delivery

TM

2www.DJOglobal.eu

indications:

iontophoresis is used to administer water-soluble ionic medications to:

• Treat Acute Tendonitis

• Treat Pain Associated with Calcific Deposits

• Provide Dermal Anesthesia

Tissue Concentrations10-2

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10-4

10-5

10-6

10-7

10-8

Log

Conc

entr

atio

n / G

ram

of T

issu

e

Ther

aput

ic R

ange

10-200ng

2-4mg

56µg

Oral1 Phoresor®2 Injection3

Route of Administration

References: 1. Glass, J.M., et al. 1980 Int. J dermatol 19:519-525.2. Petelenz, T.J. 1992. Controlled Release. 20:55-66.3. Dosis recomendadas

(PDR).

Active electrode

Skin surface

Epidermis

Dermis

Blood vessel

Alternatives to iontophoresis are injections, oral medications and passive transdermal medications.Benefits of iontophoresis over the alternatives:

compared to injections:

• Virtually painless

• Non-invasive minimizing:

- Risk of infection

- Risk of tissue necrosis, tendon rupture, etc.

compared to oral medications:

• Localized drug delivery, non-systemic

• Avoid risk of systemic side effects

contraindications:

• Damaged or denuded skin

- Recent scar tissue

• Drug allergies

• Trans-cranial

• Orbital region

• Electrically sensitive support systems

- Pacemaker

considerations:

• Diabetes

• Pregnancy

• Over external metal fixation devices

• “Elderly” skin

3 Iontophoresis

orderinG inForMAtion

Part Number Description

Chattanooga Ionto

1335Chattanooga Ionto Dose Controller (Includes lead wire, batteries, case, instruction guide and warranty card)

13214Replacement Leadwire (Use Chattanooga Ionto Dose Controller)

1336 Black Snap Adapters, (Pack of 2)

5020014

Twin Lead Assembly for Phoresor II Auto Dose Controller (Use only with PM850/PM900 and Iogel, TransQ Flex, TransQ E, and Optima electrodes)

chAttAnooGA ionto™

FeAtures

The dual channel Chattanooga Ionto device delivers a constant direct current no matter the resistance level. By

varying the voltage output as resistance changes, the device consistently delivers the programmed dose.

The device’s pause feature lets you check the treatment area without restarting the session. Chattanooga Ionto

gives you the user-friendly features and reliability you expect.

• 2-channels to treat 2 sites or deliver 2 medications simultaneously

• Previous dosage can be set as default to maintain frequently used treatment parameters

• Beeping alerts if electrode fault for open current or high impedance, low battery, treatment completion or

power left on

• Automatic 30 second current ramp up and down during power on/off keeps patient comfortable

• Constant current provides precise, accurate delivery regardless of skin impedance

• Current can be set in 0.1 mA increments between 0.5 mA and 4 mA

technicAL speciFicAtions

Output Specs: ±15% unless noted

Current Range:0.5 - 4mA ±10% at 100 to 12k ohm load

Dose Range: 0 to 160mA/minute

Dose Accuracy: ±2mA minute

Ramp Up/Ramp Down: 30 seconds

Battery: 9V Alkaline

Dimensions: 2 x 6 x 9 cm (L x W x H)

Weight: 77g

Safety Tests: EN60601-1-2

4www.DJOglobal.eu

coMpAnion 80™ orderinG inForMAtion


Companion 80

5000044Companion 80 Iontophoresis System = 1.1 cc fill, (6 treatment kits per box)

* In vitro test data on file at IOMED, Inc.

** 5000 Ohm load simulates skin resistance

FeAtures

Designed to deliver an 80 mA-minute dose over 24 hours, allowing the patient to tend to normal daily

activities while receiving treatment.

Battery-powered

• Internal 1 volt battery - no wires to connect

• Reserve battery capacity compensates for patients

with higher skin resistance

hypoallergenic Adhesive

• Adheres well, even in the shower

• Conforms well to treatment areas

• Fits comfortably beneath clothing

silver-silver chloride ph stabilizing

• Conducts more efficiently than Carbon

• Stabilizes pH without using chemical buffers

reF 5000044 - companion 80

reFerences

1. Banta CA. A prospective, nonrandomized study of iontophoresis, wrist splinting, and anti-inflammatory medication in the treatment of early-mild carpal tunnel syndrome. J Occup Med 36: 166-168, 1994.2. Bertolucci LE. Introduction of anti-inflammatory drugs by iontophoresis: Double blind placebo controlled study. J Orphop Sports Phys Ther 4: 103-108, 1982.3. Glass JM, et al. The quality and distribution of radiolabeled dexamethasone delivered to tissue by iontophoresis. Int J Dermatol 19: 519-525, 1980.4. Gudeman SD, et al. Treatment of plantar fasciitis by iontophoresis of 0.4% dexamethasone: A randomized, double-blind placebo-controlled study. Am J Sports Med 25: 312-316, 1997.5. Nirschl, RP, et al. Iontophoretic administration of dexamethasone sodium phosphate for acute epicondylitis: A randomized, double-blind, placebo controlled study. Am J Sports Med 31: 189-195, 2003.6. Pellecchia, GL, et al. Treatment of infrapatellar tendonitis: A combination of modalities and transverse friction massage versus iontophoresis. J Sports Rehabil 3: 135-145, 1994.7. Petelenz TJ, et al. Ionotophoresis of dexamethasone: Laboratory studies. J Controlled Release 20: 55-66, 1992.

These products are protected by one or more of the following U.S. Patents: 4,744,787; 4,752,285; 5,135,477; 5,374,241; 5,415,628; 5,558,632; 5,846,217; 6,731,977. Other Patents Pending.

5 Iontophoresis

trAnsQ®

optiMA™



TransQ

5000008TransQ E, Medium (Disposable electrodes, 2.5 cc - 3.0 cc fill, 12 kits* per box)

5000009TransQ E, Small (Disposable electrodes, 1.5 cc - 2.0 cc fill, 12 kits* per box)

5000033TransQ Flex (Disposable electrodes, 2.5 cc fill, 12 kits* per box)

* Kits above include one each: drug delivery electrode, disposable dispersive pad, and alcohol wipe

FeAtures

silver-silver chloride ph stabilizing electrodes

IOMED’s proprietary Silver-Silver Chloride conductive element prevents water hydrolysis, thereby eliminating

the need to add a chemical buffer and minimizing skin irritation.

Designed in a variety of Shapes for Treating many different areas of the body.

transQ e

• Rectangular and circular shapes for various

treatment sites

• Adhesive Foam

• Stretches and adheres well under stress

transQ Flex

• Clover Shape

• Surrounds highly contoured treatment area

• Perfect for fingers, hands, feet and ankles

• Superior Adhesion

• Adds more surface area to increase adhesion when

under stress

• Patented Hydrogel

- Provides uniform current distribution

- Consistent drug delivery

reF 5000009 - transQe small reF 5000008 - transQe Medium reF 5000033 - transQ Flex



Optima

5000050Optima, Small (Disposable electrodes, 1.5 cc fill, 12 kits* per box)

5000051Optima, Medium (Disposable electrodes, 2.0 cc fill, 12 kits* per box)

5000052Optima, Large (Disposable electrodes, 3.0 cc fill, 12 kits* per box)


FeAtures

ph Buffered iontophoresis electrodes

Adjusts the pH to the ideal target of 4.5 to optimize transport when using a carbon conductive element and

maintains that ideal pH for better drug delivery.

ph defining Agent

• Adjusts pH to ideal target to optimize transport

when using a carbon conductive element

ph Buffering Agent

• Maintains ideal pH

Viscosity enhancing element

• Creates uniform current distribution for greater

patient comfort

• Conforms to a wide variety of treatment sites

• Stretches and adheres well when under stress

reF 5000050 - optima small reF 5000051 - optima Medium reF 5000052 - optima Large

6www.DJOglobal.eu

ioGeL®

elliptical shape

• Follows the line of the tendon

clear Adhesive

• Allows precise placement on target site

Gelsponge®

• Ensures complete contact between the electrode

and the skin surface with low impedance

• Provides a conductive medium similar to ultrasound gel

eZ Fill Window™

• Protects adhesive during hydration and handling

• Provides no-stick handling

reF 5000021 - iogel small reF 5000022 - iogel Medium reF 5000023 - iogel Large



Iogel

5000021Iogel, Small (Disposable electrodes, 1.5 cc fill, 12 kits* per box)

5000022Iogel, Medium (Disposable electrodes, 2.5 cc fill, 12 kits* per box)

5000023Iogel, Large (Disposable electrodes, 3.55 cc fill, 12 kits* per box)


FeAtures

silver-silver chloride ph stabilizing electrodes

Iogel, a market-leading electrode with features that allow for precise placement, pH stabilization, superior

patient comfort and ease of filling.

dupeL B.L.u.e.

dupeL White

• High efficiency, bi-layer design for optimal drug delivery

• Patented ion-exchange buffering system ensures that pH shifts occurring during iontophoresis are controlled

• Four shapes/sizes for best adhesion, conformability and coverage

• Latex Free

FeAtures

ph Balancing electrode

Patented buffer adjusts medication pH to a safe level (4-8 pH) without introducing competing ions that

decrease medication delivery. This allows maximum flexibility and safety when selecting a medication.

• Capable of delivering 80 mAmin

• Cost-Effective

• Available in various sizes

• Latex Free

FeAtures

The Dupel White Electrodes are a cost effective option in iontophoretic drug delivery. Using a patented design,

the active electrode employs a unique buffering system that enhancing efficiency and comfort.



Dupel B.L.U.E.

199332-001Dupel B.L.U.E., Small (Disposable electrodes, 1.5 cc fill, 12 kits* per box)

199334-001Dupel B.L.U.E., Butterfly (Disposable electrodes, 2.0 cc fill, 12 kits* per box)

199335-001 Dupel B.L.U.E., Standard (Disposable electrodes, 2.5 cc fill, 12 kits* per box)

199336-001Dupel B.L.U.E., Large (Disposable electrodes, 4.0 cc fill, 12 kits* per box)



Dupel White

198808-001Dupel White, Small (Disposable electrodes, 2.0 cc fill, 12 kits* per box)

198572-001Dupel White, Butterfly (Disposable electrodes, 2.5 cc fill, 12 kits* per box)

198809-001 Dupel White, Standard (Disposable electrodes, 2.5 cc fill, 12 kits* per box)

198810-001Dupel White, Large (Disposable electrodes, 4.0 cc fill, 12 kits* per box)

reF 199332 - small reF 199334 - Butterfly reF 199336 - LargereF 199335 - standard

reF 198808 - small reF 198572 - Butterfly reF 198810 - LargereF 198809 - standard

Iontophoresis - FysioSupplies...chAttAnooGA ionto FeAtures The dual channel Chattanooga Ionto device...

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