Inside Cover: Disruption of Transcriptionally Active Stat3 Dimers with Non-phosphorylated, Salicylic...
2
The inside cover picture shows the culmination of a rational drug discovery program of Stat3 inhibitors. Computational modeling of the most potent salicylic acid-based therapeutic shows excellent occupation of the Stat3-SH2 domain, thereby inhibiting its homodimerization. For details, see the communication by P. T. Gunning et al. on p. 1959 ff.
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Transcript of Inside Cover: Disruption of Transcriptionally Active Stat3 Dimers with Non-phosphorylated, Salicylic...
The inside cover picture shows the culmination of a rational drug discovery programof Stat3 inhibitors. Computational modeling of the most potent salicylic acid-basedtherapeutic shows excellent occupation of the Stat3-SH2 domain, thereby inhibitingits homodimerization. For details, see the communication by P. T. Gunning et al. onp. 1959 ff.
Inside Cover
The inside cover picture shows the culmination of a rational drug discovery programof Stat3 inhibitors. Computational modeling of the most potent salicylic acid-basedtherapeutic shows excellent occupation of the Stat3-SH2 domain, thereby inhibiting itshomodimerization. For details, see the communication by P. T. Gunning et al. onp. 1959 ff.