International Osteoporosis Foundation AnnuAl RepoRt 2012 · InternatIonal osteoporosIs FoundatIon...

International Osteoporosis Foundation

AnnuAl RepoRt 2012

www.iofbonehealth.org

2 InternatIonal osteoporosIs FoundatIon AnnuAl RepoRt 2012

IoF membeRs woRk togetheR to mAke bone, joInt And muscle heAlth A woRldwIde pRIoRIty

InternatIonal osteoporosIs FoundatIon AnnuAl RepoRt 2012 3

message from the president and ceoLooking back, 2012 was undoubtedly among the most dynamic and productive years in IOF’s history.

Above all, it was marked by unprecedented outreach on many fronts.

In terms of scope, IOF moved beyond the borders of osteoporosis to reach out to the chronic disease community, while expanding its remit to encompass muscle and joint health.

With the election of a new Board of Governance, for the first time with equal representation from each region, IOF completed the final phase of its regional development strategy. This was further strengthened by Regional Advisory Councils in all three regions in which IOF maintains regional offices.

For the first time, IOF regional meetings were successfully staged in four regions of the world: Asia-Pacific, Europe, Latin America and the Middle East & Africa. In all, more than 7000 health care professionals profited directly from outstanding opportunities for education and research through IOF meetings and training courses. The new ‘IOF Young Investigator Mentoring Programme’, held as pilot programmes in Jordan and Kuala Lumpur, was well received by the participants. This programme underscores IOF’s strong commitment to the promotion of science and research across cultures and borders.

IOF’s Committee of Scientific Advisor Working Groups continued their impressive work, publishing nine reviews and statements on topics of importance to the bone, muscle and joint field. And, there’s much more in the pipeline for 2013!

In regard to public outreach, IOF launched a stimulating new website featuring modern design and new interactive mapping content. The new site serves as a portal which offers individual membership options and online access to IOF’s scientific publications. Over time IOF will build a community of many thousands of individual members in the musculoskeletal field.

The World Osteoporosis Day ‘Stop at One’ campaign resounded widely, with significant media impact that reached millions of consumers and health care professionals on all continents. The theme underlined IOF’s dedication to secondary fracture prevention and its new ‘Capture the Fracture’ programme to promote the implementation of fracture liaison services worldwide.

These many new developments have set the stage for the coming year, during which we look forward to consolidating and expanding our effective programmes in science and public outreach.

john A. kanisPRESIDEnT

judy stenmarkChIEF ExECuTIvE OFFICER


the oRgAnIzAtIon

about IoF

MIssIon

The International Osteoporosis Foundation’s (IOF) is the world’s leading nGO dedicated to the fight against osteoporosis and related musculoskeletal diseases

IOF was founded in 1998 as a not-for-profit, international non-governmental foundation registered in Switzerland. The Foundation functions as a global alliance of patient, medical and research societies, scientists, healthcare professionals and corporate partners across many fields.

IOF headquarters are in nyon, Switzerland, with regional representations in Latin America (Buenos Aires, Argentina), Asia-Pacific (Singapore), Middle East & Africa (Dubai, uAE). IOF has been granted Roster Consultative Status with the Economic and Social Council of the united nations.

IOF’s mission is to promote the maintenance of bone, muscle and joint health as a worldwide priority.

Goals• Motivate people to take action to maintain musculoskeletal health and prevent, diagnose and

treat bone, muscle and joint disorders

• Foster the education and training of physicians and allied health care professionals in the field of musculoskeletal health and bone, muscle and joint disorders

• Lobby for policy change so that musculoskeletal health and the prevention, diagnosis and treatment of bone, muscle and joint disorders becomes standard worldwide

• Promote medical innovation and to improve patient care in the field of musculoskeletal health

• Support and maintain contacts with institutions or societies having similar objectives

three MeMbershIp Groups*

Committee of national Societies (CnS) Comprises patient and medical societies dedicated to osteoporosis and bone health. In 2012 the CnS included 209 member societies from 94 countries, regions or territories across all continents.

Committee of Scientific Advisors (CSA) Comprises 122 of the world’s top research and clinical experts, elected to the committee by their peers on the basis of scientific merit and experience. The CSA ensures that IOF has an influential and important global reach in the science and medical arena.

Committee of Corporate Advisors (CCA) Represents 32 companies from diverse areas of activity, including leading companies in pharmaceuticals, medical diagnostics, consumer products, food and nutrition, banking, and advertising.

For further information and for a full listing of the committees, membership benefits and how to join, visit the IOF website.

* membership as of December 2012

Peter Ebeling AUSAmbrish Mithal IND

hajime Orimo JPNEgo Seeman AUS

John Kanis GBREugene McCloskey GBR

Socrates Papapoulos NEDJean-Yves Reginster BEL

Gemma Adib SYRStephen hough RSA

Basel Masri JORLeith Zakraoui TUN

jouRnAl edItoRs Roberto Civitelli USA Robert Lindsay USA Stuart Ralston GBR

pResIdent John A. KanisgeneRAl Bess Dawson-hughes secRetARytReAsuReR René Rizzoli csA chAIR Cyrus Cooper cns chAIR José Zanchetta

csA chAIR Cyrus Cooper

csA VIce-chAIR Serge Ferrari

cns chAIR José Zanchetta

cns VIce-chAIR Jean-Yves Reginster

pAtIent socIetIes sub-commIttee chAIR Famida Jiwa

ccA chAIR Laurence Alliot

ccA VIce-chAIR norma Piggott

Jonathan Adachi CANJohn Bilezikian USA

Bess Dawson-hughes USAharry Genant USA

new board oF Governance elected A new Board structure designed to give equal representation to all five regions (each region with four elected members) was introduced in 2012. The newly elected members of the Board, as well as ex-officio members, took their seats for the first time in March 2012, beginning a four year term until 2016. In Asia-Pacific, Latin America, Middle East & Africa, where IOF has regional administrative offices, two of the four Board members in each region were elected by the regional CnS and the remaining two were elected by the global membership. In Europe and north America, where IOF does not have administrative offices, all four seats were elected by the global membership.

asIa-pacIFIc reGIon

european reGIon

latIn aMerIca recIon

ex-oFFIcIo MeMbers

executIve coMMIttee (Dec. 2012)

coMMIttee chaIrs

north aMerIcan reGIon

IoF busIness MeetInGsBordeaux, France March, 2012• Board, CnS, CSA, CCA

Minneapolis, uSA october, 2012• Board, CCA

IOF Business Meetings in Bordeaux, France

chanGes In IoF senIor ManaGeMentThe IOF Executive Committee regretfully accepted the resignation of IOF Chief Executive Officer (CEO) Patrice McKenney effective June 30, 2012. Ms McKenney was commended for her invaluable services to IOF over the past three years. Former IOF Chief Operating Officer (COO) Judy Stenmark was appointed as CEO (as of July 1, 2012). A new COO is expected to join IOF in March 2013.

elected board MeMbers

Patricia Clark MEXOsvaldo Messina ARG

Cristiano Zerbini BRA José Zanchetta ARG

MIddle east & aFrIcan reGIon


IoF lAtIn AmeRIcA

325

IoF euRope

11666

IoF AsIA-pAcIFIc

3221

IoF mIddle-eAst & AFRIcA

227

A global membership dedicated to musculoskeletal health

IoF noRth AmeRIcA

723

* members listed according to IOF Regions and based on membership in December 2012. The full list of IOF members can be viewed on the IOF website at www.iofbonehealth.org/about-us

cns Members csa Members209 patient & medical societies 122 scientific experts


With the launch of its new website platform (see page 23), IOF also launched a new membership option for interested individuals around the world. via the website, individuals can register as IOF members (at no charge) to receive considerable benefits, including online access to the IOF journals Archives of Osteoporosis and Progress in Osteoporosis, regular e-news including the

monthly bulletin ‘BoneBlast’, and discounts at IOF Scientific Meetings. For a yearly fee of 50 uSD (25 USD for WHO designated low-income countries) individuals can opt for the ‘Pro2’ membership which additionally gives online access to the journals Osteoporosis International and Calcified Tissue International.

In 2012, IOF completed the important process of regionalization that began in 2009. now, with four elected Board members from each of the five regions, there is equitable representation at IOF’s highest level of governance.

IOF’s Regional Programme is designed to facilitate collaboration among the member associations in three designated regions: Asia Pacific, Middle East & Africa, and Latin America. These are the regions which benefit from a local IOF regional office. Latin America held its first elections for a Regional Advisory Council (RAC) in 2012, so that all three of the targeted regions now have well-functioning RAC councils (see list in the respective regions shown in this report).

Through its regionalization programme IOF aims to:

• develop a strong regional structure based on collaboration of local societies, with programmes and policies targeted to the regions’ specific needs

• assIst the regions to acquire the resources needed to educate health professionals and empower patients

• strenGthen osteoporosis associations worldwide to better serve the needs of the patients and health professionals in the region

IoF buIlds a worldwIde coMMunIty oF IndIvIdual MeMbers

IoF reGIonalIzatIon proGraMMe proGressInG well


AsIA-pAcIFIc

reGIonal advIsory councIl• chair Ambrish Mithal IND• Suthorn Bavonratanavech THA• Siok Bee Chionh SGP• hiroshi hagino JPN• Tai-Pang Ip HKG, CHN• Sarath Lekamwasam LKA• Philip Sambrook AUS

ex-officio IoF board members

• Edith Lau HK, CHN• hajine Orimo JPN• Ego Seeman AUS

new MeMbers In 2012

cns • Endocrinological and Diabetes Association of uzbekistan (EDAu) • Pakistan Society for the Rehabilitation of the Disabled

csa • Manju Chandran SGP • Samuel vasikaran AUS

cca • Inner Mongolia Mengniu Dairy (Group) Co., Ltd.

IoF young InVestIgAtoR awards & MentorInG proGraMMeAt the IOF Regionals in Kuala Lumpur, young researchers from five countries won prestigious IOF awards valued at 1000 uSD each for their highest ranking abstracts. The winners were from Australia, China, India, Pakistan and Singapore.

In Kuala Lumpur, on December 13, 2012, IOF held the 2nd IOF Young Investigator Mentoring Programme. This important new initiative of IOF, held for the first time in the Asia-Pacific Region, invites a select number of young investigators to attend an exclusive hands-on course led by a renowned faculty of experts. The course teaches practical skills and provides insightful feedback that are of great value to the young scientists as they further their careers in bone research.

Rhonda ngIOF ASIA-PACIFIC COORDInATOR

The eminent Australian rheumatologist and longstanding CSA member passed away on March 31, 2012. Professor Sambrook had been elected to the IOF Regional Advisory Council for the Asia-Pacific Region.

IoF polIcy ActIon In asIaFormer IOF CEO Patrice McKenney joined the Malaysian Osteoporosis Society and the Osteoporosis Awareness Society of Kuala Lumpur at a meeting with the office of the Minister of health in Kuala Lumpur to encourage the government of Malaysia to give osteoporosis greater priority within the healthcare system. The CEO also met with the health Promotion Board in Singapore to talk about public education initiatives around bone health and the relevance of osteoporosis as a chronic disease.


3rd asIa-pacIFIc osteoporosIs MeetInG kuAlA lumpuRThe IOF Regionals 3rd Asia-Pacific Osteoporosis Meeting in Kuala Lumpur from December 13-16, 2012 was the largest IOF Regionals meeting to date. At the Opening Ceremony, IOF was honoured to welcome the Deputy Minister of health of Malaysia, YB Datuk Rosnah bt. hj. Abd. Rashid Shirlin; his Excellency Tun Dato’ Seri utama (Dr) haji Abdul Rahman bin haji Abbas, Governor of Penang; and world-star Dato Seri Michelle Yeoh. With a high-quality scientific programme and more than 400 abstracts the Meeting was a key educational and research event in the Region.

mIchelle yeoh leads MedIa event In Kuala luMpur

At a press event preceding the scientific meeting in Kuala Lumpur, internationally acclaimed actress and bone health advocate Michelle Yeoh urged Malaysians to take action to look after their bone health. her statements attracted considerable local and regional media coverage on behalf of bone health.


woRld osteopoRosIs dAy events across asIanational societies across the region marked World Osteoporosis Day 2012 through a wide array of public awareness events, conferences, media campaigns and health professional workshops. Overall, millions of citizens across the region heard the ‘Stop at One’ message of secondary fracture prevention.

Of the many excellent World Osteoporosis Day events organized throughout Asia, one of the most impressive was a huge event in Jakarta, Indonesia, hosted by the Indonesian PERWATuSI and PEROSI with IOF and Fonterra Brands. IOF CEO Judy Stenmark joined the Indonesian Deputy Minister of health and other policy makers and vIPs as key speakers. For complete information visit www.worldosteoporosisday.org/tags/asia-pacific


euRope

new MeMbers In 2012

csa • Bo Abrahamsen, DNK • Muhammed Kassim Javaid, GBR

cns • Italian Federation of Osteoporosis & Diseases of the Skeleton (FEDIOS) • Society for Osteoporosis in Federation Bosnia & herzegovina • 1.6 Million Club (Sweden) • Georgian Association of Skeletal Metabolism Diseases • Italian COPD Patient Association

IoF-ecceo12 In boRdeAux – europe’s Key bone event

The European Congress on Osteoporosis & Osteoarthritis, held in Bordeaux, France from March 21-24, 2012, was one of the premier bone events of the year. Attracting more than 4000 delegates, the Congress presented the latest clinical research and offered a high quality scientific programme of plenary lectures, topical symposia, meet-the-expert sessions, satellite symposia and a large exhibition. In conjunction with the Congress, the 2nd IOF-ESCEO Pre-Clinical Symposium featured the latest in translational research.

IoF joIns ey2012 coAlItIonIOF became a member of the European Year for Active Ageing and Solidarity between Generations coalition, a group of some 40 European organizations aiming to promote innovative solutions to economic and social challenges facing the ageing European population.

musculoskeletAl heAlth RoundtAble In cyprushosted by IOF and the Cyprus Society Against Osteoporosis and Musculoskeletal Diseases, the Musculoskeletal health Roundtable held in Cyprus on September 6, 2012 was honoured to welcome Dr Stavros Malas, Cyprus Minister of health. Dr Malas stated, “healthy ageing is a top priority for the Cyprus Eu Presidency.”

ncd allIance networK achIeves breaKthrouGhAt the end of May 2012 in Geneva, long-term efforts by nCD advocates resulted in the 65th World health Assembly adopting the ‘25 by 25’ target which aims to reduce preventable deaths from non-communicable diseases (nCDs) by 25 per cent by 2025. IOF applauded this important outcome, which recognizes the burden of non-communicable diseases, including musculoskeletal disorders, on the health of the global population.


snAp! exhIbItIon In GenevaThe first outdoor, month-long exhibition of Snap! the breaking spine took place along Quai Wilson on Lake Leman in Geneva. Snap! is IOF’s unique photographic exhibit which reveals the daily life of six people living with spinal osteoporosis in Brazil, Canada, India, Jordan and Switzerland. The exhibition was also shown alongside IOF’s information desk at Place de la Fusterie during World Osteoporosis Day 2012. www.iofsnap.org

woRld osteopoRosIs dAy hIGhlIGhts In europeEuropean members of IOF’s Committee of national Societies carried out numerous events, to spread the World Osteoporosis Day message of secondary fracture prevention to patients, the general public, health professionals and media. For example, patient forums and community or hospital events were held in Bulgaria, Czech Republic, Denmark, Greece, Germany, hungary, Italy, The netherlands, Portugal, Spain, Romania, Russia, Switzerland. For complete information visit: www.worldosteoporosisday.org/tags/europe

her Royal highness The Duchess of Cornwall, President of the uK’s national Osteoporosis Society, was photographed with fracture patients on the occasion of World Osteoporosis Day.

A press event launching the Capture the Fracture report (see page 25) in Europe was organized by IOF with Prof Maria-Luisa Brandi of F.I.R.M.O and in collaboration with S.E. Monsignor Zygmunt Zimoski. Other notable speakers included IOF President John Kanis, SIOT President Prof. M. D’Imporzano and football legend Paolo Rossi. The October 18 event resulted in high profile coverage of osteoporosis in Italy.

13

lAtIn AmeRIcA

reGIonal advIsory councIl• chair José Zanchetta ARG REGIÓN CONO SUR (AR, CL, PY, UY): • Claudia Campusano CHL BRASIL • Bruno Muzzi BRA REGIÓN ANDINA (CO, ECU, BO, PE) • Dr. Luis vidal neira REGIÓN CARÍBE (VE, CENTRAL AMERICA, CARIBBEAN ISLANDS) • Sonia Cerdas CR MÉXICO • Fidencio Cons Molina MEX

ex-officio IoF board members

• José Zanchetta ARG• Patricia Clark MEX• Osvaldo Messina ARG• Cristiano Zerbini BRA

mónica calóIOF LATIn AMERICA COORDInATOR

IoF RegIonAls In são paulo The 1st Latin America Osteoporosis Meeting in São Paulo attracted more than 700 specialists and general practitioners from over 32 countries. held in Portuguese, Spanish and English, the meeting presented recent research from the region and provided an update on latest clinical practice.

latIn aMerIca RegIonAl AudItLaunched on May 24, the Audit was the first to compile epidemiological data and quantify the burden of osteoporosis and fractures in Latin America. Covering 14 countries in the region, the Audit warned of the impending explosion in the number of fractures as the ageing population surges in most countries. In some countries hip fractures will more than double by 2050. The media launch generated extensive coverage in television and print throughout the region.

new MeMbers In 2012

cns • Brazilian Society for Rheumatology • venezuelan Society of Osteoporosis Patients (OSTEOAMIGOS)

In 2012, the bone community in Brazil lost two respected and well-loved members. IOF Board Member Rubem Lederman died on April 16 at the age of 76. He had served on the Board from 1999 to March 2012. Well known rheumatologist Sergio Ragi Eis, died on February 22. Dr. Ragi had had been elected to the IOF Regional Advisory Council in Latin America.

IoF young InVestIgAtoR awards The IOF Sergio Ragi-Eis Young Investigator Award was awarded to the five highest scoring abstracts by researchers under the age of 40. The award, named in honour of the late Brazilian clinician and researcher, was awarded to young researchers from Brazil and Argentina.


woRld osteopoRosIs dAy In latIn aMerIcaActivities were carried out in some 10 countries in Latin American, including in Argentina, Brazil, Costa Rica, Chile, Ecuador, Mexico, Panama, venezuela, and uruguay. The World Osteoporosis Day website was available in Spanish and Portuguese to reach out to Latin American communities.

IOF joined the Sociedad Argentina de Osteologia y Metabolismo Mineral (AAOMM) and the Fundación de Investigaciones Metablicas (FIM) to stage a World Osteoporosis Day walk in a central location in Buenos Aires. For complete information visit www.worldosteoporosisday.org/tags/latin-america

IoF traInInG courses In latIn aMerIcaosteoporosis and celiac disease course The multidisciplinary course focuses on issues related to osteoporosis and the treatment of patients with celiac disease. The 3º course was held on October 26, in Buenos Aires, Argentina - a total of 80 professionals were trained.

IoF paediatric bone health training course This one-day course designed for paediatricians and other health professionals was held in Buenos Aires in July 2012 and in Mexico City in August 2012, with more than 250 participants.

IoF symposia health professionals participated at informative IOF-led symposia held in conjunction with national societies. Symposia were held at the xII Asociación Méxicana de Metabolismo Ósea y Mineral Congress in veracruz, Mexico and the xxx International Congress on Obstetrics and Gynecology in Buenos Aires, Argentina.

serving the online community in latin america

The huES.O.S website at www.ayudaatushuesos.com brings information to the general public in Spanish, providing prevention tips, recipes, the One Minute Risk Test, and much more.


mIddle eAst & AFRIcA

hanady khalifeIOF MIDDLE EAST & AFRICA COORDInATOR

IoF RegIonAls dead sea, jordanThe 2nd Middle East & Africa Osteoporosis Meeting & PAOC6, which closed on Sunday September 30 was a resounding success, attracting more than 550 delegates to the spectacular venue at the Dead Sea, Jordan. Speakers at the Opening Ceremony included the Jordanian Minister of health Dr Abdul Latif Wreikat (middle in picture), and the Palestinian health Minister, Dr hani Abdeen. IOF thanks PAOS, JOPS, JPOS, and POPS for the excellent collaboration.

reGIonal advIsory councIl• hazem Abdel Azeem EGY• Gemma Adib SYR• Tobias De villiers ZAF• Basel Masri JOR• Jamal Saleh BHR• Eghbal Taheri IRN• Leith Zakraoui TN

new MeMbers In 2012

csa Mohammed-Salleh Ardawi, SA

cns The Algerian Society for Rheumatology

FIVe young InVestIgAtoRs awarded In jordanAt the Jordan Meeting, IOF recognized the work of young researchers, granting IOF Young Investigator Awards of 1000 uSD to the five highest ranked abstracts by researchers aged 40 and under.

pIlot mentoRIng proGraMMeIn conjunction with the Dead Sea meeting, a total of 17 young researchers from the region were invited to take part in the first IOF Young Investigator Mentoring Programme. This was the pilot session introducing a series of exclusive hands-on workshops that will take place at IOF Regionals in the future.


woRld osteopoRosIs dAy awareness caMpaIGns In the MIddle east & aFrIca IOF Middle East and Africa regional office, in partnership with the Emirates Osteoporosis Society (EOS), carried out successful World Osteoporosis Day events with the support of Dubai health Authority and the Emirates Medical Association. Other activities, ranging from media campaigns to public and health professional education, took place in Egypt, Iran, Jordan, and South Africa, among others. In Jordan, a popular television show was devoted to bone health, and in Iran, Osteoporosis Week saw both Tv advertising and more than 10 000 educational pamphlets distributed in metro stations in Tehran. Read about these and other events in the Middle East & Africa at: www.worldosteoporosisday.org/tags/middle-east-africa


noRth AmeRIcA

woRld osteopoRosIs dAy launch In MInneapolIsThe north American launch of the new IOF Capture the Fracture report was held on October 11, 2012 at a well-attended event in Minneapolis, hosted by IOF together with the national Osteoporosis Foundation (nOF), national Bone health Association (nBhA) and Osteoporosis Canada. IOF’s World Osteoporosis Day focus on secondary fracture prevention was perfectly aligned with the nBhA’s 2Million2Many campaign, which is working to improve post-fracture care and support for patients with the goal of reducing the 2 million bone breaks that occur every year in the country.

new MeMbers

cns California hispanic Osteoporosis Foundation

Image courtesy of the 2Million2Many campaign.


scIence

commIttee oF scIentIFIc AdVIsoRs worKInG Groups

IOF’s Committee of Scientific Advisors (CSA) develops important scientific programmes and publishes influential reviews, guidelines and position papers. CSA members are active in 12 working groups and participate in multinational research projects.

In 2012 the CSA Working Groups published nine key reviews and position papers, continuing a productive trend that has seen a surge of influential papers published over the past three years.

key posItIon And ReVIew pApeRs publIshed In 2012•Lekamwasam S et al., A framework for the

development of guidelines for the management of glucocorticoid-induced osteoporosis (joint position with ECTS). Osteoporosis International

•Lekamwasam S et al., An appendix to the 2012 IOF-ECTS guidelines for the management of glucocorticoid-induced osteoporosis. Archives of Osteoporosis

•Diez-Perez A et al., Treatment failure in osteoporosis. Osteoporosis International

•Kanis JA et al., European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporosis International (joint IOF-ESCEO publication)

•Kanis JA et al., A systematic review of hip fracture incidence and probability of fracture worlwide. Osteoporosis International

•Ferrari S et al., Osteoporosis in young adults: pathophysiology, diagnosis and management. Osteoporosis International

•Cooper C et al., Long term treatment of osteoporosis in postmenopausal women: a review from ESCEO and IOF. Current Medical Research and Opinion

•Mithal A. et al., Impact of nutrition on muscle mass, strength and performance in older adults. Osteoporosis International

•Wahl D et al., A global representation of vitamin D status in healthy populations. Archives of Osteoporosis

IoF - at the ForeFront oF MusculosKeletal research and health proFessIonal educatIon

• bone and cancer working Group Chair René Rizzoli

• bone Imaging working Group Co-chairs Mary Bouxsein, harry Genant

• csa education steering committee Chair: Ego Seeman

• epidemiology/Quality of life working Group Co-chairs Cyrus Cooper, John A. Kanis

• Fracture working Group Chair Kristina Åkesson

• Inadequate responders working Group Chair Adolfo Diez Perez

• IoF-ects Glucorticoid-induced

osteoporosis Guidelines working Group Chair Juliet Compston

• IoF-IFcc bone Marker standards working Group Co-chairs Cyrus Cooper, with IFCC

• IoF-IsFr distal radius Fracture Chair Amy hoang-Kim

• nutrition working Group Chair Ambrish Mithal

• paediatrics working Group Chair Serge Ferrari

• skeletal rare disease Chair Maria Luisa Brandi


do-health study

IOF is a partner in a new international study that was launched on February 3 at the university of Zurich. The DO-hEALTh study (vitaminD3-Omega3-home Exercise-healthy Ageing and Longevity Trial), Europe’s largest healthy ageing study, expects to provide evidence for the efficacy and safety of three simple preventive interventions: vitamin D, omega-3 fatty acids and a simple home exercise programme.

InteRActIVe Mapsvitamin d Map

•Overview of the vitamin D status in healthy populations worldwide

•Based on 200 studies from 46 countries

•Two age categories: children (<18 years) and adults

•Four colour coding according to mean (or median) vitamin D levels

Frax Map

•10-year probability of a major osteoporotic fracture

•Data from 45 FRAx models available in 40 countries

•Colour coding according to probability (%) designated as low, intermediate and high

hip Fracture Incidence Map

•Data from 63 countries

•Colours according to risk designated as high, medium or low

•Maps for women, men and both sexes combined


FRAxIOF supports the development of, and logistical support for, the WhO Fracture Risk Assessment Tool (FRAx®). FRAx, which assesses 10-year probability of fracture, is being used by clinicians around the world to make informed treatment decisions. In 2012, FRAx version 3.7 was released and models made available for 47 countries/territories and in 24 languages.

FRAx is freely available online at www.shef.ac.uk/FRAX. It is offered in several interface options and can be licensed as an iPhone App or desktop application at www.who-frax.org.

publIshInG leadInG scIentIFIc journals

osteoporosis International Editors in Chief John A Kanis and Robert Lindsay

Joint journal of IOF and nOF (uSA) Impact factor: 4.580 in 2011 Ranked 25th among 121 journals in the category Endocrinology and Metabolism

calcified tissue International Editors in Chief Roberto Civitelli and Stuart Ralston

Monthly peer reviewed journal dedicated to original research on the biology and mechanisms of metabolic bone diseases. Impact factor 2011: 2.376

archives of osteoporosis Editors in Chief John A Kanis and Robert Lindsay

A joint online journal of the IOF and nOF(uSA). Joint online journal of IOF and nOF (uSA) now PubMed indexed!

progress in osteoporosis Editor Ego Seeman

Online open access review journal with more than 10,000 readers. Re-launched as a monthly publication in 2012, the journal now offers a discussion option. www.iofbonehealth.org/pio


FuRtheRIng health proFessIonal educatIon & research advances

In 2012 IOF held, for the first time, key scientific and educational meetings in each of four world regions. Altogether more than 7000 delegates attended IOF meetings or training courses in Asia-Pacific, Europe, Latin America and Middle East & Africa. Featuring the latest clinical research and high standards of CME-accredited health professional education, IOF meetings have become leading bone events around the world.

IoF’s FlAgshIp tRAInIng couRse In GenevaThe 21st IOF Advanced Training Course on Osteoporosis was held from January 31-February 2, 2012 in Geneva Switzerland. Chaired by Professor Socrates Papapolous, IOF’s flagship training course for up to 200 delegates offers CME accreditation and is led by a renowned faculty. The course has provided comprehensive training in osteoporosis to more than 4000 health professionals over the past two decades.

IoF regionals - 3rd asia-pacific osteoporosis Meeting

Kuala Lumpur, Malaysia • December 13 - 16, 2012

IoF regionals - 2nd Middle east & africa osteoporosis Meeting

Dead Sea, Jordan September 27 - October 1, 2012

IoF regionals 1st latin america osteoporosis Meeting

São Paulo, Brazil • May 24 - 27, 2012

european congress on osteoporosis and osteoarthritis (IOF-ECCEO12)

Bordeaux, France March 21 - 24, 2012

2nd IoF-esceo pre-clinical symposium

Bordeaux, France March 23 - 24, 2012

May

24-272012

December

13-16 2012

Sept-Oct

27-12012

March

21-242012

March

23-242012

IoF endorseMent oF membeR socIety meetIngsEach year IOF provides support for a selected number of meetings and conferences held by its member societies, either through endorsement, provision of speakers and/or funding. The meetings are listed on the IOF website at www.iofbonehealth.org/past-meetings-and-events


IoF Medal of achievement

Professor Cyrus Cooper was the recipient of this important award in recognition of his outstanding research contributions to the epidemiology of osteoporosis.

IoF pierre d. delmas award

Professor Bess Dawson-hughes was presented with IOFs Pierre D. Delmas Award in recognition of her significant and unstinting contribution to the advancement of the work of the IOF.

IoF-servier young Investigator research Grant

This valuable grant of 40 000 EuR was awarded to Dr Mark Edwards, clinical research fellow at the MRC Lifecourse Epidemiology unit at Southhampton General hospital in the uK, to support research on relationships between body composition, muscle and bone strength.

coMMunIcatInG IoF scIence newsvia regular e-blasts and its monthly newsletter ‘BoneBlast’, IOF communicates science news to a large database of interested health professionals, members and policy makers. In addition, regular press releases issued via the scientific news agency EurekAlert serve to highlight important guidance and position papers to an audience of more than 8000 health journalists worldwide.

pierre delmas prize: an esceo-IoF-servier achievement award

This important award was presented to Professor Rene Rizzoli, Professor of Medicine at the university hospitals of Geneva, in recognition of his outstanding work in the area of metabolic bone diseases, osteoporosis and bone nutrition.

2nd herbert a. Fleisch esceo-IoF Medal

The eminent Danish researcher Dr Claus Christiansen was honoured for his pioneering work in many areas, including the development of densitometry, markers of bone turnover and clinical trials.

IoF AwARds presented In bordeaux


globAl outReAch & public Awarenessnew IoF websIte expands bone, Muscle and joInt health outreachIn March 2012 IOF re-launched its website www.iofbonehealth.org with a modern new design, new content and an enhanced and improved user-experience. The website’s new features include an interactive national society finder map, interactive maps, and new sections with information on osteoarthritis and sarcopenia (reflecting IOF’s broadening focus on bone, muscle and joint disorders).

IOF’s community outreach is supported by a growing number of visitors to our active Twitter and Facebook pages.

osteolInk OsteoLink is the first online and in-person social network for people with osteoporosis, their friends, families, and healthcare professionals in Europe and Australia. An initiative of the International Osteoporosis Foundation and the Division of Bone Diseases at the Faculty of Medicine, university of Geneva, OsteoLink operates globally and at the country level, working with our network of IOF member national Societies. OsteoLink is currently available in Australia, Austria, Sweden and Switzerland with more countries launching soon.

www.osteolink.org

World Osteoporosis Day (WOD) on October 20th marks the pinnacle of a year-long campaign to educate and spread awareness of osteoporosis and bone health around the world. Each year the IOF-led WOD campaign reaches out to the public and patients, health professionals, media and policy makers. IOF’s more than 200 member societies are provided with campaign publications and posters in seven languages and are encouraged to use these tools for their own national WOD campaigns.

IOF’s popular 2012 WOD campaign focused on the important issue of secondary fracture prevention. Although fractures have enormous personal and health-economic impact, over 80% of people who experience fractures are neither diagnosed nor treated for osteoporosis. In an effort to close the care gap, IOF issued a new report directed at health professionals and a patient-oriented campaign under the ‘Stop at One’ banner – calling on all adults over 50 to ask for osteoporosis testing following a first fracture.

Stop at oneMake your first break your last

WorldOsteoporosisDayOctober20

25

stop At one MaKe your FIrst breaK your lastThe clear message on posters and brochures calls on fracture patients aged 50 and over to insist on testing and treatment to prevent secondary fractures.

Campaign materials and an events listing are available on the newly designed World Osteoporosis Day website www.worldosteoporosisday.org.

cAptuRe the FRActuRe a Global caMpaIGn to breaK the FraGIlIty Fracture cyclePublished for World Osteoporosis Day, this informative report calls for concerted worldwide efforts to stop secondary fractures due to osteoporosis through the implementation of coordinator-based models of post-fracture care. The report is available in seven languages on the IOF website.


IoF staff

patrIce McKenney Chief Executive Officer (to July 2012)

judy stenMarK Chief Operating Officer (to July 2012) Chief Executive Officer (from July 2012)

nadIa aKhMIsse Meeting Manager

sIlKe collIns tracey Policy Manager (to March 2012)

carolIne coolen Office Manager (from October 2012)

carey Kyer Science Project Manager (as of July 2012)

aGeeth van leersuM-FrIKKee Science Administrator

GIlberto lontro Senior Graphic Designer, Multimedia Producer

lIhI MaIre Office Manager (to October 2012)

shannon Mcdonald Science Coordinator (to July 2012)

carolIne Muller Finance Manager

anthony nGuyen Communications Coordinator (as of July 2012)

doMInIQue pIerroz Science Manager

lohes rajeswaran Policy Coordinator (to May 2012)

suvI saxen Meeting Manager Asia-Pacific

evI rossettI Accounts Coordinator

caleb starrenburG Online Communications Coordinator (to May 2012)

nurcan tosun Development Coordinator

laurence trIouleyre Committee of national Societies Coordinator

Interns

a specIal thanKs For the hard worK oF our Interns ChRIS AuCOIn Graphic & Web Design EDGARD GOnZALEZ Meetings BREnnDA MATTOS Meetings IRA ThOMS Meetings

consultants

FIna lIu Managing Scientific Editor

laura MIstelI Communications Editor

donna spaFFord Senior Policy Consultant

asia-pacific office Singapore

rhonda nG IOF Asia-Pacific Regional Coordinator

jacQuelIne lye IOF Asia-Pacific Regional Assistant

latin america office Argentina

MónIca caló IOF Latin America Regional Coordinator

vIctorIa barrachIna IOF Latin America Regional Project Coordinator

Middle east & africa office uAE

hanady KhalIFe IOF Middle East & Africa Regional Coordinator

Majd zeItoun IOF Middle East & Africa Regional Assistant

IOF staff at headquarters in nyon, Switzerland and in regional offices in Dubai, Buenos Aires and Singapore, are responsible for carrying out the many IOF projects and programmes as well as fundraising, member services and liaison, publication management and congress/meeting organization.


Administration and Finance

From a financial standpoint I am pleased to report a 24% increase in revenue for 2012. The proportionally lower increase (17%) in operating expenditure reflects the increased output in the area of regional meeting organization. Consequently we have also seen a strong and welcome increase in the operating gain in 2012 of 582 000 ChF as compared to 186 000 ChF in 2011.

Both fundraising and congress organization play a central role in terms of IOF operations and staff responsibilities. Within one year, with its relatively small staff, IOF successfully staged four large regional meetings and the annual training course in Geneva. This was accomplished while advancing an array of new and ongoing programmes, an extensive World Osteoporosis Day campaign and the publication of the first Latin American Regional Audit. These accomplishments deserve recognition! Congratulations to the staff for their tremendous efforts and a job well done.

Investment income and expenditure have remained stable and we hope that 2013 will see significant growth in this area.

On behalf of IOF I would like to thank our Committee of Corporate Advisors as well as other corporate sponsors who have shown their continued commitment to IOF. Their support has permitted us to increase public and health professional outreach more than ever before.

I would also like to acknowledge our auditors, BDO, for their expert and timely services.

As we head into 2013 we look forward to another year of extensive programming and positive growth based on a healthy and stable financial foundation.

René RizzoliIOF TREASuRER

Financial statements

Financial Income and expenditure

2012 2011

Financial income 450 577 489 190

Financial expenses 632 245 660 638

Financial loss for the year - 181 668 - 171 448

Operating gain for the year 582 074 186 152

total gain for the year 400 406 14 704

operating expenses

2012 2011

Science 2 611 628 1 755 274

IOF Family 710 663 700 350

Promoting Policy Change 210 257 342 125

Outreach and Education 1 165 641 1 281 741

Total Programs and Projects 4 698 189 4 079 490

Management and administration 999 358 762 998

Fundraising 124 765 120 377

Total Supporting Services 1 124 123 883 375

operating revenues

2012 2011

Science 4 322 998 2 134 125

IOF Family 317 906 584 264

Promoting Policy Change 130 921 457 045

Outreach and Education 1 435 140 1 516 167

Total Programs and Projects 6 206 965 4 691 602

Other income 197 421 457 415

total operating revenues 6 404 386 5 149 017

total operating expenses 5 822 312 4 962 865

operating gain for the year 582 074 186 152

OPERATInG ACCOunT FOR ThE YEAR EnDED DECEMBER 31, 2012 in ChF

Other income

Outreach and Education

Promoting Policy Change

IOF Family

Science

6 404 386 chF

detail ‘the 206: a bone Fund’

2012 2011

Revenues 181 954 101 164

Expenses 91 465 93 437

Increase/(decrease) of ‘the 206: a bone Fund’ 90 489 7 727

assets

2012 2011

Current assets 4 713 549 4 963 581

Fixed assets 2 724 108 3 870 934

total assets 7 437 657 8 834 515

liabilities

2012 2011

Short-term liabilities 998 879 2 870 390

Long-term liabilities 1 348 451 1 527 428

total liabilities 2 787 228 4 397 818

‘the 206: a bone Fund’

2012 2011

Opening balance 932 925 925 198

Increase/(decrease) 90 488 7 727

Liquidation of ‘The 206: A Bone Fund’

- 1,023,413 0

closing balance 0 932 925

donation capital

2012 2011

Opening balance 3 503 773 3 489 069

Gain/(loss) for the year 400 406 14 704

Liquidation of ‘The 206: A Bone Fund’

1 023 413 0

closing balance 4 927 592 3 503 773

total liabilities, ‘the 206: a bone Fund’ and donation capital 7 437 657 8 834 515

The figures indicated on pages 28-30 have been extracted from the statutory financial statements for 2012 which have been subject to a limited statutory examination by BDO SA. The full set of the statutory financial statements for 2012 and the report of BDO SA are available upon request at the IOF Secretariat, nyon.

Notes to the Financial Statementsstatement of expenses

program and projects direct project costs

employee costs

supporting services

total expenses

2012

total expenses

2011

science World-class scientific conferences 1 394 728 303 188 103 222 1 801 139 998 948

Support innovative research 131 473 189 226 64 423 385 122 165 373

Expand professional awareness 298 092 10 650 3 626 312 369 354 609

Training 226 265 51 977 17 696 295 937 331 235

Others 6 027 6 028 13 613

Total 2 056 586 555 041 188 968 2 800 596 1 863 779

IoF Family Expand the network 773 2 057 700 3 531 15 129

Service Members 288 998 39 502 13 449 341 948 416 279

Total Internal meetings and conferences 220 190 159 142 54 181 433 514 337 362

Total 509 962 200 701 68 330 778 993 768 770

promoting policy change

Convince decision makers (publications, meetings) 81 559 54 290 18 483 154 333 238 142

Increase ability of IOF network to lobby for policy change 41 078 33 329 11 347 85 755 151 188

Total 122 637 87 620 29 831 240 088 389 330

outreach and education

Assisting IOF members to raise public awareness 33 172 7 536 40 708 43 274 15 100

Assisting IOF members to provide the public energy 187 697 66 893 254 590 277 364 248 885

Assisting IOF members to develop education programs 357 508 53 129 410 638 428 726 1 035 195

Fundraising materials 376 108 83 596 459 704 497 729 64 457

Total 954 486 211 154 38 025 1 247 094 1 363 637

total program and projects 3 643 672 1 054 517 368 581 5 066 771 4 385 517

supporting services

Management and Administration 304 882 694 475 -397 277 602 081 424 231

Raising money from existing and new sources (Fundraising) 40 479 84 286 28 696 153 461 153 117

Total 345 362 778 761 -368 581 755 542 577 348

total expenses 3 989 034 1 833 278 0 5 822 312 4 962 865

AS OF DECEMBER 31, 2012 in ChF

International osteoporosis Foundation - usa, Inc.

In order to establish a legal presence in north America “International Osteoporosis Foundation - uSA, inc” was established on December 2, 2004 as a not-for-profit corporation organized under the not-For-Profit Corporation Law of the State of new York.

In 2012 a correction of ChF181,494.60 (uSD191,127.42) is booked related to an error on the inclusion of the IOF uSA, Inc. accounts in the 2010 financial statements. This correction has no impact on IOF’s capital build-up: the gain for the year of 400,460.20 ChF is added to capital.

As of December 31, 2012, International Osteoporosis Foundation - uSA, Inc owes to the Foundation 107,049 ChF (2011: 268,677 ChF).

risk assessment

A risk analysis was performed in December 2010 by the CEO and IOF’s President. The risk analysis was presented to the Board in March 2011. In December 2011 the risk assessment performed in 2010 was updated by the CEO and IOF’s President and presented to the Board in March 2012.

the 206 a bone Fund

Following a decision by the Board of the Foundation, the 206 A Bone fund was liquidated during 2012. The assets invested in securities was combined with IOF’s investments and the fund’s capital was added to IOF’s capital. This decision was taken because the 206 A Bone fund had served it’s purpose over the years and the application of the assets and capital are similar to those of IOF’s main assets and capital.


conGresses, conFerences and traInInG courses

european congress on osteoporosis & osteoarthritis IoF-ecceo12 (bordeaux, France)dIaMond Rottapharm/Madaus ServierplatInuM Amgen/GSKGold MSD

IoF regionals 1st latin-america osteoporosis Meeting (sao paolo, brazil)platInuM GSKGold Eli Lilly Servierbronze MSD nestlé Faz Bem Sanofi

IoF regionals 2nd Middle east & africa osteoporosis Meeting (dead sea, jordan)dIaMond Amgen/GSKGold Eli Lilly nestlé ServiersIlver GE healthcare hyatt Pharma hologic MSD novartis

IoF regionals 3rd asia-pacific osteoporosis Meeting (Kuala lumpur, Malaysia)platInuM ServierGold GSK Eli Lilly MSDbronze Fonterra

IoF advanced training course on osteoporosis (Geneva, switzerland)Eli Lilly Grant OfficePfizer

health proFessIonal educatIon/researchcsa working GroupsAmgen/GSK Medtronic

symposium at eFort congressAmgen

vitamin d Maps Pfizer Consumer healthcare DSM

young Investigator Mentoring programmeServier Eli Lilly

vitamin d meeting, brusselsDSM

specIal projectscapture the FractureEli Lilly Medtronic MSD Servier

osteolinkAmgen/GSK

snap!Eli Lilly

websIteServier Warner Chilcott

Grants, awards and FellowshIps

IoF servier young Investigator awardServier

world osteoporosIs day

nestlé MSD Fonterra Amgen/GSK Pfizer Consumer healthcare

latIn aMerIca

IoF logo agreementDanone Argentina S.A. Danone uruguay nestlé Argentina nestle Brazil Danone Brazil

latin america regional auditGold sponsor GSK other sponsors Servier Danone Brazil Danone Mexico

children bone health courseMexico Danone de Mexico S.A. de C.v.

Argentina Danone Argentina S.A. Eli Lilly Argentina S.A. novonordisk Argentina S.A. Roux Ocefa

osteoporosis & celiac disease workshop (argentina)Montpellier S.A.

la outreach & communication related projectsFarma venezuela S.A. MSD de Mexico S.A. de C.v. Servier Ecuador novartis Argentina Danone Argentina Danone urugay Danone México GSK Argentina

IoF thanks 2012 corporate sponsors & partners


DESIGn Gilberto domingues lontro IOF • LAYOuT chris aucoin IOF • COvER PhOTO Gilberto domingues lontro • ©2013 International Osteoporosis Foundation

International osteoporosis Foundation9 rue Juste-Olivier • CH-1260 Nyon • Switzerland • t +41 22 994 01 00 • F +41 22 994 01 01 • [email protected] • www.iofbonehealth.org

International Osteoporosis Foundation AnnuAl RepoRt 2012 · InternatIonal osteoporosIs FoundatIon...

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