INTRODUCTION TO AUTOMOMIC PHARMACOLOGY: Part I: Why study autonomic pharmacology?
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Transcript of INTRODUCTION TO AUTOMOMIC PHARMACOLOGY: Part I: Why study autonomic pharmacology?
INTRODUCTION TO AUTOMOMIC PHARMACOLOGY:
Part I: Why study autonomic pharmacology?
Autonomic Pharmacologyis Rewarding!!
LOGICAL
CLINICALLYRELEVANT
+
Anatomical, Physiological &Neurobiological
Information
Predict Effects of Drugs
Mechanism of Drug Action
Autonomic Pharmacology is Logical
+
Drug A decreases activity of
organ Y
Autonomic Pharmacology is Logical
Drug A blocks receptors for
neurotransmitter X
Nerves to organ Y release neurotransmitter X,
and X increasesthe activity of organ Y
Autonomic Pharmacology is Clinically Relevant
Autonomic drugs are used for the
treatment of Angina
Autonomic drugs are used for the
treatment of Heart Failure
Autonomic drugs are used for thetreatment of
Alzheimer’s Disease
Autonomic drugs are used for the
treatment of High Blood Pressure
Autonomic drugs are used for thetreatment of
Benign Prostatic Hypertrophy
Autonomic drugs are used for the
treatment of Anaphylactic Shock
Autonomic drugs are used for the
treatment of Septic Shock
Autonomic drugs are used for the
treatment of Asthma