Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4....

21
Insulin Signaling Pathway Boyle – Metabolic Brain Disorders IRS-1

Transcript of Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4....

Page 1: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt

Insulin Signaling PathwayBoyle – Metabolic Brain Disorders

IRS-1

Page 2: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 3: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 4: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 5: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 6: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 7: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 8: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 9: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 10: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 11: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 12: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 13: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 14: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 15: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 16: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 17: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 18: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 19: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt

Akt is involved in so many critical

functions.

Page 20: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt
Page 21: Insulin Signaling Pathway-part1pages.ucsd.edu/~mboyle//COGS163/pdf-files/05-COGS163... · 2020. 4. 18. · Insulin Signaling Pathway. Boyle – Metabolic Brain Disorders. IRS-1. Akt

Complexity of the insulin signaling pathway

Complexity of the insulin signaling pathway

insulin receptor and signaling - UCSD Cognitive Sciencemboyle/COGS163/pdf-files...insulin Tyrosine kinase domain Insulin insulin receptor signaling cascade Phosphorylation of docking

insulin receptor and signaling - UCSD Cognitive Sciencemboyle/COGS163/pdf-files...insulin Tyrosine kinase domain Insulin insulin receptor signaling cascade Phosphorylation of docking

The Adenosine Insulin Signaling Axis in the Fetoplacental ...cdn.intechopen.com/...insulin_signaling_axis...in_gestational_diabetes.pdf · Chapter 4 The Adenosine–Insulin Signaling

The Adenosine Insulin Signaling Axis in the Fetoplacental ...cdn.intechopen.com/...insulin_signaling_axis...in_gestational_diabetes.pdf · Chapter 4 The Adenosine–Insulin Signaling

Insulin Receptor Signaling in Normal and Insulin …cshperspectives.cshlp.org › content › 6 › 1 › a009191.full.pdfInsulin Receptor Signaling in Normal and Insulin-Resistant

Insulin Receptor Signaling in Normal and Insulin …cshperspectives.cshlp.org › content › 6 › 1 › a009191.full.pdfInsulin Receptor Signaling in Normal and Insulin-Resistant

Insulin Signaling in Osteoblasts Integrates Bone ...2000) and PTP1B, which dephosphorylates the insulin receptor, is a major regulator of insulin signaling in hepatocytes and myo-

Insulin Signaling in Osteoblasts Integrates Bone ...2000) and PTP1B, which dephosphorylates the insulin receptor, is a major regulator of insulin signaling in hepatocytes and myo-

Insulin signaling pathways in Age-related locomotor impairment

Insulin signaling pathways in Age-related locomotor impairment

Insulin signaling

Insulin signaling

Increased insulin signaling in fat body ofarizona.openrepository.com/arizona/bitstream/10150/229795/5/azu... · Increased insulin signaling in fat body of Aedes aegypti mosquitoes

Increased insulin signaling in fat body ofarizona.openrepository.com/arizona/bitstream/10150/229795/5/azu... · Increased insulin signaling in fat body of Aedes aegypti mosquitoes

Insulin signaling dynamics in human adipocytesliu.diva-portal.org/smash/get/diva2:698675/FULLTEXT01.pdf · Insulin signaling in type 2 diabetes – experimental and modeling analyses

Insulin signaling dynamics in human adipocytesliu.diva-portal.org/smash/get/diva2:698675/FULLTEXT01.pdf · Insulin signaling in type 2 diabetes – experimental and modeling analyses

Insulin signaling, resistance, and metabolic syndrome: insights … · Insulin signaling, resistance, and metabolic syndrome: insights from mouse models into disease mechanisms Shaodong

Insulin signaling, resistance, and metabolic syndrome: insights … · Insulin signaling, resistance, and metabolic syndrome: insights from mouse models into disease mechanisms Shaodong

Ch. 15 The Insulin Signaling Network and Insulin Action 2004. 6. 22.

Ch. 15 The Insulin Signaling Network and Insulin Action 2004. 6. 22.

Honors - Cells, insulin, signaling and membranes 1213

Honors - Cells, insulin, signaling and membranes 1213

Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin ... · Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes Amar

Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin ... · Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes Amar

170 insulin signaling & vldl overproduction

170 insulin signaling & vldl overproduction

Differential insulin and steroidogenic signaling in insulin resistant … · 2019-08-13 · 1 Title Page Differential insulin and steroidogenic signaling in insulin resistant and

Differential insulin and steroidogenic signaling in insulin resistant … · 2019-08-13 · 1 Title Page Differential insulin and steroidogenic signaling in insulin resistant and

Regulation of hepatic insulin signaling and glucose homeostasis … · Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2 Gulibositan Ajia,1,

Regulation of hepatic insulin signaling and glucose homeostasis … · Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2 Gulibositan Ajia,1,

The Hepatitis C Virus Modulates Insulin Signaling …...The Hepatitis C Virus Modulates Insulin Signaling Pathway In VitroPromoting Insulin Resistance Jose´ A. del Campo*, Marta Garcı´a-Valdecasas,

The Hepatitis C Virus Modulates Insulin Signaling …...The Hepatitis C Virus Modulates Insulin Signaling Pathway In VitroPromoting Insulin Resistance Jose´ A. del Campo*, Marta Garcı´a-Valdecasas,

Insulin-like growth factor receptor signaling in ...

Insulin-like growth factor receptor signaling in ...

The insulin receptor: structure, function, and signalingmboyle/COGS163/pdf-files/W2-AR-The insulin... · The insulin receptor: structure, function, ... The insulin receptor: structure,

The insulin receptor: structure, function, and signalingmboyle/COGS163/pdf-files/W2-AR-The insulin... · The insulin receptor: structure, function, ... The insulin receptor: structure,

OXIDATIVE STRESS, INSULIN SIGNALING AND DIABETES (1).pdf

OXIDATIVE STRESS, INSULIN SIGNALING AND DIABETES (1).pdf