Introduction to NeurobiologyLecture 8: Purkinje Cells 1

brain slices 2

brain slices 3

10 mV

100 ms

5 s

Spontaneous activity 4

Evoked activity 5

Distribution of potentials 6

Calcium activity 7

The different thresholds 8

10 mV

5 s

Bi stability 9

Bi stability 10

Bi stability 11

Bi stability 12

Transient current injection to the cell can toggle its state 13

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I

V

I

V

Current voltage curves and bistability 14

Climbing Fiber

Parallel Fiber

Complex and simple spikes 15

Climbing fibers response and Ca changes