Website: https://insilicodb.com

Facebook:https://www.facebook.com/Insilicodb

Twitter: @InSilicoDB

InSilicoDB the collaborative genomics hub

Makers of

InSilico Genomics S.A.

InSilicoDBGenome data: our very own “Google” medical map

2

The genome data represents a first step toward a high-definition medical map of every individual — a digitized human being. We are moving into the big data-per-individual era (with your very own “Google” medical map)

InSilicoDB

Navigating it could save your life

Should I have a regular melanoma screening?

3

Navigating your medical digital map it could save your life

How would that work? 1. you sequence your genome 2. a team of biologists analyses it 3. they discover you are at-risk for developing skin cancer 4. you start regularly visiting your dermatologist 5. she discovers a small tumor, and removes it before it kills you

Currently, for you and I, even if we sequenced our genomes, we don’t have access to our own private team of biologists. And since it's not affordable, or even possible, that we all go to visit every kind of doctor every month, we do nothing. And the unlucky among us that should get their skin checked… die

InSilicoDB

4

We need biologists to navigate our genomes

Biologists need to interact with data in collaboration with their colleagues, analysing them in multiple analysis tools using different formats

We really need to make it easy for biologists to help us navigate our medical map.

In order to analyse our genomes biologists need to interact with data in collaboration with their colleagues, analysing them in multiple analysis tools using different formats

InSilicoDB

but it’s impossible for them without programming skills

• Data is huge

• Data are scattered, not standardised

• The lack of organisation is a barrier to collaboration

5

But: • A genome is so massive that it could fill up an entire hard drive

• The data has to be moved around but it's scattered, and

• There are no standards

And biologists are not able to handle these data, basically because they don’t know how to program.

InSilicoDBInSilicoDB the collaborative genomics hub

6

7,4528,000

60

We built InSilico DB, a collaborative genomics hub that makes it possible for biologists to analyse genomics data without any programming skills. We created a hub where data is centralised, it flows in, is standardised, curated and then flows out to various analysis tools scientists use to interrogate and interpret the data.

InSilicoDB

7

All genome data is centralised on a secure cloud allowing easy collaboration

And interactive collaborative analysis of the data becomes possible, and fun!

InSilicoDB

8

And interactive analysis of the data becomes easy

And interactive collaborative analysis of the data becomes possible, and fun!

InSilicoDB

Biologists are now moving their research online, studying “digitized” humans

9

Our customers are now able to analyse genome data and are moving their work from the bench to the computer. It’s amazing how our product is actually transforming the way our customers work!

InSilicoDB

•

More than 15% monthly growth rate

User acquisition

0

2000

4000

6000

8000

3000 registered users

3 years - 3,000 usersno marketing efforts - word of mouth following

presentations and scientific publication

7,456 registered users

4 months - 4,400 usersmarketing efforts in social networks

targeting biologists

INSILICO DB TRACTION

Original expectation: 1,000 new users/month at €5/user

June €15/new user

July €10/new user

August €6/new user

September €3/new user

2012 2013 May 2015 Oct 2015

e-marketing campaign results

Last 30 days results: 1,190 new users at €2.3 / per user

INSILICO DB ACTIVITY

6 month period Number of Active Users* Number of Users uploading personal data

Number of Users that did an analysis

Jan-Jun 1,232 127 623Feb-Jul 2,156 187 904Mar-Aug 2,900 232 1,095Apr-Sep 3,650 269 1,294

0

1,000

2,000

3,000

4,000

0

70

140

210

280

0

325

650

975

1,300

page likes today15,188

Cost per User

2014

*Active User = Registered User who returns to our platform at least once over the last 6 months

10

We are getting significant traction, growing at 15% month/month to over 8,000 scientists , 400,000 genomes, 50 new discoveries in scientific publications

InSilicoDBBillions of people to get sequenced,

InSilico will put those genomes into the hands of those that can interpret them

11

InSilicoDB

In the next decade, as billions of us get sequenced, InSilico will put our genomes directly into the hands of these biologists who can use them to improve our health and lifestyle, for our own benefit, and under our own terms.

InSilicoDBCurrently raising a round to empower an agile and experienced team supported by product, market and business mentors

David Weiss, Founder & CEO

Bioengineer, PhD in bioinformatics ULB, did genomics research at Broad Institute and MIT.

Molecular Biologist, PhD in Bioinformatics from University of Manchester

Robin Duqué, Full Stack Dev.Master in BiotechnologyPreviously VP of engineering @ Sparkcentral, an SV startup that raised $18M

Main front-end developper2 years experience on InSilico DB

MD, dermatologist5 year experience in InSilico DB

James Cauwelier, Systems Architect

Jaro Vanderheijden, Web Developper

Industrial Engineer, founding team member with 5 year experience building InSilico DB. Previously, software engineer @ ING (banking)

Virginie de Schaetzen, Biocurator

Investment banker and Private Equity investor, Member of the Board of Ageas insurance group

PhD in Molecular BiologyExperience in R&D subsidy management

Lionel Perl, Chairman of the Board Andréa Goldsztein, Adm. Assistant

12

Alain Coletta, Founder & Exec. director

Our team:Alain and I were working for years as data scientists helping biologists use genome data.James fresh from building the infrastructure from SparkCentral jumped in to build the platformFounders of largest Belgian internet exit Ogone are full in

We are currently raising a round to:

• Further Increase platform ease-of-use and reliability • grow the community of biologists • add more analysis tools and data • invite individuals to participate through their genomes