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aDRAFT

+82-2-2223-7000

Conference Chair:

Laurence Klotz, MDWUOF Chairman (Canada)

WUOF Steering Committee:

Peter Black, MD (Canada)Sung Kyu Hong, MD (Korea)

Ji Youl Lee, MD (Korea)Alessandro Volpe (Italy)

INTERNATIONAL ISSUES IN UROLOGIC ONCOLOGY

www.wuof.org

Conference Chair | Laurence Klotz, MDMeeting Room: Ballroom B Hanra - Level 3FWELCOME & INTRODUCTIONS

7:15 Meet and Greet International Colleagues (coffee and refreshments served) 7:45 Framing of Theme | Laurence KlotzALL SCREENING TALKS 7 MINUTES FOLLOWED BY 3 MINUTE Q & A 7:50 SESSION ONE | PROSTATE CANCER SCREENING & PREVENTION | Co-Moderators: Ji Youl Lee & Laurence Klotz 7:55 Prostate Cancer Screening: European Perspective | Franz Recker, MD 8:05 Prostate Cancer Screening: American Perspective | Matthew Cooperberg, MD 8:15 Prostate Cancer Screening: Japanese Perspective | Shin Egawa, MD 8:25 Prostate Cancer Screening: Latin American Perspective | Arturo Mendoza-Valdés, MD 8:35 PSA Cutpoint Should be 1.5 | David Crawford, MD 8:45 FSH and Prostate Cancer | Jehonathan Pinthus, MD

9:00 DISCUSSION (10 mins)

9:10 SESSION TWO | PROSTATE CANCER MANAGEMENT OPTIONS | Co-Moderators: Yves Fradet & Sung Kyu Hong

CLINICAL CASE: | Management of Grade Group 2 Prostate Cancer | TBA (5mins)

9:15 CASE & DEBATE – MANAGEMENT OF GRADE GROUP 2 PROSTATE CANCER • Surveillance | Sung Kyu Hong, MD (10 mins) • Focal Therapy | Rafael Sanchez-Salas, MD (10 mins) • Radical Therapy | Neil Fleshner, MD (10 mins) 9:45 DISCUSSION (10 mins) 9:55 Can Ultrasound Imaging Replace MRI? | Peter Hammerer, MD10:07 Can MRI Replace Prostate Biopsy | Guillaume Ploussard, MH, PhD10:19 Integrating Imaging and Biomarkers in Prostate Cancer Diagnosis | Derya Tilki, MD10:29 DISCUSSION (10 mins)

10:40 SESSION THREE | KIDNEY CANCER | Co-Moderators: Allesandro Volpe & Ofer Yossepowitch

10:42 Challenges in Cystic Renal Tumours | Makarand Khochikar, MD10:54 Angiogenesis Markers in RCC | Hanjong Ahn, MD11:06 Where to Draw the Line Between Radical and Partial Nephrectomy? | Peter Mulders, MD11:18 Adjuvant Therapy in RCCPost Nephrectomy | Robert Flanigan, MD11:30 DISCUSSION (5 mins)

11:35 WORKING LUNCH Complimentary Meal to All Seated Participants Attending Session Four Working Lunch

12:00 SESSION FOUR | TOWN HALL

EMERGING DIAGNOSTIC BIOMARKERS IN PROSTATE CANCER | Moderator: Laurence Klotz

Introduction by Matthew Cooperberg: The Unmet Need for Liquid Biopsy in the Diagnostic PathwayKEY OPINON LEADERS: EMERGING BIOMARKERS – WHAT IS THE LATEST DATA?

12:10 Topic TBA | miR Scientifi c | Martin Tenniswood, PhD 12:20 Emerging Biomarkers in Prostate Cancer | MDx Health | Jack Schalken, MD 12:30 Radiogenomics I Robert Reiter12:40 PANELISTS: | “BIOMARKERS IN PROSTATE CANCER” Current Role of Molecular Biomarkers in the Management of Prostate Cancer: Which Ones and Why? 12:40 Panelist One I Shin Egawa, MD 12:45 Panelist Two I Marc Dall’Era, MD 12:50 Panelist Three I Robert Reiter 12:55 Panelist Four I Derya Tilki, MD 1:00 OPEN DISCUSSION (30 mins) | Panelists & Industry Only

1:30 SESSION FIVE | PROSTATE CANCER TREATMENT OPTIONS | Co-Moderators: Damien Bolton & John Davis

1:32 Improving the Outcome of Men on Active Surveillance | Marc Dall’Era, MD 1:44 RP in Men Over Age 75: Is it Folly? | Shomik Sengupta, MD 1:56 Advances in MR-U/S Fusion Guided | Art Rastinehad, MD 2:08 DISCUSSION (10 mins)

2:20 SESSION SIX | UROTHELIAL CANCER | Co-Moderators: Robert Siemens & Michael Leveridge

2:22 Liquid Biopsy for Bladder Cancer Prognosis | Peter Black, MD 2:34 Impact of Urinary Marker Testing in Bladder Cancer | Badrinath Konety, MD 2:46 Clinical Implications of Mutational Profi ling of Invasive Bladder Cancer | Seth Lerner, MD 2:58 Should Variant Histology Change Management of Bladder Cancer? | Ashish Kamat, MD 3:10 DISCUSSION (10 mins)

3:20 SESSION SEVEN | ADVANCED PROSTATE CANCER | Moderator: Marcelo Bendhack

3:22 Medical Tourism in Urologic Oncology: Korean Perspective | Ji Youl Lee, MD 3:34 PSMA in the Management of Patients with Biochemical Failure | Shrawan Singh, MD 3:46 Chemotherapy and Radium for CRP - Role in the Era of ARTs | Peter Black, MD 3:58 How To Reduce Errors in Scientifi c Research | Laurence Klotz, MD 4:15 DISCUSSION (10 mins)

4:25 ADJOURN

October 4, 2018

Seoul D

ragon City

Cheongpa-ro 20 G

il 95 Yongsan-guS

eoul, South K

orea, 04347

세계

비뇨

기종

양 학

회

WUOF 세계 비뇨기종양 학회2018 World Urological

Oncology Federation

August 29/18

This meeting has been made possible by funding from our exhibitors and sponsors:

DRAFTFACULTY & PARTICIPANTS:

AustraliaProfessor Damien M Bolton, MD, PhD, BA, MBBS, FRCS, FRACSClinical Professor of SurgeryUniversity of MelbourneOlivia Newton-John Cancer andWellness CentreAustin Hospital, Melbourne

Shomik Sengupta, MBBS, MS, MD, FRACSGeneral, Oncology & Minimally Invasive Urologic SurgeonProfessor of Surgery, Eastern Health Clinical School, Monash UniversityLeader, Genitourinary Oncology Special Advisory Group, USANZGlen Waverly, Victoria

BrasilProf. Dr. Marcelo L. BendhackProfessor de Urologia HCV- UP Presidente Sociedade Latino Americana de Uro-Oncologia UROLAClinica de Uro-Oncologia do Brasil Ltda.São Paulo, Brasil

CanadaPeter Black, MD, FACS, FRCSCKhosrowshahi Family ChairProfessor, UBCDepartment of Urologic SciencesSenior Research ScientistVancouver Prostate Centre

Neil Fleshner, MD, MPH, FRCSCProfessor of SurgeryMartin Barkin Chair of Urology,University of TorontoHead, Division of Urology,University Health NetworkLove Chair in Prostate Cancer PreventionPrincess Margaret Hospital

Yves Fradet MD, CSPQ UrologyProfessor of Urology Université Laval QuébecHead, UrologyHead, Uro-oncology laboratoryCHU de Québec-Université Laval

Laurence Klotz, MD, CMProfessor of Surgery, University of TorontoChairman, WUOFChairman, CURCAssociate Editor, Journal of UrologyDivision of UrologySunnybrook Health Sciences Centre

Member SocietiesAsian-Pacifi c Society of Urologic Oncology (APSUO)Australian Urologic Oncology SectionBritish Association of Urologic Surgeons - Urologic Oncology Section (BAUS)Canadian Urological Oncology Group (CUOG)Chinese Urologic Oncology GroupEuropean Society of Urologic OncologyGeorgian Association of Oncological Urology (GAOU)German Society of Urological OncologyIndian Urological SocietyIsraeli Society of Urologic OncologyItalian Society of Urologic OncologyJapanese Society of Urological OncologyKorean Urological Oncology SocietyLatin American Society of Urologic OncologyMexican Society of Uro-Oncology Philippines Society of Urological Oncology (PSUO)Peruvian Association for the Study of Urological Cancer (APECU)Portuguese Genitourinary Uro-Oncological GroupSociety of Urologic Oncology (North America) (SUO)Turkish Urologic Oncology Society

With appreciation

SILVER sponsor

PLATINUM sponsor

INTERNATIONAL ISSUES IN UROLOGIC ONCOLOGY

October 4, 2018Seoul Dragon CityCheongpa-ro 20 Gil 95 Yongsan-guSeoul, South Korea, 04347

세계 비뇨기종양 학회

WUOF 세계 비뇨기종양 학회2018 World Urological

Oncology Federation

Michael Leveridge, MD FRSCSAssociate ProfessorDepartments of Urology & OncologyQueen’s UniversityKingston ON Canada

Jehonathan H. Pinthus, MD, PhDAssociate ProfessorUrologic OncologyDepartment of SurgeryMcMaster University

D. Robert Siemens, MDProfessor and ChairDepartment of UrologyQueen’s UniversityKingston, Ontario

FranceDr Guillaume Ploussard, MH, PhDInstitut Universitaire du Cancer Toulouse - Oncopole / Saint Jean Languedoc HospitalChairman, EAU-YAU Prostate CancerWorking Party

Rafael Sanchez Salas, MDAttending Surgeon, Department of UrologyL’Institut Mutualiste MontsourisParis, France

GermanyProfessor Dr. Peter HammererChairman Department Urology and UrooncologyAcademic Hospital BraunschweigSalzdahlumer Str. 90

Markus Grafen, MDProfessor of UrologyHead, Martini-Klinik Prostate Cancer CenterHamburg, Germany

Derya Tilki, MDProfessor of UrologyMartini-Klinik Prostate Cancer Centerand Department of UrologyUniversity Hospital Hamburg-EppendorfHamburg, Germany

IndiaS.K. Singh M.S, M.Ch, FAMSProfessor of Urology,Post Graduate Institute of Medical Education & Research, Chandigarh, India

Dr Makarand KhochikarMS DNB (Urol) Dip Urol (London) FRCS (Urol) FEBUChief Uro-oncologist Siddhi Vinayak Ganapati Cancer Hospital, Miraj (India)President Urological Society of India -West ZoneBoard of Directors SIU

IndiaDr. S.K Singh M.S, M.Ch, FAMSProfessor of UrologyPost Graduate Institute of Medical Education & ResearchChandigarh-160012, India

IsraelOfer YossepowitchProfessor of urologyChair, Department of urologyTel Aviv Sourasky Medical CenterTel Aviv, Israel

ItalyAlessandro Volpe, MDAssociate Professor of UrologyUniversity of Eastern Piedmont Maggiore

JapanShin Egawa, MDProfessor and Chairman,Department of Urology,Jikei University School of Medicine,Tokyo

KoreaHanjong Ahn, MD, PhDProfessor, Department of UrologyUniversity of Ulsan,Asan Medical CenterSeoul, Korea

Sung Kyu Hong, MD, PhDProfessorDepartment of UrologySeoul National University College of MedicineSeoul National University Bundang Hospital

Ji Youl Lee, MDProfessor & Director, Department of Urology, Seoul St. Mary’s HospitalDirector of Robotic Surgery Center, Seoul St. Mary’s HospitalVice-President of Research, Comprehensive Cancer Hospital, Seoul St. Mary’s HospitalDirector of Catholic Cancer Research InstitutePresident of Korea Prostate BankDirector of Catholic Prostate Institute

MexicoArturo Mendoza-Valdés, MDUROLOGOHospital Médica SurPuente de Piedra 150 T2-625Col. Toriello GuerraTlalpan 14050México DF, MEXICO

SwitzerlandFranz Recker, MDSenior ConsultantDept. of Urology and Prostate CenterCantonal hospital AarauSwitzerland

The NetherlandsPeter Mulders, MD, PhDProfessor and ChairmanDepartment of UrologyRadboud University Medical CentreNijmegen

Professor Dr Jack A SchalkenProfessor Experimental UrologyResearch Director UrologyRadboud UniversityNijmegen, Netherlands

United States of AmericaMatthew R. Cooperberg, MD, MPHAssociate Chair for Clinical ResearchAssociate Professor, Departments of Urology, Epidemiology & BiostatisticsHelen Diller Family Chair in UrologyUniversity of California, San Francisco

E. David Crawford, MDProfessor of Surgery/Urology/Radiation OncologyE. David Crawford Distinguished Endowed Chair in Urology Head Urologic OncologyUniversity of Colorado, Denver

Marc Dall’Era, MD

Professor and Vice ChairDepartment of UrologyUniversity of California, Davis

John W. Davis, MDProfessor of UrologyDirector, Urosurgical Prostate ProgramMD Anderson Cancer CenterHouston, Texas

Robert C. Flanigan, MD, FACSProfessor, Department of UrologyLoyola University Health SystemPresident of the American Urological Association

Ashish M. Kamat, MD, MBBSProfessor of Urologic Oncology (Surgery)Wayne B. Duddlesten Professor of Cancer ResearchAssociate Cancer Center Director, RFHNH, MumbaiThe University of Texas, MD Anderson Cancer Center

Seth P. Lerner, MD, FACS Professor, Scott Department of UrologyBeth and Dave Swalm Chair in Urologic OncologyDirector of Urologic OncologyDirector of the Multidisciplinary Bladder Cancer ProgramFaculty Group Practice Medical DirectorCo-Editor in Chief Bladder CancerBaylor College of Medicine Medical CenterHouston, Texas

Art R. Rastinehad D.O.Associate Professor of UrologyRadiology Director of Focal Therapyand Interventional Urologic OncologyIcahn School of Medicine at Mount SinaiNew York, NY

Martin Tenniswood, PhdChief Scientific OfficermiR Scientific, LLCRensselaer, New York

Robert E. Reiter, M.D., M.B.A.Bing Professor in Prostate CancerChief, Division of Urologic OncologyDirector, Prostate Cancer ProgramDepartment of UrologyDavid Geffen School of Medicine at UCLAInstitute of Urologic Oncology

The Korean Prostate Society

GOLD sponsor