Introducing SRA’s New Global Health Sector to the

NVTC Health Technology Committee

April 2008

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Agenda

• About SRA

• Global Health Sector Capabilities– Research & Health Promotion– International Health Policy Promotion– Drug Development– Our People

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About SRA

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SRA Corporate Profile

• Global provider of innovative technology products, solutions, and professional services to public sector and commercial clients

• Founded in 1978; deeply embedded culture focused on creating real value for customers

• Publicly traded company (NYSE: SRX)

• IT services employer of choice—over 6,000 employees

• SRA core values– Ethic of honesty and service– Quality work and customer satisfaction– Great people dedicated to their work– Service to our country and communities

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Fairfax, VA (HQ)Arlington, VAAlexandria, VAFalls Church, VAFrederick, MDReston, VA

Sierra Vista, AZNewport Beach, CASacramento, CASan Diego, CAColorado Springs, COGlastonbury, CTFt Walton Beach, FLAtlanta, GAWarner Robins, GAFairview Heights, ILBoston, MABaltimore, MDColumbia, MDLandover, MDPax River, MDDurham, NCResearch Triangle Park, NC

BelizeEcuadorEl SalvadorGuatemalaGuyanaHaiti

BeninBotswanaBurkina FasoCameroonCape VerdeChadCote d’IvoireEthiopiaGhanaGuineaGuinea BissauKenyaLesothoLiberiaMadagascarMali

Latin America and Caribbean

Africa

HondurasJamaicaMexicoNicaraguaPanamaPeru

MalawiMozambiqueMauritaniaNamibiaNigerNigeriaRwandaSenegalSouth AfricaSwazilandTanzaniaTogoUgandaZambiaZimbabwe

Bath, UKOxford, UKCambridge, UK

Middle East

EgyptJordan

AfghanistanBangladeshChinaIndiaIndonesia

AustraliaMelbourne

Central and Eastern Europe

RussiaUkraineTajikistan

North America

West Europe

YemenLebanon

Cologne, GermanyParis, France

UzbekistanCroatia

Asia

JordanNepalPakistanThailandVietnam

McLean, VAVienna, VARockville, MDWashington, DC

Egg Harbor Township, NJ

Ft Monmouth, NJMt Arlington, NJShrewsbury, NJVegas, NVNew York, NYCincinnati, OHDayton, OHHatboro, PASan Antonio, TXChesapeake, VANewport News, VASeattle, WAMorgantown, WV

Global Presence

Working around the clock; working around the globe.Working around the clock; working around the globe.

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• Department of Defense– Department of the Army – Department of the Air

Force– Department of the Navy

and USMC– Joint Chiefs of Staff– Office of the Secretary of

Defense– DARPA– Defense Information

Systems Agency

– Defense Logistics Agency– Office of the Secretary of

Defense (Health Affairs)

• Department of Health and Human Services

• Department of Veteran Affairs• Department of Defense Health• USAID• UK Department for Int’l

Development• Bill & Melinda Gates

Foundation• European Commission• Biotech companies• Pharmaceutical companies• US State and Local

• Department of the Treasury• Environmental Protection Agency• Federal Deposit Insurance

Corporation• General Services Administration• Government Accountability

Office• Small Business Administration• US Agency for International

Development• US State and Local

SRA has a balanced portfolio of customers.SRA has a balanced portfolio of customers.

• Department of Agriculture• Department of Commerce• Department of the Interior• Department of Justice• Department of Labor• Department of Transportation

• Various intelligence agencies• Department of Homeland

Security• Department of Justice• State and Local Police, Justice,

and Homeland Security Departments

Who We Work With

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National Security and Civil Gov’t Key Programs

SRA isSRA is a leading provider ofa leading provider of technology and strategic consulting servicestechnology and strategic consulting services

ITSS for Department of Justice

• OJP processes applications and approvalsfor federal funds granted to state, local, and private organizations.

• Scope covers full range of IT services• Current tasks include DBMS services for US Trustee

Program and grants management system support for Office of Justice Programs

Defense Property System

• DOD has a $1.8B Personal Property Program that moves 500,000 shipments annually worldwide.

• Integrate Siebel and Manugistics to develop and maintain a Web-based system

• Support worldwide transfer of families as part of DoD“Families First” initiative

FDIC

• The 24x7 enterprise-wide information technology (IT) infrastructure management services we provide to FDIC support approximately 7,000 users at 94 field offices

• Scope includes client and help desk support; data center and local-area network operations; information security operations; systems and telecommunications engineering and integration support; and hardware/software procurement, distribution, and maintenance.

Pentagon Renovation

• The 50-year-old Pentagon is undergoing a complete renovation, constituting one of the region's largest public works projects on one of the world's largest buildings

• Specialized telecommunications and network engineering and integration services to renovate Pentagon

• Design, engineering, and implementation of Pentagon command centers

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Global Health Sector CapabilitiesGlobal Health Sector Capabilities

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Vision – Global Health Sector

Enhancing human health around the world, every day.

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Acquisition yields powerful synergies

• SRA’s acquisition of Constella added depth and breadth…– More than 1,500 professional staff in 60 countries– Thought leadership in key domains

• …leading to creation of new Sector – 2,000-person, $300M Global Health Sector – IT expertise plus health domain knowledge yield more

relevant solutions– Strong health research, health communications, clinical

trial, and policy and regulatory consulting expertise across public and private sector

– Shared values, goals, culture, and commitment to enhancing human health

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Public Health Informatics

Preparedness and biosurveillance systems

Laboratory Inspection

Public health monitoring and safety

Public Health Program Support

Consumer response hotlines

Health promotion and communications

Scientific peer review

Training & technical assistance

Health Research Technology

IT infrastructure and operations support

Research administration and applications

Bioinformatics systems development

Process Outsourcing

Systems engineering

Software development & operations

Data quality management

PMO support

Health Sciences Research

Clinical research

Experimental health studies

Survey research & evaluation

Healthcare Systems

Data modeling & warehousing

COTS deployment & integration

Enterprise architecture

Security & privacy services

IV&V

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Research and Health Promotion —Serving US Federal, State & Local Gov’t

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BioSense& BIC

CDC

Monitor potential disease outbreaks in the U.S.

For this early health-event detection and situational awareness surveillance system, SRA builds and manages the relationships with state/local public health and the health data sources (hospitals) on behalf of CDC.

SRA data analysts staff the BioIntelligence Center (BIC) utilizing the BioSense system and other related data sources.

Clinical Research Support ServicesNIEHS

Study impacts of environmental agents on human health.

SRA’s responsibilities span study planning, implementation, and analysis for both observational clinical research studies and interventional clinical trials.

National Practitioner Data Bank HRSA

Collect adverse information on medical practitioners and provide it to registered health-care entities.

SRA manages this fully-outsourced program, providing policy analysis, full life-cycle systems development for system upgrades, complete operations (help desk, reporting), and systems engineering and administration

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Representative ProjectsTechnology + Domain Expertise + Rigorous Process

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Policy Development

Developing and implementing public health policies

Mobilizing NGOs and civil society

Resource planning for service delivery

Engaging multiple sectors in policy formulation process

Tools to inform policy and programmatic decision making

Health System Strengthening

Evidence-based research, monitoring and evaluation

Modeling and forecasting

Patient monitoring and management Surveillance and epidemiology

Training and capacity building

Communications & Social Marketing

Fostering public-private sector partnerships to expand service delivery

Applying marketing principles encouraging healthy behaviors

Improving quality of health commodities and services

Stimulating commercial markets for health products

Fostering long-term sustainability of programs

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International Health Policy Promotion —Serving Nations and Their People

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Health Policy InitiativeUSAID

Foster an improved enabling environment for health.

Focusing on HIV/AIDS, FP/RH, and maternal health, we assist government and civil society partners in policy advocacy and formulation in more than 30 countries around the world and assist in-country partners in designing national and sub-national HIV policies and strategic plans.

MEASURE EvaluationUSAID

Increase the demand for quality data, methods, and tools and facilitate information use in decision-making.

For this project covering HIV/AIDS, family planning, maternal and child health and nutrition, malaria, and tuberculosis, we are charged with strengthening monitoring and evaluation functions/systems, and building in-country institutional capabilities.

ENHANSE, NigeriaUSAID

Create the enabling environment to improve policies, plans and financing for health and education.

We increase local capacity to better plan, conduct advocacy, use information, and develop policies in connection with a substantial local grants program.

In Nigeria, our work is aimed at promoting and sustaining access to high-quality health and education programs in HIV/AIDS, malaria, TB, child survival, FP, RH, safe motherhood, and basic education.

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Representative ProjectsTechnology + Domain Expertise + Rigorous Process

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Clinical Research

Management and monitoring of international Phase I-IV clinical studies

Feasibility studies

Quality Assurance

Expert auditing and quality assurance consulting services

Preparation of Quality Management Systems and Standard Operating Procedures

Biometrics

Comprehensive data management and statistics services

Specialized statistical consulting services

Pharmacovigilance

Management of serious adverse events from clinical trials

Pre-marketing and post-marketing safety consulting services

Regulatory Affairs

Drug development strategy, planning and management

Regulatory agency interactions and filings

Medical writing including clinical study reports

Strategic Consulting

Clinical Development Plans

Protocol Design

Opinion Leader Panels

Due Diligence

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Global Drug Development —Serving Pharma & Biotech

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Clinical management of a program of studies in diabetes

Develop a novel monocolonalantibody that is aimed at preventing the onset of Type I diabetes.

SRA conducted the initial early phase studies, and the company is ready to move into Phase II. SRA will be providing project management, monitoring and data management and statistics for the whole program.

Clinical trial for an HIV vaccine

Evolve new vaccine to prevent further deterioration of CD4 counts in HIV patients.

SRA provides all regulatory and clinical support for this project, which supports a new vaccine that could also be used in the future to stop HIV infected patients developing AIDS.

One of the key reasons for the award was the breadth of our HIV experience across multiple market segments.

EU regulatory submission and approval for a combination anti-hypertensive

Acquire EU approval for an anti-hypertensive with diuretic.

SRA obtained European approval the anti-hypertensive last year, and for the combo has just compiled the European regulatory filing and filed it in all 27 European countries in parallel. This submission involved translations into all European languages and production of 2 million pieces of paper.

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Representative ProjectsTechnology + Domain Expertise + Rigorous Process

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Our PeopleOur People

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« Nationally recognized expert in laboratory assessment and performance evaluation

« Frequent speaker at American Biological Safety Association (ABSA) and other industry groups

« VP and Director of the Center for Health Solutions, Constella Futures

« 20 years of HIV/AIDS research and programmatic experience in the Caribbean and the developing world

« Former Assistant Secretary of HHS« Responsible for implementing $5.6

billion Bioshield Project of 2004« Led national preparedness

planning for potential Avian Flu pandemic

« Served as Policy Advisor at HHS« Member of President’s Task

Force on Health Reform« Received the Surgeon General’s

Medallion, among other honors for public health service

« 30 years of public service in occupational and environmental health

« Retired Commissioned Officer in U.S. Public Health Service

« Served as Chief of Staff for Director, NIEHS

Thought Leaders Inform Strategic Planning

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What Others Say About Us