Intralesional Injections of Corticosteroid For Treatment of Active Osseous Lesions in Cherubism
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POSTER PRESENTATIONS PE-001 - AN ATYPICAL PRESENTATION OF EXTENSIVE MULTIFOCAL EPITHELIAL HYPERPLASIA: CASE RE- PORT IN IMMUNOCOMPETENT GIRL. THAÍS ALINE OLIVEIRA MACIEL, THÂMARA MANOELA MARINHO BEZERRA, CLARISSA FAVERO DEMEDA, BÁRBARA VANESSA DE BRITO MONTEIRO, ANA MIRYAM COSTA DE MEDEIROS, ÉRICKA JANINE DANTAS DA SILVEIRA, LEÃO PEREIRA PINTO. UNIVERSIDADE FEDERAL DO RIO GRANDE DO NORTE. Multifocal epithelial hyperplasia (MEH) is an uncommon lesion characterized by multiple lesions on the mouth associated with human papillomavirus (HPV) 13 and 32. Girl, 9, had mul- tiple nodular sessile and pedunculated lesions over a wide range of sizes (5 to 15 mm) located in palate, lips, and dorsum of the tongue. Her mother reported that the lesions appeared spontane- ously 6 months previously and that no family members showed similar lesions. The clinical diagnosis was D1-MEH and D2- condyloma acuminatum. The largest lesions on the tongue and lower lip were excised under local anesthesia and submitted for histopathological examination, which identified MEH. The pa- tient had no recurrences over the next 7 months. This condition sometimes resolves spontaneously within a few months or years, but the treatment is surgical excision because of the presence of numerous exophytic lesions that compromised the function and aesthetics of the patient. PE-002 - BURKITT LYMPHOMA: CASE REPORT. MAR- CELA RAMOS ABRAHÃO ELIAS, MARÍLIA OLIVEIRA MORAIS, JEAN CARLOS BARBOSA FERREIRA, GEISA BADAUY LAURIA SILVA, ELISMAURO FRANCISCO DE MENDONÇA. UNIVERSIDADE FEDERAL DE GOIÁS. Burkitt lymphoma is a highly aggressive neoplasm arising from B lymphocytes. It affects children and adolescents with a predilection for males and involvement of the gnathic bones, mainly the jaw. Radiographs show radiolucent destruction with poorly defined irregular margins. Microscopy revealed mono- morphic small lymphocytes and immature and undifferentiated interspersed with macrophages having abundant cytoplasm. Treatment is based on chemotherapy. Survival rates of 5 years are between 75% and 95%, depending on disease stage at diagnosis. Boy, 3, had swelling in the mandibular left with painful symp- toms. Imaging examination of the face revealed an osteolytic lesion causing jaw destruction. Ultrasound of the abdomen detected a solid lesion of the right kidney. Incisional biopsy was done on the oral lesions, followed by histopathological analysis that indicated high-grade Burkitt lymphoma. A chemotherapy protocol was indicated, and the patient is being closely monitored. PE-003 - INTRALESIONAL INJECTIONS OF CORTICO- STEROID FOR TREATMENT OF ACTIVE OSSEOUS LESIONS IN CHERUBISM. PATRICIA ROCON BIANCHI, TÂNIA REGINA GRÃO VELLOSO, ROSA MARIA LOURENÇO CARLOS MAIA, ROSSIENE MOTTA BERTOLLO, TERESA CRISTINA RANGEL PEREIRA, LILIANA APARECIDA PIMENTA DE BARROS, DANIELA NASCIMENTO SILVA. UNIVERSIDADE FEDERAL DO ESPÍRITO SANTO. The gold standard treatments for cherubism lesions include re-establishment of the jaw contour, curettage of lesions, and management of dental disharmony. However, for extensive lesions that can cause severe aesthetic and functional damage if surgery is not used, less invasive therapies should be consid- ered. Young woman, 16, had cherubism with active osseous lesions. Treatment was undertaken using intralesional injections of corticosteroid. The benefits of this therapy include it less invasive nature, lower cost, less risk, and delay in the need for surgery. However, negative aspects are the prolonged treat- ment, the need for a minimum of two injections a month, and a lack of long-term results. This clinical case report of a rare lesion shows the results obtained with less invasive therapy, helping to characterize clinical responses more securely and predictably. PE-004 - MULTIPLE FOCI OF ORAL DYSPLASIA AND ORAL SQUAMOUS CELL CARCINOMA IN A LARGE ERYTHROLEUKOPLASTIC LESION. SÉRGIO HENRIQUE GONÇALVES DE CARVALHO, GUSTAVO PINA GODOY, GUSTAVO GOMES AGRIPINO, MARIA QUITÉRIA FREITAS DE OLIVEIRA, DMITRY JOSÉ DE SANTANA SARMENTO, SANDRA APARECIDA MARINHO, JOSÉ CADMO WANDERLEY PEREGRINO DE ARAÚJO FILHO. FACULDADES INTEGRADAS DE PATOS/UNIVERSIDADE ESTADUAL DA PARAÍBA CAMPUS VIII. Oral carcinomas are epithelial malignancies and a public health problem because of their high incidence and morbidity. Characteristics include multifactorial origin, affecting gener- ally male patients, occurring after the fifth decade of life, and occurring in those who indulge in chronic tobacco and alcohol use and long-time sun exposure. Caucasian woman, 79, came to the Stomatology Service of Faculdades Integradas de Patos complaining of a lesion in the lip commissure. The large erythroleukoplakia involved the lips and left cheek mucosa but had included no palpable lymph nodes. Incisional biopsy specimens showed many areas of the lesion evidenced mild and moderate dysplasia as well as infiltrative squamous cell carcinoma. Strict evaluation of the various clinical fea- tures that oral squamous cells carcinoma can assume is necessary. It is important to perform multiple biopsies over an extensive area to make an early diagnosis and obtain a better prognosis. PE-005 - PERIPHERAL ADENOMATOID ODONTO- GENIC TUMOR PRESENTED AS A GINGIVAL SWELLING: CASE REPORT. TIFFANY TAVARES, TAIARA DE OLIVEIRA COSTA, MÔNICA SIMÕES ISRAEL, FABIO RAMOA PIRES. UNIVERSIDADE DO ESTADO DO RIO DE JANEIRO. Adenomatoid odontogenic tumor (AOT) is a rare tumor that has a peripheral variant which can manifest as gingival swelling. Peripheral AOT is more commonly found in women and at the maxilla. Caucasian girl, 11, presented with a gingival swelling of 1 year duration located on the attached and free labial gingival margin, apical to the upper permanent left central incisor. The lesion was normochromic, with soft to firm consistency. No signs or symptoms such as pain, bleeding, discharge, or fever were present; oral hygiene was inadequate. The involved tooth showed mobility and a diffuse periapical radiolucency on radiographic examination. The differential diagnosis included pyogenic granuloma, peripheral giant cell granuloma, peripheral ossifying fibroma and focal mucinosis. The lesion was enucleated, and transoperative OOOO ABSTRACTS Volume 117, Number 2 Abstracts e133
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Transcript of Intralesional Injections of Corticosteroid For Treatment of Active Osseous Lesions in Cherubism
OOOO ABSTRACTS
Volume 117, Number 2 Abstracts e133
POSTER PRESENTATIONS
PE-001 - AN ATYPICAL PRESENTATION OF EXTENSIVEMULTIFOCAL EPITHELIAL HYPERPLASIA: CASE RE-PORT IN IMMUNOCOMPETENT GIRL. THAÍS ALINEOLIVEIRA MACIEL, THÂMARA MANOELA MARINHOBEZERRA, CLARISSA FAVERO DEMEDA, BÁRBARAVANESSA DE BRITO MONTEIRO, ANA MIRYAM COSTADE MEDEIROS, ÉRICKA JANINE DANTAS DA SILVEIRA,LEÃO PEREIRA PINTO. UNIVERSIDADE FEDERAL DORIO GRANDE DO NORTE.
Multifocal epithelial hyperplasia (MEH) is an uncommonlesion characterized by multiple lesions on the mouth associatedwith human papillomavirus (HPV) 13 and 32. Girl, 9, had mul-tiple nodular sessile and pedunculated lesions over a wide rangeof sizes (5 to 15 mm) located in palate, lips, and dorsum of thetongue. Her mother reported that the lesions appeared spontane-ously 6 months previously and that no family members showedsimilar lesions. The clinical diagnosis was D1-MEH and D2-condyloma acuminatum. The largest lesions on the tongue andlower lip were excised under local anesthesia and submitted forhistopathological examination, which identified MEH. The pa-tient had no recurrences over the next 7 months. This conditionsometimes resolves spontaneously within a few months or years,but the treatment is surgical excision because of the presence ofnumerous exophytic lesions that compromised the function andaesthetics of the patient.
PE-002 - BURKITT LYMPHOMA: CASE REPORT. MAR-CELA RAMOS ABRAHÃO ELIAS, MARÍLIA OLIVEIRAMORAIS, JEAN CARLOS BARBOSA FERREIRA, GEISABADAUY LAURIA SILVA, ELISMAURO FRANCISCO DEMENDONÇA. UNIVERSIDADE FEDERAL DE GOIÁS.
Burkitt lymphoma is a highly aggressive neoplasm arisingfrom B lymphocytes. It affects children and adolescents with apredilection for males and involvement of the gnathic bones,mainly the jaw. Radiographs show radiolucent destruction withpoorly defined irregular margins. Microscopy revealed mono-morphic small lymphocytes and immature and undifferentiatedinterspersed with macrophages having abundant cytoplasm.Treatment is based on chemotherapy. Survival rates of 5 years arebetween 75% and 95%, depending on disease stage at diagnosis.Boy, 3, had swelling in the mandibular left with painful symp-toms. Imaging examination of the face revealed an osteolyticlesion causing jaw destruction. Ultrasound of the abdomendetected a solid lesion of the right kidney. Incisional biopsy wasdone on the oral lesions, followed by histopathological analysisthat indicated high-grade Burkitt lymphoma. A chemotherapyprotocol was indicated, and the patient is being closely monitored.
PE-003 - INTRALESIONAL INJECTIONS OF CORTICO-STEROID FOR TREATMENT OF ACTIVE OSSEOUSLESIONS IN CHERUBISM. PATRICIA ROCON BIANCHI,TÂNIA REGINA GRÃO VELLOSO, ROSA MARIALOURENÇO CARLOS MAIA, ROSSIENE MOTTABERTOLLO, TERESA CRISTINA RANGEL PEREIRA,LILIANA APARECIDA PIMENTA DE BARROS, DANIELANASCIMENTO SILVA. UNIVERSIDADE FEDERAL DOESPÍRITO SANTO.
The gold standard treatments for cherubism lesions includere-establishment of the jaw contour, curettage of lesions, and
management of dental disharmony. However, for extensivelesions that can cause severe aesthetic and functional damage ifsurgery is not used, less invasive therapies should be consid-ered. Young woman, 16, had cherubism with active osseouslesions. Treatment was undertaken using intralesional injectionsof corticosteroid. The benefits of this therapy include it lessinvasive nature, lower cost, less risk, and delay in the need forsurgery. However, negative aspects are the prolonged treat-ment, the need for a minimum of two injections a month, and alack of long-term results. This clinical case report of a rarelesion shows the results obtained with less invasive therapy,helping to characterize clinical responses more securely andpredictably.
PE-004 - MULTIPLE FOCI OF ORAL DYSPLASIA ANDORAL SQUAMOUS CELL CARCINOMA IN A LARGEERYTHROLEUKOPLASTIC LESION. SÉRGIO HENRIQUEGONÇALVES DE CARVALHO, GUSTAVO PINA GODOY,GUSTAVO GOMES AGRIPINO, MARIA QUITÉRIAFREITAS DE OLIVEIRA, DMITRY JOSÉ DE SANTANASARMENTO, SANDRA APARECIDA MARINHO, JOSÉCADMO WANDERLEY PEREGRINO DE ARAÚJO FILHO.FACULDADES INTEGRADAS DE PATOS/UNIVERSIDADEESTADUAL DA PARAÍBA CAMPUS VIII.
Oral carcinomas are epithelial malignancies and a publichealth problem because of their high incidence and morbidity.Characteristics include multifactorial origin, affecting gener-ally male patients, occurring after the fifth decade of life, andoccurring in those who indulge in chronic tobacco andalcohol use and long-time sun exposure. Caucasian woman,79, came to the Stomatology Service of Faculdades Integradasde Patos complaining of a lesion in the lip commissure. Thelarge erythroleukoplakia involved the lips and left cheekmucosa but had included no palpable lymph nodes. Incisionalbiopsy specimens showed many areas of the lesion evidencedmild and moderate dysplasia as well as infiltrative squamouscell carcinoma. Strict evaluation of the various clinical fea-tures that oral squamous cells carcinoma can assume isnecessary. It is important to perform multiple biopsies over anextensive area to make an early diagnosis and obtain a betterprognosis.
PE-005 - PERIPHERAL ADENOMATOID ODONTO-GENIC TUMORPRESENTEDASAGINGIVAL SWELLING:CASEREPORT. TIFFANY TAVARES, TAIARA DE OLIVEIRACOSTA, MÔNICA SIMÕES ISRAEL, FABIO RAMOA PIRES.UNIVERSIDADE DO ESTADO DO RIO DE JANEIRO.
Adenomatoid odontogenic tumor (AOT) is a rare tumorthat has a peripheral variant which can manifest as gingivalswelling. Peripheral AOT is more commonly found in womenand at the maxilla. Caucasian girl, 11, presented with agingival swelling of 1 year duration located on the attachedand free labial gingival margin, apical to the upper permanentleft central incisor. The lesion was normochromic, with soft tofirm consistency. No signs or symptoms such as pain,bleeding, discharge, or fever were present; oral hygiene wasinadequate. The involved tooth showed mobility and a diffuseperiapical radiolucency on radiographic examination. Thedifferential diagnosis included pyogenic granuloma, peripheralgiant cell granuloma, peripheral ossifying fibroma and focalmucinosis. The lesion was enucleated, and transoperative
