Implementing Manufacturing Execution Systems_new

8/4/2019 Implementing Manufacturing Execution Systems_new

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IMPLEMENTING

MANUFACTURINGEXECUTION SYSTEMS:FIVE KEYS TO SUCCESS(PHARMACEUTICAL INDUSTRIES)

MUHAMAD SAIDI BIN MAT ALI

GB 100281

http://www.powerpointstyles.com/







Introduction

• ERP and APS can greatlystrengthen company’s ability tocompete, but these system do notimpact the basic manufacturing

process: production of qualitypharmaceuticals.

• MES can fill the execution gap by

deliver information that enablesthe optimization of productionactivities from order launch tofinished goods.






Case Example: Impact Of MESImplementation at Major

Pharmaceutical Company

Reduced manufacturing cycletime by 30%

Reduced WIP cycle time by 30% Reduced manual data entry timeby over 40% Reduced lead time by over 20% Reduced risk of noncompliance due to product deviations orfaulty/missing records






Five Keys to MES Success

1. Implement whereopportunity is greatest

2. Use an MES as a vehiclefor processimprovement

3. Link MES and APS/ERPsystems strategically

4. Coordinate clinical andcommercial production

5. Select the rightimplementation partner






Implement WhereOpportunity is Greatest

Inventory improvement,

FDA compliance and riskreduction,

Rapid turnover of production

lines.






Use an MES as a Vehicle forProcess Improvement

Consistent operation acrossoperators,

Standardize processesacross multiple plants withdiverse operation and

procedural dissimilarities,

Staff utilization advantages.






Link MES and APS/ERPSystems Strategically

Integration between the systemsthat control finance, supply chain and the manufacturing processes, Allow automatic scaling andsequencing of recipes andspecification,

Linkage of financial andproduction greatly improvestrategic understanding of business operations






Coordinate Clinical andCommercial Production

Accelerate the process of scalingup production recipes,

Reduce time to market,

Allows clinical production

procedure to be captured – modification or scale up can beperformed easily.






Select the RightImplementation Partner

In-depth understanding of the strategic and businessprocess framework,

Extensive experience inIT-enabling manufacturing

process redesign,

Skills to integrate MESwith ERP, APS and process

control systems.







Conclusion

MES must link to other criticalsystems in the enterprise

Seek partner with in-depth

understanding of the strategicand business process frameworkwithin which the MES operate

MES can increase the strategicagility and provide significantcost savings and regulatoryadvantages, but implementation

can be formidable.







Thank you..



Implementing Manufacturing Execution Systems_new

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