Introduction to Basic Therapeutics Module

Dr. Naser Ashraf TadviModule coordinator

Objectives

• Describe the concept of Module, including objectives, learning contents, teaching and learning methodology, practicals, references, assessment, and all module related matter

• Understand computer assisted learning in experimental Pharmacology

• Briefly overview the concept of pharmacology

Concept of the Module

Theme I: Different Therapeutic Modalities

• Introduction to different therapeutic modalities.

• Non-pharmacological basis of therapy (e.g. physiotherapy, occupational therapy, radiotherapy, counseling & CAM)

• Introduction to pharmacotherapeutics

Theme II:

How body handles drugs (Pharmacokinetics): Absorption. Distribution. Metabolism. Elimination.

How drug acts (Pharmacodynamics): Receptors (affinity, efficacy & potency). Theory of drug receptors binding. Signal transduction apparatus. Therapeutic index and therapeutic window

Individual variations in drug response (pharmacogenomics) Introduction to Pharmacogenomics. Clinical relevance of Pharmacogenomics

Theme III: Autonomic Pharmacology & Autocoids

Autonomic nervous system drugs• Adrenergic agonists & antagonists.• Cholinergic agonists & antagonists.• Skeletal muscles relaxants.

Autacoids (histamine, serotonin & prostaglandins)• Histamine and antihistamines• Serotonin and anti–serotonin• Prostaglandins and ergot alkaloids

Theme IV: Rational & safe prescription

including drug development

• Drug therapy during pregnancy & lactation • Drug therapy in the geriatric & pediatric groups.• Adverse drug reaction (ADR).• Principles of toxicology.• Drug interactions • Safe prescribing habits.• Cost effective drug therapy.• Compliance & adherence • Monitoring of drug treatment• National & international drug evaluation & regulation

Teaching and learning methods

• Lectures: 30 • PBL: 4 • CD: 5• Seminars: 5• Practicals: 6• Tutorial: 2• Field Visit: 1

Practicals

• All practicals have Computer Assisted Learning • At the end of each practical the students will be

evaluated in the last half hour• The quiz for each practical will be of ten marks • MCQs or SEQs related to practical can be asked • There will be no separate mid term practical

exam • 10 % of these marks will be considered as

midterm practical exam marks

Assessment

• Continuous Assessment 60%• Final Assessment 40%

Continuous assessment Mid Module exam 20 %Multiple choice questions 60 marks 40 MCQs Short essay questions 40 Marks 05 SEQsActivities Marks 30 %Problem Based Learning (PBLs)

160 Marks 04 PBLs

Case Discussion (CDs) 75 Marks 05 CDsQuiz PBL, CDs, Seminars 40 Marks 04 Quiz Seminar 100 Marks 01 Seminar Mid Term Practical Exam Practical 2,3,4

30 Marks 10% of this

Mid module exam (will cover)

• Lecture 1 to lecture 15 • PBL 1 & PBL 2 • CD 1 & CD 2• Seminar 1 & Seminar 2

Quizzes (10 marks each)

• Quiz 1 – PBL 1, CD1, Seminar 1

• Quiz 2– PBL 2, CD2, Seminar 2

• Quiz 3– PBL 3, Seminar 3, CD 3

• Quiz 4– PBL 4, Seminar 4, seminar 5, CD4, CD5

Final Assessment

Final Assessment 40 %Final module examination 30 %Multiple choice questions 60 marks 60 MCQs Short essay questions 40 Marks 05 SEQsFinal Practical examination 10 %

Attendance

• 75 % attendance is compulsory for eligibility in exam

• PBLs, CDs, quizzes, practical's and Seminars absence will lead to loss of marks in continuous assessment

Concept of Pharmacology

• Drug therapy involves a great deal more than matching the name of the drug to the name of a disease; it requires knowledge, judgement, skill and wisdom, but above all a sense of responsibility.

Learning resources

• Illustrated reviews Pharmacology, Ed. Lippincott. 5th Edition,

• Katzung & Trevor’s Basic and Clinical Pharmacology. 12th Edition,

• Reference book: – Goodman & Gilman Pharmacological Basis of

Therapeutic 2011- 12th Edition

At the end of module