Introduction to Clinical Pharmacy 2

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    Introduction to Clinical

    Pharmacy

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    Clinical Pharmacy

    Pharmacy service that isfocused on the patient rather

    than a product (the prescription).

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    Focus of Practice

    Selling a product

    Patient care

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    Clinical PharmacyDrug Information

    Hospital practice

    Clinic Practice

    Clinical research

    Clinical education

    Pharmaceutical Industry

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    Pharmaceutical CareIdentification, resolution, and prevention of drug-

    related problems.

    Untreated indications

    Improper drug selection

    Subtherapeutic dosage

    Failure to receive drugs

    Overdosage

    Adverse drug reactions

    Drug interactions

    Drug use without indication

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    Areas ofF

    ocus for ClinicalPharmacy Efforts

    Patient counselingDisease management

    Medication safety

    Drug Policy Management

    Clinical research

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    Common Diseases for Clinical

    Pharmacy Services

    Diabetes

    Hypertension

    Hyperlipidemia

    Infectious diseases

    Asthma

    Cancers

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    What Clinical Pharmacists Do

    Provide direct patient care

    Support physicians and nurses

    Write drug policies / formularies

    Conduct research

    Review and evaluate drug use

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    Clinical Pharmacy Services

    The patient who comes to your pharmacy

    Recommend the most appropriate non-prescription

    medication for the patients condition.

    Check to see if there are any interactions with other

    drugs.

    Assure there are no disease or allergy

    contraindications

    Provide recommendations for how to

    take the medication.

    Provide information about the drug

    or disease.

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    Clinical Pharmacy Services

    The patient in the hospital

    Perform medication history. Check to see that the drug dosage is appropriate.

    Check patient allergies.

    Provide medication counseling before the patientleaves the hospital.

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    Clinical Pharmacy Services

    The Hospital

    Evaluate published studies to determine

    which drugs should be used (Formulary)

    Answer drug information questions from

    physicians and nurses.

    Perform reviews of medication use

    (drug use evaluation)

    Write guidelines for drug use

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    Clinical Pharmacy Services

    The Community

    Offer disease screening (diabetes,osteoporosis, hyperlipidemia, hypertension)

    Offer lectures to community groups.

    Provide immunizations. Patient counseling.

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    Medical College of Georgia

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    The Medical College of Georgia Teaching hospital for the State of Georgia

    Medical, nursing, dental schools.

    Associated with University of Georgia College of

    Pharmacy.

    500 hospital beds, many clinics, trauma center

    Separate pediatric hospital 23 pharmacists, 45 pharmacy technicians

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    Clinical Pharmacy in Augusta,

    Georgia, USA

    Drug Information Center

    Renal transplantation service

    Oncology

    Pediatrics

    Intensive care unit

    Anticoagulation clinic

    Emergency room

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    Drug Information Center

    Answer questions from physicians and

    nurses.

    Review clinical studies on new drugs.

    Recommend drugs to add to hospital

    formulary.

    Conduct drug safety reviews.

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    Drug Information Center

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    DrugF

    ormulary A selected list of drugs that are

    recommended for use in a health care

    system. Most hospitals, government systems, and

    insurance companies have formularies.

    Should be based on evidence that theselected drugs are more effective, safer,

    or less expensive.

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    Promote Medication Safety

    Design prescribing, drug dispensing,

    and drug administration systems that

    reduce the chance of errors.

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    Clinical Pharmacist in Surgery Rounds with surgery team

    Assist with antibiotic selection

    Write policies for antibiotic use

    Pharmacokinetic dosing

    Design parenteral nutrition regimens

    Pain assessment and analgesic recommendations

    Provide drug information

    Patient counseling

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    Renal Transplant Service Assist in dosage adjustment

    for immunosuppressants

    (such as cyclosporine)

    Manage other chronic

    diseases (diabetes,

    hypertension, hyperlipidemia)

    Review drug regimens.

    Patient counseling and

    compliance monitoring.

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    Oncology Assure safety of cancer

    drug treatments.

    Provide drug information tophysicians and nurses.

    Provide information and

    counseling to patients.

    Assist with clinical studies.

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    Anticoagulation Clinic See patients after referred by physician.

    Monitor coagulation tests (such as prothrombin

    time). Check for adverse effects (bleeding).

    Provide education to patients.

    Encourage compliance.

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    Pediatrics

    Assist with determining the

    best dosage and route of

    administration.

    Create policies for drug use

    in children.

    Provide drug information tophysicians.

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    Intensive Care Service

    Trauma service and Medical Intensive Care

    Rounds with intensive care teams.

    Review drug regimens.

    Pharmacokinetic dosing.

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    New Clinical Pharmacy Areas

    in Georgia

    Wellness Clinic (disease screening)

    Immunization programs

    Disease management

    Clinical drug study management

    Medication Access Program

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    Wellness Clinic

    Disease screening (hypertension, diabetes,

    osteoporosis, hyperlipidemia)

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    Wellness Clinic

    Medication counseling for patients

    Immunizations

    Smoking cessation

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    Clinical Pharmacy ResearchPrinciple investigator or Co-investigator with

    physicians

    Pharmacokinetic studies

    Clinical efficacy trials

    Pharmaco-epidemiology

    Pharmaco-economics

    Post-marketing safety studies

    Quality of life / patient satisfaction studies

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    Trends in Pharmacy Automation of prescription dispensing

    function

    Increasing drug costs

    Greater need for drug information and

    assessment

    New drugs based on biomedical discoveries

    Patient concern for drug safety

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    Other Important TrendsAging of the population.

    Greater use of medications for chronicdisease.

    Introduction of new, expensive medications

    Shortage of physiciansIncreasing authority of nurses, physician

    assistants, and psychologists.

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    W

    ho Hires Clinical Pharmacists?Hospitals

    Community Pharmacies

    Drug Companies

    Physician groups

    Federal government

    Insurance companies

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    Documented Benefit of

    Clinical Pharmacists

    Decrease drug costs

    Decrease drug adverse effects

    Reduce mortality in hospitalized

    patients