inoculation
1
inoculati on ingesti on Sand fly Vertebrate host Transformation Attachment and phagocytosis Multiplication and reinfection Release from macrophages Multiplicatio n Transformation Protozoan parasites (proto = first; zoan = animal) Small (usually microscopic) single-celled organisms Life cycle can be divided into 2 stages depending on the host: Sand fly vector = Leishmania promastigotes Human or other vertebrate = Leishmania amastigotes Leishmania fact sheet What are Leishmania parasites? Life cycle of Leishmania parasites Form of Leishmania within human or other vertebrate host’s cells (have resorbed their flagellum) Size: 2-6 mm Shape: ovoid Characteristics: central nucleus Leishmania amastigotes Different parasites cause different forms of the disease Flagellum Form of Leishmania within sand fly vector: • Can move in the direction of their flagellum • Can be cultured Leishmania promastigotes Amastigote s Promastigot es Cutaneous lesihmaniasis Visceral lesihmaniasis
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Multiplication. Release from macrophages. Transformation. Sand fly. ingestion. inoculation. Vertebrate host. Multiplication and reinfection. Attachment and phagocytosis. Transformation. Leishmania fact sheet. What are Leishmania parasites?. - PowerPoint PPT Presentation
Transcript of inoculation
inoculation
ingestion
Sand fly
Vertebrate host
Transformation
Attachment andphagocytosis
Multiplication and reinfection
Release from macrophages
Multiplication
Transformation
Protozoan parasites (proto = first; zoan = animal) Small (usually microscopic) single-celled organismsLife cycle can be divided into 2 stages depending on the host:
Sand fly vector = Leishmania promastigotes Human or other vertebrate = Leishmania amastigotes
Leishmania fact sheetWhat are Leishmania parasites?
Life cycle of Leishmania parasites
Form of Leishmania within human or other vertebrate host’s cells (have resorbed their flagellum)Size: 2-6 mm Shape: ovoidCharacteristics: central nucleus
Form of Leishmania within human or other vertebrate host’s cells (have resorbed their flagellum)Size: 2-6 mm Shape: ovoidCharacteristics: central nucleus
Leishmania amastigotes
Different parasites cause different forms of the disease
Flagellum
Form of Leishmania within sand fly vector:• Can move in the direction of their flagellum• Can be cultured
Leishmania promastigotes
Amastigotes
Promastigotes
Cutaneous lesihmaniasis Visceral lesihmaniasis
