IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP Provide results for sterile...

21
IMPRIMIS IS YOUR PARTNER Commitment to affordability Providing high-quality formulations Solving unmet needs through innovation VIP customer service

Transcript of IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP Provide results for sterile...

Page 1: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

IMPRIMIS IS YOUR PARTNER

Commitment to affordability

Providing high-quality formulations

Solving unmet needs through innovation

VIP customer service

Page 2: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

Quality innovation that’s accessible.We are patient focused and we do this by partnering with healthcare providers to ensure high quality medications are delivered at affordable prices for your patients.

Our approach takes into account three core aspects to address the needs in the ophthalmic market.

Our Commitment to You.

SETTING THE STANDARD IN COMMITMENT TO QUALITY

All ImprimisRx® pharmacies are FDA inspected and use bulk active and inactive substances obtained from FDA-registered manufacturers, accompanied by a certificate of analysis.

1

SOLVING UNMET NEEDS THROUGH INNOVATION

Imprimis doesn’t believe healthcare providers should “accept” high prices and drug shortages. We strive to solve these challenges through innovative compounded alternatives to combat high priced drugs, and those inaccessible due to drug shortages.

We listen to specific challenges your patients face—like lack of insurance coverage and issues with compliance—and we deliver solutions.

2

MAKING MEDICATIONS ACCESSIBLE AND AFFORDABLE

We built our business on making sure patients have access to affordable medications. We partner with physicians like you to successfully do this within the ophthalmic market with all of our portfolios. We will continue to innovate to ensure your patients have access to the medications they need.

3

Mark Baum, CEO

A note from the CEO.

1

Page 3: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

HOW IMPRIMIS IS DIFFERENT

PrescriberHospitalsASCs

PrescriberHospitalsASCs

Production

Pharmacy Benefit Managers

Insurers

Wholesalers

Pharmacy Retailers

Production and Dispensing at

Imprimis Traditional Pharmacy

PatientPatient

Imprimis is collapsing the value chain by eliminating the additional steps in costs during the prescription process. The efficiency of our business model allows us to quickly innovate and deliver high quality medications to patients at low costs.

2

Page 4: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

WHO WOULD YOU TRUST IN PROVIDING MEDICATIONS FOR YOUR PATIENTS?

10 IMPORTANT QUESTIONS YOU SHOULD ASK WHEN CHOOSING A PHARMACY

Your patients are important to us and we want them to receive the highest quality medications. Don’t trust your patient’s safety with just anyone. ImprimisRx® can provide you with the correct answers to all of the questions below.

How long has your pharmacy been making these formulations? Have they served over 3 million patient eyes?

Are all of the formulations tested in an FDA-registered laboratory?

Is the laboratory testing every batch of your formulations for potency, sterility, and endotoxins? Can you provide me with a report for all of these with every shipment I receive?

Is beyond use date (BUD) determined using validated stability indicating methods and data from an FDA-registered laboratory?

1 Where are your formulations made? Does your company own and manage these facilities?

2345

6789

10

Does your laboratory and company test the active pharmaceutical ingredient (API) raw material for potency before making new batches?

Is your supplier using validated warehouses to store finished product?

Can I order and store inventory of your product on my shelf to provide to patients when they need them?

Does your supplier follow cGMP requirements when making and testing all of your formulations?

Does your pharmacy participate in MedWatch: The FDA Safety Information and Adverse Event Reporting Program?

QUALITY

3

Page 5: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

THE IMPRIMIS COMMITMENTQuality compounded formulations brought to you by Imprimis

503A Pharmacy Requirements

503B Outsourcing Facility Requirements

API TESTING / RAW MATERIALS No requirement Identity test for each incoming lot

POTENCY TESTING No requirement All finished product lots

STERILITY TESTING Sterile lots per USP <71> Provide results for sterile lots per USP <71>

ENDOTOXIN TESTING Sterile injectable lots per USP <85> Sterile injectable lots per USP <85>

PRE-SHIPMENT QUARANTINE Not required, but recommended 14 days for sterility result

ENVIRONMENTAL TESTING Every 6 months Continuous (24 hours/day; 7 days/week)

TEST RESULTS INCLUDED WITH ORDER No requirement Sterility resultsEndotoxin results

BEYOND USE DATING (EXPIRATION)Literature and pharmacist experience based, but not required. Stability study over time recommended.

Stability study data from three lotsusing validated stability indicating methods

Our 503B-FDA Registered Outsourcing facility is inspected by the FDA

We use bulk active and inactive substances obtained from FDA-registered manufacturers, accompanied by a certificate of analysis

Release and stability testing performed at FDA-registered labs Sterility, endotoxin and potency testing performed on each batch

Continuous environmental monitoring to maintain product quality standards

IMPRIMIS PROVIDES STERILE COMPOUNDED FORMULATIONS YOU CAN TRUST

To contact an Imprimis Pharmacist, call 844-4IMMYRX (844-446-6979)

or email [email protected] today!

QUALITY

4

Page 6: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

Injectable Formulations Unit Size503A

Bill to OfficeFREE Shipping to Office

503BBill to Office

FREE Shipping to Office

Patient PriceBill to Patient

FREE Shipping to Office

Dropless® FormulationsTri-Moxi® (Triamcinolone acetonide and moxifloxacin) PF 15mg/1mg/mLNDC# 71384-0510-01

Single-use vial $24.20 per vial $484 per box of 20 vials $55 per vial

Other Injectable FormulationsDex-Moxi®(Dexamethasone sodium phosphate and moxifloxacin) PF 1mg/5mg/mLNDC# 71384-0512-01

Single-use vial $27.50 per vial $550 per box of 20 vials $55 per vial

Dex-Moxi-Ketor® (Dexamethasone sodium phosphate, moxifloxacin and ketorolac tromethamine) PF1mg/0.5mg/0.4mg/mLNDC# 71384-0513-01

Single-use vial $30.25 per vial $605 per box of 20 vials $55 per vial

Moxifloxacin PF 5mg/mLNDC# 71384-0511-01 Single-use vial $16.50 per vial $330 per box

of 20 vials N/A

Moxifloxacin PF 1mg/mLNDC# 71384-0509-01 Single-use vial N/A $330 per box

of 20 vials N/A

Lidocaine hydrochloride/Epinephrine in BSS (PF/SF) (0.75/0.025)%NDC# 71384-0640-01 (Shipped frozen)

Single-use vial $16.50 per vial $330 per box of 20 vials N/A

Phenylephrine hydrochloride/Lidocaine hydrochloride (PF/SF) (1.5/1)%NDC# 71384-0650-01

Single-use vial $16.50 per vial $330 per boxof 20 vials N/A

Availability and pricing for all formulations are indicated below.

*For professional use only. ImprimisRx specializes in customizing medications to meet unique patient and practitioner needs. ImprimisRx dispenses only to individually identified patients with valid prescriptions. No compounded medication is reviewed by the FDA for safety or efficacy. ImprimisRx does not compound essentially copies of commercially available products. References available upon request.

Injectables are only available to ship out of 503A with an individual patient prescription in states our 503B facility cannot ship to.

Commonly Requested Formulations*

PF = Preservative Free

SURGICAL FORMULATION PRICING

5

Page 7: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

*For professional use only. ImprimisRx specializes in customizing medications to meet unique patient and practitioner needs. ImprimisRx dispenses only to individually identified patients with valid prescriptions. No compounded medication is reviewed by the FDA for safety or efficacy. ImprimisRx does not compound essentially copies of commercially available products. References available upon request.

Topical Formulations Unit Size 503AFREE Shipping to Office

503BFREE Shipping to Office

Mydriatic 2 (Tropicamide and phenylephrine hydrochloride) (1/2.5)%NDC# 71384-0633-10

10mL N/A $275 per box of 10 bottles

Mydriatic 3**(Tropicamide, cyclopentolate, and phenylephrine hydrochloride) PF (1/1/2.5)%NDC# 71384-0631-01

1mL $17.00 per bottle N/A

Mydriatic 4** (Tropicamide, proparacaine hydrochloride, phenylephrine hydrochloride, and ketorolac tromethamine) PF (1/0.5/2.5/0.5)%NDC# 71384-0632-01

1mL $17.00 per bottle N/A

Mydriatic 4 (Tropicamide, proparacaine hydrochloride, phenylephrine hydrochloride, and ketorolac tromethamine) (1/0.5/2.5/0.5)%NDC# 71384-0632-05

5mL N/A $132 per pack of 2 bottle

Oral Formulations Unit Size 503AFREE Shipping to Office

503BFREE Shipping to Office

IV Free® Formulations

MKO Melt® Sublingual Lemon (Midazolam, ketamine HCl, and ondansetron) (3/25/2)mgNDC# 71384-0630-21

1 Melt $16.50 Per 1 Melt

$346.50 per box of 21 Melts

Commonly Requested Formulations*Availability and pricing for all formulations are indicated below.

SF = Sulfite FreePF = Preservative Free

** Additional $10 for cold overnight shipping.

SURGICAL FORMULATION PRICING

6

Page 8: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

*For professional use only. ImprimisRx specializes in customizing medications to meet unique patient and practitioner needs. ImprimisRx dispenses only to individually identified patients with valid prescriptions. No compounded medication is reviewed by the FDA for safety or efficacy. ImprimisRx does not compound essentially copies of commercially available products. References available upon request.

Important: Patients may need to take more than one eye drop product pursuant to multiple dosing regimens, as directed by his or her prescriber, in order for the active ingredients to remain effective throughout the day.

PF = Preservative Free

** Additional $10 for cold overnight shipping.

Simple Drops® FormulationsPreservative-Free Unit Size 503A

FREE Shipping

Lat** (Latanoprost PF) 0.005% NDC# 71384-0515-07

7.5mL $75.90

per bottle

Dor (Dorzolamide PF) 2%NDC# 71384-0516-10

10mL $66.00

per bottle

Brim-Dor® (Brimonidine and dorzolamide PF) (0.15/2)%NDC# 71384-0518-10

10mL $107.80

per bottle

Tim-Lat® ** (Timolol and latanoprost PF) (0.5/0.005)%NDC# 71384-0517-05

5mL $107.80 per bottle

Tim-Dor-Lat® ** (Timolol, dorzolamide, and latanoprost PF)(0.5/2/0.005)%NDC# 71384-0521-05

5mL $129.80

per bottle

Tim-Brim-Dor® (Timolol, brimonidine, and dorzolamide PF) (0.5/0.15/2)%NDC# 71384-0520-05

5mL(2 bottles per shipment)

$129.80 per 2 bottles

Tim-Brim-Dor-Lat® ** (Timolol, brimonidine, dorzolamide, and latanoprost PF) (0.5/0.15/2/0.005)%NDC# 71384-0522-05

5mL $151.80

per bottle

Triple/Quad Kit** $173.80 per kit

Tim-Brim-Dor (0.5/0.15/2)%

5mL

Tim-Brim-Dor-Lat (0.5/0.15/2/.005)%

5mL

Commonly Requested Formulations*Availability and pricing for all formulations are indicated below.

TOPICAL FORMULATION PRICING

7

Page 9: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

*For professional use only. ImprimisRx specializes in customizing medications to meet unique patient and practitioner needs. ImprimisRx dispenses only to individually identified patients with valid prescriptions. No compounded medication is reviewed by the FDA for safety or efficacy. ImprimisRx does not compound essentially copies of commercially available products. References available upon request.

LessDrops® Formulations Unit Size 503AFREE Shipping to Office

503BFREE Shipping to Office

SHIP TO PATIENTIncludes FREE Shipping

Pred-Gati-Brom® (Prednisolone acetate, gatifloxacin, andbromfenac) (1/0.5/0.075)%NDC# 71384-0504-05

5mL $41.80per bottle N/A $52.80

per bottle

Pred-Gati-Brom(Prednisolone acetate, gatifloxacin andbromfenac) (1/0.5/0.075)%NDC# 71384-0504-08

8mL $77.00per bottle N/A $82.50

per bottle

Pred-Gati-Brom (Prednisolone sodium phosphate, gatifloxacin, and bromfenac) (1/0.5/0.075)%NDC# 71384-0550-05

5mL $41.80 per bottle N/A $52.80

per bottle

Pred-Gati-Brom (Prednisolone sodium phosphate, gatifloxacin, and bromfenac) (1/0.5/0.075)%NDC# 71384-0550-08

8mL $77.00 per bottle N/A $82.50

per bottle

Pred-Moxi-Nepaf ®(Prednisolone acetate, moxifloxacin and nepafenac) (1/0.5/0.1)%NDC# 71384-0320-05

5mL N/A $836 per box of 20 bottles N/A

Pred-Moxi-Nepaf (Prednisolone acetate, moxifloxacin, and nepafenac) (1/0.5/0.1)%NDC# 71384-0320-08

8mL N/A $1,540 per box of 20 bottles N/A

Pred-Moxi® (Prednisolone acetate and moxifloxacin) (1/0.5)%NDC# 71384-0300-05

5mL N/A $704 per box of 20 bottles N/A

Commonly Requested Formulations*

Availability and pricing for all formulations are indicated below.

TOPICAL FORMULATION PRICING

8

Page 10: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

*For professional use only. ImprimisRx specializes in customizing medications to meet unique patient and practitioner needs. ImprimisRx dispenses only to individually identified patients with valid prescriptions. No compounded medication is reviewed by the FDA for safety or efficacy. ImprimisRx does not compound essentially copies of commercially available products. References available upon request.

LessDrops® Formulations Unit Size 503AFREE Shipping to Office

503BFREE Shipping to Office

SHIP TO PATIENTIncludes FREE Shipping

Pred-Gati® (Prednisolone acetate and gatifloxacin) (1/0.5)%NDC# 71384-0502-05

5mL $35.20per bottle N/A $49.50

per bottle

Pred-Brom® (Prednisolone phosphate and bromfenac) (1/0.075)%NDC# 71384-0552-05

5mL $35.20per bottle N/A $49.50

per bottle

Pred-Nepaf® (Prednisolone acetate and nepafenac) (1/0.1)%NDC# 71384-0400-05

5mL N/A $704 per box of 20 bottles N/A

Commonly Requested Formulations*

Other Topical Formulations Unit Size 503AFREE Shipping to Office

503BFREE Shipping to Office

SHIP TO PATIENTIncludes FREE Shipping

Prednisolone Acetate PF 1%NDC# 71384-0501-05

5mL $36.30 per bottle

$363 per box of 10 bottles $44.00 per bottle

Atropine0.01%NDC# 71384-0571-05

5mL N/A

Atropine0.025%NDC# 71384-0572-05

5mL N/A

Atropine0.05%NDC# 71384-0573-05

5mL N/A

forforfor

$59.00$99.00

$119.00

1 bottle2 bottles3 bottles

Availability and pricing for all formulations are indicated below.

forforfor

$59.00$99.00

$119.00

1 bottle2 bottles3 bottles

forforfor

$59.00$99.00

$119.00

1 bottle2 bottles3 bottles

forforfor

$59.00$99.00

$119.00

1 bottle2 bottles3 bottles

forforfor

$59.00$99.00

$119.00

1 bottle2 bottles3 bottles

forforfor

$59.00$99.00

$119.00

1 bottle2 bottles3 bottles

TOPICAL FORMULATION PRICING

9

Page 11: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

Commonly Requested Formulations*

*For professional use only. ImprimisRx specializes in customizing medications to meet unique patient and practitioner needs. ImprimisRx dispenses only to individually identified patients with valid prescriptions. No compounded medication is reviewed by the FDA for safety or efficacy. ImprimisRx does not compound essentially copies of commercially available products. References available upon request.

PF = Preservative Free

Total Tears® FormulationsPreservative-Free Unit Size 503A

FREE Shipping503B

FREE Shipping to Office

Klarity Drops®(Glycerin and dextran based vehicle ophthalmic solution PF) NDC# 71384-0500-10

10mL $22.00per bottle

$352 per boxof 20 bottles

Klarity-A® Drops (Azithromycin 1% ophthalmic solution PF)NDC# 71384-0220-03

3.5mL N/A

Klarity-B® Drops(Betamethasone sodium phosphate 0.1%ophthalmic solution PF)NDC# 71384-0560-05

5.5mL N/A

Klarity-C Drops®(Cyclosporine 0.1% ophthalmic emulsion PF) NDC# 71384-0514-05

5.5mL $165.00/ 3 bottles

$440 per boxof 10 bottles

Klarity-L® Drops(Loteprednol etabonate 0.5% ophthalmic suspension PF)NDC# 71384-0210-05

5mL N/Aforforfor

$59.00$99.00

$119.00

1 bottle2 bottles3 bottles

forforfor

$59.00$99.00

$119.00

1 bottle2 bottles3 bottles

forforfor

$59.00$99.00

$119.00

1 bottle2 bottles3 bottles

Availability and pricing for all formulations are indicated below.

TOPICAL FORMULATION PRICING

10

Page 12: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

*For professional use only. ImprimisRx specializes in customizing medications to meet unique patient and practitioner needs. ImprimisRx dispenses only to individually identified patients with valid prescriptions. No compounded medication is reviewed by the FDA for safety or efficacy. ImprimisRx does not compound essentially copies of commercially available products. References available upon request.

Formulation List of NDCs (Sorted Alphabetically)

Formulations* Concentration Unit Size NDC

Atropine (0.01%) 5mL 71384-0571-05

Atropine (0.025%) 5mL 71384-0572-05

Atropine (0.05%) 5mL 71384-0573-05

Azithromycin in Klarity (1%) 3.5mL 71384-0220-03

Betamethasone in Klarity (0.1%) 5.5mL 71384-0560-05

Brim-Dor PF (Brimonidine and dorzolamide PF) (0.15/2)% 10mL 71384-0518-10

Cyclosporine in Klarity (Cyclosporine ophthalmic emulsion PF) (0.1%) 5.5mL 71384-0514-05

Dex-Moxi (Dexamethasone sodium phosphate and moxifloxacin hydrochloride)

(1mg/0.5mg/mL) Single-use vial 71384-0512-01

Dex-Moxi-Ketorolac (Dexamethasone sodium phosphate, moxifloxacin, and ketorolac tromethamine)

(1mg/0.5mg/0.4mg/mL) Single-use vial 71384-0513-01

Dorzolamide PF (2%) 10mL 71384-0516-10

Hyaluronidase (175 units/ml) (175 units/mL) Single-use vial 71384-0570-01

Klarity (Glycerin and dextran based vehicle ophthalmic solution PF) N/A 10mL 71384-0500-10

Latanoprost PF (0.005%) 7.5mL 71384-0515-07

Buffered lidocaine hydrochloride (1%) 5mL 71384-0661-05

Buffered lidocaine hydrochloride (2%) 5mL 71384-0662-05

Lido-Epi (Lidocaine hydrochloride/epinephrine in BSS PF/SF) (0.75/0.025)% Single-use vial 71384-0640-01

Loteprednol in Klarity (Loteprednol 0.5% ophthalmic suspension PF)

(0.5%) 5mL 71384-0210-05

MKO Melt (Midazolam, ketamine HCl, and ondansetron) (3/25/2)mg 1 Melt 71384-0630-21

Moxifloxacin 1mg/mL Single-use vial 71384-0509-01

Moxifloxacin 5mg/mL Single-use vial 71384-0511-01

Mydriatic-2 (Tropicamide and phenylephrine hydrochloride) (1/2.5)% 10mL 71384-0633-10

Mydriatic-3 (Tropicamide, cyclopentolate, and phenylephrine hydrochloride)

(1/1/2.5)% 1mL 71384-0631-01

PF = Preservative FreeSF= Sulfite Free

FORMULATION PRICING

11

Page 13: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

Mydriatic-4 (Tropicamide, proparacaine hydrochloride, phenylephrine hydrochloride, and ketorolac tromethamine)

(1/0.5/2.5/0.5)% 1mL 71384-0632-01

Mydriatic-4 (Tropicamide, proparacaine hydrochloride, phenylephrine hydrochloride, and ketorolac tromethamine)

(1/0.5/2.5/0.5)% 5mL 71384-0632-05

Phenyl-Lido (Phenylephrine hydrochloride/lidocaine hydrochloride PF/SF) (1.5/1)% Single-use vial 71384-0650-01

Pred Acetate suspension (Prednisolone acetate PF) (1%) 5mL 71384-0501-05

Pred-Brom solution (Prednisolone sodium phosphate and bromfenac)

(1/0.075)% 5mL 71384-0552-05

Pred-Gati suspension (Prednisolone acetate and gatifloxacin) (1/0.5)% 5mL 71384-0502-05

Pred-Gati-Brom suspension (Prednisolone acetate, gatifloxacin, and bromfenac)

(1/0.5/0.075)% 5mL 71384-0504-05

Pred-Gati-Brom solution (Prednisolone sodium phosphate, gatifloxacin, and bromfenac)

(1/0.5/0.075)% 5mL 71384-0550-05

Pred-Gati-Brom suspension (Prednisolone acetate, gatifloxacin,and bromfenac)

(1/0.5/0.075)% 8mL 71384-0504-08

Pred-Gati-Brom solution (Prednisolone sodium phosphate, gatifloxacin, and bromfenac)

(1/0.5/0.075)% 8mL 71384-0550-08

Pred-Moxi suspension (Prednisolone acetate and moxifloxacin) (1/0.5)% 5mL 71384-0300-05

Pred-Moxi-Nepaf suspension (Prednisolone acetate, moxifloxacin, and nepafenac)

(1/0.5/0.1)% 5mL 71384-0320-05

Pred-Moxi-Nepaf suspension (Prednisolone acetate, moxifloxacin, and nepafenac)

(1/0.5/0.1)% 8mL 71384-0320-08

Pred-Nepaf suspension (Prednisolone acetate and nepafenac) (1/0.1)% 5mL 71384-0400-05

Tim-Brim-Dor (Timolol, brimonidine, and dorzolamide) PF (0.5/0.15/2)% 10mL 71384-0520-05

Tim-Brim-Dor-Lat (Timolol, brimonidine, dorzolamide, and latanoprost) PF

(0.5/0.15/2/0.005)% 5mL 71384-0522-05

Tim-Dor-Lat (Timolol, dorzolamide, and latanoprost) PF (0.5/0.15/2)% 5mL 71384-0521-05

Tim-Lat (Timolol and latanoprost) PF (0.5/0.005)% 5mL 71384-0517-05

Tri-Moxi (Triamcinolone acetonide and moxifloxacin) (15mg/1mg/mL) Single-use vial 71384-0510-01

Formulations* Concentration Unit Size NDC

Formulation List of NDCs (Sorted Alphabetically)

PF = Preservative FreeSF = Sulfite Free*For professional use only. ImprimisRx specializes in customizing medications to meet unique patient and practitioner needs. ImprimisRx dispenses only to individually identified patients with valid prescriptions. No compounded medication is reviewed by the FDA for safety or efficacy. ImprimisRx does not compound essentially copies of commercially available products. References available upon request.

FORMULATION PRICING

12

Page 14: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

HOW TO ORDEROrder from our FDA-Registered 503B Facility.

Ordering from our FDA-Registered 503B Outsourcing Facility is easy. All available formulations are sold in bulk and shipped directly to the office.

Visit https://order.imprimisrx.com to place your order online today. How to get started:

ORDER ONLINE

All 503B orders include free shipping.

If you do not have an account set up with us yet, please visit the above URL and navigate to Account > Register.

Once your account information is submitted, your account should be approved within 24 hours.

If you would like to place an immediate order, please contact our Customer Care at (844) 446-6979, and they will expedite it for you.

HOW TO ORDER

13

Page 15: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

HOW TO ORDER FOR YOUR PATIENTS

3 EASY WAYS TO PLACE AN ORDER WITH AN IMPRIMISRX 503A PATIENT SPECIFIC PHARMACY

e-Scribe using your existing EMR system (Page 15 provides instructions for EMR)Fax your completed prescription order form to (855) 405-4669Call toll-free at (844) 4-IMMYRX (844-446-6979) and place your order with a pharmacist

COMPLETE REQUIRED INFORMATIONPlease include the following required information when placing your order.

Patient name, date of birth, address and phone numberPatient allergiesFormulation Quantity and number of refillsPrescribing instructionsFull patient demographics are required for controlled substances*

RELAXWe’ve got it from here.Once your order is received, it will be processed within 72 hours. If a patient is paying for the prescribed medication, they will be contacted and the medication will ship directly to their home. For your convenience, you can provide them a patient information sheet (we can supply to you) to help reduce call backs to your staff.

*Applies to MKO Melt® compounded formulation.

Order from our Patient Specific Pharmacy.

HOW TO ORDER

14

Page 16: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

STEP 1: SELECT YOUR PATIENT.

e-Scribing BenefitsBy e-scribing through your existing Electronic Medical Record (EMR) system, your prescriptions will be sent directly to our pharmacy for processing which may expedite turnaround time.

INSTRUCTIONSPlease follow the steps below to properly start utilizing your EMR system.

1 Locate the pharmacyYou can find the ImprimisRx pharmacy in your EMR system as identified below:

2 Complete the informationOnce the pharmacy is chosen, please complete the following information:

• Patient information (please be sure your patient profile has name, phone number,

address and date of birth complete in your EMR so demographics will transmit to

our system)

• Search medication and select (Search one of the ingredients of the compound.

Example: search "cyclosporine" for Cyclosporine in Klarity/Klarity-C)

• Select the correct quantity

Please note certain formulations have more than one fill size. Please be sure to

select the preferred fill size/quantity you wish dispensed to your patient. Klarity-C is

sold in 3 bottles (5.5mL bottles), totaling 16.5mL. Please save 16.5mL as the default

for Klarity-C.

ImprimisRx NJ, LLC 1705 Route 46, Suite 4 Ledgewood, NJ 07852866-792-7328

ORDERING THROUGH YOUR EMR SYSTEM

15

HOW TO ORDER

Page 17: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

3 Provide Instructions for Use:Please indicate dosing instructions—how the formulation will be administered, volume to be used, and how often the drops are to be applied.

STEROID-ANTIBIOTIC-ANTI-INFLAMMATORY AGENT 5ML or 8ml(ie: Prednisolone-Gatifloxacin-Bromfenac - 5ml)

Instill ______ drop(s) into affected eye _______ times a day for ___________ days.

4 Include Doctor NotesPlease include in the Notes to Pharmacy field.

• Dispense ImprimisRx Compound (ie: "Prednisolone Acetate-Gatifloxacin-Bromfenac"

or "Pred-Gati-Brom"-5mL)

• Medical Necessity (ie: patient cannot tolerate commercial formulation, patient needs

double strength, etc.) Please note: financial/economic reason is not valid. *Required

• Patient allergies *Required

• Ship to Patient or Doctor, Bill to Patient or Doctor *Required

• Medication start date , Surgery date *if applicable

For assistance with EMR setup or if you have questions, please contact us at: [email protected]

ORDERING THROUGH YOUR EMR SYSTEM

X XX

*Needed only if formulation cannot be selected in EMR

16

HOW TO ORDER

Page 18: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

HOW CAN WE HELP YOU?

We Satisfy Unmet Needs. The reality is that the current healthcare market is complicated and expensive. We all know that. Our mission is to navigate this market and solve unmet patient needs.

But, what does this mean?

THE NEED FOR INNOVATIVE MEDICATIONS:

Our journey began when we recognized a need for personalized medications, which may not have been accessible to your patients before.

THE NEED FOR SUPPORT, HOW AND WHEN YOU NEED IT:

We are committed to consistently delivering world-class customer service to you.

Our friendly customer care professionals are headquartered in San Diego, CA and phone support is available Monday through Friday from 8:30 am – 8:00 pm (EDT).

THE NEED FOR TRANSPARENCY:

We built our company on a foundation of personal and professional integrity. We ask our employees to be ethically unyielding, transparent, inspire trust and ultimately take care of your patients like they would family.

THE NEED FOR AMAZING PEOPLE:

We only hire the best talent for our team. We ask for relentlessly positive attitudes and cultivate a creative, innovative culture where everyone benefits.

12

3

4

17

CUSTOMER EXPERIENCE

Page 19: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

YOUR CUSTOMER EXPERIENCE

We are here to help you and your patients!

QUESTIONS? CONTACT OUR CUSTOMER CARE AT

(844) 446-6979

Friendly team of Customer Care Advocates to take care of your patients, helping you reduce call backs to your office.

Convenience of live support Monday through Friday from 8:30 am – 8:00 pm (EDT) at (844) 446-6979.

Fast turnaround, and the ability to set your patients up on refills that may reduce the need for them to remember every month.

Need a higher level of service? We offer our VIP Advantage Program with even faster response times and access to a weekly summary reports on recent orders.

Multiple convenient ways for your patients to pay for their prescription.

18

CUSTOMER EXPERIENCE

Page 20: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

Imprimis gives back.Imprimis contributes to missions and indigent programs that

provide cataract surgery to over 2,000 patients in need every year. For every

Dropless and LessDrops prescription shipped, we donate a percentage to sight

saving missions and indigent patient support programs.

Ask about our indigent patient support program.

Contact us today at [email protected] or (844) 446-6979.

Photos courtesy of Dr. Mary Cathleen Schanzer and Dr. Lee Coleman.

Page 21: IMPRIMIS IS YOUR PARTNER · STERILITY TESTING Sterile lots per USP  Provide results for sterile lots per USP  ENDOTOXIN TESTING Sterile injectable lots per USP

ImprimisRx12264 El Camino Real, Suite 350

San Diego, CA 92130 T: 858.704.4040 | F: 858.345.1745

For more information, please email us at [email protected]

Brim-Dor, Tri-Moxi, Dex-Moxi-Ketor, Dex-Moxi, Pred-Gati, Pred-Gati-Nepaf, Pred-Brom, Pred-Gati-Ketor, Pred-Moxi, Pred-Moxi-Ketor, Pred-Nepaf, Pred-Gati-Brom, TIM-LAT, TIM-BRIM-DOR, TIM-DOR-LAT, TIM-BRIM-DOR-LAT, MKO Melt, Dropless, LessDrops, SSP Technology, Simple Drops, Total Tears, IV Free, Klarity-C Drops, Klarity-B, Klarity-A, Klarity-L, and ImprimisRx are trademarks of Harrow Health, Inc. ©2020 ImprimisRx. All rights reserved.

®

IMPO0196 Rev13G 05/20