7/25/2019 Inhibitors in Controlling Metabolism

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~ Inhibitors in controlling metabolism

(Example of negative feedback (homeostasis)

When any substance is needed, a particular pathway is activated to

produce it. When enough has been produced, the pathway is deactivated.

This is because of enzymes are inhibited by the end product. If too much

product begins to accumulate, this inhibits one of the enzymes in pathway,

but if too short supply, inhabitation lifted making pathway active.

Incase of controlling of rate of respiration = An excess of ATP relative to

ADP inhibits the phosphokinase enzyme, thereby slowing down the rate at

which glucose is respired.