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Centre Grant (CG) August 2016 Grant Call

Grant Application Form

<Title of the Centre Grant Programme>

Submitted By:

Institution(s)/Healthcare Cluster(s)

Closing Date: 25 October 2016, 5pm

SUBMISSION DETAILSThe submission must comprise the soft copy and the endorsed original hardcopy application.

Softcopy Details One softcopy submission, without signatures, is required. Please use the latest version of NMRC

Centre Grant Application Form (downloadable from http://www.nmrc.gov.sg/content/nmrc_internet/home/top_nav/download.html ) and name the document in the following format:

CGAug16_ [Main/Collaborative (use 1 to indicate if the proposal is for application under main pot or collaborative pot)]_(Name of Institution(s)). Example: CGAug16_Main_NCIS, CGAug16_Collaborative_SGH NDC

Softcopy Centre Grant application form must be saved as a single Microsoft Word document. Please adhere to the specified number of pages where applicable. The softcopy should not contain blank or irrelevant pages.

Hardcopy Details One hardcopy submission, with the signature of the Research Director and endorsement by the

Institutions’/Healthcare Clusters’ Heads for the host institution(s)1, is required. Please use the latest version of NMRC Centre Grant Application Form August 2016 Grant Call.

Submission to NMRC Please submit the softcopy to Ms Rane Tan, via [email protected]; and hardcopy via the

following address:

(Attn: Ms Rane Tan)Centre Grant ProgrammeNational Medical Research CouncilCollege of Medicine Building, 16, College RoadSingapore 169854

The deadline for soft and hardcopy submission is 25 October 2016 at 5pm.

The following will be rejected:o Incomplete applications e.g. softcopy submission only, missing documents such as signatures;

sections left blank, missing CVs, etc.o Outdated application form

No late or submission or revision to the submitted application will be entertained after the closing date.

For further enquiries, you may contact Ms. Rane Tan at [email protected]

1Definition of Host Institution: The body or institution or administering organization named in the Letter of Award as the “Host Institution” is the body responsible for undertaking and managing the Research and administering the Funding.

mailto:[email protected]

http://www.nmrc.gov.sg/content/nmrc_internet/home/top_nav/download.html

This document contains 7 sections.Please use Arial font, size 11 pt and single spacing for all text.

SECTION DESCRIPTION

1 Application Category

2 Focused Research Areas

3 Overall Research Strategy Plans

4 Research Themes

5 Budgets

6 Governance Structure

7 Expected Research Outcomes

8 Signatories

Annexes A1, A2, A3, A4, A5 etc – details of existing projects

Annexes B1, B2, B3, B4, B5 etc – biographical sketch

Annex C: Details of Existing PI/Co-I/Post-doc Fellow

Annex D: KPI Definition – for reference

Purpose of the Centre Grant Funding Opportunity

The objective of the Centre Grant is to provide funding support to the Public Healthcare entities to build up their core research capabilities in terms of common research platforms, shared resources (e.g. equipment) and core manpower to enhance their collaborative and transdisciplinary research productivity in achieving progress towards the RIE2020 goals of healthcare research (i.e. translational & clinical research). It is to capitalize on the institutional research capabilities, and aid in the development of shared resources that can support the institution’s/healthcare cluster’s or institutions’/healthcare clusters’ research in a focused area. The Centre Grant encourages collaboration and coordination of research efforts within the institution/cluster or among the institutions/clusters focusing in the same area of research to disseminate research findings for the benefits of the community. The Centre Grant should not be used to establish independent shared resources that duplicate existing institutionally-managed resources if the latter provide cost-effective, accessible and quality service.

Proposals are encouraged to address at least one of the RIE2020-prioritised therapeutic areas of research i.e. (i) Cancers, (ii) Cardiovascular diseases, (iii) Diabetes mellitus and related metabolic/endocrine disorders, (iv) Infectious diseases and (v) Neurological and sense disorders although other domain areas will be considered. With increasing focus to ensure that research outcomes can be translated into actual healthcare applications or public health policies to bring about greater impact and benefits to the healthcare system/population, it is important that the proposal address either (i) Translational medicine & implementation science research, (ii) Health System Research or (iii) Primary care research, associated with strategies for prevention and chronic disease management.

Based on the focus areas of research, the applicant entities will have to detail how the CG will be used to develop an overall programmatic structure within the institution/cluster or across partnering institutions/clusters to provide a unity of purpose, a centralized platform for sharing resources, and a management structure necessary to achieve progress towards the institution’s/cluster’s or partnering institutions’/clusters’ research agendas. The plans should also include a process for integrating education and training of healthcare professionals (or biomedical researchers, where relevant) into the programmatic research efforts.

Application for Centre Grant (CG)

All information is treated with confidence. The information is furnished to National Medical Research Council with the understanding that it shall be used or disclosed for evaluation, reference and reporting purposes. If your application is not successful, this form will be destroyed after the retention period deemed as appropriate by the Council.

1. APPLICATION CATEGORY (Please tick one accordingly)

Main Pot – Tier 1Funding Quantum: $8 million to $20 million over 4 years

Main Pot – Tier 2Funding Quantum: $5 million to $8 million over 4 years

Collaborative PotFunding Quantum: $3 million to $8 million over 4 years

2. FOCUSED RESARCH AREAS

2.1. Specialty Areas of ResearchPlease tick one of the following areas to indicate the focused research area of this application.

Cancers Infectious Diseases

Cardiovascular Diseases Neurological and Sense Disorders

Diabetes Mellitus and related Metabolic/Endocrine disorders

Others, please specify______________________

2.2. Translational FocusPlease tick one or more of the following population-based areas which the application is also focusing on.

Translational Medicine & Implementation Science

Health Systems Research

Primary Care Research, linked to strategies for preventionand chronic disease management

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3. OVERALL RESEARCH STRATEGY PLANS

3.1. BackgroundProvide a short history and overview of the current research funding structure support of the institution/cluster or partnering institutions/clusters and the facilities and capabilities that have been developed over the years in the associated research focused areas. Briefly describe the important research accomplishments that the institution(s)/cluster(s) have attained in the past in the relevant focused areas of research. (Please limit to 3 pages)

3.2. RIE2015 Centre Grant (for completion by proposals involving a current RIE2015 CG-awarded institution)Please describe what have been achieved under the RIE2015 Centre Grant in accordance to the proposed research strategy plans. Where applicable, please state if the concerns, or recommendations provided by the 2CG-SAB during the mid-term review has been followed up accordingly. (Please limit to 2 pages)

3.3. RIE2020 Research Strategy Plans In this section, each proposal should:

(Please limit to 5 pages)

a. describe the research agendas of the institution(s)/cluster(s) through the Centre Grant and please define the areas of research focus.

b. describe the challenges/gaps currently faced by the institution(s)/cluster(s) that can be filled through the Centre Grant Funding Support

c. describe how the Centre Grant can help to support the research of the institution(s)/cluster(s) through:

- centralized shared resources that provide access to technologies, services, and scientific consultation that enhance scientific interaction and productivity;

- strategic planning and evaluation that further the research agenda of the institution(s)/cluster(s);

- developmental funding that allows the institution(s)/cluster(s) to pursue newly identified priorities, strengthen weaker scientific areas, and explore new collaboration and technologies;

- centralized administration of resources and services, fiscal management and other supportive activities;

- capacity development for both research staff and research support staff, future clinical and scientific leaders in medical or biomedical research

d. what are the achievable outcomes the institution(s)/cluster(s) aim to achieve through the proposed research strategy plans, particularly healthcare-specific outcomes?

e. what are the short-term (within 4 years) and long-term goals that the institution(s)/cluster(s) hopes to achieve from its research strategy

f. in what way will the research strategies, aims and plans help the institution(s)/cluster(s) in becoming an internationally competitive. Name at least one Centre you can be benchmarked with.

3.4. Merits of Collaboration 2 The CG-SAB is the Centre Grant Scientific Advisory Board which was set up to conduct a mid-term review on the progress of the RIE2015 CG-awarded institutions in Sep 2015. It comprised 10 international members with expertise in different disease domains.

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(for completion by applications under the collaborative pot)Please describe the merits of collaboration between the partnering institutions/clusters and the greater potential or synergy that the collaboration can lead to as compared to individual CG support for each entity? How will the partnering entities work together? (Please limit to 3 pages)

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4. RESEARCH THEMESThis section details the research themes which the focused areas of research are organized into for the identification and planning of the core research capabilities to be built under the Centre Grant. . Please state up to 8 research themes that are pertinent to the research focus of the institution/cluster or partnering institutions/clusters. (Please limit each theme to 3 pages which does not include the Annexes)

4.1. Research Theme 1a. Title of Research Themeb. Specific Aims of Research Themec. Clinical and Healthcare Significanced. Team Leader(s) and Key Opinion Leader(s) and Member(s) and their roles

Attach the following annexes as supporting information to the research theme 1: Annex A1 – Details of existing projects e.g. title, project PI, quantum funded, funding

agency, start and end dates, short description/abstract of projects Annex B1 – Biographical Sketch of the Team Leader(s), Key Opinion Leader(s) and

Key Member(s).




Key Member(s).




Key Member(s).




Key Member(s).


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Key Member(s).




Key Member(s).




Key Member(s).




Key Member(s).

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5. BUDGETS There are four fundable components under the Centre Grant. The applicants are advised to prepare the budget carefully under each category and provide the justifications for all components.

For applicants applying under the collaborative pot involving more than one institution/cluster, please replicate the budget sections for 5.1 Research Personnel Core, 5.2 Facility Core, 5.3 Administrative Core and 5.4 Seed/Bridging Fund Core per institution/cluster.

5.1. Research Personnel CoreThis component will capture the amount of the Centre Grant budget that is attributed to supporting the salaries of research-related personnel, i.e

research-active Scientists (e.g. Clinician-Scientists, Clinician Investigators, allied Health Professionals) who have the ability to attain peer-reviewed grants for the institution(s); and

key personnel operating the centralized shared resources or services, including facility cores leaders, research support staff (e.g. Research Assistant, Research Technologist)

Justifications have to be provided for each manpower support. Up to 50% of the overall CG budget can be budgeted for the Research Personnel Core category. Strong and compelling justifications have to be provided if it exceeds 50% of the overall CG budget. It will be subject to the stringent assessment by the evaluation panel.

a. Budget

ManpowerState whether they are existing personnel in the institution(s)/cluster(s) or new staff to be recruited. Please use salary scales provided by the Institution(s)/cluster(s) as a reference. The cost should include annual increments, National Service increment, staff welfare, medical and other related benefits as per the Human Resource policies of your institution(s)/cluster(s). Please note that the NMRC’s annual salary cap by Clinician’s Clinical Grade (as below) will be referenced as a guide to assess the reasonableness of the requested CG budget for the support of any Clinician Scientist(s)/Investigator(s).

Source: http://www.nmrc.gov.sg/content/nmrc_internet/home/grant-navigation/talent-development/clinician scientist---clinician-investigator-salary-support-prog.html

Note: For any existing PIs/co-Is/Post-doc fellows who are budgeted, you are required to provide their additional information at Annex C. The completion of the information is mandatory.

Component: Research Personnel CoreCluster/Institution Name:

Staff Category Existing/New

No Remarks (FTE) Total cost

Principal Investigator (PI)Co-Investigator

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http://www.nmrc.gov.sg/content/nmrc_internet/home/grant-navigation/talent-development/clinician

(co-I)TechnologistResearch AssistantResearch OfficerResearch AssociateResearch NursePostdoctoral Fellow

Visiting ConsultantOthers: (please specify)

Total $0.00

b. Justifications

5.2. Facility CoresThis support the centralized shared research resources that are required to be developed within the institution/cluster or between the partnering institutions/cluster(s) to provide researchers access to equipment, technologies, services as well as expert consultation to fulfil the research objectives. The budget can be used to purchase equipment, provision of dedicated space for research operations, physical facilities, technology platforms, as well as other operating expenses necessary for the development and maintenance of core research capabilities. Applicants are to provide justifications for each facility core and advised to plan for 25%-30% of the overall CG budget for setting up the facility cores.

Replicate sections 5.2(a), 5.2(b) and 5.1(c) for each facility core, naming them in running number, i.e. Facility Core 1, Facility Core 2, Facility Core 3 etc. (Please limit 2 pages to each facility core.)

a. Details of the Facility Core 1

Title of Facility Core 1(Name of the Facility Core Leader)

Purpose of Facility Core 1 and its functions:

How it lead to synergy and cohesion between the research themes, groups and facilities?

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Any Sustainability Plans? Please provide the details

How it ensures the facility is accessible to the other partnering institutions/clusters.(to be completed by applicants under the collaborative pot involving more than one partnering cluster/institution)

b. Budget

EquipmentPlease budget for the equipment items that have to be purchased for the setting up the facility core. . For equipment costing more than $100,000 each, please indicate the estimated utilization of the equipment (e.g. 70% usage throughout the project period; only 85% usage in the 2nd year for analysis purpose, etc).

Title of the Facility Core 1 :

Qty Equipment

Estimated Utilization Rate for Equipment more than $100,000 (to be justified)

Unit Cost Sub- Total

Total $0.00

Other Operating Expenses (OOE)This category covers other expenses directly related to the setting up of the facility core. All items budgeted must be aimed at fulfilling the research agenda of the institution(s)/cluster(s). Conference travel will be funded only if an article is presented. The budget for conference travel will be capped at $6,000 per person per trip. NMRC’s support must be acknowledged for any presentation made or article being published.

Title of the Facility Core 1:

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Item Item Description Cost

Materials & Consumables

Overseas Travel

Others:(please specify)

Total $0.00

Grand Total for Specific Facility Core: SGD $0.00

c. Justifications for Facility CoreBased on what you have budgeted for section 5.2b, please provide the justifications in the following.

Equipment

Other Operating ExpensesMaterials & Consumables

Overseas Travel

Others e.g. Singapore Clinical Research Institutes (SCRI) cost

5.3. Administrative CoreThis cover the costs necessary for the central administration of resources and services required for the institution(s)’/cluster(s)’ research activities, fiscal management of the centre grant and reporting

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activities. It can also be used for the appointment of key administrative personnel, including senior leadership to oversee the administration of the centre grant, covering cost for training/education purposes and development of mentorship programmes for grooming talent and expertise in clinical research. Applicants are to provide justifications and advised to plan for 10%-15% of the overall CG budget for this purpose

a. Details of the Administrative CorePlease provide details of how the administrative core is structured to manage the administration of the centre grant. Describe the existing committees, including senior leaderships that will be involved to coordinate research efforts within the institution(s) through the support of the centre grant.

b. Budgets

Administrative Manpower

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Please budget for all the manpower required, full-time and part-time inclusive. Please state if they are existing personnel of the institution(s)/cluster(s) or new staff to be recruited. Please use salary scales provided by the Institution(s)/Cluster(s) or Hospital Administration as a reference. The cost should include annual increments, National Service increment, staff welfare, medical and other related benefits as per the Human Resource policies of your institution(s)/cluster(s).

Staff Category Existing/New

No Remarks (FTE) Total cost

Centre Grant Director

Administrative Manager

e.g. Support Staff




Total $0.00

Education and Training BudgetPlease budget the cost of training and education for the administrative staff as well as the budget the cost associated with the development of mentorship programmes to train and build expertise in clinical research.

Title of the Training/Education

courses or Mentorship Programme

Purpose Amount

Total $0.00

Grand Total for Administrative Core: SGD $0.00

c. Justifications for Administrative Core

Manpower and Education & Training

5.4. Seed Funding Programme Core6

This component allows the award of (i) pilot grants, each capped at $50,000 to young clinician investigators to generate the necessary preliminary data to apply for higher-level national grants or (ii) bridging grant for a maximum period of 1 year to sustain key research manpower from grants which have already ceased. Applicants are to provide justifications and can use up to 10% of the overall CG budget for this purpose

a. Pilot GrantsReplicate the table of details for each seed funding programme, in running number, i.e Seed Funding Programme 1, Seed Funding Programme 2, Seed Funding Programme 3, Seed Funding Programme 4 etc.(Limit one page to one seed funding programme)

Title of Seed Funding Programme 1 (Cluster/Institution Name)

Purpose

Total amount allocated for this programme

Expected no. of pilot grants to be awarded. Also, specify the funding quantum and duration.

b. Bridging Grants

Manpower No Remark (FTE)

Total cost State Supporting Period(Start Date to End Date)

Others: (please specify)

Total $0.00

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5.5. Overall Summary of Budgets (for the whole proposal)

S/N Category Total Budget (S$)

1 Research Personnel Core

2 Facility Core 1 (replicate section for each facility core)

Sub-category Budget (S$)

Equipment

Other Operating Expenses

Facility Core 2 (replicate section for each facility core)


Equipment

Other Operating Expenses

3 Administrative Core


Manpower

Education/Training and Development

4 Seed Funding Programme Core


Pilot Grants

Bridging Grants

Total (S$)

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Admin assistant

Admin Mgr

Bridging Grant

Bridging Grant

Title 5

Title 3

Title 1

Facility Core 4

Facility Core 1

Training prog 1

SUPPORTED CORES

Centre Grant Programme Title

Administrative Cores Manpower (state the designation only. E.g. administrative manager, project manager etc.) Training Development

Research Personnel/Facility CoresResearch Scientists

Research Support Staff

Facility Core 2

Facility Core 3

Facility Core 5

Seed Funding Programmes/

Bridging Grant Core (state the seed funding

programmes title)

Proj Mgr

Training prog 2

Research Theme 4Research Theme 1 Research Theme 2 Research Theme 3 Research Theme 5

Theme Leader(s) and Member(s) (State names and

designations)


designations)


designations)


designations)


designations)

6. GOVERNANCE STRUCTURE Please provide a graphical overview of the research strategy plans showing how the proposed research core capabilities can support research in the institution(s)/cluster(s). You should show the links between the research themes and the research cores. You should demonstrate that there is synergy and cohesion between the themes and the research cores and explain how they can complement each other in achieving the desired research outcomes.

Example

Figure 1: Governance Structure.

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7. EXPECTED RESEARCH OUTCOMES Please indicate your realistic expectations on the outcomes of the Centre Grant Programmes by providing the projected number/value of each listed KPI that you will aim to achieve after end of the 4 year funding, i.e. from start of FY2017 to end of FY2020. You should reference the definition of the KPIs at Annex D to submit the project value/number.

KPI Category S/N Performance IndicatorsProjected Number/

Value(FY17 to FY20)

Human Capital

1 No. of STAR awards

2 No. of CSA awards

3 No. of Transition awards

4 No. of Clinicians who graduated from Master/PhD programmes

5 No. of MD-PhD or PhD currently employed

6 No. of NMRC Fellowships

7 No. of PhD and Master Students trained and graduated

8 No. of PhDs and Masters who work in Singapore (i) upon graduation and (ii) 5 years after graduation

Intellectual Capital

9 No. of publications in top 10% journals by field

10 No. of technical disclosures

11 No. of patents granted

12 No. of Individuals (PI) holding peer-reviewed national/international-level grants

13 Total amount/quantum of competitive research grants as PI

Industry Relevance

14 Amount of Industry Funding/spending (cash)

15 Amount of Industry Spending (in-kind)

16 No. of licenses

17 Amount of licensing revenue

18 No. of spin-offs supported

19 No. of clinicians, faculty researchers and/or student exposed/participated in innovation & enterprise (I&E) activities

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KPI Category S/N Performance IndicatorsProjected Number/

Value(FY17 to FY20)

Healthcare Deliverables

20 No. of regulated Clinical Trials (registered under clinicaltrials@gov, HSA or equivalent agencies)

21 No. of subjects recruited for clinical trials (including overseas sites if the Singapore Investigator is the overall study PI)

22 No. of subjects recruited for cohort or other clinical studies

23 No. of citations in healthcare/health research studies arising from NMRC-supported centres/programmes/projects

24No. of Health Service Development Projects (HSDP) or documented quality improvement projects arising from previously NMRC-supported centres/programmes/projects

25No. of reports/presentations arising from NMRC-funded centres/programmes/projects that are made to policy-makers, health system managers, healthcare leadership etc.

26No. of NMRC-supported clinician scientists/investigators who progressed to take on leadership position (e.g. Head of Department, Div Chair etc)

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No. of NMRC-supported centres/programmes/projects with findings that result in new or changes in local or international clinical practices guidelines (e.g. CPG) and healthcare/health policies

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No.of electronic/online/non-traditional/technological tools developed from NMRC-supported centres/programmes/projects that lead to better information dissemination to doctors and patients

29No. of media reports and public education materials (e.g. Health Promotion Board booklet) arising from NMRC-supported centres/programmes/projects

30No. of outreach or community programmes developed due to the influence of NMRC-supported centres/programmes/projects (e.g. HPB campaigns, new screening programmes)

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No. of health economic (including cost-effectiveness and other health technology assessment applications) studies from NMRC-funded centres/programmes/projects that influenced health/healthcare policies or services.

32No. of life years saved arising from all services (new/improved), medical interventions or health policy implemented from NMRC-funded centres/programmes/projects

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8. SignatoriesIn signing the Grant Application, the institution(s)’/cluster(s)’ Head, Research Director and Centre Grant Key Leaders/Members UNDERTAKE, on any Grant Award, to:

Declare that all information is accurate and true. Declare that he/she is free from any financial conflicts of interest. Not send similar versions or part(s) of this proposal to other agencies for funding. Be actively engaged in the execution of the research plans and comply with al laws, rules and

regulations pertaining to safety, animal and human ethics, including the Singapore Good Clinical Practice guidelines

Ensure that National Medical Research Council (NMRC) funding is acknowledged in all publications and presentations.

Ensure that the requested equipment/resources are not funded by another agency or research proposal.

Ensure that there is a reasonable effort in accessing available equipment/resources within the host institution or elsewhere within Singapore.

Adhere to NMRC’s general guidelines on competitive funding and NMRC’s Terms and Conditions.

The undersigned agree to abide by the conditions governing the award of research grants set out by the National Medical Research Council (NMRC) of Singapore. Please add rows if necessary.

Institution/Cluster HeadName:Date:



Research DirectorName:Date:

Key Leader/MemberName:Date:





Endorsement by the Institution Head/Cluster Head

Name:

Designation:

Signature: Date:

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Annex A1

Research Theme 1: <Title>

Details of existing projects e.g. title, project PI, quantum funded, funding agency, start and end dates, short description/abstract of projects

Note: Please insert Annexes A2, A3, A4, A5, A6, A7, A8 (where relevant) accordingly to the Research Themes of Focus.

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Annex B1

Research Theme 1: <Title>

Biographical Sketch

(a) Team Leader(s) / Key Opinion Leader(s)Please use the format below to provide the required information on the Team Leader(s) and Key Leader(s) involved in Research Theme 1. Please indicate NA if the required information is not applicable. (Please limit to 3 pages per individual.)

Name Title NRIC/Passport No. Office Mailing Address Email Contact No. Current Position (Please provide full details, e.g. joint appointments; other academic appointments

including those outside Singapore: percentage of time spent in Singapore every year, if applicable)

Employment History Academic Qualifications (Indicate the degree’s title, year of award and name of the institution that

conferred the degree) Research Interests Publication in the last 5 years Patents held Scientific Awards Half page summary of research outcomes from all previous grants

(b) Key Member(s)Please use the format below to provide the required information on the Research Theme Member. Please indicate NA if the required information is not applicable. (Please limit to 2 page per member.)

Name Title NRIC/Passport No. Office Mailing Address Email Contact No. Current Position (Please provide full details, e.g. joint appointments; other academic appointments

including those outside Singapore: percentage of time spent in Singapore every year, if applicable) Employment History Academic Qualifications (Indicate the degree’s title, year of award and name of the institution that

conferred the degree) Research Interests Publications in the last 5 years Relevant Patents held Scientific awards Current and Previous Support from NMRC or other sources (Please also include proposals pending approval)

Note: Please insert Annexes B2, B3, B4, B5, B6, B7, B8 (where relevant) accordingly to the Research Themes of Focus.

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Annex CDetails of Existing PI/Co-I/Post-doc Fellow Supported under the Centre Grant

S/N Name of PI/Co-I/Post-doc Fellow

FTE Supported

Any grants held as PI in the past 5 years? Yes/NoIf Yes, please provide the details of the grants in the following If No, what is the role of the

PI/co-I/Post-doc Fellow in the CG programme and why it should be supported?

1. Title of Grant Funding Agency

Amount of Funding Start to End Date

2. Title of Grant Funding Agency

Amount of Funding Start to End Date

Please insert rows accordingly to enter the necessary details for each existing PI/co-I/post-doc fellow the institution has budgeted for support in the CG proposal.

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Annex D

KPI Definition

S/N

Indicators Definition

Human Capital KPIs1 Number of STAR awards This measures the number of NMRC STAR awardees in your institution. The award

should be active as of the reporting period.

2 Number of CSA awards This is to measure the number of NMRC CSA awardees in your institution. The award should be active as of the reporting period.

3 Number of Transition awards This is to measure the number of NMRC TA awardees in your institution. The award should be active as of the reporting period.

4 Number of Clinicians who graduated with Master/MD/PhD programmes

This measures the number of Clinicians employed by your institutions have graduated with the indicated-qualification programmes. Please note that Master of Medicine will not be included. The conferment date should be within the reporting period.

5 Number of MD-PhD or PhD currently employed

This measures the number of MD-PhD or PhD currently employed by your institution. The personnel should remain employed as of the reporting period.

6 Number of NMRC Fellowships This measures the number of NMRC fellowship awardees in your institution. The date of the letter of award should be within the reporting period.

7 Number of PhD and Master students trained and/or graduated

This measures the number of PhD and Master students whose supervisors are employed by your institution. You could include those who have graduated and also still in training. The training should be ongoing as of the reporting period or the conferment date should be within the reporting period.

8 Number of PhDs and Masters who work in Singapore (i) upon graduation and (ii) 5 years after graduation

This measures the number of graduates who are working in your institution (i) upon graduation and (ii) within 5 years after graduation, tracked by PhDs and Masters. The graduates should have worked for 5 years or more in your institution as of the reporting period.

9 Number of NMRC-supported clinician scientists/ investigators who progressed to take on leadership position (e.g., Heads of Department, Div Chair, etc.)

This measures the number of both NMRC-supported Clinician-Scientists (Cses) and Clinician Investigators (Cis) through NMRC Human Capital Award or Talent Development Programmes who have progressed to take on leadership positions your institution. (e.g. Heads of Department, Div Chair). The date of progression should be within the reporting period.

Intellectual Capital10 Number of publications in top 10%

journal by fieldThis measures the number of publications with acknowledgement of your institution that are published in the top 10% of S&T journals in the field as tracked in the Thomson Reuters Joint Citation Reports or other publication sites. The date of publication should be within the reporting period.

11 Number of technical disclosure This measures the number of technical disclosures submitted on related technology developments with at least one of the listed inventors being employed by your institution. The submission date of the technical disclosure should be within the reporting period.

12 Number of patents granted This measures the number of patents granted and at least one of the listed inventors or co-inventors is employed by your institution. The granted date should be within the reporting period.

13 Number of Individuals (PI) holding peer-reviewed national/international-level grants

This measures the number of personnel employed by your institution who have been awarded as PI or co-PI (exclude co-I and collaborator) for peer-reviewed national/international-level grants. The date of award should be within the reporting period.

14 Total amount/quantum of competitive research grants as PI -includes both direct and indirect costs

This measures the total amount of grant funding received by personnel employed by your institutions as Pis or co-Pis (exclude co-Is and collaborators). The date of award should be within the reporting period.

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S/N Indicators Definition

Industry Relevance15 Amount of Industry

Funding/spending (cash)This refers to the amount of cash funding that companies commit to spend in Singapore as a result of collaboration with personnel who is employed by your institution or the amount of cash funding received by your institution from private sector industry sources for projects whose PIs are employed by your institution. The investment by the companies should be reflected in the agreements signed between the companies and the relevant PIs of your institution. The date of agreement should be within the reporting period.

16 Amount of Industry Spending (in-kind)

This refers to the amount of in-kind investment that company commits to spend in Singapore as a result of collaboration with personnel who is employed by your institution. The investment by the companies should be reflected in the agreements signed between the companies and the relevant PIs of your institution. The date of agreement should be within the reporting period.

17 Number of Licenses This measures the number of intellectual properties which have been licensed out and where, at least one of the inventors/co-inventors is employed by your institution. The same licence should be counted only one regardless of the number of end-users as it is based from the same project idea. The date of licencing agreement contract should be within the reporting period.

18 Amount of licensing revenue This includes what your institution receives as (i) upfront/one-time payments; (ii) recurring revenue from royalty bearing IP licenses; (iii) licensing revenue from End User Licensing Agreement (EULA); and (iv) equity received in lieu of upfront/royalty payments (i.e. value of equity stake in spin-offs will be market to market until the sale of entire equity stake of the company). The date of licencing agreement contract should be within the reporting period.

19 Number of spin-offs supported This measures the number of spin-offs generated by personnel employed by your institutions that demonstrate successful market validation; the spin-offs must be launched on the back of an IP/technology. The start date of the spin-off should be within the reporting period.

20 Number of clinicians, faculty researchers and/or student exposed/participated in innovation & enterprise (I&E) activities

This measures the number of clinicians, researchers and/or students from your institution which participated/exposed to I&E activities organised by the National Health Innovation Centre (NHIC)- supported by NMRC. The date of the I&E activity should be within the reporting period.

Healthcare21 Number of registered clinical trials

initiated from previously NMRC-supported centres/programmes/projects (registered under Clinicaltrials@gov, HSA, or equivalent agencies)

This measures the number of new and existing clinical trials that were initiated by your institution and are the results of centres/programmes/projects supported by NMRC funding. These clinical trials must be registered with the Clinicaltrials@gove, HSA or equivalent agencies to be counted as the institutions' KPI achievement. The date of the registration should be within the reporting period.

22 Number of subjects recruited for clinical trials

This measures the number of subjects that have been recruited by your institution (as a recruitment site) for registered clinical trials. Subjects can be double counted if they are enrolled in different clinical trials. You should only include subjects whose consent is newly obtained during the reporting period.

23 Number of subjects recruited for cohort or other clinical studies (Clinical trials listed under S/N 22 should not be repeated here. However, if a subject had enrolled for both a clinical trial and cohort study, he/she may be counted under S/N 22 and S/N 23)

This measures the number of subjects that have been recruited by your institution (as a recruitment site) for other clinical or cohort studies except regulated clinical trials. Subjects can be double counted if they are enrolled in different clinical studies. Studies such as "case-review report type" or retrospective studies (with waiver of patients' consent) are not accepted. You should only include subjects whose consent is newly obtained during the reporting period.

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S/N Indicators Definition

24 Number of citations in healthcare/health research studies arising from NMRC-supported centres/programmes/projects

This measures the number of citations in other healthcare/health research studies from findings of previous NMRC-supported centres/programmes/projects in your institution. Examples, findings which are subsequently used in other research studies, commentaries, systematic reviews, review articles. The date of citation (as shown in the publications or documentation) should be within the reporting period.

25 Number of Health Service Development Projects (HSDP) or documented quality improvement projects arising from previously NMRC-supported centres/programmes/projects.

This measures the number of HSDP projects or documented quality improvement projects arising from studies previously supported by NMRC funding programmes in your institution. Example: HSR project to HSDP project. The date of the awarded projects should be within the reporting period.

26 Number of reports/presentations arising from NMRC-funded centres/programmes/projects that are made to policy-makers, health system managers, healthcare leadership etc.

This measures the number of reports/presentations arising from findings from previous NMRC-supported centres/programmes/projects in your institution that are made to healthcare leaders, policy makers, health system managers who have potential to make changes to the healthcare system through their scope of responsibilities. The date of the published reports/presentations made should be within the reporting period.

27 Number of NMRC-supported centres/programmes/projects with findings that result in new or changes in local or international clinical practice guidelines (e.g. CPG) and healthcare/health policies.

This measures the number of previously supported NMRC centres/programmes/projects in your institution that have resulted in the development of new or changes to either local or international clinical practice guidelines as well as healthcare/health policies. This includes implementation of any new or improved interventions or diagnostics (can be drugs and procedures) or services (e.g. new clinical service, shorter patient waiting time). Implementation at the institutional or national or international level will have to be indicated accordingly. The date of implementation should be within the reporting period.

28 Number of electronic/ online/ non-traditional/ technological tools developed from NMRC-supported centres/ programmes/ projects that lead to better information dissemination to doctors and patients

This measures the number of electronic/online/non-traditional/technological tools that have been developed in association to previous NMRC-funded research in your institution and have led to better information dissemination to the doctors and patients (e.g. registry databases, communication tools such as interactive videos for patients). The completed date of development should be within the reporting period.

29 Number of media reports and public education materials arising from NMRC-supported centres/programmes/projects

This measures the number of media reports and public education materials that were generated arising from findings of previous NMRC-supported centres/programmes/projects in your institution. Examples: Health Promotion Board Booklet. The date of publication of the reports and materials should be within the reporting period.

30 Number of outreach or community programmes developed due to the influence of NMRC-supported centres/ programmes/ projects

This measures the number of outreach or community programmes developed due to the influence of previous NMRC-funded research in your institution. Examples: HPB campaigns, new screening programmes. The event date(s) of the programmes should be within the reporting period.

31 Number of health economic (including cost-effectiveness and other health technology assessment applications) studies from NMRC-funded centres/programmes/projects that influenced health/healthcare policies or services.

This measures the number of health-economic related studies (including cost-effective and other health technology assessment applications) conducted on previously NMRC-funded research in your institution that have influenced health/healthcare policies or services. Studies must be submitted to the MOH forum (e.g. DMS-CMB meeting and/or MSM meetings or others) to have any impact. The completed date of health-economic analysis should be within the reporting period.

32 Number of life years saved arising from all services (new/improved, medical intervention or health policy implemented from NMRC-funded centres/programmes/projects

This measures the number of life years saved leading to a reduction in Disability Adjusted Life Years (DALYs) and/or an increase in Quality Adjusted Life Years (QALYs) from NMRC-funded centres/programmes/projects in your institution. Institutions must indicate the source of evidence accordingly to show evidence of the number of the life years reported. The date of the published source should be within the reporting period.

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Instructions to Completing the Centre Grant Web viewPlease note that the NMRC’s annual salary...

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Transcript of Instructions to Completing the Centre Grant Web viewPlease note that the NMRC’s annual salary...