INTRODUCTION( 介 绍 )

Xi ZhangShanghai Municipal Center

for Disease Control

Guideline( 目录 )

• Brief Introduction of SCDC （ SCDC 简介）

• Introduction of Lab of Microbiology

（微生物实验室 简介）• Brief Introduction of Myself （个人介绍）

Sight Seeing of SCDC(SCDC 业务大楼 )

New Lab Buiding(SCDC 实验大楼 )

Goals of SCDC( 目 标 )

Established Public SystemEstablished Public Systemmeet health needsmeet health needs improve quality of citizen lifeimprove quality of citizen lifeensure the persistent social and economic ensure the persistent social and economic

development of the city.development of the city.

Goals and Objectives of SCDC( 目 标 )

To expand responsibility on public health to meet social To expand responsibility on public health to meet social and individual needsand individual needs

To improve the ability of rapid response to the urgent events and disasters;

To offer high quality health services for community; To improve the preventive medicine research level To promote national and international collaboration

MISSION of SCDC ( 任 务 )

Policy making and planning Surveillance and information synthesis Implementation of prevention and intervention Public health research Prevention and health care service

Dept of Chronic Dept of Chronic Diseases PreventionDiseases Prevention

Dept of Chronic Dept of Chronic Diseases PreventionDiseases Prevention

Dept ofDept of Health Care for Health Care for

Children&AdolescentsChildren&Adolescents

Dept ofDept of Health Care for Health Care for

Children&AdolescentsChildren&Adolescents

Dept of Dept of NutritionNutritionDept of Dept of

NutritionNutrition

Division for Division for Chronic Diseases Chronic Diseases

PreventionPrevention

Division for Division for Chronic Diseases Chronic Diseases

PreventionPrevention

Dept of Epidemic Dept of Epidemic PreventionPrevention

Dept of Epidemic Dept of Epidemic PreventionPrevention

Dept of Immunization Dept of Immunization Vaccine ManagementVaccine Management

Dept of Immunization Dept of Immunization Vaccine ManagementVaccine Management

Dept of Vector Dept of Vector Control & Control & PreventionPrevention

Dept of Vector Dept of Vector Control & Control & PreventionPrevention

Dept of Parasitosis Dept of Parasitosis Control&Prevention Control&Prevention

Dept of Parasitosis Dept of Parasitosis Control&Prevention Control&Prevention

Dept of Tuberculosis Dept of Tuberculosis Control&PreventionControl&Prevention

Dept of Tuberculosis Dept of Tuberculosis Control&PreventionControl&Prevention

Dept of Dept of HIV/AIDS,STD HIV/AIDS,STD

Control & PreventionControl & Prevention

Dept of Dept of HIV/AIDS,STD HIV/AIDS,STD

Control & PreventionControl & Prevention

Dept of Dept of DisinfectionDisinfection

Dept of Dept of DisinfectionDisinfection

Lab of Lab of MicrobiologyMicrobiology

Lab of Lab of MicrobiologyMicrobiology

Division Division forfor communicablecommunicable

DiseaseDisease Control&PreventionControl&Prevention

Division Division forfor communicablecommunicable

DiseaseDisease Control&PreventionControl&Prevention

Dept of Dept of Occupational Occupational

HealthHealth

Dept of Dept of Occupational Occupational

HealthHealth

Dept of Dept of Environmental Health Environmental Health

ResearchResearch

Dept of Dept of Environmental Health Environmental Health

ResearchResearch

Lab of Lab of Molecular Molecular

Biology & GeneBiology & Gene

Lab of Lab of Molecular Molecular

Biology & GeneBiology & Gene

Division for Division for Environmental & Environmental &

Occupational HealthOccupational Health

Division for Division for Environmental & Environmental &

Occupational HealthOccupational Health

Dept of Dept of EnvironmentalEnvironmental

Health Evaluation Health Evaluation

Dept of Dept of EnvironmentalEnvironmental

Health Evaluation Health Evaluation

Dept of Dept of Toxicology Toxicology Dept of Dept of

Toxicology Toxicology

Lab ofLab ofChemicalAnalysisChemicalAnalysis

Lab ofLab ofChemicalAnalysisChemicalAnalysis

Dept of Food Dept of Food Health and SafetyHealth and Safety

Dept of Food Dept of Food Health and SafetyHealth and Safety

Lab of Lab of Experimental Experimental

AnimalAnimal

Lab of Lab of Experimental Experimental

AnimalAnimal

Division forDivision for Health & Safety Health & Safety

AssessmentAssessment

Division forDivision for Health & Safety Health & Safety

AssessmentAssessment

Office of Office of Preventive Health Preventive Health

ExaminationExamination

Office of Office of Preventive Health Preventive Health

ExaminationExamination

Office of Medical Office of Medical Examination for Examination for

DriversDrivers

Office of Medical Office of Medical Examination for Examination for

DriversDrivers

Dept of Dept of Occupational Occupational

Health Health ExaminationExamination

Dept of Dept of Occupational Occupational

Health Health ExaminationExamination

Division forDivision for Health Care Health Care

ServiceService

Division forDivision for Health Care Health Care

ServiceService

Dept of Dept of Health Health

StatisticsStatistics

Dept of Dept of Health Health

StatisticsStatistics

Central Central librarylibrary

Central Central librarylibrary

Dept of Dept of computer computer

administrationadministration

Dept of Dept of computer computer

administrationadministration

Division for Division for Health Health

InformationInformation

Division for Division for Health Health

InformationInformation

Personnel & Security officePersonnel & Security officePersonnel & Security officePersonnel & Security office

Logistics officeLogistics officeLogistics officeLogistics office Financing (Auditing) officeFinancing (Auditing) officeFinancing (Auditing) officeFinancing (Auditing) office

Assents Manage officeAssents Manage officeAssents Manage officeAssents Manage office

Capital Construction officeCapital Construction officeCapital Construction officeCapital Construction office

Quality control officeQuality control officeQuality control officeQuality control officeAssociation Manage officeAssociation Manage officeAssociation Manage officeAssociation Manage office

Test Manage officeTest Manage office Test Manage officeTest Manage office Research and Education Research and Education

officeoffice

Research and Education Research and Education

officeoffice

Editorial DepartmentEditorial DepartmentEditorial DepartmentEditorial DepartmentTraining Training DepartmentDepartmentTraining Training

DepartmentDepartment

Shanghai Municipal Center for Disease Shanghai Municipal Center for Disease Control and PreventionControl and Prevention

Shanghai Institute of Preventive Shanghai Institute of Preventive MedicineMedicine

Shanghai Municipal Center for Disease Shanghai Municipal Center for Disease Control and PreventionControl and Prevention

Shanghai Institute of Preventive Shanghai Institute of Preventive MedicineMedicine

Administration officeAdministration officeAdministration officeAdministration office

SCDC Organization Chart

SCDC RESOURCE

• Employee: More than 700 persons• Technical Employee: more than 530 persons• Lab area: 32,000m2

• Instrument capital: over 200 million Yuan (RMB)

上海市疾病预防控制中心上海市预防医学研究院

上海疾控安全健康保健评价中心

上海市疾病预防控制中心上海市预防医学研究院

上海疾控安全健康保健评价中心

检验管理科检验管理科 科技教育科科技教育科质量管理科

（生物安全领导小组办公室）质量管理科

（生物安全领导小组办公室）

中心（院）办公室中心（院）办公室

后勤管理科后勤管理科人事保卫科人事保卫科

生物安全领导小组生物安全领导小组

微

生

物

实

验

室

微

生

物

实

验

室

免疫规划实验室

免疫规划实验室

结核病防治实验室

结核病防治实验室

艾滋病性病麻风病

防治实验室

艾滋病性病麻风病

防治实验室

病媒生物防治实验室

病媒生物防治实验室

寄生虫病防治实验室

寄生虫病防治实验室

消

毒

实

验

室

消

毒

实

验

室

毒

理

室

毒

理

室

理化分析实验室

理化分析实验室

公共卫生分子生物学

研究室

公共卫生分子生物学

研究室

环境卫生实验室

环境卫生实验室

食品卫生与食源性

疾病防治实验室

食品卫生与食源性

疾病防治实验室

职业卫生与

中毒控制实验室

职业卫生与

中毒控制实验室

菌毒种与生物样品

保藏中心

菌毒种与生物样品

保藏中心

实验室供应中心

实验室供应中心

放射卫生实验室

放射卫生实验室

营养卫生实验室

营养卫生实验室

健康相关产品卫生评价实验

室

健康相关产品卫生评价实验

室

环境职业场所卫生评价实验

室

环境职业场所卫生评价实验

室

LAB MAMAGEMENT ORGANIZITION CHART

SCDC Lab Management Accredited with ISO /IEC17025:1999 certification Accredited with Metrology Certification Pay more attention to lab safety and bio-safety Employee technical training annual Developing LIMS

Tasks of Lab of Microbiology( 微生物实验室的工作职责和任务） To monitor pathogens contaminating in environment (water,

air) , foods, air conditioners To monitor infectious diseases To do some research works for public health (especially in

detection methods, food safety, professional health, environment health)

To take part in dealing with public health emergency affairs To provide analysis data for surveillance and product safety. To participate in and issue quality control plan To provide professional and technical training for different

microbiology lab

Structure of Lab of Microbiology( 微生物实验室组成）

Bacteria monitoring and testing section Respiratory bacteria group Enterobacterium group Vector borne bacteria group Serum antibody surveillance group Virus monitoring and testing section Respiratory virus group Enterovirus group Hepatitis virus group Vector borne virus group Serum antibody surveillance group

Structure of Lab of Microbiology( 微生物实验室组成）

Lab of Microbiology

Bacteria section Viruses section

Respiratory bacteria group

Enterobacterium group

Surem antibody surveillance group

Vector borne Bacteria group

Respiratory virus group

Enterovirus group

Hepatitisvirus group

Arbonia virus group

Technical Platform of Lab of Microbiology

Pathogens isolation and identification Immunoassay (ELISA, IFA, etal) Molecular biology assay (PCR, PFGE, Ribo-print

er, DNA Sequence tests)

Pictures of Microbiology Lab

Lab corridor

A variety of microscope

More Pictures

Nucleic acid extraction

machine

Real-time PCR instrument

More Pictures

Temple for Bacteria counting

ATB for Bacteria identification

Bio-safety level-3 Laboratory

Main co-operate Items

Join in the Global Salmonella Surveillance (GSS)Join in the Pulse-Net Chine (which is co-operate

with Pulse-Net USA)Join in the WHO Influenza surveillance and

monitoring NetJoin in the foods safety and inspects surveillance in

China

Bacteria Monitoring & Testing Section

Monitoring salmonella, shigella, Vibro Cholera, E.Coli O157:H7, Vibro Parahemolyticus, staphylococcus aureus, campylobacter ， Listeria Monocytogenes et al in foods (pork, beef, seafood, milk, vegetables et al), water supply and diarrhea patients

Monitoring Legionalle bacillus in air conditioners, water distribution systems and patients

Monitoring Neisseria meningitis, Group A Streptococcus and other respiratory bacteria in patient and public areasy

Monitoring vector-borne pathegons Monitoring and testing pathogens in foodborne diseases and waterborn

e diseases Monitoring antibiotic sensitivity and antibiotic resistence Monitoring antibody level in population

Viruses Monitoring and Testing Section

Monitoring HAV ,HEV and Noro virus in seafood , water supply, riverhead and patients

Monitoring influenza and other respiratory viruses in publics and patients

Monitoring Avian influenza in publics and birds, poultries Monitoring Japanese Encephalitis virus, Dengue fever vir

us and Hanta virus, et al in mosquito, mouse and patients

Monitoring Hepatitis virus such as HBV, HCV, HEV in patients

Monitoring other diarrhea viruses in patients Monitoring hand-foot-mouth disease in children Monitoring virus-Antibody levels in population

Monitoring Results

Comma bacillus positive in HuangPu River and sea foods

Salmonella ,pathogenic E. coli positive in pork and beef

Parahaemorrhagic vibro positive in sea foods Legionella bacillus positive in water distribution s

ystems and central air conditioner chilled water supplys

HAV, Noro virus positive in sea foods Dengue virus, Japanese encephalitis virus negative in m

osquito and Hanten virus antibody positive in mouse

The situation of Communicable disease in Shanghai,2007

Name of diseaes

Number of patient

Rate of incidence(1/10,000)

Increase or decrease(%)

Cholera 1 0.01 -50.34

AIDS 58 0.42 98.65

Hepatitis 3309 24.09 -29.23

Measles 397 2.89 82.55

Rabies 4 0.03 -0.68

Japanese encephalitis

2 0.01 -

Dengue fever 1 0.01 -

The situation of Communicable disease (part) in Shanghai,2007

Name of diseases Number of patients

Morbidity

(1/10,000)

Increase or decrease(%)

bacillary dysentery 390 10.12 -52.75

TB 4296 31.28 13.72

Typhoid 68 0.50 -20.54

Epidemic cerebrospinal meningitis

5 0.04 24.15

Brucellosis 5 0.04 -

Gonorrhea 6054 44.05 -21.42

Syphilis 8747 63.69 8.35

Personal Experience

The Chief of Microbiology Lab Responsible for lab management, lab bio-safety,

including quality and technical management Over 20 years lab practice Familiar with pathogens isolation, identification a

nd molecular technique( such PCR and Real-time PCR)

Graduated from the School of Public Health, Fudan University

Personal Research Field

• Microbiology pollution surveillance and monitor in foods, water supply and central air conditioner

• Pathogenic organisms detecting and results analysis in communicable disease patients

• Pathogenic organisms rapid testing methods research

• Search for unknown pathogens which causes communicated disease

Goals of Fogarty Training

To understand the lab management here in California (lab safety, quality control)

To learn the research strategies and methods To learn the planning & preparing of bioterrorism To learn the public health emergency response

strategies To realize California’s culture, historical and

social environment To improve my English

Thanks for

Fogarty International Center of NIHCalifornia Department of Public Health,

EHIB &EHLBFaculty members of Fogarty International

Training ProgramAll members in EHIB and EHLB

THANK YOU !