Intuitive Surgical, Inc.

Ticker: ISRG

April 22, 2008

The Company

Intuitive Surgical is the global technology leader in the rapidly emerging field of robotic-assisted minimally invasive surgery (MIS). The Company's da Vinci® Surgical System offers surgeons superior visualization, enhanced dexterity, greater precision and ergonomic comfort for the optimal performance of MIS. The da Vinci System enables surgeons to perform even complex procedures, such as open-heart surgery, through 1-2 cm incisions.

History 1995 – Intuitive Surgical was founded Surgical robotics was little more than a medical

curiosity until the 1999 introduction of the da Vinci® Surgical System

2000 – da Vinci became first robotic surgical system cleared by FDA for general laparoscopic surgery

June 2000 – Successful ISRG IPO 2003 – Intuitive Surgical acquired its principal

competitor Computer Motion, strengthening its intellectual property holdings and ensuring its position as the world’s sole provider of robotic-assisted surgical systems

Now 795 da Vinci® System base as of 12/31/07

595 United States, 136 Europe, 64 Rest of World Exclusive rights to over 400 U.S. and foreign patents Relationships with industry leaders including IBM

Corporation, Massachusetts Institute of Technology, and Heartport, Inc. (Johnson & Johnson)

Industry collaborations with companies including Ethicon Endo-Surgery (Johnson & Johnson), Medtronic, and Olympus Optical

FDA clearances for laparoscopic, thoracoscopic, prostatectomy, cardiotomy, revascularization, urology, gynecology, and pediatric procedures da Vinci Prostatectomy procedure is currently the fastest-

growing treatment for prostate cancer (the second leading cause of cancer-related death in men)

Revenue Model

Source: Intuitive Surgical IR Presentation

“Taking surgical precision and technique beyond the limits of the human hand” ™

Source: Intuitive Surgical Corporate Overview Brochure

Hospital Benefits Market Share Growth

Increased patient satisfaction New patients and increased referrals Recruitment and retention of top surgical talent Enhanced hospital reputation

Maximizing Efficiencies Decreased length of stay Decreased complications Decreased blood transfusions Decreased nursing staff ratios Decreased post-operation pain management

Broad Utilization Mix Application across multiple surgical specialties

Cardiac“In MVST (Multi-Vessel Small Thoracotomy) our patients avoid sternotomy, CPB and aortic manipulation. As a result they benefit from reduced morbidity, shortened hospital stay, faster recovery and improvement of postoperative quality of life.”- Michael Argenziano, M.D.Assistant Professor of SurgeryColumbia University College of Physicians and Surgeons, New York Presbyterian Hospital

“The da Vinci® System makes it possible to offer a wider range of patients a minimally invasive open-heart procedure to repair the mitral valve. This will allow more patients to benefit from both shorter hospital stays and reduced recovery times.”- W. Randolph Chitwood, Jr. M.D.Professor and Chairman Department of SurgeryChief of Cardiothoracic SurgeryEast Carolina University School of Medicine

Source: Intuitive Surgical Corporate Overview Brochure

Urology“As a trained surgical oncologist, da Vinci® has allowed me to offer my patients a better cancer operation with improved clinical outcomes.”- Thomas E. Ahlering, M.D.

Associate Professor of Urology

Director, Urological Oncology

University of California Irvine Medical Center

“In my experience, robotics allows for greater surgical precision which leads to improvements in cancer control, potency, and urinary function.”- Mani Menon, M.D.

Director, Vattikuti Urology Institute

Henry Ford Health System

Source: Intuitive Surgical Corporate Overview Brochure

General Surgery“I can achieve superb clinical results in technically demanding operations such as Heller myotomy and Esophagectomy with fewer complications.”- Santiago Horgan, M.D.

Director of Minimally Invasive Surgery

University of Illinois, Chicago

Source: Intuitive Surgical Corporate Overview Brochure

Source: Intuitive Surgical IR Presentation

Source: Intuitive Surgical IR Presentation

IncomeStatement($M) Gross Margin 69.0% 66.5% 67.6% 63.4% 48.0%

Operating Margin 34.4% 28.8% 30.2% 15.3% (13.0%)

Net Margin 24.1% 19.3% 41.4% 16.9% (10.5%)

Source: Yahoo! Finance

Balance Sheet($M)

Source: Yahoo! Finance

Statement of Cash Flows($M)

Source: Yahoo! Finance

FCF/Revenue 30.2% 21.8% 17.5% 5.7% (14.2%)

Growth Potential Over 6000 hospitals in the U.S. alone; Intuitive

has only tapped about 795 worldwide Intuitive Surgical estimates 55% total procedure

growth in 2008 Intuitive Surgical estimates 40% dVP procedure

growth ACS estimates 186,295 new cases of prostate cancer in

2008

Intuitive Surgical estimates 150% dVH procedure growth

Over 600,000 women undergo hysterectomies every year

Reference

Intuitive Surgical, Inc. website (www.intuitivesurgical.com)