Innovation For Health by DSM Chief Innovation Officer
23
Future proof Healthcare through innovation? Approaches to address Health & Wealth in our society Rob van Leen Chief Innovation Officer, Royal DSM Boegbeeld Life Science & Health February 2014
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Transcript of Innovation For Health by DSM Chief Innovation Officer
Future proof Healthcare through innovation? Approaches to address Health & Wealth in our society
Rob van Leen Chief Innovation Officer, Royal DSM Boegbeeld Life Science & Health February 2014
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Topsector Life Sciences & Health
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Regiegroep Life Sciences & Health
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Topsector vision: Health and wealth for society and economy
LIFE SCIENCES
& HEALTH
Society Economy
Hea
lth
W
ealt
h
QUALITY OF LIFE
PRODUCTIVITY
AFFORDABILITY BUSINESS
The topsector envisions a thriving Dutch Life Sciences & Health sector that develops innovative health solutions based on scientific excellence that:
> improve QUALITY OF LIFE of patients
> support the AFFORDABILITY of healthcare
> increase PRODUCTIVITY within and beyond healthcare
> create BUSINESS VALUE in the Netherlands
Source: topsectorplan; cahier no. IV
Vision
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Regiegroep Life Sciences & Health
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Three objectives which together contribute to affordable, high-quality healthcare
PREVENTION CURE CARE
1. Maintain health, prevent healthcare
2. Maximize effect, minimize trauma
3. Manage disease extramurally
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Regiegroep Life Sciences & Health
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• Molecular Diagnostics
• Imaging and image guided therapies
• Home care and self-management
• Regenerative medicine
• Pharmacotherapy
• One health • Specialized nutrition, health and disease
• Health technology assessment & quality of life
• Enabling technologies & infrastructure
• Solutions to neglected diseases
LSH Roadmaps
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Regiegroep Life Sciences & Health
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Efficient valorization requires 7 critical success factors
5
IDEA GENERATION Increase the number of promising ideas
DEVELOPMENT Accelerate the development process and heighten the chance of success
APPLICATION Accelerate and broaden effective application (nationally and internationally)
Demanding Dutch market and patients, a portal into Europe/ the rest of the World
1
Optimized legal and regulatory landscape 2
Sufficient well educated, entrepreneurial people 3
Good accessibility to the right capital 4
Shared public-private innovation infrastructure 6
The Netherlands as one self-organized Life Sciences & Health sector 7
Strong, accessible (fundamental) knowledge base 5
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Regiegroep Life Sciences & Health
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• Transition period is necessary: Identify ‘pearls’ and continue support, safeguard data infrastructure and valorization initiatives.
• Capitalize on built up PPS expertise and networks to attract EU money (Horizon 2020, in e.g. IMI-2)
• Strenghten operational capacity of the Topsector (TKI-Office) • Budget made available by EZ – efforts to include VWS and OCW
Transition from TopInstitutes BMM, CTMM, TiP & NGI
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Meer informatie: www.regiegroeplsh.nl www.lshplaza.nl www.zonmw.nl
Sustainable
Manufacturing/
Raw Materials Energy Security
Health Food & Nutrition
Security
People
Planet
Profit Sustainable Innovation Themes
a Sustainable Company
20%
Innovation Sales 2015
@ ~5% higher Gross Margins
Top Quartile
McKinsey Innovation
Benchmark 2012
€1B
Disruptive Platforms, 2020
Building an intrinsically innovative company
Accelerating and supporting innovation
DSM Innovation Center
EBA Biomedical
EBA Advanced
Surfaces
EBA Bio-based
Products & Services
Business Incubator
New Business Development
CTO Office
Venturing
Excellence in Innovation
Licensing
Accelerators
Why do we need Open Innovation?
99.999996% of world population outside DSM!
Networks needed!
DSM
Open Innovation in biomedical materials
Licensing
In
Venturing
Spin in
Joint
Business
Developments
Acquisitions
Licensing
Out
Spin out/off
Divestments
R&D services
Joint
R&D
Device design;
Exclusive material developments
Actamax
Joint-venture
Scientific Advisory Board
& other Consultants
DSM Biomedical
materials improve
over 4.4 million
people’s lives,
every day.
A world class portfolio of biomedical materials
UHMWPE
biomaterials Coatings Drug delivery Silicone
hydrogels
Biomedical
polyurethanes
Natural Materials Polymers &
Metals
Bio
Commercialization
Mechanical Devices ECMs
Page
Escalation of healthcare costs
Severity / Invasiveness of intervention
Cost
per
inte
rventi
on
Total disease cost
preventive
curative
Healthy Life style
Food & Sport
Medication
& non-invasive
treatment
Surgery
Nurture
Health
Maintain
Health
Repair
Restore
Germany
The Netherlands
United States
United Kingdom
Source: Troesch et al BJN 2012
Micronutrient intake in Western countries
Example vitamin D: the inadequate status
impacts a number of body functions
Classical role of vitamin D: bone health
• Improves bone mineral density through
calcium absorption and deposition
• Necessary to prevent rickets & osteomalacia
Emerging health benefits of vitamin D
• Muscle - Reduces risk of falling by
improving muscle strength
• Immunity - Strengthens the immune system
- Reduces risk of multiple sclerosis
and diabetes type I and II
• Cardiovascular - Lowers blood pressure
• Cancer - Inhibits cell proliferation
osteoporotic
normal
Page 20
HALS-UH
Nurture
Health
Maintain
Health
Repair
Restore
The health continuum : example of the knee
To conclude
Prevention, Cure and Care, together with Diagnostics all need integrated
attention to improve peoples lives and get a hold on healthcare costs
Open Innovation and Collaboration between all parts of the
“health value chain” is essential to accomplish breakthrough solutions
Topsector LSH increasingly integrates, facilitates and stimulates the complete
public private innovation infrastructure with all parties involved
DSM has competences in both Life Sciences and Materials Sciences which
contribute to a brighter life for people today and generations to come
